Recombinant gene effectors and compositions and methods of use thereof

Abstract

The present disclosure provides one or more recombinant gene effectors, as well as systems, compositions and methods of use thereof, wherein the one or more recombinant gene effectors of the present disclosure can be used to regulate a target gene in a cell (e.g., an endogenous target gene in a cell).The one or more recombinant gene effectors of the present disclosure can be operably linked to a heterologous endonuclease, such as a CRISPR / Cas protein.

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