LFA3 variants and compositions and uses thereof

By developing LFA3-Fc fusion polypeptide molecules to regulate the interaction between CD2 and LFA3, the problem of difficulty in effectively regulating CD2-LFA3 interaction in the prior art is solved, and effective treatment of autoimmune diseases is achieved.

JP2025060698APending Publication Date: 2025-04-10PFIZER INC +1
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Patent Information

Application Number
JP2024218928
Authority / Receiving Office
JP · JP
Patent Type
Applications
Current Assignee / Owner
Priority Date
2018-12-21
Filing Date
2024-12-13
Publication Date
2025-04-10

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Abstract

To provide LFA3 polypeptide molecules, e.g., variant LFA3 fusion polypeptide molecules.SOLUTION: The invention includes uses, and associated methods of using the LFA3 polypeptide molecules.SELECTED DRAWING: Figure 14A
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