Method for preparing a composition containing unfolding protein
A simplified method using a dry composition of polypeptides and specific salts forms biologically active complexes, addressing inefficiencies in existing methods by maintaining activity and reducing complexity and cost.
Patent Information
- Authority / Receiving Office
- JP · JP
- Patent Type
- Applications
- Filing Date
- 2026-04-01
- Publication Date
- 2026-07-07
AI Technical Summary
Existing methods for preparing biologically active complexes, such as HAMLET, are cumbersome and require freeze-drying, making them inefficient for storage and transportation, and there is a need for a simpler and more economical method that maintains biological activity.
A method involving a dry composition of polypeptides, fatty acids or their salts, and a buffering component of specific salts like sodium chloride and disodium phosphate, which is combined without water, allowing for easy reconstitution to form biologically active complexes.
The method enables the production of biologically active complexes that maintain activity levels comparable to freeze-dried counterparts, is simpler and more economical, and can be prepared without specialized equipment, suitable for various environments.
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