Capsules for gastrointestinal sampling

JP7733787B2Active Publication Date: 2025-09-03ELI LILLY & CO
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Patent Information

Application Number
JP2024177082
Authority / Receiving Office
JP · JP
Patent Type
Patents
Current Assignee / Owner
Priority Date
2019-12-16
Filing Date
2024-10-09
Publication Date
2025-09-03
Estimated Expiration
2040-12-16

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Abstract

To provide a passive sampling digestive device capable of sealing a capsule when collected from a desired part of a digestive tract.SOLUTION: A device includes a capsule housing 202 containing an absorbent sampling hydrogel 214. The capsule may be ingested by a patient and subsequently travel through the gastrointestinal tract. Once the capsule reaches a desired location in the gastrointestinal tract, gastrointestinal fluid may flow into the capsule through a sampling aperture 208 of the capsule. The fluid may be absorbed by and stored within the sampling hydrogel for subsequent analysis, and the absorption of the fluid may cause the sampling hydrogel to expand within the capsule. The capsule may further include a sealing member 216 positioned between the sampling hydrogel and the sampling aperture, and the expansion of the sampling hydrogel may press the sealing member against the sampling aperture to seal the capsule.SELECTED DRAWING: Figure 2A
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Citation Information

Patent Citations

  • Sampling device

    JP2019150587A

  • Sampling Systems and Related Materials and Methods

    JP2019528117A

  • Device for collecting intestinal fluid

    WO2019081539A1