Aqueous liquid

JP2026096220APending Publication Date: 2026-06-15SENJU PHARMA CO LTD

Patent Information

Authority / Receiving Office
JP · JP
Patent Type
Applications
Current Assignee / Owner
SENJU PHARMA CO LTD
Filing Date
2024-12-03
Publication Date
2026-06-15

AI Technical Summary

Technical Problem

Existing aqueous solutions containing epinastine and/or its salts exhibit pH instability under light or heat exposure, which is not adequately addressed by conventional formulation technologies.

Method used

An aqueous solution comprising epinastine and/or its salt and monoethanolamine and/or its salt, with a pH of 7.5 or higher, which enhances pH stability against light and heat exposure.

🎯Benefits of technology

The solution effectively suppresses pH changes due to light or heat exposure, maintaining stability within a pH range of 0.4 or less, even after exposure to high illuminance or storage at elevated temperatures.

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Abstract

The object of the present invention is to provide a liquid formulation technology relating to an aqueous liquid formulation containing epinastine and / or a salt thereof. [Solution] An aqueous solution comprising epinastine and / or a salt thereof, and monoethanolamine and / or a salt thereof, with a pH of 7.5 or higher.
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