A monitoring system for detecting blood clot formation.

Abstract

The present invention relates to the technical field of medical devices, and more specifically to a monitoring system for detecting the formation of lower extremity venous thrombosis. The monitoring system includes a signal acquisition module and an ultrasound hardware system. The signal acquisition module acquires ultrasound detection data of a subject by transmitting and receiving ultrasound between multiple ultrasound probes and the subject, and transmits the ultrasound detection data to the ultrasound hardware system by forming it into an analog signal via 128 channels in the ultrasound probes. The ultrasound hardware system includes a multiplexer module, an analog signal processing module, a beamforming module, and a host computer module. This facilitates medical personnel in monitoring lower extremity venous thrombosis in patients, and by providing multiple ultrasound probes, it is possible to monitor veins in different parts of the patient, avoid complicated operations during detection, and detect thrombi in veins at multiple locations in the patient in real time.

Description

TECHNICAL FIELD

[0001] The present invention relates to the technical field of medical devices, and specifically, to a monitoring system for detecting thrombus formation. BACKGROUND ART

[0002] Deep venous thrombosis (DVT) of the lower extremities is a highly prevalent disease in acutely and critically ill patients as well as patients undergoing orthopedic surgery, and often causes life-threatening Pulmonary Embolism (PE). Even if a patient survives a PE attack, the risk of chronic thromboembolic pulmonary hypertension still exists, which can cause the patient to die within 2 to 3 years after the initial attack. Therefore, early diagnosis of DVT and prompt implementation of corresponding clinical decisions help reduce the incidence and mortality of thrombus in patients and improve prognosis. Currently, in related research at home and abroad, there is no effective monitoring and early warning means for DVT, and the establishment of a real-time, convenient and accurate DVT monitoring method is extremely important.

[0003] Ultrasonic examination of the patient's lower extremity veins generally requires a conventional bedside ultrasonic device, is operated by a specialized ultrasound physician, has a complicated process, and cannot realize real-time dynamic monitoring.

[0004] In the prior art, Chinese Patent Application CN103721348A discloses an ultrasonic monitoring and treatment apparatus and an ultrasonic monitoring device. The ultrasonic monitoring and treatment apparatus includes an ultrasonic medium containing unit for accommodating an ultrasonic transmission medium, an ultrasonic monitoring probe that emits ultrasonic waves for imaging with its emission surface located inside the ultrasonic medium containing unit, an ultrasonic treatment head that emits ultrasonic waves for treatment with its emission surface located inside the ultrasonic medium containing unit, a sound absorbing material containing unit that is located inside the ultrasonic medium containing unit and includes a flexible acoustically transparent film that seals a liquid sound absorbing material capable of absorbing ultrasonic waves, and a sound absorbing material filling and discharging unit that fills the liquid sound absorbing material into the sound absorbing material containing unit or discharges the liquid sound absorbing material from the sound absorbing material containing unit.

[0005] Chinese Patent CN215458154U discloses a portable ultrasonic detection device applicable to the human body or animals, the portable ultrasonic detection device comprising a host and a display, the host comprising a case rotatably connected to the display and an operating panel mounted on the case, the case comprising a first side, a second side provided on the opposite side of the first side, and a periphery connecting the first side and the second side, the operating panel provided on the first side, the host further comprising a cushioning protective member, the periphery comprising at least two edges and a corner smoothly connected between two adjacent edges, the cushioning protective member comprising a corner protector covering the corner. By providing a cushioning protective member on the host case, if the host falls, the cushioning protective member covering the outside of the host case will first contact the ground, thereby effectively cushioning the impact force the host will receive when it falls to the ground, and further effectively reducing the phenomenon of the host being damaged when it falls.

[0006] In conventional technology, improvements have been made to the convenience of using ultrasound detection and the resistance of the device to damage through the use of ultrasound and the components of the ultrasound device. However, ultrasound devices generally require operation by a specialized ultrasound physician, the operation process is complex, and real-time dynamic monitoring cannot be achieved. To address the above problems, the present invention provides a monitoring system for detecting thrombus formation. This system enables real-time dynamic monitoring of changes in the lower limb veins by fixing a patch-shaped transducer and a solid coupling gel to the skin surface corresponding to the patient's lower limb veins with adhesive tape, thereby solving the problem of the complex operation process for detecting lower limb venous thrombosis and the inability to monitor it in real time. [Overview of the project] [Problems that the invention aims to solve]

[0007] The monitoring system for detecting thrombus formation involves placing an ultrasound detection device within an ultrasound probe, forming it into a patch, and attaching it to the patient's lower limb veins for monitoring. Hardware processing displays the condition of the patient's lower limb veins on a host computer in real time, thereby simplifying the process of detecting lower limb venous thrombosis and enabling real-time monitoring of multiple sites. This completes the present invention. [Means for solving the problem]

[0008] Appearance 1 According to the present invention, A monitoring system for detecting the formation of lower extremity venous thrombosis is provided, including a signal acquisition module and an ultrasound hardware system.

[0009] The signal acquisition module acquires ultrasound detection data of the area under examination by transmitting and receiving ultrasound between multiple ultrasound probes and the area under examination, and transmits the ultrasound detection data to the ultrasound hardware system by forming it into an analog signal via 128 channels in the ultrasound probe. The ultrasonic hardware system includes a multiplexer module, an analog signal processing module, a beamforming module, and a host computer module.

[0010] The multiplexer module receives 128 channels of analog signals output from multiple ultrasound probes transmitted from the signal acquisition module, selects 128 channels of analog signals from one ultrasound probe, allows only the selected 128 channels of analog signals from that probe to pass through, and transmits the 128 channels of analog signals to the analog signal processing module. The selection of the multiple ultrasound detection data is made based on the actual observation needs of the examination site. The analog signal processing module receives the selected 128 channels of analog signals, performs low-noise amplification, noise reduction filtering, variable gain amplification, and analog-to-digital signal conversion on each channel's analog signal, and finally converts it into digitized 128-channel, 12-bit channel data, which is then transmitted to the beamforming module. The beamforming module receives digitized 128-channel, 12-bit channel data, performs delay compensation on each channel's channel data to align the phase of the compensated digitized 128-channel, 12-bit channel data based on the delay time calculated by the monitoring system, then combines the delay-compensated digitized 128-channel, 12-bit channel data into one channel's data through addition, performs IQ demodulation and low-pass filtering on the combined beam signal data to obtain baseband IQ data within a specific bandwidth range. Image preprocessing, including envelope extraction and logarithmic compression, is performed on the aforementioned baseband IQ data to obtain displayable image data. The processed image data is transmitted to the host computer module.

[0011] The host computer module displays the processed digital signal on the host computer in the form of the image data.

[0012] Furthermore, the host computer may also be a display.

[0013] Furthermore, the host computer module performs interactive control over the ultrasonic hardware system, specifically by controlling the multiplexer module to select the analog signals to be passed through.

[0014] Furthermore, the host computer module issues commands to the ultrasonic hardware system to control signal acquisition by the signal acquisition module, and the acquisition method involves the user controlling the activation of the scanning function of multiple probes via the host computer module.

[0015] One embodiment of the present invention is as follows: The host computer module issues a command 1 to the ultrasound hardware system via WIFI, causing the multiplexer module to select only probe 1, scan for S seconds, pause for G seconds, and upload the image of probe 1 to the host computer in real time. Next, the multiplexer module issues a command 2, causing it to select only probe 2, scan for S seconds, pause for G seconds, and upload the image of probe 2 to the host computer in real time. Finally, the multiplexer module issues a command 3, causing it to select only probe 3, scan for S seconds, pause for G seconds, and upload the image of probe 3 to the host computer in real time. After that, the host computer module controls the multiplexer module to switch back to probe 1, and so on, until the active time of the scanning function of the three probes exceeds T seconds. In this manner, the software controls the monitoring system to stop scanning, and the host computer module acquires image data from each of the three probes.

[0016] Appearance 2 According to the present invention, A monitoring device for detecting the formation of lower extremity venous thrombi is provided, including a detection assembly, a detection host 1, and a host computer 2.

[0017] The detection assembly includes the signal acquisition module described in embodiment 1, the ultrasonic detection probe is a patch probe 3, one end of which is connected to a data cable 4 and data-connected to the detection host 1 via a plug. Said detection host 1 includes a control motherboard 1008, a heat sink 1006, a power converter 1007 and a housing 1003, Said control motherboard 1008, said heat sink 1006 and said power converter 1007 are arranged inside said housing 1003, Said control motherboard 1008 is mounted with the ultrasonic hardware system according to Embodiment 1, which analyzes and processes various data, controls other electrical devices in the monitoring apparatus, and is responsible for information transmission.

[0018] Said housing 1003 is connected in a fitting manner to form a cavity inside said detection host 1.

[0019] One side of said housing 1003 is provided with an exposed switch 1001 which is the power switch of said detection host 1, One side of said housing 1003 is perforated with a connection port 1002 for connecting to external detection equipment to realize signal transmission, Inside said detection host 1, a battery 1005 for supplying power to other energized devices in the monitoring apparatus is provided, Said heat sink 1006 is used to dissipate heat from said control motherboard 1008 to prevent it from overheating, Said power converter 1007 converts power during charging to store electrical energy in said battery 1005.

[0020] Said host computer 2 is in signal connection with said detection host 1, and is used to display related images and information, The top surface of said detection host 1 is provided with a connection plate 5 and a support plate 6 for supporting said connection plate 5, one side of said connection plate 5 is rotatably connected to said detection host 1, and is connected to said host computer 2 by magnetic attraction. Effects of the Invention

[0021] Compared with the prior art, the monitoring system for detecting thrombus formation according to the present invention has the following technical advantages.

[0022] The monitoring system for detecting thrombus formation according to the present invention facilitates the monitoring of lower extremity venous thrombosis by medical professionals by performing ultrasound detection on the patient's lower extremity veins using a patch probe. By providing multiple ultrasound probes, it is possible to monitor veins in different parts of the patient's body, avoid complicated operations during detection, and detect thrombi in veins at multiple locations in the patient's body in real time.

[0023] Other features and advantages of the present invention will be described in detail in the following specific embodiments. [Brief explanation of the drawing]

[0024] [Figure 1] This is a block diagram of the overall configuration of the monitoring system for detecting thrombus formation according to the present invention. [Figure 2] This is a schematic diagram of the overall configuration of a monitoring device for detecting thrombus formation according to the present invention. [Figure 3] This is a schematic diagram of the structure of a monitoring device according to the present invention that detects the formation of a thrombus after the host computer has been removed. [Figure 4] This is a schematic diagram of a monitoring device according to the present invention for detecting the formation of a thrombus after the connecting plate has been removed. [Figure 5] This is a schematic diagram of a monitoring device according to the present invention for detecting the formation of a thrombus after the support plate has been folded. [Figure 6] This is a schematic diagram of the internal structure of a monitoring device for detecting thrombus formation according to the present invention. [Figure 7] This is a schematic diagram of the internal structure of a monitoring device for detecting thrombus formation according to the present invention. [Figure 8A] This is a schematic diagram of normal lower limb veins under two-dimensional conditions in Embodiment 2 of the present invention. [Figure 8B] This is a schematic diagram of normal lower limb veins under two-dimensional conditions in Embodiment 2 of the present invention. [Figure 9A] This is a schematic diagram of a lower limb vein where a thrombus has formed under two-dimensional conditions in Example 2 of the present invention. [Figure 9B]This is a schematic diagram of a lower limb vein where a thrombus has formed under two-dimensional conditions in Example 2 of the present invention. [Figure 10A] This is a schematic diagram of normal lower limb veins under color Doppler conditions in Example 2 of the present invention. [Figure 10B] This is a schematic diagram of normal lower limb veins under color Doppler conditions in Example 2 of the present invention. [Figure 11A] This is a schematic diagram of a lower limb vein where a thrombus has formed under color Doppler conditions in Example 2 of the present invention. [Figure 11B] This is a schematic diagram of a lower limb vein where a thrombus has formed under color Doppler conditions in Example 2 of the present invention. [Figure 12A] This is a schematic diagram of the lower limb veins under spectral Doppler conditions in Example 2 of the present invention. [Figure 12B] This is a schematic diagram of the lower limb veins under spectral Doppler conditions in Example 2 of the present invention. [Figure 13] This is a schematic diagram of beamforming in a monitoring device for detecting thrombus formation in Example 1 of the present invention. [Figure 14] This is a schematic diagram of the demodulation filtering of a monitoring device for detecting thrombus formation in Example 1 of the present invention. [Modes for carrying out the invention]

[0025] To further explain the technical means and effects used by the present invention to achieve a predetermined objective, specific embodiments, structures, features, and effects of the present invention will be described in detail below with reference to the drawings and preferred embodiments.

[0026] Example 1: Monitoring device for detecting thrombus formation As shown in Figures 1-7, 13 and 14, A monitoring device that detects the formation of blood clots is Includes a detection assembly, detection host 1, and host computer 2.

[0027] The detection assembly includes a signal acquisition module, which acquires ultrasonic detection data of a site under examination by transmitting and receiving ultrasonic waves between a plurality of ultrasonic probes and the site under examination, and transmits the ultrasonic detection data to a detection host 1 by forming it into an analog signal via 128 channels in the ultrasonic probe. The ultrasonic detection probe is a patch probe 3, one end of which is connected to a data cable 4, and is data connected to the detection host 1 via a plug.

[0028] The detection host 1 includes a control motherboard 1008, an ultrasonic hardware system mounted on the control motherboard 1008, a heatsink 1006 and a power converter 1007, and a housing 1003. The control motherboard 1008, heatsink 1006, and power converter 1007 are arranged inside the housing 1003, and the housing 1003 is connected by a mating mechanism, thereby forming a cavity inside the detection host 1.

[0029] An exposed switch 1001, which is the power switch for the detection host 1, is provided on one side of the housing 1003. A connection port 1002 is provided on one side of the housing 1003 for connecting to an external detection device to enable signal transmission.

[0030] Inside the detection host 1, there is a battery 1005 that supplies power to other powered devices within the monitoring device.

[0031] The heatsink 1006 is used to dissipate heat from the control motherboard 1008 and prevent it from overheating.

[0032] The power converter 1007 stores electrical energy in the battery 1005 by converting it into power during charging.

[0033] The ultrasonic hardware system includes a multiplexer module, an analog signal processing module, a beamforming module, and a host computer module.

[0034] The multiplexer module receives 128 channels of analog signals from three ultrasound probes transmitted from the signal acquisition module. It selects 128 channels of analog signals from one ultrasound probe, passes only the selected 128 channels from that probe, and transmits these 128 channels of analog signals to the analog signal processing module. The selection of the three ultrasound detection data is based on the actual observation needs of the examination site. The analog signal processing module receives 128 selected analog signals, performs low-noise amplification, noise reduction filtering, variable gain amplification, and analog-to-digital signal conversion on each channel's analog signal, and finally converts it into digitized 128-channel, 12-bit channel data which is then transmitted to the beamforming module. The parameters for a single-channel analog signal chain are as follows:

[0035] 1. The low-noise amplifier (LNA) in the receiving circuit supports gain adjustment of +12dB or +18dB.

[0036] 2. The variable gain amplifier (VGA) in the receiving circuit supports linear adjustment of the gain from 0dB to +30dB.

[0037] 3. The anti-aliasing filter (AAF) in the receiving circuit supports bandwidths of 9MHz, 10MHz, 15MHz, and 18MHz.

[0038] The receiving circuit's ADC resolution is 12 bits, and the sampling rate is 50 MHz.

[0039] The beamforming module receives digitized 128-channel, 12-bit channel data, performs delay compensation on each channel's channel data to align the phase of the compensated digitized 128-channel, 12-bit channel data based on the delay time calculated by the monitoring system, then combines the delay-compensated digitized 128-channel, 12-bit channel data into a single channel through addition, and performs IQ demodulation and low-pass filtering on the combined beam signal data to obtain baseband IQ data within a specific bandwidth range.

[0040] As shown in Figure 13, Assuming that data x1(t), x2(t)...x128(t) are input to 128 receiving channels at time t, and after delay addition, the corresponding path delay for each channel ch is calculated. τ ch (t) is calculated, and for each channel data, τ ch After performing delay compensation using (t), all data is added together to obtain the beamforming data. S(t) Forming,

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[0041] As shown in Figure 14, The beamforming signal S(t) is a modulated signal containing carriers. To facilitate subsequent processing, it is necessary to demodulate and perform low-pass filtering to convert it into a baseband signal with a center frequency of 0, while suppressing unwanted signals outside the design bandwidth. The signal is demodulated, that is, S(t) is given the complex demodulation coefficients. e -j×2×π×fc×t =cos(2×π×fc×t)-j×sin(2×π×fc×t)Multiply by , where fc is the demodulation frequency, and thereby obtain IQ demodulated data including the baseband signal. In actual operation, duplicate S(t) into two channels of signals, and each cos(2 × π × fc × t) and sin(2 × π × fc × t) Multiply by, I dem (t) = S(t) × cos(2 × π × fc × t) Q dem (t) = S(t) × -sin(2 × π × fc × t) Since the demodulated IQ data contains unwanted high-frequency components, it is necessary to pass each of the above IQ data through a low-pass filter (LPF) in order to obtain an IQ signal within the desired bandwidth. Assuming that the required signal bandwidth is B, the final IQ data can be obtained by setting the cutoff frequency of the low-pass filter function H(t) to B / 2. I(t)=I dem (t)ΦH(t) Q(t) = Q dem (t)ΦH(t) In the above equation, Φ represents the convolution operator, Image preprocessing, including envelope extraction and logarithmic compression, is performed on the baseband IQ data to obtain displayable image data. The IQ data obtained by demodulation filtering contains information about the phase and amplitude of the original beam data. However, in B-mode, the amplitude is required, so an envelope operation is performed on the IQ data to obtain the amplitude of the original beam data.

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[0042] The host computer 2 is signal-connected to the detection host 1 and is used to display related images and information.

[0043] The host computer 2 performs interactive control over the ultrasonic hardware system, specifically by controlling the multiplexer module to select the analog signal to be passed through, and by issuing commands to the ultrasonic hardware system to control the acquisition of signals by the signal acquisition module. The acquisition method involves the user controlling the activation of the scanning function of the three probes via the host computer 2. The host computer 2 issues commands to the ultrasound hardware system via WIFI. First, it controls the multiplexer module to select only probe 1, scans for S seconds, pauses for G seconds, and uploads the image of probe 1 to the host computer in real time. Next, it controls the multiplexer module via software to select only probe 2, scans for S seconds, pauses for G seconds, and uploads the image of probe 2 to the host computer 2 in real time. Finally, it controls the multiplexer module via software to select only probe 3, scans for S seconds, pauses for G seconds, and uploads the image of probe 3 to the host computer 2 in real time. After that, the host computer 2 controls the multiplexer module to switch back to probe 1, and so on. If the active time of the scanning function of the three probes exceeds T seconds, the software controls the monitoring system to stop scanning, and the host computer 2 acquires image data from each of the three probes.

[0044] A connecting plate 5 and a support plate 6 that supports the connecting plate 5 are provided on the upper surface of the detection host 1. One side of the connecting plate 5 is rotatably connected to the detection host 1 and connected to the host computer 2 by magnetic attraction.

[0045] Example 2: Example of use of a monitoring device for detecting thrombus formation The equipment used in this embodiment is the same as in Embodiment 1.

[0046] Research subject The study participants were patients who had been bedridden for extended periods (>72 hours) in the emergency and intensive care unit of Shanghai Sixth People's Hospital. The purpose and methods of this study were explained to the patients, their consent was obtained, and informed consent was signed.

[0047] The monitoring equipment was operated by a specialized ward physician or nurse who had received specialized ultrasound training and was capable of detecting the formation of blood clots early and in a timely manner.

[0048] Operating Procedure 1) Power on the detection host 1 of the monitoring device and connect detection host 1 and host computer 2 wirelessly.

[0049] 2) The patch probes of the monitoring device are placed on the skin surface corresponding to the femoral vein, popliteal vein, and intermuscular vein of the lower leg of the subject, respectively. The three patch probes are fixed to their respective positions with adhesive tape, and the ultrasound image on the host computer 2 is adjusted so that its gain and depth are optimal.

[0050] 3) To enable real-time dynamic monitoring of ultrasound images of the lower extremity veins, regardless of whether the subject is lying supine in a hospital bed or walking, and to predict thrombus formation early, the detection host 1 of the monitoring device is attached to the subject's waist.

[0051] 4) A specialist ward physician or nurse will detect the following signs of thrombus formation using ultrasound imaging of the lower extremity veins.

[0052] 2D images: Dialysis of vein diameter, irregularity of the vein wall, appearance of intraluminal echo, insufficient lumen closure after compression, <10% increase in vein diameter during Valsalva maneuver.

[0053] Color Doppler image: When the venous lumen is not completely filled with blood flow, the color enhancement phenomenon does not occur when the probe is compressed.

[0054] Spectral Doppler imaging: Blood flow velocity no longer changes with respiration, and the response to the Valsalva test disappears.

[0055] If any of the above signs are observed in the ultrasound image, the physician and nurse must promptly report to their supervisor and implement appropriate drug treatment.

[0056] The incidence of venous thrombosis in the left lower limb is 2 to 3 times higher than in the right lower limb.

[0057] In a statistical study of 1432 cases, the incidence of venous thrombosis was 69.3% in the left lower limb, 26.6% in the right lower limb, and 4.1% bilaterally. Therefore, the probe was first placed in the left lower limb to monitor for thrombosis.

[0058] The incidence of intermuscular vein thrombosis in the lower leg is higher than in the femoral vein and popliteal vein. However, the mortality rate due to thrombus formation in the femoral and popliteal veins is higher than in the intermuscular veins of the lower leg. Furthermore, the femoral and popliteal veins are more easily visualized on ultrasound. Therefore, three patch probes were placed on the skin surface corresponding to the femoral vein, popliteal vein, and intermuscular vein of the lower leg, respectively, to monitor for thrombus formation.

[0059] Image examples and interpretations Under 2D conditions: Under normal conditions, 1. the walls of the lower extremity veins are smooth and continuous, and the echogenicity within the lumen is good; 2. when compressed with a probe, the venous lumen closes; and 3. the venous diameter increases by ≥10% during the Valsalva maneuver.

[0060] In cases of thrombosis in the lower extremity veins, 1) the walls of the lower extremity veins become thicker and more irregular, exceeding 2 mm in thickness, and fine, floating, weak, hypoechoic, or hyperechoic echoes appear in the lumen; 2) the venous lumen does not close when compressed with a probe; and 3) the venous diameter increases by <10% during the Valsalva maneuver.

[0061] In Figure 8, A is a cross-section of a normal common femoral vein, and B is a longitudinal section of a normal femoral vein.

[0062] Under normal conditions, the walls of the lower extremity veins are smooth and continuous, with good echogenicity within the lumen. When compressed with a probe, the venous lumen closes, and the venous diameter increases by ≥10% during the Valsalva maneuver.

[0063] In Figure 9, A is a longitudinal section of the common femoral vein where the thrombus formed, and B is a cross-sectional section of the femoral vein where the thrombus formed.

[0064] In cases where a thrombus forms in the lower extremity veins, the vein walls thicken, solid echoes appear within the lumen, and when compressed with a probe, the venous lumen does not close, resulting in a <10% increase in vein diameter during the Valsalva maneuver.

[0065] Under color Doppler conditions: Under normal conditions, 1) the lumen of the lower extremity veins is well filled with blood flow, and 2) manual compression of the distal limb enhances the color Doppler signal of venous blood flow.

[0066] In situations where a thrombus forms in the lower extremity veins, 1) in the case of partial embolism, there is a filling defect in the lumen of the lower extremity vein, blood flow is not continuous, and only a thin blood flow signal is observed; in the case of complete embolism, there is no blood flow in the lower extremity vein; and 2) when the distal limb is manually compressed, the enhancement of the color Doppler signal of venous blood flow disappears or decreases.

[0067] In Figure 10, A is a color Doppler image of a normal popliteal vein, and B is a color Doppler image of a normal femoral vein. Under normal conditions, the lumen of the lower extremity veins is well filled with blood flow.

[0068] In Figure 11, A is a color Doppler image of a femoral vein with partial embolism, showing a filling defect in the vein lumen, inconsistent blood flow, and only a thin blood flow signal. B is a color Doppler image of a femoral vein with complete embolism, showing no blood flow in the lower extremity vein.

[0069] Under spectral Doppler conditions: Under normal conditions, 1) the spectrum of lower extremity veins, i.e., blood flow velocity, changes with respiration, and 2) in the Valsalva test, a retrograde spectrum of blood flow appears and does not last longer than 0.5 seconds.

[0070] In a situation where a thrombus forms in the lower extremity veins, 1) the spectrum of the lower extremity veins, i.e., the blood flow velocity, no longer changes with respiration, and 2) the response to the Valsalva test disappears.

[0071] In Figure 12, A is a spectral Doppler image of a normal femoral vein, and B is a spectral Doppler image of a femoral vein with a thrombus in the proximal side.

[0072] Under normal conditions, the spectral waveform of the lower extremity veins is affected by respiration, and its amplitude changes. If a thrombus forms proximal to a lower extremity vein, the spectral waveform of the lower extremity vein disappears with respiration.

[0073] The above description is merely a preferred embodiment of the present invention and does not limit the present invention in any way. The above preferred embodiment is disclosed in the present invention but does not limit the present invention. Those skilled in the art can modify or change to equivalent embodiments by utilizing the above disclosed technical content without departing from the scope of the technical means of the present invention. Any simple modifications, equivalent changes, and modifications made to the above embodiment in accordance with the technical idea of ​​the present invention without departing from the technical content of the present invention should all be included within the scope of the technical means of the present invention. [Explanation of symbols]

[0074] 1. Discovery Host 2 Host computer 3 Patch probes 4 Data Cables 5. Connecting plate 6 Support plate 1001 Power switch 1002 Connection Port 1003 Casing 1004 Protective Case 1005 Battery 1006 Heatsink 1007 Power Converter 1008 Motherboard

Claims

1. A monitoring system for detecting the formation of venous thrombosis in the lower extremities, Includes a signal acquisition module and an ultrasonic hardware system, The signal acquisition module acquires ultrasound detection data of the area under examination by transmitting and receiving ultrasound between multiple ultrasound probes and the area under examination, and transmits the ultrasound detection data to the ultrasound hardware system by forming it into an analog signal via 128 channels in the ultrasound probe. The ultrasonic hardware system includes a multiplexer module, an analog signal processing module, a beamforming module, and a host computer module. The multiplexer module receives 128 channels of analog signals output from multiple ultrasound probes transmitted from the signal acquisition module, selects 128 channels of analog signals from one ultrasound probe, passes only the selected 128 channels of analog signals from that probe, and transmits the 128 channels of analog signals to the analog signal processing module. The selection of the multiple ultrasound detection data is made based on the actual observation needs of the area being examined. The analog signal processing module receives the selected 128 channels of analog signals, performs low-noise amplification, noise reduction filtering, variable gain amplification, and analog-to-digital signal conversion on each channel's analog signal, and finally converts it into digitized 128-channel, 12-bit channel data, which is then transmitted to the beamforming module. The beamforming module receives digitized 128-channel, 12-bit channel data, performs delay compensation on each channel's channel data to align the phase of the compensated digitized 128-channel, 12-bit channel data based on the delay time calculated by the monitoring system, then combines the delay-compensated digitized 128-channel, 12-bit channel data into one channel's data through addition, performs IQ demodulation and low-pass filtering on the combined beam signal data to obtain baseband IQ data within a specific bandwidth range. Image preprocessing, including envelope extraction and logarithmic compression, is performed on the baseband IQ data to obtain displayable image data, and the processed image data is transmitted to the host computer module. The host computer module displays the processed digital signal on the host computer in the form of the image data. A monitoring system.

2. The host computer is a display, A monitoring system for detecting the formation of lower limb venous thrombosis according to feature 1.

3. The host computer module performs interactive control over the ultrasonic hardware system, specifically by controlling the multiplexer module to select the analog signal to be passed through. A monitoring system for detecting the formation of lower limb venous thrombosis according to feature 1.

4. The host computer module issues commands to the ultrasonic hardware system to control signal acquisition by the signal acquisition module, and the acquisition method involves the user controlling the activation of the scanning function of multiple probes via the host computer module. A monitoring system for detecting the formation of lower limb venous thrombosis according to feature 3.

5. The host computer module issues a command 1 to the ultrasound hardware system via Wi-Fi, causing the multiplexer module to select only probe 1, scan for S seconds, pause for G seconds, and upload the image of probe 1 to the host computer in real time. Next, it issues a command 2 to cause the multiplexer module to select only probe 2, scan for S seconds, pause for G seconds, and upload the image of probe 2 to the host computer in real time. Finally, it issues a command 3 to cause the multiplexer module to select only probe 3, scan for S seconds, pause for G seconds, and upload the image of probe 3 to the host computer in real time. After that, the host computer module controls the multiplexer module to switch back to probe 1, and so on. When the activation time of the scanning function of the three probes exceeds T seconds, the software controls the monitoring system to stop scanning, and the host computer module acquires image data from each of the three probes. A monitoring system for detecting the formation of lower limb venous thrombosis according to feature 1.

6. A monitoring device for detecting the formation of venous thrombosis in the lower extremities, The system includes a detection assembly, a detection host (1), and a host computer (2), The detection assembly includes the signal acquisition module described in claim 1, wherein the ultrasonic detection probe is a patch probe (3), the probe (3) having one end connected to a data cable (4) and data connected to the detection host (1) via a plug. The detection host (1) includes a control motherboard (1008), a heatsink (1006), a power converter (1007), and a housing (1003). The control motherboard (1008), the heatsink (1006), and the power converter (1007) are arranged inside the enclosure (1003). The control motherboard (1008) is equipped with the ultrasonic hardware system described in claim 1, and is responsible for analyzing and processing various data, controlling other electrical equipment within the monitoring device, and transmitting information. The host computer (2) is signal-connected to the detection host (1) and is used to display related images and information. monitoring equipment.

7. The housing (1003) is connected by a fitting method, thereby forming a cavity inside the detection host (1). An exposed switch (1001), which is the power switch for the detection host (1), is provided on one side of the housing (1003). A connection port (1002) is provided on one side of the housing (1003) for connecting to an external detection device to enable signal transmission. Inside the detection host (1), a battery (1005) is provided to supply power to other powered devices within the monitoring device. A monitoring device for detecting the formation of lower limb venous thrombosis according to feature 6.

8. The heat sink (1006) is used to dissipate heat from the control motherboard (8) and prevent it from overheating. A monitoring device for detecting the formation of lower limb venous thrombosis according to feature 6.

9. The power converter (1007) stores electrical energy in the battery (1005) by converting electrical energy into power during charging. A monitoring device for detecting the formation of lower limb venous thrombosis according to feature 6.

10. The upper surface of the detection host (1) is provided with a connecting plate (5) and a support plate (6) that supports the connecting plate (5). One side of the connecting plate (5) is rotatably connected to the detection host (1) and connected to the host computer (2) by magnetic attraction. A monitoring device for detecting the formation of lower limb venous thrombosis according to feature 6.

Images