Tick behavior inhibitor
Patent Information
- Application Number
- JP2020178325
- Authority / Receiving Office
- JP · JP
- Patent Type
- Patents
- Current Assignee / Owner
- Priority Date
- 2019-11-29
- Filing Date
- 2020-10-23
- Publication Date
- 2025-02-19
- Estimated Expiration
- 2040-10-23
AI Technical Summary
【0007】 本発明のダニ行動抑制剤は、(A)ダニ忌避成分による、ダニに対する忌避効果により処理区域外からのダニの侵入を防ぎ、処理区域にダニを寄せ付けないだけでなく、(A)成分と(B)成分との併用により、ダニの行動を抑制するため、処理区域内に生息していたダニの移動のみならず、摂食行動や生殖行動をも抑制して、ダニの増殖を著しく低減することができ、最終的にはダニの生息数を激減させて、ダニを防除することができ有用である。
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Abstract
Description
[Technical field]
[0001] The present invention relates to a mite behavior inhibitor and a method for inhibiting mite behavior using the same. [Background technology]
[0002] Conventionally, various mite control agents have been studied to reduce damage caused by indoor dust mites such as Dermatophagoides pteronyssinus. Among them, mite repellents are widely used, and mite repellents containing dibasic acid esters such as dibutyl sebacate as repellent components are known (for example, Patent Documents 1 and 2, etc.). Such mite repellents have the effect of repelling (keeping away) mites in an area treated with the repellent component. However, there has been a problem in that mites living in an area treated with the repellent component or mites that have repelled the area simply move outside the area, and after moving, they feed and reproduce, multiplying outside the treated area. [Prior art documents] [Patent documents]
[0003] [Patent Document 1] JP 2011-132196 A [Patent Document 2] JP 2007-230894 A Summary of the Invention [Problem to be solved by the invention]
[0004] The present invention aims to impart a mite behavior suppression function to a mite repellent component. [Means for solving the problem]
[0005] As a result of extensive research into solving the above problems, the present inventors discovered that mite behavior can be suppressed by combining a known mite repellent component with polyvinylpyrrolidone and / or polyvinyl alcohol, thereby solving the above problems.
[0006] Specifically, the present invention relates to the following items. 1. A mite behavior inhibitor comprising (A) a mite repellent component and (B) polyvinylpyrrolidone and / or polyvinyl alcohol as active ingredients. 2. The mite behavior inhibitor described in 1., characterized in that (A) the mite repellent component is a dibasic acid dialkyl ester. 3. A method for suppressing the behavior of mites present in an area in which mites may inhabit, by treating the area with the mite behavior inhibitor described in 1. Effect of the Invention
[0007] The mite behavior inhibitor of the present invention not only prevents the intrusion of mites from outside the treated area by the mite repellent effect of the (A) mite repellent component, keeping mites away from the treated area, but also suppresses mite behavior by combining the (A) component with the (B) component, thereby suppressing not only the movement but also the feeding and reproductive behavior of mites living within the treated area, significantly reducing mite proliferation, and ultimately drastically reducing the mite population and controlling mites, making it useful. [Brief description of the drawings]
[0008] [Figure 1] FIG. 1 is a schematic diagram showing an experimental apparatus for explaining the test method of the "mite migration distance confirmation test" in the examples. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS
[0009] The mite behavior inhibitor of the present invention and the method for inhibiting mite behavior using the same will be described in detail below. In addition, in the present invention, "behavioral inhibition" means inhibition not only of the migratory behavior of mites, but also of feeding behavior, reproductive behavior such as mating and egg-laying, and inhibition of escape behavior from cleaning tools intended to remove mites, such as vacuum cleaners and sticky sheets.
[0010] The mite behavior inhibitor of the present invention contains (A) a mite repellent component as an active ingredient. <Component (A)> The mite repellent component (A) of the present invention may be any known mite repellent component, and is not particularly limited.Specific examples include dibasic acid dialkyl esters represented by the following formulas (1) to (4), cinnamic acid derivatives such as cinnamyl acetate, benzyl cinnamate, and methyl cinnamate, benzoic acid esters such as amyl benzoate and isoamyl benzoate, salicylic acid esters such as amyl salicylate, isoamyl salicylate, and hexyl salicylate, terpenes such as α,β-pinene, α,β-terpineol, limonene, menthol, and p-menthane-3,8-diol, and essential oils containing them. [ka] (In formulas (1) to (4), R represents an alkyl group having 1 to 8 carbon atoms, and two R in a molecule may be the same or different. In addition, in formula (1), n represents an integer of 0 to 8.) Among these known mite repellent components, the dibasic acid dialkyl esters represented by the above formulas (1) to (4) are preferred as component (A) of the present invention. In the present invention, the term "dibasic acid dialkyl ester" refers to the group of compounds represented by the above formulas (1) to (4). Among them, the aliphatic dibasic acid dialkyl ester represented by the above formula (1) is preferred as component (A) of the present invention. Further, as the component (A) of the present invention, specific examples of the aliphatic dibasic acid dialkyl ester represented by formula (1), such as diethyl oxalate, dimethyl malonate, diethyl malonate, dimethyl succinate, diethyl succinate, dipropyl succinate, dibutyl succinate, dimethyl glutarate, diethyl adipate, dipropyl adipate, dibutyl adipate, dioctyl adipate, diethyl sebacate, dipropyl sebacate, dibutyl sebacate, dioctyl sebacate, dimethyl phthalate, dibutyl phthalate, diamyl phthalate, dibutyl maleate and dibutyl fumarate are more preferred, and dipropyl adipate, dibutyl adipate, dioctyl adipate, dibutyl sebacate and dioctyl sebacate are particularly preferred.
[0011] The content of the mite repellent component (A) in the mite behavior inhibitor of the present invention is not particularly limited and may be appropriately set, but is preferably 0.01 to 5 w / v%, more preferably 0.1 to 2 w / v%, based on the entire mite behavior inhibitor. By making it 0.01 w / v% or more, excellent mite repellent effect can be obtained, and in addition, by using it in combination with polyvinylpyrrolidone and / or polyvinyl alcohol, which are the component (B) of the present invention, excellent mite behavior inhibitory effect can be obtained. In addition, by making it 5 w / v% or less, the influence on various members on the treatment surface of the mite behavior inhibitor can be reduced, which may be preferable.
[0012] <(B) component> The mite behavior inhibitor of the present invention contains (B) polyvinylpyrrolidone and / or polyvinyl alcohol as an active ingredient. The polyvinylpyrrolidone in the present invention is a water-soluble polymeric compound obtained by polymerization of N-vinyl-2-pyrrolidone. The weight-average molecular weight of the polyvinylpyrrolidone used is not particularly limited, but may be, for example, about 5,000 to 3,000,000, more preferably about 30,000 to 400,000. Here, the weight-average molecular weight of the polyvinylpyrrolidone refers to a value measured by gel filtration chromatography / multi-angle light scattering photometer (GPC / MALLS). The K value (viscosity characteristic value) of the polyvinylpyrrolidone is not particularly limited, but preferably about 10 to 100 can be used. In addition, in the present invention, commercially available polyvinylpyrrolidone can be used. Specific examples of commercially available polyvinylpyrrolidone include "Eiftact K-30PH" manufactured by Daiichi Kogyo Seiyaku Co., Ltd., "Polyvinylpyrrolidone K-30", "Polyvinylpyrrolidone K-85", and "Polyvinylpyrrolidone K-90" manufactured by Nippon Shokubai Co., Ltd., and "PVP K-90" manufactured by ISP Japan. The polyvinyl alcohol in the present invention is a water-soluble polymer having a hydroxyl group, which is obtained by hydrolyzing polyvinyl acetate with an acid or an alkali. The weight-average molecular weight of the polyvinyl alcohol used is not particularly limited, but may be, for example, about 10,000 to 300,000, more preferably about 30,000 to 200,000. Here, the weight-average molecular weight of the polyvinyl alcohol refers to a value measured by gel filtration chromatography / multi-angle light scattering photometer (GPC / MALLS). In addition, in the present invention, a commercially available polyvinyl alcohol may be used. Specific examples of commercially available polyvinyl alcohol include "GOHSENOL EG-05C" and "GOHSENOL EG-40C" manufactured by Nippon Synthetic Chemical Industry Co., Ltd. The component (B) in the present invention may be polyvinylpyrrolidone alone, polyvinyl alcohol alone, or a combination of polyvinylpyrrolidone and polyvinyl alcohol.
[0013] The content of polyvinylpyrrolidone and / or polyvinyl alcohol (B) in the mite behavior inhibitor of the present invention is not particularly limited and may be appropriately determined, but is preferably 0.01 to 10 w / v%, more preferably 0.05 to 5 w / v%, based on the total amount of the mite behavior inhibitor. By making it 0.01 w / v% or more, an excellent mite behavior inhibitory effect can be obtained due to the synergistic effect with the mite repellent component (A). In addition, by making it 10 w / v% or less, the influence of the mite behavior inhibitor on various components on the treatment surface can be reduced, which may be preferable.
[0014] <Tick> Examples of mites whose behavior can be inhibited by the mite behavior inhibitor of the present invention include house dust mites living indoors, such as Dermatophagoides farinae and Dermatophagoides pteronyssinus, grain mites such as Dermatophagoides contortrix, Tyrophagus putrescentiae, and Acarid mites, such as Dermatophagoides persulcatus, Dermatophagoides japonica, and Dermatophagoides scaly, cheyletid mites such as Dermatophagoides stag beetle, Dermatophagoides pallidus, Dermatophagoides nervosa, and Dermatophagoides scaly, house mites such as Dermatophagoides edulis, Dermatophagoides stag beetle, Dermatophagoides scaly, Dermatophagoides scaly, and Dermatophagoides scaly, house mites such as Dermatophagoides edulis, Dermatophagoides pedunculata, Dermatophagoides mites, Dermatophagoides pedunculata ...
[0015] <Preparation> The mite behavior inhibitor of the present invention contains the above (A) mite repellent component and (B) polyvinylpyrrolidone and / or polyvinyl alcohol, and although the mixture may be used as is, it is usually used as a formulation. The formulation form may be appropriately set according to the mode of use. For example, it can be in the form of an oil solution, an emulsion, a wettable powder, a granule, a spray, an aerosol, a spray, a coating agent, a cleaning agent, a sheet agent, an injection agent, etc. Preferred formulation forms are a spray, an aerosol, a spray, and a sheet agent, which are easy to use and can be used repeatedly, making them easy to use. Among them, by preparing it as a liquid agent and using it as a spray formulation such as a spray agent or an aerosol agent, the mite behavior inhibitor of the present invention can be directly attached to the mite in a liquid state, and therefore the performance of the mite behavior inhibitor can be maximized, which is preferable. The mite behavior inhibitor of the present invention exerts its maximum behavior-inhibiting effect by directly adhering to the body surface of the mite, and therefore the formulation form is preferably a liquid formulation.
[0016] When preparing the liquid preparation of the mite behavior inhibitor of the present invention, it is possible to mix nonionic, anionic, cationic surfactants, etc., as necessary.Specifically, for example, nonionic surfactants such as alkylaryl ethers, polyoxyethylene derivatives of alkylaryl ethers, polyethylene glycol ethers, polyethylene glycol fatty acid esters, polyoxyethylene fatty acid esters, polyoxyethylene polyoxypropylene copolymers, polyoxyethylene hydrogenated castor oils, polyhydric alcohol esters and sugar alcohol derivatives, anionic surfactants such as alkyl sulfate ester salts, alkyl sulfonates, alkylaryl sulfonates, and cationic surfactants such as alkyl ammonium halides.Among them, when the stock solution of the mite behavior inhibitor of the present invention is made into an aqueous solution, it is preferable to mix nonionic surfactants such as polyoxyethylene alkyl ethers, polyoxyethylene alkylphenyl ethers, polyoxyethylene hydrogenated castor oils, glycerin fatty acid esters, alkyl glyceryl ethers, polyoxyethylene glyceryl ethers, and sorbitan fatty acid esters.
[0017] The mite behavior inhibitor of the present invention may be blended with other known liquid carriers, gaseous carriers, solid carriers, and other formulation auxiliary agents. Examples of liquid carriers include aromatic or aliphatic hydrocarbons (xylene, toluene, alkylnaphthalene, phenylxylylethane, kerosene, diesel, hexane, cyclohexane, liquid paraffin, etc.), halogenated hydrocarbons (chlorobenzene, dichloromethane, dichloroethane, trichloroethane, etc.), alcohols (methanol, ethanol, isopropyl alcohol, butanol, hexanol, benzyl alcohol, ethylene glycol, etc.), ethers (diethyl ether, ethylene glycol dimethyl ether, diethylene glycol monomethyl ether, diethylene glycol monoethyl ether, propylene glycol monomethyl ether, tetrahydrofuran, dioxane, etc.), and esters. (ethyl acetate, butyl acetate, isopropyl myristate, ethyl lactate, ethyl benzoate, etc.), ketones (acetone, methyl ethyl ketone, methyl isobutyl ketone, cyclohexanone, etc.), nitriles (acetonitrile, isobutyronitrile, etc.), sulfoxides (dimethyl sulfoxide, etc.), heterocyclic solvents (sulfolane, γ-butyrolactone, 1,3-dimethyl-2-imidazolidinone), acid amides (N,N-dimethylformamide, N,N-dimethylacetamide, N-methyl-pyrrolidone, 3-methoxy-N,N-dimethylpropionamide, etc.), alkylidene carbonates (propylene carbonate, etc.), vegetable oils (soybean oil, cottonseed oil, etc.), vegetable essential oils (orange oil, hyssop oil, lemon oil, etc.), and water. Examples of gaseous carriers include butane gas, fluorocarbon gas, alternative fluorocarbons (such as HFO and HFC), liquefied petroleum gas (LPG), dimethyl ether, nitrogen gas, and carbon dioxide gas. Examples of solid carriers include clays (kaolin, diatomaceous earth, bentonite, clay, acid clay, etc.), synthetic hydrous silicon oxide, talc, ceramics, other inorganic minerals (sericite, quartz, sulfur, activated carbon, calcium carbonate, hydrated silica, etc.), porous bodies, and the like.
[0018] The mite behavior inhibitor of the present invention can be used in combination with a known insecticide to prevent the intrusion of mites from outside the treatment area, inhibit the behavior of mites that exist in the treatment area, and then become a control drug that can reliably control mites. Examples of known insecticides that can be used in combination include pyrethroid compounds such as natural pyrethrins, allethrin, resmethrin, furamethrin, prallethrin, telallethrin, phthalthrin, fenothrin, permethrin, cyphenothrin, cypermethrin, transfluthrin, metofluthrin, profluthrin, imiprothrin, empenthrin, etofenprox, silafluofen, meperfluthrin, and dimefluthrin; carbamate compounds such as propoxur and carbaryl; organophosphorus compounds such as fenitrothion and DDVP; and oxadiazone. Examples of the insecticides include diazole compounds, phenylpyrazole compounds such as fipronil, sulfonamide compounds such as amidoflumet, neonicotinoid compounds such as imidacloprid and dinotefuran, insect juvenile hormone-like compounds such as pyriproxyfen, methoprene, and hydroprene, anti-juvenile hormone-like compounds such as precocene, chitin synthesis inhibitors such as novaluron and diflubenzuron, and insecticidal essential oils such as phytoncides, peppermint oil, orange oil, cinnamon oil, and clove oil, and further, synergists such as sinepirin and piperonyl butoxide can also be used in combination. On the other hand, since the mite behavior inhibitor of the present invention is mainly intended to be used indoors, it is preferable not to use these insecticides in combination, considering the safety of humans such as infants and young children living indoors and animals such as pets.
[0019] Other formulation adjuvants include adhesives, dispersants, solubilizing agents, and stabilizers, such as casein, gelatin, polysaccharides (starch, gum arabic, cellulose derivatives, alginic acid, etc.), lignin derivatives, sugars, synthetic water-soluble polymers (polyvinyl alcohol, polyacrylic acid, etc.), benzoic acid esters and salts, BHT (2,6-di-tert-butyl-4-methylphenol), and BHA (a mixture of 2-tert-butyl-4-methoxyphenol and 3-tert-butyl-4-methoxyphenol). In the present invention, further, if necessary, components such as rust inhibitors, preservatives, pH adjusters, and fragrances can be appropriately added. As these components, those commonly used in this field can be used, and specifically, examples of rust inhibitors include Carlen No. 955, No. 906, No. 954, No. 958, and No. 970 (all trademarks of Sanyo Chemical Industries, Ltd.), etc., preservatives include methyl paraoxybenzoate, ethyl paraoxybenzoate, propyl paraoxybenzoate, butyl paraoxybenzoate, isothiazolinone, sodium salicylate, sodium benzoate, phenoxyethanol, potassium sorbate, and sodium dehydroacetate, and pH adjusters include organic acids such as acetic acid, lactic acid, succinic acid, maleic acid, tartaric acid, citric acid, ascorbic acid, salicylic acid, and benzoic acid, inorganic acids such as phosphoric acid, and their salts.
[0020] When the mite behavior inhibitor of the present invention is filled into an aerosol spray container, a wide variety of known propellants can be used, including, for example, butane gas, chlorofluorocarbon gas, alternative chlorofluorocarbons (HFO, HFC, etc.), liquefied petroleum gas (LPG), dimethyl ether, nitrogen gas, and carbon dioxide gas. In this mite behavior inhibitor, the amount of propellant can be 10 to 95% by volume, particularly 30 to 90% by volume, of the entire mite behavior inhibitor. When producing the mite behavior inhibitor of the present invention, methods commonly used in this field can be widely used. Among them, a representative method is a method in which the blending components are heated (30 to 50°C) and mixed as necessary to prepare a uniform solution, and then a rust inhibitor, a preservative, etc. are added, and the resulting stock solution is placed in an aerosol spray container, and the propellant is filled to produce a product. The mite behavior inhibitor of the present invention obtained in this way can be stable even under harsh conditions for a long period of time, and can maintain a uniform state, and can be sprayed into the air as fine particles with one touch when desired.
[0021] The mite behavior inhibitor of the present invention is not particularly limited in terms of the place or object of application as long as it is an indoor environment where the above-mentioned indoor dust mites live or occur. For example, the main objects of application are bedding such as beds, futons, pillows, mattresses, blankets, etc., fabric products such as curtains, sofas, carpets, stuffed toys, tatami mats, carpets, chairs, chests, closets, wallpaper, etc., where mites should not be attracted or may be present, and it can also be sprayed on seats in cars, strollers, etc. The mite behavior inhibitor of the present invention can suppress mite behavior by applying to the target an amount of 0.8 mg or more of the total amount of the mite repellent component (A) and polyvinylpyrrolidone and / or polyvinyl alcohol (B) per square meter of the treatment surface. In order to obtain a more sufficient effect, the amount of 1.2 to 1200 mg / m 2 , more preferably 6 to 560 mg / m 2 can be applied. EXAMPLES
[0022] The present invention will be described in more detail below with reference to formulation examples and test examples, but the present invention is not limited to these examples. In the examples, unless otherwise specified, all parts are by weight.
[0023] <Mite movement distance confirmation test> (1) Preparation of test samples A test specimen of Example 1 was obtained using 1 part by weight of dibutyl adipate as component (A), 0.01 part by weight of polyvinylpyrrolidone ("Polyvinylpyrrolidone K-90" manufactured by Nippon Shokubai Co., Ltd., weight average molecular weight: approximately 360,000) as component (B), 50 parts by weight of ethanol, and purified water, with the total amount being 100 parts by weight. A test specimen for Example 2 was obtained using 1 part by weight of dibutyl adipate as component (A), 0.01 part by weight of polyvinyl alcohol (Gohsenol EG-40C, manufactured by Nippon Synthetic Chemical Industry Co., Ltd.) as component (B), 50 parts by weight of ethanol, and purified water, with the total amount being 100 parts by weight. In Comparative Examples 1 to 4, test specimens were obtained in the same manner as in Example 1 using the compositions shown in Table 1 below. In Table 1, "DBA" means dibutyl adipate, "PVP" means polyvinylpyrrolidone, and "PVA" means polyvinyl alcohol.
[0024] [Table 1]
[0025] (2) Test method for confirming mite movement distance FIG. 1 is a schematic diagram showing an experimental apparatus for explaining a mite migration distance confirmation test method. A petri dish 1 with a diameter of 15 cm was placed on a paper with concentric circles drawn with a radius of 0.5 cm increasing, so that the centers overlapped, and about 0.05 g (about 3000 mites) of test insects dyed blue (Dermatophagoides pteronyssinus) were placed in the center of the petri dish 1. After leaving it for about 20 seconds until the clumped mites were dispersed, about 1 mL of each test specimen of Examples 1 and 2 and Comparative Examples 1 to 4 was sprayed from a distance of 20 cm directly above the petri dish 1 using a spray container with a trigger. Next, as shown in FIG. 1, black paper 2 with 3 cm squares on which mite food (fresh medium) was placed was placed in four places on the petri dish 1, and the mites were visually observed after 20 minutes. The position furthest from the center where three or more mites were confirmed was determined as the mite mobility of the test specimen. The test was carried out twice, and the average value of this mobility (20 minutes) was converted into the migration distance per 24 hours. The numerical value ("migration distance (cm / 24 hours)") is summarized in Table 2 below.
[0026] [Table 2]
[0027] As shown in Table 2, it was confirmed that the mites sprayed with the test specimens of Examples 1 and 2, which are specific examples of the present invention, were inhibited in their behavior and did not move at all. On the other hand, it was also revealed that the mites sprayed with the test specimens of Comparative Examples 1 to 4 moved more actively and significantly than the mites sprayed with the test specimens of Examples 1 and 2. In particular, Comparative Example 1 is a test specimen containing dibutyl adipate, which is a known component as a mite repellent, but it was revealed that the mites sprayed with the mite repellent only moved significantly outside the treated area, and no mite behavior inhibition effect was obtained. In addition, it was confirmed that Comparative Example 2, which is a test specimen containing only polyvinylpyrrolidone, and Comparative Example 3, which is a test specimen containing only polyvinyl alcohol, also did not obtain any mite behavior inhibition effect. These results demonstrate that the mite behavior inhibitor of the present invention exerts a "synergistic" mite behavior inhibitory effect when used in combination with component (A) and component (B).
[0028] <Mite activity evaluation test> (1) Preparation of test samples The test samples used were those from Examples 1 and 2 and Comparative Examples 1 to 4 in the above-mentioned "mite migration distance confirmation test." (2) Test method for evaluating mite activity Approximately 100 test insects (Dermatophagoides pteronyssinus) were placed in the center of a petri dish with a diameter of 9 cm. Approximately 1 mL of each test specimen from Examples 1 and 2 and Comparative Examples 1 to 4 was sprayed from a trigger-equipped spray container from a distance of 20 cm directly above the petri dish 1. The test insects were observed under a stereomicroscope immediately after spraying and 24 hours later for activity. The test was performed twice, and the ratio of active test insects to the total number of test insects, "the ratio of active mites immediately after spraying (%)" and "the ratio of active mites 24 hours later (%)", was calculated, and the average values are summarized in Table 3 below. In addition, active test insects refer to individuals that can walk freely or individuals that are not walking but are moving their legs. Individuals that are moving their legs were judged to be capable of reproduction through mating. Inactive test insects refer to either dead individuals, individuals that are unable to walk and only move their legs slightly, or individuals that are stuck together and cannot move.
[0029] [Table 3]
[0030] As shown in Table 3, it was confirmed that the mites sprayed with the test specimens of Examples 1 and 2, which are specific examples of the present invention, were inhibited in their behavior immediately after spraying and 24 hours later, and were almost inactive. On the other hand, it was revealed that the mites sprayed with the test specimens of Comparative Examples 1 to 4 were active not only immediately after spraying but also 24 hours later, compared to the mites sprayed with the test specimens of Examples 1 and 2. In particular, Comparative Example 1 is a test specimen containing dibutyl adipate, which is a known component as a mite repellent, but it was confirmed that the activity of the mites sprayed with the mite repellent was not sufficiently inhibited, and 24 hours later, 8 times as many mites were active compared to Example 1. In other words, it was revealed that the treatment agent containing only the mite repellent, which is the component (A) of the present invention, does not have a mite behavior inhibition effect, and the mites move outside the treated area to feed and reproduce, and may multiply outside the treated area. It was also confirmed that the mites were active in Comparative Example 2, which is a test specimen containing only polyvinylpyrrolidone, and Comparative Example 3, which is a test specimen containing only polyvinyl alcohol. These results demonstrate that the mite behavior inhibitor of the present invention exerts a "synergistic" mite behavior inhibitory effect when used in combination with component (A) and component (B). [Industrial Applicability]
[0031] The mite behavior inhibitor of the present invention not only prevents the intrusion of mites from outside the treated area by the mite repellent effect of the (A) mite repellent component, keeping mites away from the treated area, but also inhibits mite behavior by using the (A) component in combination with the (B) component, thereby suppressing not only the movement of mites living in the treated area, but also their feeding behavior and reproductive behavior, thereby significantly reducing mite proliferation and ultimately drastically reducing the mite population, making it useful for controlling mites.
Claims
1. A mite behavior inhibitor characterized in that it is a liquid formulation, and contains (A) an aliphatic dibasic acid dialkyl ester represented by the following formula (1) as a mite repellent component, and (B) polyvinylpyrrolidone and / or polyvinyl alcohol as active ingredients. (Chem.1) R-OOC(CH 2 ) n COO-R (1) (In formula (1), R represents an alkyl group having 1 to 8 carbon atoms, two R's in a molecule may be the same or different, and n represents an integer of 0 to 8.)
2. A mite behavior inhibitor as described in claim 1, characterized in that the (A) mite repellent component is dibutyl adipate.
3. A method for suppressing the behavior of mites in an area in which mites may inhabit, comprising treating the area with the mite behavior inhibitor according to claim 1.
Citation Information
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