Complex water-soluble polyglutamic acid compound containing zinc

IR113118BUndetermined Publication Date: 2025-09-28ALEXTAND CO LTD
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Patent Information

Application Number
IR139950140003008395
Authority / Receiving Office
IR · IR
Patent Type
Patents
Current Assignee / Owner
Priority Date
2018-09-17
Filing Date
2020-12-19
Publication Date
2025-09-28
Estimated Expiration
2040-12-19

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Abstract

A stable zinc polyglutamic acid complex that is well soluble in water was prepared by conjugating zinc to polyglutamic acid and then made into a capsule or injectable formula. Such a substance not only acts as a zinc supplier necessary for our body, but also shows an anticancer effect on cancer cells and a soothing effect on pollinosis caused by irritation of the mucous membrane by pollen. Therefore, the object of the present invention is to provide a compound that can be used in humans, animals and plants.
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Claims

[Claims]

1. A zinc / hisidine / polyglutamic acid complex prepared from hisidine, polygamma-glutamic acid and a zinc source, wherein the complex is prepared from 30 to 70 parts by weight of polygamma-glutamic acid and 30 to 150 parts by weight of zinc source based on 200 parts by weight of histidine.

2. The zinc / hisidine / polyglutamic acid complex according to claim 1, wherein the zinc source comprises at least one of zinc oxide, zinc acetate and zinc carbonate.

3. The zinc / hisidine / polyglutamic acid complex according to claim 1, wherein the complex comprises zinc in an amount of 15% by weight or more based on the total weight of the complex.

4. The zinc / hisidine / polyglutamic acid complex according to claim 1, wherein the complex is prepared by adding histidine, polygamma-glutamic acid and a zinc source to water, followed by refluxing and subsequent precipitation using a lower alcohol having 1 to 5 carbon atoms.

5. A health food composition for providing zinc comprising the zinc / hisidine / polyglutamic acid complex according to any one of claims 1 to 4.

6. A nutritional composition having anticancer activity and comprising a zinc / hisidine / polyglutamic acid complex according to the claim according to any one of claims 1 to 4.

7. An anticancer pharmaceutical composition comprising a zinc / hisidine / polyglutamic acid complex according to any one of claims 1 to 4.

8. The anticancer pharmaceutical composition according to claim 7, wherein the cancer comprises at least one of Hodgkin's lymphoma, breast cancer, glioblastoma, and lung cancer.