Pharmaceutical composition for preventing or treating nervous system diseases
Patent Information
- Application Number
- JP2021550238
- Authority / Receiving Office
- JP · JP
- Patent Type
- Patents
- Current Assignee / Owner
- Priority Date
- 2019-02-28
- Filing Date
- 2020-02-28
- Publication Date
- 2024-12-16
- Estimated Expiration
- 2040-02-28
AI Technical Summary
Current treatments for nervous system diseases are inadequate in effectively preventing or treating conditions such as Alzheimer's disease, vascular dementia, Parkinson's disease, and other neurological disorders due to the lack of pharmaceutical compositions that enhance the function of paraoxonase enzymes, which play a crucial role in mitigating oxidative stress and inflammation.
A pharmaceutical composition containing a pyrano[2,3-f]chromene derivative compound, its pharmaceutically acceptable salts, or solvates, which acts as a PONase activator, improving anti-inflammatory indicators and mitochondrial function, thereby addressing the underlying causes of these diseases.
The pyrano[2,3-f]chromene derivative compound demonstrates significant neuroprotective effects by enhancing paraoxonase enzyme activity, reducing oxidative stress, and alleviating inflammation, thus providing effective prevention and treatment for a range of neurological disorders.
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Abstract
Citation Information
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