Water-based oil-based external formulation

Abstract

The present invention provides an oil-in-water type topical composition that excels in suppressing squeaking and dryness during use, as well as the formation of residue caused by friction with the skin. [Solution] Prepare an oil-in-water type topical composition containing (A) 8% by mass or more of an ultraviolet scattering agent, (B) a polyglycerol fatty acid ester having at least one hydroxyl group in the fatty acid, and (C) a nonpolar oil.

Description

Technical Field

[0005] , , ,

[0001] The present invention relates to an oil-in-water type external composition.

Background Art

[0002] In order to protect the human body from harmful light rays such as ultraviolet rays in various scenes of daily life, attempts have been made to incorporate an ultraviolet ray protecting agent into an oil-in-water type external composition. When incorporating an ultraviolet ray protecting agent, there were many difficulties in realizing an oil-in-water type external composition that could be used comfortably.

[0003] Regarding an oil-in-water type emulsified composition containing a metal oxide-based ultraviolet ray scattering agent, a clay mineral-based hydrophilic thickener, a hydrophilic thickener, a nonionic surfactant, an anionic surfactant, and an aqueous component, attempts have been made to achieve suppression of stickiness peculiar to the hydrophilic thickener, suppression of reduction in viscosity due to long-term storage, and desired usability and stability of the emulsified state (Patent Document 1), but many problems remain in order for users to use it comfortably in various scenes of daily life.

Prior Art Documents

Patent Documents

[0004]

Patent Document 1

Summary of the Invention

Problems to be Solved by the Invention

[0005] The present inventor has found that in a composition containing 8% by mass or more of an ultraviolet ray scattering agent in an oil-in-water type external composition, depending on the composition, when brought into contact with the living body surface, there are new problems such as a squeaking feeling, the generation of various lumps (debris) due to rubbing with the skin, or the generation of a dry feeling over time. If the composition causes such problems during use, the user cannot use it comfortably, and it is impossible to apply the composition containing the ultraviolet ray scattering agent over a wide area of the living body surface to protect against ultraviolet rays.

[0006] The object of the present invention is to provide an oil-in-water type topical composition that is excellent at suppressing the squeaking and dryness sensations during use, as well as the formation of crumbly clumps (residue) caused by friction with the skin. [Means for solving the problem]

[0007] The inventors have found that an oil-in-water type topical composition containing (A) 8% by mass or more of an ultraviolet scattering agent, (B) a polyglycerin fatty acid ester having at least one hydroxyl group in the fatty acid, and (C) a non-polar oil suppresses the feeling of squeaking and dryness during use, and also suppresses the generation of residue caused by friction with the skin.

[0008] The present invention was completed based on the above findings and provides the following oil-in-water type external composition.

[0009] In other words, the present invention is [1] The present invention provides an oil-in-water type topical composition containing (A) 8% by mass or more of an ultraviolet scattering agent, (B) a polyglycerol fatty acid ester having at least one hydroxyl group in the fatty acid, and (C) a nonpolar oil. In a preferred embodiment, the present invention provides the following compositions and methods. [2] Furthermore, the oil-in-water type external composition according to [1] contains (D) a water-soluble polysaccharide. [3] Furthermore, the oil-in-water type external composition according to [1] or [2], further comprising (E) a higher alcohol having 14 to 20 carbon atoms. [4] The oil-in-water type topical composition according to [1] or [2], wherein the (A) ultraviolet scattering agent is hydrophobized with an alkoxysilane. [5] An oil-in-water external composition according to [1] or [2], wherein component (A) and component (B) are dispersed in an oil phase. [6] The topical skin composition according to [1] or [2], wherein the ratio of the total content of component (B) to component (A) is 0.005 to 1 part by mass. [7] A topical skin composition according to [1] or [2] that substantially does not contain an ultraviolet light absorbing agent. [8] Furthermore, the oil-in-water type external composition according to [1] or [2] contains polyglycerin fatty acid esters other than (F) and (B). [9] The oil-in-water type topical composition according to [8], wherein the fatty acid of component (F) has a branched chain.

[10] An oil-in-water topical composition according to [1] or [2], which is substantially free of polyoxyethylene fatty acid esters.

[11] A method for suppressing squeaky feeling, dryness, or the generation of residue due to friction with the skin during application by coexisting (A) an ultraviolet scattering agent in an amount of 8% by mass or more, (B) a polyglycerin fatty acid ester having at least one hydroxyl group in the fatty acid, and (C) a nonpolar oil in an oil-in-water type topical composition. [Effects of the Invention]

[0010] The oil-in-water type topical composition according to the present invention suppresses squeaky and dry sensations and inhibits the formation of crumbly clumps (residue) when applied to living organisms. [Modes for carrying out the invention]

[0011] The embodiments for carrying out the present invention will be described in detail below. However, the present invention is not limited to the following embodiments.

[0012] In this specification, "salt" is not particularly limited as long as it is medically, pharmacologically, or physiologically acceptable. Specifically, this includes basic salts such as alkali metal salts, alkaline earth metal salts, salts with inorganic bases such as typical metal salts, and salts with organic bases. "Salt" also includes solvates and hydrates of salts.

[0013] [1. Oil-in-water external composition] The oil-in-water type external composition according to this embodiment contains 8% by mass or more of (A) an ultraviolet ray scattering agent (also simply referred to as “component (A)”), (B) a polyglycerol fatty acid ester having at least one or more hydroxyl groups in the fatty acid (also simply referred to as “component (B)”), and (C) a nonpolar oil (also simply referred to as “component (C)”), and is an oil-in-water type external composition.

[0014] <(A) Ultraviolet ray scattering agent> The ultraviolet ray scattering agent may be used alone or in combination of two or more. It is not particularly limited as long as it is used in cosmetics, pharmaceuticals, and foods. Examples of component (A) include one or more metal oxides selected from the group consisting of zinc oxide, titanium oxide, cerium oxide, and zirconium oxide. The shape of the particles of component (A) may be any of spherical, plate-like, spindle-like, needle-like, etc. Titanium oxide may be of the rutile type or the anatase type, and the rutile type is preferred. It is not particularly limited by the shape such as spherical, plate-like, needle-like, etc., the particle diameter such as smoke-like, fine particles, pigment grade, etc., the particle structure such as porous or non-porous, etc., and may be surface-treated by a known surface treatment method. Commercially available products can be used as component (A).

[0015] Examples of the surface treatment of component (A) include silicone treatment; alkylalkoxysilane treatment; fatty acid treatment; treatment with fluorine-containing compounds such as perfluoroalkyl phosphate ester, perfluoroalcohol, perfluoroalkylalkoxysilane; amino acid treatment such as N-acylglutamic acid; hydrophobic treatment such as alkyl phosphate ester treatment. From the viewpoint of more significantly exhibiting the effects of the present invention, for example, alkylalkoxysilane treatment, silicone treatment, and fatty acid treatment are preferred, alkylalkoxysilane treatment is more preferred, and triethoxycaprylylsilane treatment is particularly preferred. The total amount of the surface treatment agent is not particularly limited, but from the viewpoint of more significantly exhibiting the effects of the present invention, 1 to 50% by mass is preferred, and 5 to 40% by mass is more preferred with respect to the ultraviolet ray scattering agent.

[0016] The average particle diameter of the component (A) is preferably 1 to 1000 nm, more preferably 1 to 500 nm, still more preferably 3 to 200 nm, even more preferably 5 to 200 nm, particularly preferably 5 to 150 nm, and most preferably 7 to 100 nm, from the viewpoint of more significantly achieving the effects according to the present invention. Here, the average particle diameter represents the average particle diameter in the volume-based particle size distribution measured using a laser diffraction / scattering particle size distribution measuring device.

[0017] The content of the component (A) in the oil-in-water type external composition according to the present embodiment is not particularly limited and is appropriately set according to the type of the component (A), the types and contents of other compounding components, the use and dosage form of the oil-in-water type external composition, and the like. As the content of the component (A), from the viewpoint of more significantly achieving the ultraviolet protection effect and the effects of the present invention in a well-balanced manner, for example, based on the total amount of the oil-in-water type external composition, 8% by mass or more is preferable, 9% by mass or more is more preferable, 10% by mass or more is still more preferable, 11% by mass or more is even more preferable, 13% by mass or more is even more preferable, 15% by mass or more is even more preferable, and 18% by mass or more is particularly preferable. Further, the content of the component (A) is preferably 45% by mass or less, more preferably 40% by mass or less, still more preferably 35% by mass or less, even more preferably 30% by mass or less, and particularly preferably 25% by mass or less, based on the total amount of the oil-in-water type external composition.

[0018] <(B) Polyglycerol fatty acid ester having at least one or more hydroxyl groups in the fatty acid> The polyglycerol fatty acid ester having one or more hydroxyl groups in the fatty acid may be used alone or in combination of two or more. It is not particularly limited as long as it is used in cosmetics, pharmaceuticals, and foods. Commercially available products can also be used. Such a component (B) is considered to be able to hold much more water (several times as much in mass) than its own weight, further enclose the ultraviolet scattering agent, and adsorb to both the surface of the ultraviolet scattering agent and the surface of the skin. Therefore, it can also contribute to the improvement of the usability of the composition and the feeling of adhesion to the skin. (B) Among the components, examples that exhibit the effects of the present invention more significantly include polyglyceryl-10 pentahydroxystearate, polyglyceryl-6 pentahydroxystearate, polyglyceryl-6 polyhydroxystearate, polyglyceryl-6 polyricinoleate, polyglyceryl-5 polyricinoleate, polyglyceryl-10 polyricinoleate, polyglyceryl-4 polyricinoleate, and (dimer dilinoleate / stearic acid / hydroxystearate) polyglyceryl-10. Of these, (dimer dilinoleate / stearic acid / hydroxystearate) polyglyceryl-10 is particularly preferred. Specific examples of commercially available products include NIKKOL GS-WHO (Nikko Chemicals Co., Ltd.), NIKKOL Decaglyn 5-HS (Nikko Chemicals Co., Ltd.), NIKKOL Hexaglyn PR-15 (Nikko Chemicals Co., Ltd.), NIKKOL Decaglyn PR-20 (Nikko Chemicals Co., Ltd.), Sunsoft No. 818SK-C (Taiyo Kagaku Co., Ltd.), Sunsoft No. 818R-C (Taiyo Kagaku Co., Ltd.), and SY Glister CR-310 (Sakamoto Pharmaceutical Co., Ltd.).

[0019] The content of component (B) in the oil-in-water type topical composition according to this embodiment is not particularly limited and is set appropriately depending on the type of component (B), the types and content of other compounding components, the use and formulation form of the oil-in-water type topical composition, etc. As for the content of component (B), from the viewpoint of more significantly exhibiting the effects of the present invention, for example, it is preferably 0.1% by mass or more, more preferably 0.5% by mass or more, and even more preferably 1% by mass or more, based on the total amount of the oil-in-water type topical composition. Furthermore, the content of component (B) is preferably 5% by mass or less, more preferably 4.5% by mass or less, and even more preferably 4% by mass or less, based on the total amount of the oil-in-water type topical composition.

[0020] In the oil-in-water type external composition according to this embodiment, the ratio of the total content of component (B) to component (A) is not particularly limited, but preferably, per 1 part by mass of component (A), component (B) is 0.005 parts by mass or more, 0.01 parts by mass or more, 0.02 parts by mass or more, 0.04 parts by mass or more, 1 part by mass or less, 0.5 parts by mass or less, 0.3 parts by mass or less, and 0.1 parts by mass or less.

[0021] It is preferable that both component (A) and component (B) are dispersed in the oil phase.

[0022] <(C) Non-polar oil> Nonpolar oils may be used individually or in combination of two or more types. They are not particularly limited as long as they are used in cosmetics, pharmaceuticals, or food products. Commercially available products may also be used. (C) Components include hydrocarbon oils and silicone oils. Specifically, these include squalane, plant-derived squalane, squalene, α-olefin oligomer, liquid paraffin (refractive index 1.47), mineral oil, hydrogenated polyolefin, ozokerite, ceresin, microcrystalline wax, paraffin wax, polyethylene wax, polyethylene / polypropylene wax, pristane and polyisoprene, n-decane, n-undecane, n-dodecane, isodecane, isododecane, isohexane, cyclohexane, isohexadecane, n-octane, isooctane, n-nonane, petrolatum, and light liquid isoparaffin. Examples include hydrocarbon oils such as isoparaffin, polybutene, polyisobutene, hydrogenated polyisobutene, and hydrogenated polydecene, and silicone oils such as dimethylpolysiloxane (dimethicone), methylphenylpolysiloxane, methylhydrogenpolysiloxane, tetramethyltetrahydrogenpolysiloxane, PCA dimethicone, cyclomethicone, caprylyl methicone, diphenylsiloxyphenyl trimethicone, octamethylcyclotetrasiloxane, decamethylcyclopentasiloxane, and dodecamethylcyclohexasiloxane. Specific examples of commercially available products include squalane (Squalane: Nikko Chemicals Co.), light liquid paraffin (Moresco White P-70: Moresco), heavy liquid paraffin (Moresco White P-350: Moresco), hydrogenated polyisobutene (Pearlream series: NOF Corporation), hydrogenated polyolefin (Sincelaan 4SP: Nikko Chemicals Co.), and hydrogenated polydecene (Silkflo 364 NF, Silkflo 366 NF: LIPO CHEMICAL).

[0023] The content of component (C) in the topical composition according to this embodiment is not particularly limited and is set appropriately depending on the type of component (C), the types and content of other compounding components, the use and formulation form of the oil-in-water topical composition, etc. As for the content of component (C), from the viewpoint of more significantly exhibiting the effects of the present invention, for example, based on the total amount of the oil-in-water topical composition, the total content of component (C) may be 0.1% by mass or more, preferably 1% by mass or more, more preferably 3% by mass or more, and even more preferably 5% by mass or more. Also, the content of component (B) may be 50% by mass or less, based on the total amount of the oil-in-water topical composition, preferably 45% by mass or less, more preferably 40% by mass or less, even more preferably 35% by mass or less, even more preferably 30% by mass or less, particularly preferably 25% by mass or less, and most preferably 20% by mass or less. (C) If component is a hydrocarbon oil, the total content of hydrocarbon oil may be 1 to 50% by mass, preferably 5 to 50% by mass, more preferably 5 to 40% by mass, even more preferably 5 to 30% by mass, and most preferably 5 to 20% by mass, based on the total amount of the oil-in-water type topical composition. (C) If component is a silicone oil, the total content of silicone oil may be 0.1 to 50% by mass, preferably 0.1 to 40% by mass, more preferably 0.1 to 30% by mass, even more preferably 0.1 to 25% by mass, and most preferably 5 to 20% by mass, based on the total amount of the oil-in-water type topical composition.

[0024] In the oil-in-water type external composition according to this embodiment, the ratio of the total content of component (C) to component (A) is not particularly limited, but the amount of component (C) is preferably 0.005 parts by mass or more, 0.01 parts by mass or more, 0.1 parts by mass or more, 0.5 parts by mass or more, 5 parts by mass or less, 3 parts by mass or less, and 1 part by mass or less, with respect to 1 part by mass of component (A).

[0025] In the oil-in-water type external composition according to this embodiment, the ratio of the total content of component (C) to component (B) is not particularly limited, but preferably, per 1 part by mass of component (B), component (C) is 0.05 parts by mass or more, 0.1 parts by mass or more, 1 part by mass or more, 5 parts by mass or more, 10 parts by mass or more, 500 parts by mass or less, 100 parts by mass or less, 50 parts by mass or less, and 30 parts by mass or less.

[0026] <(D) Water-soluble polysaccharide> The oil-in-water type external composition according to this embodiment may contain (D) a water-soluble polysaccharide in addition to components (A), (B), and (C). Water-soluble polysaccharides may be used individually or in combination of two or more types. They are not particularly limited as long as they are used in cosmetics, pharmaceuticals, or food products. Furthermore, water-soluble polysaccharides may be naturally derived or obtained through chemical synthesis.

[0027] Examples of water-soluble polysaccharides include gums (gellan gum, xanthan gum, sclerotium gum, locust bean gum, biosaccharide gum, tamarind gum, quince seed gum, acacia gum, carrageenan, tara gum, guar gum, galactan, tragacanth gum, curdlan, succinoglucan, etc.); heparin-like substances; alginates (alginic acid, sodium alginate, propylene glycol alginate, etc.); agar (including agarose); pectin; pullulan; and mannan.

[0028] In particular, one or more selected from the group consisting of gums, heparinoids, alginates, agar, pectin, pullulan, and mannan are preferred, and one or more selected from the group consisting of gellan gum, xanthan gum, sclerotium gum, gum arabic, tamarind seed gum, biosaccharide gum, carrageenan, heparinoids, alginates, agar, pectin, and pullulan are more preferred, and gellan gum, xanthan gum, gum arabic, sclerotium One or more selected from the group consisting of thium gum, carrageenan, heparin-like substances, alginates, agar, pectin, and pullulan is more preferable, one or more selected from the group consisting of gellan gum, xanthan gum, gum arabic, heparin-like substances, alginates, agar, and pectin is even more preferable, and one or more selected from the group consisting of gellan gum, xanthan gum, gum arabic, heparin-like substances, and agar is particularly preferable.

[0029] The total content of component (D) in the external composition according to this embodiment is not particularly limited and can be set as appropriate depending on the type of water-soluble polysaccharide, the types of other components, etc. However, from the viewpoint of improving the stability of the composition, it is preferably 0.01% by mass or more, more preferably 0.05% by mass or more, even more preferably 0.1% by mass or more, even more preferably 0.5% by mass or more, and even more preferably 0.8% by mass or more, based on the total amount of the oil-in-water type external composition. (D) The total content of component (D) is preferably 10% by mass or less, more preferably 8% by mass or less, even more preferably 5% by mass or less, even more preferably 3% by mass or less, and particularly preferably 2% by mass or less, based on the total amount of the oil-in-water type topical composition, from the viewpoint of providing a good user experience.

[0030] <(E) Higher alcohols with 14-20 carbon atoms> The oil-in-water type external composition according to this embodiment may contain (E) a higher alcohol having 14 to 20 carbon atoms, in addition to components (A), (B), and (C). Higher alcohols with 14 to 20 carbon atoms may be used individually or in combination of two or more. They are not particularly limited as long as they are used in cosmetics, pharmaceuticals, or food products.

[0031] Examples of higher alcohols having 14 to 20 carbon atoms include straight-chain saturated alcohols (solid at room temperature) such as myristyl alcohol, cetanol, cetostearyl alcohol, stearyl alcohol, and arachidyl alcohol; unsaturated alcohols (liquid at room temperature) such as oleyl alcohol; or hexyldecanol, isostearyl alcohol, octyldodecanol, etc. From the viewpoint of stability, stearyl alcohol or cetanol is preferred as the higher alcohol, and cetanol is particularly preferred.

[0032] The total content of component (E) in the topical composition according to this embodiment is not particularly limited and can be appropriately set depending on the type of water-soluble polysaccharide, the types of other components, etc. However, from the viewpoint of improving the stability of the composition, it is preferably 0.1% by mass or more, more preferably 0.5% by mass or more, even more preferably 1% by mass or more, and even more preferably 2% by mass or more, based on the total amount of the oil-in-water type topical composition. (E) The total content of component (E) is preferably 10% by mass or less, more preferably 8% by mass or less, even more preferably 6% by mass or less, and even more preferably 4% by mass or less, based on the total amount of the oil-in-water type topical composition, from the viewpoint of providing a good user experience.

[0033] <(F)(B) Polyglycerin fatty acid esters other than components> The oil-in-water type external composition according to this embodiment may contain, in addition to components (A), (B), and (C), a polyglycerin fatty acid ester other than component (B) as component (F). In this embodiment, component (F) may be used alone or in combination of two or more. It is not particularly limited as long as it is used in cosmetics, pharmaceuticals, or food products.

[0034] Examples of component (F) include polyglyceryl-10 stearate (HLB=14), polyglyceryl-10 isostearate (HLB=14), polyglyceryl-10 distearate (HLB=12), polyglyceryl-10 diisostearate (HLB=11), polyglyceryl-10 tristearate (HLB=10), polyglyceryl-10 triisostearate (HLB=10), polyglyceryl-10 pentaisostearate (HLB=5), and polyglyceryl-10 myristate (HLB=15). Component (F) is preferably a polyglyceryl fatty acid ester in which the fatty acid has a branched chain, and is particularly preferred if, for example, polyglyceryl-10 isostearate, polyglyceryl-10 diisostearate, polyglyceryl-10 triisostearate, or polyglyceryl-10 pentaisostearate. Polyglycerol fatty acid esters with such branched chains can result in flexible emulsion particles and impart high-temperature stability to the composition.

[0035] The total content of component (F) in the oil-in-water type topical composition according to this embodiment is not particularly limited and can be appropriately set depending on the type of water-soluble polysaccharide, the types of other components, etc. However, from the viewpoint of improving the stability of the composition, it is preferably 0.1% by mass or more, more preferably 0.5% by mass or more, even more preferably 1% by mass or more, even more preferably 1.5% by mass or more, even more preferably 2% by mass or more, and even more preferably 2.5% by mass or more, based on the total amount of the oil-in-water type topical composition. (F) The total content of component (F) is preferably 7% by mass or less, more preferably 5% by mass or less, even more preferably 4% by mass or less, and even more preferably 3% by mass or less, based on the total amount of the oil-in-water type topical composition, from the viewpoint of providing a good user experience.

[0036] The oil-in-water type topical composition according to this embodiment may further contain additional nonionic surfactants. However, it is preferable for the oil-in-water type topical composition of this embodiment to be substantially free of polyoxyethylene fatty acid esters or completely free of them in order to achieve even better stability. Here, substantially free means, for example, 2% by mass or less, preferably 1% by mass or less, more preferably 0.5% by mass or less, more preferably 0.1% by mass or less, and more preferably 0.01% by mass or less. When polyoxyethylene fatty acid esters are substantially free or absent, it is useful for maintaining the viscosity of the composition under high-temperature storage.

[0037] Polyoxyethylene fatty acid esters include polyoxyethylene fatty acid esters such as polyethylene glycol monostearate, polyethylene glycol stearate, and polyethylene glycol isostearate; and polyoxyethylene sorbitan fatty acid esters such as polyoxyethylene (20) sorbitan monolauryl acid (polysorbate 20), polyoxyethylene (20) sorbitan monostearate (polysorbate 60), polyoxyethylene (20) sorbitan monooleate (polysorbate 80), polyoxyethylene (20) sorbitan isostearate, polyoxyethylene sorbitan tristearate, and polyoxyethylene sorbitan oleate.

[0038] <Polar oil> The oil-in-water type external composition of this embodiment may contain a polar oil in addition to components (A), (B), and (C). In this embodiment, the polar oil may be used alone or in combination of two or more types. It is not particularly limited as long as it is used in cosmetics, pharmaceuticals, or food products.

[0039] From the viewpoint of achieving even more pronounced effects according to the present invention, it is also preferable to include ester oils among polar oils. Specifically, examples of ester oils include isostearyl isostearate, polyglyceryl triisostearate, caprylic / capric triglyceride, butylene glycol coconut oil fatty acid, tripropylene glycol dieopentanoate, isononyl isononanoate, isopropyl myristate, cetyl octanoate, octyldodecyl myristate, isopropyl palmitate, butyl stearate, hexyl laurate, myristyl myristate, decyl oleate, and dimethyloctanoic acid. Hexyldecyl, cetyl lactate, myristyl lactate, lanolin acetate, isocetyl stearate, isocetyl isostearate, cholesteryl 12-hydroxystearate, cetyl ethylhexanoate, ethylene glycol di-2-ethylhexanoate, dipentaerythritol fatty acid ester, N-alkyl glycol monoisostearate, neopentyl glycol dicaprate, diisostearyl malate, glyceryl di-2-heptylundecanoate, trimethylolpropane tri-2-ethylhexanoate Ingredients: Trimethylolpropane triisostearate, pentaerythrityl tetra-2-ethylhexanoate, triethylhexanoin (glycerin tri-2-ethylhexanoate), glycerin trioctanoate, glycerin triisopalmitate, trimethylolpropane triisostearate, cetyl 2-ethylhexanoate, 2-ethylhexyl palmitate, glycerin trimyristate, glyceride tri-2-heptyl undecanoate, methyl castor oil fatty acid ester, oleyl oleate, One or more substances selected from the group consisting of acetoglyceride, 2-heptyl undecyl palmitate, diisobutyl adipate, 2-octyldodecyl N-lauroyl-L-glutamate, di-2-heptyl undecyl adipate, ethyl laurate, di-2-ethylhexyl sebacate, 2-hexyldecyl myristate, 2-hexyldecyl palmitate, 2-hexyldecyl adipate, diisopropyl sebacate, 2-ethylhexyl succinate, and triethyl citrate.

[0040] The content of polar oil in the oil-in-water type topical composition according to this embodiment is not particularly limited and is set appropriately depending on the type of polar oil, the types and content of other compounding components, the use and formulation form of the oil-in-water type topical composition, etc. As for the content of polar oil, from the viewpoint of more significantly demonstrating the effects of the present invention, for example, based on the total amount of the oil-in-water type topical composition, the content of polar oil is preferably 0.0001% by mass or more, more preferably 0.0005% by mass or more, even more preferably 0.001% by mass or more, and even more preferably 0.005% by mass or more. Furthermore, the content of polar oil is preferably 50% by mass or less, more preferably 40% by mass or less, even more preferably 30% by mass or less, and even more preferably 20% by mass or less, based on the total amount of the oil-in-water type topical composition.

[0041] However, to achieve even better usability and safety, it is preferable that the oil-in-water type topical composition of this embodiment substantially or completely contains no ultraviolet absorbers. Here, substantially containing no ultraviolet absorbers means, for example, 1% by mass or less, preferably 0.1% by mass or less, and more preferably 0.01% by mass or less.

[0042] Examples of UV absorbers include one or more UV absorbers selected from the group consisting of benzoic acid derivatives, salicylic acid derivatives, cinnamic acid derivatives, dibenzoylmethane derivatives, β,β-diphenyl acrylate derivatives, benzophenone derivatives, benzylidene camphor derivatives, phenylbenzimidazole derivatives, triazine derivatives, phenylbenzotriazole derivatives, anthranyl derivatives, imidazoline derivatives, benzalmalonate derivatives, and 4,4-diarylbutadiene derivatives.

[0043] In particular, examples include one or more selected from the group consisting of 2-ethylhexyl paramethoxycinnamate, dimethicone diethylbenzalmalonate, octocrylene, diethylaminohydroxybenzoyl hexyl benzoate, paraaminobenzoic acid, 2,4-bis{[4-(2-ethylhexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine, 2,4,6-tris[4-(2-ethylhexyloxycarbonyl)anilino]-1,3,5-triazine, 4-tert-butyl-4'-methoxydibenzoylmethane, homomenthyl salicylate, ethylhexyl salicylate, octyl salicylate, oxybenzone, and dihydroxydimethoxybenzophenone.

[0044] In the oil-in-water type external composition according to this embodiment, the content ratio of (C) non-polar oil to 1 part by mass of polar oil is not particularly limited. However, from the viewpoint of more significantly exhibiting the effects of the present invention, for example, with respect to 1 part by mass of the total content of polar oil contained in the oil-in-water type external composition according to this embodiment, the total content of component (C) is preferably 0.1 to 20 parts by mass, 0.5 to 20 parts by mass, 0.7 to 20 parts by mass, 1 to 20 parts by mass, or 1 to 10 parts by mass.

[0045] The oil-in-water type external composition according to this embodiment preferably further contains an extender pigment. This makes the effects of the present invention more pronounced. The extender pigment may be used alone or in combination of two or more types. It is not particularly limited as long as it is used in cosmetics, pharmaceuticals, or food products. Commercially available extender pigments can be used. The extender pigment may be an extender pigment coated with titanium dioxide, iron oxide, silicone, etc. Among extender pigments, those that more significantly demonstrate the effects of the present invention include natural mica such as phlogopite and muscovite, synthetic mica, sericite, talc, kaolin, plate-like barium sulfate, magnesium carbonate, calcium carbonate, silicic acid, anhydrous silicic acid, magnesium silicate, magnesium oxide, and aluminum oxide. Of these, natural mica, synthetic mica, talc, and sericite are preferred, and mica, mica coated with titanium dioxide, and sericite are more preferred. When anhydrous silicic acid is included, it can be porous, non-porous, solid, or hollow, and the average particle size is preferably 1 to 20 μm, more preferably 2 to 15 μm, and even more preferably 2 to 10 μm. These can be appropriately selected from known materials and can be manufactured using conventional methods.

[0046] The content of the extender pigment in the oil-in-water type topical composition according to this embodiment is not particularly limited and is set appropriately depending on the type of extender pigment, the type and content of other compounding components, the use and formulation form of the oil-in-water type topical composition, etc. As for the content of the extender pigment, from the viewpoint of more significantly exhibiting the effects of the present invention, for example, it is preferably 0.1 to 8% by mass, more preferably 0.2 to 6.5% by mass, even more preferably 0.4 to 5% by mass, and particularly preferably 0.6 to 4% by mass, based on the total amount of the oil-in-water type topical composition.

[0047] The oil-in-water type topical composition according to this embodiment may contain one or more aqueous solvents, as long as they do not hinder the effects of the present invention. Water and polyhydric alcohols are preferred aqueous solvents. From the viewpoint of more significantly demonstrating the effects of the present invention, the aqueous solvent content is preferably 13 to 90% by mass, more preferably 20 to 80% by mass, even more preferably 28 to 70% by mass, and even more preferably 35 to 65% by mass, based on the total amount of the oil-in-water type topical composition. From the viewpoint of more significantly demonstrating the effects of the present invention, the water content is preferably 10 to 60% by mass, more preferably 15 to 55% by mass, even more preferably 20 to 50% by mass, and even more preferably 25 to 45% by mass, based on the total amount of the oil-in-water type topical composition. As for the polyhydric alcohol content, from the viewpoint of more significantly exhibiting the effects of the present invention, for example, it is preferably 1 to 30% by mass, more preferably 3 to 25% by mass, even more preferably 5 to 20% by mass, and even more preferably 8 to 20% by mass, based on the total amount of the oil-in-water type topical composition.

[0048] Examples of polyhydric alcohols include glycerin, diglycerin, dipropylene glycol, 1,3-propanediol, 1,3-butylene glycol, 1,2-propanediol, or 3-methyl-1,3-butanediol.

[0049] The oil-in-water type external composition according to this embodiment may contain known ingredients used in cosmetics, quasi-drugs, and pharmaceuticals, as long as they do not interfere with the effects of the present invention. In addition to the above ingredients (A) to (C), for example, antioxidants, functional brightening ingredients, moisturizers, anti-inflammatory ingredients, antibacterial agents, repellent ingredients, vitamins, amino acids, biological extracts, and various pharmacologically and physiologically active ingredients may be included in appropriate amounts in combination. Furthermore, one or more additives, preservatives, pH adjusters, chelating agents, stabilizers, buffering agents, lipophilic thickeners, gelling agents, irritation reducers, antiseptics, pearlescent agents, colorants, fragrances, minerals, etc., may be added individually or in combination. It is also possible to have a preservative-free formulation.

[0050] The oil-in-water type topical composition according to this embodiment preferably further contains a polymer obtained by polymerization of monomers containing sodium acryloyldimethyltaurate and / or ammonium acryloyldimethyltaurate. The polymer obtained by polymerization of monomers containing sodium acryloyldimethyltaurate and / or ammonium acryloyldimethyltaurate may be a homopolymer of these acryloyldimethyltaurate salt monomers, or a copolymer with one or more other monomers. Polymers obtained by polymerization of monomers containing sodium acryloyldimethyltaurate and / or ammonium acryloyldimethyltaurate include, for example, (hydroxyethyl acrylate / sodium acryloyldimethyltaurate) copolymer, (ammonium acryloyldimethyltaurate / vinylpyrrolidone) copolymer, (ammonium acryloyldimethyltaurate / beheneth-25 methacrylate) crosspolymer, (ammonium acryloyldimethyltaurate / steareth-25 methacrylate) crosspolymer, and (acrylic acid / acryloyldimethyltaurate / dimethylacrylamide) crosspolymer, of which (ammonium acryloyldimethyltaurate / vinylpyrrolidone) copolymer is preferred.

[0051] (viscosity) The viscosity (at 25°C) of the oil-in-water type external composition of this embodiment is not particularly limited as long as it is within the range of 1 to 500,000 mPa·s, but from the viewpoint of significantly demonstrating the effects of the present invention, it is preferably 100 to 500,000 mPa·s, more preferably 100 to 300,000 mPa·s, and even more preferably 1,000 to 200,000 mPa·s.

[0052] In this invention, viscosity measurement is performed using a single-cylinder rotational viscometer (Brookfield type viscometer) in accordance with the viscosity measurement method described in the general test methods of the 17th edition of the Japanese Pharmacopoeia. In this application, the TV-10M (Toki Sangyo) is used, and the selection of conditions such as rotor and rotation speed is in accordance with the instruction manual of this instrument, and viscosity is measured at 25°C. A description of the single-cylinder rotational viscometer is given below. A single-cylinder rotational viscometer is a viscometer that measures the torque when a cylinder in a liquid is rotated at a constant angular velocity. The viscosity η of the liquid is calculated by the following formula by experimentally determining the instrument constant KB in advance using a viscometer calibration standard solution. η = KB × T / ω η: Viscosity of liquid (mPa·s) KB: Equipment constant (rad / cm3) ω: Angular velocity (rad / s) T: Torque acting on a cylindrical surface (10⁻⁷ N·m)

[0053] (pH) The oil-in-water type topical composition of this embodiment may normally have a pH of 2.0 to 9.0, but from the viewpoint of low irritation to the skin and mucous membranes and good skin feel, it is preferably pH 3.0 to 8.5, more preferably pH 4.0 to 8.0, even more preferably pH 4.5 to 8.0, and even more preferably pH 5.0 to 8.0.

[0054] The oil-in-water type external composition according to this embodiment can be prepared by mixing and stirring each component according to a conventional method. The fact that it is an oil-in-water type composition can be confirmed by known methods. Although not limited to this, it can be confirmed by adding the composition to water and observing how it dissolves (is compatible with water).

[0055] The oil-in-water type topical composition according to this embodiment is not particularly limited in its drug form and can take any form known as a cosmetic, quasi-drug, or pharmaceutical. Among such known forms, examples include liquids, suspensions, emulsions, creams, gels, liniments, lotions, aerosols, poultices, sheets impregnated with the drug solution, and sticks such as lipsticks. Among these, liquids, suspensions, emulsions, creams, gels, and lotions are preferred in terms of their pleasant feel. It can also be used in the form of basic cosmetics such as emulsions, creams, body lotions, body creams, and sunscreens, as well as makeup cosmetics such as foundations, lipsticks, blushes, eye makeup, manicures, and pedicures, and functional topical agents such as insect repellents, anti-pollution topical agents, and hair growth agents. Preferably, it is a sunscreen cosmetic and can also be used as a makeup base. Although not limited, it can also be preferably used in products labeled as non-chemical formulations.

[0056] The oil-in-water type external composition according to this embodiment can be filled into a container appropriately selected according to the purpose and application of use and used. Examples of such containers include bottles, tubes, jars, sprays, aerosols, dispensers, pump-formers, pouches, and spout pouches. Examples of materials constituting the container include plastics (polyethylene terephthalate, polypropylene, polyethylene (HDPE, LDPE, LLDPE, etc.), ABS resin, ethylene vinyl alcohol resin, polystyrene, etc.), glass, and metals (aluminum, etc.), and mixtures thereof. Furthermore, containers molded from these materials may be subjected to various coating treatments on the surface of the container, taking into consideration strength, flexibility, weather resistance, or stability of the components. In addition, containers can be formed by laminating films or the like molded from the aforementioned materials.

[0057] The application area of ​​the oil-in-water type topical composition according to this embodiment is not particularly limited, but it can be applied to any of the following: face, arms, hands, feet, neck, scalp, hair, etc.

[0058] [2. Suppression of squeaky feeling in oil-in-water type topical compositions] In the oil-in-water type topical composition according to this embodiment, the squeaky feeling at the application site is suppressed by coexisting (A) 8% by mass or more of an ultraviolet scattering agent, (B) a polyglycerin fatty acid ester having at least one hydroxyl group in the fatty acid, and (C) a non-polar oil. Accordingly, one embodiment of the present invention provides a method for suppressing the squeaky feeling of the oil-in-water type topical composition by coexisting (A) 8% by mass or more of an ultraviolet scattering agent, (B) a polyglycerin fatty acid ester having at least one hydroxyl group in the fatty acid, and (C) a non-polar oil.

[0059] The types and content of component (A), component (B), component (C), other components, formulation form and use of the oil-in-water type topical composition in this embodiment are as described in [1. Oil-in-Water Type Topical Composition].

[0060] [3. Suppression of dryness in oil-in-water topical compositions] In the oil-in-water type topical composition according to this embodiment, the feeling of dryness at the application site is suppressed by coexisting (A) 8% by mass or more of an ultraviolet scattering agent, (B) a polyglycerin fatty acid ester having at least one hydroxyl group in the fatty acid, and (C) a non-polar oil. Accordingly, one embodiment of the present invention provides a method for suppressing the feeling of dryness in the oil-in-water type topical composition by coexisting (A) 8% by mass or more of an ultraviolet scattering agent, (B) a polyglycerin fatty acid ester having at least one hydroxyl group in the fatty acid, and (C) a non-polar oil.

[0061] The types and content of component (A), component (B), component (C), other components, formulation form and use of the oil-in-water type topical composition in this embodiment are as described in [1. Oil-in-Water Type Topical Composition].

[0062] [4. Suppression of residue formation in oil-in-water type topical compositions] In the oil-in-water type topical composition according to this embodiment, the formation of crumbly residue due to friction with the application site during application is suppressed by coexisting (A) 8% by mass or more of an ultraviolet scattering agent, (B) a polyglycerin fatty acid ester having at least one hydroxyl group in the fatty acid, and (C) a non-polar oil. Accordingly, one embodiment of the present invention provides a method for suppressing the formation of residue during application of the oil-in-water type topical composition by coexisting (A) 8% by mass or more of an ultraviolet scattering agent, (B) a polyglycerin fatty acid ester having at least one hydroxyl group in the fatty acid, and (C) a non-polar oil.

[0063] The types and content of component (A), component (B), component (C), other components, formulation form and use of the oil-in-water type topical composition in this embodiment are as described in [1. Oil-in-Water Type Topical Composition]. [Examples]

[0064] The present invention will be described in detail below based on test examples, but the present invention is not limited to these. Furthermore, the amounts used in the following examples are expressed in mass percent.

[0065] [Test Example 1] Oil-in-water topical compositions having the compositions shown in Tables 1-3 below were prepared according to conventional methods, and 50 g was placed in a polyethylene bottle. Five expert panelists applied the oil-in-water topical compositions to their faces and evaluated the feeling of tightness, dryness after 6 hours, and the generation of residue (clumps) during use according to evaluation criteria. The evaluation results are also shown in the table below.

[0066] (Evaluation of squeaking sensation) 0.5g of the composition was applied to the face, and after 3 minutes, the applied area was touched to evaluate the skin's texture. "Evaluation Criteria" The five expert panel members conducted individual evaluations and provided responses categorized as follows. ○ No squeaking sensation. △ I feel a slight creaking sensation. × I feel a strong creaking sensation.

[0067] The table shows the individual evaluations of the five expert panel members, categorized as follows: If all 5 people say yes, then it's A. If 3-4 out of 5 people give a "○" and the rest give a "△", then it's a "B". If only one person gives an "X," the rating will be C regardless of the other four people's ratings. If two or more people give an "X," the rating will be D regardless of the other people's evaluations.

[0068] (Evaluation of dryness) 0.5g of the composition was applied to the face, and the skin's texture was evaluated by touching the application area after 6 hours. "Evaluation Criteria" The five expert panel members conducted individual evaluations and provided responses categorized as follows. ○ Does not feel dry △ I feel a slight dryness. × I feel very dry.

[0069] The table shows the individual evaluations of the five expert panel members, categorized as follows: If all 5 people say yes, then it's A. If 3-4 out of 5 people give a "○" and the rest give a "△", then it's a "B". If only one person gives an "X," the rating will be C regardless of the other four people's ratings. If two or more people give an "X," the rating will be D regardless of the other people's evaluations.

[0070] (A worthless rating) 0.5g of the composition was applied to the face, and the condition during application was evaluated. "Evaluation Criteria" The five expert panel members conducted individual evaluations and provided responses categorized as follows. ○ Does not produce any crumbly residue. △ It leaves a small amount of crumbly residue, but it blends well into the skin. × Produces a lot of crumbly residue.

[0071] The table shows the individual evaluations of the five expert panel members, categorized as follows: If all 5 people say yes, then it's A. If 3-4 out of 5 people give a "○" and the rest give a "△", then it's a "B". If only one person gives an "X," the rating will be C regardless of the other four people's ratings. If two or more people give an "X," the rating will be D regardless of the other people's evaluations.

[0072] [Test Example 2] Oil-in-water topical compositions having the compositions shown in Tables 1-3 below were prepared according to conventional methods, and 50 g was placed in a glass screw-top bottle and the screw-top cap was closed. After standing at 50°C for 2 weeks (50°C treatment) or at 25°C for 2 weeks (25°C treatment), the samples were left to stand at 25°C for 18 hours. The stability of the oil-in-water topical compositions during high-temperature storage was evaluated by comparing the appearance and properties of the oil-in-water topical compositions treated at 50°C with those treated at 25°C. A: No change in appearance or properties. B: There may be slight separation or other changes in appearance and properties, requiring long-term monitoring. C: Changes in appearance or properties, such as aggregation or separation, impairing the product's value.

[0073] [Test Example 3] Oil-in-water topical compositions having the compositions shown in Tables 1 and 2 below were prepared according to conventional methods, and 50 g was placed in a glass screw-top bottle and the screw-top cap was closed. After standing at 25°C for 2 weeks (25°C treatment), the viscosity of the oil-in-water topical composition was measured. Furthermore, after standing at 40°C for 1 day, the viscosity was measured immediately after removal, and the change from the viscosity of the oil-in-water topical composition treated at 25°C was evaluated. A: No change in viscosity B: The viscosity decreases slightly, but there is no change in feel or usability. C: Viscosity decreases, resulting in a different feel and problematic usability. D: Viscosity decreases significantly.

[0074] [Table 1] [Table 2] [Table 3]

[0075] As shown in the table, in the reference example where the amount of component (A) was 6% by mass, it was found that squeaky feeling, dryness, and residue formation were less likely to occur, and stability problems were also less likely to occur. However, with an amount of around 6% by mass, it is not possible to achieve a high SPF, and it is difficult to exert sufficient UV protection. In the oil-in-water type topical composition of the example, despite the amount of component (A) being 8% by mass or more, squeaky feeling and dryness were suppressed, and furthermore, the effect of suppressing residue formation was excellent.

[0076] Furthermore, among the oil-in-water type external compositions of the examples, the compositions of Examples 1 to 5 were found to be very stable, showing little change in appearance or properties after high-temperature storage, as well as little change in viscosity.

[0077] Tables 4-7 below show examples of formulations. [Table 4] [Table 5] [Table 6] [Table 7]

Claims

1. An oil-in-water external composition containing (A) 8% by mass or more of an ultraviolet scattering agent, (B) a polyglycerin fatty acid ester having at least one hydroxyl group in the fatty acid, and (C) a nonpolar oil.

2. Furthermore, the oil-in-water type external composition according to claim 1, further comprising (D) a water-soluble polysaccharide.

3. Furthermore, the oil-in-water type external composition according to claim 1 or 2, further comprising (E) a higher alcohol having 14 to 20 carbon atoms.

4. The oil-in-water type topical composition according to claim 1 or 2, wherein the (A) ultraviolet scattering agent is hydrophobized with an alkoxysilane.

5. The oil-in-water external composition according to claim 1 or 2, wherein component (A) and component (B) are dispersed in an oil phase.

6. The topical skin composition according to claim 1 or 2, wherein the ratio of the total content of component (B) to component (A) is 0.005 to 1 part by mass.

7. A topical skin composition according to claim 1 or 2, which substantially does not contain an ultraviolet light absorbing agent.

8. The oil-in-water type external composition according to claim 1 or 2, further comprising polyglycerin fatty acid esters other than (F) and (B).

9. The oil-in-water type topical composition according to claim 8, wherein the fatty acid of component (F) has a branched chain.

10. An oil-in-water topical composition according to claim 1 or 2, which is substantially free of polyoxyethylene fatty acid esters.

11. A method for suppressing a squeaky feeling, dryness, or the formation of residue due to friction with the skin when applied, by coexisting (A) an ultraviolet scattering agent in an amount of 8% by mass or more, (B) a polyglycerin fatty acid ester having at least one hydroxyl group in the fatty acid, and (C) a nonpolar oil in an oil-in-water type topical composition.

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