Oral aerosol

Abstract

This invention relates to an oral aerosol that uses carbon dioxide while providing a comfortable user experience and facilitating extended oral care. [Solution] The following components (A) to (C): (A) Carbon dioxide 0.5% by mass or more (B) Menthol (C) Quaternary ammonium salt An oral aerosol containing [a specific ingredient / material].

Description

Technical Field

[0001] The present invention relates to an oral aerosol agent. :

Background Art

[0002] Conventionally, various products have been developed as agents for application in the oral cavity in order to achieve desired effects. Among them, various preparations filled in aerosol containers together with propellants such as liquefied gas and carbon dioxide have also been developed.

[0003] For example, Patent Document 1 discloses an oral aerosol product mainly composed of a stock solution containing an active ingredient and a propellant containing an inert gas such as oxygen, nitrogen gas, or carbon dioxide gas, and attempts have been made to accurately apply the active ingredient to a desired site in the oral cavity.

Prior Art Documents

Patent Documents

[0004]

Patent Document 1

Summary of the Invention

Problems to be Solved by the Invention

[0005] By the way, when carbon dioxide is used as a propellant, if menthol is contained in the content, when applied in the oral cavity, it brings a more excessive sense of irritation than when other propellants are used, and it has been found by the present inventor that it is difficult to gargle for a long time. However, in the above patent document, no specific consideration has been made on such points, and there is still room for improvement.

[0006] Therefore, the present invention relates to an oral aerosol agent that enables oral care over time with a comfortable feeling of use while not using carbon dioxide.

Means for Solving the Problems

[0007] Therefore, after various studies, the inventors discovered that by including a specific amount of carbon dioxide in combination with menthol and a quaternary ammonium salt, it is possible to obtain an oral aerosol that provides a refreshing carbonated sensation while suppressing excessive irritation.

[0008] In other words, the present invention comprises the following components (A) to (C): (A) Carbon dioxide 0.5% by mass or more (B) Menthol (C) Quaternary ammonium salt This invention provides an oral aerosol containing [a specific ingredient / material]. [Effects of the Invention]

[0009] The oral aerosol agent of the present invention provides a refreshing carbonated sensation in the oral cavity while effectively suppressing excessive irritation, allowing for a comfortable user experience even during prolonged gargling. This makes it easier to dedicate sufficient time to oral care. [Modes for carrying out the invention]

[0010] The present invention will be described in detail below. In this specification, "carbonated cooling sensation" refers to a pleasant sensation that occurs when the oral aerosol agent of the present invention is applied to the oral cavity, in which a crackling and popping sensation from carbon dioxide bubbles and a pleasant, refreshing sensation from menthol spread simultaneously throughout the oral cavity. Furthermore, "excessive irritation" refers to an unpleasant sensation in the mouth that feels like a tingling, numbing, or painful tingling.

[0011] The oral aerosol agent of the present invention is filled into an aerosol container, and the contents of the container are sprayed into the oral cavity from the nozzle of the container. When the oral aerosol agent of the present invention is applied to the oral cavity, the refreshing sensation of carbonation is transmitted to every corner of the oral cavity, and the tingling, numbing sensation and pain are suppressed, allowing for comfortable use and sufficient time to rinse.

[0012] In manufacturing the oral aerosol agent of the present invention, for example, components (B) to (C) are first mixed in advance, and other components are mixed as needed to prepare a liquid (undiluted solution). This liquid is then filled into an aerosol container, and component (A) is sealed in under pressure as needed to create the oral aerosol agent.

[0013] The oral aerosol of the present invention contains 0.5% by mass or more of carbon dioxide as component (A). This, in synergy with components (B) and (C) described later, leads to a pleasant, refreshing micro-vibration that gives way to a powerful, penetrating sensation, greatly contributing to the expression of a carbonated cooling sensation.

[0014] The content of component (A) in the oral aerosol of the present invention is 0.5% by mass or more, preferably 0.8% by mass or more, more preferably 1% by mass or more, even more preferably 1.2% by mass or more, preferably 5% by mass or less, more preferably 4% by mass or less, even more preferably 2.5% by mass or less, and even more preferably 2% by mass or less, from the viewpoint of effectively expressing a carbonated cooling sensation and avoiding the induction of excessive irritation.

[0015] In the oral aerosol agent of the present invention, carbon dioxide may be in a state in which at least a portion of it is dissolved in the liquid in the aerosol container.

[0016] Component (A) may be sealed as a gas when filling the aerosol container, but other gaseous substances may also be included. Examples of such other gaseous substances include nitrogen; liquefied petroleum gases such as isobutane, n-butane, and mixtures thereof; and one or more selected from liquefied gases such as dimethyl ether and isopentane.

[0017] The content of component (A) in 100% by mass of the total gaseous material is preferably 60% by mass or more, more preferably 70% by mass or more, even more preferably 90% by mass or more, and even more preferably 100% by mass, from the viewpoint of effectively achieving both the effect of producing a refreshing carbonated sensation and the effect of suppressing excessive irritation.

[0018] The oral aerosol of the present invention contains menthol as component (B). As a result, component (A) and component (B) act synergistically to greatly contribute to the expression of a carbonated cooling sensation.

[0019] From the viewpoint of contributing to the expression of a carbonated cooling sensation, the content of component (B) in the oral aerosol of the present invention is preferably 0.01% by mass or more, more preferably 0.08% by mass or more, even more preferably 0.15% by mass or more, preferably 1% by mass or less, more preferably 0.7% by mass or less, and even more preferably 0.5% by mass or less. Furthermore, the content of component (B) in the oral aerosol of the present invention is preferably 0.01 to 1% by mass, more preferably 0.08 to 0.7% by mass, and even more preferably 0.15 to 0.5% by mass. Also, from the viewpoint of suppressing excessive irritation, the content of component (B) in the oral aerosol agent of the present invention is preferably 0.01% by mass or more, more preferably 0.04% by mass or more, still more preferably 0.08% by mass or more, preferably 1% by mass or less, more preferably 0.5% by mass or less, and still more preferably 0.24% by mass or less. And the content of component (B) in the oral aerosol agent of the present invention is preferably 0.01 to 1% by mass, more preferably 0.04 to 0.5% by mass, and still more preferably 0.08 to 0.24% by mass.

[0020] The mass ratio ((B) / (A)) of the content of component (B) to the content of component (A) is preferably 0.05 or more, more preferably 0.1 or more, still more preferably 0.18 or more, preferably 3 or less, more preferably 2.5 or less, and still more preferably 2.2 or less from the viewpoint of enhancing the expression effect of the carbonated refreshing feeling. And the mass ratio ((B) / (A)) of the content of component (B) to the content of component (A) is preferably 0.05 to 3, more preferably 0.1 to 2.5, and still more preferably 0.18 to 2.2. Also, the mass ratio ((B) / (A)) of the content of component (B) to the content of component (A) is preferably 0.05 or more, more preferably 0.055 or more, still more preferably 0.06 or more, preferably 3 or less, more preferably 1 or less, and still more preferably 0.18 or less from the viewpoint of suppressing excessive irritation. And the mass ratio ((B) / (A)) of the content of component (B) to the content of component (A) is preferably 0.05 to 3, more preferably 0.055 to 1, and still more preferably 0.06 to 0.18.

[0021] The oral aerosol agent of the present invention contains a quaternary ammonium salt as component (C). Thereby, it can act synergistically with the above components (A) and (B) to effectively relieve excessive irritation and promote the expression of the carbonated refreshing feeling. Specific examples of component (C) include, for example, one or more selected from cetylpyridinium chloride, benzalkonium chloride, benzethonium chloride, lauryltrimethylammonium chloride, stearyldimethylbenzylammonium chloride, myristyltrimethylammonium chloride, cetyltrimethylammonium chloride, and stearyltrimethylammonium chloride. Among them, one or more selected from cetylpyridinium chloride, benzalkonium chloride, and benzethonium chloride are preferable, and cetylpyridinium chloride is more preferable.

[0022] From the viewpoint of contributing to the expression of the carbonated cooling sensation, the content of component (C) in the oral aerosol agent of the present invention is preferably 0.001% by mass or more, more preferably 0.01% by mass or more, still more preferably 0.05% by mass or more, preferably 0.5% by mass or less, more preferably 0.3% by mass or less, and still more preferably 0.2% by mass or less. And the content of component (C) in the oral aerosol agent of the present invention is preferably 0.001~0.5% by mass, more preferably 0.01~0.3% by mass, and still more preferably 0.05~0.2% by mass. Also, from the viewpoint of suppressing excessive irritation, the content of component (C) in the oral aerosol agent of the present invention is preferably 0.001% by mass or more, more preferably 0.01% by mass or more, still more preferably 0.05% by mass or more, preferably 0.5% by mass or less, more preferably 0.45% by mass or less, and still more preferably 0.4% by mass or less. And the content of component (C) in the oral aerosol agent of the present invention is preferably 0.001~0.5% by mass, more preferably 0.01~0.45% by mass, and still more preferably 0.05~0.4% by mass.

[0023] The mass ratio ((C) / (A)) of the content of component (C) to the content of component (A) is preferably 0.005 or more, more preferably 0.05 or more, even more preferably 0.18 or more, preferably 3 or less, more preferably 2.5 or less, and even more preferably 2.2 or less, from the viewpoint of enhancing the effect of expressing a refreshing carbonated sensation and suppressing excessive irritation. Furthermore, the mass ratio ((C) / (A)) of the content of component (C) to the content of component (A) is preferably 0.005 to 3, more preferably 0.05 to 2.5, and even more preferably 0.18 to 2.2.

[0024] The mass ratio ((C) / (B)) of the content of component (C) to the content of component (B) is preferably 0.08 or higher, more preferably 0.2 or higher, even more preferably 0.5 or higher, preferably 5 or lower, more preferably 3 or lower, and even more preferably 2 or lower, from the viewpoint of effectively exhibiting both the effect of producing a refreshing carbonated sensation and the effect of suppressing excessive irritation, and improving suitability for long-term gargling. Furthermore, the mass ratio ((C) / (B)) of the content of component (C) to the content of component (B) is preferably 0.08 to 5, more preferably 0.2 to 3, and even more preferably 0.5 to 2. Furthermore, the mass ratio ((C) / (B)) of the content of component (C) to the content of component (B) is preferably 0.08 or higher, more preferably 0.15 or higher, even more preferably 0.2 or higher, preferably 5 or lower, more preferably 3 or lower, and even more preferably 0.8 or lower, from the viewpoint of effectively exhibiting both the effect of producing a refreshing carbonated sensation and the effect of suppressing excessive irritation, and improving suitability for long-term gargling. The mass ratio ((C) / (B)) of the content of component (C) to the content of component (B) is preferably 0.08 to 5, more preferably 0.15 to 3, and even more preferably 0.2 to 0.8.

[0025] The oral aerosol agent of the present invention preferably further contains water (D). This allows for good dispersion or dissolution of each component filled in the aerosol container, and when sprayed from the nozzle, the entire agent is uniformly and effectively dispersed, thereby promoting the desired effect.

[0026] The content of component (D) in the oral aerosol of the present invention is preferably 50% by mass or more, more preferably 60% by mass or more, even more preferably 70% by mass or more, preferably 97% by mass or less, more preferably 90% by mass or less, and even more preferably 80% by mass or less, from the viewpoint of effectively promoting both the effect of producing a refreshing carbonated sensation and the effect of suppressing excessive irritation.

[0027] From the viewpoint of effectively enhancing the carbonic acid cooling sensation and the suppression of excessive irritation, the oral aerosol of the present invention preferably further contains a nonionic surfactant (E) to improve suitability for prolonged gargling.

[0028] Component (E) specifically includes, for example, polyoxyethylene hydrogenated castor oil; Sucrose fatty acid ester; Sorbitan fatty acid esters such as sorbitan monocaprate, sorbitan monoundecylate, sorbitan monolaurate, sorbitan monotridecylate, sorbitan monomyristate, sorbitan monopalmitate, sorbitan monooleate, sorbitan trioleate, sorbitan tetraoleate, sorbitan sesquioleate, sorbitan monostearate, and sorbitan tristearate; Polyoxyethylene sorbitan fatty acid esters such as polyoxyethylene sorbitan monolaurate, polyoxyethylene sorbitan monomyristate, polyoxyethylene sorbitan monopalmitate, polyoxyethylene sorbitan monostearate, and polyoxyethylene sorbitan monooleate; Glycerin fatty acid esters such as glyceride monostearate; Alkyl glucoside; Polyglycerin fatty acid esters such as decaglyceride monostearate and decaglyceride monomyristate; Polyoxyethylene alkylphenyl ethers such as polyoxyethylene monoalkyl (or alkenyl) ethers, polyoxyethylene polyoxypropylene copolymers, and polyoxyethylene nonylphenyl ethers; Fatty acid alkanolamides such as coconut oil fatty acid diethanolamide; One or more selected from polyethylene glycol fatty acid esters are examples.

[0029] In particular, from the viewpoint of good suitability for prolonged gargling, one or more selected from polyoxyethylene hydrogenated castor oil, sorbitan fatty acid ester, and polyoxyethylene sorbitan fatty acid ester are preferred, and one or more selected from polyoxyethylene hydrogenated castor oil, sorbitan monooleate, sorbitan sesquioleate, sorbitan monostearate, polyoxyethylene sorbitan monopalmitate, polyoxyethylene sorbitan monostearate, and polyoxyethylene sorbitan monooleate are more preferred.

[0030] The content of component (E) in the oral aerosol of the present invention is preferably 0.03% by mass or more, more preferably 0.15% by mass or more, even more preferably 0.24% by mass or more, preferably 3% by mass or less, more preferably 1.5% by mass or less, even more preferably 0.9% by mass or less, and even more preferably 0.5% by mass or less, from the viewpoint of enhancing the effect of expressing a refreshing carbonated sensation and the effect of suppressing excessive irritation.

[0031] The mass ratio ((E) / (B)) of the content of component (E) to the content of component (B) is preferably 0.1 or more, more preferably 0.5 or more, even more preferably 0.8 or more, preferably 15 or less, more preferably 8 or less, and even more preferably 2.8 or less, from the viewpoint of the effect of expressing a refreshing carbonated sensation. Furthermore, the mass ratio ((E) / (B)) of the content of component (E) to the content of component (B) is preferably 0.1 to 15, more preferably 0.5 to 8, and even more preferably 0.8 to 2.8. Furthermore, the mass ratio ((E) / (B)) of the content of component (E) to the content of component (B) is preferably 0.1 or more, more preferably 0.5 or more, even more preferably 1.2 or more, preferably 15 or less, more preferably 8 or less, and even more preferably 5 or less, from the viewpoint of enhancing the effect of suppressing excessive irritation. The mass ratio ((E) / (B)) of the content of component (E) to the content of component (B) is preferably 0.1 to 15, more preferably 0.5 to 8, and even more preferably 1.2 to 5.

[0032] The oral aerosol agent of the present invention may contain ethanol (F) from the viewpoint of enhancing the effect of suppressing excessive irritation and from the viewpoint of properly dispersing or dissolving each component filled in the aerosol container. The content of component (F) in the oral aerosol agent of the present invention is preferably 0.2% by mass or more, more preferably 1% by mass or more, even more preferably 1.6% by mass or more, preferably 10% by mass or less, more preferably 6% by mass or less, and even more preferably 4% by mass or less. Furthermore, the content of component (F) in the oral aerosol agent of the present invention is preferably 0.2 to 10% by mass, more preferably 1 to 6% by mass, and even more preferably 1.6 to 4% by mass.

[0033] The mass ratio ((F) / (B)) of the content of component (F) to the content of component (B) is preferably 2 or more, more preferably 4 or more, even more preferably 6 or more, even more preferably 8 or more, preferably 200 or less, more preferably 100 or less, even more preferably 25 or less, and even more preferably 23 or less, from the viewpoint of enhancing the effect of suppressing excessive irritation. Furthermore, the mass ratio ((F) / (B)) of the content of component (F) to the content of component (B) is preferably 2 to 200, more preferably 4 to 100, even more preferably 6 to 25, and even more preferably 8 to 23. Furthermore, the mass ratio ((F) / (B)) of the content of component (F) to the content of component (B) is preferably 2 or more, more preferably 3 or more, even more preferably 4 or more, preferably 200 or less, more preferably 100 or less, and even more preferably 15 or less, from the viewpoint of the effect of expressing a refreshing carbonated sensation. The mass ratio ((F) / (B)) of the content of component (F) to the content of component (B) is preferably 2 to 200, more preferably 3 to 100, and even more preferably 4 to 15.

[0034] The oral aerosol of the present invention may contain one or more polyols (G) selected from glycerin, ethylene glycol, butylene glycol, propylene glycol, sorbitol, xylitol, erythritol, reduced palatinose, and mannitol. In particular, one or more polyols (G) selected from glycerin, butylene glycol, propylene glycol, sorbitol, xylitol, erythritol, reduced palatinose, and mannitol are preferred as such component (G), one or more polyols (G) selected from glycerin, sorbitol, xylitol, and erythritol are more preferred, and one or more polyols (G) selected from glycerin, sorbitol, and erythritol are even more preferred.

[0035] The content of component (G) in the oral aerosol of the present invention is preferably 5% by mass or more, more preferably 10% by mass or more, even more preferably 15% by mass or more, preferably 45% by mass or less, more preferably 35% by mass or less, and even more preferably 25% by mass or less, from the viewpoint of ensuring the effect of exhibiting a carbonated cooling sensation and the effect of suppressing excessive irritation. Furthermore, the content of component (G) in the oral aerosol of the present invention is preferably 5 to 45% by mass, more preferably 10 to 35% by mass, and even more preferably 15 to 25% by mass.

[0036] The oral aerosol agent of the present invention may contain a monohydric alcohol (H) with 12 to 22 carbon atoms, in order to form an α-gel and ensure the expression of a carbonated cooling sensation and the suppression of excessive irritation.

[0037] The number of carbon atoms in component (H) is 12 or more, preferably 14 or more, more preferably 16 or more, and 22 or less, preferably 20 or less, and more preferably 18 or less. Specifically, such component (H) is preferably one or more selected from cetanol, stearyl alcohol, lauryl alcohol, myristyl alcohol, and behenyl alcohol, more preferably one or two selected from cetanol and stearyl alcohol, even more preferably component (H) contains at least stearyl alcohol, and even more preferably contains both cetanol and stearyl alcohol.

[0038] The content of component (H) in the oral aerosol of the present invention is preferably 0.6% by mass or more, more preferably 0.8% by mass or more, even more preferably 1.5% by mass or more, preferably 10% by mass or less, more preferably 8% by mass or less, and even more preferably 5% by mass or less, from the viewpoint of ensuring the expression of a carbonated cooling sensation effect and the suppression of excessive irritation. Furthermore, the content of component (H) in the oral aerosol of the present invention is preferably 0.6 to 10% by mass, more preferably 0.8 to 8% by mass, and even more preferably 1.5 to 5% by mass.

[0039] In addition to the above-mentioned components, the oral aerosol agent of the present invention may contain surfactants other than the above-mentioned components; fragrances other than component (B); pH adjusters, preservatives, medicinal ingredients, dyes, etc., to the extent that they do not impair the effects of the present invention.

[0040] When pressurizing the oral aerosol agent of the present invention when filling an aerosol container, the pressure inside the aerosol container is preferably 0.3 to 1 MPa, and more preferably 0.5 to 0.95 MPa, at 25°C. When applying the oral aerosol agent of the present invention to the oral cavity, the amount of the oral aerosol agent of the present invention applied per use is preferably 1 to 20 g, and more preferably 3 to 10 g.

[0041] With regard to the embodiments described above, the present invention further discloses the following oral aerosols. [1] The following components (A) to (C): (A) Carbon dioxide 0.5% by mass or more (B) Menthol (C) Quaternary ammonium salt An oral aerosol containing [a specific ingredient / material]. [2] The oral aerosol agent according to [1] above, wherein the content of component (A) is preferably 0.8% by mass or more, more preferably 1% by mass or more, even more preferably 1.2% by mass or more, preferably 5% by mass or less, more preferably 4% by mass or less, even more preferably 2.5% by mass or less, and even more preferably 2% by mass or less. [3] The oral aerosol agent according to [1] or [2] above, wherein the content of component (A) in 100% by mass of the total gaseous body is preferably 60% by mass or more, more preferably 70% by mass or more, even more preferably 90% by mass or more, and even more preferably 100% by mass.

[0042] [4] An oral aerosol agent according to any one of [1] to [3] above, wherein the content of component (B) is preferably 0.01% by mass or more, more preferably 0.08% by mass or more, even more preferably 0.15% by mass or more, preferably 1% by mass or less, more preferably 0.7% by mass or less, and even more preferably 0.5% by mass or less. [5] An oral aerosol agent according to any one of the above [1] to [4], wherein the mass ratio ((B) / (A)) of the content of component (B) to the content of component (A) is preferably 0.05 or more, more preferably 0.1 or more, even more preferably 0.18 or more, preferably 3 or less, more preferably 2.5 or less, and even more preferably 2.2 or less. [6] The oral aerosol preparation according to any one of the above [1] to [5], wherein component (C) is preferably one or more selected from cetylpyrinidium chloride, benzalkonium chloride, benzethonium chloride, lauryltrimethylammonium chloride, stearyldimethylbenzylammonium chloride, myristyltrimethylammonium chloride, cetyltrimethylammonium chloride, and stearyltrimethylammonium chloride, more preferably one or more selected from cetylpyrinidium chloride, benzalkonium chloride, and benzethonium chloride, and even more preferably cetylpyrinidium chloride. [7] An oral aerosol agent according to any one of the above [1] to [6], wherein the content of component (C) is preferably 0.001% by mass or more, more preferably 0.01% by mass or more, even more preferably 0.05% by mass or more, preferably 0.5% by mass or less, more preferably 0.3% by mass or less, and even more preferably 0.2% by mass or less.

[0043] [8] An oral aerosol agent according to any one of the above [1] to [7], wherein the mass ratio ((C) / (A)) of the content of component (C) to the content of component (A) is preferably 0.005 or more, more preferably 0.05 or more, even more preferably 0.18 or more, preferably 3 or less, more preferably 2.5 or less, and even more preferably 2.2 or less. [9] An oral aerosol agent according to any one of the above [1] to [8], wherein the mass ratio ((C) / (B)) of the content of component (C) to the content of component (B) is preferably 0.08 or more, more preferably 0.2 or more, even more preferably 0.5 or more, preferably 5 or less, more preferably 3 or less, and even more preferably 2 or less.

[10] An oral aerosol agent according to any one of the above [1] to [9], further containing water (D), wherein the content of such component (D) is preferably 50% by mass or more, more preferably 60% by mass or more, even more preferably 70% by mass or more, preferably 97% by mass or less, more preferably 90% by mass or less, and even more preferably 80% by mass or less.

[11] The oral aerosol agent according to any one of the above [1] to

[10] , further containing a nonionic surfactant (E), wherein the content of such component (E) is preferably 0.03% by mass or more, more preferably 0.15% by mass or more, even more preferably 0.24% by mass or more, preferably 3% by mass or less, more preferably 1.5% by mass or less, even more preferably 0.9% by mass or less, and even more preferably 0.5% by mass or less.

[12] The oral aerosol preparation according to

[11] above, wherein the mass ratio ((E) / (B)) of the content of component (E) to the content of component (B) is preferably 0.1 or more, more preferably 0.5 or more, even more preferably 0.8 or more, preferably 15 or less, more preferably 8 or less, and even more preferably 2.8 or less.

[0044]

[13] An oral aerosol agent according to any one of the above [1] to

[12] , further containing ethanol (F), wherein the content of such component (F) is preferably 0.2% by mass or more, more preferably 1% by mass or more, even more preferably 1.6% by mass or more, preferably 10% by mass or less, more preferably 6% by mass or less, and even more preferably 4% by mass or less.

[14] The oral aerosol preparation according to

[13] above, wherein the mass ratio ((F) / (B)) of the content of component (F) to the content of component (B) is preferably 2 or more, more preferably 4 or more, even more preferably 6 or more, even more preferably 8 or more, preferably 200 or less, more preferably 100 or less, even more preferably 25 or less, and even more preferably 23 or less.

[15] An oral aerosol agent according to any one of the above [1] to

[14] , further containing one or more polyols (G) selected from glycerin, ethylene glycol, butylene glycol, propylene glycol, sorbitol, xylitol, erythritol, reduced palatinose, and mannitol, wherein the content of such component (G) is preferably 5% by mass or more, more preferably 10% by mass or more, even more preferably 15% by mass or more, preferably 45% by mass or less, more preferably 35% by mass or less, and even more preferably 25% by mass or less.

[16] The oral aerosol agent according to any one of the above [1] to

[15] , further containing a monohydric alcohol (H) having 12 to 22 carbon atoms, wherein the content of such component (H) is preferably 0.6% by mass or more, more preferably 0.8% by mass or more, even more preferably 1.5% by mass or more, preferably 10% by mass or less, more preferably 8% by mass or less, and even more preferably 5% by mass or less. [Examples]

[0045] The present invention will be described in detail below based on examples. Unless otherwise specified in the table, the content of each component is expressed in mass percent.

[0046] [Examples 1-10, Comparative Examples 1-3] Following the formulations shown in Table 1, each component except component (A) was mixed to prepare a liquid (stock solution). The resulting liquid (stock solution) and component (A) were then adjusted to a ratio of 100% by mass (83.3 g). This mixture was then sealed in an aerosol container (manufactured by Takeuchi Press Co., Ltd.) at a pressure of 0.9 MPa at 25°C to produce each of the formulations. The obtained agents were used to perform the following evaluations. The results are shown in Table 1.

[0047] Evaluation of the refreshing sensation from carbonation, ease of gargling, and suppression of excessive irritation. Four expert panelists sprayed 5g of each formulation into their mouths through the nozzle. Then, within 10 seconds of spraying, they performed a sensory evaluation of the following evaluation items: "carbonated cooling sensation," "ease of gargling," and "suppression of excessive irritation." The average value of each evaluation was used as the evaluation result.

[0048] • Evaluation criteria for carbonated refreshing sensation 4: I felt a very strong carbonation-like refreshing sensation. 3: I felt a refreshing sensation from the carbonation. 2: I felt a slight carbonation-like refreshing sensation. 1: I didn't feel any carbonation or refreshing sensation.

[0049] • Criteria for evaluating ease of gargling 4: It was very easy to gargle with. 3: It was easy to gargle with. 2: It was slightly easier to gargle with. 1: It was difficult to gargle with.

[0050] • Evaluation criteria for suppressing excessive irritation 5: I didn't feel any excessive irritation at all. 4: I hardly felt any excessive irritation. 3: I felt a slight excessive irritation, but it was within an acceptable range. 2: I felt an excessive sensation. 1: I felt an excessive sensation of irritation.

[0051] [Table 1]

[0052] Table 2 shows examples of formulations for the oral aerosol of the present invention.

[0053] [Table 2]

Claims

1. The following components (A) to (C): (A) Carbon dioxide 0.5% by mass or more (B) Menthol (C) Quaternary ammonium salts An oral aerosol containing [a specific ingredient / material].

2. The oral aerosol agent according to claim 1, wherein the mass ratio ((C) / (B)) of the content of component (C) to the content of component (B) is 0.08 or more and 5 or less.

3. Furthermore, the oral aerosol agent according to claim 1 or 2 further contains water (D).

4. Furthermore, the oral aerosol agent according to claim 1 or 2, wherein it contains a nonionic surfactant (E), and the mass ratio ((E) / (B)) of the content of component (E) to the content of component (B) is 0.1 or more and 15 or less.

5. Furthermore, the oral aerosol agent according to claim 1 or 2, wherein it contains ethanol (F), and the mass ratio ((F) / (B)) of the content of component (F) to the content of component (B) is 2 or more and 200 or less.

6. The oral aerosol according to claim 1 or 2, further comprising one or more polyols (G) selected from glycerin, ethylene glycol, butylene glycol, propylene glycol, sorbitol, xylitol, erythritol, reduced palatinose, and mannitol.

7. The oral aerosol agent according to claim 3, wherein the content of component (D) is 50% by mass or more and 97% by mass or less.

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