Film-forming delay / enteric formulations for hard shell capsules, films, and coatings
The use of an aqueous film-forming composition with low-viscosity alginate and HPMC addresses the safety and manufacturing complexity issues of existing enteric polymers, providing a GRAS capsule material for delayed or enteric release applications with improved process efficiency.
Patent Information
- Application Number
- JP2024574706
- Authority / Receiving Office
- JP · JP
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2022-06-21
- Filing Date
- 2023-06-19
- Publication Date
- 2025-06-26
AI Technical Summary
Existing enteric polymers used in capsule formulations are not generally recognized as safe (GRAS) for food and nutritional uses, and they require additional coating steps and organic solvents, which complicate the manufacturing process and may cause thermal stresses.
An aqueous film-forming composition comprising low-viscosity alginate and low-viscosity film-forming polymers, such as sodium alginate and hydroxypropyl methylcellulose (HPMC), which can be used to create capsule shells suitable for delayed or enteric release applications without the need for additional gelling agents or organic solvents.
The composition provides a GRAS capsule material for delayed or enteric release, simplifying the manufacturing process by eliminating the need for multiple coating steps and organic solvents, while maintaining effective film strength and release properties.
Smart Images
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