5-HT2A receptor inhibitors or inverse agonists, their preparation method, and their uses

JP7797473B2Active Publication Date: 2026-01-13GENEORA PHARMA (SHIJIAZHUANG) CO LTD
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Patent Information

Application Number
JP2023504487
Authority / Receiving Office
JP · JP
Patent Type
Patents
Current Assignee / Owner
Priority Date
2021-04-03
Filing Date
2021-07-22
Publication Date
2026-01-13
Estimated Expiration
2041-07-22

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Abstract

The present invention is directed to the use of 5-HT 2A The present invention also relates to novel compounds as 5-HT receptor inhibitors or inverse agonists, methods for their preparation, and pharmaceutical compositions thereof. 2A The present invention relates to the use of a compound or pharmaceutical composition in the preparation of a medicament for treating a receptor-related disease, including non-motor symptoms caused by Parkinson's disease: delusions, hallucinations, depression, anxiety, cognitive impairment, and sleep disorders; dementia-related psychosis; major depressive disorder; or negative symptoms of schizophrenia.
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Citation Information

Patent Citations

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    JP2003516965A

  • Selective serotonin 2a / 2c receptor inverse agonists as therapeutic agents for neurodegenerative diseases

    JP2006516284A

  • Aromatic heterocyclic derivative having serotonin receptor binding activity

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