Puncture catheter

Abstract

To provide a puncture catheter that makes it easier to reduce the amount of fluid used. [Solution] A puncture catheter 100 comprising: a medical puncture needle 1 having a longitudinal direction x and a lumen 1e extending in the longitudinal direction x; a cylindrical member 1020e connected to the puncture needle 1, having a lumen 1020e extending in the longitudinal direction x of the puncture needle 1 through which liquid passes; and an elongated member 60 disposed in the lumen 1020e of the cylindrical member 1020, having a length of 50 cm or more in the longitudinal direction x of the puncture needle 1, wherein the elongated member 60 has a contact portion 61 that abuts against the inner surface 1020c of the cylindrical member 1020, and is slidable in the longitudinal direction x of the puncture needle 1 within the lumen 1020e of the cylindrical member 1020.

Description

Technical Field

[0001] The present invention relates to a puncture catheter.

Background Art

[0002] For myocardial tissue having cardiomyocytes that are losing function due to myocardial infarction or the like, treatment such as regenerating cardiomyocytes is performed by directly administering a chemical solution such as a cardiomyocyte regeneration cell-containing solution. Thus, when directly administering a chemical solution to an organ in the body, it is necessary to insert a catheter having a needle into the body cavity and puncture the organ with the needle. As a catheter having a needle used in such treatment, for example, the following have been developed.

[0003] Patent Document 1 describes a catheter provided with a fixed piercing element having a spiral structure. This catheter is operated such that the spiral structure of the piercing element is screwed into the heart wall.

Prior Art Documents

Patent Documents

[0004]

Patent Document 1

Summary of the Invention

Problems to be Solved by the Invention

[0005] However, in the catheter described in Patent Document 1, there is a problem that the amount of liquid remaining in the catheter is large, and as a result, the amount of liquid used increases.

[0006] The present invention has been made in view of the above circumstances, and an object thereof is to provide a puncture catheter that can easily reduce the amount of liquid used.

Means for Solving the Problems

[0007] The puncture catheter according to an embodiment of the present invention that solves the above problems is as follows. [1] A medical puncture needle having a longitudinal direction and a lumen extending in the longitudinal direction, A cylindrical member having a lumen extending in the longitudinal direction through which liquid passes, and connected to the puncture needle, An elongated member is placed inside the cavity of the cylindrical member and has a length of 50 cm or more in the longitudinal direction, It has, The elongated member has a contact portion that abuts against the inner surface of the cylindrical member, and is slidable in the longitudinal direction within the lumen of the cylindrical member, forming a puncture catheter.

[0008] By positioning the elongated member inside the lumen of the cylindrical member, the liquid present in the lumen of the cylindrical member can be pushed distally. This reduces the amount of liquid remaining in the lumen of the cylindrical member, making it easier to reduce the amount of liquid used.

[0009] The puncture catheter according to the embodiment of the present invention is preferably one of the following [2] to [9]. [2] The puncture catheter according to [1], wherein the tubular member has a metal layer. [3] The puncture catheter according to [2], wherein the cylindrical member has an outer resin layer located radially outward of the cylindrical member than the metal layer. [4] The puncture catheter according to [2] or [3], wherein the cylindrical member has an inner resin layer located radially inward of the cylindrical member than the metal layer. [5] The cylindrical member is The first cylindrical member having a lumen extending in the longitudinal direction, A second cylindrical member is disposed within the lumen of the first cylindrical member and has a lumen extending in the longitudinal direction through which liquid passes; It has, The puncture catheter described in [1], wherein the elongated member is positioned in the lumen of the second cylindrical member. [6] The distal end of the elongated member is insertable into the lumen of the puncture needle. The puncture catheter according to any one of [1] to [5]. [7] The distal end of the elongated member is made to contact the proximal end of the puncture needle, as described in any one of [1] to [5]. [8] The puncture catheter according to any one of the items [1] to [7], wherein the proximal end of the elongated member is located more proximal to the proximal end of the tubular member. [9] The puncture catheter according to any one of [1] to [8], wherein the elongated member has a section proximal to the contact portion in which the radial length of the cylindrical member is shorter than that of the contact portion. [Effects of the Invention]

[0010] By positioning the elongated member inside the lumen of the cylindrical member, the liquid present in the lumen of the cylindrical member can be pushed distally. This reduces the amount of liquid remaining in the lumen of the cylindrical member, making it easier to reduce the amount of liquid used. [Brief explanation of the drawing]

[0011] [Figure 1] Figure 1 shows a side view of a puncture catheter according to an embodiment of the present invention. [Figure 2] Figure 2 shows a cross-sectional view of the puncture catheter shown in Figure 1. [Figure 3] Figure 3 shows a cross-sectional view of the puncture catheter shown in Figure 2 along line III-III. [Figure 4] Figure 4 shows a side view of a puncture catheter according to an embodiment of the present invention. [Figure 5] Figure 5 shows a cross-sectional view of the puncture catheter shown in Figure 4. [Figure 6] Figure 6 shows a cross-sectional view of the puncture catheter shown in Figure 5 along the VI-VI line. [Modes for carrying out the invention]

[0012] One embodiment of the puncture catheter of the present invention includes a medical puncture needle having a longitudinal direction and a lumen extending in the longitudinal direction, a lumen extending in the longitudinal direction of the puncture needle and through which a liquid passes, and a cylindrical member connected to the puncture needle. The long member is disposed in the lumen of the cylindrical member and has a length of 50 cm or more in the longitudinal direction of the puncture needle. The long member has a contact portion that contacts the inner surface of the cylindrical member and is slidable in the longitudinal direction of the puncture needle within the lumen of the cylindrical member.

[0013] Hereinafter, the present invention will be specifically described with reference to the drawings. However, the present invention is not limited to the illustrated examples, and it is also possible to appropriately modify and implement it within the range that can conform to the gist of the foregoing and following descriptions, and all of them are included in the technical scope of the present invention. In each figure, for convenience, hatching, reference signs, etc. may be omitted, but in such cases, reference shall be made to the specification and other figures. Also, the dimensions of various components in the drawings may differ from the actual dimensions because priority is given to facilitating understanding of the features of the present invention.

[0014] Referring to FIGS. 1 to 6, the overall configuration of the puncture catheter according to an embodiment of the present invention will be described. FIGS. 1 and 4 show side views of the puncture catheter according to an embodiment of the present invention. FIG. 2 shows a cross-sectional view of the puncture catheter shown in FIG. 1. More specifically, it shows a cross-section passing through the central axis of the cylindrical member and parallel to the longitudinal direction of the cylindrical member. FIG. 3 shows a cross-sectional view taken along line III-III of the puncture catheter shown in FIG. 2. FIG. 5 shows a cross-sectional view of the puncture catheter shown in FIG. 4. More specifically, it shows a cross-section passing through the central axis of the cylindrical member and parallel to the longitudinal direction of the cylindrical member. FIG. 6 shows a cross-sectional view taken along line VI-VI of the puncture catheter shown in FIG. 5. FIGS. 1 to 6 show a puncture catheter 100 having a puncture needle 1 and a cylindrical member 1020.

[0015] In this drawing, the longitudinal direction of the puncture needle 1 is indicated by x, the radial direction of the puncture needle 1 is indicated by y, and the circumferential direction of the puncture needle 1 is indicated by c. The radial direction y is a direction perpendicular to the longitudinal direction x. The longitudinal direction x of the puncture needle 1 can also be said to be the extending direction of the puncture needle 1. For ease of understanding, in this drawing, the longitudinal direction x of the puncture needle 1 coincides with the longitudinal direction of the cylindrical member 1020, the radial direction y of the puncture needle 1 coincides with the radial direction of the cylindrical member 1020, and the circumferential direction c of the puncture needle 1 coincides with the circumferential direction of the cylindrical member 1020, but the present invention is not limited to this aspect.

[0016] In this specification, the proximal side refers to the direction on the user's hand side with respect to the longitudinal direction x of the puncture needle 1, and the distal side refers to the opposite side of the proximal side, that is, the direction on the treatment target side. Also, when each member is bisected in the longitudinal direction x of the puncture needle 1, the portion located on the distal side of each member is referred to as the distal portion, and the portion located on the proximal side of each member is referred to as the proximal portion. The distal end of each member is the end located on the most distal side of each member. The proximal end of each member is the end located on the most proximal side of each member. The end of each member refers to the portion including the end of each member and its periphery. That is, the distal end portion of each member refers to the portion including the distal end of each member and its periphery, and the proximal end portion of each member refers to the portion including the proximal end of each member and its periphery.

[0017] The puncture catheter 100 has a puncture needle 1, a cylindrical member 1020, and a long member 60.

[0018] The puncture needle 1 is for medical use and is to be punctured into the target tissue. As shown in FIGS. 1, 2, 4, and 5, the puncture needle 1 has a longitudinal direction x and has a lumen 1e extending in the longitudinal direction x. Through this lumen 1e, liquids such as cell-containing fluid and drug solution can be transported to the target tissue.

[0019] As shown in FIGS. 1 to 6, the cylindrical member 1020 is a cylindrical member. The cylindrical member 1020 is connected to the puncture needle 1 and has a lumen 1020e extending in the longitudinal direction x of the puncture needle 1. Liquids such as cell-containing fluid and drug solution pass through this lumen 1020e.

[0020] As shown in Figures 1 to 6, the elongated member 60 is an elongated member that is positioned in the lumen 1020e of the cylindrical member 1020. The length of the elongated member 60 in the longitudinal direction x of the puncture needle 1 is 50 cm or more.

[0021] As shown in Figures 2 and 5, the elongated member 60 has a contact portion 61 that abuts against the inner surface 1020c of the cylindrical member 1020. The elongated member 60 is slidable in the longitudinal direction x of the puncture needle 1 within the lumen 1020e of the cylindrical member 1020.

[0022] By positioning the elongated member 60 in the lumen 1020e of the cylindrical member 1020, the liquid present in the lumen 1020e of the cylindrical member 1020 can be pushed distally. This reduces the amount of liquid remaining in the lumen 1020e of the cylindrical member 1020, making it easier to reduce the amount of liquid used.

[0023] The puncture catheter 100 is used to administer liquids such as cell-containing solutions or drug solutions to target tissues. Specifically, the puncture catheter 100 is preferably used for direct administration to internal organs, such as the heart, kidneys, and liver. The liquid administered using the puncture catheter 100 is preferably a cell-containing solution. For example, the puncture catheter 100 can be used to directly administer iPS cell-containing solutions to the liver or kidneys, or to directly administer myocardial regeneration cell-containing solutions to the heart, or more specifically, the myocardium.

[0024] The puncture needle 1 is preferably designed to puncture internal organs. Internal organs refer to organs located inside the body, particularly in the abdomen and chest, and are also known as viscera.

[0025] The puncture needle 1 can be made of, for example, metal or resin. The puncture needle 1 may be made entirely of metal, or entirely of resin. The puncture needle 1 may be made partly of metal and the other part of resin.

[0026] The puncture needle 1 is preferably made of metal only. Examples of metals that make up the puncture needle 1 include stainless steel such as SUS304 and SUS316, platinum, nickel, cobalt, chromium, titanium, tungsten, gold, Ni-Ti alloy, Co-Cr alloy, or combinations thereof.

[0027] Examples of resins that make up the puncture needle 1 include polyether ether ketone (PEEK) and polycarbonate (PC). By constructing the puncture needle 1 using only resin and no metal, the puncture needle 1 can be used even in patients with metal allergies.

[0028] The puncture needle 1 may have a distal end 1a and a proximal end 1b. The puncture needle 1 may have an inner surface 1c facing the lumen 1e of the puncture needle 1 and an outer surface 1d facing the outside of the puncture needle 1.

[0029] The length of the puncture needle 1 in the longitudinal direction x can be 2 mm or more, 3 mm or more, 4 mm or more, etc. The length of the puncture needle 1 in the longitudinal direction x can be 50 mm or less, 30 mm or less, 10 mm or less, etc. The length of the puncture needle 1 in the longitudinal direction x refers to the longest length of the puncture needle 1 in the longitudinal direction x. When used as a puncture catheter for puncturing the myocardium, the length of the puncture needle 1 in the longitudinal direction x is preferably 5 mm.

[0030] The length of the puncture needle 1 in the radial direction y can be 0.2 mm or more, 0.3 mm or more, 0.4 mm or more, etc. The length of the puncture needle 1 in the radial direction y can be 10 mm or less, 5 mm or less, 1 mm or less, etc. The length of the puncture needle 1 in the radial direction y refers to the longest length of the puncture needle 1 in the radial direction y. When used as a puncture catheter for puncturing the myocardium, the length of the puncture needle 1 in the radial direction y is preferably 0.45 mm.

[0031] As shown in Figures 4 and 5, the puncture needle 1 may have a cylindrical member 2 and a spiral member 3.

[0032] The tubular member 2 is a tubular member and may have a lumen 2e extending in the longitudinal direction x of the puncture needle 1. This lumen 2e corresponds to the lumen 1e of the puncture needle 1. Through this lumen 2e, liquids such as cell-containing fluid or drug solutions can be delivered to the target tissue. The tubular member 2 may have a distal end 2a and a proximal end 2b.

[0033] The helical member 3 is preferably a member in which a wire 4 is wound in a helical shape. The wire 4 is preferably wound around the cylindrical member 2.

[0034] Regarding the puncture needle 1, by adopting a design in which a spiral member 3 is arranged around a cylindrical member 2, it becomes easier to screw the puncture needle 1 into the target tissue by rotating the puncture needle 1 around the cylindrical member 2 as an axis. This makes it easier to puncture the target tissue with the puncture needle 1. In addition, the wire 4 that makes up the spiral member 3 bites into the tissue, making it difficult for the puncture needle 1 to come out of the tissue. Furthermore, the puncture depth can be easily adjusted by adjusting the rotation of the puncture needle 1.

[0035] It is preferable that a hole 5 is formed in the puncture needle 1, connecting the lumen 1e of the puncture needle 1 to the outside of the puncture needle 1. Liquids such as cell-containing fluid or drug solution that have been transported through the lumen 1e are delivered to the target tissue through this hole 5.

[0036] The puncture needle 1 may have only one hole 5 or multiple holes 5. If only one hole 5 is formed on the puncture needle 1, it becomes easier to administer liquids such as cell-containing fluid or drug solutions to a specific point. If multiple holes 5 are formed on the puncture needle 1, it becomes easier to administer liquids such as cell-containing fluid or drug solutions to a wider area.

[0037] When observed from a direction perpendicular to the longitudinal direction x of the puncture needle 1, the outer shape of the hole 5 can be a polygon such as a triangle, square, or pentagon, or a circle, an ellipse, or a combination thereof. Polygons include not only those with clearly defined corner vertices and straight sides, but also rounded polygons with rounded corners, and those with at least some of their sides being curved.

[0038] The cylindrical member 1020 may have a distal end 1020a and a proximal end 1020b. It is preferable that the cylindrical member 1020 is connected to the proximal end of the puncture needle 1. It is more preferable that the distal end of the cylindrical member 1020 is connected to the proximal end of the puncture needle 1.

[0039] Preferably, the cylindrical member 1020 has an inner surface 1020c facing the inner lumen 1020e of the cylindrical member 1020 and an outer surface 1020d facing the outside of the cylindrical member 1020.

[0040] The method of connecting the cylindrical member 1020 and the puncture needle 1 is not particularly limited. Examples include fixing by welding, welding, bonding, crimping, etc.

[0041] The cylindrical member 1020 may consist of only one cylindrical member, or it may consist of multiple cylindrical members.

[0042] The cylindrical member 1020 can be made of resin, metal, or the like. The cylindrical member 1020 may be made entirely of metal, or entirely of resin. The cylindrical member 1020 may be made partly of metal and the other part of resin.

[0043] Examples of metals that make up the cylindrical member 1020 include stainless steel such as SUS304 and SUS316, platinum, nickel, cobalt, chromium, titanium, tungsten, gold, Ni-Ti alloy, Co-Cr alloy, or combinations thereof.

[0044] Examples of resins that make up the cylindrical member 1020 include synthetic resins such as polyolefin resins (e.g., polyethylene and polypropylene), polyamide resins (e.g., nylon), polyester resins (e.g., PET), aromatic polyetherketone resins (e.g., PEEK), polyetherpolyamide resins, polyurethane resins, polyimide resins, and fluororesins (e.g., PTFE, PFA, ETFE), or combinations thereof.

[0045] It is preferable that the cylindrical member 1020 includes a portion made of a material containing metal. Only a portion of the cylindrical member 1020 may be made of metal, or the entire cylindrical member 1020 may be made of metal.

[0046] As shown in Figures 2, 3, 5, and 6, it is preferable that the cylindrical member 1020 has a metal layer 11. Having a metal layer 11 in the cylindrical member 1020 makes it easier to create a puncture catheter 100 with high torque transmission capabilities.

[0047] Preferably, the metal layer 11 has an inner surface 11c located on the radially inward side of the cylindrical member 1020 and an outer surface 11d located on the radially outward side of the cylindrical member 1020.

[0048] The metal layer 11 may consist of a pipe, a coil around which wire is wound, a braid in which wire is woven, a pipe with holes or grooves formed therein, or a combination thereof.

[0049] It is preferable that the metal layer 11 has multiple grooves 11f formed therein. The grooves 11f may be closed grooves or through grooves. Both through grooves and closed grooves may be formed in the metal layer 11. By combining through grooves and closed grooves, or by selecting one or the other, it becomes easier to create a metal layer 11 with the desired flexibility and rigidity.

[0050] As shown in Figures 2 and 3, it is preferable that the cylindrical member 1020 has an outer resin layer 12 located radially outward from the metal layer 11. This makes it less likely for the metal layer 11 to get caught on the body cavity wall, even if holes or grooves 11f are formed in the metal layer 11, and makes it easier to ensure insertion within the body cavity.

[0051] The outer resin layer 12 may be positioned to cover only a portion of the outer surface 11d of the metal layer 11. Alternatively, the outer resin layer 12 may be positioned to cover the entire outer surface 11d of the metal layer 11.

[0052] As shown in Figures 5 and 6, the cylindrical member 1020 may have an inner resin layer 13 located radially inward of the cylindrical member 1020 compared to the metal layer 11.

[0053] The inner resin layer 13 may be positioned to cover only a portion of the inner surface 11c of the metal layer 11. Alternatively, the inner resin layer 13 may be positioned to cover the entire inner surface 11c of the metal layer 11.

[0054] Although not shown in the figures, the cylindrical member 1020 may have both an outer resin layer 12 placed on the outer surface 11d of the metal layer 11 and an inner resin layer 13 placed on the inner surface 11c of the metal layer 11.

[0055] The length of the tubular member 1020 in the longitudinal direction x of the puncture needle 1 can be 1100 mm or more, 1330 mm or more, 1560 mm or more, etc. The length of the tubular member 1020 in the longitudinal direction x of the puncture needle 1 can be 2300 mm or less, 2070 mm or less, 1840 mm or less, etc. The length of the tubular member 1020 in the longitudinal direction x of the puncture needle 1 refers to the longest length of the tubular member 1020 in the longitudinal direction x of the puncture needle 1. When used as a puncture catheter for puncturing the myocardium, the length of the tubular member 1020 in the longitudinal direction x of the puncture needle 1 is preferably 1500 mm.

[0056] The length of the cylindrical member 1020 in the radial direction y of the puncture needle 1 can be 0.3 mm or more, 0.5 mm or more, 0.8 mm or more, etc. The length of the cylindrical member 1020 in the radial direction y of the puncture needle 1 can be 20 mm or less, 15 mm or less, 10 mm or less, etc. The length of the cylindrical member 1020 in the radial direction y of the puncture needle 1 refers to the longest length of the cylindrical member 1020 in the radial direction y of the puncture needle 1. When used as a puncture catheter for puncturing the myocardium, it is preferable that the length of the cylindrical member 1020 in the radial direction y of the puncture needle 1 be 0.9 mm.

[0057] As shown in Figures 2 and 3, the cylindrical member 1020 may include a first cylindrical member 10 having a lumen 10e extending in the longitudinal direction x of the puncture needle 1, and a second cylindrical member 20 positioned in the lumen 10e of the first cylindrical member 10 and having a lumen 20e extending in the longitudinal direction x of the puncture needle 1, through which liquid passes. In this case, it is preferable that the elongated member 60 is positioned in the lumen 20e of the second cylindrical member 20.

[0058] The first cylindrical member 10 may have a distal end 10a and a proximal end 10b. Preferably, the first cylindrical member 10 is connected to the proximal end of the puncture needle 1. More preferably, the distal end of the first cylindrical member 10 is connected to the proximal end of the puncture needle 1.

[0059] It is preferable that the lumen 1e of the puncture needle 1 and the lumen 10e of the first cylindrical member 10 are not in communication with each other.

[0060] Preferably, the first cylindrical member 10 has an inner surface 10c facing the inner lumen 10e of the first cylindrical member 10 and an outer surface 10d facing the outside of the first cylindrical member 10.

[0061] The method of connecting the first cylindrical member 10 and the puncture needle 1 is not particularly limited. Examples include fixing by welding, welding, bonding, crimping, etc. Among these, it is preferable that the first cylindrical member 10 and the puncture needle 1 are welded together.

[0062] The first cylindrical member 10 may consist of only one cylindrical member, or it may consist of multiple cylindrical members.

[0063] The first cylindrical member 10 can be made of resin, metal, or other materials listed as capable of constituting the cylindrical member 1020. The first cylindrical member 10 may be made entirely of metal, or entirely of resin. The first cylindrical member 10 may be made partly of metal and the other part of resin.

[0064] The first cylindrical member 10 preferably includes a portion made of a material containing metal. Only a portion of the first cylindrical member 10 may be made of metal, or the entire first cylindrical member 10 may be made of metal.

[0065] As shown in Figures 2 and 3, it is preferable that the first cylindrical member 10 has a metal layer 11 made of metal. Having a metal layer 11 in the first cylindrical member 10 makes it easier to create a puncture catheter 100 with high torque transmission capabilities.

[0066] As shown in Figures 2 and 3, it is preferable that the first cylindrical member 10 has an outer resin layer 12 disposed on the outer surface 11d of the metal layer 11. This makes it less likely for the first cylindrical member 10 to get caught on the body cavity wall, even if holes or grooves 11f are formed in the metal layer 11, and makes it easier to ensure insertion within the body cavity.

[0067] Although not shown in the figures, the first cylindrical member 10 may have an inner resin layer disposed on the inner surface 11c of the metal layer 11.

[0068] Although not shown in the figures, the first cylindrical member 10 may have both an outer resin layer 12 disposed on the outer surface 11d of the metal layer 11 and an inner resin layer disposed on the inner surface 11c of the metal layer 11.

[0069] The second cylindrical member 20 may have a distal end 20a and a proximal end 20b. Preferably, the second cylindrical member 20 is connected to the proximal end of the puncture needle 1. More preferably, the distal end of the second cylindrical member 20 is connected to the proximal end of the puncture needle 1.

[0070] It is preferable that the lumen 1e of the puncture needle 1 and the lumen 20e of the second cylindrical member 20 are in communication.

[0071] Preferably, the second cylindrical member 20 has an inner surface 20c facing the inner lumen 20e of the second cylindrical member 20 and an outer surface 20d facing the outside of the second cylindrical member 20.

[0072] The method of connecting the second cylindrical member 20 and the puncture needle 1 is not particularly limited. Examples include fixing by welding, welding, adhesive, crimping, etc. Among these, it is preferable that the second cylindrical member 20 and the puncture needle 1 are bonded together with an adhesive.

[0073] For example, polyurethane-based, epoxy-based, cyano-based, fluorine-based, and silicone-based adhesives can be used.

[0074] The second cylindrical member 20 may consist of only one cylindrical member, or it may consist of multiple cylindrical members.

[0075] The second cylindrical member 20 can be made of resin, metal, or other materials listed as being capable of constituting the cylindrical member 1020. The second cylindrical member 20 may be made entirely of metal, or entirely of resin. The second cylindrical member 20 may be made partly of metal and the other part of resin.

[0076] The second cylindrical member 20 preferably includes a portion made of a resin-containing material. Only a portion of the second cylindrical member 20 may be made of resin, or the entire second cylindrical member 20 may be made of resin. The second cylindrical member 20 is preferably made of an elastically deformable material.

[0077] Although not shown in the figures, the second cylindrical member 20 may have a tapered portion at its distal end, where the outer diameter increases towards the distal end.

[0078] The length of the first cylindrical member 10 in the longitudinal direction x of the puncture needle 1 and the length of the second cylindrical member 20 in the longitudinal direction x of the puncture needle 1 can be 1100 mm or more, 1330 mm or more, 1560 mm or more, etc. The length of the first cylindrical member 10 in the longitudinal direction x of the puncture needle 1 and the length of the second cylindrical member 20 in the longitudinal direction x of the puncture needle 1 can be 2300 mm or less, 2070 mm or less, 1840 mm or less, etc. The length of the first cylindrical member 10 in the longitudinal direction x of the puncture needle 1 refers to the longest length of the length of the first cylindrical member 10 in the longitudinal direction x of the puncture needle 1. The length of the second cylindrical member 20 in the longitudinal direction x of the puncture needle 1 refers to the longest length of the length of the second cylindrical member 20 in the longitudinal direction x of the puncture needle 1. Furthermore, when used as a puncture catheter for puncturing the myocardium, it is preferable that the length of the first cylindrical member 10 in the longitudinal direction x of the puncture needle 1 and the length of the second cylindrical member 20 in the longitudinal direction x of the puncture needle 1 are 1500 mm. The length of the first cylindrical member 10 in the longitudinal direction x of the puncture needle 1 and the length of the second cylindrical member 20 in the longitudinal direction x of the puncture needle 1 may be the same or different.

[0079] The length of the first tubular member 10 in the radial direction y of the puncture needle 1 can be 0.3 mm or more, 0.5 mm or more, 0.8 mm or more, etc. The length of the first tubular member 10 in the radial direction y of the puncture needle 1 can be 20.0 mm or less, 15.0 mm or less, 10.0 mm or less, etc. The length of the first tubular member 10 in the radial direction y of the puncture needle 1 refers to the longest length of the first tubular member 10 in the radial direction y of the puncture needle 1. When used as a puncture catheter for puncturing the myocardium, it is preferable that the length of the first tubular member 10 in the radial direction y of the puncture needle 1 be 0.9 mm.

[0080] The length of the second cylindrical member 20 in the radial direction y of the puncture needle 1 can be 0.1 mm or more, 0.2 mm or more, 0.3 mm or more, etc. The length of the second cylindrical member 20 in the radial direction y of the puncture needle 1 can be 15.0 mm or less, 10.0 mm or less, 5.0 mm or less, etc. The length of the second cylindrical member 20 in the radial direction y of the puncture needle 1 refers to the longest length of the second cylindrical member 20 in the radial direction y of the puncture needle 1. When used as a puncture catheter for puncturing the myocardium, it is preferable that the length of the second cylindrical member 20 in the radial direction y of the puncture needle 1 be 0.5 mm.

[0081] Although not shown in the figures, the second cylindrical member 20 may have a tapered portion in which the outer diameter increases towards the proximal end. The second cylindrical member 20 may have a tapered portion at its proximal end in which the outer diameter increases towards the proximal end.

[0082] The second cylindrical member 20 may have multiple sections with different inner diameters in the longitudinal direction of the second cylindrical member 20. The inner diameter of the second cylindrical member 20 may be constant for a length from the distal end 20a to the proximal end 20b of the second cylindrical member 20.

[0083] As shown in Figures 2 and 3, it is preferable that the inner surface 10c of the first cylindrical member 10 and the outer surface 20d of the second cylindrical member 20 are separated.

[0084] As shown in Figures 2 and 3, it is preferable that a gap exists between the inner surface 10c of the first cylindrical member 10 and the outer surface 20d of the second cylindrical member 20. Furthermore, it is more preferable that air is present in this gap.

[0085] As shown in Figure 2, it is preferable that the first connection portion 31, which is the portion where the first cylindrical member 10 and the puncture needle 1 are connected, is located distal to the distal end of the second connection portion 32, which is the portion where the second cylindrical member 20 and the puncture needle 1 are connected. More specifically, it is preferable that the distal end of the first connection portion 31, which is the portion where the first cylindrical member 10 and the puncture needle 1 are connected, is located distal to the distal end of the second connection portion 32, which is the portion where the second cylindrical member 20 and the puncture needle 1 are connected. It is preferable that the first cylindrical member 10 and the puncture needle 1 are in contact at the first connection portion 31. It is preferable that the second cylindrical member 20 and the puncture needle 1 are in contact at the second connection portion 32.

[0086] The elongated member 60 may have a distal end 60a and a proximal end 60b.

[0087] The elongated member 60 may be composed of only one member or of multiple members.

[0088] The elongated member 60 can be made from resin, metal, or other materials listed as capable of forming the cylindrical member 1020. The elongated member 60 may be made entirely of metal, or entirely of resin. The elongated member 60 may be made partly of metal and the other part of resin.

[0089] It is preferable that the elongated member 60 includes a portion made of a resin-containing material. Only a portion of the elongated member 60 may be made of resin, or the entire elongated member 60 may be made of resin.

[0090] The elongated member 60 may have a distal cylindrical portion, a rod-shaped portion positioned proximal to the distal cylindrical portion and having a length in the radial direction y of the puncture needle 1 that is shorter than the distal cylindrical portion, and a proximal cylindrical portion positioned proximal to the rod-shaped portion and having a length in the radial direction y of the puncture needle 1 that is longer than the rod-shaped portion. Preferably, the length of the distal cylindrical portion in the radial direction y of the puncture needle 1 is shorter than the length of the proximal cylindrical portion in the radial direction y of the puncture needle 1. In this case, it is preferable that the distal cylindrical portion is the contact portion 61.

[0091] Preferably, the length of the elongated member 60 in the longitudinal direction x of the puncture needle 1 is longer than the length of the cylindrical member 1020 in the longitudinal direction x of the puncture needle 1. This makes it easier to reduce the amount of liquid remaining in the lumen 1020e of the cylindrical member 1020. However, an configuration in which the length of the elongated member 60 in the longitudinal direction x of the puncture needle 1 is shorter than the length of the cylindrical member 1020 in the longitudinal direction x of the puncture needle 1 is also acceptable.

[0092] The length of the elongated member 60 in the longitudinal direction x of the puncture needle 1 is preferably 60 cm or more, more preferably 70 cm or more, and even more preferably 80 cm or more. The length of the elongated member 60 in the longitudinal direction x of the puncture needle 1 is preferably 3000 cm or less, more preferably 2750 cm or less, and even more preferably 2500 cm or less.

[0093] It is preferable that the distal end 60a of the elongated member 60 can be inserted into the lumen 1e of the puncture needle 1. This makes it easier to reduce the amount of fluid remaining in the lumen 1e of the puncture needle 1, and thus easier to reduce the amount of fluid used. As shown in Figure 2, it is more preferable that the distal end 60a of the elongated member 60 can be inserted into the lumen 1e of the puncture needle 1 when the diameter of the lumen 1e of the puncture needle 1 and the diameter of the lumen 1020e of the cylindrical member 1020 communicating with the lumen 1e of the puncture needle 1 are the same length. However, it is also permissible for the distal end 60a of the elongated member 60 not to be inserted into the lumen 1e of the puncture needle 1.

[0094] It is preferable that the distal end 60a of the elongated member 60 can contact the proximal end 1b of the puncture needle 1. It is also preferable that the distal end of the elongated member 60 can contact the proximal end 1b of the puncture needle 1. This makes it easier to reduce the amount of fluid remaining in the lumen 1020e of the cylindrical member 1020. As shown in Figure 5, it is more preferable that the distal end 60a of the elongated member 60 can contact the proximal end 1b of the puncture needle 1 when the diameter of the lumen 1e of the puncture needle 1 is shorter than the diameter of the lumen 1020e of the cylindrical member 1020 that communicates with the lumen 1e of the puncture needle 1. However, an configuration in which the distal end 60a of the elongated member 60 cannot contact the proximal end 1b of the puncture needle 1 is also acceptable.

[0095] It is preferable that the proximal end 60b of the elongated member 60 is located proximal to the proximal end 1020b of the cylindrical member 1020. This facilitates the sliding of the elongated member 60 in the longitudinal direction x of the puncture needle 1 within the lumen 1020e of the cylindrical member 1020.

[0096] As shown in Figures 2 and 5, it is preferable that the elongated member 60 has a section 62 proximal to the contact portion 61 in which the radial length of the cylindrical member 1020 is shorter than that of the contact portion 61. This makes it easier for the elongated member 60 to slide in the longitudinal direction x of the puncture needle 1 within the lumen 1020e of the cylindrical member 1020.

[0097] As shown in Figures 1, 2, 4, and 5, the puncture catheter 100 may further have a connecting member 40 having a lumen 40e. The connecting member 40 may be connected to the proximal part of the cylindrical member 1020. If the cylindrical member 1020 has a first cylindrical member 10 and a second cylindrical member 20, the puncture catheter 100 may further have a connecting member 40 connected to the proximal parts of the first cylindrical member 10 and the second cylindrical member 20. The lumen 40e of the connecting member 40 is in communication with the lumen 1020e of the cylindrical member 1020, which is in communication with the lumen 1e of the puncture needle 1, and the tip of a syringe may be inserted into the lumen 40e of the connecting member 40. This makes it easier to inject the liquid in the syringe into the lumen 1020e of the cylindrical member 1020. The liquid injected into the lumen 1020e of the cylindrical member 1020 may be transported to the target tissue by passing through the lumen 1e and hole 5 of the puncture needle 1.

[0098] As shown in Figure 2, the proximal end of the third connection portion 33, where the first cylindrical member 10 and the connecting member 40 are connected, may be located more proximal to the proximal end of the fourth connection portion 34, where the second cylindrical member 20 and the connecting member 40 are connected. Although not shown, the proximal end of the third connection portion 33, where the first cylindrical member 10 and the connecting member 40 are connected, may be located more distal to the proximal end of the fourth connection portion 34, where the second cylindrical member 20 and the connecting member 40 are connected. It is preferable that the first cylindrical member 10 and the connecting member 40 are in contact at the third connection portion 33. It is preferable that the second cylindrical member 20 and the connecting member 40 are in contact at the fourth connection portion 34.

[0099] The constituent material of the connecting member 40 is not particularly limited, but for example, polyolefin resins such as polypropylene (PP) and polyethylene (PE), polyester resins such as polyethylene terephthalate (PET), synthetic resins such as polycarbonate resin, ABS resin, and polyurethane resin can be used. [Explanation of Symbols]

[0100] 1: Puncture needle 1a: Distal end 1b: Proximal end 1c: Inner surface 1d: Outer surface 1e: lumen 2: Cylindrical member 2a: Distal end 2b: Proximal end 2e: lumen 3: Helical member 4: Wire rod 5: Hole 1020: Cylindrical member 1020a: Distal end 1020b: Proximal end 1020c: Inner surface 1020d: Outer surface 1020e: lumen 10: First cylindrical member 10a: Distal end 10b: Proximal end 10c: Inner surface 10d: Outer surface 10e: lumen 11: Metal layer 11c: Inner surface 11d: Outer surface 11f: Groove 12: Outer resin layer 13: Inner resin layer 20: Second cylindrical member 20a: Distal end 20b: Proximal end 20c: Inner surface 20d: Outer surface 20e: lumen 31: First connection section 32: Second connection section 33: Third connection section 34: Fourth connection section 40: Connecting member 40e: lumen 60: Long-shaped member 60a: Distal end 60b: Proximal end 61: Contact part 62: Section 100: Puncture catheter

Claims

1. A medical puncture needle having a longitudinal direction and a lumen extending in the longitudinal direction, A cylindrical member having a lumen extending in the longitudinal direction through which liquid passes, and connected to the puncture needle, An elongated member is placed inside the cavity of the cylindrical member and has a length of 50 cm or more in the longitudinal direction, It has, The elongated member has a contact portion that abuts against the inner surface of the cylindrical member, and is slidable in the longitudinal direction within the lumen of the cylindrical member, forming a puncture catheter.

2. The puncture catheter according to claim 1, wherein the tubular member has a metal layer.

3. The puncture catheter according to claim 2, wherein the cylindrical member has an outer resin layer located radially outward of the cylindrical member than the metal layer.

4. The puncture catheter according to claim 2, wherein the cylindrical member has an inner resin layer located radially inward of the cylindrical member than the metal layer.

5. The aforementioned cylindrical member is The first cylindrical member having a lumen extending in the longitudinal direction, A second cylindrical member is disposed within the lumen of the first cylindrical member and has a lumen extending in the longitudinal direction through which liquid passes; It has, The puncture catheter according to claim 1, wherein the elongated member is arranged in the lumen of the second cylindrical member.

6. The puncture catheter according to claim 5, wherein the distal end of the elongated member is insertable into the lumen of the puncture needle.

7. The puncture catheter according to any one of claims 1 to 5, wherein the distal end of the elongated member is capable of contacting the proximal end of the puncture needle.

8. The puncture catheter according to any one of claims 1 to 6, wherein the proximal end of the elongated member is located more proximal to the proximal end of the cylindrical member.

9. The puncture catheter according to any one of claims 1 to 6, wherein the elongated member has a section proximal to the contact portion in which the radial length of the cylindrical member is shorter than that of the contact portion.

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