Systems and methods for measuring characteristics of the coronary artery system

By equalizing guidewire and catheter sensor pressures at counterintuitive positions relative to the stenosis, the method addresses sensor calibration drift in FFR and iFR measurements, enhancing accuracy and speed in assessing blood vessel conditions.

JP2026506876APending Publication Date: 2026-02-27スタリオン·カーディオ·エルエルシー
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Patent Information

Application Number
JP2025545152
Authority / Receiving Office
JP · JP
Patent Type
Applications
Current Assignee / Owner
Priority Date
2023-02-01
Filing Date
2024-01-30
Publication Date
2026-02-27

AI Technical Summary

Technical Problem

Conventional methods for determining fractional flow reserve (FFR) and instantaneous wave-free ratio (iFR) in blood vessels suffer from sensor calibration drift and are time-consuming, leading to inaccurate measurements and potential misdiagnosis of vessel conditions.

Method used

A method involving equalizing the guidewire sensor pressure to the catheter sensor pressure when positioned distal and proximal to the stenosis, respectively, followed by retracting the guidewire for measurement, thereby reducing sensor calibration shifts and streamlining the assessment process.

Benefits of technology

This approach enables faster and more accurate determination of stenosis characteristics, reducing the need for calibration checks and minimizing measurement time, while providing reliable indicators for clinicians.

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Abstract

Disclosed herein is a method for assessing a patient's blood vessel. The method can include equalizing a pressure measured by a guidewire sensor when the guidewire sensor is positioned within the blood vessel and distal to a stenosis in the blood vessel, and a catheter sensor when the guidewire sensor is positioned within the blood vessel and proximal to the stenosis to a pressure measured by a catheter sensor. After equalization, the guidewire sensor can be retracted so that both the guidewire sensor and the catheter sensor are positioned proximal to the stenosis, and pressure can then be measured by the guidewire sensor. The pressure measured by the guidewire sensor can be used to generate a display indicative of a characteristic of the stenosis. The display can be output for presentation to a clinician to enable the clinician to assess the stenosis.
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