Synthesis of selective dopamine D3 receptor antagonists / partial agonists
JP2025510800APending Publication Date: 2025-04-15THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH & HUMAN SERVICES
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Patent Information
- Application Number
- JP2024556537
- Authority / Receiving Office
- JP · JP
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2022-03-30
- Filing Date
- 2023-03-27
- Publication Date
- 2025-04-15
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Figure 2025510800000001_ABST
Abstract
A method for synthesizing (R)-N-(4-(4-(3-chloro-5-ethyl-2-methoxyphenyl)piperazin-1-yl)-3-hydroxybutyl)-1H-indole-2-carboxamide (compound 8) and intermediate compounds of formulas 5-7, 9, and 14 used in the method are described.
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