Solid Forms of Complex Ring Amide Derivatives

Abstract

The present invention relates to a crystalline polymorph of a compound of formula (I): JPEG2025524004000012.jpg4863, which has a powder X-ray diffraction pattern comprising at least three 2θ angular values selected from the group consisting of 7.2 ± 0.2°, 10.8 ± 0.2°, 13.8 ± 0.2°, 14.4 ± 0.2°, 14.8 ± 0.2°, 15.9 ± 0.2°, 16.4 ± 0.2°, 19.9 ± 0.2°, 20.7 ± 0.2°, 22.2 ± 0.2°, 22.6 ± 0.2°, 23.9 ± 0.2°, 24.6 ± 0.2°, 26.0 ± 0.2°, 26.3 ± 0.2°, 27.5 ± 0.2°, 30.0 ± 0.2°, 32.0 ± 0.2°, and 32.7 ± 0.2°. The present invention relates to a crystalline polymorph.

Description

Technical Field

[0001] The present invention relates to solid forms of heterocyclic amide derivatives, methods for preparing said solid forms, compositions comprising said solid forms, and methods of using them as fungicides.

Background Art

[0002] WO 2007 / 048556 discloses that certain heterocyclic amide derivatives have microbicidal activity, such as fungicidal activity. In particular, compounds of formula I, 3-difluoromethyl-1-methyl-1H-pyrazole-4-carboxylic acid (9-dichloromethylene-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl)-amide are disclosed.

Chemical Formula

Summary of the Invention

Means for Solving the Problems

[0003] New solid forms of this compound and their preparations have now been discovered. Accordingly, the present invention relates to novel crystalline forms of a heterocyclic amide derivative, said derivative having the formula I:

Chemical Formula

[0004] The crystalline polymorphs according to the present invention provide optimized handling and processing, especially on a manufacturing scale. More specifically, the crystalline polymorphs can ensure a significant improvement in shortening the filtration time.

[0005] More specifically, the crystalline polymorphs of formula I may be characterized by a powder X-ray diffraction pattern expressed in terms of 2θ angle and / or d-spacing.

[0006] The crystalline polymorph of formula I can have a powder X-ray diffraction pattern comprising at least 3 two-theta angle values selected from the group consisting of 7.2 ± 0.2°, 10.8 ± 0.2°, 13.8 ± 0.2°, 14.4 ± 0.2°, 14.8 ± 0.2°, 15.9 ± 0.2°, 16.4 ± 0.2°, 19.9 ± 0.2°, 20.7 ± 0.2°, 22.2 ± 0.2°, 22.6 ± 0.2°, 23.9 ± 0.2°, 24.6 ± 0.2°, 26.0 ± 0.2°, 26.3 ± 0.2°, 27.5 ± 0.2°, 30.0 ± 0.2°, 32.0 ± 0.2° and 32.7 ± 0.2°; preferably at least 6 two-theta angle values; preferably at least 8 two-theta angle values; more preferably at least 10 two-theta angle values.

[0007] In a preferred embodiment, the crystalline polymorph of formula I can have a powder X-ray diffraction pattern comprising at least 3 two-theta angle values selected from the group consisting of 7.2 ± 0.2°, 10.8 ± 0.2°, 13.8 ± 0.2°, 14.4 ± 0.2°, 14.8 ± 0.2°, 16.4 ± 0.2°, 20.7 ± 0.2°, 22.2 ± 0.2°, 24.6 ± 0.2°, 26.0 ± 0.2°, 27.5 ± 0.2°, 30.0 ± 0.2°, 32.0 ± 0.2° and 32.7 ± 0.2°; preferably at least 6 two-theta angle values; preferably at least 8 two-theta angle values; more preferably at least 10 two-theta angle values.

[0008] More specifically, the crystalline polymorph of Formula I can have a powder X-ray diffraction pattern having at least the following 2θ angular values: 7.2 ± 0.2°, 10.8 ± 0.2°, 13.8 ± 0.2°, 14.4 ± 0.2°, 14.8 ± 0.2°, 16.4 ± 0.2°, 20.7 ± 0.2°, 22.2 ± 0.2°, 24.6 ± 0.2° and 26.0 ± 0.2°; preferably, at least the following 2θ angular values: 7.2 ± 0.2°, 10.8 ± 0.2°, 13.8 ± 0.2°, 14.4 ± 0.2°, 14.8 ± 0.2°, 16.4 ± 0.2°, 20.7 ± 0.2°, 22.2 ± 0.2°, 24.6 ± 0.2°, 26.0 ± 0.2°, 27.5 ± 0.2°, 30.0 ± 0.2°, 32.0 ± 0.2° and 32.7 ± 0.2°; more preferably, at least the following 2θ angular values: 7.2 ± 0.2°, 10.8 ± 0.2°, 13.8 ± 0.2°, 14.4 ± 0.2°, 14.8 ± 0.2°, 15.9 ± 0.2°, 16.4 ± 0.2°, 19.9 ± 0.2°, 20.7 ± 0.2°, 22.2 ± 0.2°, 22.6 ± 0.2°, 23.9 ± 0.2°, 24.6 ± 0.2°, 26.0 ± 0.2°, 26.3 ± 0.2°, 27.5 ± 0.2°, 30.0 ± 0.2°, 32.0 ± 0.2° and 32.7 ± 0.2°.

[0009] The d-spacing values are calculated using an average wavelength of 1.540598 Å and are shown in Table 1 for the above 2θ angular values.

[0010] [Table 1]

[0011] The crystalline polymorph of the present invention can be characterized by the unit cell constants of its single crystal as shown in Table 2.

[0012] [Table 2]

[0013] In Table 2, a, b, and c are the lengths of the edges of the unit cell, and α, β, and γ are the angles of the unit cell.

[0014] In certain embodiments of the present invention, the crystalline polymorph can have the following lattice parameters: a = 8.0 ± 0.1 Å, b = 14.0 Å ± 0.1 Å, c = 17.0 Å ± 0.1 Å, α = 70.2 ± 0.2°, β = 84.1 ± 0.2°, γ = 74.4 ± 0.2°, and volume = 1724 ± 20 Å 3 。

[0015] In another embodiment, the crystalline polymorph according to the present invention can have a melting point in the range of 153 - 156 °C (peak position), preferably in the range of 154 - 155 °C (peak position). This melting point is obtained using differential scanning calorimetry (DSC) with a heating rate of 10 °C / minute.

[0016] In connection with the present invention, a polymorph is a particular crystalline form of a compound that can exist in two or more crystalline forms in the solid state. The crystalline form of a compound includes constituent molecules arranged in an orderly repeating pattern that extends in all three spatial dimensions (in contrast, an amorphous solid has no long-range order within the positions of the molecules). Different polymorphs of a compound have different arrangements of atoms and / or molecules in their crystal structures. When the compound is a biologically active compound such as a fungicide, the differences in crystal structure can result in different polymorphs with different chemical, physical, and biological properties. Properties that can be affected include crystal shape, density, hardness, color, chemical stability, melting point, hygroscopicity, suspension ability, dissolution rate, and bioavailability. Thus, a particular polymorph can have properties that are more advantageous for a particular use compared to another polymorph of the same compound. In particular, the physical, chemical, and biological properties listed above can have a significant impact on the development of manufacturing methods and formulation, especially on a manufacturing scale; the ease of combining the compound with other active ingredients and formulation components in a formulation; and / or the quality and effectiveness of a plant attractant such as a fungicide. It is noted that it is not possible to predict whether the solid state of a compound can exist as two or more polymorphs, nor to predict the properties of any of these crystalline forms.

[0017] The assay of the solid phase for the presence of crystals can be carried out by conventional methods known in the art. For example, it is convenient and usual to use powder X-ray diffraction techniques. Other techniques that can be used include differential scanning calorimetry (DSC), near-infrared spectroscopy, mid-infrared spectroscopy, nuclear magnetic resonance (NMR), gas chromatography or high performance liquid chromatography (HPLC). Single crystal X-ray diffraction is particularly useful for identifying crystal structures.

[0018] Another object of the present invention is a method for preparing a crystalline polymorph of a compound of formula I, comprising the following steps: i. mixing an industrial compound of formula I with an organic solvent at a temperature of at least 30 °C, more preferably at least 40 °C, to obtain a saturated solution of the industrial compound of formula I; ii. optionally, filtering the mixture obtained in step i; iii. crystallizing the compound obtained in step ii at a temperature below 30 °C, preferably at most 25 °C, to obtain a suspension; and iv. storing the suspension obtained in step iii at a temperature below 30 °C, preferably at most 25 °C, preferably for at least 2 hours, preferably for at least 4 hours, preferably for at least 10 hours, preferably for at least 15 days, more preferably for at least 30 days, to obtain a crystalline polymorph of the compound of formula I.

[0019] The industrial compound of formula I is a racemic mixture of a compound of formula I (3-difluoromethyl-1-methyl-1H-pyrazole-4-carboxylic acid (9-dichloromethylene-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl)-amide) having a purity of at least 98%, more preferably at least 99%, prepared as described in Example P11 of International Publication No. WO 2012 / 101139.

[0020] The organic solvent can be selected from xylene, isopropyl alcohol, chlorobenzene, acetone, methylcyclohexane, ethyl acetate, methanol, acetonitrile and any mixture thereof.

[0021] In step i, a saturated solution means that the solute (the compound of formula I) can no longer be dissolved in the solvent.

[0022] In step ii, the filtration step can help remove all remaining solid particles, such as undissolved solids, crystals, and / or dust. This optional step can limit or prevent nucleation points during the preparation method.

[0023] Step iv can advantageously be carried out with stirring, preferably with continuous stirring. The stirring can be gentle stirring, more specifically a constant gentle stirring. In the present invention, gentle stirring means stirring sufficient to suspend the solids.

[0024] After step iv, a filtration step v of the storage suspension can be carried out to isolate the crystals produced in step iv from their solvent and use them as solid seeds.

[0025] The polymorphs of the present invention can be applied in their as - is form, but more preferably can be incorporated into pesticidal compositions by conventional means. Accordingly, a further object of the present invention relates to a pesticidal composition comprising the crystalline polymorph defined by the present invention and at least one agriculturally acceptable carrier or diluent. The pesticidal composition containing the crystalline polymorph of the present invention can be used for controlling phytopathogenic fungi in several plant species.

[0026] Another object of the present invention relates to a method for preventing or controlling fungal infections on plants or plant propagation materials, which comprises treating the plants or plant propagation materials with the pesticidal composition, preferably with a fungicidally effective amount of the pesticidal composition.

[0027] The term "plant" refers to all physical parts of a plant, including seeds, seedlings, saplings, roots, tubers, stems, petioles, foliage, and fruits.

[0028] The term "plant propagation material" represents all the reproductive parts of plants such as seeds that can be used for their propagation, and is understood to represent vegetative plant material such as cuttings. Plant propagation materials include seeds (in the strict sense), roots, fruits, tubers, bulbs, rhizomes, and parts of plants. Also included are germinated plants and young shoots that are to be transplanted after germination or after emerging from the soil. These young shoots can be protected by complete or partial treatment by immersion before transplantation. The plant propagation material can be treated with the composition of the present invention before the material is sown or planted. Alternatively, the plant propagation material may be treated with the composition of the present invention during sowing or planting. Further, the composition of the present invention may be applied to previously treated propagation material before or during its planting. The composition of the present invention can be applied during the sowing of seeds. The composition can also be used for plant propagation materials derived from plants cultivated in a greenhouse and / or during transplantation.

[0029] More preferably, the plant propagation material is a seed. Seed treatment may be carried out on the seeds before sowing, and the term "seeds before sowing" means seeds during any period from the harvest of the seeds to the sowing of the seeds into the soil for the purpose of germination and plant growth. Treatment of the seeds before sowing does not mean an act of applying the composition to the soil, but includes any application act targeting the seeds during the sowing / planting process. The treated plant propagation material of the present invention can be treated in the same manner as conventional plant propagation materials. The treated propagation material can be stored, handled, sown, and cultivated in the same manner as other pesticide-treated materials.

[0030] The pesticidal composition of the present invention can be used, for example, to control phytopathogenic fungi belonging to the following classes: Ascomycetes (e.g., Venturia, Podosphaera, Erysiphe, Monilinia, Mycosphaerella, Uncinula); Basidiomycetes (e.g., Hemileia, Rhizoctonia, Phakopsora, Puccinia, Ustilago, Tilletia); Fungi imperfecti (also known as Deuteromycetes; e.g., Botrytis, Helminthosporium, Rhynchosporium, Fusarium, Septoria, Cercospora, Alternaria, Pyricularia, and Pseudocercosporella); Oomycetes (e.g., Phytophthora, Peronospora, Pseudoperonospora, Albugo, Bremia, Pythium, Pseudosclerospora, Plasmopara).

[0031] The pesticidal composition of the present invention is suitable for controlling such diseases in many plants and their propagation materials, including but not limited to the following target crops: cereals (wheat, barley, rye, oats, maize (including maize, popcorn, and sweet corn), rice, sorghum and related crops); beet (sugar beet and fodder beet); leguminous plants (beans, lentils, peas, soybeans); oil plants (rape, mustard, sunflower); cucurbitaceous plants (marrow, cucumber, melon); fiber plants (cotton, flax, hemp, jute); vegetables (spinach, lettuce, asparagus, cabbage, carrot, eggplant, onion, pepper, tomato, potato, paprika, okra); plantation crops (banana, fruit trees, rubber tree, forest land), ornamental plants (flowers, shrubs, broad-leaved and evergreen trees, for example conifers, etc.); and other plants, for example, grape, bushberry (such as blueberry, etc.), dogberry, cranberry, peppermint, rhubarb, spearmint, sugarcane and turfgrass, for example, but not limited to these, turfgrass in the cool season (for example, bluegrass (Poa L.), for example, Kentucky bluegrass (Poa pratensis L.), rough bluegrass (Poa trivialis L.), Canada bluegrass (Poa compressa L.), and annual bluegrass (Poa annua L.), etc.; bentgrass (Agrostis L.), for example creeping bentgrass (Agrostis palustris Huds.), colonial bentgrass (Agrostis tenius Sibth.), velvet bentgrass (Agrostis canina L.), and redtop (Agrostis alba L.); fescue (Festuca L.), for example tall fescue (Festuca arundinacea Schreb.), meadow fescue (Festuca elatior L.) and fine fescues, such as creeping red fescue (Festuca rubra L.), chewing fescue (Festuca rubra var. commutata Gaud.), sheep fescue (Festuca ovina L.), and hard fescue (Festuca longifolia); and ryegrass (Lolium L.), such as perennial ryegrass (Lolium perenne L.) and annual (Italian) ryegrass (Lolium multiflorum Lam.) and warm-season turfgrasses (e.g., Bermudagrass (Cynodon L.C.Rich), e.g., hybrid and common Bermudagrass; zoysiagrass (Zoysia Willd.), St. Augustinegrass (Stenotaphrum secundatum (Walt.) Kuntze); and centipedegrass (Eremochloa ophiuroides (Munro.) Hack.).

[0032] Furthermore, "crop" should be understood to include crops that are resistant to pests and pesticides, including herbicides or classes of herbicides, as a result of conventional methods of breeding or genetic engineering. For example, resistance to a herbicide means being less susceptible to damage caused by a particular herbicide compared to conventional crop varieties. Crops can be modified or crossed to be resistant to, for example, HPPD inhibitors such as mesotrione or EPSPS inhibitors such as glyphosate.

[0033] In particular, the compositions according to the invention are particularly effective against powdery mildew; rust; spot species; early leaves and mold; in particular Septoria, Puccinia, Erysiphe, Pyrenophora and Tapesia in cereals; Phakopsora in soybeans; Hemileia in coffee; Phragmidium in roses; Alternaria in potatoes, tomatoes and cucurbits; Sclerotinia in lawns, vegetables, sunflowers and crucifers; black rot, downy mildew, powdery mildew, gray mold and blight in grapes; Botrytis cinerea in fruits; Monilinia species of fruits and Penicillium species of fruits.

[0034] The composition according to the present invention is Alternaria spp., Ascochyta spp., Botrytis cinerea, Cercospora spp., Claviceps purpurea, Cochliobolus sativus, Colletotrichum spp., Epicoccum spp., Fusarium graminearum, Fusarium moniliforme, Fusarium oxysporum, Fusarium proliferatum, Fusarium solani, Fusarium subglutinans, Gaeumannomyces graminis, Helminthosporium spp., Microdochium nivale, Phoma spp., Pyrenophora graminea, Pyricularia oryzae, Rhizoctonia solani, Rhizoctonia cerealis, Sclerotinia spp., Septoria spp., Sphacelotheca reilliana, Tilletia spp., Typhula incarnata, Urocystis occulta, Ustilago spp. or Verticillium spp.against seed-borne and soil-borne diseases, such as; particularly for cereals such as wheat, barley, rye or triticale; maize; rice; cotton; soybeans; lawn; sugar beet; oilseed rape; potato; legumes such as pea, lentil or chickpea; and is even more particularly effective against pathogens of sunflowers.

[0035] The composition according to the invention is particularly effective against post-harvest diseases such as Botrytis cinerea, Colletotrichum musae, Curvularia lunata, Fusarium semitecum, Geotrichum candidum, Monilinia fructicola, Monilinia fructigena, Monilinia laxa, Mucor piriformis, Penicilium italicum, Penicilium solitum, Penicillium digitatum or Penicillium expansum, for example for pomaceous fruits such as apples and pears, stone fruits such as peaches and nectarines, citrus fruits, melons, papayas, kiwis, mangoes, soft fruits such as strawberries, avocados, pomegranates and bananas, and is even more particularly effective against pathogens of nuts.

[0036] The compositions according to the invention are particularly useful for controlling the following diseases on the following crops: Alternaria species on fruit and vegetables; Ascochyta species on pulse crops; Botrytis cinerea on strawberry, tomato, sunflower, pulse crops, vegetables and grapevine, for example Botrytis cinerea on grapevine; Cercospora arachidicola on peanut; Cochliobolus sativus on cereals; Colletotrichum species on pulse crops; Erysiphe species on cereals; for example, Erysiphe graminis on wheat, Erysiphe graminis and Erysiphe cichoracearum on barley and Sphaerotheca fuliginea; Fusarium species on cereals and maize; Gaumannomyces graminis on cereals and turf; Helminthosporium species on maize, rice and potato; Hemileia vastatrix on coffee; Microdochium species on wheat and rye; Mycosphaerella fijiensis on banana; Phakopsora species on soybean, for example Phakopsora pachyrizi on soybean; Puccinia species on cereals, broadleaf crops and perennials; for example, Puccinia recondita on wheat, Puccinia striiformis on wheat and Puccinia recondita on barley;Pseudocercosporella species in cereals, such as Pseudocercosporella herpotrichoides in wheat; Phragmidium mucronatum in roses; Podosphaera species in fruits; Pyrenophora species in barley, such as Pyrenophora teres in barley; Pyricularia oryzae in rice; Ramularia collo-cygni in barley; Rhizoctonia species in cotton, soybeans, cereals, maize, potatoes, rice and turf, such as Rhizoctonia solani on potatoes, rice, turf and cotton; Rhynchosporium secalis in barley, Rhynchosporium secalis in rye; Sclerotinia species in turf, lettuce, vegetables and oilseed rape, such as Sclerotinia sclerotiorum in oilseed rape and Sclerotinia homeocarpa in turf; Septoria species in cereals, soybeans and vegetables, such as Septoria tritici in wheat, Septoria nodorum on wheat and Septoria glycines in soybeans; Sphacelotheca reilliana in maize; Tilletia species in cereals; Uncinula necator, Guignardia bidwellii and Phomopsis viticola in grapes;Urocystis occulta in rye; Uromyces species in beans; Ustilago species in cereals and corn; Venturia species in fruits, e.g., Venturia inequalis in apples; Monilinia species in fruits; Penicillium species in citrus fruits and apples.

[0037] The rate of application of the agrochemical composition of the present invention is determined by factors such as the specific type of fungus to be controlled, the degree of control required, and the timing and method of application, and can be easily determined by those skilled in the art. Generally, the composition of the present invention can be applied at a rate of 0.005 kilograms per hectare (kg / ha) to about 5.0 kg / ha, based on the total amount of the active fungicide in the composition. A rate of about 0.1 kg / ha to about 1.5 kg / ha is preferred, and a rate of about 0.3 kg / ha to 0.8 kg / ha is particularly preferred.

[0038] In practice, the pesticidal composition containing the polymorph of the present invention is applied as a formulation containing various adjuvants and carriers known or used in the art. Thus, they can be formulated as controlled release forms such as granules, wettable powders, emulsifiable concentrates, suspension concentrates (including oil dispersions), dusts or powders, flowables, solutions, suspensions or emulsions, suspoemulsions or microcapsules. Suitably, the pesticidal composition of the present invention can be formulated as a suspension concentrate, suspoemulsion, emulsion concentrate or wet granulate. These formulations are described in more detail below and can contain from about 0.5% to about 95% or more of the active ingredient in polymorphic form. The optimum amount depends on the formulation of the phytopathogenic fungus to be controlled, the application equipment and the nature thereof.

[0039] Wettable powders are in the form of micronized particles that are easily dispersed in water or other liquid carriers. The particles contain the active ingredient held in a solid matrix. Typical solid matrices include fuller's earth, kaolin clay, silica, and other hygroscopic organic or inorganic solids. Wettable powders usually contain about 5% to about 95% by weight of the active ingredient and small amounts of wetting agents, dispersing agents, or emulsifiers.

[0040] Emulsifiable concentrates are homogeneous liquid compositions that are dispersible in water or other liquids and can consist only of the active compound and a liquid or solid emulsifier, or can also contain a liquid carrier such as xylene, high-boiling aromatic naphtha, isophorone, and other non-volatile organic solvents. In use, these concentrates are dispersed in water or other liquids and are usually applied as a spray to the area to be treated. The amount by weight of the active ingredient can range from about 0.5% to about 95% of the concentrate.

[0041] Suspension concentrates are formulations in which micronized solid particles of the active compound are stably suspended. The solid particles may be suspended in an aqueous solution or in oil (as an oil dispersion). Such formulations contain anti-settling agents and dispersing agents and may further contain wetting agents, defoaming agents, and crystal growth inhibitors to enhance activity. In use, these concentrates are diluted in water and are usually applied as a spray to the area to be treated. The amount by weight of the active ingredient can range from about 0.5% to about 95% of the concentrate.

[0042] The granular preparations contain both extrudates and relatively coarse particles and can be applied, for example, without the need for control of phytopathogenic fungi before application or without dilution in areas to be dispersed in the spray tank. Typical carriers for the granular formulations include sand, fuller's earth, attapulgite clay, bentonite clay, montmorillonite clay, vermiculite, perlite, calcium carbonate, bricks, pumice, phyllosilicate, kaolin, dolomite, gypsum, wood flour, ground corn cobs, ground peanut hulls, sugar, sodium chloride, sodium sulfate, sodium silicate, sodium borate, magnesia, mica, iron oxide, zinc oxide, titanium oxide, antimony oxide, cryolite, gypsum, diatomaceous earth, calcium sulfate and other organic or inorganic materials which can absorb the active compound or be coated with the active compound. Granular preparations for use without dilution usually contain from about 5% to about 25% by weight of the active ingredient, which may include heavy aromatic naphtha, kerosene and other petroleum fractions, or vegetable oils; and / or surfactants such as dextrin, adhesives or synthetic resins as adhesives. When the granules are to be dispersed in the spray tank before application, the active ingredient content can be increased up to 80% by weight.

[0043] Dusts are free-flowing mixtures of the active ingredient with micronized solids such as talc, clay, powders and other organic and inorganic solids which act as dispersants and carriers.

[0044] Microcapsules are typically droplets or granules of an active ingredient encapsulated in an inert, porous shell that allows the encapsulated material to be released to the surroundings at a controlled rate. Encapsulated droplets typically have a diameter of about 1 to about 50 microns. The encapsulated liquid typically constitutes about 50 to 95% of the weight of the capsule and may contain a solvent in addition to the active compound. Encapsulated granules are generally porous granules having a porous membrane that seals the pore openings of the granules to retain the active species in liquid form within the pores of the granules. The granules typically range in diameter from 1 millimeter to 1 centimeter, preferably from 1 to 2 millimeters. The granules are formed by extrusion, aggregation or prilling, or are natural. Examples of such materials are vermiculite, fired clay, kaolin, attapulgite clay, sawdust and granular carbon. Shell or membrane materials include natural and synthetic rubbers, cellulosic materials, styrene-butadiene copolymers, polyacrylonitrile, polyacrylate, polyester, polyamide, polyureas, polyurethanes and starch xanthates.

[0045] Other useful formulations for pesticidal applications include merely solutions of the active ingredient in a solvent that completely dissolves at the desired concentration, such as acetone, alkylated naphthalenes, xylene and other organic solvents. Pressurized sprayers in which the active ingredient is dispersed in a micronized form as a result of the evaporation of a low-boiling dispersant solvent carrier may also be used.

[0046] Many of the above formulations contain wetting agents, dispersing agents or emulsifying agents. Examples are alkyl sulfonates and alkyl aryl sulfonates and sulfates and their salts, polyhydric alcohols; polyethoxylated alcohols, esters and fatty amines. These agents, when used, usually constitute 0.1% to 40% (by weight) of the formulation.

[0047] Suitable agricultural adjuvants and carriers useful for formulating the compositions of the present invention of the above formulation types are well known to those skilled in the art. Suitable examples of different classes are found in the following non-limiting list.

[0048] Liquid carriers that can be used include water and any solvent in which the polymorph has no solubility or limited solubility, such as toluene, xylene, petroleum naphtha, crop oil, acetone, methyl ethyl ketone, cyclohexanone, acetic anhydride, acetonitrile, acetophenone, amyl acetate, 2-butanone, chlorobenzene, cyclohexane, cyclohexanol, alkyl acetate, diacetone alcohol, 1,2-dichloropropane, diethanolamine, p-diethylbenzene, diethylene glycol, diethylene glycol abietate, diethylene glycol butyl ether, diethylene glycol ethyl ether, diethylene glycol methyl ether, N,N-dimethylformamide, dimethyl sulfoxide, 1,4-dioxane, dipropylene glycol, dipropylene glycol methyl ether, dipropylene glycol dibenzoate, dipropitol, alkyl pyrrolidinone, ethyl acetate, 2-ethylhexanol, ethylene carbonate, 1,1,1-Trichloroethane, 2-heptanone, d-limonene, ethylene glycol, ethylene glycol butyl ether, ethylene glycol methyl ether, gamma-butyrolactone, glycerol, glycerol diacetate, glycerol monoacetate, glycerol triacetate, hexadecane, hexylene glycol, isoamyl acetate, isobornyl acetate, isooctane, isophorone, isopropylbenzene, isopropyl myristate, lactic acid, laurylamine, mesityl oxide, methoxypropanol, methyl isoamyl ketone, methyl isobutyl ketone, methyl laurate, methyl octanoate, methyl oleate, methylene chloride, m-xylene, n-hexane, n-octylamine, octadecanoic acid, octylamine acetate, oleic acid, oleylamine, o-xylene, phenol, polyethylene glycol (PEG400), propionic acid, propylene glycol, propylene glycol monomethyl ether, p-xylene, toluene, triethyl phosphate, triethylene glycol, xylene sulfonic acid, paraffin, mineral oil, trichloroethylene, perchloroethylene, ethyl acetate, amyl acetate, butyl acetate, methanol, ethanol, isopropanol, and amyl alcohol, tetrahydrofurfuryl alcohol, hexanol, octanol, ethylene glycol, propylene glycol, glycerin, N-methyl-2-pyrrolidinone and other high molecular weight alcohols may be mentioned. Water is generally the optimal carrier for dilution of the concentrate.,

[0049] Suitable solid carriers include talc, titanium dioxide, phyllosilicate clay, silica, attapulgite clay, kieselguhr, chalk, diatomaceous earth, lime, calcium carbonate, bentonite clay, fuller's earth, cottonseed hulls, wheat flour, soybean flour, pumice, wood flour, walnut shell powder and lignin, etc.

[0050] A wide range of surfactants are advantageously used in both the liquid and solid compositions, particularly those designed to be diluted with a carrier prior to application. The surfactant can be anionic, cationic, nonionic or polymeric in nature and can be used as an emulsifier, wetting agent, suspending agent or for other purposes. Typical surfactants include alkyl sulfates such as diethanolammonium lauryl sulfate; alkylaryl sulfonates such as calcium dodecylbenzenesulfonate; alkylphenol-alkylene oxide adducts such as nonylphenol-C.sub.18 ethoxylate; alcohol-alkylene oxide adducts such as tridecyl alcohol-C.sub.16 ethoxylate; soaps such as sodium stearate; alkylnaphthalene sulfonates such as sodium dibutylnaphthalenesulfonate; dialkyl esters of sulfosuccinate such as sodium di(2-ethylhexyl)sulfosuccinate; sorbitol esters such as sorbitol oleate; quaternary amines such as lauryltrimethylammonium chloride; polyethylene glycol esters of fatty acids such as polyethylene glycol stearate; block copolymers of ethylene oxide and propylene oxide; and salts of mono- and dialkyl phosphate esters.

[0051] Other adjuvants commonly used in agricultural compositions include crystallization inhibitors, viscosity modifiers, suspending agents, spray droplet regulators, pigments, antioxidants, foaming agents, defoaming agents, light blockers, solubilizers, sequestering agents, neutralizing agents and buffers, corrosion inhibitors, dyes, odorants, spreading agents, penetration aids, micronutrients, conditioners, lubricants and sticking agents.

[0052] Each of the above formulations can be prepared as a package containing a fungicide together with other components of the formulation (diluent, emulsifier, surfactant, etc.). The formulation can also be prepared by the tank mix method, where the components are obtained separately and combined at the grower's site.

[0053] These formulations can be applied, by conventional methods, to the areas where control is desired. For example, dusts and liquid compositions can be applied by the use of power dusters, brooms, hand-held sprayers and spray dusters. The formulations can also be applied as dusts or sprays from airplanes or by wick application. Both solid and liquid formulations can also be applied to the soil in the habitat of the plants to be treated, allowing the active ingredient to penetrate the plants through the roots. The formulations of the present invention can also be used for film coating application on plant propagation materials, achieving protection against fungal infections on plant propagation materials and against phytopathogenic fungi occurring in the soil. Preferably, the active ingredient can be applied to the plant propagation materials, especially seeds, so as to be protected by impregnating them with a fungicidal liquid formulation or coating them with a solid formulation. In special cases, other types of application, for example, specific treatment of plant cuttings or twigs that serve for propagation are also possible.

[0054] Suitably, the agrochemical compositions and formulations of the present invention are applied before the occurrence of the disease. The rates and frequencies of use of the formulations are those conventionally used in the art and are determined by the risk of infestation by fungal pathogens.

[0055] The compositions and formulations of the present invention can also be used in combination with other active ingredients (Compound II), such as other fungicides and / or insecticides and / or acaricides and / or nematicides and / or mollusks and / or biological agents and / or plant growth regulators. Such mixtures, and the use of such mixtures for controlling weeds and / or unwanted plant growth, form a further aspect of the present invention.

[0056] The following mixtures of the compound of formula I and the active ingredient (Compound II) are preferred: Auxiliaries selected from the group of substances consisting of petroleum (alternative name) (628); Abamectin, Acequinocyl, Acetamiprid, Acetoprole, Acrinathrin, Acinonapyr, Affidopyropen, Afoxolaner, Alanicarb, Allethrin, Alpha-cypermethrin, Alpha-methrin, Amidoflumet, Aminocarb, Azocyclotin, Bensultap, Benzoximate, Benzopyrimoxan, Betacyfluthrin, Beta-cypermethrin, Bifenazate, Bifenthrin, Binapacryl, Bioallethrin, S-Bioallethrin, Bioresthmetrin, Bistrifluron, Broflanilide, Brofluthrinate, Bromophos-ethyl, Buprofezin, Butocarboxim, Kazusaphos, Carbaryl, Carbofuran, Cartap, CAS No. 1632218-00-8, CAS No.: 1808115-49-2, CAS No.: 2032403-97-5, CAS No.: 2044701-44-0, CAS No.: 2128706-05-6, CAS No.: 2095470-94-1, CAS No.: 2377084-09-6, CAS No.: 1445683-71-5, CAS No.: 2408220-94-8, CAS No.: 2408220-91-5, CAS No.: 1365070-72-9, CAS No.: 2171099-09-3, CAS No.: 2396747-83-2, CAS No.: 2133042-31-4, CAS No.: 2133042-44-9, CAS No.: 1445684-82-1, CAS No.: 1922957-45-6, CAS No.: 1922957-46-7, CAS No.: 1922957-47-8, CAS No.: 1922957-48-9, CAS No.: 2415706-16-8, CAS No.: 1594624-87-9, CAS No.: 1594637-65-6, CAS No.: 1594626-19-3, CAS No.: 1990457-52-7, CAS No.: 1990457-55-0, CAS No.: 1990457-57-2, CAS No.: 1990457-77-6, CAS No.: 1990457-66-3, CAS No.: 1990457-85-6, CAS No.: 2220132-55-6, CAS No.: 1255091-74-7, CAS No.: RNA (Leptinotarsa decemlineata specific recombinant double-stranded interference GS2), CAS No.: 2719848-60-7,CAS No.: 1956329-03-5, Chlorantraniliprole, Chlordane, Chlorfenapyr, Chlorpropetrin, Chromafenozide, Clethodim, Cloethocarb, Clothianidin, 2-Chlorophenyl N-methylcarbamate (CPMC), Cyanofenphos, Cyantraniliprole, Cyclaniliprole, Cyclobutrifluram, Cycloprothrin, Cycloxaprid, Cyenopyrafen, Cyetpyrafen (or Ethipyrifluofen), Cyflumetofen, Cyfluthrin, Cyhalodiamide, Cyhalothrin, Cypermethrin, Cyphenothrin, Cyproflanilide, Cyromazine, Deltamethrin, Diafenthiuron, Diazinon, Dibrom, Dichloromethiaz, Diflubenzuron, Dipropylidaz, Dinactin, Dinocap, Dinotefuran, Dioxabenzofos, Emamectin (or Emamectin Benzoate), Empenthrin, Epsilon-Monofluorothrin, Epsilon-Methofluthrin, Esfenvalerate, Ethion, Ethiprole, Etofenprox, Ethoxazole, Fenthion, Fenazaquin, Fenfluthrin, Fenitrothion, Fenmezodithiaz, Phenothiocarb, Phenoxycarb, Fenpropathrin, Fenpyroximate, Fensulphothion, Fenthion, Fentin Acetate, Fenvalerate, Fipronil, Flometoquin, Flonicamid, Fluacrypyrim, Fluazaindolizine, Fluazuron, Flubendiamide, Flubendimine, Flucycloxuron, Flucythrinate, Flucycloxuron, Fluensulfone, Flufenoxuron, Flufenprox, Flufluprole, Flufenhexathion, Flumethrin, Fluopyram, Flupentiofenox, Flupyradifurone, Fluopyroxystrobin, Fluopyrim, Fluralaner, Flubutinate, Fluxametamide, fosthiazate, Gamma-Cyhalothrin, Guazatine, Halofenozide, Halfenprox, Heptafluthrin, Hexythiazox, Hydramethylnon, Imicyafos, Imidacloprid, Imiprothrin, Indazapyrroxamet, Indoxacarb, Iodomethane, Iprodione, Isocycloseram, Isothioate, Ivermectin, Kappa-Bifenthrin, Kappa-Tefluthrin,Lambda-cyhalothrin, spinosad, lepimectin, lotilaner, lufenuron, metaflumizone, metaaldehyde, metam, methomyl, methoxyphenozide, metofluthrin, methiocarb, mexacarbate, milbemectin, momfluorothrin, niclosamide, nifluprole, nitenpyram, nithiazine, omethoate, oxamyl, oxazosulfyl, parathion-ethyl, permethrin, phenothrin, phosphocarb, piperonyl butoxide, pyrimicarb, pyrimiphos-ethyl, pyrimiphos-methyl, polyhedrosis virus, prallethrin, profenofos, profluthrin, propargite, propaphos, propoxur, prothiofos, protriofenbut, pyflubumide, pymetrozine, pyraclofos, pyrafluprole, pyridaben, pyridalyl, pyrifluquinazon, pyrimidifen, pyriminostrobin, pyriprole, pyriproxyfen, resmethrin, sarolaner, selamectin, silafluofen, spinetoram, spinosad, spirodiclofen, spirohexafne, spirotetramat, spidoxamat, sulfoxaflor, tebufenozide, tebufenpyrad, tebupirimfos, tefluthrin, temephos, tetrachlorantraniliprole, tetradifon, tetramethrin, tetramethylfluthrin, tetranactin, tetraniliprole, theta-cypermethrin, thiacloprid, thiamethoxam, thiosyclam, thiodicarb, thiafenthoxam, thiofanox, thiofenton, thiosultap, tigilaner, thiorantraniliprole, thioxazafen, tolfenpyrad, toxaphene, tralomethrin, transfluthrin, triazamate, triazophos, trichlorfon, trichloronate, trichlorfon, triflumezone, triflumizopyrim, tyriazofluprole, zeta-cypermethrin, extracts of fermented products derived from seaweed and molasses, such as urea, amino acids, potassium, molybdenum and EDTA chelated manganese, extracts of seaweed and fermented plant products, extracts of seaweed and fermented plant products, such as, plant hormones, vitamins, EDTA chelated copper, zinc and iron, azadirachtin, Bacillus aizawai,Bacillus chitinosporus AQ746 (NRRL accession number B-21618), Bacillus firmus, Bacillus kurstaki, Bacillus mycoides AQ726 (NRRL accession number B-21664), Bacillus pumilus (NRRL accession number B-30087), Bacillus pumilus AQ717 (NRRL accession number B-21662), Bacillus sp. AQ178 (ATCC accession number 53522), Bacillus sp. AQ175 (ATCC accession number 55608), Bacillus sp. AQ177 (ATCC accession number 55609), unidentifiable Bacillus subtilis, Bacillus subtilis AQ153 (ATCC accession number 55614), Bacillus subtilis AQ30002 (NRRL accession number B-50421), Bacillus subtilis AQ30004 (NRRL accession number B-50455), Bacillus subtilis AQ713 (NRRL accession number B-21661), Bacillus subtilis AQ743 (NRRL accession number B-21665), Bacillus thuringiensis AQ52 (NRRL accession number B-21619), Bacillus thuringiensis BD#32 (NRRL accession number B-21530), Bacillus thuringiensis subspec. kurstaki BMP 123, Beauveria bassiana, D-limonene, granulovirus, Harpin,Helicoverpa armigera nucleopolyhedrovirus, Helicoverpa zea nucleopolyhedrovirus, Heliothis virescens nucleopolyhedrovirus, Heliothis punctigera nucleopolyhedrovirus, Metarhizium spp., Muscodor albus 620 (NRRL accession number B-30547), Muscodor roseus A3-5 (NRRL accession number 30548), neem tree-based products, Paecilomyces fumosoroseus, Paecilomyces lilacinus, Pasteuria nishizawae, Pasteuria penetramosa, Pasteuria thornei, Pasteuria usgae, P-sign, Plutella xylostella Granulosis virus, Plutella xylostella nucleopolyhedrovirus, polyhedrosis virus, pyrethrum, QRD 420 (terpenoid blend), QRD 452 (terpenoid blend), QRD 460 (terpenoid blend), Quillaja saponaria, Rhodococcus globerulus AQ719 (NRRL accession number B-21663), Spodoptera frugiperda nucleopolyhedrovirus, Streptomyces galbus (NRRL accession number 30232), Streptomyces sp. (NRRL accession number 30145), terpenoid blendan insect control active substance selected from the group consisting of Verticillium spp.;

[0057] an algicide selected from the group consisting of bitoxazin [CCN], copper dioctanoate (IUPAC name) (170), copper sulfate (172), sibuthrin [CCN], dichloron (1052), dichlorophene (232), endothal (295), fentin (347), slaked lime [CCN], nabam (566), chinomethionat (714), chinamide (1379), simazine (730), triphenyltin acetate (IUPAC name) (347), and triphenyltin hydroxide (IUPAC name) (347);

[0058] a vermifuge selected from the group consisting of abamectin (1), curdlanate (1011), doramectin (alternative name) [CCN], emamectin (291), emamectin benzoate (291), eprinomectin (alternative name) [CCN], ivermectin (alternative name) [CCN], milbemycin oxime (alternative name) [CCN]+, moxidectin (alternative name) [CCN], piperazine [CCN], selamectin (alternative name) [CCN], spinosad (737), and thiophanate (1435);

[0059] a bird killer selected from the group consisting of chloralose (127), endrin (1122), fenithion (346), pyridin-4-amine (IUPAC name) (23), and strychnine (745);

[0060] A fungicide selected from the group of substances consisting of 1-hydroxy-1H-pyridine-2-thione (IUPAC name) (1222), 4-(quinoxalin-2-ylamino)benzenesulfonamide (IUPAC name) (748), 8-hydroxyquinoline sulfate (446), bronopol (97), copper dioctanoate (IUPAC name) (170), copper hydroxide (IUPAC name) (169), cresol [CCN], dichlorophene (232), dipyrithione (1105), dodine (1112), fenaminosulf (1144), formaldehyde (404), hydralgafen (alternative name) [CCN], kasugamycin (483), kasugamycin hydrochloride hydrate (483), nickel bis(dimethyldithiocarbamate) (IUPAC name) (1308), nitrapyrin (580), octhilinone (590), oxolinic acid (606), oxytetracycline (611), potassium hydroxyquinoline sulfate (446), probenazole (658), streptomycin (744), streptomycin sesquisulfate (744), tecnazene (766) and thimerosal (alternative name) [CCN];

[0061] Adoxophyes orana GV (Alternative name) (12), Agrobacterium radiobacter (Alternative name) (13), Amblyseius genus (Alternative name) (19), Anagrapha falcifera NPV (Alternative name) (28), Anagrus atomus (Alternative name) (29), Aphelinus abdominalis (Alternative name) (33), Aphidius colemani (Alternative name) (34), Aphidoletes aphidimyza (Alternative name) (35), Autographa californica NPV (Alternative name) (38), Bacillus firmus (Alternative name) (48), Bacillus sphaericus Neide (Scientific name) (49), Bacillus thuringiensis Berliner (Scientific name) (51), Bacillus thuringiensis var. aizawai (Scientific name) (51), Bacillus thuringiensis subsp. israelensis (Scientific name) (51), Bacillus thuringiensis subsp.japonensis (scientific name) (51), Bacillus thuringiensis subsp. kurstaki (scientific name) (51), Bacillus thuringiensis subsp. tenebrionis (scientific name) (51), Beauveria bassiana (alias) (53), Beauveria brongniartii (alias) (54), Chrysoperla carnea (alias) (151), Cryptolaemus montrouzieri (alias) (178), Cydia pomonella GV (alias) (191), Dacnusa sibirica (alias) (212), Diglyphus isaea (alias) (254), Encarsia formosa (scientific name) (293), Eretmocerus eremicus (alias) (300), Helicoverpa zea NPV (alias) (431), Heterorhabditis bacteriophora and H.Megidis (alias) (433), Hippodamia convergens (alternate name) (442), Leptomastix dactylopii (alternate name) (488), Macrolophus caliginosus (alias) (491), Mamestra brassicae NPV (alternate name) (494), Metaphycus helvolus (alternate name) (522), Metarhizium anisopliae var. acridum (scientific name) (523), Metarhizium anisopliae var. anisopliae (scientific name) (523), Neodiprion sertifer NPV and N.Biological agents selected from the group of substances consisting of Lecontei NPV (alias) (575), Orius genus (alias) (596), Paecilomyces fumosoroseus (alias) (613), Phytoseiulus persimilis (alias) (644), Spodoptera exigua multicapsid nucleopolyhedrovirus (scientific name) (741), Steinernema bibionis (alias) (742), Steinernema carpocapsae (alias) (742), Steinernema feltiae (alias) (742), Steinernema glaseri (alias) (742), Steinernema riobrave (742), Steinernema riobravis (alias) (742), Steinernema scapterisci (alias) (742), Steinernema genus (alias) (742), Trichogramma genus (alias) (826), Typhlodromus occidentalis (alias) (844) and Verticillium lecanii (alias) (848);

[0062] Soil sterilants selected from the group of substances consisting of iodomethane (IUPAC name) (542) and methyl bromide (537);

[0063] A chemical sterilizing agent selected from the group of substances consisting of aholeate [CCN], bisazil (alternative name) [CCN], busulfan (alternative name) [CCN], diflubenzuron (250), dimatiph (alternative name) [CCN], hemer [CCN], hempa [CCN], metepa [CCN], methiotepa [CCN], methyl aholeate [CCN], morgid [CCN], penfluron (alternative name) [CCN], tepa [CCN], thiohempa (alternative name) [CCN], thiotepa (alternative name) [CCN], tretamine (alternative name) [CCN], and uredepa (alternative name) [CCN];

[0064] (E)-Dec-5-en-1-yl acetate (IUPAC name) (222), (E)-Tridec-4-en-1-yl acetate (IUPAC name) (829), (E)-6-Methylhepta-2-en-4-ol (IUPAC name) (541), (E,Z)-Tetradec-4,10-dien-1-yl acetate (IUPAC name) (779), (Z)-Dodec-7-en-1-yl acetate (IUPAC name) (285), (Z)-Hexadec-11-enal (IUPAC name) (436), (Z)-Hexadec-11-en-1-yl acetate (IUPAC name) (437), (Z)-Hexadec-13-en-11-yn-1-yl acetate (IUPAC name) (438), (Z)-Icosa-13-en-10-one (IUPAC name) (448), (Z)-Tetradec-7-en-1-ol (IUPAC name) (782), (Z)-Tetradec-9-en-1-ol (IUPAC name) (783), (Z)-Tetradec-9-en-1-yl acetate (IUPAC name) (784), (7E,9Z)-Dodec-7,9-dien-1-yl acetate (IUPAC name) (283), (9Z,11E)-Tetradec-9,11-dien-1-yl acetate (IUPAC name) (780), (9Z,12E)-Tetradec-9,12-dien-1-yl acetate (IUPAC name) (781), 14-Methyloctadec-1-ene (IUPAC name) (545), 4-Methylnonan-5-ol and 4-Methylnonan-5-one (IUPAC name) (544), Alpha-multistriatin (alternative name) [CCN], Brevicomin (alternative name) [CCN], Codlelure (alternative name) [CCN], Codlemone (alternative name) (167), Cuelure (alternative name) (179), Dispellure (277), Dodec-8-en-1-yl acetate (IUPAC name) (286), Dodec-9-en-1-yl acetate (IUPAC name) (287), Dodec-8,10-dien-1-yl acetate (IUPAC name) (284), Dominicalure (alternative name) [CCN], Ethyl 4-methyloctanoate (IUPAC name) (317), Eugenol (alternative name) [CCN], Frontalin (alternative name) [CCN], Gossyplure (registered trademark) (alternative name;A 1:1 mixture of the (Z,E) and (Z,Z) isomers of hexadeca-7,11-dien-1-yl acetate (420), granulure (421), granulure I (alternative name) (421), granulure II (alternative name) (421), granulure III (alternative name) (421), granulure IV (alternative name) (421), hexalure [CCN], ipsdienol (alternative name) [CCN], ipsenol (alternative name) [CCN], japonilure (alternative name) (481), lineratin (alternative name) [CCN], litlure (alternative name) [CCN], looplure [CCN], megulure [CCN], megaatomic acid (alternative name) [CCN], methyleugenol (alternative name) (540), muscalure (563), octadeca-2,13-dien-1-yl acetate (IUPAC name) (588), octadeca-3,13-dien-1-yl acetate (IUPAC name) (589), orfralure (alternative name) [CCN], orictalure (alternative name) (317), ostramone (alternative name) [CCN], siglure [CCN], soldiudin (alternative name) (736), sulcatol (alternative name) [CCN], tetradeca-11-en-1-yl acetate (IUPAC name) (785), trimedlure (839), trimedlure A (alternative name) (839), trimedlure B1 (alternative name) (839), trimedlure B2 (839), trimedlure C (alternative name) (839) and trunc-call (alternative name) [CCN]; an insect pheromone selected from the group of substances consisting of

[0065] 2-(octylthio)ethanol (IUPAC name) (591), butapironexyl (933), butoxy(polypropylene glycol) (936), dibutyl adipate (IUPAC name) (1046), dibutyl phthalate (1047), dibutyl succinate (IUPAC name) (1048), diethyltoluamide [CCN], dimethylcarbamate [CCN], dimethyl phthalate [CCN], ethylhexanediol (1137), hexamide [CCN], methokine-butyl (1276), methyl neodecanamide [CCN], oxamate [CCN] and picaridin [CCN]; an insect repellent selected from the group of substances consisting of

[0066] Bis(tributyltin) oxide (IUPAC name) (913), bromoacetamide [CCN], calcium arsenite [CCN], chlorethocarb (999), copper acetoarsenite [CCN], copper sulfate (172), fentin (347), ferric phosphate (IUPAC name) (352), metaaldehyde (518), methiocarb (530), niclosamide (576), niclosamide - olamine (576), pentachlorophenol (623), sodium pentachlorophenoxide (623), thiazinamcarb (1412), thiodicarb (799), tributyltin oxide (913), triphenyltin hydroxide (IUPAC name) (347), triphenyltin acetate (IUPAC name) (347), and a molluscicide selected from the group consisting of pyriprole [394730 - 71 - 3];

[0067] AKD-3088 (Compound Code), 1,2-dibromo-3-chloropropane (IUPAC / Chemical Abstracts Name) (1045), 1,2-dichloropropane (IUPAC / Chemical Abstracts Name) (1062), 1,2-dichloropropane and 1,3-dichloropropene (IUPAC Name) (1063), 1,3-dichloropropene (233), 3,4-dichlorotetrahydrothiophene 1,1-dioxide (IUPAC / Chemical Abstracts Name) (1065), 3-(4-chlorophenyl)-5-methyl rhodanine (IUPAC Name) (980), 5-methyl-6-thioxo-1,3,5-thiadiazinan-3-yl acetic acid (IUPAC Name) (1286), 6-isopentenylaminopurine (Alternative Name) (210), abamectin (1), acetoprole [CCN], alanicarb (15), aldicarb (16), aldoxycarb (863), AZ60541 (compound code), Benclothiaz [CCN], Benomyl (62), Butylpyridaben (alias), Kazusaphos (109), Carbofuran (118), Carbon disulfide (945), Carbosulfan (119), Chloropicrin (141), Chlorpyrifos (145), Cloetocarb (999), Cytokinin (alias) (210), Dazomet (216), DBCP (1045), DCIP (218), Diamidafos (1044), Diclofenthion (1051), Diglyphos (alias), Dimethoate (262), Doramectin (alias) [CCN], Emamectin (291), Emamectin benzoate (291), Eprinomectin (alias) [CCN], Ethoprophos (312), Ethylene dibromide (316), Fenamiphos (326), Fenpyrazamine (alias), Fensulfothion (1158), Fosthiazate (408), Fosthietan (1196), Furfural (alias) [CCN], GY-81 (development code) (423), Heterophos [CCN], Iodomethane (IUPAC name) (542), Isamidafos (1230), Isazophos (1231), Ivermectin (alias) [CCN], Kinetin (alias) (210), Mekarphon (1258), Metam (519), Metacalium (alias) (519), Meta-sodium (519), Methyl bromide (537), Methyl isothiocyanate (543), Milbemycin oxime (alias) [CCN], Moxidectin (alias) [CCN], Myrothecium verrucaria composition (alias) (565), NC-184 (compound code), Oxamyl (602), Phorate (636), Phosphamidon (639), Phosphocarb [CCN], Cebuphos (alias), Selamectin (alias) [CCN], Spinosad (737), Turban (alias), Terbufos (773), Tetrachlorothiophene (IUPAC / Chemical Abstracts name) (1422), Thiafenox (alias), Thionazin (1434), Triazophos (820), Triazolone (alias), Xylenol [CCN], YI-5302 (compound code), Zeatin (alias) (210), Fluenesulfone [318290-98-1], Fluopyram, nematicides selected from the group consisting of;

[0068] A nitrification inhibitor selected from the group of substances consisting of potassium ethylxanthate [CCN] and nitrapyrin (580);

[0069] A plant activator selected from the group of substances consisting of acibenzolar (6), acibenzolar-S-methyl (6), probenazole (658) and an extract of giant knotweed (Reynoutria sachalinensis) (alternative name) (720);

[0070] A rodenticide selected from the group of substances consisting of 2-isovalerylindane-1,3-dione (IUPAC name) (1246), 4-(quinoxalin-2-ylamino)benzenesulfonamide (IUPAC name) (748), alpha-chlorohydrin [CCN], aluminum phosphide (640), anto (880), arsenic oxide (882), barium carbonate (891), bistiosemi (912), brodifacoum (89), bromadiolone (or alpha-bromadiolone), bromethalin (92), calcium cyanide (444), chloralose (127), chlorophacinone (140), cholecalciferol (alias) (850), chlorol (1004), coumafural (1005), coumatetralyl (175), crimidine (1009), diphenacoum (246), diphacinone (249), difethialone (273), ergocalciferol (301), flocoumafen (357), fluoroacetamide (379), flupropazide (1183), flupropazide hydrochloride (1183), gamma-HCH (430), HCH (430), hydrogen cyanide (444), iodomethane (IUPAC name) (542), lindane (430), magnesium phosphide (IUPAC name) (640), methyl bromide (537), norbormide (1318), phosphoacetim (1336), phosphine (IUPAC name) (640), phosphorus [CCN], pindone (1341), potassium arsenite [CCN], pirinuron (1371), slidroside (1390), sodium arsenite [CCN], sodium cyanide (444), sodium fluoroacetate (735), strychnine (745), thallium sulfate [CCN], warfarin (851) and zinc phosphide (640);

[0071] A synergist selected from the group of substances consisting of 2-(2-butoxyethoxy)ethyl piperonate (IUPAC name) (934), 5-(1,3-benzodioxol-5-yl)-3-hexylcyclohex-2-enone (IUPAC name) (903), farnesol + nerolidol (alternative name) (324), MB-599 (development code) (498), MGK 264 (development code) (296), piperonyl butoxide (649), piprotal (1343), propyl isomer (1358), S421 (development code) (724), sesamethox (1393), sesasolin (1394) and sulfoxide (1406);

[0072] An animal repellent selected from the group of substances consisting of anthraquinone (32), chloralose (127), copper naphthenate [CCN], copper oxychloride (171), diazinon (227), dicyclopentadiene (chemical name) (1069), guazatine (422), guazatine acetate (422), methiocarb (530), pyridin-4-amine (IUPAC name) (23), thiram (804), trimethacarb (840), zinc naphthenate [CCN] and ziram (856);

[0073] An antiviral agent selected from the group of substances consisting of imanine (alternative name) [CCN] and ribavirin (alternative name) [CCN];

[0074] A wound protectant selected from the group of substances consisting of mercuric oxide (512), octylinone (590) and thiophanate-methyl (802); 1,1-Bis(4-chlorophenyl)-2-ethoxyethanol, 2,4-dichlorophenylbenzenesulfonate, 2-fluoro-N-methyl-N-1-naphthylacetamide, 4-chlorophenylphenylsulfone, aceprol, aldicarb, amidosulfotep, amidithioate, amiton, hydrogen oxalate amiton, amitraz, aramite, arsenic oxide, azobenzene, azothoate, benomyl, benoxaphos, benzyl benzoate, bixafen, brofenvalerate, bromocyclene, bromophos, bromopropylate, buprofezin, butocarboxim, butoxycarboxim, butylpyridaben, calcium polysulfide, camphechlor, carbaryl, carbophenothion, cymiazole, quinomethionate, chlorbenside, chlordimeform, chlordimeform hydrochloride, chlorphenethol, chlorfenson, chlorfensulfide, chlorobenzilate, chloromethiuron, chloropropylate, chlorothiophos, cinerythrin I, cinerythrin II, cinerythrin, chlorthal, coumaphos, chlorotoluron, chlorotoxyfos, cupravit, cyanothoate, DCPM, DDT, demephion, demephion-O, demephion-S, demeton-methyl, demeton-O, demeton-O-methyl, demeton-S, demeton-S-methyl, demeton-S-methyl sulfone, dichlofluanid, dichlorvos, dicriphos, dimethachlor, dimefox, dinex, dinocap-4, dinocap-6, dinocap, dinopenton, dinosulfon, dinoterbon, dioxathion, diphenyl sulfone, disulfiram, DNOC, dofenapyn, doramectin, endothion, eprinomectin, ethothionate-methyl, ethirimol, fenazaflor, fenbutatin oxide, phenothiocarb, fenpyrazamine, fenpyroximate, fenpyrazamine, fenson, fentrifanil, flubenzimine, flucycloxuron, fluenthyl, fluorethyl, FMC1137, formetanate, formetanate hydrochloride, formothion, gamma-HCH, gliotoxin, halfenprox, hexadecyl cyclopropanecarboxylate, isocarbophos, jasmonelin I, jasmonelin II,Jodfenphos, Lindane, Malonoben, Mecarbam, Methophora, Mesulfen, Methacriphos, Methyl bromide, Methomyl, Mexacarbate, Milbemycin oxime, Mipafox, Monocrotophos, Morphothion, Moxidectin, Naled, 4-Chloro 2-(2-chloro-2-methyl-propyl) 5-[(6-iodo-3-pyridyl)methoxy]pyridazin-3-one, Nifluridide, Nikkomycin, Nitrilacarb, Nitrilacarb 1:1 zinc chloride complex, Omethoate, Oxydeprofos, Oxydisulfoton, pp'-DDT, Parathion, Permethrin, Fencapton, Phosalone, Phosphoram, Phosphamidon, Polychloroterpene, Polynactin, Proclonol, Promacyl, Propoxur, Prothidathion, Prothoate, Pyrethrin I, Pyrethrin II, Pyrethrin, Pyridaphenthion, Pyrimidate, Quinalphos, Quincholphos, R-1492, Phosphoglycine, Rotenone, Schrader, Cephos, Selamectin, Sofamide, SSI121, Sulfiram, Sulfuramid, Sulfotepp, Sulfur, Diflubenzuron, Tau-fluvalinate, TEPP, Terbum, Tetradifon, Tetrasul, Thiafenox, Thiocarboxime, Thiofanox, Thimeton, Thioquinox, Thuringiensin, Triamiphos, Triarathene, Triazophos, Triazolone, Triphenox, Trinactin, Bamithion, Vaniliprole, Vetoxazine, Copper dioctanoate, Copper sulfate, Sibutramine, Dicloran, Dichlorophen, Endothal, Fentin, Hydrated lime, Nabam, Quinoclamine, Quinonamide, Simazine, Triphenyltin acetate, Triphenyltin hydroxide, Crufomate, Piperazine, Thiophanate, Chloralose, Fenthion, Pyridin-4-amine, Strychnine, 1-Hydroxy-1H-pyridine-2-thione, 4-(Quinoxalin-2-ylamino)benzenesulfonamide, 8-Hydroxyquinoline sulfate, Bronopol, Copper hydroxide, Cresol, Dipyrithione, Dodine, Phenaminosulf, Formaldehyde, Hydralazine, Kasugamycin, Kasugamycin hydrochloride hydrate, Nickel bis(dimethyldithiocarbamate), Nitrapyrin, Octilinone, Oxolinic acid, Oxytetracycline,Potassium hydroxyquinoline sulfate, probenazole, streptomycin, streptomycin sesquisulfate, tecnazene, thimerosal, Adoxophyes orana GV, Agrobacterium radiobacter, genus Amblyseius, Anagrapha falcifera NPV, Anagrus atomus, Aphelinus abdominalis, Aphidius colemani, Aphidoletes aphidimyza, Autographa californica NPV, Bacillus sphaericus Neide, Beauveria brongniartii, Chrysoperla carnea, Cryptolaemus montrouzieri, Cydia pomonella GV, Dacnusa sibirica, Diglyphus isaea, Encarsia formosa, Eretmocerus eremicus, Heterorhabditis bacteriophora and H. megidis, Hippodamia convergens, Leptomastix dactylopii, Macrolophus caliginosus, Mamestra brassicae NPV, Metaphycus helvolus,Metarhizium anisopliae var. acridum, Metarhizium anisopliae var. anisopliae, Neodiprion sertifer NPV and N. lecontei NPV, Orius genus, Paecilomyces fumosoroseus, Phytoseiulus persimilis, Steinernema bibionis, Steinernema carpocapsae, Steinernema feltiae, Steinernema glaseri, Steinernema riobrave, Steinernema riobravis, Steinernema scapterisci, Steinernema genus, Trichogramma genus, Typhlodromus occidentalis, Verticillium lecanii, apholate, bisazir, busulfan, dimethipin, hemer, hempa, metepa, methiotepa, methyl apholate, moldex, penfluron, tepa, thiohempa, thiotepa, tretamine, uredepa, (E)-dec-5-en-1-yl acetate and (E)-dec-5-en-1-ol, (E)-tridec-4-en-1-yl acetate, (E)-6-methylhepta-2-en-4-ol, (E,Z)-tetradeca-4,10-dien-1-yl acetate, (Z)-dodec-7-en-1-yl acetate, (Z)-hexadeca-11-enal, (Z)-hexadeca-11-en-1-yl acetate, (Z)-hexadeca-13-en-11-in-1-yl acetate, (Z)-icos-13-en-10-one(Z)-tetradec-7-en-1-ol, (Z)-tetradec-9-en-1-ol, (Z)-tetradec-9-en-1-yl acetate, (7E,9Z)-dodeca-7,9-dien-1-yl acetate, (9Z,11E)-tetradeca-9,11-dien-1-yl acetate, (9Z,12E)-tetradeca-9,12-dien-1-yl acetate, 14-methyloctadec-1-ene, 4-methylnonan-5-ol and 4-methylnonan-5-one, α-multistriatin, brevicomin, codrea, codlure, curculin, disparlure, dodec-8-en-1-yl acetate, dodec-9-en-1-yl acetate, dodeca-8,10-dien-1-yl acetate, dominicalure, ethyl 4-methyloctanoate, eugenol, frontalin, grandlure, grandlure I, grandlure II, grandlure III, grandlure IV, hexalure, ipsdienol, ipsenol, japonilure, linetin, littlelure, looplure, medlure, megatomonic acid, methyleugenol, muscalure, octadeca-2,13-dien-1-yl acetate, octadeca-3,13-dien-1-yl acetate, orfralure, oryctalure, ostramone, siglure, soldi-dine, sulcatol, tetradec-11-en-1-yl acetate, trimedlure, trimedlure A, trimedlure B1, trimedlure B2, trimedlure C, trunk-call, 2-(octylthio)ethanol, butopyronoxyl, butoxy(polypropylene glycol), dibutyl adipate, dibutyl phthalate, dibutyl succinate, N,N-diethyl-m-toluamide, dimethyl carboxylic acid, dimethyl phthalate, ethylhexanediol, hexamide, methoquin-butyl, methyl neodecanamide, oxamate, picaridin, 1,1-dichloro-1-nitroethane, 1,1-dichloro-2,2-bis(4-ethylphenyl)ethane, 1,2-dichloropropane and 1,3-dichloropropene, 1-bromo-2-chloroethane, 2,2,2-trichloro-1-(3,4-dichlorophenyl)ethyl acetate, 2,2-dichlorovinyl 2-ethylsulfinylethyl methyl phosphate,2-(1,3-dithiolan-2-yl)phenyl dimethylcarbamate, 2-(2-butoxyethoxy)ethyl thiocyanate, 2-(4,5-dimethyl-1,3-dioxolan-2-yl)phenyl methylcarbamate, 2-(4-chloro-3,5-xyloxy)ethanol, 2-chlorovinyl diethyl phosphate, 2-imidazolidone, 2-isovaleryl lindane-1,3-dione, 2-methyl(prop-2-ynyl)aminophenyl methylcarb, Mate, 2-thiocyanatoethyl laurate, 3-bromo-1-chloroprop-1-ene, 3-methyl-1-phenylpyrazol-5-yl dimethylcarbamate, 4-methyl(prop-2-ynyl)amino 3,5-xylyl methylcarbamate, 5,5-dimethyl 3-oxohex-1-enyl dimethylcarbamate, acetion, acrylonitrile, aldrin, allosamidin, alicarb, α-ecdysone, aluminium phosphide, aminocarb, anabasine, azamethiphos, Bacillus thuringiensis delta-endotoxin, barium hexafluorosilicate, barium polysulfide, barthrin, Bayer22 / 190, Bayer22408, beta-cyfluthrin, beta-cypermethrin, bioethanomethrin, bifenthrin, bis(2-chloroethyl) ether, borax, bromfenvinphos, bromo-DDT, bufencarb, butacarb, butathiophos, butonate, calcium arsenite, calcium cyanide, carbon disulfide, carbon tetrachloride, cartap hydrochloride, sevin, chlorbicyclen, chlordane, chlordecone, chloroform, chloropicrin, chlorfioxym, chlorprozophos, cis-resmethrin, cispermethrin, chlorthrin, copper acetarsenite, copper arsenate, copper oleate, cumithoate, cryolite, CS 708, cyanofenphos, cyanophos, cyclothrin, cythioate, d-tetramethrin, DAEP, dazomet, decarbofuran, diamidafos, dicapthon, dichlofenthion, dicresyl, dicyclanil, dieldrin, diethyl 5-methylpyrazol-3-yl phosphate, dicrotophos, dimefluthrin, dimethan, dimenthion, dimethylvinphos, dimethiran, dinoprop, dinosam, dinoseb, dioxabenzofos, dicrotophos, DSP, ecdysterone, EI1642, EMPC, EPBP, ethion, ethiofencarb, ethyl formate, ethylene dibromide, ethylene dichloride, ethylene oxide, EXD, fenchlorphos, fenethacarb, fenitrothion, phenoxacrim, fenpyrethrin, fenthion-ethyl, flucofuron, formothion, fosmethilan, fosthiazate, fosthietan, fluthiacarb,Fretelin, guazatine, guazatine acetate, sodium tetrathiolcarbonate, halfenprox, HCH, HEOD, heptachlor, heterophos, HHDN, hydrogen cyanide, hikicarbon, IPSP, isazophos, isobenzan, isodrin, isofenphos, isolan, isoprothiolane, isoxathion, juvenile hormone I, juvenile hormone II, juvenile hormone III, kerevan, kinoprene, lead arsenate, leptophos, liliumphos, lithidathion, M-cumenylmethylcarbamate, magnesium phosphide, magidox, mecarbofos, menazon, mercury chloride, mesulfenphos, metam, metam-potassium, metam-sodium, methanesulfonyl fluoride, methocrotophos, methoprene, methothrin, methoxychlor, isothiocyanate methyl, methyl chloroform, methylene chloride, methoxadiazone, mirex, naphthalophos, naphthalene, NC-170, nicotine, nicotine sulfate, nithiazine, nor-nicotine, O-5-dichloro-4,4-iodophenyl O-ethylphosphonothioate, O,O-diethyl O-4-methyl-2-oxo-2H-chromen-7-yl phosphorothioate, O,O-diethyl O-6-methyl-2-propylpyrimidin-4-yl phosphorothioate, O,O,O’,O’-tetrapropyl dithiopyrophosphate, oleic acid, para-dichlorobenzene, parathion-methyl, pentachlorophenol, pentachlorophenyl laurate, PH 60-38, phenapton, phosphonitril chloride, phosphine, hokxim-methyl, pirimiphos, polychlorodicyclopentadiene isomers, potassium arsenite, potassium thiocyanate, precocene I, precocene II, precocene III, primidophos, profluthrin, promecarb, prothiofos, pyrazophos, pyresmethrin, quassia, quinalphos-methyl, quinothion, rafoxanide, resmethrin, rotenone, cadethrin, ryania, ryanodine, sabadilla, schradan, sebufos, SI-0009, thiapronyl, sodium arsenite, sodium cyanide, sodium fluoride, sodium hexafluorosilicate, sodium pentachlorophenoxide, sodium selenate, sodium thiocyanate, sulprofos, sulprofos-sodium, sulfuryl fluoride, sulprophos, tar oil, tadimcarb, TDETebupirimfos, temephos, terallethrin, tetrachloroethane, chlorpyrifos, thicyclam, thicyclam hydrogen oxalate, thionazin, thiosultap, thiosultap-sodium, tralomethrin, transpermethrin, triazamate, trichlorfon-3, trichloronate, trimethacarb, tolprocarb, triclopyricarb, triprene, veratridine, veratrin, XMC, zetamethrin, zinc phosphide, zolaprofos, metofluthrin, tetramethylfluthrin, bis(tributyltin)oxide, bromoacetamide, ferric phosphate, niclosamide-olamine, tributyltin oxide, pyrimorph, trifenmorph, 1,2-dibromo-3-chloropropane, 1,3-dichloropropene, 3,4-dichlorotetrahydrothiophene 1,1-dioxide, 3-(4-chlorophenyl)-5-methyl rhodanine, 5-methyl-6-thioxo-1,3,5-thiadiazinan-3-yl acetic acid, 6-isopentenylaminopurine, anilofop-ethyl, benclothiaz, cytokinin, DCIP, furfural, isamidofos, kinetin, Myrothecium verrucaria composition, tetrachlorothiophene, xylenol, zeatin, potassium ethylxanthate, acibenzolar, acibenzolar-S-methyl, Reynoutria sachalinensis extract, α-chlorohydrin, anticoagulant, barium carbonate, bistiosemicarbazone, brodifacoum, bromadiolone, bromethalin, chlorophacinone, cholecalciferol, coumachlor, coumafuryl, coumatetralyl, cloridazine, diphenacoum, diphacinone, difenacoum, ergocalciferol, flocoumafen, fluoroacetamide, flupropazone, flupropazone hydrochloride, norbormide, hosethyl, phosphorus, pindone, pirinuron, silymarin, sodium fluoroacetate, potassium sulfate, warfarin, 2-(2-butoxyethoxy)ethyl piperonate, 5-(1,3-benzodioxol-5-yl)-3-hexylcyclohex-2-enone, farnesol and nerolidol, verbascoside, MGK264, piperonyl butoxide, piprotal, propyl isomer, S421,Sesamex, sesamolin, sulfoxide, anthraquinone, copper naphthenate, copper oxychloride, dicyclopentadiene, thiram, zinc naphthenate, dilan, imanin, ribavirin, chloroincanazide, mercury oxide, thiophanate-methyl, azaconazole, bitertanol, bromoconazole, cyproconazole, difenoconazole, diniconazole, epoxyconazole, fenbuconazole, fluquinconazole, flusilazole, flutriafol, flutriafol, flutriafol, hexaconazole, imazalil, imibenconazole, ipconazole, metconazole, myclobutanil, paclobutrazol, pefurazoate, penconazole, prothioconazole, pyrifenox, procraz, propiconazole, pyrisooxazole,simeconazole, tebuconazole, tetraconazole, triadimefon, triadimenol, triflumizole, triticonazole, ancymidol, fenarimol, nuarimol, bupirimate, dimethirimol, ethirimol, dodemorph, fenpropidin, fenpropimorph, spiroxamine, tridemorph, cyprodinil, mepanipyrim, pyrimethanil, fenpiclonil, fludioxonil, benalaxyl, furalaxyl, metalaxyl, R-metalaxyl, ofurace, oxadixyl, carbendazim, debacarb, fuberidazole, thiabendazole, chlorothalonil, dichlorozolin, microzolin, procymidone, vinclozolin, boscalid, carboxin, fenfluram, flutolanil, mepronil, oxycarboxin, penthiopyrad, thifluzamide, dodine, iminoctadine, azoxystrobin, dimoxystrobin, enestrobin, fenamidstrobin, fluopicoxystrobin, fluoxastrobin, kresoxim-methyl, metominostrobin, trifloxystrobin, orysastrobin, picoxystrobin, pyraclostrobin, pyra-metostrobin, pyraoxystrobin, ferbam, mancozeb, maneb, metiram, propineb, zineb, captan, Captain, Fluoroimide, Forpet, Trifluoride, Bordeaux mixture, Copper oxide, Mancozeb, Oxine-copper, Nitrotal-isopropyl, Edifenphos, Iprobenfos, Phosphodifen, Tolclofos-methyl, Anilazine, Benthiavalicarb, Blasticidin-S, Chloroneb, Chlorothalonil, Ciflufenamid, Simoxanil, Cyclobutrifluram, Diclocymet, Diclomezine, Dichloran, Diethofencarb, Dimethomorph, Flumorph, Dithianon, Ethaboxam, Ethridiazole, Famoxadone, Fenamidone, Phenoxanil, Ferimzone, Fluazinam, Flumezin, Fluopicolide, Fluoxastrobin, Flusulfamide, Fluoxapipoxad, Fenhexamid, Phosphorous acid, Hymexazol, Iprovalicarb, Cyazofamid, Metasulfocarb, Metrafenone, Penthiopyrad, Phthalide, Polyoxin, Propamocarb, Pyribencarb, Proquinazid, Pyroquilon, Pyriofenone, Quinoxyfen, Quintozene, Thiadinyl, Triazoxide, Tricyclazole, Trifolin, Validamycin, Valifenalate, Zoxamide, Mandipropamid, Flubeneteram, Isopyrazam, Sedaxane, Pydiflumetofen, 3-difluoromethyl-1-methyl-1H-pyrazole-4-carboxylic acid (3’,4’,5’-trifluoro-biphenyl-2-yl)-amide, Isoflupiprazam, Isothianil, Diphenamidtron, 6-ethyl-5,7-dioxo-pyrrolo[4,5][1,4]dithieno[1,2-c]isothiazole-3-carbonitrile, 2-(difluoromethyl)-N-[3-ethyl-1,1-dimethyl-indan-4-yl]pyridine-3-carboxamide, 4-(2,6-difluorophenyl)-6-methyl-5-phenyl-pyridazine-3-carbonitrile, (R)-3-(difluoromethyl)-1-methyl-N-[1,1,3-trimethylindan-4-yl]pyrazole-4-carboxamide, 4-(2-bromo-4-fluoro-phenyl)-N-(2-chloro-6-fluoro-phenyl)-2,5-dimethyl-pyrazol-3-amine, 4-(2-bromo-4-fluorophenyl)-N-(2-chloro-6-fluoro-phenyl)-2,5-Dimethyl-pyrazol-3-amine, 4-(2-bromo-4-fluorophenyl)-N-(2-chloro-6-fluorophenyl)-1,3-dimethyl-1H-pyrazol-5-amine, fluindapyr, kresoxim-methyl (jiaxiangjunzhi), ribavirin, dichlobenzthiazone, mandestrobin, 3-(4,4-difluoro-3,4-dihydro-3,3-dimethylisoquinolin-1-yl)quinolone, 2-[2-fluoro-6-[(8-fluoro-2-methyl-3-quinolyl)oxy]phenyl]propan-2-ol, oxathiapiprolin, tert-butyl N-[6-[[[(1-methyltetrazol-5-yl)-phenyl-methylidene]amino]oxymethyl]-2-pyridyl]carbamate, pyraclofamid, imidacloprid, tolprocarb, mefenoxazol, ipconazole, 2-(difluoromethyl)-N-[(3R)-3-ethyl-1,1-dimethyl-indan-4-yl]pyridine-3-carboxamide, N'-(2,5-dimethyl-4-phenoxyphenyl)-N-ethyl-N-methylformamidine, N'-[4-(4,5-dichlorothiazol-2-yl)oxy-2,5-dimethylphenyl]-N-ethyl-N-methylformamidine, [2-[3-[2-[1-[2-[3,5-bis(difluoromethyl)pyrazol-1-yl]acetyl]-4-piperidyl]thiazol-4-yl]-4,5-dihydroisoxazol-5-yl]-3-chlorophenyl]methanesulfonate, but-3-ynyl N-[6-[[(Z)][(1-methyltetrazol-5-yl)-phenyl-methylidene]amino]oxymethyl]-2-pyridyl)carbamate, methyl N-[[5-[4-(2,4-dimethylphenyl)triazol-2-yl]-2-methylphenyl]methyl]carbamate, 3-chloro-6-methyl-5-phenyl-4-(2,4,6-trifluorophenyl)pyridazine, pyridachloromethy, 3-(difluoromethyl)-1-methyl-N-[1,1,3-(Trimethylinden-4-yl)pyrazole-4-carboxamide, 1-[2-[[1-(4-chlorophenyl)pyrazol-3-yl]oxymethyl-3-methyl-phenyl]-4-methyl-tetrazol-5-one, 1-methyl-4-[3-methyl-2-[[2-methyl-4-(3,4,5-trimethylpyrazol-1-yl)phenoxy]methyl]phenyl]tetrazol-5-one, aminopyrifen, ametoctradin, amisulbrom, penflufen, (Z,2E)5-[1-(4-chlorophenyl)pyrazol-3-yl]oxy 2-methoxyimino-N,3-dimethyl-penta-3-enamide, flonicamid, fenpyroximate, metflonicamid, tebufenozide, ifufenozide, chinomethionat, isophthalic amide, ethyl 1-[[4-[[2-(trifluoromethyl)-1,3-dioxolan-2-yl]methoxy]phenyl]methyl]pyrazole-3-carboxylate (which can be prepared by the method described in International Publication No. 2020 / 056090), ethyl 1-[[4-[(Z)-2-ethoxy-3,3,3-trifluoro-prop-1-enoxy]phenyl]methyl]pyrazole-3-carboxylate (which can be prepared by the method described in International Publication No. 2020 / 056090), methyl N-[[4-[1-(4-cyclopropyl-2,6-difluoro-phenyl)pyrazol-4-yl]-2-methyl-phenyl]methyl]carbamate (which can be prepared from the method described in International Publication No. 2020 / 097012), methyl N-[[4-[1-(2,6-difluoro-4-isopropyl-phenyl)-pyrazol-4-yl]-2-methyl-phenyl]methyl]carbamate (which can be prepared from the method described in International Publication No. 2020 / 097012), 6-chloro-3-(3-cyclopropyl-2-fluoro-phenoxy)-N-[2-(2,4-dimethylphenyl)-2,2-difluoro-ethyl]-5-methyl-pyridazine-4-carboxamide (which can be prepared by the method described in International Publication No. 2020 / 109391), 6-chloro-N-[2-(2-chloro-4-methylphenyl)-2,[[2-Difluoroethyl]]-3-(3-Cyclopropyl-2-fluorophenoxy)-5-methyl-pyridazine-4-carboxamide (which can be prepared by the method described in International Publication No. WO 2020 / 109391), 6-Chloro-3-(3-cyclopropyl-2-fluorophenoxy)-N-[[2-(3,4-dimethylphenyl)-2,2-difluoroethyl]]-5-methyl-pyridazine-4-carboxamide (which can be prepared by the method described in International Publication No. WO 2020 / 109391), N-[[2-[2,4-Dichlorophenoxy]phenyl]]-3-(difluoromethyl)-1-methyl-pyrazole-4-carboxamide, N-[[2-[2-Chloro-4-(trifluoromethyl)phenoxy]phenyl]]-3-(difluoromethyl)-1-methyl-pyrazole-4-carboxamide, Benzothiostrobin, Fenamacril, 5-Amino-1,3,4-thiadiazole-2-thiol zinc salt (2:1), Fluopyram, Flufenoxdiam, Fluthianil, Fluopyrimid, Pyrapropoyne, Picarbutrazox, 2-(Difluoromethyl)-N-(3-ethyl-1,1-dimethyl-indan-4-yl)pyridine-3-carboxamide, 2-(Difluoromethyl)-N-((3R)-1,1,3-trimethylindan-4-yl)pyridine-3-carboxamide, 4-[[6-[2-(2,4-Difluorophenyl)-1,1-difluoro-2-hydroxy-3-(1,2,4-triazol-1-yl)propyl]-3-pyridyl]oxy]benzonitrile, Methyltetraprole, 2-(Difluoromethyl)-N-((3R)-1,1,3-trimethylindan-4-yl)pyridine-3-carboxamide, α-(1,1-Dimethylethyl)-α-[4’-(trifluoromethoxy)[1,1'-Biphenyl]-4-yl]-5-pyrimidinemethanol, fluoxapiprolin, enoxastrobin, methyl (Z)-3-methoxy-2-[2-methyl-5-[4-(trifluoromethyl)triazol-2-yl]phenoxy]prop-2-enoate, methyl (Z)-3-methoxy-2-[2-methyl-5-(4-propyltriazol-2-yl)phenoxy]prop-2-enoate, methyl (Z)-2-[5-(3-isopropylpyrazol-1-yl)-2-methyl-phenoxy]-3-methoxy-prop-2-enoate, methyl (Z)-3-methoxy-2-[2-methyl-5-(3-propylpyrazol-1-yl)phenoxy]prop-2-enoate, methyl (Z)-3-methoxy-2-[2-methyl-5-[3-(trifluoromethyl)pyrazol-1-yl]phenoxy]prop-2-enoate (these compounds can be prepared by the method described in International Publication No. 2020 / 079111), methyl (Z)-2-(5-cyclohexyl-2-methyl-phenoxy)-3-methoxy-prop-2-enoate, methyl (Z)-2-(5-cyclopentyl-2-methyl-phenoxy)-3-methoxy-prop-2-enoate (these compounds can be prepared by the method described in International Publication No. 2020 / 193387), 4-[[6-[2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(1,2,4-triazol-1-yl)propyl]-3-pyridyl]oxy]benzonitrile, 4-[[6-[2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(5-sulfanyl-1,2,4-triazol-1-yl)propyl]-3-pyridyl]oxy]benzonitrile, 4-[[6-[2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(5-thioxo-4H-1,2,4-(1,2,4-Triazol-1-yl)propyl]-3-pyridyl]oxy]benzonitrile, trinexapac, kresoxim-methyl, zoxiamycin, copper thiodiazole, zinc thiazole, abamectin, iprodione, carboxylamine, N'-[5-bromo-2-methyl-6-[(1S)-1-methyl-2-propoxyethoxy]-3-pyridyl]-N-ethyl-N-methyl-formamidine, N'-[5-bromo-2-methyl-6-[(1R)-1-methyl-2-propoxyethoxy]-3-pyridyl]-N-ethyl-N-methyl-formamidine, N'-[5-bromo-2-methyl-6-(1-methyl-2-propoxyethoxy)-3-pyridyl]-N-ethyl-N-methyl-formamidine, N'-[5-chloro-2-methyl-6-(1-methyl-2-propoxyethoxy)-3-pyridyl]-N-ethyl-N-methyl-formamidine, N'-[5-bromo-2-methyl-6-(1-methyl-2-propoxyethoxy)-3-pyridyl]-N-isopropyl-N-methyl-formamidine (these compounds can be prepared by the methods described in International Publication No. 2015 / 155075); N'-[5-bromo-2-methyl-6-(2-propoxyethoxy)-3-pyridyl]-N-ethyl-N-methyl-formamidine (this compound can be prepared by the method described in IPCOM000249876D); N-isopropyl-N'-[5-methoxy-2-methyl-4-(2,2,2-trifluoro-1-hydroxy-1-phenylethyl)phenyl]-N-methyl-formamidine, N'-[4-(1-cyclopropyl-2,2,2-trifluoro-1-hydroxy-ethyl)-5, -Methoxy-2-methyl-phenyl]-N-isopropyl-N-methyl-formamidine (these compounds can be prepared by the method described in International Publication No. WO 2018 / 228896); N-ethyl-N'-[5-methoxy-2-methyl-4-[(2-trifluoromethyl)oxetan-2-yl]phenyl]-N-methyl-formamidine, N-ethyl-N'-[5-methoxy-2-methyl-4-[(2-trifluoromethyl)tetrahydrofuran-2-yl]phenyl]-N-methyl-formamidine (these compounds can be prepared by the method described in International Publication No. WO 2019 / 110427); N-[(1R)-1-benzyl-3-chloro-1-methyl-but-3-enyl]-8-fluoro-quinoline-3-carboxamide, N-[(1S)-1-benzyl-3-chloro-1-methyl-but-3-enyl]-8-fluoro-quinoline-3-carboxamide, N-[(1R)-1-benzyl-3,3,3-trifluoro-1-methyl-propyl]-8-fluoro-quinoline-3-carboxamide, N-[(1S)-1-benzyl-3,3,3-trifluoro-1-methyl-propyl]-8-fluoro-quinoline-3-carboxamide, N-[(1R)-1-benzyl-1,3-dimethyl-butyl]-7,8-difluoro-quinoline-3-carboxamide,

[0075] N-[(1S)-1-benzyl-1,3-dimethyl-butyl]-7,8-difluoro-quinoline-3-carboxamide, 8-fluoro-N-[(1R)-1-[(3-fluorophenyl)methyl]-1,3-dimethyl-butyl]quinoline-3-carboxamide, 8-fluoro-N-[(1S)-1-[(3-fluorophenyl)methyl]-1,3-dimethyl-butyl]quinoline-3-carboxamide, N-[(1R)-1-benzyl-1,3-dimethyl-butyl]-8-fluoro-quinoline-3-carboxamide, N-[(1S)-1-benzyl-1,3-dimethyl-butyl]-8-fluoro-quinoline-3-carboxamide,

[0076] N-((1R)-1-benzyl-3-chloro-1-methylbut-3-enyl)-8-fluoroquinoline-3-carboxamide, N-((1S)-1-benzyl-3-chloro-1-methylbut-3-enyl)-8-fluoroquinoline-3-carboxamide (these compounds may be prepared from the methods described in International Publication No. WO 2017 / 153380); 1-(6,7-dimethylpyrazolo[1,5-a]pyridin-3-yl)-4,4,5-trifluoro-3,3-dimethylisoquinoline, 1-(6,7-dimethylpyrazolo[1,5-a]pyridin-3-yl)-4,4,6-trifluoro-3,3-dimethylisoquinoline, 4,4-difluoro-3,3-dimethyl-1-(6-methylpyrazolo[1,5-a]pyridin-3-yl)isoquinoline, 4,4-difluoro-3,3-dimethyl-1-(7-methylpyrazolo[1,5-a]pyridin-3-yl)isoquinoline, 1-(6-chloro-7-methylpyrazolo[1,5-a]pyridin-3-yl)-4,4-difluoro-3,3-dimethylisoquinoline (these compounds may be prepared from the methods described in International Publication No. WO 2017 / 025510); 1-(4,5-dimethylbenzimidazol-1-yl)-4,4,5-trifluoro-3,3-dimethylisoquinoline, 1-(4,5-dimethylbenzimidazol-1-yl)-4,4-difluoro-3,3-dimethylisoquinoline, 6-chloro-4,4-difluoro-3,3-dimethyl-1-(4-methylbenzimidazol-1-yl)isoquinoline, 4,4-difluoro-1-(5-fluoro-4-methylbenzimidazol-1-yl)-3,3-dimethylisoquinoline, 3-(4,4-difluoro-3,3-dimethyl-1-isoquinolyl)-7,8-dihydro-6H-cyclopenta[e]benzimidazole (these compounds may be prepared from the methods described in International Publication No. WO 2016 / 156085);N-Methoxy-N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]cyclopropanecarboxamide, N,2-dimethoxy-N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]propanamide, N-ethyl-2-methyl-N-[[(4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]propanamide, 1-methoxy-3-methyl-1-[[(4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]urea, 1,3-dimethoxy-1-[[(4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]urea, 3-ethyl-1-methoxy-1-[[(4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]urea, N-[[(4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]propanamide, 4,4-dimethyl-2-[[(4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]isoxazolidin-3-one, 5,5-dimethyl-2-[[(4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]isoxazolidin-3-one, ethyl 1-[[(4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]pyrazole-4-carboxylate, N,N-dimethyl-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]-1,2,4-triazol-3-amine (These compounds can be prepared by the methods described in WO 2017 / 055473, WO 2017 / 055469, WO 2017 / 093348 and WO 2017 / 118689.);2-[6-(4-Chlorophenoxy)-2-(trifluoromethyl)-3-pyridyl]-1-(1,2,4-triazol-1-yl)propan-2-ol (this compound can be prepared from the method described in International Publication No. WO2017 / 029179); 2-[6-(4-Bromophenoxy)-2-(trifluoromethyl)-3-pyridyl]-1-(1,2,4-triazol-1-yl)propan-2-ol (this compound can be prepared from the method described in International Publication No. WO2017 / 029179); 3-[2-(1-Chlorocyclopropyl)-3-(2-fluorophenyl)-2-hydroxy-propyl]imidazole-4-carbonitrile (this compound can be prepared from the method described in International Publication No. WO2016 / 156290); 3-[2-(1-Chlorocyclopropyl)-3-(3-chloro-2-fluoro-phenyl)-2-hydroxy-propyl]imidazole-4-carbonitrile (this compound can be prepared from the method described in International Publication No. WO2016 / 156290); (4-Phenoxyphenyl)methyl 2-amino-6-methyl-pyridine-3-carboxylate (this compound can be prepared from the method described in International Publication No. WO2014 / 006945); 2,6-Dimethyl-1H,5H-[1,4]dithino[2,3-c:5,6-c']dipyrrole-1,3,5,7(2H,6H)-tetrone (this compound can be prepared from the method described in International Publication No. WO2011 / 138281); N-Methyl-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzenecarbothioamide; N-Methyl-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide; (Z,2E)-5-[1-(2,4-Dichlorophenyl)pyrazol-3-yl]oxy-2-methoxyimino-N,3-dimethyl-penta-3-enamide (this compound may be prepared from the method described in International Publication No. WO2018 / 153707); N'-(2-Chloro-5-methyl-4-phenoxy-phenyl)-N-ethyl-N-methyl-formamidine;N’-[2-Chloro-4-(2-fluorophenoxy)-5-methyl-phenyl]-N-ethyl-N-methyl-formamidine (this compound can be prepared from the method described in International Publication No. WO 2016 / 202742); 2-(difluoromethyl)-N-[(3S)-3-ethyl-1,1-dimethyl-indan-4-yl]pyridine-3-carboxamide (this compound can be prepared from the method described in International Publication No. WO 2014 / 095675); (5-methyl-2-pyridyl)-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]methanone, (3-methylisoxazol-5-yl)-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]methanone (these compounds can be prepared from the method described in International Publication No. WO 2017 / 220485); 2-oxo-N-propyl-2-[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]acetamide (this compound can be prepared from the method described in International Publication No. WO 2018 / 065414); ethyl 1-[[5-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]-2-thienyl]methyl]pyrazole-4-carboxylate (this compound can be prepared from the method described in International Publication No. WO 2018 / 158365); 2,2-difluoro-N-methyl-2-[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]acetamide, N-[(E)-methoxyiminomethyl]-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide, N-[(Z)-methoxyiminomethyl]-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide, N-[N-methoxy-C-methyl-carboximidoyl]-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide (these compounds can be prepared from the method described in International Publication No. WO 2018 / 202428);

[0077] Microorganisms including the following: Acinetobacter lwoffii, Acremonium alternatum, Acremonium cephalosporium, Acremonium diospyri, Acremonium obclavatum, Adoxophyes orana granulovirus (AdoxGV) (Capex (registered trademark)), Agrobacterium radiobacter strain K84 (Galltrol-A (registered trademark)), Alternaria alternata, Alternaria cassia, Alternaria destruens (Smolder (registered trademark)), Ampelomyces quisqualis (AQ10 (registered trademark)), Aspergillus flavus AF36 (AF36 (registered trademark)), Aspergillus flavus NRRL 21882 (Aflaguard (registered trademark)), Aspergillus spp., Aureobasidium pullulans, Azospirillum (MicroAZ (registered trademark), TAZO B (registered trademark)), Azotobacter, Azotobacter chroocuccum (Azotomeal (registered trademark)), Azotobacter cysts (Bionatural Blooming Blossoms (registered trademark)), Bacillus amyloliquefaciens, Bacillus cereus, Bacillus chitinosphorusBacillus chitinosporus strain CM-1, Bacillus chitinosporus strain AQ746, Bacillus licheniformis strain HB-2 (Biostart (trademark), former Rhizoboost (registered trademark)), Bacillus licheniformis strain 3086 (EcoGuard (registered trademark), Green Releaf (registered trademark)), Bacillus circulans, Bacillus firmus (BioSafe (registered trademark), BioNem-WP (registered trademark), VOTiVO (registered trademark)), Bacillus firmus strain I-1582, Bacillus macerans, Bacillus marismortui, Bacillus megaterium, Bacillus mycoides strain AQ726, Bacillus papillae (Milky Spore Powder (registered trademark)), Bacillus pumilus spp., Bacillus pumilus strain GB34 (Yield Shield (registered trademark)), Bacillus pumilus strain AQ717, Bacillus pumilus strain QST2808 (Sonata (registered trademark), Ballad Plus (registered trademark)), Bacillus sphaericus (VectoLex (registered trademark)), Bacillus spp., Bacillus AQ175 strain, Bacillus genus strain AQ177, Bacillus strain AQ178, Bacillus subtilis strain QST 713 (CEASE (registered trademark), Serenade (registered trademark), Rhapsody (registered trademark)), Bacillus subtilisBacillus subtilis strain QST714 (JAZZ (registered trademark)), Bacillus subtilis strain AQ153, Bacillus subtilis strain AQ743, Bacillus subtilis strain QST3002, Bacillus subtilis strain QST3004, Bacillus subtilis var. Amyloliquefaciens FZB24 (Taegro (registered trademark), Rhizopro (registered trademark)), Bacillus thuringiensis Cry 2Ae, Bacillus thuringiensis Cry1Ab, Bacillus thuringiensis aizawai GC91 (Agree (registered trademark)), Bacillus thuringiensis israelensis (BMP123 (registered trademark), Aquabac (registered trademark), VectoBac (registered trademark)), Bacillus thuringiensis kurstaki (Javelin (registered trademark), Deliver (registered trademark), CryMax (registered trademark), Bonide (registered trademark), Scutella WP (registered trademark), Turilav WP (registered trademark), Astuto (registered trademark), Dipel WP (registered trademark), Biobit (registered trademark), Foray (registered trademark)), Bacillus thuringiensis kurstaki BMP123 (Baritone (registered trademark)), Bacillus thuringiensis kurstaki HD-1 (Bioprotec-CAF / 3P (registered trademark)), Bacillus thuringiensis strain BD#32, Bacillus thuringiensisBacillus thuringiensis strain AQ52, Bacillus thuringiensis var. aizawai (XenTari®, DiPel®), bacteria genus (GROWMEND®, GROWSWEET®, Shootup®), bacteriophage of Clavipacter michiganensis (AgriPhage®, Bakflor®), Beauveria bassiana (Beaugenic®, Brocaril WP®), Beauveria bassiana GHA (Mycotrol ES®, Mycotrol O®, BotaniGuard®), Beauveria brongniartii (Engerlingspilz®, Schweizer Beauveria®, Melocont®), Beauveria genus, Botrytis cinerea, Bradyrhizobium japonicum (TerraMax®), Brevibacillus brevis, Bacillus thuringiensis tenebrionis (Novodor®), BtBooster, Burkholderia cepacia (Deny®, Intercept®, Blue Circle®), Burkholderia gladii, Burkholderia gladioli, Burkholderia spp genus, CBH Canadian Bioherbicide®, Candida butyri, Candida famata, Candida fructus, Candidafructus), Candida glabrata, Candida guilliermondii, Candida melibiosica, Candida oleophila O strain, Candida parapsilosis, Candida pelliculosa, Candida pulcherrima, Candida reukaufii, Candida saitoana (Bio-Coat (registered trademark), Biocure (registered trademark)), Candida sake, Candida genus, Candida tenius, Cedecea dravisae, Cellulomonas flavigena, Chaetomium cochliodes (Nova-Cide (registered trademark)), Chaetomium globosum (Nova-Cide (registered trademark)), Chromobacterium subtsugae strain PRAA4-1T (Grandevo (registered trademark)), Cladosporium cladosporioides, Cladosporium oxysporum, Cladosporium chlorocephalum, Cladosporium genus, Cladosporium tenuissimum, Clonostachys rosea (EndoFine (registered trademark)), Colletotrichum acutatum, Coniothyrium minitans (CotansWG (registered trademark), Coniothyrium genus, Cryptococcus albidus (YIELDPLUS (registered trademark)), Cryptococcus humicola, Cryptococcus infirmo-miniatus, Cryptococcus laurentii, Cryptophlebia leucotreta Granovirus (Cryptex (registered trademark)), Cupriavidus campinensis, Cydia pomonella Granovirus (CYD-X (registered trademark)), Cydia pomonella Granovirus (Madex (registered trademark), Madex (registered trademark) Plus, Madex Max, Carpovirusine (registered trademark)), Cylindrobasidium laeve (Stumpout (registered trademark)), Cylindrocladium, Debaryomyces hansenii, Drechslera hawaiinensis, Enterobacter cloacae Enterobacteriaceae, Entomophtora virulenta (Vektor (registered trademark)), Epicoccum nigrum, Epicoccum purpurascens, Epicoccum genus, Filobasidium floriforme, Fusarium acuminatum, Fusarium chlamydosporum, Fusarium oxysporum (Fusaclean, Biofox C), Fusarium proliferatum, Fusarium genus, Galactomyces geotrichum, Gliocladium catenuulatumcatenulatum)(Primastop (registered trademark), Prestop (registered trademark)), Gliocladium roseum, the genus Gliocladium (SoilGard (registered trademark)), Gliocladium virens (Soilgard (registered trademark)), Granupom (registered trademark), Halobacillus halophilus, Halobacillus litoralis, Halobacillus trueperi, the genus Halomonas, Halomonas subglaciescola, Halovibrio variabilis, Hanseniaspora uvarum, Helicoverpa armigera nucleopolyhedrovirus (Helicovex (registered trademark)), Helicoverpa zea nucleopolyhedrovirus (Gemstar (registered trademark)), Isoflavone-formononetin (Myconate (registered trademark)), Kloeckera apiculata, the genus Kloeckera, Lagenidium giganteum (Laginex (registered trademark)), Lecanicillium longisporum (Vertiblast (registered trademark)), Lecanicillium muscarium (Vertikil (registered trademark)), Lymantria Dispar nucleopolyhedrovirus (Disparvirus (registered trademark)), Marinococcus halophilus, Meira geulakonigii, Metarhizium anisopliaeMetarhizium anisopliae)(Met52®), Metarhizium anisopliae)(Destruxin WP®), Metschnikowia fruticola)(Shemer®), Metschnikowia pulcherrima, Microdochium dimerum)(Antibot®), Micromonospora coerulea, Microsphaeropsis ochracea, Muscodor albus 620(Muscudor®), Muscodor roseus strain A3-5, Mycorrhizae genus(AMykor® Root Maximizer), Myrothecium verrucaria strain AARC-0255(DiTera®), BROS PLUS®, Ophiostoma piliferum strain D97(Sylvanex®), Paecilomyces farinosus, Paecilomyces fumosoroseus)(PFR-97®, PreFeRal®), Paecilomyces linacinus)(Biostat WP®), Paecilomyces lilacinus strain 251(MeloCon WG®), Paenibacillus polymyxa, Pantoea agglomerans)(BlightBan C9-1®), Pantoea genus, Pasteuria genus((Econem®), Pasteuria nishizawaenishizawae), Penicillium aurantiogriseum, Penicillium billai (Jumpstart (registered trademark), TagTeam (registered trademark)), Penicillium brevicompactum, Penicillium frequentans, Penicillium griseofulvum, Penicillium purpurogenum, Penicillium genus, Penicillium viridicatum (registered trademark), Phlebiopsis gigantean (Rotstop) (registered trademark), Phosphomeal (registered trademark), Phytophthora cryptogea, Phytophthora palmivora (Devine) (registered trademark), Pichia anomala, Pichia guilermondii, Pichia membranaefaciens, Pichia onychis, Pichia stipites, Pseudomonas aureofasciens (Spot-Less Biofungicide) (registered trademark), Pseudomonas cepacia, Pseudomonas chlororaphis (AtEze) (registered trademark), Pseudomonas corrugate, Pseudomonas fluorescens strain A506 (BlightBan A506) (registered trademark), Pseudomonas putida, Pseudomonas rectans (Pseudomonasreactans), Pseudomonas, Pseudomonas syringae (Bio-Save (registered trademark)), Pseudomonas viridiflava, Pseudomonas fluorescens (Zequanox (registered trademark)), Pseudozyma flocculosa strain PF-A22 UL (Sporodex L (registered trademark)), Puccinia canaliculata, Puccinia thlaspeos (Wood Warrior (registered trademark)), Pythium paroecandrum, Pythium oligandrum (Polygandron (registered trademark), Polyversum (registered trademark)), Pythium periplocum, Rhanella aquatilis, Rhanella genus, Rhizobia (Dormal (registered trademark), Vault (registered trademark)), Rhizoctonia, Rhodococcus globerulus strain AQ719, Rhodosporidium diobovatum, Rhodosporidium toruloides, Rhodotorula genus, Rhodotorula glutinis, Rhodotorula graminis, Rhodotorula mucilagnosa, Rhodotorula rubra, Saccharomyces cerevisiae, Salinococcus roseus, Sclerotinia minorminor), Sclerotinia minor (SARRITOR (registered trademark)), Scytalidium genus, Scytalidium uredinicola, Spodoptera exigua nuclear polyhedrosis virus (Spod-X (registered trademark), Spexit (registered trademark)), Serratia marcescens, Serratia plymuthica, genus Serratia, Sordaria fimicola, Spodoptera littoralis nucleopolyhedrovirus (Littovir (registered trademark)), Sporobolomyces roseus, Stenotrophomonas maltophilia, Streptomyces ahygroscopicus, Streptomyces albaduncus, Streptomyces exfoliates, Streptomyces galbus, Streptomyces griseoplanus, Streptomyces griseoviridis (Mycostop (registered trademark)), Streptomyces lydicus (Actinovate (registered trademark)), Streptomyces lydicus WYEC-108 (ActinoGrow (registered trademark)), Streptomyces violaceus, Tilletiopsis minor, genus Tilletiopsis, Trichoderma asperellum (T34 Biocontrol (registered trademark)), Trichoderma gamsii (Tenet (registered trademark)), Trichoderma atroviride (Plantmate (registered trademark)), Trichoderma hamatum TH 382, Trichoderma harzianum rifai, TrichodermaTrichoderma harzianum Rifai) (Mycostar (registered trademark)), Trichoderma harzianum T-22 (Trianum-P (registered trademark), PlantShield HC (registered trademark), RootShield (registered trademark), Trianum-G (registered trademark)), Trichoderma harzianum T-39 (Trichodex (registered trademark)), Trichoderma inhamatum, Trichoderma koningii, Trichoderma sp. LC 52 (Sentinel (registered trademark)), Trichoderma lignorum, Trichoderma longibrachiatum, Trichoderma polysporum (Binab T (registered trademark)), Trichoderma taxi, Trichoderma virens, Trichoderma virens (formerly Gliocladium virens GL-21) (SoilGuard (registered trademark)), Trichoderma viride, Trichoderma viride strain ICC 080 (Remedier (registered trademark)), Trichosporon pullulans, Trichosporon sp., Trichothecium sp., Trichothecium roseum, Typhula phacorrhiza strain 94670, Typhula phacorrhiza strain 94671, Ulocladium atrum, Ulocladium oudemansii (Botry-Zen (registered trademark)), Ustilago maydismaidis), various bacteria and auxiliary micronutrients (Natural II (registered trademark)), various fungi (Millennium Microbes (registered trademark)), Verticillium chlamydosporium, Verticillium lecanii (Mycotal (registered trademark), Vertalec (registered trademark)), Vip3Aa20 (VIPtera (registered trademark)), Virgibacillus marismortui, Xanthomonas campestris pv. Poae (Poae (Camperico (registered trademark))), Xenorhabdus bovienii, and Xenorhabdus nematophilus; Plant extracts comprising:

[0078] A plant extract containing the following: Retenol (registered trademark), azadirachtin (Plasma Neem Oil (registered trademark), AzaGuard (registered trademark), MeemAzal (registered trademark), Molt-X (registered trademark), Botanical IGR (Neemazad (registered trademark), Neemix (registered trademark)), rapeseed oil (Lilly Miller Vegol (registered trademark)), Chenopodium ambrosioides near ambrosioides (Requiem (registered trademark)), Chrysanthemum extract (Crisant (registered trademark)), neem oil extract (Trilogy (registered trademark)), essential oil of Labiatae (Botania (registered trademark)), extract of clove, rosemary, peppermint and thyme oil (Garden insect killer (registered trademark)), glycine betaine (Greenstim (registered trademark)), garlic, lemongrass oil (GreenMatch (registered trademark)), neem oil, Nepeta cataria (catnip oil), Nepeta catarina, nicotine, oregano oil (MossBuster (registered trademark)), Pedaliaceae oil (Nematon (registered trademark)), pyrethrum, Quillaja saponaria (NemaQ (registered trademark)), Reynoutria sachalinensis (Regalia (registered trademark), Sakalia (registered trademark)), rotenone (Eco Roten (registered trademark)), Rutaceae extract (Soleo (registered trademark)), soybean oil (Ortho ecosense (registered trademark)), Melaleuca alternifolia (also called tea tree oil) (Timorex Gold (registered trademark)), thyme oil, AGNIQUE (registered trademark) MMF, BugOil (registered trademark), mixture of rosemary, cumin, peppermint, thyme and cinnamon extracts (EF 300 (registered trademark)), mixture of clove, rosemary and peppermint extracts (EF 400 (registered trademark)), mixture of clove, peppermint, garlic oil and mint (SoilShot (registered trademark), kaolin (Screen (registered trademark)), storage glucan of brown algae (Laminarin (registered trademark));

[0079] Pheromones, for example: blackheaded fireworm pheromone (3M Sprayable Blackheaded Fireworm Pheromone (registered trademark)), codling moth pheromone (Paramount dispenser-(CM) / Isomate C-Plus (registered trademark)), grape berry moth pheromone (3M MEC-GBM Sprayable Pheromone (registered trademark)), leafroller pheromone (3M MEC-LR Sprayable Pheromone (registered trademark)), Muscamone (Snip7 Fly Bait (registered trademark), Starbar Premium Fly Bait (registered trademark)), oriental fruit moth pheromone (3M oriental fruit moth sprayable pheromone (registered trademark)), peachtree borer pheromone (Isomate-P (registered trademark)), tomato pinworm pheromone (3M Sprayable pheromone (registered trademark)), Entostat powder (extract from palm tree) (Exosex CM (registered trademark)), (E,Z,Z)-3,8,11-tetradecatrienyl acetate, (Z,Z,E)-7,11,13-hexadecatrienal, (E,Z)-7,9-dodecadien-1-yl acetate, 2-methyl-1-butanol, calcium acetate, Scenturion (registered trademark), Biolure (registered trademark), Check-Mate (registered trademark), lavandulyl senecioate; and

[0080] Macroscopic vials containing the following: Aphelinus abdominalis, Aphidius ervi (Aphelinus)-System (registered trademark), Acerophagus papaya, Adalia bipunctata (Adalia)-System (registered trademark), Adalia bipunctata (Adaline (registered trademark)), Adalia bipunctata (Aphidalia (registered trademark)), Ageniaspis citricola, Ageniaspis fuscicollis, Amblyseius andersoni (Anderline (registered trademark), Andersoni-System (registered trademark)), Amblyseius californicus (Amblyline (registered trademark), Spical (registered trademark)), Amblyseius cucumeris (Thripex (registered trademark), Bugline cucumeris (registered trademark)), Amblyseius fallacis (Fallacis (registered trademark)), Amblyseius swirskii (Bugline swirskii (registered trademark), Swirskii-Mite (registered trademark)), Amblyseius womersleyi (WomerMite (registered trademark)), Amitus hesperidum, Anagrus atomus, Anagyrus fusciventris, Anagyrus kamali, Anagyrus loecki, Anagyrus schuettiPseudococci)(Citripar (registered trademark)), Anicetus benefices, Anisopteromalus calandrae, Anthocoris nemoralis (Anthocoris-System (registered trademark)), Aphelinus abdominalis (Aphelin (registered trademark), Affilin (registered trademark)), Aphelinus asychis, Aphidius colemani (Aphipar (registered trademark)), Aphidius ervi (Ervipar (registered trademark)), Aphidius gifuensis, Aphidius matricariae (Aphipar-M (registered trademark)), Aphidoletes aphidimyza (Aphidend (registered trademark)), Aphidoletes aphidimyza (Aphidoline (registered trademark)), Aphytis lingnanensis, Aphytis melinus, Aprostocetus hagenowii, Atheta coriaria (Staphyline (registered trademark)), genus Bombus, Bombus terrestris (Natupol Beehive (registered trademark)), Bombus terrestris (Beeline (registered trademark), Tripol (registered trademark)), Cephalonomia stephanoderis, Chilocorus nigritus, Chrysoperla carnea (Chrysoline (registered trademark)), Chrysoperla carnea (ChrysoperlaChrysopa carnea (Chrysopa (registered trademark)), Chrysoperla rufilabris, Cirrospilus ingenuus, Cirrospilus quadristriatus, Citrostichus phyllocnistoides, Closterocerus chamaeleon, genus Closterocerus, Coccidoxenoides perminutus (Planopar (registered trademark)), Coccophagus cowperi, Coccophagus lycimnia, Cotesia flavipes, Cotesia plutellae, Cryptolaemus montrouzieri (Cryptobug (registered trademark), Cryptoline (registered trademark)), Cybocephalus nipponicus, Dacnusa sibirica, Dacnusa sibirica (Minusa (registered trademark)), Diglyphus isaea (Diminex (registered trademark)), Delphastus catalinae (Delphastus (registered trademark)), Delphastus pusillus, Diachasmimorpha krausii, Diachasmimorpha longicaudata, Diaparsis jucunda, Diaphorencyrtus aligarhensis, Diglyphus isaea, Diglyphus isaeaisaea) (Miglyphus (registered trademark), Digline (registered trademark)), Dacnusa sibirica (DacDigline (registered trademark), Minex (registered trademark)), Diversinervus genus, Encarsia citrina, Encarsia formosa (Encarsia max (registered trademark), Encarline (registered trademark), En-Strip (registered trademark)), Eretmocerus eremicus (Enermix (registered trademark)), Encarsia haitiensis, Syrphidend (registered trademark), Eretmoceris siphonini, Eretmocerus californicus, Eretmocerus eremicus (Ercal (registered trademark), Eretline e (registered trademark)), Eretmocerus eremicus (Bemimix (registered trademark)), Eretmocerus hayati, Eretmocerus mundus (Bemipar (registered trademark), Eretline m (registered trademark)), Eretmocerus siphonini, Exochomus quadripustulatus, Feltiella acarisuga (Spidend (registered trademark)), Feltiella acarisuga (Feltiline (registered trademark)), Fopius arisanus, Fopius ceratitivorus, Wirless Beehome (registered trademark), Franklinothrips vespiformis (Vespop (registered trademark)), Galendromus occidentalis, Goniozus regneriLegneri), Habrobracon hebetor, Harmonia axyridis (HarmoBeetle (registered trademark)), Heterorhabditis genus (Lawn Patrol (registered trademark)), Heterorhabditis bacteriophora (NemaShield HB (registered trademark), Nemaseek (registered trademark)), Terranem-Nam (registered trademark), Terranem (registered trademark), Larvanem (registered trademark), B-Green (registered trademark), NemAttack (registered trademark), Nematop (registered trademark)), Heterorhabditis megidis (Nemasys H (registered trademark), BioNem H (registered trademark), Exhibitline hm (registered trademark), Larvanem-M (registered trademark)), Hippodamia convergens, Hypoaspis aculeifer (Aculeifer-System (registered trademark), Entomite-A (registered trademark)), Hypoaspis miles (Hypoline m (registered trademark), Entomite-M (registered trademark)), Lbalia leucospoides, Lecanoideus floccissimus, Lemophagus errabundus, Leptomastidea abnormis, Leptomastix dactylopii (Leptopar (registered trademark)), Leptomastix epona, Lindorus lophanthae, Lipolexis oregmae, Lucilia caesar (Natufly (registered trademark)), Lysiphlebus testaceipestestaceipes), Macrolophus caliginosus (Cryptobug (registered trademark), Cryptoline (registered trademark)), Mesoseiulus longipes, Metaphycus flavus, Metaphycus lounsburyi, Micromus angulatus( Milacewing (Registered Trademark), Microterys flavus, Muscidifurax raptorellus, Spalangia cameroni (Biopar (Registered Trademark)), Neodryinus typhlocybae, Neoseiulus californicus, Neoseiulus cucumeris (THRYPEX (Registered Trademark)), Neoseiulus fallacis, Nesideocoris tenuis (NesidioBug (Registered Trademark), Nesibug (Registered Trademark)), Ophyra aenescens (Biofly (Registered Trademark)), Orius insidiosus (Thripor-I (Registered Trademark), Oriline i (Registered Trademark)), Orius laevigatus (Thripor-L (Registered Trademark), Oriline l (Registered Trademark)), Orius majusculus (Oriline m (Registered Trademark)), Orius strigicollis (Thripor-S (Registered Trademark)), Pauesia juniperorum, Pediobius foveolatus, Phasmarhabditis hermaphrodita (Nemaslug (Registered Trademark)) (Registered Trademark), Phymastichus coffea, Phytoseiulus macropilus, Phytoseiulus persimilis (Spidex (Registered Trademark), Phytoline p (Registered Trademark)), Podisus (Registered Trademark), Pseudacteon curvatuluscurvatus), Pseudacteon obtusus, Pseudacteon tricuspis, Pseudaphycus maculipennis, Pseudleptomastix mexicana, Psyllaephagus pilosus, Psyttalia concolor (complex), Quadrastichus genus, Rhyzobius lophanthae, Rodolia cardinalis, Rumina decollate, Steinernema carpocapsae (Nematac C (registered trademark) Millenium (registered trademark), BioNem C (registered trademark), NemAttack (registered trademark), Nemastar (registered trademark), Capsanem (registered trademark)), Steinernema feltiae (NemaShield (registered trademark), Nemasys F (registered trademark), BioNem F (registered trademark), Steinernema-System (registered trademark), NemAttack (registered trademark), Nemaplus (registered trademark), Exhibitline sf (registered trademark), Scia-rid (registered trademark), Entonem (registered trademark)), Steinernema kraussei (Nemasys L (registered trademark), BioNem L (registered trademark), Exhibitline srb (registered trademark)), Steinernema riobrave (Aferin (registered trademark), Affilin (registered trademark)), Steinernema scapterisci (Nematac S (registered trademark)), Steinernema genus, Steinernematid genus (Guardian Nematodes (registered trademark)), Stethorus punctillumpunctillum)(Stethorus (registered trademark)), Tamarixia radiate, Tetrastichus setifer, Thripobius semiluteus, Torymus sinensis, Trichogramma brassicae (Tricholine b (registered trademark)), Trichogramma brassicae (Tricho-Strip (registered trademark)), Trichogramma evanescens, Trichogramma minutum, Trichogramma ostriniae, Trichogramma platneri, Trichogramma pretiosum, Xanthopimpla stemmator;

[0081] Other biological agents including: abscisic acid, bioSea®, Chondrostereum purpureum (Chontrol Paste®), Colletotrichum gloeosporioides (Collego®), copper octanoate (Cueva®), Trapline d®, Erwinia amylovora (harpin) (ProAct®, Ni-HIBIT Gold CST®), fatty acids derived from natural by-products of extra-virgin olive oil (FLIPPER®), ferric phosphate (Ferramol®), Trapline y®, Gallex®, Grower’s Secret®, homo-brassonolide, iron phosphate (Lilly Miller Worry Free Ferramol Slug&Snail Bait®), MCP hail trap (Trapline f®), Microctonus hyperodae, Mycoleptodiscus terrestris (Des-X®), BioGain®, Aminomite®, Zenox®, pheromone trap (Thripline ams®), potassium hydrogen carbonate (MilStop®), potassium salt of fatty acids (Sanova®), potassium silicate solution (Sil-Matrix®), potassium iodide + potassium thiocyanate (Enzicur®), SuffOil-X®, spider venom, Nosema locustae (Semaspore Organic Grasshopper Control®), sticky trap (Trapline YF®, Rebell Amarillo®) and trap (Takitrapline y+b®);。

[0082] (1) An antibacterial agent selected from the following group: (1.1) Examples are as follows: bacteria: Bacillus mojavensis strain R3B from Certis USA LLC (accession number NCAIM(P)B001389) (International Publication No. WO 2013 / 034938); Bacillus pumilus, in particular strain BU F-33 having NRRL accession number 50185 (CARTISSA® from BASF, EPA registration number 71840-19); Bacillus subtilis, in particular strain QST713 / AQ713 (available as SERENADE OPTI or SERENADE ASO from Bayer CropScience LP, US, having NRRL accession number B21661, US Patent No. 6,060,051); Bacillus subtilis strain BU1814 (VELONDIS® PLUS, VELONDIS® FLEX and VELONDIS® EXTRA from BASF SE); Bacillus subtilis var. amyloliquefaciens strain FZB24 having accession number DSM10271 (available as TAEGRO® or TAEGRO® ECO (EPA registration number 70127-5) from Novozymes); Bacillus subtilis CX-9060 from Certis USA LLC; Bacillus sp., in particular strain D747 (available as DOUBLE NICKEL® from Kumiai Chemical Industry Co., Ltd.), having accession number FERM BP-8234, US Patent No. 7,094,592; a Paenibacillus sp. strain having accession number NRRL B-50972 or accession number NRRL B-67129 (International Publication No. WO 2016 / 154297); Paenibacillus polymyxa, in particular strain AC-1 (e.g., Green Biotech Company Ltd.Manufactured TOPSEED (registered trademark)); Pantoea agglomerans, particularly strain E325 (accession number NRRL B-21856) (available as BLOOMTIME BIOLOGICAL (trademark) FD BIOPESTICIDE from Northwest Agri Products); Pseudomonas proradix from Sourcon Padena (e.g., PRORADIX (registered trademark)); and.

[0083] (1.2) Examples thereof are the following fungi: Aureobasidium pullulans, particularly blastospores of strain DSM14940, blastospores of strain DSM14941 or a mixture of blastospores of strains DSM14940 and DSM14941 (e.g., BOTECTOR (registered trademark) and BLOSSOM PROTECT (registered trademark) manufactured by bio-ferm, CH); Pseudozyma aphidis (disclosed in International Publication No. 2011 / 151819 by Yissum Research Development Company of the Hebrew University of Jerusalem); Saccharomyces cerevisiae from Lesaffre et Compagnie, FR, particularly strain CNCM number 1-3936, CNCM number 1-3937, CNCM number 1-3938 or CNCM number 1-3939 (International Publication No. 2010 / 086790);

[0084] (2) Biological fungicides and bactericides selected from the following groups: (2.1) Bacteria, such as Agrobacterium radiobacter strain K84 (e.g., GALLTROL-A® from AgBioChem, CA); Agrobacterium radiobacter strain K1026 (e.g., NOGALL™ from BASF SE); Bacillus subtilis var. amyloliquefaciens strain FZB24 having accession number DSM 10271 (available from Novozymes as TAEGRO® or TAEGRO® ECO (EPA registration number 70127-5)); Bacillus amyloliquefaciens, particularly strain D747 (accession number FERM BP-8234, available from Kumiai Chemical Industry Co., Ltd. as Double Nickel™, having US Patent No. 7,094,592); Bacillus amyloliquefaciens strain F727 (also known as MBI110 strain) (NRRL accession number B-50768, International Publication No. 2014 / 028521) (STARGUS® from Marrone Bio Innovations); Bacillus amyloliquefaciens strain FZB42, accession number DSM 23117 (available from ABiTEP, DE as RHIZOVITAL®); Bacillus amyloliquefaciens isolate B246 (e.g., AVOGREEN™ from Pretoria University); Bacillus licheniformis having accession number ATCC 55406, International Publication No. 2003 / 000051 (available from Novozymes as ECOGUARD® Biofungicide and GREEN RELEAF™), particularly strain SB3086;Bacillus licheniformis FMCH001 and Bacillus subtilis FMCH002 (QUARTZO® (WG) and PRESENCE® (WP) manufactured by FMC Corporation); Bacillus methylotrophicus strain BAC-9912 (manufactured by the Chinese Academy of Sciences’ Institute of Applied Ecology); Bacillus mojavensis strain R3B (accession number NCAIM(P)B001389) of Certis USA LLC (International Publication No. WO 2013 / 034938); Bacillus mycoides isolate having accession number B-30890 (available from Certis USA LLC as BMJ TGAI® or WG and LifeGard®); Bacillus pumilus, particularly strain QST2808 (having accession number NRRL B-30087, described in U.S. Patent No. 6,245,551, available from Bayer CropScience LP, US as SONATA®); Bacillus pumilus, particularly strain GB34 (available from Bayer AG, DE as Yield Shield®); Bacillus pumilus having NRRL accession number 50185 (available as part of the CARTISSA product from BASF, EPA registration number 71840-19), particularly strain BU F-33; Bacillus subtilis, particularly strain QST713 / AQ713 (available from Bayer CropScience LP, US as SERENADE OPTI or SERENADE ASO, having NRRL Accession No. B21661, described in U.S. Patent No. 6,060,051);Bacillus subtilis Y1336 (available from Bion-Tech, Taiwan as BIOBAC® WP, registration numbers 4764, 5454, 5096, 5277 as a biological fungicide in Taiwan); Bacillus subtilis strain MBI 600 (available from BASF SE as SUBTILEX, having accession number NRRL B-50595, U.S. Patent No. 5,061,495); Bacillus subtilis strain GB03 (available from Bayer AG, DE as Kodiak®); Bacillus subtilis strain BU1814 (available from BASF SE as VELONDIS® PLUS, VELONDIS® FLEX and VELONDIS® EXTRA); Bacillus subtilis CX-9060 of Certis USA LLC; Bacillus subtilis KTSB strain (Donaghys' FOLIACTIVE®); Bacillus subtilis IAB / BS03 (STK Bio-Ag Technologies' AVIV™, Idai Nature's PORTENTO®); Bacillus subtilis Y1336 strain (available from Bion-Tech, Taiwan as BIOBAC®), registered as a biological fungicide in Taiwan with registration numbers 4764, 5454, 5096 and 5277); Paenibacillus epiphyticus from BASF SE (International Publication No. 2016 / 020371); Paenibacillus polymyxa plantarum from BASF SE (International Publication No. 2016 / 020371); Paenibacillus species strain having accession number NRRL B-50972 or accession number NRRL B-67129, International Publication No. 2016 / 154297;Accession number NRRL B-50897, International Publication No. 2017 / 019448 (Pseudomonas chlororaphis strain AFS009 having a deposit number (e.g., AgBiome Innovations, HOWLER (trademark) and ZIO (registered trademark) of US); Pseudomonas chlororaphis, particularly strain MA342 (e.g., CEDOMON (registered trademark), CERALL (registered trademark), and CEDRESS (registered trademark) by Bioagri and Koppert); Pseudomonas fluorescens strain A506 (e.g., BLIGHTBAN (registered trademark) A506 by NuFarm); Pseudomonas proradix (e.g., PRORADIX (registered trademark) by Sourcon Padena); Streptomyces griseoviridis strain K61 (also known as Streptomyces galbus strain K61) (Accession number DSM 7206) (manufactured by Verdera's MYCOSTOP (registered trademark), refer to BioWorks' PREFENCE (registered trademark): Crop Protection 2006, 25, 468 - 475); Streptomyces lydicus strain WYEC108 (also known as Streptomyces lydicus strain WYCD108US) (ACTINO-IRON (registered trademark) and ACTINOVATE (registered trademark) from Novozymes); and;

[0085] (2.2) Fungi, such as Ampelomyces quisqualis, especially strain AQ 10 (e.g., AQ 10® from IntrachemBio Italia); Ampelomyces quisqualis AQ10 strain having accession number CNCM 1-807 (e.g., AQ 10® from IntrachemBio Italia); Aspergillus flavus strain NRRL 21882 (product known as AFLA-GUARD® from Syngenta / ChemChina); Blastospores of Aureobasidium pullulans, especially strain DSM14940; Blastospores of Aureobasidium pullulans, especially strain DSM14941; Mixture of blastospores of Aureobasidium pullulans, especially strains DSM14940 and DSM14941 (e.g., BOTECTOR® by bio-ferm, CH); Chaetomium cupreum (accession number CABI 353812) (e.g., BIOKUPRUM™ by AgriLife); Chaetomium globosum (available as RIVADIOM® by Rivale); Cladosporium cladosporioides, H39 strain having accession number CBS122244, US Patent Application Publication No. 2010 / 0291039 (by Stichting Dienst Landbouwkundig Onderzoek); Coniothyrium minitans strain, especially strain CON / M / 91-8 (accession number DSM9660, e.g., Contans® by Bayer CropScience Biologics GmbH); Cryptococcus flavescens, strain 3C (NRRL Y-50378), (B2.2.99); Dactylaria candida; Gliocladium catenulatum (synonym: Clonostachys rosea f. catenulata) J1446 strain (e.g., Prestop® by Lallemand); Gliocladium roseum (synonym Clonostachys rosea f rosea), in particular, strain 321U of Adjuvants Plus, strain ACM941 disclosed by Xue A.G. (Efficacy of Clonostachys rosea strain ACM941 and fungicide seed treatments for controlling the root rot complex of field pea, Can Jour Plant Sci 2003, 83(3):519-524) or strain IK726 (Jensen DF, et al. Development of a biocontrol agent for plant disease control with special emphasis on the near commercial fungal antagonist Clonostachys rosea strain ‘IK726’, Australasian Plant Pathol. 2007, 36(2):95-101); Lecanicillium lecanii (formerly known as Verticillium lecanii) conidia of strain KV01 (e.g., Vertalec® by Koppert / Arysta); Metschnikowia fructicola, in particular strain NRRL Y-30752, (B2.2.3); Microsphaeropsis ochracea; Muscodor roseus, particularly strain A3-5 (Accession No. NRRL 30548); Penicillium steckii from BASF SE (DSM 27859, International Publication No. 2015 / 067800); Penicillium vermiculatum; Phlebiopsis gigantea strain VRA 1992 (ROTSTOP® C manufactured by Danstar Ferment); Pichia anomala, strain WRL-076 (NRRL Y-30842), U.S. Patent No. 7,579,183; Pseudozyma flocculosa, strain PF-A22 UL (available as SPORODEX® L from Plant Products Co., CA, USA); Saccharomyces cerevisiae, particularly strain LASO2 (manufactured by Agro-Levures et Derives), cell wall of strain LAS117 (CEREVISANE® from Lesaffre, ROMEO® from BASF SE), CNCM No. 1-3936, CNCM No. 1-3937, CNCM No. 1-3938, CNCM No. 1-3939 (International Publication No. 2010 / 086790), manufactured by Lesaffre et Compagnie, FR; Simplicillium lanosoniveum; Talaromyces flavus V117b strain; Trichoderma aceleroides JM41R (Accession No. NRRL B-50759) (TRICHO PLUS®, manufactured by BASF SE); Trichoderma asperellum, particularly strain kd (e.g., T-Gro from Andermatt Biocontrol); Accession No. FERM P-16510 (e.g., ECO-HOPE® from Kumiai Chemical Industry), T34 strain (e.g., Biocontrol Technologies S.L., Trichoderma asperellum having T34 Biocontrol by ES or ICC 012 manufactured by Isagro, particularly strain SKT-1; Trichoderma atroviride, particularly strain SC1 (Accession No. CBS 122089, International Publication No. 2009 / 116106 and US Patent No. 8,431,120 (manufactured by Bi-PA)), strain 77B (T77, manufactured by Andermatt Biocontrol) or strain LU132 (e.g., Sentinel of Agrimm Technologies Limited); Trichoderma atroviride, strain CNCM 1-1237 (e.g., Esquive® WP from Agrauxine, FR); Trichoderma atroviride, strain number V08 / 002387; Trichoderma atroviride, NMI strain V08 / 002388; Trichoderma atroviride, NMI strain V08 / 002389; Trichoderma atroviride, NMI strain V08 / 002390; Trichoderma atroviride, LC52 strain (e.g., Tenet of Agrimm Technologies Limited); Trichoderma atroviride, ATCC 20476 strain (IMI 206040); Trichoderma atroviride, T11 strain (IMI352941 / CECT20498); Trichoderma atroviride, SKT-1 strain (FERM P-16510), Japanese Patent Laid-Open No. 11-253151; Trichoderma atroviride, SKT-2 strain (FERM P-16511), Japanese Patent Laid-Open No. 11-253151; Trichoderma atroviride, SKT-3 strain (FERM P-17021), Japanese Patent Laid-Open No. 11-253151; Trichoderma (e.g., TrichoPlus of BASF) fertility; Trichoderma gamsii (formerly T. viride),. ICC080 strain (IMI CC 392151 CABI, e.g., BioDerma by AGROBIOSOL DE MEXICO, S.A.DE C.V.); Trichoderma gamsii (formerly T. viride), strain ICC 080 (IMI CC 392151 CABI) (e.g., BIODERMA® of AGROBIOSOL DE MEXICO, S.A.DE C.V.); Trichoderma harmatum; Trichoderma harmatum with accession number ATCC 28012; Trichoderma harzianum T-22 strain (e.g., Trianum-P by Andermatt Biocontrol or Koppert) or Cepa SimbT5 strain (manufactured by Simbiose Agro); Trichoderma harzianum; Trichoderma harzianum rifai T39 (e.g., Trichodex by Makhteshim, US); Trichoderma harzianum, ITEM 908 strain (e.g., Trianum-P of Koppert); Trichoderma harzianum, TH35 strain (e.g., Root-Pro from Mycontrol); Trichoderma harzianum, strain DB 103 (available as T-GRO® 7456 from Dagutat Biolab); Trichoderma polysporum IMI 206039 strain (e.g., Binab TF WP from BINAB Bio-Innovation AB, Sweden); Trichoderma stromaticum with accession number Ts3550 (e.g., Tricovab of CEPLAC Brazil);Trichoderma virens (also known as Gliocladium virens), particularly strain GL-21 (Certis, SoilGard by US); Trichoderma virens G-41 strain (ROOTSHIELD® PLUS WP and TURFSHIELD® PLUS WP from BioWorks, US), previously known as Gliocladium virens (accession number ATCC 20906); Trichoderma viride strain TV1 (e.g., Trianum-P from Koppert); Trichoderma viride, particularly strain B35 (Pietr et al., 1993, Zesz. Nauk. A R w Szczecinie 161:125-137); a mixture of Trichoderma asperellum strain ICC 012 (also known as Trichoderma harzianum ICC012) having accession number CABI CC IMI 392716 and Trichoderma gamsii (previously T. viride) strain ICC 080 having accession number IMI 392151 (e.g., BIO-TAM™ from Isagro USA, Inc. or BIODERMA® from Agrobiosol de Mexico, S.A.de C.V.); Ulocladium oudemansii strain U3 having accession number NM99 / 06216 (e.g., BOTRY-ZEN® from Botry-Zen Ltd, New Zealand or BOTRYSTOP® from BioWorks, Inc.);Verticillium albo-atrum (formerly V. dahliae) strain WCS850 (e.g., DUTCH TRIG® of Tree Care Innovations), having accession number WCS850, deposited at the Central Bureau for Fungi Cultures; Verticillium chlamydosporium;

[0086] (3) A biological control agent having an effect of improving the growth and / or health of a plant selected from the following group: (3.1) Bacteria such as Azospirillum brasilense (e.g., VIGOR® manufactured by KALO, Inc.); Azospirillum lipoferum (e.g., VERTEX-IF™ manufactured by TerraMax, Inc.); Azorhizobium caulinodans, particularly strain ZB-SK-5; Azotobacter chroococcum, particularly strain H23; Azotobacter vinelandii, particularly strain ATCC 12837; A mixture of Azotobacter vinelandii and Clostridium pasteurianum (available as INVIGORATE® from Agrinos); Bacillus amyloliquefaciens pm414 (LOLI-PEPTA®, manufactured by Biofilm Crop Protection); Bacillus amyloliquefaciens SB3281 (ATCC#PTA-7542, International Publication No. WO 2017 / 205258); Bacillus amyloliquefaciens TJ1000 (available as QUIKROOTS® from Novozymes); Bacillus amyloliquefaciens, particularly strain IN937a; Bacillus amyloliquefaciens, particularly strain FZB42 (e.g., RHIZOVITAL®, manufactured by ABiTEP in Germany); Bacillus amyloliquefaciens BS27 (Accession No. NRRL B-5015); Bacillus cereus family member EE128 (NRRL No. B-50917);Bacillus cereus family member EE349 (NRRL number B-50928); Bacillus cereus, particularly strain BP01 (ATCC 55675, for example, MEPICHLOR® manufactured by Arysta Lifescience in the United States); Bacillus firmus, particularly strain CNMC 1-1582 (for example, VOTIVO® by BASF SE); Bacillus mycoides BT155 (NRRL number B-50921); Bacillus mycoides EE118 (NRRL number B-50918); Bacillus mycoides EE141 (NRRL number B-50916); Bacillus mycoides BT46-3 (NRRL number B-50922); Bacillus pumilus, particularly strain QST2808 (accession number NRRL number B-30087); Bacillus pumilus, particularly strain GB34 (for example, YIELD SHIELD® by Bayer Crop Science in Germany); Bacillus siamensis, particularly strain KCTC 13613T; Bacillus subtilis, particularly strain QST713 / AQ713 (having NRRL accession number B-21661 and described in U.S. Patent No. 6,060,051, available from Bayer CropScience LP, US as SERENADE® OPTI or SERENADE® ASO); Bacillus subtilis, particularly strain AQ30002 (described in accession NRRL number B-50421 and U.S. Patent No. 13 / 330,576); Bacillus subtilis, particularly strain AQ30004 (described in NRRL number B-50455 and U.S. Patent No. 13 / 330,576);Bacillus subtilis strain BU1814 (available from BASF SE as TEQUALIS®), Bacillus subtilis rm303 (from Biofilm Crop Protection as RHIZOMAX®); Bacillus thuringiensis BT013A (NRRL number B-50924), also known as Bacillus thuringiensis 4Q7; a mixture of Bacillus licheniformis FMCH001 and Bacillus subtilis FMCH002 (available as QUARTZO® (WG), PRESENCE® (WP) from FMC Corporation); Bacillus subtilis, particularly the MBI 600 strain (e.g., SUBTILEX® from BASF SE); Bacillus tequilensis, particularly the NII-0943 strain; Bradyrhizobium japonicum (e.g., OPTIMIZE® from Novozymes); Delftia acidovorans, particularly the RAY209 strain (BIOBOOST® from Brett Young Seeds); Mesorhizobium cicer (e.g., NODULATOR from BASF SE); Lactobacillus species (LACTOPLANT® from LactoPAFI); Rhizobium leguminosarium biovar viciae (e.g., NODULATOR from BASF SE); Pseudomonas proradix (PRORADIX® from Sourcon Padena); Pseudomonas aeruginosa, particularly the PN1 strain;Rhizobium leguminosarum, particularly the vehicle strain Z25 (Accession Number CECT 4585); Paenibacillus polymyxa, particularly the AC-1 strain (e.g., TOPSEED® of Green Biotech Company Ltd.); Serratia marcescens, particularly the SRM strain (Accession Number MTCC 8708); Sinorhizobium meliloti strain NRG-185-1 (NITRAGIN® GOLD manufactured by Bayer CropScience); Thiobacillus species (e.g., CROPAID® of Cropaid Ltd UK); and;

[0087] (3.2) Fungi, such as Purpureocillium lilacinum (formerly known as Paecilomyces lilacinus) strain 251 (AGAL 89 / 030550, e.g., BioAct from Bayer CropScience Biologics GmbH); Penicillium bilaiae, ATCC strain 22348 (e.g., JumpStart® from Acceleron BioAg), Talaromyces flavus, strain V117b; Trichoderma atroviride CNCM 1-1237 strain (e.g., Esquive® WP from Agrauxine, FR), Trichoderma viride, e.g., strain B35 (Pietr et al., 1993, Zesz. Nauk.A R w Szczecinie 161:125 - 137); Trichoderma atroviride LC52 strain (also known as Trichoderma atroviride strain LU132, e.g., Sentinel from Agrimm Technologies Limited); Trichoderma atroviride strain SC1 (described in International Publication No. 2009 / 116106); Trichoderma asperellum strain kd (e.g., T - Gro from Andermatt Biocontrol); Trichoderma asperellum strain (Plant Health Products, EcoT from ZA); Trichoderma harzianum T - 22 strain (e.g., Trianum - P from Andermatt Biocontrol or Koppert); Myrothecium verrucaria AARC - 0255 strain (e.g., DiTera (trademark) from Valent Biosciences); Penicillium bilaii ATCC ATCC20851; Phytium oligodendrum strain M1 (ATCC 38472, e.g., Polyversum from Bioprepraty of CZ); Trichoderma virens strain GL - 21 (e.g., SoilGard (registered trademark) from Certis USA); Verticillium albo - atrum (formerly V. dahliae) strain WCS850 (CBS 276.92, e.g., Dutch Trig from Tree Care Innovations); Trichoderma atroviride, particularly strain No. V08 / 002387, No. NMI No. V08 / 002388, No. NMI No. V08 / 002389, No. NMI No.Strain V08 / 002390; Strain Trichoderma harzianum ITEM 908, Trichoderma harzianum, Strain TSTh20; Strain Trichoderma harzianum 1295-22; Strain Phytium oligandrum DV74; Rhizophogon amylopogon (Myco-Sol manufactured by Agri-Enterprise, LLC (formerly Helena Chemical Company)); Rhizophogon fulvigleba (e.g., Myco-Sol manufactured by Agri-Enterprise, LLC (formerly Helena Chemical Company)); Strain Trichoderma virens GI-3;.

[0088] (4) An insecticidally effective biological control agent selected from the following (4.1) Bacteria, such as Agrobacterium radiobacter strain K84 (Galltrol, manufactured by AgBiochem Inc.); Bacillus amyloliquefaciens, particularly strain PTS-4838 (e.g., AVEO of Valent Biosciences, US); Bacillus firmus, particularly strain CNMC 1-1582 (e.g., VOTIVO® of BASF SE); Bacillus mycoides, isolate J (e.g., BmJ of Certis USA LLC); Bacillus sphaericus, particularly serotype H5a5b strain 2362 (ABTS-1743 strain) (e.g., VECTOLEX® of Valent BioSciences, US); Bacillus thuringiensis subsp. aizawai, particularly strain ABTS-1857 (SD-1372, e.g., XENTARI® manufactured by Valent BioSciences); Bacillus thuringiensis subsp. aizawai, particularly serotype H-7 (e.g., FLORBAC® WG of Valent BioSciences, US); Bacillus thuringiensis israelensis strain BMP 144 (e.g., AQUABAC® by Becker Microbial Products IL); Bacillus thuringiensis subsp. israelensis (serotype H-14) strain AM65-52 (accession number ATCC 1276) (e.g., VECTOBAC® by Valent BioSciences, US); Bacillus thuringiensis subsp. aizawai strain GC-91;Bacillus thuringiensis var. Colmeri (e.g., TIANBAOBTC by Changzhou Jianghai Chemical Factory); Bacillus thuringiensis var. japonensis strain Buibui; Bacillus thuringiensis subsp. kurstaki strain BMP 123 (manufactured by Becker Microbial Products, IL, BARITONE of Bayer CropScience); Bacillus thuringiensis subsp. kurstaki strain HD-1 (e.g., DIPEL® ES of Valent BioSciences, US); Bacillus thuringiensis var. kurstaki strain EVB-113-19 (e.g., BIOPROTEC® of AEF Global, Bacillus thuringiensis subsp. kurstaki strain ABTS 351, Bacillus thuringiensis subsp. kurstaki strain PB 54, Bacillus thuringiensis subsp. kurstaki SA 11 (Certis, JAVELIN of US), Bacillus thuringiensis subsp. kurstaki SA 12 (Certis, THURICIDE of US); Bacillus thuringiensis subsp. kurstaki strain EG 2348 (Certis, LEPINOX of US); Bacillus thuringiensis subsp. kurstaki strain) EG7841 (CRYMAX by Certis, US);Bacillus thuringiensis subsp. tenebrionis strain NB176 (SD-5428, e.g., NOVODOR® FC from BioFa DE); Brevibacillus laterosporus (LATERAL from Ecolibrium Biologicals); Burkholderia spp., particularly Burkholderia rinojensis strain A396 (also known as Burkholderia rinojensis strain MBI 305) (accession number NRRL B-50319; International Publication Nos. WO 2011 / 106491 and WO 2013 / 032693; e.g., MBI206 TGAI and ZELTO® from Marrone Bio Innovations); Chromobacterium subtsugae, particularly strain PRAA4-1T (e.g., MBI-203; e.g., GRANDEVO® from Marrone Bio Innovations); Lecanicillium muscarium Ve6 (MYCOTAL from Koppert); Paenibacillus popilliae (formerly Bacillus popilliae; e.g., MILKY SPORE POWDER™ or MILKY SPORE GRANULAR™ from St. Gabriel Laboratories); Pasteuria nishizawae strain Pn1 (CLARIVA from Syngenta / ChemChina); Serratia entomophila (e.g., INVADE® by Wrightson Seeds); Serratia marcescens, particularly strain SRM (accession number MTCC 8708); Trichoderma asperellum (TRICHODERMAX from Novozymes);Wolbachia pipientis strain ZAP (e.g., ZAP MALES (R) from MosquitoMate); and;

[0089] (4.2) Fungi, such as: Beauveria bassiana strain ATCC 74040 (e.g., NATURALIS (R) from Intrachem Bio Italia); Beauveria bassiana strain GHA (accession number ATCC74250, e.g., BOTANIGUARD (R) ES and MYCONTROL - O (R) from Laverlam International Corporation); Beauveria bassiana strain ATP02 (accession number DSM24665); Isaria fumosorosea (formerly known as Paecilomyces fumosoroseus) strain Apopka 97) PREFERAL from SePRO; Metarhizium anisopliae 3213 - 1 (deposited under NRRL accession number 67074) (disclosed in International Publication No. 2017 / 066094; Pioneer Hi - Bred International); Metarhizium robertsii 15013 - 1 (deposited under NRRL accession number 67073); Metarhizium robertsii 23013 - 3 (deposited under NRRL accession number 67075); Paecilomyces lilacinus strain 251 (MELOCON from Certis, US); Zoophtora radicans;

[0090] (5) Viruses selected from the group consisting of: Adoxophyes orana granulosis virus (GV); Cydia pomonella granulosis virus (GV); Helicoverpa armigera (cotton bollworm) nucleopolyhedrovirus (NPV); Spodoptera exigua mNPV; Spodoptera frugiperda (fall armyworm) mNPV; Spodoptera littoralis NPV;

[0091] (6) Bacteria and fungi that can be added as "inoculant strains" to plants, plant parts or plant tissues selected from the following and that promote plant growth and plant health due to their specific properties: Agrobacterium spp.; Azorhizobium caulinodans; Azospirillum spp.; Azotobacter spp.; Bradyrhizobium spp.; Burkholderia spp., in particular Burkholderia cepacia (formerly known as Pseudomonas cepacia); Gigaspora spp. or Gigaspora monosporum; Glomus spp.; Laccaria spp.; LactoBacillus buchneri; Paraglomus spp.; Pisolithus tinctorus; Pseudomonas spp.; Rhizobium spp., in particular Rhizobium trifolii; Rhizopogon spp.; Scleroderma spp.; Suillus spp.; Streptomyces spp.;

[0092] (7) Products formed by microorganisms containing proteins and secondary metabolites that can be used as biological control agents selected from plant extracts and Allium sativum (NEMGUARD of EcoSpray; BRALIC manufactured by ADAMA); before Armour; Artemisia absinthium; azadirachtin (e.g., AZATIN XL manufactured by Certis, USA); Bio-Keeper WP; Brassicaceae extracts, especially Brassica powder or mustard powder; Cassia nigricans; Celastrus angulatus; tapeworm (Chenopodium anthelminticum); chitin; Dryopteris filix-mas; Equisetum arvense; Fortune Aza; fungal hops; Chenopodium quinoa saponin extract from quinoa seeds (e.g., Heads Up® (saponin of Quinoa) from Heads Up plant Protectants, CA); naturally occurring Blad polypeptide extracted from Lupin seeds (PROBLAD® of Certis EU); naturally occurring Blad polypeptide extracted from Lupin seeds (FRACTURE® from FMC); pyrethrum / pyrethrin; Quassia amara; Kelcaus; Kiwifruit extract (QL AGRI 35 manufactured by BASF); Reynoutria sachalinensis extract (REGALLIA, REGALIA MAXX manufactured by Marrone Bio); "Requiem® Insecticide"; rotenone; Ryania / ryanodine; Symphytum officinale; Tanacetum vulgare; thymol; thymol mixed with geraniol (CEDROZ of Eden Research); thymol mixed with geraniol and eugenol (Mevaron manufactured by Eden Research); Trial 70; Tricon;Tropaeulum majus; Melaleuca alternifolia extract (TIMOREX GOLD manufactured by STK); Urtica dioica; veratrine; and Viscum album; and; Toxicity relaxants such as benoxacol, cloxytocet (including cloxytocet methyl), cyprosulfamide, dichloramide, fenchlorazole (including fenchlorazole-ethyl), fenchlorim, flurxyphenium, furilazole, isoxadifen (including isoxadifen-ethyl), mefenpyr (including mefenpyr-diethyl), metcamifene and oxabetrinil may be mentioned.

[0093] The weight ratio of the compound of formula I to compound II can preferably be 100:1 to 1:100, 50:1 to 1:50, 20:1 to 1:40, 15:1 to 1:30, 12:1 to 1:25, 10:1 to 1:20, 5:1 to 1:15, 3:1 to 1:10 or 2:1 to 1:5.

[0094] In a preferred embodiment, the pesticidal composition can comprise at least one further fungicide and optionally can further comprise at least one insecticide and / or at least one nematicide.

[0095] When the crystalline polymorph of the present invention is combined with at least one additional fungicide, the following mixtures of the polymorph of formula I and compound II are preferred: mixtures with compounds selected from the group consisting of: petroleum oil, 1,1-bis(4-chlorophenyl)-2-ethoxyethanol, 2,4-dichlorophenylbenzenesulfonate, 2-fluoro-N-methyl-N-1-naphthylacetamide, 4-chlorophenylphenylsulfone, acetoprole, aldoxycarb, amidithion, amidithioate, amiton, hydrogen oxalate amiton, amitraz, aramite, arsenous acid, azobenzene, azothoate, benomyl, benoxaphos, benzyl benzoate, bixafen, brofenvalerate, bromocyclene, bromopropylate, buprofezin, butocarboxim, butoxycarboxim, butylpyridaben, calcium polysulfide, camphechlor, carbaryl, carbophenothion, cymiazole, cinomethionat, chlorbendide, chlordimeform, chlordimeform hydrochloride, chlorphenesol, chlorphensone, chlorphenesulfide, chlorobenzilate, chloromethiuron, chloropropylate, chlorpyrifos, cinerin I, cinerin II, cinerin, chrysanthemum cinerariifolium, coumaphos, chlorotoluron, chlorpyrifos, chlorpyrifos methyl, cyanothoate, DCPM, DDT, demephion, demephion-O, demephion-S, demeton-methyl, demeton-O, demeton-O-methyl, demeton-S, demeton-S-methyl, demeton-S-methyl sulfone, dichlofluanid, dichlorvos, dicliphos, dienochlor, dimefox, dinex, dinex·dicrexine, dinocap-4, dinocap-6, dinoceton, dinopenton, dinosulfon, dinoterbon, dioxathion, diphenylsulfone, disulfiram, DNOC, dorfenapyn, doramectin, endothion, eprinomectin, ethothiomethy, ethirimfos, phenazaflo, fenbutatin oxide, fenthioncarb, fenpyrazamine, fenson, fentrifanil, flubendiamide, flucycloxuron, fluenethi, fluorobenzide, FMC1137, formetanate, formetanate hydrochloride,Hormaphanate, gamma-HCH, Gliodine, Halfenprox, Hexadecyl cyclopropanecarboxylate, Isocarbophos, Jasmonin I, Jasmonin II, Iodofenphos, Lindane, Malonoben, Mecarbam, Mesulfenfos, Methacrifos, Methyl bromide, Methocarb, Mexacarbate, Milbemycin oxime, Mipafox, Monocrotophos, Morphothion, Moxidectin, Naled, 4-Chloro-2-(2-chloro-2-methyl-propyl)-5-[(6-iodo-3-pyridyl)methoxy]pyridazin-3-one, Niflurid, Nikkomycin, Nitrilacarb, Nitrilacarb 1:1 zinc chloride complex, Omethoate, Oxydeprofos, Oxydisulfoton, pp'-DDT, Parathion, Permethrin, Fenchlorphos, Phosphorothioate, Phosphorothioate, Phosphamidon, Polychloroterpene, Polynactin, Proclonol, Promacyl, Propoxur, Prothidathion, Propatate, Pyrethrin I, Pyrethrin II, Pyrethrin, Pyridafenthion, Pyrimidate, Quinalphos, Quintozene, R-1492, Phosphoglycine, Rotenone, Schrader, Sebufos, Selamectin, Sofamed, SSI-121, Sulfiram, Sulfuramid, Sulfotepp, Sulfur, Diflubenzuron, Tau-fluvalinate, TEPP, Terbum, Tetradifon, Tetrasul, Thiafenox, Thiocarb, Thiofanox, Thiamethoxam, Thioquinox, Thiuramgensine, Triamiphos, Triarathene, Triazophos, Triazolone, Triphenolphos, Trinactin, Bamidothion, Vaniliprole, Vetoxazine, Copper dioctanoate, Copper sulfate, Sibutramine, Dicloran, Dichlorophen, Endothal, Fentin, Lime hydroxide, Nabam, Quinoclamine, Quinamide, Simazine, Triphenyltin acetate, Triphenyltin hydroxide, Crufomate, Piperazine, Thiophanate, Chloralose, Fenthion, Pyridin-4-amine, Strychnine, 1-Hydroxy-1H-pyridine-2-thione, 4-(Quinoxalin-2-ylamino)benzenesulfonamide, 8-Hydroxyquinoline sulfate, Bronopol, Copper hydroxide, Cresol, Dipyrithione, Dodecin, Phenaminosulf, Formaldehyde, Hydroxyphenyl,Kasugamycin, kasugamycin hydrochloride hydrate, nickel bis(dimethyldithiocarbamate), nitrapyrin, octyl inonate, oxolinic acid, oxytetracycline, potassium hydroxyquinoline sulfate, probenazole, streptomycin, streptomycin sesquisulfate, tecnazene, thimerosal, Adoxophyes orana GV, Agrobacterium radiobacter, Amblyseius spp., Anagrapha falcifera NPV, Anagrus atomus, Aphelinus abdominalis, Aphidius colemani, Aphidoletes aphidimyza, Autographa californica NPV, Bacillus sphaericus Neide, Beauveria brongniartii, Chrysoperla carnea, Cryptolaemus montrouzieri, Cydia pomonella GV, Dacnusa sibirica, Diglyphus isaea, Encarsia formosa, Eretmocerus eremicus, Heterorhabditis bacteriophora and H. megidis, Hippodamia convergens, Leptomastix dactylopii, Macrolophus caliginosus,Mamestra brassicae NPV, Metaphycus helvolus, Metarhizium anisopliae var. acridum, Metarhizium anisopliae var. anisopliae, Neodiprion sertifer NPV and N. lecontei NPV, genus Orius, Paecilomyces fumosoroseus, Phytoseiulus persimilis, Steinernema bibionis, Steinernema carpocapsae, Steinernema feltiae, Steinernema glaseri, Steinernema riobrave, Steinernema riobravis, Steinernema scapterisci, genus Steinernema, genus Trichogramma, Typhlodromus occidentalis, Verticillium lecanii, apholate, bisazir, busulfan, dimatif, hemer, hempa, metepa, methiotepa, methyl apholate, moldid, penfluron, tepa, thiohempa, thiotepa, tretamine, uredepa, (E)-deca-5-en-1-yl acetate and (E)-deca-5-en-1-ol, (E)-trideca-4-en-1-yl acetate, (E)-6-methylhepta-2-en-4-ol, (E,Z)-tetradeca-4,10-dien-1-yl acetate, (Z)-dodeca-7-en-1-yl acetate, (Z)-hexadeca-11-enal,(Z)-Hexadec-11-en-1-yl acetate, (Z)-hexadec-13-en-11-in-1-yl acetate, (Z)-icos-13-en-10-one, (Z)-tetradec-7-en-1-al, (Z)-tetradec-9-en-1-ol, (Z)-tetradec-9-en-1-yl acetate, (7E,9Z)-dodeca-7,9-dien-1-yl acetate, (9Z,11E)-tetradeca-9,11-dien-1-yl acetate, (9Z,12E)-tetradeca-9,12-dien-1-yl acetate, 14-methyloctadec-1-ene, 4-methylnonan-5-ol and 4-methylnonan-5-one, α-multistritin, brevicomin, codlelure, codlemone, curculure, disparlure, dodec-8-en-1-yl acetate, dodec-9-en-1-yl acetate, dodeca-8,10-dien-1-yl acetate, dominicalure, ethyl 4-methyloctanoate, eugenol, frontalin, grandlure, grandlure I, grandlure II, grandlure III, grandlure IV, hexalure, ipsdienol, ipsenol, japonilure, linaethin, littlelure, looplure, medlure, megatomidic acid, methyleugenol, muscalure, octadeca-2,13-dien-1-yl acetate, octadeca-3,13-dien-1-yl acetate, orfralure, ortholure, ostramone, siglure, soldacine, sulcatol, tetradec-11-en-1-yl acetate, trimedlure, trimedlure A, trimedlure B1, trimedlure B2, trimedlure C, trankcol, 2-(octylthio)ethanol, butopyrone oxide, butoxy(polypropylene glycol), dibutyl adipate, dibutyl phthalate, dibutyl succinate, diethyltoluamide, dimethylcarbamate, dimethyl phthalate, ethylhexanediol, hexamide, methoxybutyl, methyl neodecanamide, oxamate, picaridin, 1-dichloro-1-nitroethane, 1,1-dichloro-2,2-bis(4-ethylphenyl)ethane, 1,2-dichloropropane, 1,3-dichloropropene, 1-bromo-2-chloroethane, 2,2,2-trichloro-1-(3,4-dichlorophenyl)ethyl acetate, 2,2-dichlorovinyl 2-ethylsulfinylethyl methyl phosphate, 2-(1,3-dithiolan-2-yl)phenyl dimethylcarbamate, 2-(2-butoxyethoxy)ethyl thiocyanate, 2-(4,5-dimethyl-1,3-dioxolan-2-yl)phenyl methylcarbamate, 2-(4-chloro-3,5-xylyloxy)ethanol, 2-chlorovinyl diethyl phosphate, 2-imidazolidone, 2-isovalerylindole-1,3-dione, 2-methyl(prop-2-ynyl)aminophenyl methylcarbamate, 2-thiocyanatoethyl laurate, 3-bromo-1-chloroprop-1-ene, 3-methyl-1-phenylpyrazol-5-yl dimethylcarbamate, 4-methyl(prop-2-ynyl)amino-3,5-xylyl methylcarbamate, 5,5-dimethyl-3-oxocyclohex-1-enyl dimethylcarbamate, acetion, acrylonitrile, aldrin, alloxydim, alicarb, α-endosulfan, aluminum phosphide, aminocarb, anabasine, atidathion, azamethiphos, Bacillus thuringiensis·delta-endotoxin, barium hexafluorosilicate, barium polysulfide, barthrin, Bayer 22 / 190, Bayer 22408, β-cyfluthrin, β-cyphenothrin, bioethanomethrin, biopermethrin, bis(2-chloroethyl) ether, borax, bromfenvinphos, bromo-DDT, bufencarb, butacarb, butathiofos, butonate, calcium arsenate, calcium cyanide, carbon disulfide, carbon tetrachloride, cartap hydrochloride, sevin, chlorpyrifos cyclene, chlordane, chlordecone, chloroform, chloropicrin, chlorfenoxim, chlorpyrifos, cis-resmethrin, cis-methrin, chlorthiophos, copper acetoarsenite, copper arsenate, copper oleate, cumylphosphate, cryolite, CS-708, cyanofenphos, cyanophos, cyclothrin, cysthionate,d-Tetramethrin, DAEP, Dazomet, Dichlofenthion, Dicresyl, Dicloran, Dicrotophos, Dieldrin, Diethyl, 5-Methylpyrazol-3-yl Phosphate, Dilor, Dimethoate, Dimethoate, Dimethylvinphos, Dimethylamine, Dinoprop, Dinoseb, Dinoseb acetate, Diphenylamine, Dioxabenzofos, Dichlorvos, DSP, Ecdysterone, EI1642, EMPC, EPBP, Ethion, Ethiofencarb, Ethyl formate, Ethylene dibromide, Ethylene dichloride, Ethylene oxide, EXD, Fenchlorphos, Fenethacarb, Fenitrothion, Phenoxycarb, Fenpyridine, Fensulfothion, Fenthion-ethyl, Flucofuron, Phosphamidon, Phosphocarb, Phosphothioethane, Fluchloralin, Fresnelin, Guazatine, Guazatine acetate, Sodium tetrathiocarboxylate, Halfenprox, HCH, HEOD, Heptachlor, Heterophos, HHDN, Hydrogen cyanide, Hikunolcarb, IPSP, Isazofos, Isobenzan, Isodrin, Isofenphos, Isolan, Iprothiolan, Isoxathion, Juvenile hormone I, Juvenile hormone II, Juvenile hormone III, Kelthane, Kinoprene, Lead arsenate, Leptophos, Lilium phosphide, Lysidate, m-Cumenylmethylcarbamate, Magnesium phosphide, Majidox, Mecarbam, Menazon, Mercury chloride, Mesulfenfos, Metam, Metam potassium, Metam sodium, Fluoromethanesulfonyl fluoride, Methocrotophos, Methoprene, Methothrin, Methoxychlor, Methyl isothiocyanate, Methyl chloroform, Methylene chloride, Methoxadiazone, Myrex, Naphthalophos, Naphthalene, NC-170, Nicotine, Nicotine sulfate, Nithiazine, Nornicotine, O-5-Dichloro-4-iodophenyl, O-Ethylethylphosphonothioate, O,O-Diethyl, O-4-Methyl-2-oxo-2H-chromen-7-yl Phosphorothioate, O,O-Diethyl, O-6-Methyl-2-propylpyrimidin-4-yl Phosphorothioate, O,O,O’,O’-Tetrapropyl dithiophosphate, Oleic acid, Paradichlorobenzene, Parathion-methyl, PentachlorophenolPentachlorophenyl laurate, PH60-38, fencaptan, phosphonicochlorid, phosphine, hydroxymethyl, pirimiphos-methyl, polychlorodicyclopentadiene isomers, potassium arsenite, potassium thiocyanate, precocene I, precocene II, precocene III, primidophos, profluthrin, promecarb, prothiofos, pyrazophos, pyresmethrin, quassia, quinalphos-methyl, quinothion, rafoxanide, resmethrin, rotenone, cadethrin, ryania, ryanodine, sabadilla, schradan, sebufos, SI-0009, thiapronyl, sodium arsenite, sodium cyanide, sodium fluoride, sodium hexafluorosilicate, sodium pentachlorophenoxide, sodium selenate, sodium thiocyanate, sulcofuron, sulcofuron sodium, sulfuryl fluoride, sulprofos, tall oil, tadimcarb, TDE, tebupirimfos, temephos, terallethrin, tetrachloroethane, trichlorphon, thicyclam, thicyclam hydrogen oxalate, thionazin, thiosultap, thiosultap sodium, tralomethrin, transpermethrin, triazamate, trichlorometaphos-3, trichloronate, trimethacarb, tolprocarb, triclocarban, triprene, veratridine, veratrin, XMC, zetamethrin, zinc phosphide, zolaprofos, meperfluthrin, tetramethylfluthrin, bis(tributyltin) oxide, bromoacetamide, ferric phosphate, niclosamide-olamine, tributyltin oxide, pyrimorph, trifenmorph, 1,2-dibromo-3-chloropropane, 1,3-dichloropropene, 3,4-dichlorotetrahydrothiophene 1,1-dioxide, 3-(4-chlorophenyl)-5-methyl rhodanine, 5-methyl-6-thioxo-1,3,5-thiadiazinan-3-yl acetic acid, 6-isopentenylaminopurine, aniloflupyr, benclothiaz, cytokinin, DCIP, furfural, isamidophos, kinetin, Myrothecium verrucaria composition, tetrachlorothiophene, xylenol, zeatin, potassium ethylxanthate, acylbenzolar, acylbenzolar-S-methyl,Extract of Reynoutria sachalinensis, α-chlorohydrin, antiu, barium carbonate, bisthiosemid, brodifacoum, bromadiolone, bromethalin, chlorophacinone, cholecalciferol, cumachlor, coumafuryl, coumatetralyl, crimidine, diphenacoum, diphacinone, difethialone, ergocalciferol, flocoumafen, fluoroacetamide, flupropazide, flupropazide hydrochloride, norbormide, phosacetim, phosphorus, pindone, pirinuron, cyclocydrin, sodium fluoroacetate, thallium sulfate, warfarin, 2-(2-butoxyethoxy)ethyl piperonylarate, 5-(1,3-benzodioxol-5-yl)-3-hexylcyclohex-2-enone, farnesol and nerolidol, barbital, MGK264, piperonyl butoxide, piprotal, propyl isomer, S421, sesamex, sesamolin, sulfoxide, anthraquinone, copper naphthenate, copper oxychloride, dicyclopentadiene, thiram, zinc naphthenate, dilan, imanin, ribavirin, chloroincanazide, mercury oxide, thiophanate methyl, azaconazole, bitertanol, bromoconazole, cyproconazole, difenoconazole, diniconazole, epoxyconazole, flubutrazol, flusilazole, flutriafol, flutriafol, hexaconazole, imazalil, imibenconazole, ipconazole, metconazole, microbutanyl, paclobutrazol, pefurazoate, penconazole, prothioconazole, pyrifenox, procraz, propiconazole, pyrimethanil, pyrimethanil, fenpiclonil, fludioxonil, benalaxyl, fluralaxyl, metalaxyl, R-metalaxyl, ofurace, oxadixyl, carbendazim, decarb, fuberidazole, thiabendazole, chlorozolinate,Diclorozolin, Microzolin, Procymidone, Vinclozolin, Boscalid, Carboxin, Fenfluramide, Flutolanil, Mepronil, Oxathiapiprolin, Penthiopyrad, Tiffuthramide, Dodine, Iminoctadine, Azoxystrobin, Dimoxystrobin, Enestrobin, Fenamidstrobin, Fluopicoxystrobin, Fluoxastrobin, Kresoxim-methyl, Metominostrobin, Trifloxystrobin, Orysastrobin, Picoxystrobin, Pyraclostrobin, Pyrametostrobin, Pyraoxystrobin, Ferbam, Mancozeb, Maneb, Metiram, Propineb, Zineb, Captan, Captfol, Fluoroimide, Folpet, Tolylfluanid, Bordeaux mixture, Copper oxide, Mancopper, Copper oxine, Nitrothalisopropyl, Edifenphos, Iprobenfos, Phosphodifen, Tolclofos-methyl, Anilazine, Bentiavalicarb, Blasticidin S, Chloroneb, Chlorothalonil, Ciflumetofen, Simoxanil, Cyclobutriflam, Diclocymet, Dicromedin, Dichloran, Diethofencarb, Dimethomorph, Flumorph, Dithianon, Ethaboxam, Etridiazole, Famoxadone, Fenamidone, Phenoxanil, Ferimzone, Fluazinam, Flume-thosulfuron, Fluopyram, Fluoxastrothioconazole, Flusulfamide, Fluxapyroxad, Fenhexamid, Phosphorous acid, Hymexazol, Iprovalicarb, Cyazofamid, Methanesulfocarb, Metrafenone, Pencycuron, Phthalide, Polyoxin, Propamocarb, Pyribencarb, Proquinazid, Pyroquilon, Pyrofenone, Quinoxyfen, Quintozene, Thiadiazinyl, Triazoxide, Tricyclazole, Trifolin, Basiram, Valifenalate, Zoxamide, Mandipropamid, Flubenetam, Isopyrazam, Sedaxane, Pydiflumetofen, 3-difluoromethyl-1-methyl-1H-pyrazole-4-carboxylic acid (3’,4’,5’-trifluoro-biphenyl-2-yl)amide, Isoflupiprazam, Isothianil, Diphenamid, 6-ethyl-5,7-dioxo-pyrrolo[4,5][1,4]dithieno[1,2-c]isothiazole-3-carbonitrile,2-(Difluoromethyl)-N-[3-ethyl-1,1-dimethyl-indan-4-yl]pyridine-3-carboxamide, 4-(2,6-difluorophenyl)-6-methyl-5-phenyl-pyridazine-3-carbonitrile, (R)-3-(difluoromethyl)-1-methyl-N-[1,1,3-trimethylindan-4-yl]pyrazole-4-carboxamide, 4-(2-bromo-4, -(Fluorophenyl)-N-(2-chloro-6-fluorophenyl)-2,5-dimethyl-pyrazole-3-amine, 4-(2-bromo-4-fluorophenyl)-N-(2-chloro-6-fluorophenyl)-1,3-dimethyl-1H-pyrazole-5-amine, fluindopril, kresoxim-methyl (Diahangjuntu), rubenmixenan, dichlobenzothiazole, mandestrobin, 3-(4,4-difluoro-3,4-dihydro-3,3-dimethylisoquinolin-1-yl)quinolone, 2-[2-fluoro-6-[(8-fluoro-2-methyl-3-quinolyl)oxy]phenyl]propan-2-ol, oxathiapiprolin, tert-butyl, N-[6-[[[(1-methyltetrazol-5-yl)phenyl-methylidene]amino]oxymethyl]-2-pyridyl]carbamate, pyraclofamid, imidacloprid, tolprocarb, mefenoxazol, ipconazole, 2-(difluoromethyl)-N-[(3R)-3-ethyl-1,1-dimethyl-indan-4-yl]pyridine-3-carboxamide, N'-(2,5-dimethyl-4-phenoxyphenyl)-N-ethyl-N-methyl-formamidine, N'-[4-(4,5-dichlorothiazol-2-yl)oxy-2,5-dimethylphenyl]-N-ethyl-N-methyl-formamidine, [2-[3-[2-[1-[2-[3,5-bis(difluoromethyl)pyrazol-1-yl]acetyl]-4-piperidyl]thiazol-4-yl]-4,5-dihydroisoxazol-5-yl]-3-chlorophenyl]methanesulfonate, but-3-ynyl, N-[6-[[(Z)-[(1-methyltetrazol-5-yl)-phenyl-methylidene]amino]oxymethyl]-2-pyridyl]carbamate, methyl N-[[5-[4-(2,4-dimethylphenyl)triazol-2-yl]-2-methylphenyl]methyl]carbamate, 3-chloro-6-methyl-5-phenyl-4-(2,4,6-trifluorophenyl)pyridazine, pyridachloromethyl, 3-(difluoromethyl)-1-methyl-N-[1,1,[[3-Trimethylinden-4-yl]pyrazole-4-carboxamide, 1-[2-[[1-(4-chlorophenyl)pyrazol-3-yl]oxymethyl]-3-methyl-phenyl]-4-methyl-tetrazol-5-one, 1-methyl-4-[3-methyl-2-[[2-methyl-4-(3,4,5-trimethylpyrazol-1-yl)phenoxy]methyl]phenyl]tetrazol-5-one, aminopyrifen, ametridazine, amisulbrom, penflufen, (Z,2E)-5-[1-(4-chlorophenyl)pyrazol-3-yl]oxy-2-methoxyimino-N,3-dimethyl-penta-3-enamide, flupyriminoxam, fenpyroxam, metflupyroxam, tebufloquin, iprofenoxine, chinomethionat, isophenamid, ethyl 1-[[4-[[2-(trifluoromethyl)-1,3-dioxolan-2-yl]methoxy]phenyl]methyl]pyrazole-3-carboxylate (which can be prepared by the method described in International Publication No. 2020 / 056090), ethyl 1-[[4-[(Z)-2-ethoxy-3,3,3-trifluoro-prop-1-enoxy]phenyl]methyl]pyrazole-3-carboxylate (which can be prepared by the method described in International Publication No. 2020 / 056090), methyl N-[[4-[1-(4-cyclopropyl-2,6-difluoro-phenyl)pyrazol-4-yl]-2-methyl-phenyl]methyl]carbamate (which can be prepared by the method described in International Publication No. 2020 / 097012), methyl N-[[4-[1-(2,6-difluoro-4-isopropyl-phenyl)pyrazol-4-yl]-2-methyl-phenyl]methyl]carbamate (which can be prepared by the method described in International Publication No. 2020 / 097012), 6-chloro-3-(3-cyclopropyl-2-fluoro-phenoxy)-N-[2-(2,4-dimethylphenyl)-2,2-difluoro-ethyl]-5-methyl-pyridazine-4-carboxamide (which can be prepared by the method described in International Publication No. 2020 / 109391), 6-chloro-N-[2-(2-chloro-4-methyl-phenyl)-2,2-Difluoroethyl]-3-(3-cyclopropyl-2-fluorophenoxy)-5-methyl-pyridazine-4-carboxamide (which can be prepared by the method described in International Publication No. WO2020 / 109391), 6-chloro-3-(3-cyclopropyl-2-fluorophenoxy)-N-[2-(3,4-dimethylphenyl)-2,2-difluoroethyl]-5-methyl-pyridazine-4-carboxamide (which can be prepared by the method described in International Publication No. WO2020 / 109391), N-[2-[2,4-dichlorophenoxy]phenyl]-3-(difluoromethyl)-1-methyl-pyrazole-4-carboxamide, N-[2-[2-chloro-4-(trifluoromethyl)phenoxy]phenyl]-3-(difluoromethyl)-1-methyl-pyrazole-4-carboxamide, benzothiostrobin, fenamacril, 5-amino-1,3,4-thiadiazole-2-thiol zinc salt (2:1), fluopyram, flufenoxdiazin, flutianil, fluopyrimid, pyrapropoyne, picarbutrazox, 2-(difluoromethyl)-N-(3-ethyl-1,1-dimethyl-indan-4-yl)pyridine-3-carboxamide, 2-(difluoromethyl)-N-((3R)-1,1,3-trimethylindan-4-yl)pyridine-3-carboxamide, 4-[[6-[2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(1,2,4-triazol-1-yl)propyl]-3-pyridyl]oxy]benzonitrile, methyltetraprole, 2-(difluoromethyl)-N-((3R)-1,1,3-trimethylindan-4-yl)pyridine-3-carboxamide, α-(1,1-dimethylethyl)-α-[4’-(trifluoromethoxy)[1,1'-Biphenyl]-4-yl]-5-pyrimidinemethanol, fluoxapiprolin, enoxastrobin, methyl (Z)-3-methoxy-2-[2-methyl-5-[4-(trifluoromethyl)triazol-2-yl]phenoxy]prop-2-enoate, methyl (Z)-3-methoxy-2-[2-methyl-5-(4-propyltriazol-2-yl)phenoxy]prop-2-enoate, methyl (Z)-2-[5-(3-isopropylpyrazol-1-yl)-2-methyl-phenoxy]-3-methoxy-prop-2-enoate, methyl (Z)-3-methoxy-2-[2-methyl-5-(3-propylpyrazol-1-yl)phenoxy]prop-2-enoate, methyl (Z)-3-methoxy-2-[2-methyl-5-[3-(trifluoromethyl)pyrazol-1-yl]phenoxy]prop-2-enoate (these compounds can be prepared by the method described in International Publication No. 2020 / 079111), methyl (Z)-2-(5-cyclohexyl-2-methyl-phenoxy)-3-methoxy-prop-2-enoate, methyl (Z)-2-(5-cyclopentyl-2-methyl-phenoxy)-3-methoxy-prop-2-enoate (these compounds can be prepared by the method described in International Publication No. 2020 / 193387), 4-[[6-[2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(1,2,4-triazol-1-yl)propyl]-3-pyridyl]oxy]benzonitrile, 4-[[6-[2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(5-sulfanyl-1,2,4-triazol-1-yl)propyl]-3-pyridyl]oxy]benzonitrile, 4-[[6-[2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(5-thioxo-4H-1,2,(4-triazol-1-yl)propyl]-3-pyridyl]oxy]benzonitrile, trinexapac, kresoxim-methyl, zoxamycin, copper thiodiazole, zinc thiazole, abamectin, iprodione, carboxylamine, N’-[5-bromo-2-methyl-6-[(1S)-1-methyl-2-propoxy-ethoxy]-3-pyridyl]-N-ethyl-N-methylformamidine, N’-[5-bromo-2-methyl-6-[(1R)-1-methyl-2-propoxy-ethoxy]-3-pyridyl]-N-ethyl-N-methyl-formamidine, N’-[5-bromo-2-methyl-6-(1-methyl-2-propoxy-ethoxy)-3-pyridyl]-N-ethyl-N-methyl-formamidine, N’-[5-chloro-2-methyl-6-(1-methyl-2-propoxy-ethoxy)-3-pyridyl]-N-ethyl-N-methyl-formamidine, N’-[5-bromo-2-methyl-6-(1-methyl-2-propoxy-ethoxy)-3-pyridyl]-N-isopropyl-N-methyl-formamidine (these compounds can be prepared by the method described in International Publication No. 2015 / 155075); N’-[5-bromo-2-methyl-6-(2-propoxyethoxy)-3-pyridyl]-N-ethyl-N-methyl-formamidine (this compound can be prepared by the method described in IPCOM000249876D); N-isopropyl-N’-[5-methoxy-2-methyl-4-(2,2,2-trifluoro-1-hydroxy-1-phenylethyl)phenyl]-N-methyl-formamidine, N’-[4-(1-cyclopropyl-2,2,(2-Trifluoro-1-hydroxy-ethyl)-5-methoxy-2-methyl-phenyl]-N-isopropyl-N-methyl-formamidine (these compounds can be prepared by the method described in International Publication No. WO 2018 / 228896); N-ethyl-N'-[5-methoxy-2-methyl-4-[(2-trifluoromethyl)oxetan-2-yl]phenyl]-N-methyl-formamidine, N-ethyl-N'-[5-methoxy-2-methyl-4-[(2-trifluoromethyl)tetrahydrofuran-2-yl]phenyl]-N-methylformamidine (these compounds can be prepared by the method described in International Publication No. WO 2019 / 110427); N-[(1R)-1-benzyl-3-chloro-1-methyl-but-3-enyl]-8-fluoro-quinoline-3-carboxamide, N-[(1S)-1-benzyl-3-chloro-1-methyl-but-3-enyl]-8-fluoro-quinoline-3-carboxamide, N-[(1R)-1-benzyl-3,3,3-trifluoro-1-methyl-propyl]-8-fluoro-quinoline-3-carboxamide, N-[(1S)-1-benzyl-3,3,3-trifluoro-1-methyl-propyl]-8-fluoro-quinoline-3-carboxamide, N-[(1R)-1-benzyl-1,3-dimethyl-butyl]-7,8-difluoro-quinoline-3-carboxamide, N-[(1S)-1-Benzyl-1,3-dimethyl-butyl]-7,8-difluoro-quinoline-3-carboxamide, 8-fluoro-N-[(1R)-1-[(3-fluorophenyl)methyl]-1,3-dimethyl-butyl]quinoline-3-carboxamide, 8-fluoro-N-[(1S)-1-[(3-fluorophenyl)methyl]-1,3-dimethyl-butyl]quinoline-3-carboxamide, N-[(1R)-1-benzyl-1,3-dimethyl-butyl]-8-fluoro-quinoline-3-carboxamide, N-[(1S)-1-benzyl-1,3-dimethyl-butyl]-8-fluoro-quinoline-3-carboxamide, N-((1R)-1-benzyl-3-chloro-1-methyl-but-3-enyl)-8-fluoro-quinoline-3-carboxamide, N-((1S)-1-benzyl-3-chloro-1-methyl-but-3-enyl)-8-fluoro-quinoline-3-carboxamide (these compounds may be prepared by the methods described in International Publication No. 2017 / 153380);1-(6,7-Dimethylpyrazolo[1,5-a]pyridin-3-yl)-4,4,5-trifluoro-3,3-dimethyl-isoquinoline, 1-(6,7-dimethylpyrazolo[1,5-a]pyridin-3-yl)-4,4,6-trifluoro-3,3-dimethyl-isoquinoline, 4,4-difluoro-3,3-dimethyl-1-(6-methylpyrazolo[1,5-a]pyridin-3-yl)isoquinoline, 4,4-difluoro-3,3-dimethyl-1-(7-methylpyrazolo[1,5-a]pyridin-3-yl)isoquinoline, 1-(6-chloro-7-methyl-pyrazolo[1,5-a]pyridin-3-yl)-4,4-difluoro-3,3-dimethyl-isoquinoline (these compounds may be prepared from the methods described in International Publication No. 2017 / 025510): 1-(4,5-dimethylbenzimidazol-1-yl)-4,4,5-trifluoro-3,3-dimethylisoquinoline, 1-(4,5-dimethylbenzimidazol-1-yl)-4,4-difluoro-3,3-dimethylisoquinoline, 6-chloro-4,4-difluoro-3,3-dimethyl-1-(4-methylbenzimidazol-1-yl)isoquinoline, 4,4-difluoro-1-(5-fluoro-4-methyl-benzimidazol-1-yl)-3,3-dimethyl-isoquinoline, 3-(4,4-difluoro-3,3-dimethyl-1-isoquinolyl)-7,8-dihydro-6H-cyclopenta[e]benzimidazole (these compounds may be prepared from the methods described in International Publication No. 2016 / 156085);N-Methoxy-N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]cyclopropanecarboxamide, N,2-dimethoxy-N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]propanamide, N-ethyl-2-methyl-N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]propanamide, 1-methoxy-3-methyl-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]urea, 1,3-dimethoxy-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]urea, 3-ethyl-1-methoxy-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]urea, N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]propanamide, 4,4-dimethyl-2-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]isoxazolidin-3-one, 5,5-dimethyl-2-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]isoxazolidin-3-one, ethyl 1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]pyrazole-4-carboxylate, N,N-dimethyl-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]-1,2,4-triazol-3-amine (these compounds can be prepared from the methods described in International Publication Nos. 2017 / 055473, 2017 / 055469, 2017 / 093348 and 2017 / 118689), 2-[6-(4-chlorophenoxy)-2-(trifluoromethyl)-3-pyridyl]-1-(1,2,4-triazol-1-yl)propan-2-ol (this compound can be prepared by the method described in International Publication No. 2017 / 029179);2-[6-(4-Bromophenoxy)-2-(trifluoromethyl)-3-pyridyl]-1-(1,2,4-triazol-1-yl)propan-2-ol (this compound can be prepared by the method described in International Publication No. WO 2017 / 029179); 3-[2-(1-chlorocyclopropyl)-3-(2-fluorophenyl)-2-hydroxy-propyl]imidazole-4-carbonitrile (this compound can be prepared by the method described in International Publication No. WO 2016 / 156290); 3-[2(1-chlorocyclopropyl)-3-(3-chloro-2-fluoro-phenyl)-2-hydroxy-propyl]imidazole-4-carbonitrile (this compound can be prepared by the method described in International Publication No. WO 2016 / 156290); (4-phenoxyphenyl)methyl 2-amino-6-methyl-pyridine-3-carboxylate (this compound can be prepared from the method described in International Publication No. WO 2014 / 006945) 2,6-dimethyl-1H,5H-[1,4]dithiino[2,3-c:5,6-c’]dipyrrole-1,3,5,7(2H,6H)-tetrone (this compound can be prepared by the method described in International Publication No. WO 2011 / 138281); N-methyl-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzenesulfonamide; N-methyl-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide; (Z,2E)-5-[1-(2,4-dichlorophenyl)pyrazol-3-yl]oxy-2-methoxyimino-N,3-dimethyl-penta-3-enamide (this compound can be prepared by the method described in International Publication No. WO 2018 / 153707); N’-(2-chloro-5-methyl-4-phenoxy-phenyl)-N-ethyl-N-methyl-formamidine; N’-[2-chloro-4-(2-fluorophenoxy)-5-methyl-phenyl]-N-ethyl-N-methyl-formamidine (this compound can be prepared from the method described in International Publication No. WO 2016 / 202742);2-(Difluoromethyl)-N-[(3S)-3-ethyl-1,1-dimethyl-inden-4-yl]pyridine-3-carboxamide (this compound can be prepared by the method described in International Publication No. WO 2014 / 095675); (5-methyl-2-pyridyl)-[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methanone, (3-methylisoxazol-5-yl)-[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methanone (these compounds can be prepared by the method described in International Publication No. WO 2017 / 220485); 2-oxo-N-propyl-2-[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]acetamide (this compound can be prepared by the method described in International Publication No. WO 2018 / 065414); ethyl 1-[[5-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]-2-thienyl]methyl]pyrazole-4-carboxylate (this compound can be prepared by the method described in International Publication No. WO 2018 / 158365); 2,2-difluoro-N-methyl-2-[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]acetamide, N-[(E)-methoxyiminomethyl]-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide, N-[(Z)-methoxyiminomethyl]-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide, N-[N-methoxy-C-methylcarbonimidoyl]-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide (these compounds can be prepared by the method described in International Publication No. WO 2018 / 202428).;

[0096] In particular, the following fungicide mixing partners are preferred: - A strobilurin fungicide selected from the group consisting of azoxystrobin, dimoxystrobin, fluoxastrobin, kresoxim-methyl, metominostrobin, orysastrobin, picoxystrobin, pyraclostrobin, and trifloxystrobin; - An azole fungicide selected from the group consisting of azaconazole, bromoconazole, cyproconazole, difenoconazole, diniconazole, diniconazole-M, epoxyconazole, fenbuconazole, fluquinconazole, flusilazole, flutriafol, hexaconazole, imazalil, imibenconazole, ipconazole, metconazole, microbutanil, oxiconazole, pefurazoate, penconazole, prochloraz, propiconazole, prothioconazole,simeconazole, tebuconazole, tetraconazole, triadimefon, triadimenol, triflumizole, triticonazole, diclobutrazole, etaconazole, fluconazole, fluconazole-cis, and quinazoline; - A morpholine fungicide selected from the group consisting of aldimorph, dodemorph, fenpropimorph, tridemorph, fenpropidin, spiroxamine, and piperalin; - An anilino-pyrimidine fungicide selected from the group consisting of cyprodinil, mepanipyrim, and pyrimethanil; and / or - Fungicides selected from the group consisting of benalaxyl, benalaxyl-M, benomyl, bitertanol, boscalid, captan, carboxin, carpropamid, chlorothalonil, copper, cyazofamid, cymoxanil, diethofencarb, dithianon, famoxadone, fenamidone, fenhexamid, phenoxycarb, fenpiclonil, fluazinam, fluazinam, fludioxonil, flutolanil, folpet, guazatine, hymexazol, iprodione, lufenuron, mancozeb, metalaxyl, mefenoxam, metrafenone, nuarimol, paclobutrazol, penthiopyrad, procymidone, proquinazid, pyroquilon, quinoxyfen, quinoxyfen, and 3-(difluoromethyl)-N-methoxy-1-methyl-N-[1-methyl-2-(2,4,6-trichlorophenyl)ethyl]pyrazole-4-carboxamide, silthiopham, sulfur, thiabendazole, thiram, triazoxide, tricyclazole, isopyrazam, sedaxane, fluxapyroxad, solatenol, and 3-(difluoromethyl)-N-methoxy-1-methyl-N-[1-methyl-2-(2,4,6-trichlorophenyl)ethyl]pyrazole-4-carboxamide.

[0097] Even more preferably, the polymorph of the present invention is combined with strobilurin or azole.

[0098] Compositions comprising the polymorph of the present invention and another fungicide are explicitly disclosed above, but those skilled in the art will understand that the present invention extends to ternary and further multiple combinations including the above binary mixtures.

[0099] To avoid misunderstanding, even if not explicitly stated above, the mixing partner may be in the form of any suitable agriculturally acceptable ester or salt, as described, for example, in The Pesticide Manual, Nineteenth Edition, British Crop Protection Council 2021.

[0100] The present invention will now be described by the following non-limiting examples and figures.

Brief Description of the Drawings

[0101]

Figure 1

Figure 2

Figure 3

Figure 4

Figure 5

Figure 6

MODE FOR CARRYING OUT THE INVENTION

[0102] Examples 1. Preparation of Polymorph The industrial compound of Formula I used for the preparation of the polymorph according to the present invention is a racemic mixture of a compound of Formula I (3-difluoromethyl-1-methyl-1H-pyrazole-4-carboxylic acid (9-dichloromethylene-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl)-amide) with a purity of 99.0%, prepared as described in Example P11 of International Publication No. 2012 / 101139.

[0103] Xylene (580 g) was added to a 1000 mL jacketed crystallization vessel, and the stirring speed was set to 100 rpm and heated to 40 °C. The industrial compound of formula I (30 g) was added slowly, and the mixture was stirred at 40 °C for 30 minutes until only a small amount of solid remained (indicating that saturation had been achieved). The mixture was then heated to 45 °C to dissolve it completely and filtered at a high temperature (45 °C) into four preheated glass bottles, each equipped with a magnetic stirrer, through a preheated funnel equipped with a paper filter (type 1). While stirring the solution, more specifically while gently (magnetically) stirring, it was slowly cooled to room temperature (20 °C), and the resulting suspension was maintained at room temperature for 4 weeks while stirring, more specifically while gently (magnetically) stirring. The suspension was filtered, and the solid was analyzed to confirm the formation of the desired polymorph (form B) according to the present invention.

[0104] 2. Analysis of Polymorphs After preparation by the method detailed above, the sample was subjected to analysis by powder X-ray diffraction, and / or single-crystal X-ray diffraction, and / or differential scanning calorimetry (DSC), and / or near-infrared spectroscopy, and / or mid-infrared spectroscopy.

[0105] Powder X-ray diffraction analysis of the solid material was performed using a Bruker D2 Phaser powder diffractometer at room temperature (20 °C) and a relative humidity of more than 40%. The sample was attached to a standard PMMA sample holder and flattened. The sample holder was rotated, and X-rays were collected from 3.5 to 44° 2θ with a step size of 0.02°, and incident X-rays with a wavelength of 1.5406 Å were collected. The powder X-ray diffraction pattern of the crystalline polymorph (form B) according to the present invention is shown in Figure 1, and the powder X-ray diffraction pattern of the crystalline polymorph (form A) according to the prior art is shown in Figure 6.

[0106] Single crystal strength data were collected on a Rigaku Supernova diffractometer equipped with a graphite monochromator using CuKα radiation (λ = 1.54056 Å). For data collection, the crystal was mounted in NVH oil at -173 °C. The data were solved using the CRYSTALS software package and the results are summarized in Table 2 (unit cell parameters). The X-ray diffraction pattern calculated from the unit cell parameters of the crystal polymorph (Form B) is shown in Figure 2.

[0107] DSC was performed using a Mettler Toledo DSC1 with a standard 40 μL aluminum sample holder with a pierced lid (to allow the escape of gases formed during heating of the sample) at a heating rate of 10 °C / min from 30 to 200 °C. The DSC trace of the crystal polymorph (Form B) according to the present invention is shown in Figure 3.

[0108] Near-infrared spectroscopy was performed on a Bruker MPA1 spectrometer at room temperature (25 °C) using an integrating sphere from 3,500 to 12,500 cm -1 The sample (as received) was transferred to a glass vial. Sufficient sample was used to ensure that all light sources were reflected back to the detector. The near-infrared spectra of the crystal polymorph (Form B) according to the present invention and the crystal polymorph (Form A) according to the prior art are shown in Figure 4.

[0109] Mid-infrared spectroscopy was performed on a Bruker Alpha II spectrometer from 400 to 4,000 cm without sample preparation. Alpha II (FTIR) has an anvil head that presses the sample against a diamond window for analysis. The mid-infrared spectra of the crystal polymorph (Form B) according to the present invention and the crystal polymorph (Form A) according to the prior art are shown in Figure 5. -1

[0110] 3. Experiments To demonstrate the advantages of the crystal polymorphs according to the present invention, the following experiments were conducted.

[0111] 3.1. Seed Formation ​Solid seed B was prepared according to the polymorph preparation of the present invention described above (see item "1. Preparation of polymorphs").

[0112] The powder X-ray diffraction pattern is shown in Figure 6, and solid seed A was prepared according to International Publication No. 2012 / 101139 (Example P11), which is related to anhydrous Form 1 described in International Publication No. 2015 / 128322. The solid seed A (i.e., anhydrous Form 1) can also be prepared according to International Publication No. 2011 / 131544 (step f of the preparation example), International Publication No. 2011 / 131545 (step g of the preparation example), International Publication No. 2011 / 131546 (step d of the preparation example), or the specification of US Patent Application Publication No. 2012 / 136162 (Example P6 or Example P7).

[0113] 3.2. Seed Process Xylene (774 g) and the industrial compound of formula I (125 g) were added to a 1000 ml jacketed vessel equipped with an anchor stirrer (stirring speed: 150 rpm) and heated to 75 °C until all solids were dissolved.

[0114] After cooling the solution to 50 °C (seed temperature), solid seed B (2.0 g) or solid seed A (2.0 g) was added. The suspension was held at 50 °C for 60 minutes and then cooled to 0 °C over 20 hours (a linear cooling gradient from 50 °C to 0 °C over 20 hours). For specific cake resistance measurement, the suspension was discharged into a filtration unit.

[0115] 3.3. Filtration Experiment In the first part, the suspension was charged into a filtration unit equipped with a 20 μm polytetrafluoroethylene filter with a diameter of 5 cm. The device was pressurized (+0.5 barg gauge (barg)) and filtration was started. When the surface of the cake was exposed, filtration was terminated, the filtrate was refilled into the container and cooled to 0 °C. In the second part, filtration was subsequently repeated at a pressure of +0.5 barg. The final product was dried under vacuum (1 - 10 mbar) at 57 °C to obtain polymorph B or A.

[0116] Regarding filtration, the first run establishes a cake on the filter and enables the evaluation of the resistance of the filter medium (cloth). Subsequent runs enable the calculation of a specific cake resistance. The required data are pressure, filtrate viscosity (0.75 mPa·s), the amount of filtrate collected over time, and the final cake height after filtration.

[0117] The following Tables 3 and 4 summarize the results obtained for the second part of each experiment in which the specific cake resistance is calculated. More specifically, Table 3 (Example 1) is according to the present invention (crystals of Form B), the cake height is 0.100 m, and Table 4 (Example 2) is a comparative example (crystals of Form A), the cake height is 0.199 m. All experiments are carried out in the same manner except for the solid (B or A) used.

[0118]

Table 3

[0119]

Table 4

[0120] The cloth resistance for both Examples 1 and 2 is 1.14×10 10 m -1 is.

[0121] The specific cake resistance r ケーキ can be calculated using the following equation.

Equation

Equation

[0122] Summarize the compressibility data described by the above formula in Table 5.

[0123]

Table 5

[0124] From the results in Table 5, the cake obtained from Example 1 according to the present invention has a specific cake resistance that is at least 20 times lower than that of the cake obtained from Example 2. As a result, filtration with polymorph B is faster than filtration with polymorph A. This advantage is a significant improvement during the filtration process of the compound of formula I according to the present invention, especially in terms of shortening the filtration time.

[0125] Although the present invention has been described with reference to its preferred embodiments and examples, the scope of the present invention is not limited only to the described embodiments. As will be apparent to those skilled in the art, changes and modifications to the present invention described above can be made without departing from the spirit and scope of the present invention as defined and limited by the appended claims. All publications cited herein are hereby incorporated by reference in their entirety for all purposes to the same extent as if each individual publication had been specifically and individually indicated to be incorporated by reference.

Claims

1. Formula I: 【Chemistry 1】 A crystalline polymorph of the compound having a powder X-ray diffraction pattern that includes at least three 2θ angular values ​​selected from the group consisting of 7.2±0.2°, 10.8±0.2°, 13.8±0.2°, 14.4±0.2°, 14.8±0.2°, 15.9±0.2°, 16.4±0.2°, 19.9±0.2°, 20.7±0.2°, 22.2±0.2°, 22.6±0.2°, 23.9±0.2°, 24.6±0.2°, 26.0±0.2°, 26.3±0.2°, 27.5±0.2°, 30.0±0.2°, 32.0±0.2°, and 32.7±0.2°.

2. The crystal polymorph according to claim 1, characterized in that the powder X-ray diffraction pattern includes at least six 2θ angle values ​​selected from the group consisting of 7.2±0.2°, 10.8±0.2°, 13.8±0.2°, 14.4±0.2°, 14.8±0.2°, 15.9±0.2°, 16.4±0.2°, 19.9±0.2°, 20.7±0.2°, 22.2±0.2°, 22.6±0.2°, 23.9±0.2°, 24.6±0.2°, 26.0±0.2°, 26.3±0.2°, 27.5±0.2°, 30.0±0.2°, 32.0±0.2°, and 32.7±0.2°.

3. The crystalline polymorph according to claim 1, characterized in that the powder X-ray diffraction pattern includes at least the following 2θ angle values: 7.2±0.2°, 10.8±0.2°, 13.8±0.2°, 14.4±0.2°, 14.8±0.2°, 16.4±0.2°, 20.7±0.2°, 22.2±0.2°, 24.6±0.2°, and 26.0±0.2°.

4. The following lattice parameters: a = 8.0 ± 0.1 Å, b = 14.0 ± 0.1 Å, c = 17.0 ± 0.1 Å, α = 70.2 ± 0.2°, β = 84.1 ± 0.2°, γ = 74.4 ± 0.2°, and volume = 1724 ± 20 Å 3 The crystalline polymorph according to claim 1, characterized by having the above characteristics.

5. The crystalline polymorph according to claim 1, characterized in that it has a melting point in the range of 153°C to 156°C (peak position), preferably in the range of 154°C to 155°C (peak position).

6. A pesticide composition comprising a crystalline polymorph according to any one of claims 1 to 5 and at least one agriculturally acceptable carrier or diluent.

7. The composition according to claim 6, characterized by comprising at least one further fungicide.

8. The composition according to claim 7, characterized in that the further fungicide is strobilurin or azole.

9. The composition according to claim 6, further comprising at least one insecticide and / or at least one nematicidal agent.

10. A method for preventing or controlling fungal infections of plants or plant propagation materials, comprising treating plants or plant propagation materials with the pesticide composition described in claim 6.

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