Automatically adjustable low-temperature storage equipment

Abstract

This invention discloses an automatically adjustable low-temperature storage device comprising a sample storage chamber, a rotary storage mechanism, and a refrigeration cycle mechanism. The rotary storage mechanism is provided within the sample storage chamber, and the refrigeration cycle mechanism is provided within the sample storage chamber. The refrigeration cycle mechanism can circulate and refrigerate the sample storage chamber, and the rotary storage mechanism can store the samples. The beneficial effects of this invention include the ability to convert vaporized nitrogen gas into liquid nitrogen by the refrigeration cycle mechanism, thereby enabling the circulating use of liquid nitrogen and reducing liquid nitrogen consumption. Furthermore, this device can employ both liquid and electric power, enabling automatic temperature control of the sample storage chamber. The device is also convenient to remove and replace, energy-saving, environmentally friendly, and easy to clean.

Description

Technical Field

[0001] The present invention relates to the technical field of sample storage, and particularly to an automatically adjustable low-temperature storage device.

Background Art

[0002] In the field of biological sample storage, low-temperature access devices are used to store biological samples such as blood samples, vaccines, and bacterial and virus strains at low temperatures and to actively preserve the samples in a low-temperature state at all times.

[0003] In the rotary cage-type ultra-low temperature biological sample automated access system with the publication number CN202110990457.1 and the filing date of August 26, 2021, the sample storage method is a rotary drum type. However, in the process of accessing the sample, a mechanical arm is installed at the central axis position of the storage area to perform the sorting operation of the tubes. Since the storage area is in an ultra-low temperature environment, the electrical components of the mechanical arm are likely to be damaged when in the ultra-low temperature environment for a long time, which is likely to affect accessing the sample. In addition, the current cost of liquid nitrogen used is high, and it cannot be recycled, and refrigeration cannot be performed in case of a power outage. Therefore, the inventor designed an automatically adjustable low-temperature storage device.

Summary of the Invention

Problems to be Solved by the Invention

[0004] The purpose of this section is to outline some aspects of the embodiments of the present invention and briefly describe some preferred embodiments. In this section, the abstract of the present application, and the title of the invention, simplification or omission may be made to avoid the purpose of this section, the abstract, and the title of the invention from being unclear. Such simplification or omission does not limit the scope of the present invention.

[0005] In view of the problems existing in the above or the prior art, the present invention is proposed.

[0006] Therefore, the objective of this invention is to provide an automatically adjustable low-temperature storage device that allows the scraping equipment to be installed within the operating area by placing the operating area outside the storage chamber, thereby avoiding the mechanical arm being in a low-temperature environment for a long period of time, and by employing a Stirling refrigeration mechanism, liquid nitrogen can be circulated and liquefied, thereby avoiding the waste of liquid nitrogen and significantly reducing the cost of using liquid nitrogen. [Means for solving the problem]

[0007] To solve the above technical problems, the present invention provides an automatically adjustable low-temperature storage device comprising a sample storage chamber, a rotary storage mechanism, and a refrigeration cycle mechanism, wherein a rotatable rotary storage mechanism is provided within the sample storage chamber, a refrigeration cycle mechanism is provided within the sample storage chamber, the refrigeration cycle mechanism can circulate and refrigerate the sample storage chamber, and the rotary storage mechanism can store the samples.

[0008] A preferred embodiment of the automatically adjustable low-temperature storage device of the present invention includes a refrigeration cycle mechanism comprising a cooling chamber and a refrigerator, wherein the cooling chamber is located inside the sample storage chamber and inside the rotary storage mechanism, the refrigerator is located above the sample storage chamber, the upper end of the cooling chamber is in communication with the refrigerator, and the refrigerator can receive vaporized nitrogen gas in the cooling chamber, liquefy the nitrogen gas, and return it to the cooling chamber.

[0009] A preferred configuration of the automatically adjustable cryogenic storage device of this invention is such that the cooling chamber is a liquid nitrogen tank fixedly installed within the sample storage chamber, and a liquid addition system is installed within the liquid nitrogen tank.

[0010] A preferred embodiment of the automatically adjustable low-temperature storage equipment of the present invention includes a refrigeration module, a first pipe, and a second pipe, the upper ends of the first and second pipes being connected to the refrigeration module, the lower end of the first pipe being installed in the upper part of the cooling chamber, and the lower end of the second pipe being installed in the lower part of the cooling chamber.

[0011] In a preferred configuration of the automatically adjustable low-temperature storage device of the present invention, a control mechanism is further provided above the sample storage chamber, and the control mechanism can freeze the cooling chamber.

[0012] A preferred embodiment of the automatically adjustable cryogenic storage device of the present invention further includes a pressure relief assembly in the cooling chamber, which can release pressure and exhaust the contents of the cooling chamber.

[0013] In a preferred configuration of the automatically adjustable low-temperature storage device of the present invention, the rotary storage mechanism is capable of rotating the cooling chamber, the extended end of the refrigerator is installed inside the cooling chamber, a cold conductive liquid is installed inside the cooling chamber, the cooling chamber is a central rotation axis, and its upper end is in communication with the refrigeration cycle mechanism.

[0014] A preferred embodiment of the automatically adjustable low-temperature storage device of this invention is a rotary storage mechanism that can rotate the cooling chamber, the cooling chamber having a central rotating shaft integrated structure, and liquid nitrogen being installed inside the cooling chamber.

[0015] A preferred embodiment of the automatically adjustable cryogenic storage device of the present invention includes a rotary storage mechanism comprising a drive member and a rotary storage assembly, wherein the drive member is provided in the sample storage chamber, the rotary storage assembly is provided inside the sample storage chamber, the drive member drives the rotary storage assembly to rotate, and the rotary storage assembly can store baskets.

[0016] A preferred embodiment of the automatically adjustable cryogenic storage device of the present invention includes a rotary storage assembly comprising a longitudinal storage frame, wherein multiple sets of longitudinal storage frames are arranged circumferentially as storage discs, a gear disc is mounted on the upper end of the storage disc, and a drive member can be driven to rotate the gear disc.

[0017] A preferred embodiment of the automatically adjustable cryogenic storage device of the present invention is one in which a drive member is installed at the upper end of the sample storage chamber, a gear disc is installed at the upper end of the cooling chamber, the gear disc is installed on one side of the drive member, the drive member can be driven to rotate the gear disc and the cooling chamber, a rotating storage assembly is installed inside the sample storage chamber, and the cooling chamber can rotate the rotating storage assembly.

[0018] In a preferred embodiment of the automatically adjustable cryogenic storage device of the present invention, the rotating storage assembly includes a vertical storage frame, where multiple sets of vertical storage frames are arranged circumferentially as storage disks, a rotating disk is placed on the upper end of the storage disks, the rotating disk is connected to a cooling chamber, and the rotation of the cooling chamber causes the rotating disk and the storage disk to rotate.

[0019] A preferred configuration of the automatically adjustable low-temperature storage device of this invention is one in which a vertical passage mechanism is installed in the sample storage chamber, and the vertical passage mechanism allows access to the samples in the rotating storage mechanism.

[0020] A preferred embodiment of the automatically adjustable low-temperature storage device of the present invention includes a vertical passage mechanism comprising a vertical passage, a passage door drive member, a transmission member, and a passage door, wherein a vertical passage is provided in a sample storage chamber, a passage door is installed within the vertical passage, the passage door is connected to the passage door drive member at the upper end via a transmission member, and the passage door drive member drives the passage door via the transmission member to open and close the vertical passage.

[0021] A preferred embodiment of the automatically adjustable low-temperature storage device of the present invention further includes a control box, which is located on the side of the sample storage chamber and can control the temperature inside the sample storage chamber.

[0022] In a preferred configuration of the automatically adjustable low-temperature storage device of the present invention, a power distribution system, a condenser, and control members are installed in a control box, the power distribution system provides power to the device, and the condenser and control members can perform temperature control over the sample storage chamber.

[0023] The beneficial effects of the present invention are as follows. The present invention can convert nitrogen gas vaporized by a refrigeration cycle mechanism into liquid nitrogen, thereby realizing the recycling of liquid nitrogen and reducing the consumption of liquid nitrogen. In addition, this device can adopt both liquid and electric power, and can automatically adjust the temperature of the sample storage chamber. This device is convenient for removal and replacement, energy-saving, environmentally friendly, and easy to clean.

Brief Description of the Drawings

[0024] To more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings required for describing the embodiments will be briefly described below. The drawings in the following description are only some embodiments of the present invention, and it is obvious that those skilled in the art can obtain other drawings based on these drawings without creative efforts. [Figure 1] It is an overall schematic diagram of Embodiment 1 of an automatically adjustable low-temperature storage device. [Figure 2] It is an internal structure diagram of Embodiment 1 of an automatically adjustable low-temperature storage device. [Figure 3] It is an internal cross-sectional view of Embodiment 1 of an automatically adjustable low-temperature storage device. [Figure 4] It is a schematic diagram of the rotating storage mechanism of Embodiment 1 of an automatically adjustable low-temperature storage device. [Figure 5] It is a partially enlarged view of the refrigerator in Embodiment 1 of an automatically adjustable low-temperature storage device. [Figure 6] It is an overall semi-sectional schematic diagram of Embodiment 1 of an automatically adjustable low-temperature storage device. [Figure 7] It is a schematic diagram of the vertical passage mechanism of an automatically adjustable low-temperature storage device. [Figure 8] It is a schematic diagram of Embodiment 2 of an automatically adjustable low-temperature storage device. [Figure 9] It is a schematic diagram of Embodiment 3 of an automatically adjustable low-temperature storage device. [Figure 10] It is an overall semi-sectional schematic diagram of Embodiment 3 of an automatically adjustable low-temperature storage device. [Modes for carrying out the invention]

[0025] To further clarify the above-mentioned objectives, features, and advantages of the present invention, specific embodiments of the present invention will be described in detail below with reference to the drawings.

[0026] In order to fully understand this invention, many specific details will be described below. However, this invention can also be implemented in ways different from those described herein, and those skilled in the art can similarly popularize it without departing from the spirit of the invention. Therefore, this invention is not limited to the specific embodiments disclosed below.

[0027] Next, the term "one embodiment" or "embodiment" as used herein refers to a specific feature, structure, or characteristic that may be included in at least one embodiment of the present invention. The phrase "in one embodiment" appearing elsewhere in this specification does not refer to the same embodiment, nor does it refer to an embodiment that is independently or selectively opposed to other embodiments.

[0028] Example 1 Referring to Figures 1-7, the first embodiment of the present invention provides an automatically adjustable low-temperature storage device comprising a sample storage chamber 1, a rotary storage mechanism 2, and a refrigeration cycle mechanism 3. The rotary storage mechanism 2 is provided within the sample storage chamber 1 and rotates within the sample storage chamber 1 to store baskets. Samples are stored in the baskets, and the refrigeration cycle mechanism 3 can freeze the sample storage chamber 1.

[0029] Specifically, regarding the sample storage chamber 1, the rotary storage mechanism 2, and the refrigeration cycle mechanism 3, the rotary storage mechanism 2 is provided within the sample storage chamber 1, the refrigeration cycle mechanism 3 is provided within the sample storage chamber 1, the refrigeration cycle mechanism 3 can circulate and cool the sample storage chamber 1, and the rotary storage mechanism 2 can store samples.

[0030] Preferably, the refrigeration cycle mechanism 3 is a Stirling refrigeration system.

[0031] Preferably, the refrigeration cycle mechanism 3 can circulate and refrigerate the sample storage chamber 1, allowing the inside of the sample storage chamber 1 to remain refrigerated even in the event of a power outage, thus avoiding damage to the samples due to the power outage.

[0032] Furthermore, the refrigeration cycle mechanism 3 includes a cooling chamber 31 and a refrigerator 32. The cooling chamber 31 is located inside the sample storage chamber 1 and inside the rotary storage mechanism 2. The refrigerator 32 is located above the sample storage chamber 1. The upper end of the cooling chamber 31 communicates with the refrigerator 32. The refrigerator 32 can receive the nitrogen gas vaporized in the cooling chamber 31, liquefy the nitrogen gas, and return it to the cooling chamber 31.

[0033] Furthermore, the cooling chamber 31 is a liquid nitrogen tank and is permanently installed within the sample storage chamber 1, and a liquid addition system is installed inside the liquid nitrogen tank.

[0034] Preferably, the initial liquid addition into the cooling chamber 31 can be performed by a liquid addition system.

[0035] Preferably, a fixed amount of liquid nitrogen is provided in the liquid nitrogen tank, eliminating the need to add liquid along the way.

[0036] Preferably, the cooling chamber 31 is located in the middle of the rotary storage mechanism 2, allowing for easy low-temperature refrigeration of the sample cartridges and sample tubes in the rotary storage mechanism 2.

[0037] Preferably, the liquid nitrogen in the cooling chamber 31 undergoes natural vaporization, the vaporized nitrogen gas enters the upper end, and the refrigerator 32 liquefies the vaporized nitrogen gas and flows it back into the bottom end of the cooling chamber 31, thereby circulating refrigeration, and enabling circulating refrigeration even in the event of a power outage.

[0038] Furthermore, the refrigerator 32 includes a refrigeration module 321, a first pipe 322, and a second pipe 323. The upper ends of the first pipe 322 and the second pipe 323 are connected to the refrigeration module 321, the lower end of the first pipe 322 is located in the upper part of the cooling chamber 31, and the lower end of the second pipe 323 is located in the lower part of the cooling chamber 31.

[0039] Preferably, nitrogen gas can be drawn into the refrigeration module 321 via the first pipe 322, cooled, and liquefied. The liquefied liquid nitrogen can then reach the bottom of the cooling chamber 31 via the second pipe 323 and be vaporized again from bottom to top, allowing the lateral rotating storage mechanism 2 to be frozen at a low temperature. This circulates and cools the vaporized nitrogen gas, resulting in circulating refrigeration using liquid nitrogen and nitrogen gas.

[0040] Preferably, liquid nitrogen can achieve zero loss and enable an automatically temperature-controlled technology from +5°C to -200°C.

[0041] Preferably, in this embodiment, there is no need to use a refrigerant medium, making it effectively environmentally friendly, and the device is 50% more energy-efficient than conventional refrigerators.

[0042] Furthermore, a control mechanism 4 is provided above the sample storage chamber 1, and the control mechanism 4 can freeze the cooling chamber 31.

[0043] Preferably, the control mechanism 4 can employ a method such as solar energy or a portable power source, which can effectively prevent damage to the samples inside the sample storage chamber 1 in the event of a power outage.

[0044] Furthermore, the cooling chamber 31 is further provided with a pressure release assembly 5, which can release pressure and exhaust air from inside the cooling chamber 31.

[0045] Preferably, the pressure relief assembly 5 can be configured to evacuate when liquid nitrogen is first added, and can also be configured to evacuate actively when the internal pressure is high.

[0046] Furthermore, the rotary storage mechanism 2 includes a drive member 21 and a rotary storage assembly 22. The drive member 21 is provided in the sample storage chamber 1, and the rotary storage assembly 22 is provided inside the sample storage chamber 1. The drive member 21 can drive the rotary storage assembly 22 to rotate, and the rotary storage assembly 22 can store baskets, and sample cartridges can be stored in the baskets.

[0047] Preferably, the drive member 21 includes a motor and a gear drive shaft, the motor drives the gear drive shaft to rotate, the gear drive shaft is connected to and meshes with the gear disc 223, thereby rotating the gear disc 223, i.e., the storage disc 222.

[0048] Furthermore, the rotary storage assembly 22 includes a vertical storage frame 221, which consists of multiple sets of vertical storage frames 221 arranged circumferentially as storage discs 222, with a gear disc 223 provided at the upper end of the storage discs 222, and a drive member 21 can be driven to rotate the gear disc 223.

[0049] Preferably, the vertical storage frame 221 is a basket that can store sample cartridges.

[0050] Furthermore, a vertical passage mechanism 6 is installed in the sample storage chamber 1, allowing access to the samples in the rotating storage mechanism 2 via the vertical passage mechanism 6.

[0051] Preferably, the vertical passage mechanism 6 is openable and closable. When open, the external scraping mechanism can scrape sample cartridges on the vertical storage frame 221. When closed, the external scraping mechanism cannot enter the sample storage chamber 1, thus preventing damage to the external scraping mechanism and tube sorting mechanism due to the cryogenic environment inside the sample storage chamber 1.

[0052] Furthermore, the vertical passage mechanism 6 includes a vertical passage, a passage door driving member 61, a transmission member 62, and a passage door 63. A vertical passage is opened in the sample storage room 1, a passage door 63 is provided within the vertical passage, the passage door 63 is connected to the passage door driving member 61 at its upper end via the transmission member 62, and the passage door driving member 61 drives the passage door 63 via the transmission member 62 to open and close the vertical passage.

[0053] Furthermore, the system includes a control box 7 located on the side of the sample storage chamber 1, which can control the temperature inside the sample storage chamber 1.

[0054] Furthermore, a power distribution system 71, a condenser 72, and a control member 73 are installed inside the control box 7. The power distribution system 71 can supply power to the equipment, and the condenser 72 and control member 73 can control the temperature of the sample storage chamber 1.

[0055] As described above, this invention provides a multi-functional ultra-low temperature refrigerator that can use both liquid and electric power, resulting in superior cold storage and preservation of samples. By replenishing liquid nitrogen, it enables long-term use, reduces the cost of using liquid nitrogen, and achieves an automatically adjustable temperature range of +5°C to -200°C. It does not require a refrigerant medium, making it more energy-efficient, environmentally friendly, and reducing operating costs.

[0056] Example 2 Referring to Figure 8, a second embodiment of the present invention, based on Embodiment 1, includes an automatically adjustable low-temperature storage device comprising a sample storage chamber 1, a rotary storage mechanism 2, and a refrigeration cycle mechanism 3. The rotary storage mechanism 2 is installed inside the sample storage chamber 1 and can rotate within the sample storage chamber 1 to store baskets, samples are stored in the baskets, and the refrigeration cycle mechanism 3 can freeze the sample storage chamber 1.

[0057] Specifically, the system includes a sample storage chamber 1, a rotary storage mechanism 2, and a refrigeration cycle mechanism 3. The rotary storage mechanism 2 is rotatable within the sample storage chamber 1, the refrigeration cycle mechanism 3 is located within the sample storage chamber 1, the refrigeration cycle mechanism 3 can circulate and refrigerate the sample storage chamber 1, and the rotary storage mechanism 2 can store samples.

[0058] Preferably, the refrigeration cycle mechanism 3 can circulate and refrigerate the sample storage chamber 1, allowing the inside of the sample storage chamber 1 to remain refrigerated even in the event of a power outage, thus avoiding damage to the samples due to the power outage.

[0059] Preferably, the refrigeration cycle mechanism 3 is a Stirling refrigeration system.

[0060] Furthermore, the refrigeration cycle mechanism 3 includes a cooling chamber 31 and a refrigerator 32. The cooling chamber 31 is located inside the sample storage chamber 1 and inside the rotary storage mechanism 2. The refrigerator 32 is located above the sample storage chamber 1. The upper end of the cooling chamber 31 communicates with the refrigerator 32. The refrigerator 32 can receive the nitrogen gas vaporized in the cooling chamber 31, liquefy the nitrogen gas, and return it to the cooling chamber 31.

[0061] Preferably, the liquid nitrogen in the cooling chamber 31 undergoes natural vaporization, the vaporized nitrogen gas enters the upper end, and the refrigerator 32 liquefies the vaporized nitrogen gas and flows it back into the bottom end of the cooling chamber 31, thereby performing circulating refrigeration, which can be maintained even when the power is turned off.

[0062] Furthermore, the rotary storage mechanism 2 can rotate the cooling chamber 31, the extended end of the refrigerator 32 is installed inside the cooling chamber 31, a cold conductive liquid is installed inside the cooling chamber 31, the cooling chamber 31 is a central rotation axis and its upper end is in communication with the refrigeration cycle mechanism 3.

[0063] Preferably, the upper end of the cooling chamber 31 rotates around the refrigerator 32.

[0064] Preferably, in this embodiment, the cooling chamber 31 is connected to the gear disk 223, and the cooling chamber 31 rotates the storage disk 222, thereby causing the vertical storage frame 221 to rotate circumferentially.

[0065] Preferably, the cooling chamber 31 is located in the middle of the rotary storage mechanism 2, allowing for easy low-temperature refrigeration of the sample cartridges and sample tubes in the rotary storage mechanism 2.

[0066] Preferably, a cooling conductive liquid is installed in the cooling chamber 31, and the cooling conductive liquid can be used to assist in the refrigeration process.

[0067] Furthermore, the rotary storage mechanism 2 includes a drive member 21 and a rotary storage assembly 22. The drive member 21 is provided in the sample storage chamber 1, and the rotary storage assembly 22 is provided inside the sample storage chamber 1. The drive member 21 can drive the rotary storage assembly 22 to rotate, and the rotary storage assembly 22 can store baskets, and sample cartridges can be stored in the baskets.

[0068] Preferably, the drive member 21 includes a motor and a gear drive shaft, the motor drives the gear drive shaft to rotate, the gear drive shaft is connected in mesh with the gear disc 223, thereby rotating the gear disc 223, i.e., the storage disc 222.

[0069] Furthermore, the rotary storage assembly 22 includes a vertical storage frame 221, which consists of multiple sets of vertical storage frames 221 arranged circumferentially as storage discs 222, with a gear disc 223 provided at the upper end of the storage discs 222, and a drive member 21 can be driven to rotate the gear disc 223.

[0070] Preferably, the vertical storage frame 221 is a basket that can store sample cartridges.

[0071] Furthermore, a vertical passage mechanism 6 is installed in the sample storage chamber 1, allowing access to the samples in the rotating storage mechanism 2 via the vertical passage mechanism 6.

[0072] Preferably, the vertical passage mechanism 6 is openable and closable. When open, the external scraping mechanism can scrape sample cartridges from the vertical storage frame 221. When closed, the external scraping mechanism cannot enter the sample storage chamber 1, thus preventing damage to the external scraping mechanism and tube sorting mechanism due to the cryogenic environment inside the sample storage chamber 1.

[0073] Furthermore, the vertical passage mechanism 6 includes a vertical passage, a passage door driving member 61, a transmission member 62, and a passage door 63. A vertical passage is opened in the sample storage room 1, a passage door 63 is provided within the vertical passage, the passage door 63 is connected to the passage door driving member 61 at its upper end via the transmission member 62, and the passage door driving member 61 drives the passage door 63 via the transmission member 62 to open and close the vertical passage.

[0074] Furthermore, the system includes a control box 7 located on the side of the sample storage chamber 1, which can control the temperature inside the sample storage chamber 1.

[0075] Furthermore, a power distribution system 71, a condenser 72, and a control member 73 are installed inside the control box 7. The power distribution system 71 distributes power to the equipment, and the condenser 72 and control member 73 can perform temperature control for the sample storage chamber 1.

[0076] Preferably, the cooling chamber 31 is a central rotating shaft, a certain amount of liquid nitrogen is placed into the central rotating shaft at once and sealed, the Stirling machine is started, the liquid nitrogen conducts through the cooling chamber 31 and naturally vaporizes, rising to the top, where it is cooled and liquefied by the Stirling refrigerator 32, the liquid is automatically stored at the bottom, and the machine is operated automatically and repeatedly to achieve a uniform cold conduction refrigeration effect, and a high-pressure Stirling cold head and a high-pressure stainless steel shaft are used to form a high-pressure chamber that does not require pressure relief.

[0077] The liquid, whose liquefaction capacity is enhanced by the high-pressure boiling point difference, settles rapidly and cools evenly. With a single liquid addition and final use, regardless of whether the power is on or storage is performed, the vaporized gas, such as liquid nitrogen, self-compresses within the chamber, ensuring safe and unaffected long-term storage. It also features ease of replacement and upgrade, as well as ease of cleaning and disinfection.

[0078] As described above, this invention allows the cooling chamber 31 to be rotated by the rotating storage mechanism 2, vaporizing the liquid in the cooling chamber 31 and causing it to rise into the refrigerator 32. The refrigerator 32 converts the vaporized nitrogen gas into liquid nitrogen and flows it into the bottom of the cooling chamber 31, thereby circulating and liquefying the vaporized nitrogen gas. This circulates the liquid nitrogen for refrigeration, and a cooling conductive liquid is placed in the cooling chamber 31, further cooling the liquid nitrogen. This improves the cooling effect, enables a single liquid addition and final use, and significantly reduces the cost of using liquid nitrogen.

[0079] Example 3 Referring to Figures 9 and 10, a third embodiment of the present invention, based on Embodiment 1, includes an automatically adjustable low-temperature storage device comprising a sample storage chamber 1, a rotary storage mechanism 2, and a refrigeration cycle mechanism 3. The rotary storage mechanism 2 is installed in the sample storage chamber 1, which rotates within the sample storage chamber 1 to store baskets, samples are stored in the baskets, and the refrigeration cycle mechanism 3 can freeze the sample storage chamber 1.

[0080] Specifically, the system includes a sample storage chamber 1, a rotary storage mechanism 2, and a refrigeration cycle mechanism 3. The rotary storage mechanism 2 is rotatable within the sample storage chamber 1, the refrigeration cycle mechanism 3 is located within the sample storage chamber 1, the refrigeration cycle mechanism 3 can circulate and refrigerate the sample storage chamber 1, and the rotary storage mechanism 2 can store samples.

[0081] Preferably, the refrigeration cycle mechanism 3 is a Stirling refrigeration system.

[0082] Preferably, the refrigeration cycle mechanism 3 can circulate and refrigerate the sample storage chamber 1, allowing the inside of the sample storage chamber 1 to remain refrigerated even in the event of a power outage, thus avoiding damage to the samples due to the power outage.

[0083] Furthermore, the refrigeration cycle mechanism 3 includes a cooling chamber 31 and a refrigerator 32. The cooling chamber 31 is located inside the sample storage chamber 1 and inside the rotary storage mechanism 2. The refrigerator 32 is located above the sample storage chamber 1. The upper end of the cooling chamber 31 communicates with the refrigerator 32, and the refrigerator 32 can receive the nitrogen gas vaporized in the cooling chamber 31, liquefy the nitrogen gas, and return it to the cooling chamber 31.

[0084] Furthermore, the rotating storage mechanism 2 rotates the cooling chamber 31, which has a central rotating shaft integrated structure and contains liquid nitrogen.

[0085] Preferably, in this embodiment, the cooling chamber 31 has a central rotating shaft integrated structure, the rotating shaft is hollow, and a certain amount of liquid nitrogen is injected at once to seal it. Furthermore, the central rotation axis can rotate from an angle of 0-190°, and of course, it can be designed for a 360-degree rotation angle, structure, liquid addition, and assembly. Both ends of the thick-walled hollow stainless steel tube are processed according to the requirements of the rotation axis, and a clamping method can be used for the sterling and the axis.

[0086] First, the rotating shaft of the cooling chamber 31 is inserted vertically into liquid nitrogen for cooling, and liquid is added. Then, the Stirling refrigerator 32 and the shaft are connected with clamps, and debugging is completed. The entire completed machine can then be stored at room temperature. This is an automatically adjustable technology ranging from +5°C to -200°C.

[0087] In addition, 1) It is a Stirling liquid-gas integrated cold conduction rotating shaft. A fixed amount of liquid nitrogen is added to the rotating shaft at once and sealed, and the Stirling engine refrigerator 32 is started. The liquid nitrogen conducted to the rotating shaft vaporizes and rises to the top, where it is cooled and liquefied by the Stirling engine refrigerator 32. The liquid is then automatically stored at the bottom, and the automatic operation is repeated to achieve a uniform cold conduction refrigeration effect. 2) A high-pressure chamber is formed using a high-pressure Stirling cold head and a high-pressure stainless steel shaft, eliminating the need to release pressure. 3) The high pressure and boiling point difference enhance the liquefaction capacity of the liquid, causing it to sink rapidly and cool uniformly. 4) After a single liquid addition and final use, regardless of whether the power is turned on or the device is stored, the vaporized gas, such as liquid nitrogen, self-compresses within the chamber and does not affect safe long-term storage. 5) Very easy to replace / upgrade, and easy to clean / disinfect.

[0088] Furthermore, a drive member 21 is provided at the upper end of the sample storage chamber 1, and a gear disc 223 is provided at the upper end of the cooling chamber 31. The gear disc 223 is provided on one side of the drive member 21, and the drive member 21 can drive the gear disc 223 and the cooling chamber 31 to rotate. A rotating storage assembly 22 is provided inside the sample storage chamber 1, and the cooling chamber 31 can rotate the rotating storage assembly 22.

[0089] Preferably, the drive member 21 employs a motor and a transmission gear, and the transmission gear meshes with the gear disc 223 to rotate the cooling chamber 31, which in turn rotates the rotating storage assembly 22.

[0090] Preferably, the upper end of the cooling chamber 31 penetrates the sample storage chamber 1 and communicates with the refrigerator 32, and the refrigerator 32 and the cooling chamber 31 can be fastened together in a clamping manner, that is, when the cooling chamber 31 rotates, the refrigerator 32 does not rotate in conjunction with it.

[0091] Preferably, the cooling chamber 31 is located in the middle of the rotary storage mechanism 2, allowing for easy low-temperature refrigeration of the sample cartridges and sample tubes in the rotary storage mechanism 2.

[0092] Preferably, the liquid nitrogen in the cooling chamber 31 undergoes natural vaporization, the vaporized nitrogen gas enters the upper end, and the refrigerator 32 liquefies the vaporized nitrogen gas and flows it back into the bottom end of the cooling chamber 31, thereby performing circulating refrigeration, which can be maintained even when the power is turned off.

[0093] Preferably, in this embodiment, there is no need to use a refrigerant medium, making it environmentally friendly, saving liquid nitrogen, and reducing costs.

[0094] Furthermore, the rotating storage assembly 22 includes a vertical storage frame 221, which is arranged around the circumference as a storage disk 222, with a rotating disk 225 mounted on the upper end of the storage disk 222, and the rotating disk 225 is connected to a cooling chamber 31, so that the rotation of the cooling chamber 31 can rotate the rotating disk 225 and the storage disk 222.

[0095] Furthermore, a vertical passage mechanism 6 is installed in the sample storage chamber 1, allowing access to the samples in the rotating storage mechanism 2 via the vertical passage mechanism 6.

[0096] Preferably, the vertical passage mechanism 6 is openable and closable. When open, the external scraping mechanism can scrape sample cartridges from the vertical storage frame 221. When closed, the external scraping mechanism cannot enter the sample storage chamber 1, thus preventing damage to the external scraping mechanism and tube sorting mechanism due to the cryogenic environment inside the sample storage chamber 1.

[0097] Furthermore, the vertical passage mechanism 6 includes a vertical passage, a passage door driving member 61, a transmission member 62, and a passage door 63. A vertical passage is opened in the sample storage room 1, a passage door 63 is provided within the vertical passage, the passage door 63 is connected to the passage door driving member 61 at its upper end via the transmission member 62, and the passage door driving member 61 drives the passage door 63 via the transmission member 62 to open and close the vertical passage.

[0098] Furthermore, the system includes a control box 7 located on the side of the sample storage chamber 1, which can control the temperature inside the sample storage chamber 1.

[0099] Furthermore, a power distribution system 71, a condenser 72, and a control member 73 are installed inside the control box 7. The power distribution system 71 distributes power to the equipment, and the condenser 72 and control member 73 can perform temperature control for the sample storage chamber 1.

[0100] As described above, by employing a Stirling refrigerator 32 and a cooling chamber 31 integrated with a central rotating shaft, this invention reduces liquid nitrogen consumption, lowers long-term operating costs, is easy to remove and replace, facilitates cleaning and disinfection, is more energy-efficient and environmentally friendly, reduces operating costs, and, with a single liquid addition and final use, regardless of whether the power is on or off, the liquid nitrogen vaporized by the Stirling refrigerator 32 is liquefied, achieving circulating liquid nitrogen refrigeration, eliminating the need for a refrigerant medium, making it more environmentally friendly, and enabling an automatically adjustable temperature range of +5°C to -200°C in the sample storage chamber 1, thus significantly saving on liquid nitrogen costs.

[0101] Importantly, it should be noted that the configurations and arrangements of the present invention shown in several different exemplary embodiments are for illustrative purposes only. Although only a few embodiments are described in detail in this disclosure, anyone referring to this disclosure should readily understand that many modifications are possible (e.g., changes in the size, scale, structure, shape, and proportion of various elements, as well as parameter values ​​(e.g., temperature, pressure, etc.), mounting arrangement, use of materials, color, and orientation) without substantially departing from the novel teachings and merits of the subject matter described herein. For example, elements shown as being formed integrally may consist of multiple parts or elements, the positions of elements may be reversed or otherwise altered, and the characteristics, number, or position of discrete elements may be modified or changed. Accordingly, all such modifications are included within the scope of the present invention. The order or sequence of steps in any process or method may be changed or rearranged according to alternative embodiments. In the claims, any “apparatus + function” clause is intended to cover structures that perform the function described herein, and the structures are not only equivalent but also equivalent structures. Within the scope of the present invention, other substitutions, modifications, changes, and omissions are possible in the design, operation, and arrangement of the exemplary embodiments. Therefore, the present invention is not limited to specific embodiments and can be extended to various modifications that fall within the scope of the utility model registration claims.

[0102] Furthermore, in order to simplify the description of exemplary embodiments, it is not necessary to describe all features of actual embodiments (i.e., features not related to the best mode considered for carrying out the present invention, or features not related to realizing the present invention).

[0103] It should be understood that in the development process of any actual embodiment, for example in any project or design item, a large number of specific embodiments can be determined. While such development efforts can be complex and time-consuming, for the average engineer who will benefit from this disclosure, such development efforts do not require much experimentation and are normal work in design, manufacturing, and production.

[0104] The above embodiments are merely for illustrative purposes and are not limiting. Although the present invention has been described in detail with reference to preferred embodiments, those skilled in the art should understand that modifications or equivalent substitutions can be made to the present invention without departing from the spirit and scope of the present invention, and that all such modifications should be included within the scope of the utility model claims of the present invention. [Explanation of Symbols]

[0105] 1. Sample storage room, 2 Rotary storage mechanism, 3. Refrigeration cycle mechanism, 31 Cooling room, 32 Refrigeration units, 321 refrigeration module, 322 First piping, 323 Second piping, 4. Control mechanism, 5. Pressure relief assembly, 21 Drive member, 22 Rotary Storage Assembly, 221 Vertical storage frame, 222 storage disks, 223 Gear Disc, 225 RPM disc, 6. Vertical passage mechanism, 61 Passageway door drive member, 62 Transmission members, 63 aisle door, 7. Control box, 71 Power distribution system, 72 condenser, 73 Control Member

Claims

1. Automatically adjustable low-temperature storage equipment, It includes a sample storage chamber (1), a rotary storage mechanism (2), and a refrigeration cycle mechanism (3), A rotatable rotating storage mechanism (2) is provided inside the sample storage chamber (1). The sample storage chamber (1) is provided with a refrigeration cycle mechanism (3). The refrigeration cycle mechanism (3) can circulate and refrigerate the sample storage chamber (1). The rotating storage mechanism (2) can store samples. An automatically adjustable low-temperature storage device characterized by the following features.

2. The refrigeration cycle mechanism (3) includes a cooling chamber (31) and a refrigerator (32), The cooling chamber (31) is provided inside the sample storage chamber (1) and inside the rotating storage mechanism (2), The refrigerator (32) is located above the sample storage chamber (1). The upper end of the cooling chamber (31) is in communication with the refrigerator (32), The refrigerator (32) can receive the nitrogen gas vaporized in the cooling chamber (31) and liquefy the nitrogen gas and return it to the cooling chamber (31). The automatically adjustable low-temperature storage device according to feature 1.

3. The cooling chamber (31) is a liquid nitrogen tank and is permanently installed within the sample storage chamber (1), and a liquid addition system is installed within the liquid nitrogen tank. The automatically adjustable low-temperature storage device according to feature 2.

4. The aforementioned refrigerator (32) includes a refrigeration module (321), a first pipe (322), and a second pipe (323). The upper ends of the first pipe (322) and the second pipe (323) are connected to the refrigeration module (321). The lower end of the first pipe (322) is located at the upper position of the cooling chamber (31), The lower end of the second pipe (323) is located at the lower part of the cooling chamber (31). The automatically adjustable low-temperature storage device according to feature 3.

5. The automatically adjustable low-temperature storage device according to claim 3, further comprising a control mechanism (4) above the sample storage chamber (1), wherein the control mechanism (4) can freeze the cooling chamber (31).

6. The automatic adjustable cryogenic storage device according to claim 3, further comprising a pressure release assembly (5) in the cooling chamber (31), wherein the pressure release assembly (5) is capable of releasing pressure and exhausting the inside of the cooling chamber (31).

7. The rotating storage mechanism (2) can rotate the cooling chamber (31), The extended end of the refrigerator (32) is installed inside the cooling chamber (31), A cooling conductive liquid is installed in the cooling chamber (31). The cooling chamber (31) has a central rotation axis and its upper end is in communication with the refrigeration cycle mechanism (3). The automatically adjustable low-temperature storage device according to feature 2.

8. The automatic adjustable low-temperature storage device according to claim 2, characterized in that the rotating storage mechanism (2) can rotate the cooling chamber (31), the cooling chamber (31) has a structure integrated with a central rotating shaft, and liquid nitrogen is contained in the cooling chamber (31).

9. The rotary storage mechanism (2) includes a drive member (21) and a rotary storage assembly (22), A drive member (21) is provided in the sample storage chamber (1). The rotating storage assembly (22) is provided inside the sample storage chamber (1), The drive member (21) can be driven to rotate the rotary storage assembly (22), The rotating storage assembly (22) can store baskets. An automatically adjustable low-temperature storage device according to any one of claims 1 to 7.

10. The rotating storage assembly (22) includes a vertical storage frame (221), Multiple sets of the aforementioned vertical storage frames (221) are arranged as storage disks (222) around the circumference. A gear disc (223) is installed at the upper end of the storage disc (222). The drive member (21) can be driven to rotate the gear disc (223). The automatically adjustable low-temperature storage device according to feature 9.

11. A drive member (21) is installed at the upper end of the sample storage chamber (1). A gear disc (223) is installed at the upper end of the cooling chamber (31), and the gear disc (223) is installed on one side of the drive member (21). The drive member (21) can be driven to rotate the gear disc (223) and the cooling chamber (31). A rotating storage assembly (22) is installed inside the sample storage chamber (1). The cooling chamber (31) can rotate the rotating storage assembly (22). The automatically adjustable low-temperature storage device according to feature 8.

12. The rotating storage assembly (22) includes a vertical storage frame (221), Multiple sets of the aforementioned vertical storage frames (221) are arranged around the circumference as storage disks (222), A rotating disk (225) is installed at the upper end of the storage disk (222). The rotating disk (225) is connected to the cooling chamber (31), The rotation of the cooling chamber (31) allows the rotating disk (225) and the storage disk (222) to rotate. The automatically adjustable low-temperature storage device according to feature 11.

13. The automatically adjustable cryogenic storage device according to any one of claims 1 to 8, characterized in that a vertical passage mechanism (6) is installed in the sample storage chamber (1), and the samples in the rotating storage mechanism (2) can be accessed via the vertical passage mechanism (6).

14. The vertical passage mechanism (6) includes a vertical passage, a passage door driving member (61), a transmission member (62), and a passage door (63), wherein a vertical passage is provided in the sample storage chamber (1), a passage door (63) is provided in the vertical passage, the passage door (63) is connected to the upper passage door driving member (61) via the transmission member (62), and the passage door driving member (61) drives the passage door (63) via the transmission member (62) to open and close the vertical passage, as described in 13.

15. The automatically adjustable low-temperature storage device according to any one of claims 1 to 8, further comprising a control box (7), wherein the control box (7) is installed on the side of the sample storage chamber (1), and the control box (7) can control the temperature inside the sample storage chamber (1).

16. The automatically adjustable low-temperature storage device according to claim 15, characterized in that a power distribution system (71), a condenser (72), and a control member (73) are installed in the control box (7), the power distribution system (71) distributes power to the device, and the condenser (72) and the control member (73) can perform temperature control for the sample storage chamber (1).

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