Vaccine for protection against Leptospira serotype grippotyphosa
By administering a polyvalent Leptospira vaccine containing serotypes like Portland-vere, Dadas, Copenhageni, and Bratislava, cross-protection against Leptospira Grippotyphosa is achieved in dogs, addressing the limitation of serotype-specific immunity in current vaccines.
JP2025519810APending Publication Date: 2025-06-26INTERVET INT BV
Patent Information
- Application Number
- JP2024574648
- Authority / Receiving Office
- JP · JP
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2022-06-22
- Filing Date
- 2023-06-21
- Publication Date
- 2025-06-26
AI Technical Summary
Technical Problem
Current Leptospira vaccines primarily provide serotype-specific protection, lacking cross-protection against other serotypes, which is crucial for effective immunity against Leptospira Grippotyphosa in dogs.
Method used
Administering a polyvalent Leptospira vaccine that includes serotypes such as Portland-vere, Dadas, Copenhageni, and Bratislava, which do not contain the Grippotyphosa serotype, to induce protective immunity against Leptospira Grippotyphosa in dogs.
Benefits of technology
The described method unexpectedly provides protective immunity against Leptospira Grippotyphosa in dogs, even though the vaccine does not contain the Grippotyphosa serotype, demonstrating cross-protection efficacy.
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Smart Images
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Abstract
The present invention relates to providing protective immunity against Leptospira serovar Grippotyphosa to dogs using a vaccine comprising a non-Grippotyphosa Leptospira serotype.
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Citation Information
Patent Citations
Method of providing protective immunity against heterologous leptospira strains
EP2874653A1