visceral fat accumulation reduction agent
A dietary model with 13% casein and low potassium in rats, combined with alkalizing agents like citrates, addresses visceral fat accumulation and metabolic disorders from high-protein diets, improving insulin resistance and adrenal function, and reducing visceral fat and acidification.
Patent Information
- Authority / Receiving Office
- JP · JP
- Patent Type
- Patents
- Current Assignee / Owner
- UNIVERSITY OF THE RYUKYUS
- Filing Date
- 2024-01-16
- Publication Date
- 2026-05-22
AI Technical Summary
Existing models fail to reproduce visceral fat accumulation caused by high-protein diets, and there is a lack of research on the mechanisms and pharmaceuticals to address metabolic disorders associated with excessive protein intake, particularly affecting insulin resistance, pituitary and adrenal functions, and visceral fat accumulation.
A dietary model using 13% casein and low potassium (0.3%) in rats is developed to replicate visceral fat accumulation, and alkalizing agents like citrates are used to improve metabolic abnormalities, including insulin resistance and adrenal function, by reducing visceral fat, acidification, and normalizing the hypothalamic-pituitary-adrenal axis.
The model effectively reproduces visceral fat accumulation and metabolic disorders from high-protein diets, and alkalizing agents like citrates improve insulin resistance, adrenal function, and reduce visceral fat, acidification, and normalize the HPA axis, providing a metabolic improving agent for metabolic syndrome.
Smart Images

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