Synthesis of selective dopamine D3 receptor antagonists / partial agonists

JP2025510800APending Publication Date: 2025-04-15THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH & HUMAN SERVICES
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Patent Information

Application Number
JP2024556537
Authority / Receiving Office
JP · JP
Patent Type
Applications
Current Assignee / Owner
Priority Date
2022-03-30
Filing Date
2023-03-27
Publication Date
2025-04-15

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Abstract

A method for synthesizing (R)-N-(4-(4-(3-chloro-5-ethyl-2-methoxyphenyl)piperazin-1-yl)-3-hydroxybutyl)-1H-indole-2-carboxamide (compound 8) and intermediate compounds of formulas 5-7, 9, and 14 used in the method are described.
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