Warm ethanol extract fermentation liquid

Abstract

While there have been cosmetics and quasi-drugs, including medicated cosmetics, that have traditionally used extracts from Apiaceae plants, including Centella asiatica, such as facial cleansers, makeup removers, lotions, emulsions, creams, serums, beauty oils, cosmetic soaps, body and hair cleansers, and hair conditioners, there have been no products that use a fermented liquid obtained by fermenting Apiaceae plants, including Centella asiatica. [Solution] The fermented liquid obtained in the present invention is obtained by fermenting plants of the Apiaceae family, including Centella asiatica, with yeast after destroying the plant cell walls using warm ethanol extraction. It can be stably incorporated into cosmetics such as facial cleansers, makeup removers, lotions, emulsions, creams, serums, beauty oils, cosmetic soaps, body and hair cleansers, and hair conditioners, as well as quasi-drugs including medicated cosmetics, and as a remover and disinfectant for pathogenic microorganisms including fungi and viruses.

Description

Technical Field

[0001] The present invention relates to a fermentation broth obtained by fermenting a Umbelliferae plant containing Centella asiatica with yeast, which is used in cosmetics such as facial cleansers, makeup removers, lotions, emulsions, creams, beauty essences, beauty oils, toilet soaps, body and hair cleansers, hair conditioners, etc., quasi-drugs including medicinal cosmetics, and agents for removing and disinfecting pathogenic microorganisms including fungi and viruses. Technical Background

[0002] Conventionally, cosmetics such as facial cleansers, makeup removers, lotions, emulsions, creams, beauty essences, beauty oils, toilet soaps, body and hair cleansers, hair conditioners, etc., and quasi-drugs including medicinal cosmetics using an extract of a Umbelliferae plant containing Centella asiatica are known.

[0003] As described above, the existence of cosmetics such as facial cleansers, makeup removers, lotions, emulsions, creams, beauty essences, beauty oils, toilet soaps, body and hair cleansers, hair conditioners, etc., and quasi-drugs including medicinal cosmetics using an extract of a Umbelliferae plant containing Centella asiatica is a known fact. However, as a fermentation broth obtained by fermenting a Umbelliferae plant containing Centella asiatica with yeast in a state where the plant cell wall is destroyed using warm ethanol extraction, there is no case of using it in cosmetics such as facial cleansers, makeup removers, lotions, emulsions, creams, beauty essences, beauty oils, toilet soaps, body and hair cleansers, hair conditioners, etc., and quasi-drugs including medicinal cosmetics, and it is unknown.

[0004] Also, similar to the previous item, there is no case of using a fermentation broth obtained by fermenting a Umbelliferae plant containing Centella asiatica with yeast in a state where the plant cell wall is destroyed using warm ethanol extraction in agents for removing and disinfecting pathogenic microorganisms including fungi and viruses, and it is unknown.

Summary of the Invention

[0005] The present invention aims to provide a fermented liquid obtained by fermenting plants of the Apiaceae family, including Centella asiatica, with yeast after destroying the plant cell walls using warm ethanol extraction, to create cosmetics such as facial cleansers, makeup removers, lotions, emulsions, creams, serums, beauty oils, cosmetic soaps, body and hair cleansers, and hair conditioners, as well as quasi-drugs including medicated cosmetics, and agents for removing and disinfecting pathogenic microorganisms, including fungi and viruses, which have not yet existed.

[0006] Furthermore, the present invention aims to provide a fermented liquid obtained by fermenting plants of the Apiaceae family, including Centella asiatica, with yeast after destroying the plant cell walls using warm ethanol extraction, which can be stably incorporated into cosmetics such as facial cleansers, makeup removers, lotions, emulsions, creams, serums, beauty oils, cosmetic soaps, body and hair cleansers, and hair conditioning agents, as well as quasi-drugs including medicated cosmetics, and agents for removing and disinfecting pathogenic microorganisms including fungi and viruses. [Means for solving the problem]

[0007] This invention uses a fermented liquid obtained by fermenting plants of the Apiaceae family, including Centella asiatica, with yeast after the plant cell walls have been destroyed by warm ethanol extraction.

[0008] The fermented liquid obtained in the previous section is Saccharomyces cerecisiae, Saccharomyces bayanus, Saccharomyces boulardii, Saccharomyces bulderi, Saccharomyces carioanus, Saccharomyces cariocus, Saccharomyces chevalieri, Saccharomyces dairenensis, Saccharomyces ellipsoideus, Saccharomyces florentinus, Saccharomyces kluyveri, Saccharomyces martiniae, Saccharomyces norbensis, Saccharomyces paradoxus, Saccharomyces pastorianus, Saccharomyces spencerorum, Saccharomyces turicensis, Saccharomyces unisporus, Saccharomycesuvarum, Saccharomyces Use yeast from one or more of the following genera: Zonatus, Saccharomycopsis, Candida kefyr, Candida bombicola, Candida utilis, Candida saitoana, Zygosaccharomyces rouxii, Zygosaccharomyces microellipsoides, Kluyveromyces, Schizosaccharomyces pombe, Torulaspora delbrueckii, Pichia anomala, Pichia caribbica, Pseudoxyma tsukubaensis, or Endomyces.

[0009] The fermentation described in the previous section shall be carried out at a temperature of 20°C to 50°C for at least 48 hours.

[0010] After fermentation as described above, heat sterilization is performed at 85°C or higher for at least 30 minutes.

[0011] The fermentation liquid of the present invention is obtained by filtering the supernatant after heat sterilization as described in the previous paragraph. [Effects of the Invention]

[0012] In a state where the plant cell walls of Apiaceae plants, including Centella asiatica, were destroyed by warm ethanol extraction, the following species of the genus Saccharomyces were found: Saccharomyces cerecisiae, Saccharomyces bayanus, Saccharomyces boulardii, Saccharomyces bulderi, Saccharomyces carioanus, Saccharomyces cariocus, Saccharomyces chevalieri, Saccharomyces dairenensis, Saccharomyces ellipsoideus, Saccharomyces florentinus, Saccharomyces kluyveri, Saccharomyces martiniae, Saccharomyces norbensis, Saccharomyces paradoxus, Saccharomyces pastorianus, Saccharomyces spencerorum, Saccharomyces turicensis, and Saccharomyces unisporus, Saccharomycesuvarum, Saccharomyces zonatus, genus Saccharomycopsis, Candida kefyr, Candida bombicola, Candida utilis, Candida saitoana, Zygosaccharomyces rouxii, Zygosaccharomyces microellipsoides, Kluyveromyces, Schizosaccharomyces pombe, Torulaspora delbrueckii, Pichiaanomala, Pichia caribbica, PseudoxymaFermented liquids obtained by fermenting with one or more yeasts from the genera *Tsukubaensis* and *Endomyces* can be stably incorporated into cosmetics such as facial cleansers, makeup removers, lotions, emulsions, creams, serums, beauty oils, cosmetic soaps, body and hair cleansers, and hair conditioners, as well as quasi-drugs including medicated cosmetics.

[0013] Furthermore, when plant cells of the Apiaceae family, including Centella asiatica, were destroyed using warm ethanol extraction, the following species of the genus Saccharomyces were found: Saccharomyces cerecisiae, Saccharomyces bayanus, Saccharomyces boulardii, Saccharomyces bulderi, Saccharomyces carioanus, Saccharomyces cariocus, Saccharomyces chevalieri, Saccharomyces dairenensis, Saccharomyces ellipsoideus, Saccharomyces florentinus, Saccharomyces kluyveri, Saccharomyces martiniae, Saccharomyces norbensis, Saccharomyces paradoxus, Saccharomyces pastorianus, Saccharomyces spencerorum, Saccharomyces turicensis, and Saccharomyces unisporus, Saccharomycesuvarum, Saccharomyces zonatus, genus Saccharomycopsis, Candida kefyr, Candida bombicola, Candida utilis, Candida saitoana, Zygosaccharomyces rouxii, Zygosaccharomyces microellipsoides, Kluyveromyces, Schizosaccharomyces pombe, Torulaspora delbrueckii, Pichia anomala, Pichia caribbica, PseudoxymaFermentation liquids obtained by fermenting with one or more yeasts from the genera *Tsukubaensis* and *Endomyces* can be stably incorporated into disinfectants and fungicides for controlling pathogenic microorganisms, including fungi and viruses.

[0014] Traditionally, Centella asiatica, a plant belonging to the Apiaceae family, has been widely used in the skincare field for its healing effects on wounds and scars, appearing in cosmetics such as facial cleansers, makeup removers, lotions, emulsions, creams, serums, beauty oils, cosmetic soaps, body and hair washes, and hair conditioners, as well as quasi-drugs including medicated cosmetics.

[0015] Furthermore, in the field of traditional Chinese medicine, this plant has long been used as a herbal medicine for the purposes of reducing fever, promoting diuresis, and stopping bleeding.

[0016] Furthermore, in the field of Ayurveda in India, this plant has long been used for treating ulcerative skin diseases caused by leprosy, as well as as a tonic to activate the brain and nerves.

[0017] Furthermore, this plant has been used in the field of phytotherapy in Europe and North America to alleviate scleroderma.

[0018] Based on the information described above, the fermented liquid obtained by the present invention, which is obtained by using yeast to break down the plant cell walls of Apiaceae plants including Centella asiatica using warm ethanol extraction, is suitable as an ingredient to be incorporated into cosmetics such as facial cleansers, makeup removers, lotions, emulsions, creams, serums, beauty oils, cosmetic soaps, body and hair cleansers, and hair conditioners, as well as quasi-drugs including medicated cosmetics. [Modes for carrying out the invention]

[0019] The implementation of the present invention will be described below. [Examples]

[0020] Wash and disinfect the aerial parts including the leaves and stems of Umbellifera plants containing Centella asiatica.

[0021] Destroy the cell walls by contacting the aerial parts including the leaves and stems of Umbellifera plants containing Centella asiatica after washing and disinfection with a 95% aqueous solution of warm ethanol heated to 60 to 65 degrees, and confirm the elution of chlorophyll.

[0022] Ferment the aerial parts including the leaves and stems of Umbellifera plants containing Centella asiatica after cell wall destruction obtained in the previous step using Saccharomyces cerecisiae.

[0023] The fermentation process in the previous step is carried out at a temperature of 35 to 45 degrees Celsius for 168 hours.

[0024] Sterilize the fermentation broth obtained in the previous step by heating at 85 degrees for 60 minutes and filter it.

[0025] The supernatant obtained in the previous step is considered complete.

Industrial Applicability

[0026] The present invention is used in industries for developing and manufacturing cosmetics such as facial cleansers, makeup removers, lotions, emulsions, creams, beauty essences, beauty oils, cosmetic soaps, body and hair cleaning agents, hair conditioning agents, quasi-drugs including medicinal cosmetics, and agents and bactericides for removing pathogenic microorganisms including fungi and viruses.

Claims

1. A fermented liquid obtained by fermenting Centella asiatica with yeast from plants of the Apiaceae family.

2. Cosmetics such as facial cleansers, makeup removers, lotions, emulsions, creams, serums, beauty oils, cosmetic soaps, body and hair cleansers, hair conditioners, and other cosmetics, including quasi-drugs and medicated cosmetics, obtained by incorporating the fermented liquid obtained in claim 1.

3. A removal agent and disinfectant for pathogenic microorganisms, including fungi and viruses, obtained by incorporating the fermented liquid obtained in claim 1.