Transmucosal delivery system for medicinal active ingredient to submucosa of bladder, pharmaceutical composition, and agent for treating bladder disease

JP2025094276AInactive Publication Date: 2025-06-24SEIKAGAKU KOGYO CO LTD
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Patent Information

Application Number
JP2025059920
Authority / Receiving Office
JP · JP
Patent Type
Applications
Current Assignee / Owner
Priority Date
2019-10-03
Filing Date
2025-03-31
Publication Date
2025-06-24
Estimated Expiration
Not applicable · inactive patent

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Abstract

To provide a system capable of achieving effective delivery of a pharmaceutical active ingredient administered into a bladder lumen to a submucosal tissue.SOLUTION: Provided is a transmucosal delivery system for a pharmaceutical active ingredient other than a steroid to a submucosal tissue of the bladder, comprising a conjugate of chondroitin sulfate and a hydrophobic compound, wherein the hydrophobic compound is a compound in which the pharmaceutical active ingredient and a spacer-forming molecule are covalently bonded to each other, and the spacer-forming molecule is covalently bonded to the chondroitin sulfate.SELECTED DRAWING: Figure 1
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Citation Information

Patent Citations

  • Chondroitin sulfate derivative and treatment agent for bladder diseases

    JP2017036455A

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  • Chondroitin sulfuric acid derivative and drug for treating bladder diseases

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