3-Azasteroid compounds for treating mitochondrial function-related diseases
JP2025518741A5Pending Publication Date: 2026-06-09NZP UK LTD
Patent Information
- Authority / Receiving Office
- JP · JP
- Patent Type
- Applications
- Current Assignee / Owner
- NZP UK LTD
- Filing Date
- 2023-06-01
- Publication Date
- 2026-06-09
AI Technical Summary
Technical Problem
Current treatments for neurodegenerative diseases, such as Parkinson's, Alzheimer's, and Huntington's, are limited in effectiveness and do not address the underlying mitochondrial dysfunction.
Method used
Development of novel bile acid derivatives that can modulate mitochondrial function, potentially rescuing dysfunctional mitochondria and providing therapeutic benefits for neurodegenerative diseases.
Benefits of technology
The bile acid derivatives show promise in restoring mitochondrial function and potentially crossing the blood-brain barrier, offering a new approach for treating neurodegenerative diseases.
✦ Generated by Eureka AI based on patent content.
Smart Images
Figure 00000000_0000_ABST
Abstract
Formula (I): 【Chemical 1】 TIFF2025518741000243.tif26170(wherein R 1 , R 2 and R 3 are as defined herein) can be used for the treatment and prevention of neurodegenerative diseases, as well as acute radiation syndrome and myalgic encephalomyelitis (ME, chronic fatigue syndrome) or post-viral syndrome (including chronic symptoms (long COVID) resulting from SARS-CoV2 infection) because the compound can rescue dysfunctional mitochondria.
Need to check novelty before this filing date? Find Prior Art