Method for treating alk-positive or ros1-positive non-small cell lung cancer

IL328396A0Pending Publication Date: 2026-07-01SHENZHEN TARGETRX INC
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Patent Information

Application Number
IL328396
Authority / Receiving Office
IL · IL
Patent Type
Applications
Current Assignee / Owner
Priority Date
2024-11-05
Filing Date
2024-11-14
Publication Date
2026-07-01

AI Technical Summary

Technical Problem

The prior art is difficult to effectively treat ALK-positive or ROS1-positive non-small cell lung cancer, especially in cases where there is no response or drug resistance to the previous treatment.

Method used

Targeted therapy is achieved by oral administration against ALK-positive and ROS1-positive non-small cell lung cancer, especially in advanced and CNS metastatic cases using Compound A or a pharmaceutically acceptable salt thereof.

Benefits of technology

Compound A showed an efficient inhibitory ability to ALK and ROS1, which can effectively inhibit the growth and division of non-small cell lung cancer cells, and prolong the patient's survival and free progression period.

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Abstract

Provided is a method for treating ALK-positive non-small cell lung cancer in a subject by means of administering a compound A or a pharmaceutically acceptable salt thereof to the subject. Further provided is a method for treating ROS1-positive non-small cell lung cancer in a subject by means of administering compound A or a pharmaceutically acceptable salt thereof to the subject.
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