Adhesive patch

A support layer with high moisture permeability in transdermal patches addresses the adhesion issue of DMSO-containing patches, ensuring prolonged adhesion and effective drug delivery.

JP7864169B2Active Publication Date: 2026-05-22HISAMITSU PHARM CO INC
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Patent Information

Authority / Receiving Office
JP · JP
Patent Type
Patents
Current Assignee / Owner
HISAMITSU PHARM CO INC
Filing Date
2024-11-01
Publication Date
2026-05-22

AI Technical Summary

Technical Problem

The adhesion of transdermal patches containing DMSO in the adhesive layer decreases over time, leading to potential peeling before the treatment is completed, especially when applied for extended periods.

Method used

Incorporating a support layer with high moisture permeability into the adhesive patch, which allows DMSO to volatilize gradually, maintaining adhesion and preventing peeling.

Benefits of technology

Ensures sustained adhesion of the patch for extended periods, enhancing drug permeability and achieving consistent plasma concentration of drugs like ketoprofen, diclofenac sodium, or indomethacin.

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Patent Text Reader

Abstract

To provide a patch that does not fall off easily even when applied to the skin for a long time.SOLUTION: A patch of the present invention comprises a supporting layer and an adhesive layer laminated on the supporting layer, where a water vapor transmission rate of the supporting layer is 400 g / m2 24 hours or more, and the adhesive layer comprises a drug, dimethylsulfoxide and an adhesive.SELECTED DRAWING: None
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