High-throughput parallel detection method based on imaging flow cytometry and spatially encoded reagents
Patent Information
- Authority / Receiving Office
- JP · JP
- Patent Type
- Applications
- Current Assignee / Owner
- Filing Date
- 2023-10-07
- Publication Date
- 2026-03-05
AI Technical Summary
Current detection methods in biomedical analysis, such as flow cytometry and fluorescence microscopes, are limited in throughput and spatial resolution, unable to efficiently detect multiple biological particles or analytes simultaneously, particularly in liquid biopsies.
A high-throughput parallel detection method using imaging flow cytometry combined with spatially encoded reagents, where fluorescent microspheres of different colors and positions form encoding sequences, allowing for one-to-one correspondence with biological particles, enabling detection of nucleic acids, proteins, and single cells at high speeds.
Achieves high-throughput parallel detection of 102-105 different analytes per second, improving detection efficiency and accuracy for nucleic acids, proteins, and single cells in liquid biopsies.
Smart Images
Figure 2026507754000001_ABST