Crosslinkable liquid compositions used in methods for treating or preventing eye disorders

JP2026519953APending Publication Date: 2026-06-19UNIVERSITEIT ANTWERPEN +1

Patent Information

Authority / Receiving Office
JP · JP
Patent Type
Applications
Current Assignee / Owner
UNIVERSITEIT ANTWERPEN
Filing Date
2024-04-26
Publication Date
2026-06-19

AI Technical Summary

Technical Problem

Current methods for correcting refractive errors and protecting against UV and HEV light exposure have limitations such as tissue removal risks, reversibility issues, and irreversible solutions like intraocular lenses, along with complications from laser surgery and blue light filters.

Method used

A crosslinkable liquid composition comprising gelatin functionalized with tyrosine derivative or phenol groups and a visible light and/or UV light photoinitiator system is applied to the cornea, crosslinked in situ, forming corneal inlays or onlays that provide UV and HEV light blocking properties, allowing for rapid treatment and correction of corneal curvature without tissue removal.

Benefits of technology

The method offers a long-lasting, reversible solution for treating refractive errors and protecting against UV and HEV light, reducing postoperative complications and providing a wider treatment range than laser surgery, with rapid crosslinking dynamics and immediate protection from harmful light.

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Abstract

The present invention relates to a crosslinkable liquid composition used in a method for therapeutically or prophylactically treating an eye disorder in a target eye, or in a surgical method for preparing a corneal onlay on a target eye or a corneal inlay inside a target eye, the crosslinkable liquid composition comprising a crosslinkable biomaterial containing gelatin functionalized with one or more tyrosine derivative groups or phenol groups, and a visible light and / or UV light photoinitiator system.
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