A composition useful for slowing the decomposition of active compounds caused by light, heat, and / or oxidation.

Abstract

The present invention relates to a composition comprising compound A of formula (I) and compound B of formula (II); the use thereof for slowing or even preventing the decomposition of at least one active compound selected from photosensitive compounds, heat-sensitive compounds, and / or oxidation-sensitive compounds caused by light, heat, and / or oxidation; and formulations comprising the composition. JPEG2026519922000022.jpg6782

Description

[Technical Field]

[0001] The present invention relates to compositions capable of stabilizing photosensitive active compounds, heat-sensitive active compounds, or more broadly, oxidation-sensitive active compounds in pharmaceutical formulations, particularly cosmetics, skin cosmetics, pharmaceuticals, and / or household, industrial, and industrial detergent products ("Household, Industrial, and Industrial (HI&I) Products"). [Background technology]

[0002] In the fields of cosmetics, dermatological cosmetics, pharmaceuticals, and industry, many formulations typically contain one or more active compounds selected from pigments, odor molecules, UV filters, antioxidants, and vitamins. These active compounds are of natural or synthetic origin and are generally intended to improve the appearance, sensory quality, or functionality of the formulation.

[0003] For aesthetic reasons, such formulations are often packaged in transparent packaging, such as glass or plastic, but these packages transmit visible light and ultraviolet (UV) light.

[0004] As a result, active compounds that are sensitive to light, especially ultraviolet light, become more susceptible to degradation, which can alter the appearance and / or properties of the formulation.

[0005] In fact, exposure to ultraviolet light can induce radical reactions that alter the chemical structure of photosensitive compounds, such as pigments and odor molecules in perfumes. This can change the color and / or scent of the formulation, and may even lead to the loss of activity of active compounds.

[0006] A common solution to improve the stability of formulations against ultraviolet light is the use of UV filters.

[0007] As ultraviolet filters, compounds of the benzophenone family and other compounds that absorb ultraviolet light are particularly used, as described in, for example, Annex VI of the Cosmetic Regulation (EC) No. 1223 / 2009, Annex VII of CEE Directive No. 76 / 768 (on ultraviolet filters permitted in cosmetics), or the FDA (U.S. Food and Drug Administration) guidelines, namely the Federal Register, Volume 43, No. 166 (August 25, 1978).

[0008] However, benzophenones have been shown to have many drawbacks, such as causing severe yellowing upon introduction and sometimes requiring inadequate protection. They are toxic to many marine organisms and are classified as carcinogenic, mutagenic, and reproductively toxic (CMR).

[0009] More generally, organic UV filters are petrochemical-derived substances and are becoming increasingly controversial because, as in the case of ethylhexyl salicylate, they are suspected of having endocrine-disrupting effects.

[0010] However, these compounds are intended to protect the skin and hair from the harmful effects of ultraviolet light, and do not protect the formulation itself or photosensitive compounds such as odor molecules and pigments. “Cosmetic Additives,” 2 nd You can refer to the article "Filtres et ecrans solaires" by MC Poelman in the 1999 edition of Editions Tec & Doc, Paris. Using only a single UV filter in a formulation does not necessarily guarantee adequate and effective protection of the pigment from ultraviolet light.

[0011] Accordingly, European Patent No. 2985018 describes compositions that enable the stabilization of the color development of formulations in response to ultraviolet light. These compositions consist of combinations of three ultraviolet filters, each belonging to the cinnamate, dibenzoylmethane, and salicylate families. In the examples, a composition consisting of ethylhexyl methoxycinnamate, butyl methoxydibenzoylmethane, and ethylhexyl salicylate was used. However, ethylhexyl salicylate is suspected by European regulatory authorities to be an endocrine disruptor. Furthermore, this application does not mention the ability of compositions to protect other cosmetic active ingredients other than pigments.

[0012] Other factors, particularly heat and oxidation, can cause the decomposition of active compounds.

[0013] French Patent Application Publication No. 3023715 relates to a synergistic combination of at least two agents that enhance the photoprotective effect of at least one sunscreen filter, one of which is an enhancer of the photoprotective effect of the sunscreen filter against UVA and is selected from flavonoids and diarylheptanoids, and the other of which is an enhancer of the photoprotective effect of the sunscreen filter against UVB and is selected from phenolic acids and their derivatives. In the examples, a combination of pongamol and ferulic acid, and a combination of pongamol, ferulic acid, and paracoumaric acid are used.

[0014] However, the effects of these combinations are limited to their ability to protect sunscreen filters, and this application makes no mention of the ability of the combinations to protect other cosmetic active ingredients.

[0015] There is a need for the development of alternative stabilization compositions that limit the degradation of at least one active compound in the formulation caused by light, heat, and / or oxidation. [Overview of the project]

[0016] Therefore, one of the objectives of the present invention is to propose a composition that stabilizes formulations of the aforementioned type against the harmful effects of light, heat, and / or oxidation and is compatible with the active compounds present in these formulations.

[0017] In this context, the present invention particularly aims to provide a composition that stabilizes at least one active substance of a cosmetic, dermatological, pharmaceutical, or detergent product, which is a photosensitive compound, a thermosensitive compound, and / or an oxidation-sensitive compound, and is generally selected from odor molecules, dyes, vitamins, antioxidants, UV filters, and mixtures thereof.

[0018] For this purpose, the present invention relates to a composition comprising: (A) Compound A of formula (I): [Chemical formula] (where R 1 , R 2 , and R 3 independently of one another represent H, a hydroxy group, a C1-C4 alkyl group, or a C1-C4 alkoxy group); and (B) Compound B of formula (II): [Chemical formula] (where R represents a C1-C4 alkyl group).

[0019] Compound A is useful as an ultraviolet filter against UV-A radiation. Compound B is useful as an ultraviolet filter against UV-B radiation.

[0020] In the context of this specification, the term "ultraviolet filter" (or "UV filter") means a compound that can absorb electromagnetic radiation within the range included in the ultraviolet radiation region, that is, within the wavelength range of 10 nanometers to 400 nanometers. In particular, ultraviolet UV-A radiation with a wavelength of 315 nanometers to 400 nanometers and ultraviolet UV-B radiation with a wavelength of 280 nanometers to 315 nanometers are distinguished.

[0021] Furthermore, the present invention relates to the use of the aforementioned types of compositions for slowing down or even preventing the decomposition of at least one active compound in a formulation, selected from photosensitive compounds, heat-sensitive compounds, and / or oxidation-sensitive compounds, which is caused by light, heat, and / or oxidation, wherein the active compound is preferably selected from odor molecules, dyes, vitamins, antioxidants, UV filters, and mixtures thereof.

[0022] The present invention relates to the use of the composition defined above for protecting at least one such active compound from decomposition caused by light, heat, and / or oxidation.

[0023] Furthermore, the present invention relates to a formulation comprising 0.05 to 5.00% by weight of the aforementioned type of composition and at least one active compound selected from photosensitive compounds, heat-sensitive compounds, and / or oxidation-sensitive compounds, preferably odor molecules, dyes, vitamins, antioxidants, UV filters, and mixtures thereof.

[0024] The formulations according to the present invention may be formulations of cosmetics, skin cosmetics, pharmaceuticals, or household, industrial, and facility detergent products ("Household, Industrial, and Facility (HI&I) Products"). [Modes for carrying out the invention]

[0025] The inventors have found that the combination of compound A and compound B very effectively stabilizes the active compound in the formulation against light, particularly ultraviolet radiation. The inventors have surprisingly found that the combination of compound A and compound B is suitable for reducing the decomposition of at least one active compound commonly used in the formulations of cosmetics, skin cosmetics, pharmaceuticals, and / or household, industrial, and institutional detergent products ("household, industrial, and institutional (HI&I) products"). The active compound is selected from photosensitive compounds, thermosensitive compounds, and / or oxidation-sensitive compounds, preferably from fragrance molecules, dyes, vitamins, antioxidants, UV filters, and mixtures thereof, preferably from dyes, fragrance molecules, and mixtures thereof, particularly preferably from dyes.

[0026] Compound A, which is useful as a UV-A filter, belongs to the dibenzoylmethane family. Compound A corresponds to formula (I):

Chem.

[0027] In particular, compound A corresponds to formula (Ia):

Chem.

Chem.

[0028] Furanoflavonoids, more specifically pongamol, are derived from leguminous plants, particularly species such as Pongamia pinnata, Pongamia glabra, Millettia pinnata, Derris indica, Gadelupa pinnata, Pongamia grandifolia, Robinia mitis, Tephrosia purpurea, Tephrosia hamiltoni, Tephrosia falciformis, Tephrosia vogellii, and Tephrosia lanceolata. Among these species, pongamol is primarily found in the seeds, more specifically in the oil of these seeds, generally accounting for about 27–39% by weight of the oil. Pongamol can be obtained by mechanical or chemical extraction. Pongamol is typically in the form of karanja oil, extracted from the seeds, or it can also be produced by synthetic chemistry.

[0029] Preferably, compound A is in the form of a seed extract of Pongamia pinnata, in which the weight concentration of pongamol is preferably more than 70%, more specifically more than 95%, relative to the weight of the extract.

[0030] Compound B, which is useful as a UV-B ultraviolet filter, belongs to the cinnamic acid derivative family. Compound B is identical to formula (II): [ka] In the formula, R represents a C1-C4 alkyl group. Preferably, R represents a C1-C3 alkyl group, particularly Et.

[0031] Preferably, compound B corresponds to formula (IIa): [ka]

[0032] In a particularly favorable way, compound B is ethyl p-methoxycinnamate of formula (IIb): [ka]

[0033] Ethyl p-methoxycinnamate is a compound that can be found in nature. In fact, ethyl p-methoxycinnamate is naturally present in plants of the ginger family and is more commonly used in Southeast Asia as a spice, seasoning, and herb. This is especially true for species such as turmeric (Kaempferia galanga) and galangal (Alpinia galanga), whose essential oils from the rhizomes contain 0.1% to 30.0% ethyl p-methoxycinnamate.

[0034] Preferably, the p-ethyl methoxycinnamate is in the form of an extract of turmeric root, where the weight concentration of p-ethyl methoxycinnamate is preferably more than 70%, more specifically more than 98%.

[0035] The above composition contains compound A and compound B in proportions that can vary widely.

[0036] However, a preferred composition is one in which, relative to the total weight of compound A and compound B, Compound A in an amount of 5-95% by weight; and Compound B in an amount of 5-95% by weight, Includes.

[0037] This composition is particularly effective in protecting at least one active compound in the formulation from degradation by light, especially ultraviolet light, and / or heat and / or oxidation.

[0038] With respect to the total weight of compound A and compound B, Compound A in 20-95% by weight; and Compound B in a concentration of 5-80% by weight. A composition containing is particularly preferred.

[0039] Advantageously, the above composition is, relative to the total weight of compound A and compound B, 30-85% by weight of compound A; and Compound B at 15-70% by weight, Includes.

[0040] According to a preferred embodiment, the above composition is, with respect to the total weight of compound A and compound B, 45-75% by weight of compound A; and Compound B at 25-55% by weight, Includes.

[0041] Therefore, according to a particular embodiment, the above composition is, with respect to the total weight of compound A and compound B, 50-70% by weight of compound A; and 30-50% by weight of compound B, Includes.

[0042] Generally, the combined proportion of compound A and compound B accounts for 20% to 100% by weight, particularly 50% to 100% by weight, and preferably 70% to 100% by weight, relative to the weight of the composition.

[0043] Compounds A and B are soluble in most organic solvents, particularly alcohols or esters. Compounds A and B can also be solubilized in or within the active compound to be stabilized.

[0044] It may be desirable to introduce the above composition into an aqueous formulation or a formulation containing a hydrophilic phase, particularly an aqueous phase (typically an emulsion). For this purpose, the above composition may contain one or more ionic or nonionic surfactants. Surfactants with an HLB of 12 or higher are preferred because they promote the solubilization of compounds A and B in the aqueous phase.

[0045] The above composition may also contain a solubilizer that promotes the complete or partial dissolution of compounds A and B, enabling the acquisition of a liquid or paste-like composition. This solubilizer is preferably a compound or mixture of compounds commonly used in cosmetics, skin cosmetics, pharmaceuticals, or industrial applications. Typically, the solubilizer is an organic solvent, such as an alcohol or ester.

[0046] Depending on the properties, purity, origin, and proportion of compound A and compound B, as well as the properties and proportion of any additional compounds (such as solubilizers and surfactants), the above composition may take the form of a solid or a liquid, and the form of the composition can be adapted according to the intended use.

[0047] In one embodiment, the above composition consists of: Compound A and Compound B, Furthermore, optionally, surfactants, solubilizers, or mixtures thereof.

[0048] In its simplest form, the above composition consists of compound A and compound B.

[0049] In preferred embodiments, the composition comprises (or consists of) pongamol and ethyl p-methoxycinnamate, and optionally a surfactant, a solubilizer, or a mixture thereof.

[0050] The above composition may include (or consist of): Pongamia pinnata seed extract containing pongamol, typically at least 27% by weight, preferably at least 70% by weight, relative to the weight of the Pongamia pinnata seed extract. A turmeric root extract comprising, typically at least 0.1% by weight, preferably at least 70% by weight, of ethyl p-methoxycinnamate, relative to the weight of the turmeric root extract.

[0051] According to a second aspect, the present invention relates to the use of the composition defined above for slowing or even preventing the decomposition of at least one active compound in a formulation, selected from photosensitive compounds, heat-sensitive compounds, and / or oxidation-sensitive compounds, which is caused by light, heat, and / or oxidation, wherein the active compound is preferably selected from odor molecules, dyes, vitamins, antioxidants, UV filters, and mixtures thereof, and more particularly from dyes, odor molecules, and mixtures thereof.

[0052] The present invention also relates to the use of the composition defined above for protecting at least one such active compound from decomposition caused by light, heat, and / or oxidation.

[0053] Examples of photosensitive and heat-sensitive compounds include dyes. Particularly those approved in Annex IV of the Cosmetic Regulations, and preferably including FD&C Yellow 5, FD&C Yellow 6, FD&C Yellow 10, FD&C Red 4, D&C Red 33, FD&C Red 40, FD&C Orange 4, Ext D&C Violet 2, FD&C Blue 1, and any other synthetic dyes commonly used in the intended application, as well as mixtures thereof, are examples of dyes most commonly used in fine perfumes and rinse-off products.

[0054] The pigments may be of natural origin and include, for example, carmine, caramel, annatto (including bixin and norbixin), turmeric (including curcuminoids (curcumin, demethoxycurcumin, and bisdemethoxycurcumin)), spirulina and its phycobiliproteins, anthocyanidins and their heterosides (anthocyanins), betalains (including betacyanins (such as betanin) and betaxanthins (such as indicaxanthin)), carotenoids (including β-carotene, capsanthin, and capsorbin), free or complexed chlorophyll and chlorophyllin, xanthophyll (including astaxanthin and lutein), or any other natural molecule with coloring properties.

[0055] The active compound may also be an odor molecule.

[0056] The present invention relates, in particular, to the use of the compositions defined above for stabilizing fragrance molecules of a formulation, preferably a perfume formulation, from the harmful effects of visible light, ultraviolet light, temperature, or any other oxidation mechanism, thereby preventing their decomposition.

[0057] For example, odor molecules belonging to the following families: esters (including geranyl acetate, isoamyl acetate, pentyl butyrate, or ethyl butyrate), linear terpenes (including geraniol, myrcene, citral, or linalool) and cyclic terpenes (including limonene, menthol, camphor, or eucalyptol), aromatic compounds (including eugenol, vanillin, anisole, or benzaldehyde), amines (including pyridine, indole, or cadaverine), alcohols (furaneol or 1- These include hexanol, aldehydes (including acetaldehyde, furfural, or hexyl cinnamaldehyde), ketones (including dihydrojasmone or cyclopentadecanone), lactones (including jasmine lactone, sotolon, or γ-decalactone), thiols (including furan-2-ylmethanethiol, allylthiol, or thioacetone), essential oils such as bergamot, eucalyptus, orange, lemon, lavender, geranium, almond, or mixtures thereof.

[0058] The active compound may be a vitamin or antioxidant (e.g., ascorbic acid, tocopherol, retinol, niacinamide, or derivatives thereof) and / or a UV filter (such as avobenzone, octocrylene, ethylhexyl salicylate, ethylhexyl triazone, bis-ethylhexyloxyphenol methoxyphenyl triazine, phenylbenzimidazole sulfonic acid, or diethylhexyl butamide triazone).

[0059] The present invention further relates to a method for slowing down or even preventing the degradation of at least one active compound selected from photosensitive compounds, heat-sensitive compounds, and / or oxidation-sensitive compounds, which is caused by light, heat, and / or oxidation, the method comprising contacting the active compound (or formulation, in particular a cosmetic containing such an active compound) with the composition defined above.

[0060] According to a third aspect, the present invention relates to a formulation comprising 0.05% to 5.00% by weight of the aforementioned type of composition and at least one active compound selected from photosensitive compounds, heat-sensitive compounds, and / or oxidation-sensitive compounds, preferably selected from odor molecules, dyes, vitamins, antioxidants, UV filters, and mixtures thereof.

[0061] The above-mentioned formulations may be cosmetics, skin cosmetics, pharmaceuticals, or formulations for household, industrial, and institutional use.

[0062] In particular, the above-mentioned formulation may contain 0.05% to 1.00% by weight, especially 0.05% to 0.30% by weight, preferably 0.10% to 0.20% by weight, for example 0.15% by weight, based on the total weight of the formulation.

[0063] The above-mentioned formulation may be a hydrophilic formulation, such as an aqueous formulation, an alcoholic formulation, a water-alcoholic formulation, or an oily formulation. The above-mentioned formulation may be single-phase or two-phase. For example, the formulation may be in the form of an emulsion and may contain an oily phase and a hydrophilic phase, particularly an aqueous phase. The above-mentioned formulation may be a cream, gel, serum, mist, or lotion.

[0064] Advantageously, the formulation contains at least 10% alcohol, preferably ethanol, relative to the weight of the formulation. In this case, the composition can be solubilized within the formulation, resulting in the formation of a single homogeneous phase, similar to water-alcohol formulations such as perfumes, eau de parfums, eau de toilettes, and eau de colognes. In this case, the presence of a surfactant within the composition or emulsion is not required.

[0065] If the above formulation contains an oily phase, the presence of a surfactant promotes the dispersion of the composition within the formulation. The composition typically appears as microdroplets and forms a dispersed phase within the formulation. In this case, the composition preferably contains a surfactant and / or the formulation preferably contains a surfactant. The surfactant is as defined above.

[0066] The above-mentioned preparations may be perfumes (containing at least 10% alcohol, or less than 10% alcohol, such as alcohol-free perfumes), or care and hygiene products for the face, body, and / or hair.

[0067] The above-mentioned formulation is preferably a perfume.

[0068] Other advantages and features of the present invention will become apparent from the following embodiments.

[0069] Example 1: Preparation of composition and formulation The compositions tested were combinations of a UV A absorbing material, avobenzone (or butyl methoxydibenzoylmethane) (for comparison), or Pongamia pinnata seed extract (hereinafter referred to as "Pongamia extract" or compound A), and a UV B absorbing material, OMC (or ethylhexyl methoxycinnamate) (for comparison), or Kaempferia galanga root extract (hereinafter referred to as "Galanga extract" or compound B). These compositions are listed in Table 1. Table 1 shows the weight ratio of the compounds in the compositions, and the above compositions consist only of these compounds (no solvents or surfactants are added).

[0070] For the compound avobenzone, Eusolex 9010 (Merck) (avobenzone ratio over 95%) or Parsol 1789 (DSM) (avobenzone ratio over 95%) was used. For the pongamia extract, Pongamol (Indfrag Biosciences) (pongamol ratio over 95%) was used. For the galangal extract, we used galangal extract (Sabinsa) (p-ethyl methoxycinnamate ratio exceeding 98%). [Table 1]

[0071] To evaluate and demonstrate performance, 0.15% by weight of one of compositions 1 to 29 was added to different formulations. These formulations had the compositions detailed in Table 2, and the percentages are weight ratios to the weight of the formulation. [Table 2]

[0072] Formulations F1, F2, and F3 were measured using a transmission spectrophotometer CM-5 (Konica Minolta Corporation), L * a * b. Characterization was performed using the D65 colorimetric standard in accordance with the CIE 1976 standard, i.e., CIELAB 1976. Here, L * This axis represents brightness or lightness: the value ranges from 0, representing no light (black), to 100, representing sufficient light (white); a * The values ​​represent the axis from green (-100) to red (+100); b * The values ​​represent the axis from blue (-100) to yellow (+100).

[0073] Next, the above formulation is placed in an accelerated UV aging chamber (Suntest) for 24 hours, and the color is measured again to evaluate the difference between the samples before and after the UV stability test. Then, the ΔE value is calculated using the following formula:

number

[0074] Example 2: Stabilization test of perfume formulation F1 [Table 3]

[0075] The results shown in Table 3 demonstrate that F1 formulations containing extracts rich in compound A and extracts rich in compound B are more stable than F1 formulations containing the UV filter avobenzone / OMC or avobenzone / compound B, regardless of the ratio (compound exhibiting anti-UV-A properties:compound exhibiting anti-UV-B properties) from 10:1 to 1:5.

[0076] Among the compositions according to the present invention, comprising compound A and compound B, compositions 06, 09, 12, 15, and 18 exhibited the most interesting color protection performance, with values ​​of 54.6%, 67.3%, 64.1%, 60.1%, and 60.2%, respectively. These performances are superior to those of compound A alone and compound B alone, which are 48.4% and -3.1%, respectively.

[0077] Example 3: Stabilization test of perfume formulation F2 [Table 4]

[0078] The results shown in Table 4 demonstrate that formulations F2, which are identical to F1 except for the use of a different dye (FD&C Red 33), containing extracts rich in compound A and extracts rich in compound B, are more stable than formulations F2 containing the UV filter avobenzone / OMC or avobenzone / compound B, regardless of the ratio (compound exhibiting anti-UV-A properties:compound exhibiting anti-UV-B properties) from 10:1 to 1:5. Among the preferred compositions containing compound A and compound B, compositions 06, 09, 12, 15, 18, 21, 24, and 27 showed interesting color protection performance, with percentages of 40.2%, 41.4%, 43.6%, 43.0%, 42.8%, 42.7%, 44.4%, and 36.4%, respectively. These performances are superior to those of compound A alone and compound B alone, which were 35.3% and 0.7%, respectively.

[0079] Example 4: Stabilization test of perfume formulation F3 [Table 5]

[0080] The results shown in Table 5 demonstrate that formulation F3, which is identical to F2 except for the use of a different fragrance (Diamond Beauty), and contains extracts rich in compound A and compound B, is more stable than formulation F3 containing the UV filter avobenzone / OMC or avobenzone / compound B, regardless of the ratio (compound exhibiting anti-UV-A properties:compound exhibiting anti-UV-B properties) from 10:1 to 1:5.

[0081] Among preferred compositions containing compound A and compound B, compositions 06, 09, 12, 15, 18, 21, and 24 exhibited interesting color protection performance, with values ​​of 59.3%, 61.0%, 61.0%, 60.5%, 58.6%, 56.8%, and 56.1%, respectively. These performances are superior to those of compound A alone and compound B alone, which were 55.9% and 3.4%, respectively.

Claims

1. (A) Compound A of formula (I), 【Chemistry 1】 (B) Compound B of formula (II), 【Chemistry 2】 Includes, R １ , R ２ , and R ３ These are H, hydroxyl group, and C, independently of each other. １ ~C ４ Alkyl alkyl group, or C １ ~C ４ Represents an alkoxy group; R is C １ ~C ４ represents an alkyl group, composition.

2. R １ , R ２ , and R ３ The composition according to claim 1, wherein each of the following elements independently represents H, -OH, Me, or OMe.

3. Compound A matches formula (Ia), 【Transformation 3】 R ２ This is as defined in claim 1 or claim 2, The composition according to claim 1 or 2.

4. Compound A is pongamol of formula (Ib). 【Chemistry 4】 The composition according to claim 2 or 3.

5. R is C １ ~C ３ The composition according to any one of claims 1 to 4, wherein the alkyl group, preferably Et, is represented.

6. Compound B matches formula (IIa), 【Transformation 5】 R is as defined in claim 1 or 5. The composition according to any one of claims 1 to 5.

7. Compound B is ethyl p-methoxycinnamate of formula (IIb). 【Transformation 6】 The composition according to claim 6.

8. With respect to the total weight of compound A and compound B, Compound A in an amount of 5% to 95% by weight, preferably 20% to 95% by weight, particularly 30% to 85% by weight, particularly preferably 45% to 75% by weight, for example 50% to 70% by weight; and Compound B in an amount of 5% to 95% by weight, preferably 5% to 80% by weight, particularly 15% to 70% by weight, particularly preferably 25% to 55% by weight, for example 30% to 50% by weight, A composition according to any one of claims 1 to 7, comprising:

9. Use of the composition according to any one of claims 1 to 8 for slowing down or even preventing the decomposition of at least one active compound in a formulation, selected from photosensitive compounds, heat-sensitive compounds, and / or oxidation-sensitive compounds, caused by light, heat, and / or oxidation, wherein the active compound is preferably selected from odor molecules, pigments, vitamins, antioxidants, UV filters, and mixtures thereof.

10. A formulation comprising 0.05 to 5.00% by weight of a composition according to any one of claims 1 to 8, and at least one active compound selected from photosensitive compounds, heat-sensitive compounds, and / or oxidation-sensitive compounds, wherein the active compound is preferably selected from odor molecules, dyes, vitamins, antioxidants, UV filters, and mixtures thereof.

11. The formulation according to claim 10, which is a cosmetic, skin cosmetic, pharmaceutical, or formulation for household, industrial, and institutional use.

Images