Catheter device

Abstract

This invention provides a catheter device that can be used for minimally invasive treatment that can suppress the re-inflow of blood into the aneurysm. [Solution] The catheter device according to the present disclosure comprises a long member that partitions a first lumen and a second lumen, a hooking portion that can be hooked onto biological tissue, a hooking member that can be inserted into the first lumen, and an optical transmission member that can be inserted into the second lumen, wherein the long member has a recess on its tip surface, and on the inner surface of the recess a first tip opening connected to the first lumen and a second tip opening connected to the second lumen are formed, the hooking member is capable of drawing the biological tissue hooked by the hooking portion into the recess, and the optical transmission member is capable of irradiating the biological tissue drawn into the recess by the hooking member with the laser through the second tip opening.

Description

[[TECHNICAL FIELD]]

[0001] The present disclosure relates to a catheter device. [[BACKGROUND ART]]

[0002] Conventionally, invasive treatments such as craniotomy for cerebral aneurysms have been known as methods for treating aneurysms. As one such invasive treatment, craniotomy clipping is known, in which the neck of a cerebral aneurysm is clipped with a clip to block blood flow into the dome of the cerebral aneurysm. In addition, minimally invasive treatment for treating an aneurysm from within the blood vessel is also known as a method for treating an aneurysm. Examples of such minimally invasive treatments include coil embolization and WEB (abbreviation for Woven EndoBridge) implantation. Patent Document 1 describes an implant delivery device that can be used for delivering an implant such as a coil into an aneurysm. [[PRIOR ART DOCUMENT]] [[PATENT DOCUMENT]]

[0003] [[Patent Document 1]] Japanese National Publication of International Patent Application No. 2008-510594 [[SUMMARY OF THE INVENTION]] [[Problem to be Solved by the Invention]]

[0004] The aforementioned coil embolization and WEB implantation impose a small physical burden on patients. On the other hand, the aforementioned coil embolization and WEB implantation still have a problem in that re-inflow of blood into the aneurysm may occur.

[0005] An object of the present disclosure is to provide a catheter device that can be used in minimally invasive treatment capable of suppressing re-inflow of blood into an aneurysm. [[Means for Solving the Problem]]

[0006] The catheter device according to a first aspect of the present disclosure is (1) A long member that separates the first lumen and the second lumen, A hooking member is provided at the tip, which can hook onto biological tissue, and which can be inserted into the first lumen. The device comprises a laser emission section at its tip capable of emitting a laser, and an optical transmission member that can be inserted into the second lumen, The aforementioned elongated member has a recess on its tip surface, On the inner surface of the recess, A first tip opening connected to the first lumen, A second tip opening connected to the second lumen is formed, The hooking member is such that its tip protrudes from the elongated member through the first tip opening, allowing the hooking portion to hook onto the biological tissue, and the biological tissue hooked by the hooking portion can be drawn into the recess when the tip is pulled back toward the first tip opening. The laser emission portion of the optical transmission member is a catheter device that can irradiate the biological tissue, which is drawn into the recess by the hooking member, with the laser through the second tip opening.

[0007] A catheter device as one embodiment of the present disclosure is (2) The aforementioned recess is The bottom part, Edge and, It comprises a tapered side portion that decreases in diameter from the edge portion toward the bottom portion, The first tip opening is formed in the bottom surface portion of the recess, The second tip opening is formed in the tapered side portion of the recess, and is the catheter device described in (1) above.

[0008] A catheter device as one embodiment of the present disclosure is (3) The tip of the hooking member is deformable toward the radially outward direction of the elongated member by protruding from the first tip opening, as described in (1) or (2) above, and is a catheter device according to (1) or (2).

[0009] A catheter device as one embodiment of the present disclosure is (4) The tip of the hooking member is housed in the first lumen in an elastically deformed state and protrudes from the first tip opening, thereby being deformable radially outward by a restoring force, as described in (3) above.

[0010] A catheter device as one embodiment of the present disclosure is (5) The aforementioned hooking member comprises multiple wires, The tip of the hooking member includes the multiple free ends of the multiple wires, The catheter device is as described in (3) or (4) above, wherein the plurality of free ends of the plurality of wires protrude from the first tip opening and are deformable radially outward.

[0011] A catheter device as one embodiment of the present disclosure is (6) Each of the aforementioned multiple wires has a fan-shaped cross-section, The plurality of wires are housed in the first lumen so as to form a circular cross-sectional shape, and the catheter device is as described in (5) above.

[0012] A catheter device as one embodiment of the present disclosure is (7) The aforementioned elongated member is The tip portion including the aforementioned tip surface, Located on the base end side of the aforementioned tip, the main body portion has a larger diameter than the aforementioned tip, The device comprises a connecting portion that connects the tip portion and the main body portion, and whose outer diameter decreases from the main body portion side toward the tip portion side, The main body portion of the elongated member defines a third lumen radially outward of the elongated member from the second lumen, into which an optical transmission member different from said optical transmission member can be inserted, The catheter device according to any one of the above (1) to (6), wherein a third distal opening communicating with the third lumen is formed on an outer surface of the connecting portion. Effects of the Invention

[0013] According to the present disclosure, a catheter device that can be used for minimally invasive treatment capable of suppressing re-inflow of blood into an aneurysm can be provided. Brief Description of the Drawings

[0014] [Figure 1] It is a figure showing a catheter device as one embodiment of the present disclosure. [Figure 2] It is a perspective view of the distal end portion of the catheter device shown in FIG. 1. [Figure 3] It is a view of the distal end portion of the catheter device shown in FIG. 2 as viewed from the distal end side. [Figure 4] It is a cross-sectional view of the distal end portion of the catheter device shown in FIG. 2, showing a state before a hooking member is deployed. [Figure 5] It is a figure showing a state where the hooking member is deployed from the state shown in FIG. 4. [Figure 6A] It is a figure showing a state where the catheter device shown in FIG. 1 is inserted to the position of a saccular aneurysm in an artery. [Figure 6B] It is a figure showing a state where the distal end portion of the hooking member including a hooking portion is projected from the distal end surface of the elongated member through the first distal opening from the state of FIG. 6A. [Figure 6C] It is a figure showing a state where the hooking portion at the distal end of the hooking member is hooked on the swollen portion of the artery from the inside of the dome of the saccular aneurysm. [Figure 6D]This figure shows the state in which the tip of the hooking member is pulled back towards the first tip opening, and the laser is irradiated onto the biological tissue that has been pulled into the recess by the optical transmission member, starting from the state shown in Figure 6C. [Figure 6E] This figure shows the state after laser ablation is completed in the condition shown in Figure 6D, and the hooking member and optical transmission member have been removed from the body through the first and second lumens. [Figure 6F] This figure shows the state after the long member has been removed from the body, completing the treatment, as shown in Figure 6E. [Figure 7] This diagram shows a modified example of the hooking mechanism, illustrating a state in which multiple free ends of multiple wires are housed in the first lumen. [Figure 8] Figure 7 shows a modified example of a hooking mechanism, illustrating a state where multiple free ends of multiple wires are not housed in the first lumen. [Figure 9A] This is a perspective view showing the tip of a catheter device as one embodiment of the present disclosure. [Figure 9B] Figure 9A shows the tip of the catheter device as viewed from the tip side. [Modes for carrying out the invention]

[0015] Hereinafter, embodiments of the catheter device relating to this disclosure will be described with reference to the drawings. In each figure, identical components are denoted by the same reference numerals.

[0016] Figure 1 shows a catheter device 100 as one embodiment of the catheter device according to the present disclosure. In Figure 1, a laser oscillator 500 is also shown in addition to the catheter device 100. Figure 2 is a perspective view of the tip of the catheter device 100. Figure 3 is a view of the tip of the catheter device 100 from the tip side. Figure 4 is a cross-sectional view of the tip of the catheter device 100. Figure 4 shows the state before the hooking member 30 is deployed. Figure 5 shows the state after the hooking member 30 has been deployed from the state shown in Figure 4. Note that in Figures 4 and 5, for the sake of explanation, the hooking member 30 and the optical transmission member 50 are shown in side views.

[0017] The catheter device 100 can be used, for example, to treat aneurysms such as arterial aneurysms. However, the use of the catheter device 100 is not particularly limited. The catheter device 100 may be used not only for the treatment of aneurysms but also for the treatment of other lesions in the biological tissue of blood vessels.

[0018] As shown in Figures 1 to 5, the catheter device 100 comprises a long member 10, a hooking member 30, and an optical transmission member 50.

[0019] As shown in Figures 4 and 5, the elongated member 10 divides the first lumen 11 and the second lumen 12. The elongated member 10 can be inserted into blood vessels or other vascular structures.

[0020] As shown in Figures 4 and 5, the hooking member 30 can be inserted into the first lumen 11 of the long member 10. Also, as shown in Figures 4 and 5, the hooking member 30 has a hooking portion 31a at its tip 31 that can hook onto biological tissue. As will be described in detail later, in this embodiment, the tip 31 of the hooking member 30 is composed of multiple free ends 41 of multiple wires 40. The tip of the free end 41 of each wire 40 is formed in a hook shape. The hooking portion 31a in this embodiment is composed of an aggregate of the hook-shaped tip portions of the free ends 41 of the wires 40.

[0021] As shown in Figures 4 and 5, the optical transmission member 50 can be inserted into the second lumen 12 of the elongated member 10. The optical transmission member 50 is equipped with a laser emission section 51 at its tip that can emit a laser.

[0022] As shown in Figures 2 to 5, the elongated member 10 has a recess 13 on its tip surface 10a. A first tip opening 11a, which is connected to the first lumen 11, is formed on the inner surface of the recess 13. A second tip opening 12a, which is connected to the second lumen 12, is also formed on the inner surface of the recess 13.

[0023] As shown in Figure 5, the hooking member 30 can hook onto biological tissue by extending its tip portion 31, including the hooking portion 31a, through the first tip opening 11a from the long member 10. Details of this will be described later (see Figure 6C). Furthermore, the hooking member 30 can pull the biological tissue hooked by the hooking portion 31a into the recess 13 by pulling the tip portion 31, including the hooking portion 31a, back toward the first tip opening 11a. Details of this will also be described later (see Figure 6D).

[0024] The laser emission section 51 of the optical transmission member 50 can irradiate the biological tissue, which is drawn into the recess 13 by the hooking member 30, with a laser through the second tip opening 12a. Details of this will be described later (see Figure 6D).

[0025] Thus, with the catheter device 100, biological tissue from a vascular lesion, such as an aneurysm, can be drawn into the recess 13 using the hooking member 30. Furthermore, with the catheter device 100, the laser emission unit 51 of the optical transmission member 50 can irradiate the biological tissue of the lesion drawn into the recess 13 with a laser through the second tip opening 12a. This makes it possible to reliably perform treatments that involve irradiating the biological tissue of a lesion with a laser, such as laser ablation of the biological tissue of the lesion.

[0026] Therefore, in the treatment of aneurysms and other aneurysms using the catheter device 100, the bulging portion of the blood vessel can be pulled into the recess 13 from inside the blood vessel using the hooking member 30, and can also be cauterized using the optical transmission member 50. In other words, the catheter device 100 can reduce the size of the aneurysm or eliminate it altogether. Thus, by using the catheter device 100, it is possible to perform minimally invasive treatment that can suppress the re-inflow of blood into the aneurysm. Further details will be described later (see Figures 6A to 6F).

[0027] Next, further details of the catheter device 100 of this embodiment will be described.

[0028] In this embodiment, the longitudinal direction of the long member 10 of the catheter device 100 is described as "longitudinal direction A of the long member 10" or simply "longitudinal direction A". Furthermore, in longitudinal direction A, the direction from the proximal end to the proximal end of the catheter device 100 is simply described as "distal A1", and the direction from the proximal end to the proximal end of the catheter device 100 is simply described as "proximal A2". In addition, the circumferential direction of the long member 10 of the catheter device 100 is described as "circumferential direction B of the long member 10" or simply "circumferential direction B". Furthermore, in the catheter device 100, the radial direction of the long member 10 in a cross section perpendicular to the longitudinal direction A of the long member 10 is described as "radial direction C of the long member 10" or simply "radial direction C".

[0029] As shown in Figure 1, the elongated member 10 of this embodiment comprises a tubular body 20 and a hub 21. The first lumen 11 and the second lumen 12 of this embodiment are formed across the tubular body 20 and the hub 21.

[0030] The tubular body 20 of this embodiment has a peripheral wall that partitions the first lumen 11 on its inside. The second lumen 12 of this embodiment is formed within the wall of the peripheral wall of the tubular body 20. Furthermore, as shown in Figures 2 to 5, the elongated member 10 of this embodiment partitions a plurality (six in this embodiment) of second lumens 12. The plurality of second lumens 12 of this embodiment are arranged within the wall of the peripheral wall of the tubular body 20 at intervals in the circumferential direction B.

[0031] In this embodiment, the first lumen 11 and the second lumen 12 extend along the central axis O. Furthermore, the first lumen 11 in this embodiment is located at a position that includes the central axis O of the tubular body 20. In contrast, the second lumen 12 in this embodiment is located at a position that does not include the central axis O of the tubular body 20.

[0032] As shown in Figures 2 to 5, the elongated member 10 in this embodiment partitions only one first lumen 11, but the number of first lumens 11 partitioned by the elongated member 10 is not particularly limited. The elongated member 10 may partition, for example, multiple first lumens 11.

[0033] Furthermore, as shown in Figures 2 to 5, the elongated member 10 of this embodiment partitions multiple (six in this embodiment) second lumens 12, but the number of second lumens 12 partitioned by the elongated member 10 is not particularly limited. The elongated member 10 may, for example, partition only one second lumen 12. However, from the viewpoint of improving treatment efficiency, it is preferable that the elongated member 10 partitions multiple second lumens 12. In this way, lasers can be irradiated from multiple light transmission members 50 to the biological tissue drawn into the recess 13. This improves treatment efficiency.

[0034] The tip surface 10a of the elongated member 10 in this embodiment is the tip surface of the tubular body 20. In other words, the recess 13 in this embodiment is formed on the tip surface of the tubular body 20.

[0035] As shown in Figures 4 and 5, the recess 13 of this embodiment comprises a bottom surface portion 13a, an edge portion 13b, and a tapered side portion 13c. The tapered side portion 13c decreases in diameter from the edge portion 13b toward the bottom surface portion 13a. More specifically, the tapered side portion 13c of this embodiment extends inclined with respect to the longitudinal direction A from the edge portion 13b toward the bottom surface portion 13a, such that its diameter gradually decreases toward the proximal side A2 of the longitudinal direction A. In other words, the tapered side portion 13c of this embodiment is the inclined tip surface of the peripheral wall of the tubular body 20. The tip surface of the peripheral wall of the tubular body 20 is inclined with respect to the longitudinal direction A such that its inner edge is located proximal side A2 of the longitudinal direction A compared to its outer edge.

[0036] As shown in Figures 4 and 5, the first tip opening 11a in this embodiment is formed on the bottom surface 13a of the recess 13. More specifically, the first tip opening 11a in this embodiment is formed over the entire bottom surface 13a of the recess 13. However, the first tip opening 11a may be formed only on a part of the bottom surface 13a of the recess 13.

[0037] Furthermore, as shown in Figures 4 and 5, the second tip opening 12a of this embodiment is formed on the tapered side surface portion 13c of the recess 13. More specifically, the multiple (six in this embodiment) second tip openings 12a of this embodiment are formed on the tapered side surface portion 13c of the recess 13 at intervals in the circumferential direction B.

[0038] The base end of the tubular body 20 is fixed to the hub 21. As shown in Figure 1, the hub 21 has a first insertion opening 21a into which the hooking member 30 can be inserted into the first lumen 11. The hub 21 also has a second insertion opening 21b into which the optical transmission member 50 can be inserted into the second lumen 12. As described above, the elongated member 10 of this embodiment divides six second lumens 12. A separate optical transmission member 50 is inserted into each of the six second lumens 12. Therefore, the hub 21 of this embodiment has six second insertion openings 21b. However, for the sake of explanation, only one second insertion opening 21b is shown in Figure 1.

[0039] Furthermore, as shown in Figure 1, the hub 21 of this embodiment includes a hub body portion 21c to which the base end of the tubular body 20 is fixed. The tips of the first insertion portion 21a and the second insertion portion 21b are fixed to the hub body portion 21c.

[0040] The tubular body 20 of the long member 10 is preferably formed from a flexible material, but the material is not particularly limited. Examples of constituent materials for the tubular body 20 include various thermoplastic elastomers such as styrene-based, polyolefin-based, polyurethane-based, polyester-based, polyamide-based, polyimide-based, polybutadiene-based, trans-polyisoprene-based, fluororubber-based, and chlorinated polyethylene-based materials. One or more of these materials combined (polymer alloys, polymer blends, laminates, etc.) can also be used. Furthermore, a hydrophilic lubricating coating layer that exhibits lubricity when wet may be placed on the outer surface of the tubular body 20.

[0041] The constituent material of the hub 21 of the long member 10 is not particularly limited, but examples include resin materials such as polyethylene, polypropylene, polyolefins such as ethylene-vinyl acetate copolymer, polyurethane, polyamide, polyester, polycarbonate, polybutadiene, polyvinyl chloride, and polyacetal.

[0042] As described above, the tip portion 31 of the hooking member 30 can protrude from the tip surface 10a of the elongated member 10 through the first tip opening 11a. As shown in Figures 4 and 5, the tip portion 31 of the hooking member 30 in this embodiment can deform outward in the radial direction C of the elongated member 10 by protruding from the first tip opening 11a. This makes it easier to hook the hooking portion 31a of the tip portion 31 of the hooking member 30 over a wide area of ​​biological tissue. Therefore, in the treatment of aneurysms using the catheter device 100 of this embodiment, the hooking portion 31a can be hooked over a wide area of ​​the bulging portion of the blood vessel. This makes it possible to pull a wide area of ​​the bulging portion of the blood vessel into the recess 13 (see Figure 6D).

[0043] Specifically, the tip portion 31 of the hooking member 30 in this embodiment is housed in the first lumen 11 in an elastically deformed state, and can be deformed outward in the radial direction C by the restoring force by protruding from the first tip opening 11a. In other words, as shown in Figure 4, the tip portion 31 of the hooking member 30 in this embodiment can be inserted into the first lumen 11 in an elastically deformed state toward the inward direction C. Then, as shown in Figure 5, the tip portion 31 of the hooking member 30 in this embodiment can be deformed outward in the radial direction C by the restoring force by protruding from the first tip opening 11a. In other words, the tip portion 31 of the hooking member 30 in this embodiment is shape-memorized to deform outward in the radial direction C by protruding from the first tip opening 11a.

[0044] More specifically, as shown in Figures 2 to 5, the hooking member 30 of this embodiment comprises a plurality of wires 40 (six in this embodiment) extending in the longitudinal direction A. As shown in Figures 4 and 5, the hooking member 30 comprises a main body portion 32 consisting of a binding portion to which the plurality of wires 40 are bound together, and a tip portion 31 connected to the tip side of the main body portion 32 and consisting of an unbound portion to which the plurality of wires 40 are not bound. The main body portion 32 may be bound together, for example, by joining the plurality of wires 40 by adhesive or the like. The tip portion 31 of the hooking member 30 of this embodiment includes a plurality of free ends 41 of the plurality of wires 40. More specifically, the tip portion 31 of the hooking member 30 of this embodiment is composed of a plurality of free ends 41 of the plurality of wires 40. And, as shown in Figure 5, the plurality of free ends 41 of the plurality of wires 40 can be deformed radially outward in the radial direction C by protruding from the first tip opening 11a.

[0045] The hook portion 31a of the hooking member 30 in this embodiment is composed of multiple tip portions of multiple free ends 41 of multiple wires 40. Specifically, the hook portion 31a in this embodiment is a barb formed on the multiple tip portions of multiple free ends 41 of multiple wires 40. The configuration of the barb as the hook portion 31a is not particularly limited, but as in this embodiment, it may be formed, for example, by making the tip portion of the free end 41 of each wire 40 hook-shaped. The hook-shaped tip portion at the free end 41 of each wire 40 may be shape-memorized, for example, so that it is hook-shaped when no external force is applied. In other words, the hook-shaped tip portion at the free end 41 of each wire 40 may extend in a straight line when inserted through the first lumen 11 of the long member 10, and may deform into a hook shape due to the restoring force when protruding from the first tip opening 11a.

[0046] As described above, the hook portion 31a in this embodiment is a barb formed on the multiple ends of the multiple free ends 41 of the multiple wires 40, but the hook portion 31a is not limited to this configuration. Figures 7 and 8 show a modified example of the hook portion 31a. The hook portion 31a shown in Figures 7 and 8 is a multiple claw portion 42. Each of the multiple claw portions 42 is attached to the end of the free end 41 of the wire 40. Figure 7 shows the state in which the multiple free ends 41 of the multiple wires 40 are housed in the first lumen 11. Figure 8 shows the state in which the multiple free ends 41 of the multiple wires 40 are not housed in the first lumen 11. In Figures 7 and 8, the position of the first lumen 11 is indicated by a dashed line. As shown in Figure 7, each of the multiple claw portions 42 is housed in the first lumen 11 such that its tip faces inward in the radial direction C. As shown in Figure 8, when multiple free ends 41 of multiple wires 40 protrude from the first tip opening 11a (see Figure 4, etc.), each of the multiple free ends 41 of the multiple wires 40 deforms outward in the radial direction C while twisting. As each of the multiple free ends 41 of the multiple wires 40 twists, the tips of each of the multiple claw portions 42 face outward in the radial direction C. This allows the tips of the claw portions 42 to hook onto biological tissue. Conversely, the twisting of each of the multiple free ends 41 of the multiple wires 40 is released when they are pulled back into the first lumen 11 from the state shown in Figure 8. As a result, each of the multiple claw portions 42 rotates so that its tip faces inward in the radial direction C. As a result, the biological tissue that the tips of each of the multiple claw portions 42 are hooked onto is twisted as the multiple claw portions 42 rotate and pulled into the recess 13 (see Figure 4, etc.).

[0047] Thus, the configuration of the hook portion 31a is not particularly limited, as long as it is capable of hooking onto biological tissue.

[0048] Furthermore, each of the multiple wires 40 shown in Figures 7 and 8 has a fan-shaped cross-section. As shown in Figure 7, the multiple wires 40 are housed in the first lumen 11 such that they form a circular cross-section as a whole. In this way, the overall cross-sectional area of ​​the multiple wires 40 housed in the first lumen 11 can be reduced. This makes it possible to make the first lumen 11 thinner, and the entire long member 10 can be made thinner. Note that the fan-shaped cross-section of the wires 40 shown in Figures 7 and 8 may also be applied to the cross-sectional shape of the wires 40 in Figures 1 to 5.

[0049] The hook member 30 shown in Figures 7 and 8 comprises eight wires 40. Therefore, by setting the central angle of the fan-shaped cross-section of each wire 40 to 45 degrees, the eight wires 40 as a whole form a circular cross-sectional shape, as shown in Figure 7. However, the number of wires 40 is not particularly limited. Therefore, the central angle of the fan-shaped cross-section of each wire 40 may be appropriately designed according to the number of wires 40.

[0050] Each of the multiple wires 40 of the hooking member 30 may be made of a shape memory alloy, for example, which is given shape memory effect or superelasticity by heat treatment. Examples of shape memory alloys include Ni-Ti, Cu-Al-Ni, and Cu-Zn-Al alloys.

[0051] The optical transmission member 50 is insertable into the second lumen 12 of the long member 10. The optical transmission member 50 has a laser emission section 51 at its tip that can emit a laser. More specifically, the optical transmission member 50 of this embodiment has a laser emission section 51 on its tip surface. As shown in Figure 1, the base end of the optical transmission member 50 is connectable to a laser oscillator 500. The laser emitted by the laser oscillator 500 passes through the optical transmission member 50 and is emitted from the laser emission section 51 on the tip surface of the optical transmission member 50. The optical transmission member 50 may be, for example, an optical fiber.

[0052] As shown in Figures 4 and 5, the optical transmission member 50 is inserted through the second lumen 12 of the elongated member 10 so that its tip surface is positioned at the second tip opening 12a. In this state, by emitting a laser from the laser emission section 51, the laser can be irradiated onto the biological tissue that has been pulled into the recess 13 by the hooking member 30.

[0053] As shown in Figure 3, the catheter device 100 of this embodiment includes a plurality (six in this embodiment) of optical transmission members 50. Each of the plurality of optical transmission members 50 is inserted into each of the six second lumens 12 of the elongated member 10. However, the number of optical transmission members 50 included in the catheter device 100 is not particularly limited. The catheter device 100 may be configured to include, for example, only one optical transmission member 50. However, as described above, from the viewpoint of improving the efficiency of treatment, it is preferable that the catheter device 100 includes a plurality of optical transmission members 50.

[0054] Next, an example of the use of the catheter device 100 of this embodiment will be described with reference to Figures 6A to 6F. Figures 6A to 6F are diagrams illustrating an example of the use of the catheter device 100. Specifically, Figures 6A to 6F show an example in which the catheter device 100 is used for the treatment of a saccular aneurysm X.

[0055] Figure 6A shows the catheter device 100 inserted into the arterial AT to the location of the saccular aneurysm X. As shown in Figure 6A, the catheter device 100 is positioned in the arterial AT such that the tip surface 10a of the elongated member 10 faces inward into the dome of the saccular aneurysm X from the neck of the saccular aneurysm X.

[0056] When the long member 10 is inserted into the arterial AT, the hooking member 30 may be housed in the first lumen 11, for example, without protruding from the first tip opening 11a. In other words, the hooking member 30 may be inserted into the arterial AT together with the long member 10. However, the hooking member 30 does not have to be housed in the first lumen 11 when the long member 10 is inserted into the arterial AT. In other words, the hooking member 30 may be inserted into the first lumen 11 of the long member 10 after the long member 10 has been inserted into the arterial AT.

[0057] When the elongated member 10 is inserted into the arterial AT, the optical transmission member 50 may be housed in the second lumen 12, for example, without protruding from the second tip opening 12a. In other words, the optical transmission member 50 may be inserted into the arterial AT together with the elongated member 10. However, the optical transmission member 50 does not have to be housed in the second lumen 12 when the elongated member 10 is inserted into the arterial AT. In other words, the optical transmission member 50 may be inserted into the second lumen 12 of the elongated member 10 after the elongated member 10 has been inserted into the arterial AT.

[0058] Figure 6B shows the state in which the tip portion 31 of the hooking member 30, including the hook portion 31a, protrudes from the tip surface 10a of the elongated member 10 through the first tip opening 11a, compared to the state in Figure 6A. As shown in Figure 6B, the hooking member 30 enters the dome of the saccular aneurysm X. In addition, in this embodiment, the free ends 41 of the multiple wires 40 constituting the tip portion 31 of the hooking member 30 deform so that they spread radially outward in the radial direction C.

[0059] Figure 6C shows that, from the state in Figure 6B, the tip 31 of the hooking member 30 has advanced further into the dome of the saccular aneurysm X, and the hooking portion 31a of the tip 31 has hooked onto the vascular wall of the bulging portion of arterial AT from inside the dome of the saccular aneurysm X. As described above, the hooking portion 31a in this embodiment is composed of multiple tips of multiple free ends 41 of multiple wires 40. In other words, Figure 6C shows that the multiple tips of multiple free ends 41 of multiple wires 40 have hooked onto the vascular wall of the saccularly bulging portion of arterial AT from inside the dome of the saccular aneurysm X.

[0060] Figure 6D shows the state in which, from the state shown in Figure 6C, the tip 31 of the hooking member 30 is pulled back toward the first tip opening 11a, and the optical transmission member 50 is irradiating the biological tissue that has been pulled into the recess 13 with a laser. More specifically, the multiple free ends 41 of the multiple wires 40 are pulled back toward the first tip opening 11a. This allows the vascular wall of the saccularly bulging portion of the artery AT, which is the biological tissue that is hooked by the hooking portion 31a, to be pulled into the recess 13, as shown in Figure 6D. In this state, the optical transmission member 50 irradiates the vascular wall of the bulging portion of the artery AT, which is the biological tissue that has been pulled into the recess 13 by the hooking member 30, with a laser through the second tip opening 12a. This allows the saccular vascular wall that forms the dome of the saccular aneurysm X to be ablated by the laser within the recess 13.

[0061] Figure 6E shows the state after laser ablation is completed in the state shown in Figure 6D, and the hooking member 30 and the optical transmission member 50 have been removed from the body through the first lumen 11 and the second lumen 12. Figure 6F shows the state after the long member 10 has been removed from the body from the state shown in Figure 6E, and the treatment is complete. In this way, the catheter device 100 can reliably laser ablate the saccular blood vessel wall of the saccular aneurysm X within the recess 13.

[0062] Furthermore, as described above, the first tip opening 11a in this embodiment is formed on the bottom surface 13a (see Figure 4) of the recess 13. Therefore, compared to a configuration in which the first tip opening 11a is formed on the tapered side surface 13c (see Figure 4), biological tissue hooked onto the hooking portion 31a of the tip 31 of the hooking member 30 is more easily drawn into the recess 13.

[0063] Furthermore, as described above, the second tip opening 12a of this embodiment is formed on the tapered side portion 13c (see Figure 4) of the recess 13. Because the second tip opening 12a is formed on the inner surface of the recess 13, it is possible to suppress the irradiation of biological tissue that is not drawn into the recess 13 and is not the target of laser irradiation. In other words, the target of the laser irradiation emitted from the laser emission portion 51 of the optical transmission member 50 can be concentrated on the biological tissue drawn into the recess 13. This makes it possible to increase the efficiency of laser irradiation to the biological tissue drawn into the recess 13 and shorten the laser irradiation time required to complete the treatment.

[0064] Furthermore, since the second tip opening 12a is formed on the tapered side portion 13c (see Figure 4) of the inner surface of the recess 13, it is possible to suppress the emission of the laser from the laser emission portion 51 of the optical transmission member 50 toward the distal side A1 along the longitudinal direction A. This further suppresses the irradiation of biological tissue that is not drawn into the recess 13 and is not the target of laser irradiation. Specifically, as shown in Figures 4 and 5, the second lumen 12 of this embodiment includes a curved portion 12b that extends inclined with respect to the longitudinal direction A in the vicinity of the second tip opening 12a. As shown in Figures 4 and 5, the curved portion 12b extends inclined so as it approaches the central axis O toward the distal side A1 in the longitudinal direction A. As a result, the optical transmission member 50 inserted into the second lumen 12 is positioned such that, at the location of the second tip opening 12a, the tip surface on which the laser emission portion 51 is provided faces in a direction inclined with respect to the longitudinal direction A. More specifically, the optical transmission member 50 is positioned such that, at the position of the second tip aperture 12a, the tip surface on which the laser emission unit 51 is provided faces inward in the radial direction C. In other words, among the inner surfaces that define the second lumen 12, a guide surface 12c is formed near the second tip aperture 12a to guide the tip surface of the optical transmission member 50 on which the laser emission unit 51 is provided to face in a direction inclined with respect to the longitudinal direction A. This suppresses the emission of laser from the laser emission unit 51 of the optical transmission member 50 toward the distal side A1 along the longitudinal direction A. In particular, in this embodiment, each optical transmission member 50 is positioned such that, at the position of the second tip aperture 12a, the tip surface on which the laser emission unit 51 is provided faces inward in the radial direction C, so that the lasers from the multiple optical transmission members 50 converge at a single point on the central axis O (see Figure 4).

[0065] Furthermore, in the catheter device 100 of this embodiment, multiple second tip openings 12a are formed on the tapered side portion 13c of the recess 13. Multiple optical transmission members 50 can be used simultaneously to irradiate the biological tissue drawn into the recess 13 with a laser. This allows for a further reduction in the laser irradiation time required to complete the treatment.

[0066] Furthermore, as shown in Figure 3, in the catheter device 100 of this embodiment, a plurality of second tip openings 12a are arranged at equal intervals in the circumferential direction B on the tapered side surface 13c of the recess 13. More specifically, the plurality of second tip openings 12a in this embodiment are arranged such that the distance in the circumferential direction B between any two adjacent second tip openings 12a is equal. By doing so, variations in the laser irradiation intensity to the biological tissue drawn into the recess 13 can be suppressed in the circumferential direction B. This suppresses variations in treatment due to position in the circumferential direction B.

[0067] Next, a catheter device 200, which is another embodiment of the catheter device according to this disclosure, will be described. Figure 9A is a perspective view showing the tip of the catheter device 200. Figure 9B is a view of the tip of the catheter device 200 from the tip side.

[0068] The catheter device 200 of this embodiment differs from the catheter device 100 described above (see Figures 1 to 5) in the configuration of the elongated member 210, while other configurations are the same. Therefore, only the differences between the catheter device 200 and the catheter device 100 described above (see Figures 1 to 5) will be explained here, and the common configurations will not be described.

[0069] As shown in Figures 9A and 9B, the elongated member 210 of the catheter device 200 in this embodiment includes a tip portion 215 including a tip surface 10a, a main body portion 216 located on the proximal end side of the tip portion 215 and having a larger diameter than the tip portion 215, and a connecting portion 217 that connects the tip portion 215 and the main body portion 216, with the outer diameter decreasing from the main body portion 216 side toward the tip portion 215 side.

[0070] As shown in Figures 9A and 9B, the main body portion 216 of this embodiment defines a third lumen 218 on the radially C-outside of the longer member 210 than the second lumen 12, through which a different optical transmission member 250, separate from the optical transmission member 50 inserted into the second lumen 12, can be inserted. A third tip opening 218a connected to the third lumen 218 is formed on the outer surface of the connecting portion 217. The optical transmission member 250 inserted into the third lumen 218 may have the same configuration as the optical transmission member 50 inserted into the second lumen 12, or it may have a different configuration. For the sake of explanation, the optical transmission member 50 inserted into the second lumen 12 will be referred to as the "first optical transmission member 50," and the optical transmission member 250 inserted into the third lumen 218 will be referred to as the "second optical transmission member 250."

[0071] Thus, the elongated member 210 of this embodiment partitions a first lumen 11 through which the hooking member 30 is inserted, a second lumen 12 through which the first optical transmission member 50 is inserted, and a third lumen 218 through which the second optical transmission member 250 is inserted. The second optical transmission member 250 has a laser emission section 251 at its tip. More specifically, the second optical transmission member 250 of this embodiment has a laser emission section 251 on its tip surface. Therefore, in the catheter device 200, a laser can be emitted from the second optical transmission member 250 inserted into the third lumen 218 through the third tip opening 218a. As described above, the third tip opening 218a is formed on the outer surface of the connecting portion 217. Therefore, the laser emitted from the laser emission section 251 of the second optical transmission member 250 through the third tip aperture 218a can irradiate biological tissue radially C further outward than the laser emitted from the laser emission section 51 of the first optical transmission member 50 through the second tip aperture 12a. For this reason, depending on the size of the tumor, for example, laser irradiation from the second optical transmission member 250 through the third tip aperture 218a may be performed in addition to laser irradiation from the first optical transmission member 50 through the second tip aperture 12a.

[0072] Furthermore, as described above, since the third tip opening 218a is formed on the outer surface of the connecting portion 217, the third tip opening 218a is located proximal A2 in the longitudinal direction A compared to the position of the second tip opening 12a. Therefore, the laser emitted from the laser emission portion 251 of the second optical transmission member 250 toward the distal side A1 through the third tip opening 218a is attenuated before reaching the vicinity of the position of the second tip opening 12a in the longitudinal direction A. By utilizing this attenuation effect, for example, the degree of ablation by the laser from the second optical transmission member 250 can be made smaller than the degree of ablation by the laser from the first optical transmission member 50. This makes it possible to perform treatments such as increasing the degree of ablation in the portion forming the dome of the tumor and decreasing the degree of ablation in the portion forming the neck of the tumor adjacent to normal biological tissue. Alternatively, instead of utilizing the attenuation effect described above, the difference in the degree of burning can be achieved, for example, by making the laser intensity of the laser emitted from the laser emission section 251 of the second optical transmission member 250 less than the laser intensity of the laser emitted from the laser emission section 51 of the first optical transmission member 50.

[0073] Thus, according to the catheter device 200 of this embodiment, biological tissue located radially outside C relative to the biological tissue being ablated by the laser from the first optical transmission member 50 can be ablated by the laser from the second optical transmission member 250. According to the catheter device 200 of this embodiment, the degree of ablation of biological tissue by the laser from the first optical transmission member 50 and the degree of ablation of biological tissue by the laser from the second optical transmission member 250 can be easily made to differ.

[0074] The first lumen 11, second lumen 12, and third lumen 218 of this embodiment extend along the central axis O. However, the second lumen 12, like the catheter device 100 described above (see Figures 4 and 5), includes a curved portion 12b (see Figures 4 and 5) that extends inclined with respect to the longitudinal direction A near the second tip opening 12a. Similarly, the third lumen 218 of this embodiment also extends inclined with respect to the longitudinal direction A near the third tip opening 218a. Therefore, as shown by the dashed line in Figure 9A, the laser emission portion 251 of the second optical transmission member 250 can emit a laser in a direction inclined with respect to the longitudinal direction A. Specifically, the second optical transmission member 250 inserted into the third lumen 218 is positioned such that, at the location of the third tip opening 218a, the tip surface on which the laser emission portion 251 is provided faces in a direction inclined with respect to the longitudinal direction A. More specifically, the second optical transmission member 250 is positioned such that, at the position of the third tip opening 218a, the tip surface on which the laser emission unit 251 is provided faces inward in the radial direction C. This suppresses the emission of laser light from the laser emission unit 251 of the second optical transmission member 250 toward the distal side A1 along the longitudinal direction A. This suppresses the irradiation of biological tissue that is not the target of laser irradiation from the second optical transmission member 250. In particular, in this embodiment, each second optical transmission member 250 is positioned such that, at the position of the third tip opening 218a, the tip surface on which the laser emission unit 251 is provided faces inward in the radial direction C, so that the lasers from multiple second optical transmission members 250 converge at a single point on the central axis O. Furthermore, in this embodiment, the position on the central axis O where the lasers from multiple second optical transmission members 250 converge is distal to A1 than the position on the central axis O where the lasers from multiple first optical transmission members 50 converge (see Figure 4).

[0075] Furthermore, as shown in Figure 9B, in the catheter device 200 of this embodiment, multiple (eight in this embodiment) third lumens 218 are formed in the main body portion 216 of the elongated member 210. Multiple third tip openings 218a (eight in this embodiment) are formed in the connecting portion 217 of the elongated member 210. Therefore, in the catheter device 200 of this embodiment, multiple second optical transmission members 250 can be used simultaneously to irradiate biological tissue with a laser. This can shorten the laser irradiation time required to complete treatment.

[0076] Furthermore, as shown in Figure 9B, in the catheter device 200 of this embodiment, multiple third tip openings 218a are arranged in the circumferential direction B on the outer surface of the connecting portion 217. The multiple third tip openings 218a are also arranged at equal intervals in the circumferential direction B on the outer surface of the connecting portion 217. More specifically, the multiple third tip openings 218a in this embodiment are arranged such that the distance in the circumferential direction B between any two adjacent third tip openings 218a is equal. This suppresses variations in the irradiation intensity of the lasers irradiated onto the biological tissue from the multiple second optical transmission members 250 in the circumferential direction B. This reduces variations in treatment depending on the position in the circumferential direction B.

[0077] The catheter device relating to this disclosure is not limited to the specific configurations shown in the embodiments and modifications described above, and various modifications, changes, and combinations are possible as long as they do not depart from the scope of the claims. [Industrial applicability]

[0078] This disclosure relates to a catheter device. [Explanation of Symbols]

[0079] 10: Long components 10a: End surface of the long member 11: First Lumen 11a: 1st tip opening 12: Second Lumen 12a: 2nd tip opening 12b: Curved section 12c: Guide surface 13: Recess 13a: Bottom part 13b:Edge 13c: Tapered side section 20: Tubular body 21: Hub 21a: First insertion port 21b: Second insertion port 21c: Hub body 30: Hooking component 31: Tip of the hooking component 31a: Hook part 32: Main body of the hooking component 40: Wire rod 41: Free end of wire 42: Nail area 50: First optical transmission member 51: Laser emission section 100: Catheter device 200: Catheter device 210: Long member 210a: End surface of long member 215: Tip of a long member 216: Main body of long member 217: Connecting part of long member 218: Third Lumen 218a: 3rd tip opening 250: Second optical transmission member 251: Laser emission section 500: Laser Oscillator A: Long direction A1: Distal side A2: Proximal side B: Circumferential direction C: Radial direction O: Central axis AT: Artery X: Saccular aneurysm

Claims

1. A long member that separates the first lumen and the second lumen, A hooking member is provided at the tip, which can be hooked onto biological tissue, and which can be inserted into the first lumen. The device comprises a laser emission section at its tip capable of emitting a laser, and an optical transmission member that can be inserted into the second lumen, The aforementioned elongated member has a recess on its tip surface, On the inner surface of the recess, A first tip opening connected to the first lumen, A second tip opening connected to the second lumen is formed, The hooking member is such that the tip portion can be extended from the elongated member through the first tip opening to hook onto the biological tissue, and the biological tissue hooked by the hooking portion can be drawn into the recess when the tip portion is pulled back toward the first tip opening. The laser emission portion of the optical transmission member is capable of irradiating the biological tissue, which is drawn into the recess by the hooking member, with the laser through the second tip opening, in a catheter device.

2. The aforementioned recess is The bottom part, Edge and, It comprises a tapered side portion that decreases in diameter from the edge portion toward the bottom portion, The first tip opening is formed in the bottom surface portion of the recess, The catheter device according to claim 1, wherein the second tip opening is formed on the tapered side surface of the recess.

3. The catheter device according to claim 1 or 2, wherein the tip of the hooking member is deformable toward the radially outward direction of the elongated member by protruding from the first tip opening.

4. The catheter device according to claim 3, wherein the tip of the hooking member is housed in the first lumen in an elastically deformed state and can protrude from the first tip opening, thereby being deformable radially outward by a restoring force.

5. The aforementioned hooking member comprises multiple wires, The tip of the hooking member includes the multiple free ends of the multiple wires, The catheter device according to claim 3, wherein the plurality of free ends of the plurality of wires protrude from the first tip opening, thereby being deformable radially outward.

6. Each of the aforementioned multiple wires has a fan-shaped cross-section, The catheter device according to claim 5, wherein the plurality of wires are housed in the first lumen such that they form a circular cross-sectional shape as a whole.

7. The aforementioned elongated member is The tip portion including the aforementioned tip surface, Located on the base end side of the aforementioned tip, the main body portion has a larger diameter than the aforementioned tip, The device comprises a connecting portion that connects the tip portion and the main body portion, and whose outer diameter decreases from the main body portion side toward the tip portion side, The main body of the elongated member has a third lumen located radially outward from the second lumen, through which a light transmission member separate from the light transmission member can be inserted. The catheter device according to claim 1 or 2, wherein a third tip opening connected to the third lumen is formed on the outer surface of the connecting portion.

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