Dry powder formulations of thymic stromal lymphopoietin (TSLP)-binding antibodies and methods of use thereof

JP2025094236APending Publication Date: 2025-06-24MEDIMMUNE LTD
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Patent Information

Application Number
JP2025051583
Authority / Receiving Office
JP · JP
Patent Type
Applications
Current Assignee / Owner
Priority Date
2019-10-28
Filing Date
2025-03-26
Publication Date
2025-06-24
Patent Text Reader

Abstract

To provide: dry powder formulations for delivery of antibodies to thymic stromal lymphopoietin (TSLP) to a patient via inhalation, which may realize an improved method of treatment for asthmatic patients, including those with mild asthma; and a method of treatment for asthma in patients.SOLUTION: In one aspect, a dry powder formulation comprises a plurality of microparticles. The microparticles comprise: leucine; about 1 wt.% to about 10 wt.% of trileucine; and an antigen binding fragment of an anti-thymic stromal lymphopoietin (TSLP) antibody.SELECTED DRAWING: None
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Citation Information

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