Phage-extracellular vesicle conjugate

The phage-EV conjugate addresses the challenge of impaired wound healing by providing targeted antibacterial and tissue repair functions through a cleavable linker, effectively preventing infections and promoting tissue regeneration.

JP2026518449APending Publication Date: 2026-06-08THE UNIV OF SYDNEY
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Patent Information

Authority / Receiving Office
JP · JP
Patent Type
Applications
Current Assignee / Owner
THE UNIV OF SYDNEY
Filing Date
2024-05-31
Publication Date
2026-06-08

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Abstract

The present invention relates to a phage-extracellular vesicle (EV) conjugate in which a phage is linked to an EV by a linker, and the phage and EV are independently conjugated to the linker by one or more types of cleavable bonds, and to a method for preparing a phage-EV conjugate. The present invention also relates to a method for using a phage-EV conjugate to promote tissue repair in an individual having damaged tissue, such as that associated with a bacterial infection.
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