Composition

Abstract

The present invention provides an oral liquid composition that is rich in collagen and has a reduced characteristic collagen odor. [Solution] According to one aspect of the present invention, an oral liquid composition is provided, comprising collagen in an amount of 6 g / 100 ml or more and less than 20 g / 100 ml, and one or more imidazole dipeptides selected from the group consisting of anserine, carnosine, balenine, homoanserine, and homocarnosine in an amount of more than 0.25 g / 100 ml and less than 2.0 g / 100 ml.

Description

Technical Field

[0006] , , ,

[0001] The present invention relates to an oral liquid composition containing collagen and imidazole dipeptide, a method for producing the same, and a method for improving the taste quality of the collagen-containing oral liquid composition. and the like.

Background Art

[0002] Collagen has originally been a raw material widely used in the food field, but has recently attracted attention due to the increasing health consciousness. Collagen is an animal protein and is the main component of the dermis and connective tissue. Therefore, products utilizing collagen have also been developed in the medical field, the cosmetic field, and the health food field. For example, Japanese Patent No. 6956846 (Patent Document 1) describes a lumbago-improving agent and a trunk muscle strength-improving agent containing type II collagen, proteoglycan, hyaluronic acid, and imidazole dipeptide.

[0003]

[0004] In addition, the popularity of chicken extract beverages rich in collagen, mainly in Asia, is increasing.

Prior Art Documents

[0005]

Patent Documents

Patent Document 1

Summary of the Invention

[0006]

Problems to be Solved by the Invention

[0007] [Means for solving the problem]

[0007] The higher the collagen content in a beverage, the stronger the characteristic odor (fishy smell) of collagen becomes. Although this is an undesirable tendency, the inventors have found that even if collagen is contained at a high concentration, anthracite Select from the group consisting of phosphorus, carnosine, balenine, homoanserine, and homocarnosine. By containing one or more imidazole dipeptides at a predetermined concentration, collagen-specific properties are achieved. We have found that it is possible to reduce the odor. This invention is based on this finding. be.

[0008] The present invention provides the following oral liquid compositions and a method for producing said oral liquid compositions. [1] An oral liquid composition, Collagen that is 6g / 100ml or more and less than 20g / 100ml Anserine and calcium carbonate in amounts exceeding 0.25g / 100ml and less than 2.0g / 100ml One selected from the group consisting of nosine, balenine, homoanserine, and homocarnosine. The above imidazole dipeptides and A composition containing the following: [2] The content of one or more of the aforementioned imidazole dipeptides is 0.3 to 1.6 g / 100 ml. The composition described in [1]. [3] The content of one or more of the aforementioned imidazole dipeptides is 0.35 to 1.4 g / 100 ml. A composition as described in [1]. [4] The collagen content is 6-11g / 100ml, The content of one or more of the aforementioned imidazole dipeptides is 0.5 to 1.3 g / 100 ml. The composition described in [1]. [5] The collagen content is 6 to 10 g / 100 ml, the content of the above-mentioned one or more imidazole dipeptides is 0.6 to 1.25 g / 100 ml, and the composition according to [1]. [6] When the collagen content is Y (g / 100 ml) and the total content of carnosine and anserine is X (g / 100 ml), the formula (1): Y≧-17.705X+16.705 (1) is satisfied, and the composition according to any one of [3] to [5]. [7] The composition according to any one of [1] to [6], which contains anserine and carnosine. [8] The composition according to any one of [1] to [7], which contains 50 to 200 mg / 100 mL of sodium. [9] The composition according to any one of [1] to [8], which contains 300 to 900 mg / 100 mL of BCAA.

[10] The composition according to any one of [1] to [9], which is a pouch soup.

[11] A method for improving the taste quality of a collagen-containing oral liquid composition, wherein the amount of collagen contained in the collagen-containing oral liquid composition is 6 g / 100 ml or more, and 0.04 to 0.5 g of anserine, carnosine, balenine, homanserine and homocarnosine selected from the group consisting of one or more imidazole dipeptides is included per 1 g of collagen contained in the collagen-containing oral liquid composition.

[12] The amount of collagen contained in the collagen-containing oral liquid composition is less than 20 g / 100 ml, and the method according to

[11] .

Advantages of the Invention

[0009] According to one aspect of the present invention, a collagen-rich and collagen-specific odor is reduced. A reduced oral liquid composition can be provided. According to a preferred embodiment of the present invention, It is rich in collagen, yet the characteristic odor (fishy smell) of collagen is reduced, and the bitterness is also reduced. A reduced oral liquid composition is provided. [Modes for carrying out the invention]

[0010] The present invention will be described in detail below. The following embodiments are illustrative examples for illustrating the present invention. However, the present invention is not intended to be limited to these embodiments only. The present invention does not deviate from its gist. Unless otherwise specified, it can be implemented in various forms. Furthermore, all documents cited in this specification, as well as published gazettes, patent gazettes, and other patents References shall be incorporated herein by reference.

[0011] 1. Oral liquid composition In one embodiment, the present invention relates to an oral liquid composition comprising collagen and imidazole dipeptide. The present invention provides (hereinafter also referred to as "the oral liquid composition of the present invention").

[0012] In this specification, "oral liquid composition" means a liquid composition that can be taken orally. From highly fluid beverages such as soft drinks or ready-to-drink (RTD) beverages, This includes beverages with relatively low fluidity, such as jelly-like drinks. Furthermore, oral liquid compositions include , compositions that are heated and consumed in a soup-like state, for example, pouch-packaged soup (chicken ed This also includes essences (such as Chicken Essence or DEOC (Drip Essence of Chicken)). In a preferred embodiment of the present invention, the liquid composition is a soup in a pouch.

[0013] An oral liquid composition according to one embodiment of the present invention contains 6 g / 100 ml or more, and 20 g / Collagen in amounts less than 100ml and amounts exceeding 0.25g / 100ml, and 2.0g / 10 From 0 ml of anserine, carnosine, balenine, homoanserine and homocarnosine It contains one or more imidazole dipeptides selected from the group. Hereinafter, the oral Liquid compositions will be described.

[0014] <Collagen> Collagen is one of the proteins that make up the dermis, ligaments, tendons, bones, and cartilage, and is polycrystalline. It is the main component of the extracellular matrix of swarms. Collagen is obtained at the site where it is obtained. Therefore, although it can be classified into several types, the collagen used in this invention is not particularly limited. It will not be done.

[0015] In some embodiments of the present invention, collagen contains collagen peptides. That's also fine. Collagen peptides are formed when collagen is broken down into relatively low molecular weight molecules. Compared to regular collagen, collagen peptides are absorbed into the body when taken orally. It is preferable in that it has high yield. The average molecular weight (Mw) of the collagen peptide is not particularly limited. However, for example, those with a molecular weight of 8,000 or less can be used. The molecular weight of collagen is commercially available. In the case of goods, you should follow the product information provided by the supplier, but in cases where such information is not available... In this case, gel permeation chromatography (GPC: polyethylene glycol) It can be measured using the standard method with PEG standards. Commercially available collagen peptides For example, Rousselot's "Peptan F 2000 HD" (average molecular weight (Mw): 2000 ) are some examples.

[0016] The origin of the collagen is not particularly limited; any collagen that can be used in food and beverages can be used. It is possible. According to some embodiments, collagen derived from chicken or fish Gen is used. Refined collagen may be added separately, or collagen such as chicken extract. It may be included by adjusting the proportion of raw materials containing collagen. The source of collagen is 1 It can be one species or two or more species.

[0017] The amount of collagen contained in the oral liquid composition in some embodiments of the present invention is 6 The amount of collagen should be within this range: g / 100ml or more, and less than 20g / 100ml. Furthermore, by combining it with the imidazole dipeptide described later, an oral liquid composition is obtained. To maintain a high level of collagen content while reducing the characteristic fishy smell of collagen. This can be achieved. It is also expected that the high collagen content will enhance the health benefits, and consumers A high appeal effect is expected against this. Collagen content in a preferred embodiment of the present invention The amounts are 6-19g / 100ml, 6-18g / 100ml, 6-17g / 100ml, 6~16g / 100ml, 6~15g / 100ml, 6~14g / 100ml, 6~13 g / 100ml, 6~12g / 100ml, 6~11g / 100ml, 6~10g / 10 0ml, 6g / 100ml or more, and less than 10g / 100ml, 6-9g / 100ml , 6-8g / 100ml, 6-7g / 100ml, over 6g / 100ml, and 13g Less than 100ml, more than 6g / 100ml, and 12g / 100ml or less, 6g / 100 More than 11g / 100ml and less than or equal to 11g / 100ml, more than 6g / 100ml and 10g / 100ml Less than 1, more than 6g / 100ml, and less than 10g / 100ml, more than 6g / 100ml, or Furthermore, 9g / 100ml or less, more than 6g / 100ml, and 8g / 100ml or less, 6g / Over 100ml, and 7g / 100ml or less, 6.1~13g / 100ml, 6.1g / 100ml or more, and less than 13g / 100ml, 6.1-12g / 100ml, 6.1 ~11g / 100ml, 6.1~10g / 100ml, 6.1g / 100ml or more, and , less than 10g / 100ml, 6.1~9g / 100ml, 6.1~8g / 100ml, 6 0.1-7g / 100ml, 6.2g / 100ml or more, and less than 13g / 100ml, 6.2~12g / 100ml, 6.2~11g / 100ml, 6.2~10g / 100m l, 6.2g / 100ml or more, and less than 10g / 100ml, 6.2~9g / 100 ml, 6.2~8g / 100ml, 6.2~7g / 100ml, 6.5g / 100ml or more Above, and less than 13g / 100ml, 6.5-12g / 100ml, 6.5-11g / 1 00ml, 6.5~10g / 100ml, 6.5g / 100ml or more, and 10g / 1 Less than 00ml, 6.5-9g / 100ml, 6.5-8g / 100ml, 6.5-7g / 100ml, 7g / 100ml or more, and less than 13g / 100ml, 7-12g / 10 0ml, 7-11g / 100ml, 7-10g / 100ml, 7g / 100ml or more, or less than 10g / 100ml, 7-9g / 100ml, 7-8g / 100ml, 8g / 1 00ml or more, and less than 13g / 100ml, 8-12g / 100ml, 8-11g / 100ml, 8-10g / 100ml, 8g / 100ml or more, and 10g / 100ml It may be less than 1 or 8-9g / 100ml. Collagen content is preferable. The recommended amounts are 6-11g / 100ml, 6-10g / 100ml, or 6.1g / 100ml or more. Furthermore, it is less than 10g / 100ml.

[0018] The collagen content is determined by measuring the hydroxyproline contained in the oral liquid composition using an amino acid analyzer. It can be determined by quantitative analysis, but if the content can be calculated from the amount used, then use the amount used. You may also obtain it from there. When measuring with an amino acid analyzer, the measurement conditions should be the standard measurement method of the analyzer. It can be measured. The amino acid analyzer used is a fully automated amino acid analyzer manufactured by JEOL Corporation. (JLC-500 / V2) etc. can be used. The amount of collagen can be calculated from the amount of hydroxyproline. The hydroxyproline coefficient required to extract it depends on the raw material (e.g., chicken, fish, pork, etc.) It can be calculated from the amino acid composition data of collagen, for example, from chicken or pork. If you want to determine the amount of collagen from the amount of hydroxyproline, then the amount of hydroxyproline is related to It can be calculated by multiplying by the number 8.

[0019] <Imidazole dipeptide> Oral liquid compositions in some embodiments of the present invention contain imidazole dipeptides Hmm. Imidazole dipeptides are dipeptides that have a histidine ring containing an imidazole ring as a component. This is a general term for petit de (Nobuya Yanai, Journal of the Japan Society for Food Chemistry and Technology, 2014, Vol. 61, No. 1, p. 45). Here, imidazole is a type of five-membered cyclic aromatic heterocyclic compound, in which the nitrogen atom is These are nitrogen-containing aromatic heterocyclic compounds that occupy the 1st and 3rd positions.

[0020] Surprisingly, the inventors have found that anserine, carnosine, balenine, and homoanserine and one or more imidazole dipeptides selected from the group consisting of homocarnosine When used in oral liquid compositions together with collagen, it effectively eliminates the characteristic odor (fishy smell) of collagen. We found that it could be effectively suppressed. This fishy smell is similar to the smell of trimethylamine. It is also expressed. In a preferred embodiment, by combining it with a predetermined amount of collagen, The distinctive bitterness of dazole dipeptide is also reduced.

[0021] There are various types of imidazole dipeptides, including anserine, carnosine, balenine, It may also contain imidazole dipeptides other than homoanserine and homocarnosine. In some embodiments of the present invention, the oral liquid compositions include anserine and carnosine. It contains one or more imidazole dipeptides selected from the group consisting of the following. Preferred in the present invention The oral liquid composition in the embodiment contains anserine and carnosine.

[0022] Imidazole dipeptide used in oral liquid compositions in some embodiments of the present invention It is obtained by extraction from a material containing imidazole dipeptide (e.g., fish meat) using an aqueous solvent. It may be a natural product or obtained through chemical synthesis, and its origin and raw materials are not particularly restricted. No. Imidazole dipeptides are found in fish meat such as tuna, bonito, and salmon, and beef, for example. It can be obtained from pork and chicken, etc. Mammals such as pigs and cattle have a high amount of carnosine. In aquatic mammals, the ratio of carnosine to balenine is approximately 1:2, while in birds, the ratio of carnosine to balenine is approximately 1:2. The ratio of serine to anserine is 1:3, and it is said that in large fish, it becomes almost entirely anserine. (by Nobuya Yanai, Journal of the Japan Society for Food Chemistry and Technology, 2014, Vol. 61, No. 1, p. 45). In the present invention This allows for the selection of imidazole dipeptide raw materials according to the desired efficacy and application.

[0023] Anserine, carnosine, and other substances contained in oral liquid compositions in some embodiments of the present invention. One or more selected from the group consisting of , balenine, homoanserine, and homocarnosine. The amount of imidazole dipeptide is greater than 0.25 g / 100 ml and 2.0 g / 1 It is less than 00 ml. The oral liquid composition contains anserine, carnosine, balenine, homoan Two or more imidazole dipeptides selected from the group consisting of serine and homocarnosine If thiosulfates are present, the amounts listed here refer to the total amount of those imidazole dipeptides. By setting the content of a predetermined imidazole dipeptide within this range, the collagen-specific properties are achieved. This method reduces the odor (fishy smell) while also reducing the bitterness of the imidazole dipeptide. Therefore, it is possible to provide a liquid composition with excellent taste quality. Preferably, anserine, calcium One selected from the group consisting of nosine, balenine, homoanserine, and homocarnosine. The imidazole dipeptide content is 0.26-1.9g / 100ml, 0.26 ~1.8g / 100ml, 0.26~1.7g / 100ml, 0.26~1.6g / 10 0ml, 0.26~1.5g / 100ml, 0.26~1.4g / 100ml, 0.26 ~1.3g / 100ml, 0.26~1.2g / 100ml, 0.26~1.1g / 10 0ml, 0.26~1.0g / 100ml, 0.26~0.9g / 100ml, 0.26 ~0.8g / 100ml, 0.26~0.7g / 100ml, 0.26~0.6g / 10 0ml、0.3~1.9g / 100ml、0.3~1.8g / 100ml、0.3~1. 7g / 100ml、0.3~1.6g / 100ml、0.3~1.5g / 100ml、0 .3~1.4g / 100ml、0.3~1.3g / 100ml、0.3~1.2g / 10 0ml、0.3~1.1g / 100ml、0.3~1.0g / 100ml、0.3~0. 9g / 100ml、0.3~0.8g / 100ml、0.3~0.7g / 100ml、0 .3~0.6g / 100ml、0.35~1.9g / 100ml、0.35~1.8g / 100ml、0.35~1.7g / 100ml、0.35~1.6g / 100ml、0. 35~1.5g / 100ml、0.35~1.4g / 100ml、0.35~1.3g / 100ml、0.35~1.2g / 100ml、0.35~1.1g / 100ml、0. 35~1.0g / 100ml、0.35~0.9g / 100ml、0.35~0.8g / 100ml、0.35~0.7g / 100ml、0.35~0.6g / 100ml、0. 45~1.9g / 100ml、0.45~1.8g / 100ml、0.45~1.7g / 100ml、0.45~1.6g / 100ml、0.45~1.5g / 100ml、0. 45~1.4g / 100ml、0.45~1.3g / 100ml、0.45~1.2g / 100ml、0.45~1.1g / 100ml、0.45~1.0g / 100ml、0. 45~0.9g / 100ml、0.45~0.8g / 100ml、0.45~0.7g / 100ml、0.45~0.6g / 100ml、0.5~1.9g / 100ml、0.5 ~1.8g / 100ml、0.5~1.7g / 100ml、0.5~1.6g / 100m l、0.5~1.5g / 100ml、0.5~1.4g / 100ml、0.5~1.3g / 100ml, 0.5~1.2g / 100ml, 0.5~1.1g / 100ml, 0.5 ~1.0g / 100ml, 0.5~0.9g / 100ml, 0.5~0.8g / 100m l, 0.5~0.7g / 100ml, 0.5~0.6g / 100ml, 0.6~1.9g / 100ml, 0.6~1.8g / 100ml, 0.6~1.7g / 100ml, 0.6 ~1.6g / 100ml, 0.6~1.5g / 100ml, 0.6~1.4g / 100m l, 0.6~1.25g / 100ml, 0.6~1.3g / 100ml, 0.6~1.2 g / 100ml, 0.6~1.1g / 100ml, 0.6~1.0g / 100ml, 0. 6-0.9g / 100ml, 0.6-0.8g / 100ml, or 0.6-0.7g / 1 It may be 00 ml. More preferably, the imidazole dipeptide content is 0.3 It may be ~1.6g / 100ml or 0.35~1.4g / 100ml. In other embodiments, the imidazole dipeptide content is 0.5 g / 100 ml More than 1.0g / 100ml and less than 1.0g / 100ml, 0.5g / 100ml or more and 1.0g / 100ml 1 or less, 0.6g / 100ml or more and 1.3g / 100ml or less, or 0.6g / 10 It may be 0 ml or more and 1.25 g / 100 ml or less.

[0024] Anserine and carnosine contained in oral liquid compositions in some embodiments of the present invention The total amount of n is greater than 0.25g / 100ml and less than 2.0g / 100ml. By keeping the total content of anserine and carnosine within this range, the characteristic odor of collagen is eliminated. Because it can reduce the (fishy smell) while also reducing the bitterness of anserine and carnosine, This can provide a liquid composition with excellent flavor quality. Preferably, anserine and carnosine. The total content is 0.26-1.9g / 100ml, 0.26-1.8g / 100ml, 0.26~1.7g / 100ml, 0.26~1.6g / 100ml, 0.26~1.5 g / 100ml, 0.26~1.4g / 100ml, 0.26~1.3g / 100ml, 0.26~1.2g / 100ml, 0.26~1.1g / 100ml, 0.26~1.0 g / 100ml, 0.26~0.9g / 100ml, 0.26~0.8g / 100ml, 0.26~0.7g / 100ml, 0.26~0.6g / 100ml, 0.3~1.9g / 100ml, 0.3~1.8g / 100ml, 0.3~1.7g / 100ml, 0.3 ~1.6g / 100ml, 0.3~1.5g / 100ml, 0.3~1.4g / 100m l, 0.3~1.3g / 100ml, 0.3~1.2g / 100ml, 0.3~1.1g / 100ml, 0.3~1.0g / 100ml, 0.3~0.9g / 100ml, 0.3 ~0.8g / 100ml, 0.3~0.7g / 100ml, 0.3~0.6g / 100m l, 0.35~1.9g / 100ml, 0.35~1.8g / 100ml, 0.35~1 .7g / 100ml, 0.35~1.6g / 100ml, 0.35~1.5g / 100m l, 0.35~1.4g / 100ml, 0.35~1.3g / 100ml, 0.35~1 .2g / 100ml, 0.35~1.1g / 100ml, 0.35~1.0g / 100m l, 0.35~0.9g / 100ml, 0.35~0.8g / 100ml, 0.35~0 .7g / 100ml, 0.35~0.6g / 100ml, 0.45~1.9g / 100m l, 0.45~1.8g / 100ml, 0.45~1.7g / 100ml, 0.45~1 .6g / 100ml, 0.45~1.5g / 100ml, 0.45~1.4g / 100m l, 0.45~1.3g / 100ml, 0.45~1.2g / 100ml, 0.45~1 .1g / 100ml, 0.45~1.0g / 100ml, 0.45~0.9g / 100m l, 0.45~0.8g / 100ml, 0.45~0.7g / 100ml, 0.45~0 .6g / 100ml, 0.5~1.9g / 100ml, 0.5~1.8g / 100ml, 0.5~1.7g / 100ml, 0.5~1.6g / 100ml, 0.5~1.5g / 1 00ml, 0.5~1.4g / 100ml, 0.5~1.3g / 100ml, 0.5~1 .2g / 100ml, 0.5~1.1g / 100ml, 0.5~1.0g / 100ml, 0.5~0.9g / 100ml, 0.5~0.8g / 100ml, 0.5~0.7g / 1 00ml, 0.5~0.6g / 100ml, 0.6~1.9g / 100ml, 0.6~1 .8g / 100ml, 0.6~1.7g / 100ml, 0.6~1.6g / 100ml, 0.6~1.5g / 100ml, 0.6~1.4g / 100ml, 0.6~1.25g / 100ml, 0.6~1.3g / 100ml, 0.6~1.2g / 100ml, 0.6~ 1.1g / 100ml, 0.6~1.0g / 100ml, 0.6~0.9g / 100ml It may also be 0.6-0.8g / 100ml or 0.6-0.7g / 100ml. More preferably, the total content of anserine and carnosine is 0.3 to 1.6 g / 100 ml. It may be 1 or 0.35-1.4 g / 100 ml. Alternatively, in other embodiments... Furthermore, the total content of anserine and carnosine is 0.5g / 100ml or more and 1.0g Less than 100ml, 0.5g / 100ml or more and 1.0g / 100ml or less, 0.6g / 100ml or more and 1.3g / 100ml or less or 0.6g / 100ml or more and 1 It may be 0.25g / 100ml or less.

[0025] The imidazole dipeptide content should be measured by high-performance liquid chromatography (HPLC). It can be calculated using the formula, but if the content can be calculated from the blending amount, it can also be calculated from the blending amount. The measurement conditions when measuring with HPLC can be determined using the standard measurement method of the analyzer. When measuring with HPLC, an ion exchange column (for example, 300SCX (dimensions: 4.6)) is used. A 250mm x 250mm particle size (5μm) can be used.

[0026] In some embodiments of the present invention, in oral liquid compositions, the collagen content and A group consisting of anserine, carnosine, balenine, homoanserine, and homocarnosine. The ratio of the content of one or more imidazole dipeptides selected from (collagen / imidazole) The dipeptides are not particularly limited, but for example, 3-50, 3-40, 3-30, 3-25, 3-20, 3-15, 3-10, 4-50, 4-40, 4-30, 4-25, 4-20, 4-15, 4-10, 5-50, 5-40, 5-30, 5-25, 5-20, It can be 5-15 or 5-10.

[0027] In some embodiments of the present invention, in oral liquid compositions, the collagen content and Ratio of total anserine and carnosine content (collagen / [anserine + carnosine]) ) is not particularly limited, but for example, 3-50, 3-40, 3-30, 3-25, 3- 20, 3-15, 3-10, 4-50, 4-40, 4-30, 4-25, 4-20, 4- 15, 4-10, 5-50, 5-40, 5-30, 5-25, 5-20, 5-15 or 5 to 10 is also acceptable.

[0028] An oral liquid composition in a preferred embodiment of the present invention has a collagen content of 6 to 1 It is 1g / 100ml and contains anserine, carnosine, balenine, homoanserine and ho The content of one or more imidazole dipeptides selected from the group consisting of mocarnosine is 0 It is an oral liquid composition containing 0.5 to 1.3 g / 100 ml. Another preferred embodiment of the present invention The oral liquid composition in the administration form has a collagen content of 6-10g / 100ml. a group consisting of anserine, carnosine, balenine, homoanserine, and homocarnosine. The content of one or more imidazole dipeptides selected from the above is 0.6-1.25 g / 10 It is an oral liquid composition with a volume of 0 ml.

[0029] An oral liquid composition in yet another preferred embodiment of the present invention contains collagen The amount is 6-11g / 100ml, and the total content of anserine and carnosine is 0.5-1 This is an oral liquid composition with a concentration of 0.3 g / 100 ml. Another preferred embodiment of the present invention The oral liquid composition in form has a collagen content of 6-10 g / 100 ml. Oral solution with a total content of anserine and carnosine of 0.6-1.25 g / 100 ml. It is a body composition.

[0030] In some embodiments of the present invention, the oral liquid composition has a collagen content of Y(g) Let X be the total amount of carnosine and anserine (g / 100ml). In this case, equation (1): Y≧-17.705X+16.705 (1) The following conditions are met. Equation (1) is used in Examples 1-14, 1-33 and 1-35 in Example 1 described below. This is based on the equation of the linear approximation curve derived from the data. By being within the upper range, the characteristic odor (fishy smell) of collagen in oral liquid compositions is reduced. Furthermore, it is preferable in that bitterness is reduced.

[0031] <Chicken extract> In some embodiments of the present invention, the oral liquid composition contains collagen and anserine, Selected from the group consisting of lunosine, balenine, homoanserine, and homocarnosine. Chicken extract may be included as a raw material containing more than one species of imidazole dipeptide. Chicken extract is obtained by hot water extraction or other methods using chicken meat, bones, legs, and skin as raw materials. It is a component that is derived from the group consisting of carnosine and anserine. It contains one or more selected imidazole dipeptides.

[0032] Chicken extract used in oral liquid compositions in some embodiments of the present invention is carnosi A salt of one or more imidazole dipeptides selected from the group consisting of n and anserine If included, the imidazole dipeptide content in chicken extract is... It refers to the total amount of dol and its salts.

[0033] Examples of imidazole dipeptide salts include, but are not limited to, sodium, lithium, and calcium. Hydroxides, carbonates, and heavy carbons of aluminum, magnesium, and ammonia. Inorganic salts such as acid salts; as well as methylamine, dimethylamine and trimethylamine Mono-, di-, or tri-alkylamine salts, mono-, di-, or tri-hydr Organic salts such as roxyalkylamine salts, guanidine salts, and N-methylglucosamine salts Salts containing these are examples.

[0034] When chicken extract is used in the oral liquid composition in some embodiments of the present invention, You may use an extract obtained by heating chicken or other ingredients in a liquid, or you may use commercially available chicken extract. Kisses may be used. The ingredients for the chicken extract may include chicken bones, cartilage, legs, etc.

[0035] A commercially available chicken extract product is "Brand's Essence of Chicken (BEC) (Suntory Beverage)." (Manufactured by age & Food Asia Co., Ltd.), "Scotch® Essence of Chicken (Scotch Industries, Thailand)" (Manufactured by Western Corporation), Quaker Essence of Chicken (Manufactured by Standard Foods Corporation of Taiwan) (Manufactured by) "SWANSON (registered trademark) Chicken stock and broth (Campbell Soup Company)" "Drip Chicken Essence (manufactured by Eu Yan Sang International, Singapore)" "Boned Chicken Tonic (made by Eu Yan Sang International of Singapore)", "Boi Examples include "led Essence of Chicken (made by Lao Xie Zhen, Taiwan)." Any commercially available product can be used, but Brand's Essence of Chicken (BEC) is recommended. It is preferable to use it.

[0036] Chicken extract used in oral liquid compositions in some embodiments of the present invention is chicken When manufactured by hot water extraction of meat, chicken bones, cartilage, legs, etc. (hereinafter referred to as "chicken meat, etc."), generally It can be manufactured by the methods used. For example, chicken meat, etc., can be heated in a solvent at high temperature under normal pressure or by heating. Chicken extract can be produced by processing under pressure. This involves removing fats and cholesterol after crude extraction with a solvent, and then removing excess solvent. The concentration can be increased by using [this method].

[0037] In this specification, chicken extract refers to the liquid extract obtained by the above method, and liquid This includes diluted solutions, concentrates, or dried powders of extracts, and their purified products. For example, the purified product may be obtained by ultrafiltration, membrane treatment, liquid separation, resin treatment, etc., of chicken extract. This can be obtained by applying image processing and increasing its purity.

[0038] Amount of chicken extract in oral liquid composition in some embodiments of the present invention (solid fractionation) The calculation is not particularly limited as long as the amounts of collagen and imidazole dipeptide are within a predetermined range. However, it is preferable that it be 5% to 25% by weight. In a preferred embodiment of the present invention The amount of chicken extract (in terms of solid content) is 8% to 16% by weight, and 10% to 14% by weight. Alternatively, 11% to 13% by weight is also acceptable.

[0039] <Other ingredients and properties> Oral liquid compositions according to some embodiments of the present invention contain water. Water is not particularly limited. Any water can be used as long as it does not negatively affect the flavor, such as tap water or deionized water. Examples include soft water, distilled water, carbonated water, reverse osmosis water (RO water), activated carbon treated water, purified water, and desalinated water. It can be done.

[0040] Oral liquid compositions according to some embodiments of the present invention include branched-chain amino acids (BCAAs). It may be included. BCAAs include one or more of valine, leucine, and isoleucine. This is sufficient. The BCAA content is preferably 300-900 mg / 100 mL, and more preferably The appropriate concentration is 350-800 mg / 100 mL, and more preferably 400-700 mg The amount is 500-600 mg / 100 mL, more preferably 500-600 mg / 100 mL. In this context, the BCAA content refers to the total amount of valine, leucine, and isoleucine. The content of any of these amino acids may be zero. The inclusion of BCAAs helps to prevent fatigue. It is preferable in that it can be expected to be effective against infection. The amount of BCAA in the oral liquid composition is high-performance liquid crystal It can be determined by measuring with chromatography (HPLC), but the content can be calculated from the amount added. If possible, it can be determined from the amount of ingredients used. Measurement is performed using high-performance liquid chromatography (HPLC). The measurement conditions in this case can be measured using the analyzer's standard measurement method. High-performance liquid chromatography When measuring with Raffy (HPLC), a reversed-phase HPLC column (for example, RP-18 (dimensions: 25 × A particle size of 0.46 cm and 5 μm can be used.

[0041] Oral liquid compositions according to some embodiments of the present invention may contain sodium. The sodium contained in oral liquid compositions may be derived from raw materials such as collagen. It may also be added separately in the form of sodium citrate, etc. The amount is preferably 50-200 mg / 100 mL, more preferably 70-180 mg mg / 100mL, more preferably 100-160 mg / 100mL, even more preferably The amount is approximately 135-155 mg / 100 mL. The presence of sodium contributes to a full-bodied feel. It is preferable in that it improves the mouthfeel. The amount of sodium in the oral liquid composition is atomic It can be measured by absorbance spectroscopy. Note that the sodium content in the oral liquid composition is also measured. If the amount of compound used is known, the value calculated from that amount may be used.

[0042] Sodium is included in oral liquid compositions in an ingestible form, and its form is not particularly limited. Although it is not something that is done, for example, sodium chloride, sodium hydroxide, sodium malate Sodium sulfate, sodium citrate (monosodium citrate, disodium citrate) (Sodium citrate or trisodium citrate), sodium phosphate, sodium carbonate, sodium disulfide Sodium bicarbonate, sodium alginate, sodium alginate, glucohepta Sodium tartrate, sodium gluconate, sodium glutamate, sodium tartrate, Sodium aspartate, sodium lactate, sodium caseinate, sodium ascorbate at least one form selected from the group consisting of lium and mixtures thereof, or a It may also be in the form of an onide.

[0043] The pH of the oral liquid composition according to some embodiments of the present invention is preferably 4 to 7, or 4. 5-7, 5-7, 5.5-7, 6-7, 4-6.8, 4.5-6.8, 5-6.8, 5. 5-6.8, 6-6.8, 4-6.6, 4.5-6.6, 5-6.6, 5.5-6.6 Alternatively, a pH of 6-6.6 is also acceptable. By adjusting the pH within this range, a less acidic taste can be achieved. It can achieve a great taste.

[0044] The Brix (soluble solids content) of oral liquid compositions according to some embodiments of the present invention is preferably More preferably 5 to 20, more preferably 8 to 16, and even more preferably 10 to 14. Yes, the Brix (soluble solids content) of an oral liquid composition can be measured using a sugar refractometer. .

[0045] Oral liquid compositions according to some embodiments of the present invention may contain sweeteners. As a flavoring, it may contain low-intensity sweeteners, high-intensity sweeteners, or a combination thereof. Examples of low-sweetness sweeteners include glucose, sucrose (such as granulated sugar), Fructose, maltose, oligosaccharides, high-fructose corn syrup, lactose, psicose, allose Examples include tagatose, xylose, or ribose. Examples of high-intensity sweeteners include Aspartame, neotame, advantame, sucralose, acesulfame potassium Acesulfame K, saccharin, sodium saccharin, sodium cyclamate Um, dulcin, disodium glycyrrhizinate, trisodium glycyrrhizinate, Neo Hesperidin dihydrochalcone, thaumatin, monellin, curculin, mavinrin, bra Zein, Pentazol, Hernandultin, 4β-Hydroxyhernandultin, Miraculin Glycyrrhizin, rubusoside, phyllodulcin, mogroside IV, mogroside V, ste Biol glycosides (rebaudioside A, rebaudioside D, rebaudioside M), thaumatis Examples include monellin, blazein, monatin, monacillus fruit extract, or stevia extract. .

[0046] Oral liquid compositions according to some embodiments of the present invention, as long as the effects of the present invention are not impaired In addition to the above-mentioned components, the composition may also contain other components that can be added to a typical oral liquid composition. Such ingredients include, for example, acidulants, flavorings, vitamins, colorants, antioxidants, and milk. Examples include chemical additives, preservatives, seasonings, extracts, pH adjusters, and quality stabilizers.

[0047] The form of the container for the oral liquid composition according to some embodiments of the present invention is not limited to, for example, The product is sealed in containers such as cans, bottles, PET bottles, pouches, paper cartons, and plastic containers. It may also be in the form of an oral liquid composition packaged in a container. According to a preferred embodiment of the present invention, The container for the oral liquid composition is a small, individually packaged pouch for easy and regular consumption. When heat sterilization is performed after cooking, there are no particular limitations on the type of sterilization, such as inversion sterilization or UHT sterilization. This can be done using conventional methods such as bacterial and retort sterilization. The temperature of the heat sterilization process is While not particularly limited, for example, 65-130°C, preferably 80-120°C, for 1-40 minutes. However, if a sterilization effect equivalent to the above conditions can be obtained, it can be done at an appropriate temperature for a few seconds, for example, 5 to Sterilization in 30 seconds is also acceptable.

[0048] When taking an oral liquid composition according to some embodiments of the present invention, the daily intake is The recommended dosages are 100ml / day, 80ml / day, 68ml / day, 50ml / day, and 42ml / It may be 20 ml / day or 20 ml / day. Alternatively, it may be packaged in small bottles or small pouches. In that case, you may take one bottle or one pouch per day.

[0049] [Embodimentary Embodiments of the Oral Liquid Composition of the Present Invention] The following are exemplary embodiments of the oral liquid composition of the present invention, but the present invention is an embodiment described below. It is not limited to that. According to one embodiment of the present invention, an oral liquid composition, Collagen that is 6g / 100ml or more and less than 20g / 100ml Anserine and calcium carbonate in amounts exceeding 0.25g / 100ml and less than 2.0g / 100ml One selected from the group consisting of nosine, balenine, homoanserine, and homocarnosine. The above imidazole dipeptides and Includes, The total content of anserine and carnosine is 0.3 to 1.6 g / 100 ml, preferably 0 0.35~1.4g / 100ml, more preferably 0.5~1.3g / 100ml, and further Preferably 0.6 to 1.0 g / 100 ml, more preferably 0.6 to 0.9 g / 1 A composition is provided in 00 ml.

[0050] According to one embodiment of the present invention, an oral liquid composition, 6-13g / 100ml or 6.1-13g / 100ml of collagen and Anserine and calcium carbonate in amounts exceeding 0.25g / 100ml and less than 2.0g / 100ml One selected from the group consisting of nosine, balenine, homoanserine, and homocarnosine. The above imidazole dipeptides and Includes, The total content of anserine and carnosine is 0.3 to 1.6 g / 100 ml, preferably 0 0.35~1.4g / 100ml, more preferably 0.5~1.3g / 100ml, and further Preferably 0.6 to 1.0 g / 100 ml, more preferably 0.6 to 0.9 g / 1 A composition is provided in 00 ml.

[0051] According to one embodiment of the present invention, an oral liquid composition, 6-11g / 100ml or 6.1-11g / 100ml of collagen and Anserine and calcium carbonate in amounts exceeding 0.25g / 100ml and less than 2.0g / 100ml One selected from the group consisting of nosine, balenine, homoanserine, and homocarnosine. The above imidazole dipeptides and Includes, The total content of anserine and carnosine is 0.3 to 1.6 g / 100 ml, preferably 0 0.35~1.4g / 100ml, more preferably 0.5~1.3g / 100ml, and further Preferably 0.6 to 1.0 g / 100 ml, more preferably 0.6 to 0.9 g / 1 A composition is provided in 00 ml.

[0052] According to one embodiment of the present invention, an oral liquid composition, 6-11g / 100ml or 6.1-11g / 100ml of collagen and 0.3-1.5g / 100ml of anserine, carnosine, balenine, and homoanserine and one or more imidazole dipeptides selected from the group consisting of homocarnosine and Includes, The total content of anserine and carnosine is preferably 0.35 to 1.4 g / 100 ml. 0.5-1.3g / 100ml, more preferably 0.6-1.0g / 100ml, further A composition is provided, preferably containing 0.6 to 0.9 g / 100 ml.

[0053] According to one embodiment of the present invention, an oral liquid composition, 6-11g / 100ml or 6.1-11g / 100ml of collagen and 0.3-1.5g / 100ml of anserine, carnosine, balenine, and homoanserine and one or more imidazole dipeptides selected from the group consisting of homocarnosine and Includes, The total content of anserine and carnosine is preferably 0.35 to 1.4 g / 100 ml. 0.5-1.3g / 100ml, more preferably 0.6-1.0g / 100ml, further Preferably, it is 0.6 to 0.9 g / 100 ml. A composition containing 70-180 mg / 100 mL of sodium is provided.

[0054] 2. Method for producing oral liquid compositions In one embodiment, the present invention provides a method for producing an oral liquid composition as described below (hereinafter referred to as "the production method of the present invention"). The present invention provides a manufacturing method (also called the "method"). The present invention provides collagen, anserine, and carnosine. One or more selected from the group consisting of , balenine, homoanserine, and homocarnosine. The content of the imidazole dipeptide is within a predetermined range, as long as an oral liquid composition is obtained. It will not be done.

[0055] One example of a manufacturing method in one embodiment of the present invention is as follows: First, chicken These are finely chopped, and then treated in a solvent at high temperature under normal or pressurized conditions to extract the contents from chicken meat, etc. It breaks down proteins and other substances and converts them into relatively low molecular weight peptides that are easily absorbed by humans. The crude extract obtained is then used to remove fats and cholesterol, and then excess solvents are removed. This increases the concentration of the chicken essence. This operation can be repeated multiple times. After confirming that the nutritional value falls within the desired range, the product is filtered, then bottled and vacuum-packed. Then, it is heat-sterilized. The ratio of components varies depending on the part of the chicken used. Therefore, by preparing the parts of the chicken meat used, the desired amount of collagen and imidazole can be obtained. A dipeptide-rich oral liquid composition can be obtained. For example, collagen can be obtained from chicken leg portion. It tends to be found in large quantities in chicken, and imidazole dipeptide is found in large quantities in chicken breast meat. There is a tendency for this to happen. Therefore, we analyze the amount of components contained in each part and the ratio of parts to use. By appropriately adjusting the ratio, the oral liquid composition of the present invention can be manufactured without excessive burden. ru.

[0056] Alternatively, by adding a predetermined amount of collagen and imidazole dipeptide to water, the following steps are performed: A clear oral liquid composition may be prepared. In this case, collagen and imidazole dipeptide may be used. The chicken extract contains collagen and / or imidazole dipeptides as needed. By adding it, the amount of collagen and imidazole dipeptide contained in the oral liquid composition You may adjust the amount. Chicken extract may be prepared using chicken meat, etc., in the manner described above. Commercially available products can also be used. Note that the timing of adding each ingredient can be simultaneous or not. That's good too.

[0057] In a manufacturing method according to one embodiment of the present invention, "oral liquid composition", "collagen", "imida Regarding "zole dipeptide," "chicken extract," and "other ingredients and properties," see above. The definition is the same as that stated in the section on oral liquid compositions, and the numerical value is the same as that in the section on oral beverage compositions mentioned above. The numbers mentioned above apply directly.

[0058] 3. Method for improving the taste quality of collagen-containing oral liquid compositions In one aspect, the present invention provides a method for improving the taste quality of the following collagen-containing oral liquid composition (hereinafter) The present invention provides an improved method (also known as "the improved method of the present invention"). According to the improved method of the present invention, collagen This can reduce the collagen-specific odor (fishy smell) present in the oral liquid composition containing it. Specifically, an orally liquid composition containing collagen, anserine, carnosine, valer One or more imida selected from the group consisting of nin, homoanserine, and homocarnosine. By adjusting the concentration of zole dipeptides, the characteristic odor of collagen can be eliminated. It can reduce the (fishy smell).

[0059] An improvement method according to one embodiment of the present invention is a method for improving the taste quality of a collagen-containing oral liquid composition. The amount of collagen contained in the collagen-containing oral liquid composition is 6 g / 100 ml. It is 1 or more, and 0 per 1g of collagen contained in the collagen-containing oral liquid composition. 0.04-0.5g of anserine, carnosine, balenine, homoanserine and homocar Prepare to contain one or more imidazole dipeptides selected from the group consisting of nosine. That is the method.

[0060] In improved methods according to several embodiments of the present invention, collagen-containing oral liquid composition The collagen contained in 1g contains anserine, carnosine, balenine, and homoanserine. The content of one or more imidazole dipeptides selected from the group consisting of homocarnosine and homocarnosine. The available amounts are 0.04-0.4g, 0.04-0.3g, 0.04-0.25g, and 0.04- 0.2g, 0.04~0.15g, 0.04~0.1g, 0.05~0.4g, 0.05 ~0.3g, 0.05~0.25g, 0.05~0.2g, 0.05~0.15g, 0. 05~0.1g, 0.06~0.4g, 0.06~0.3g, 0.06~0.25g, 0 .06~0.2g, 0.06~0.15g, 0.06~0.1g, 0.07~0.4g, 0.07~0.3g, 0.07~0.25g, 0.07~0.2g, 0.07~0.15 g, 0.07~0.1g, 0.08~0.4g, 0.08~0.3g, 0.08~0.2 Even if it is 5g, 0.08-0.2g, 0.08-0.15g, or 0.08-0.1g good.

[0061] In improved methods according to several embodiments of the present invention, collagen-containing oral liquid composition The total amount of anserine and carnosine per gram of collagen contained in is 0.0 4~0.4g, 0.04~0.3g, 0.04~0.25g, 0.04~0.2g, 0. 04~0.15g, 0.04~0.1g, 0.05~0.4g, 0.05~0.3g, 0 .05~0.25g, 0.05~0.2g, 0.05~0.15g, 0.05~0.1g , 0.06~0.4g, 0.06~0.3g, 0.06~0.25g, 0.06~0.2 g, 0.06~0.15g, 0.06~0.1g, 0.07~0.4g, 0.07~0. 3g, 0.07~0.25g, 0.07~0.2g, 0.07~0.15g, 0.07~ 0.1g, 0.08~0.4g, 0.08~0.3g, 0.08~0.25g, 0.08 It may be ~0.2g, 0.08~0.15g, or 0.08~0.1g.

[0062] In this specification, "1g of collagen contained in a collagen-containing oral liquid composition" "Adjust to contain 0.04-0.5g of imidazole dipeptide" is what Collard said. The amount of imidazole dipeptide in the gen-containing liquid composition is ultimately As long as it is between 0.04 and 0.5g, it is not particularly limited. Therefore, collagen-containing oral supplements The liquid composition may also be prepared by separately adding collagen preparations or imidazole dipeptide preparations. Furthermore, by preparing the raw materials used in the production of collagen-containing oral liquid compositions, the final product contains collagen. The amounts of collagen and imidazole dipeptide may be adjusted.

[0063] In some embodiments of the present invention, collagen contained in an oral liquid composition containing collagen The amount of collagen is less than 20 g / 100 ml. In a preferred embodiment of the present invention, collagen The collagen content is 6-19g / 100ml, 6-18g / 100ml, and 6-17g / 100ml. 00ml, 6~16g / 100ml, 6~15g / 100ml, 6~14g / 100ml , 6~13g / 100ml, 6~12g / 100ml, 6~11g / 100ml, 6~1 0g / 100ml, 6g / 100ml or more, and less than 10g / 100ml, 6-9g / 100ml, 6-8g / 100ml, 6-7g / 100ml, over 6g / 100ml, and Less than 13g / 100ml, more than 6g / 100ml, and 12g / 100ml or less, 6g / 100ml or more, and 11g / 100ml or less, 6g / 100ml or more, and 10g / Less than 100ml, more than 6g / 100ml, and less than 10g / 100ml, 6g / 100ml Greater than 1 liter and 9g / 100ml or less, greater than 6g / 100ml and 8g / 100ml or less , more than 6g / 100ml and 7g / 100ml or less, 6.1g / 100ml or more, Less than 13g / 100ml, 6.1-12g / 100ml, 6.1-11g / 100ml , 6.1~10g / 100ml, 6.1g / 100ml or more, and 10g / 100ml Less than, 6.1~9g / 100ml, 6.1~8g / 100ml, 6.1~7g / 100m l, 6.2g / 100ml or more, and less than 13g / 100ml, 6.2~12g / 10 0ml, 6.2~11g / 100ml, 6.2~10g / 100ml, 6.2g / 100 ml or more, and less than 10g / 100ml, 6.2-9g / 100ml, 6.2-8g / 100ml, 6.2-7g / 100ml, 6.5g / 100ml or more, and 13g / 1 Less than 00ml, 6.5g~12g / 100ml, 6.5~11g / 100ml, 6.5~ 10g / 100ml, 6.5g / 100ml or more, and less than 10g / 100ml, 6. 5~9g / 100ml, 6.5~8g / 100ml, 6.5~7g / 100ml, 7g / 100ml or more, and less than 13g / 100ml, 7-12g / 100ml, 7-11g / 100ml, 7-10g / 100ml, 7g / 100ml or more, and 10g / 100 Less than ml, 7-9 g / 100 ml, 7-8 g / 100 ml, 8 g / 100 ml or more, and Less than 13g / 100ml, 8-12g / 100ml, 8-11g / 100ml, 8-1 0g / 100ml, 8g / 100ml or more, and less than 10g / 100ml or 8-9g It may be g / 100ml. The collagen content is more preferably 6-11g / 1 00ml, 6g / 100ml to 10g / 100ml or 6.1g / 100ml or more, Furthermore, it is less than 10g / 100ml.

[0064] In one embodiment of the present invention, an improved method involves "oral liquid composition," "collagen," and "imida." Regarding "zole dipeptide," "chicken extract," and "other ingredients and properties," see above. The definition is the same as that given in the section on oral liquid compositions.

[0065] In this specification, the phrase "at least" means that the number of specific items is greater than or equal to the number listed. It means that it may be so. Also, within this application, the word "about" means that the subject is "about". The value that follows is within the range of ±25%, ±10%, ±5%, ±3%, ±2%, or ±1%. It means that... For example, "approximately 10" means a range of 7.5 to 12.5. [Examples]

[0066] The present invention will be specifically described below with reference to examples, but the present invention is limited to the following examples. It's not that.

[0067] [Example 1] <Examples 1-1 to 1-39> An oral liquid composition was obtained by mixing the raw materials shown in Table 1 with water. The raw materials used were as follows: As is the case: Collagen preparation (manufactured by Rousselot, "Peptan F 2000 HD", pure collagen) Degree: 90% or more, fish-derived collagen peptide, imidazole dipeptide preparation (Lytone E Imida 15, manufactured by Interprise, contains anserine and carnosine with a purity of 15% or more. (10% or more of sulfame, 5% or more of carnosine) and water (RO water (reverse osmosis water)). [Table 1]

[0068] The collagen content and the total content of anserine and carnosine in each sample are as follows: A Certificate of Analysis (COA) shows the detailed content of each component in each batch of raw materials. This was calculated based on information from (e of Analysis).

[0069] The taste quality of the oral liquid compositions obtained using the above procedure was evaluated by three expert panelists. The names were evaluated based on the following criteria. [Table 2]

[0070] Before conducting the test, the panelists thoroughly discussed and agreed on the above evaluation criteria. The results are summarized in Table 3. The results shown in Table 3 are the average of the scores given by the three expert panelists. Furthermore, among the results obtained, the worse of the evaluation results for "bitterness" and "unpleasant fishy smell" was considered. The score was used as the overall evaluation. [Table 3]

[0071] [Example 2] <Examples 2-1 to 2-20> An oral liquid composition was obtained by mixing the raw materials shown in Table 4 with water. The raw materials used were as follows: As is the case: Collagen preparation (manufactured by Rousselot, "Peptan F 2000 HD", pure collagen) Degree: 90% or more, fish-derived collagen peptide, imidazole dipeptide preparation (Lytone E Imida 15, manufactured by Interprise, contains anserine and carnosine with a purity of 15% or more. (10% or more of citric acid, 5% or more of carnosine), water (RO water (reverse osmosis water)), and citric acid (3%) Sodium preparation (manufactured by Jungbunzlauer Canada Inc., "Trisodium citrate dehydrate fin") e F60000”, purity: 99% or more). [Table 4]

[0072] The collagen content and the total content of anserine and carnosine in each sample are as follows: A Certificate of Analysis (COA) shows the detailed content of each component in each batch of raw materials. The sodium content in each sample was calculated based on information from the analysis of the COLA The amount of sodium originally contained in the enzyme preparation and the imidazole dipeptide preparation is included in the analysis certificate. Based on the information provided, the sodium content was calculated from the amount of trisodium citrate added. The amount of sodium contained in the collagen preparation used in this example was calculated by adding the sodium content. The amount of um is 0.24% by weight, and the amount of sodium contained in the imidazole dipeptide preparation is 0 It was 0.95% by weight.

[0073] The taste quality of the oral liquid compositions obtained using the above procedure was evaluated by three expert panelists. The names were evaluated based on the following criteria. A score of 3 or higher is preferred for body feel (mouth feel). This is an evaluation. [Table 5]

[0074] Before conducting the test, the panelists thoroughly discussed and agreed on the above evaluation criteria. The results are summarized in Table 6. The results shown in Table 6 are the average of the scores given by the three expert panelists. . [Table 6]

Claims

1. An oral liquid composition, Collagen that is 6g / 100ml or more and less than 20g / 100ml Anserine and calcium carbonate in concentrations exceeding 0.25 g / 100 ml and less than 2.0 g / 100 ml. One selected from the group consisting of nosine, balenine, homoanserine, and homocarnosine. The above imidazole dipeptides and A composition containing the following:

2. The content of one or more of the aforementioned imidazole dipeptides is 0.3 to 1.6 g / 100 ml. The composition according to claim 1.

3. The content of one or more of the aforementioned imidazole dipeptides is 0.35 to 1.4 g / 100 ml. A composition according to claim 1.

4. The collagen content is 6 to 11 g / 100 ml. The content of one or more of the aforementioned imidazole dipeptides is 0.5 to 1.3 g / 100 ml. The composition according to claim 1.

5. The collagen content is 6 to 10 g / 100 ml. The content of one or more of the aforementioned imidazole dipeptides is 0.6 to 1.25 g / 100 ml. A composition according to claim 1.

6. Let Y be the collagen content (g / 100ml), and let carnosine and anserine be... When the total content is X (g / 100ml), equation (1) is: Y≧-17.705X+16.705 (1) A composition according to any one of claims 3 to 5, which satisfies the requirements.

7. A composition according to any one of claims 1 to 6, comprising anserine and carnosine.

8. A substance comprising 50 to 200 mg / 100 mL of sodium, as described in any one of claims 1 to 7. The composition of the listed items.

9. A compound comprising 300 to 900 mg / 100 mL of BCAA, as described in any one of claims 1 to 8. The composition of the listed items.

10. The composition according to any one of claims 1 to 9, which is a soup in a pouch.

11. A method for improving the taste quality of a collagen-containing oral liquid composition, wherein the collagen-containing oral liquid The composition contains 6 g / 100 ml or more of collagen, and the collagen-containing oral The liquid composition contains 0.04 to 0.5 g of anserine and carnosine per 1 g of collagen. One selected from the group consisting of syn, balenine, homoanserine, and homocarnosine A method for preparing the above imidazole dipeptide.

12. The amount of collagen contained in the aforementioned collagen-containing oral liquid composition is less than 20 g / 100 ml. The method according to claim 11.

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