Amino acid-containing protein glycation inhibitor

JP2024083631A5Pending Publication Date: 2026-07-13AJINOMOTO CO INC
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Patent Information

Application Number
JP2024069274
Authority / Receiving Office
JP · JP
Patent Type
Applications
Current Assignee / Owner
Filing Date
2024-04-22
Publication Date
2026-07-13

AI Technical Summary

Technical Problem

Existing anti-glycation agents, such as plant extracts and aminoguanidine, suffer from impurities causing skin issues and safety concerns, while basic amino acids like lysine and arginine have limited efficacy and color stability problems, necessitating a more effective and safer solution for inhibiting protein glycation in skin aging and related health issues.

Method used

A combination of specific amino acids, including imino, neutral, acidic, and lactam carboxylic acids, is used to create a protein glycation inhibitor that synergistically suppresses the production of advanced glycation end products, addressing skin aging and related health conditions.

Benefits of technology

The amino acid combinations effectively inhibit the production of advanced glycation end products, reducing skin aging symptoms like wrinkles, age spots, and sagging, and treating conditions such as neurological disorders and dermatological disorders by inhibiting glycation reactions.

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Abstract

To provide compositions showing an excellent anti-glycation function and the like.SOLUTION: Provided is a protein glycation inhibitor containing as an active ingredient a combination selected from the group consisting of: (A) a combination of an imino acid-based amino acid or a salt thereof and a neutral amino acid or a salt thereof; (B) a combination of an imino acid-based amino acid or a salt thereof and a basic amino acid or a salt thereof; (C) a combination of an acidic amino acid or a salt thereof and a neutral amino acid or a salt thereof; (D) a combination of an acidic amino acid or a salt thereof and a basic amino acid or a salt thereof; (E) a combination of a lactam carboxylic acid or a salt thereof and a neutral amino acid or a salt thereof; (F) a combination of a lactam carboxylic acid or a salt thereof and a basic amino acid or a salt thereof; and (G) a combination of a lactam carboxylic acid or a salt thereof and an acidic amino acid or a salt thereof.SELECTED DRAWING: None
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