Salt form of a benzheterocyclic-substituted tetrahydroisoquinoline compound and method for producing the same

JP2025522524AActive Publication Date: 2025-07-15SHANGHAI JEMINCARE PHARMACEUTICALS CO LTD
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Patent Information

Application Number
JP2024575111
Authority / Receiving Office
JP · JP
Patent Type
Applications
Current Assignee / Owner
Priority Date
2022-06-20
Filing Date
2023-06-20
Publication Date
2025-07-15
Estimated Expiration
2043-06-20

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Abstract

The present invention discloses a salt form of a benzheterocyclic-substituted tetrahydroisoquinoline compound and a method for producing the same. Specifically, the present invention discloses an amorphous and a salt form of the compound represented by formula (I), and use for inhibiting NHE-mediated reverse transport of sodium ions or hydrogen ions. 【Chemical 1】 JPEG2025522524000027.jpg40169 。
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Citation Information

Patent Citations

  • Compositions and methods for inhibiting NHE-mediated antiport in the treatment of fluid retention or salt overload-related disorders and gastrointestinal disorders

    JP2012514009A

  • Compounds as C5aR inhibitors

    JP2023537062A