Use of a manganese-containing compound for reducing uric acid levels in a mammalian subject

JP2025524726A5Pending Publication Date: 2026-06-26SHANGHAI SHIQU PHARM TECH CO LTD

Patent Information

Authority / Receiving Office
JP · JP
Patent Type
Applications
Current Assignee / Owner
SHANGHAI SHIQU PHARM TECH CO LTD
Filing Date
2023-07-14
Publication Date
2026-06-26

AI Technical Summary

Technical Problem

Current treatments for hyperuricemia and gout are inadequate in reducing uric acid levels and are often accompanied by harmful side effects, while existing drugs that act locally in the digestive tract do not effectively lower systemic uric acid levels.

Method used

The use of insoluble manganese-containing compounds, such as manganese oxide, to adsorb and remove uric acid in the gastrointestinal tract, which are not affected by digestive fluids and can be administered at high doses without causing unacceptable side effects.

Benefits of technology

Insoluble manganese-containing compounds effectively reduce uric acid levels in the blood and gastrointestinal tract, providing a safe and complementary approach to existing treatments by maintaining uric acid levels within the normal range and preventing associated disorders.

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Abstract

Use of a manganese-containing compound for reducing uric acid levels in a mammalian subject. In particular, the present invention relates to the use of an insoluble manganese-containing compound in the preparation of a medicament for preventing and / or treating an increase in the level of uric acid in the blood and / or gastrointestinal tract of a mammalian subject, or a disease or condition associated with an increase in the level of uric acid in the blood and / or gastrointestinal tract, a pharmaceutical composition, a kit for such use, and a method for preventing and / or treating related diseases or conditions.
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