Ozone bubbling device

The ozone bubbling device addresses side effects of dermatitis treatments by using ozone-enriched water immersion to safely improve dermatitis symptoms and skin conditions, including allergic and seborrheic dermatitis, with minimal adverse effects.

JP7883243B2Active Publication Date: 2026-07-01RENERO PHARMA CO LTD +1

Patent Information

Authority / Receiving Office
JP · JP
Patent Type
Patents
Current Assignee / Owner
RENERO PHARMA CO LTD
Filing Date
2025-02-04
Publication Date
2026-07-01

AI Technical Summary

Technical Problem

Existing dermatitis treatments using anti-inflammatory drugs pose concerns about side effects, necessitating a safer alternative for improving inflammation and skin conditions.

Method used

An ozone bubbling device that generates and supplies ozone-containing gas to water in a bathtub, allowing the affected area to be immersed, thereby enriching the water with ozone for treating dermatitis.

Benefits of technology

The ozone bubbling device effectively alleviates dermatitis symptoms with low side effects, improving conditions such as allergic and seborrheic dermatitis, and enhances skin health by reducing symptoms like coat shine, hair loss, desquamation, body odor, and oiliness-dryness balance.

✦ Generated by Eureka AI based on patent content.

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Abstract

To provide an ozone bubbling device for improving dermatitis or skin conditions.SOLUTION: An ozone bubbling device includes: an ozone generation part for generating gas containing ozone; a bathtub part formed so that water can be stored therein; and an ozone supply part for supplying gas containing ozone generated by the ozone generation part, in water stored in the bathtub part. The ozone supply part is provided on the bottom surface of the bathtub part, and is configured to be able to supply gas containing the ozone to the water stored in the bathtub part by bubbling from a plurality of supply parts of a discharge part formed by connecting the plurality of supply parts to each other via piping.SELECTED DRAWING: Figure 1
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Description

Technical Field

[0001] The present invention relates to an ozone bubbling device for improving dermatitis and skin conditions, which is effective for improving the inflammation and skin conditions of dermatitis such as allergic dermatitis, and a method for improving dermatitis and skin conditions. [[ID=VI]] [[ID=VII]]

Background Art

[0002] [[ID=XI]] [[ID=XII]]Conventionally, in the treatment of dermatitis, treatment has been carried out using external preparations containing anti-allergic agents and the like. For example, in Patent Document 1, there is disclosed a skin external composition for suppressing itching of inflammatory diseases, which contains dihomo-γ-linolenic acid (DGLA) as an active ingredient, and is characterized in that a preparation containing 0.01 to 50% by weight of dihomo-γ-linolenic acid (DGLA) at the onset site of the inflammatory disease is continuously applied for at least 14 days or more. [[ID=XIII]] [[ID=XIV]]

Prior Art Documents

Patent Documents

[0003] [[ID=XXI]] [[ID=XXII]] [[ID=XXIII]]

Patent Document 1

Summary of the Invention

Problems to be Solved by the Invention

[0004] [[ID=XXXIV]] [[ID=XXXV]]However, although drugs exhibit a strong anti-inflammatory effect, there are concerns about side effects. Therefore, in terms of the side effects of drugs, the emergence of safer means for improving inflammation and skin conditions is expected. [[ID=XXXVI]] [[ID=XXXVII]]

[0005] [[ID=XXXVIII]] [[ID=XXXIX]]Therefore, the present invention has been made in view of the above problems, and an object thereof is to provide an ozone bubbling device for improving dermatitis and skin conditions, and a method for improving dermatitis and skin conditions, which have a low risk of side effect expression and can relieve the inflammation of dermatitis. [[ID=XL]] [[ID=XLI]]

Means for Solving the Problems

[0006] The present invention provides an ozone bubbling device for improving dermatitis and skin conditions, comprising: an ozone generating unit that generates a gas containing ozone; a bathtub unit formed to store water; and an ozone supply unit that supplies the gas containing ozone generated by the ozone generating unit to the water stored in the bathtub unit, wherein the bathtub unit is structured to allow the affected area, where improvement of dermatitis or skin condition is desired, to be immersed in the water stored in the bathtub unit.

[0007] The present invention provides an ozone bubbling device for improving dermatitis and skin conditions, which allows for the supply of ozone-containing gas to water stored in a bathtub while bubbling. As a result, the water stored in the bathtub can be enriched with ozone. The user can then improve their dermatitis by immersing the affected area in the water stored in the bathtub.

[0008] In the ozone bubbling device for improving dermatitis and skin conditions of the present invention, it is preferable to use it for improving allergic dermatitis.

[0009] In the ozone bubbling device for improving dermatitis and skin conditions of the present invention, it is preferable to use it for improving chronic seborrheic dermatitis.

[0010] In the ozone bubbling device for improving dermatitis and skin conditions of the present invention, it is preferable to use it to improve at least one symptom selected from coat shine, hair loss, desquamation, body odor, and the balance of oiliness and dryness.

[0011] The present invention provides a method for treating dermatitis and improving skin conditions, comprising: a water storage step of storing water in a bathtub; an ozone supply step of supplying a gas containing ozone to the stored water; and an immersion step of immersing the affected area of ​​an animal (excluding humans) whose dermatitis or skin condition is to be improved in the water in the bathtub.

[0012] According to the present invention's method for improving dermatitis and skin conditions, it is possible to supply an ozone-containing gas to the water stored in the bathtub while bubbling. As a result, the water stored in the bathtub can be made to contain ozone. The user can then improve their dermatitis by immersing the affected area in the water stored in the bathtub.

[0013] In the present invention's method for treating dermatitis and improving skin condition, the dermatitis is preferably allergic dermatitis.

[0014] In the present invention's method for treating dermatitis and improving skin conditions, the dermatitis is preferably chronic seborrheic dermatitis.

[0015] In the present invention's method for improving dermatitis and skin conditions, it is preferable to apply it to the improvement of at least one symptom selected from coat shine, hair loss, desquamation, body odor, and the balance of oiliness and dryness. [Brief explanation of the drawing]

[0016] [Figure 1] This is a conceptual diagram of an ozone bubbling device for improving dermatitis. [Figure 2] Figure 1 is a block diagram of the ozone generation unit. [Figure 3] Figure 1 is a plan view of the ozone supply unit. [Figure 4] Figure 3 is an enlarged plan view of the ozone supply unit. [Figure 5] This is a flowchart of methods for improving dermatitis. [Figure 6] This diagram shows the condition of the anterior neck before treatment with an ozone bubbling device for improving dermatitis. [Figure 7] This diagram shows the condition of the anterior neck after the first treatment using an ozone bubbling device for improving dermatitis. [Figure 8] This diagram shows the condition of the anterior neck after the second treatment using an ozone bubbling device for improving dermatitis. [Figure 9]The figure shows the state of the front neck after the third treatment with the ozone bubbling device for improving dermatitis. [Figure 10] The figure shows the state of the caudal abdomen before the treatment with the ozone bubbling device for improving dermatitis. [Figure 11] The figure shows the state of the caudal abdomen after the first treatment with the ozone bubbling device for improving dermatitis. [Figure 12] The figure shows the state of the caudal abdomen after the second treatment with the ozone bubbling device for improving dermatitis. [Figure 13] The figure shows the state of the caudal abdomen after the third treatment with the ozone bubbling device for improving dermatitis. [Figure 14] The figure shows the state of the front neck after the first treatment with the ozone bubbling device for improving dermatitis. [Figure 15] The figure shows the state of the front neck after the 21st treatment with the ozone bubbling device for improving dermatitis. [Figure 16] The figure shows the state of the front neck after the 56th treatment with the ozone bubbling device for improving dermatitis.

Embodiments for Carrying Out the Invention

[0017] FIG. 1 is a perspective view of an ozone bubbling device 100 for improving dermatitis (hereinafter also referred to as an ozone bubbling device). As shown in FIG. 1, it has an ozone generation unit 10 that generates a gas containing ozone, a bathtub unit 20 formed to be able to store water, and an ozone supply unit 30 that supplies the gas containing ozone generated by the ozone generation unit 10 to the water stored in the bathtub unit 20.

[0018] The ozone generation unit 10 is a device that generates a gas containing ozone and sends out the gas to the ozone supply unit 30.

[0019] The bathtub section 20 is structured to allow the affected area with dermatitis to be immersed in the water stored in the bathtub section 20. In this embodiment, the bathtub section 20 is formed in the shape of a box. The bathtub section 20 only needs to be able to allow the affected area to be immersed in the stored water and to accommodate the ozone supply section 30, and may be, for example, a water tank, a bathtub, etc. Furthermore, the bathtub section 20 is not limited to a box shape and may be bag-shaped.

[0020] The ozone supply unit 30 is connected to the ozone generation unit 10 by a connecting member 40. The ozone supply unit 30 supplies air containing ozone, which is sent out from the ozone generation unit 10, into the bathtub section 20.

[0021] The connecting member 40 is a piping member that connects the ozone generating unit 10 and the ozone supply unit 30. The connecting member 40 can be any member that serves as a gas passage and is not particularly limited, but for example, an annular rubber hose can be used.

[0022] Figure 2 shows the configuration of the ozone generating unit 10. As shown in Figure 2, the ozone generating unit 10 has a housing 11. The housing 11 is formed, for example, in the shape of a box.

[0023] The enclosure 11 houses a pump 12 that takes in air from outside the enclosure 11 and discharges pressurized air. The pump 12 receives power from an external source and discharges a fixed amount of air.

[0024] Furthermore, the housing 11 houses an ozone generator 13 that generates ozone from oxygen-containing air. The ozone generator 13 is a silent discharge type device that generates ozone gas by applying a high voltage to oxygen-containing air and causing a discharge.

[0025] Furthermore, the ozone generator 13 is not limited to a silent discharge type device; for example, it may be an electrolytic type device or an ultraviolet lamp type device.

[0026] The ozone generator 13 is connected to the pump 12 by a connecting member 50. The connecting member 50 is a piping member that connects the ozone generator 13 and the pump 12. The connecting member 50 can be any member that serves as a gas passage and is not particularly limited, but for example, an annular rubber hose can be used.

[0027] Therefore, the ozone generation unit 10 can generate an ozone-containing gas by mixing the ozone generated by the ozone generator 13 with the air sent from the pump 12.

[0028] Furthermore, the ozone generator 13 is connected to the connecting member 40. Therefore, the ozone generation unit 10 can send ozone-containing gas to the ozone supply unit 30 via the connecting member 40.

[0029] The ozone generator 13 has a timer (not shown). The ozone generator 13 may generate ozone according to the time counted by the timer. For example, when operating the ozone bubbling device 100 for a predetermined time, the operating time of the ozone generator 13 may be controlled by the timer.

[0030] Furthermore, the control of the operation of the ozone generator 13 is not limited to this timer method. For example, a detector for detecting ozone concentration may be provided in the bathtub section 20, and the operation may be controlled according to the ozone concentration in the bathtub section 20. In other words, the ozone concentration of the air sent out from the ozone generator 10 may be adjusted according to the ozone concentration in the bathtub section 20.

[0031] Furthermore, the housing 11 may include, for example, a switch (not shown) for switching the operation of the pump 12 and the ozone generator 13 ON or OFF, and a power supply unit (not shown) for supplying power to the ozone bubbling device 100. The housing 11 may also be provided with an adjustment button for adjusting the airflow of the pump 12.

[0032] It is preferable to provide ventilation holes (not shown) that allow outside air to be drawn into the inside of the housing 11. It is preferable to provide a filter in these ventilation holes to remove impurities such as dust from the air.

[0033] Figure 3 shows a plan view of the ozone supply unit 30. As shown in Figure 3, the ozone supply unit 30 has a connecting part 31 that is formed to be connectable to a connecting member 40 and a discharge part 32 that is connected to the connecting part 31 and capable of releasing gas containing ozone.

[0034] The connecting portion 31 is formed from a flexible tubular member, such as a rubber hose. The connecting portion 31 has a tip portion 31a that can be connected to the connecting member 40 and a base portion 31b that can be connected to the discharge portion 32.

[0035] The discharge section 32 is formed in the shape of a rectangular plate. The discharge section 32 has a plurality of supply sections 33 on one surface (the top surface) that can supply the ozone-containing gas discharged from the connection section 31.

[0036] Each of the supply units 33 is formed in a hollow cylindrical shape. Each of the supply units 33 is arranged on one surface with a distance between them. In this embodiment, each of the supply units 33 is arranged in 7 rows and 10 columns.

[0037] Figure 4 shows an enlarged plan view of the discharge section 32. As shown in Figure 4, each of the four through-holes 34 are formed on one side of the supply section 33, penetrating that side. Therefore, the internal space of the discharge section 32 is in communication with the outside of the discharge section 32 through the four through-holes 34.

[0038] Each of the adjacent supply units 33 is connected to the others by a plurality of pipes 35. The pipes 35 are connected to the base end 31a of the connection unit 31. Therefore, when gas containing ozone is discharged from the connection unit 31, the gas is released through the pipes 35 and out of the through-holes 34 of the plurality of supply units 33.

[0039] Furthermore, a fixing member (not shown) capable of fixing the discharge section 32 to the bottom surface of the bathtub section 20 may be provided on the back surface (bottom surface) of the surface of the discharge section 32. For example, a suction cup, magnet, double-sided tape, hook-and-loop fastener, etc. may be used as the fixing member.

[0040] The method for improving dermatitis using the ozone bubbling device 100 described above will now be explained. Figure 5 shows the steps of the dermatitis improvement method. As shown in Figure 5, a storage step is performed in which water is stored in the bathtub section 20 of the ozone bubbling device 100 (step S01).

[0041] In step S01, it is preferable to store water in the bathtub section 20 with the ozone supply unit 30 positioned at the bottom. The amount of water stored is not particularly limited, as long as there is a sufficient amount to immerse the affected area in the water. Furthermore, from the viewpoint of supplying ozone-containing gas to the water, it is preferable to store enough water to at least cover the ozone supply unit 30. Note that the water is not limited to cold water and may be adjusted to an appropriate temperature.

[0042] A supply process is performed in which gas containing ozone is supplied from the ozone supply unit 30 to the water stored in the bathtub section 20 (step S02).

[0043] In step S02, the pump 12 and ozone generator 13 are activated by turning on a switch located in the housing 11 of the ozone generation unit 10. When the pump 12 and ozone generator 13 are activated, gas containing ozone is sent from the ozone generation unit 10 to the ozone supply unit 30 via the connecting member 40.

[0044] The ozone supply unit 30 releases the ozone-containing gas sent from the ozone generation unit 10 from the discharge unit 32. When the ozone-containing gas is supplied to the water, the supply continues until a predetermined concentration is reached. When the ozone is bubbled into the water, the concentration of hydrogen peroxide generated based on that ozone is preferably 0.010 to 0.100 ppm, more preferably 0.030 to 0.070 ppm, and more preferably 0.034 to 0.068 ppm.

[0045] There is no established method for measuring the amount of ozone contained in water after bubbling ozone into it. On the other hand, it is possible to measure the amount of hydrogen peroxide derived from the ozone. Therefore, the ozone content of the water will be estimated by measuring the hydrogen peroxide content of the water. It should be noted that, academically, it is believed that the amount of ozone in water is equal to or greater than the amount of hydrogen peroxide derived from the ozone.

[0046] For measuring the amount of hydrogen peroxide, for example, an AS ONE spectrophotometer ASV11D-H can be used. Furthermore, when the ozone concentration (hydrogen peroxide concentration) in the water reaches a predetermined concentration, it is advisable to control the ozone supply to adjust the ozone concentration (hydrogen peroxide concentration) as described above.

[0047] An immersion process is performed in which the affected area of ​​an animal with dermatitis (excluding humans) is immersed in the water of the bathtub section 20 (step S03).

[0048] The time for immersing the affected area in water should be adjusted according to the ozone concentration of the water and the condition of the skin in the affected area. For example, the time for immersing the affected area in water should be 1 to 60 minutes, preferably 5 to 30 minutes, and more preferably 10 to 20 minutes.

[0049] Furthermore, if the affected area is in a part of the body that is difficult to keep immersed in water, such as the head, water containing ozone gas may be applied to the affected area. For example, water containing ozone gas may be applied to the affected area using a shower, bucket, etc.

[0050] The present invention's method for improving dermatitis is particularly effective against allergic dermatitis and seborrheic dermatitis.

[0051] As described above, the ozone bubbling device 100 of the present invention makes it possible to supply ozone-containing gas to the water stored in the bathtub section 20 while bubbling. As a result, ozone can be incorporated into the water stored in the bathtub section 20.

[0052] Furthermore, according to the present invention's method for improving dermatitis and skin condition, the user can improve dermatitis and skin condition by immersing the affected area in the water stored in the bathtub section 20. [Examples]

[0053] [Test Example 1] (Verification of effectiveness against allergic dermatitis) We investigated the effectiveness of a treatment for allergic dermatitis in Maltese dogs.

[0054] The affected areas of patients with allergic dermatitis were regularly immersed in an ozone bubbling device 100 for 10 to 20 minutes, and the progress of the affected areas was observed. The concentration of ozone gas generated by the ozone bubbling device was set to 1.25 to 1.50 ppm.

[0055] Figure 6 shows the condition of the affected area (right side of the neck) before treatment with the ozone bubbling device 100 for dermatitis improvement. Figure 7 shows the condition of the affected area (right side of the neck) after the first treatment with the ozone bubbling device 100 for dermatitis improvement. Figure 8 shows the condition of the affected area (right side of the neck) after the second treatment with the ozone bubbling device 100 for dermatitis improvement. Figure 9 shows the condition of the affected area (right side of the neck) after the third treatment with the ozone bubbling device 100 for dermatitis improvement. The numbers in the figures indicate the date and time the images were taken.

[0056] As shown in Figures 6 to 9, the allergic dermatitis on the right side of the neck showed improvement in symptoms, as the affected area narrowed with each treatment. In addition, gradual hair growth was observed around the affected area after treatment.

[0057] Figure 10 shows the condition of the affected area (caudal flank) before treatment with the ozone bubbling device 100 for dermatitis improvement. Figure 11 shows the condition of the affected area (caudal flank) after the first treatment with the ozone bubbling device 100 for dermatitis improvement. Figure 12 shows the condition of the affected area (caudal flank) after the second treatment with the ozone bubbling device 100 for dermatitis improvement. Figure 13 shows the condition of the affected area (caudal flank) after the third treatment with the ozone bubbling device 100 for dermatitis improvement. The numbers in the figures indicate the date and time the images were taken.

[0058] As shown in Figures 10 to 13, the allergic dermatitis on the caudal ventral region showed improvement in symptoms, as the affected area narrowed with each treatment. In addition, gradual hair growth was observed around the affected area after treatment.

[0059] As described above, it was confirmed that treatment with the ozone bubbling device 100 for improving dermatitis alleviates the symptoms of allergic dermatitis regardless of the location of the affected area. [Test Example 2] (Verification of effectiveness against seborrheic dermatitis) We investigated the effectiveness of a treatment for seborrheic dermatitis in Shih Tzus.

[0060] The affected areas of seborrheic dermatitis were regularly immersed in an ozone bubbling device 100 for 10 minutes, and the progress of the affected areas was observed. The concentration of ozone in the water was kept below 0.1 ppm. The water temperature was kept between 35 and 37°C.

[0061] This procedure was performed once a week, and was stopped after 30 sessions. After that, the patient was observed for several months with only washing performed, and then the procedure was repeated once a week.

[0062] Figure 14 shows the condition of the affected area (left forearm) after the first treatment with the ozone bubbling device 100 for dermatitis improvement. Figure 15 shows the condition of the affected area (left forearm) after the 21st treatment with the ozone bubbling device 100 for dermatitis improvement. Figure 16 shows the condition of the affected area (left forearm) after the 56th treatment with the ozone bubbling device 100 for dermatitis improvement. The numbers in the figures indicate the date and time the images were taken.

[0063] As shown in Figures 14 to 16, the seborrheic dermatitis on the left forearm showed improvement in symptoms, as the affected area narrowed with each treatment. In addition, gradual hair growth was observed around the affected area after treatment.

[0064] Furthermore, according to the observer's records, itching in the affected area, mainly the abdomen, decreased immediately after this treatment was performed. After about 10 treatments, a significant improvement in seborrhea and scaling in the affected area was observed.

[0065] In contrast, when the treatment was discontinued, the seborrhea worsened and itching increased. After resuming the treatment and performing it 10 times, the seborrhea in the affected area improved and the scaling disappeared. After resuming the treatment and performing it 30 times, the rash almost completely healed.

[0066] As described above, the ozone bubbling device 100 for improving dermatitis and the method for improving dermatitis were confirmed to be effective in alleviating symptoms of dermatitis, including allergic dermatitis and seborrheic dermatitis. [Test Example 3] (Verification of the effect on skin condition) Dogs suffering from skin diseases were treated with an ozone bubbling device, and their skin condition was observed before and after treatment. The treatment conditions were the same as in Test Example 2, so the explanation is omitted.

[0067] The study involved 14 dogs aged 6 to 15 years. The dogs consisted of 5 males (2 unneutered) and 9 females (2 unspayed). The breeds included Shih Tzu, Toy Poodle, Pug, Shiba Inu, Chihuahua, French Bulldog, and Miniature Dachshund.

[0068] Of the 14 dogs studied, 10 suffered from seborrheic dermatitis, 6 suffered from pyoderma, and 2 suffered from both seborrheic dermatitis and pyoderma.

[0069] The evaluation of the trial involved the attending physician assessing coat shine, hair loss, desquamation, body odor, and skin balance before, immediately after, and 7 days after the procedure. Coat shine, hair loss, desquamation, body odor, and skin balance were evaluated using the following indicators. These evaluation items correlate with the state of dermatitis (severity of symptoms), and tend to improve as the dermatitis improves. [Coat sheen] The coat's luster was evaluated according to the following criteria. A higher score indicates a better coat condition.

[0070] Evaluation Criteria 1: Very dull 2: Dull 3: Slightly dull 4: Normal 5: Slightly glossy 6: Glossy 7: Very glossy [Hair Removal] The degree of hair loss was evaluated according to the following criteria. A higher score indicates a milder degree of hair loss.

[0071] Evaluation Criteria 1: Very severe 2: Severe 3: Moderately severe 4: Moderate 5: Mild 6: Few 7: None [Debris] The degree of desquamation, also known as "dandruff," was evaluated according to the following criteria. A higher score indicates a milder degree of desquamation.

[0072] Evaluation Criteria 1: Very severe 2: Severe 3: Moderately severe 4: Moderate 5: Mild 6: Few 7: None [body odor] The degree of body odor was evaluated according to the following criteria. A higher score indicates a better degree of body odor.

[0073] Evaluation Criteria 1: Completely unacceptable 2: Unacceptable 3: Acceptable 4: None 5: A slightly pleasant smell 6: Pleasant scent 7: Very pleasant smell [Skin balance (balance between oiliness and dryness)] Skin condition was evaluated from the perspective of the balance between oiliness and dryness. A higher score indicates a better balance in skin condition.

[0074] Evaluation Criteria 1: Very oily or very dry 2: Oily or dry 3: Slightly oily or slightly dry 4: Normal Table 1 shows the average scores for each evaluation item.

[0075] [Table 1] As shown in Table 1, all items, including coat shine, hair loss, desquamation, body odor, and skin balance, were rated higher immediately after the procedure than before. Furthermore, higher ratings were also obtained 7 days after the procedure compared to before the procedure.

[0076] For the average values ​​of each evaluation in Table 1, the ratio of the highest value (%) was calculated using the following formula. The ratio of the highest value (%) is the ratio of the average value to the highest evaluation score, expressed as a percentage. In other words, it is an indicator of the range of evaluations for each item; the higher the ratio of the highest value, the less variation in evaluations can be considered. The values ​​of each highest value (%) are shown in Table 2. Ratio to highest value (%) = (Average value / Highest value) × 100

[0077] [Table 2] As shown in Table 2, the ratio of the highest values ​​(%) immediately after treatment and 7 days after treatment for skin balance is very high, and the data can be evaluated as having little variation in numerical values. In other words, the improvement in skin condition can be obtained regardless of individual differences, especially regarding skin balance.

[0078] For each evaluation in Table 1, the improvement rate (%), which indicates the degree of improvement in skin condition, was calculated using the following formula. The improvement rate (%) is expressed as a percentage of the degree of improvement immediately after treatment and the degree of improvement 7 days after treatment, with the pre-treatment condition as the baseline.

[0079] Immediately after treatment: 100 × (Average value immediately after treatment - Average value before treatment) / Average value before treatment 7 days after treatment: 100 × (Average value 7 days after treatment - Average value before treatment) / Average value before treatment

[0080] [Table 3] As shown in Table 3, improvement was observed immediately after the procedure in all items: coat luster, hair loss, desquamation, body odor, and skin balance. Furthermore, although the improvement rate decreased after 7 days compared to immediately after the procedure, an improvement trend was still observed in coat luster, desquamation, body odor, and skin balance. In particular, the items of body odor and skin balance maintained a high improvement rate (%) even after time had passed since the procedure, indicating a high sustained effect. The improvement rate (%) for hair loss after 7 days was also higher than immediately after the procedure. Therefore, for hair loss, there was a tendency for the effect to appear more easily after a certain period of time had passed since the procedure. Not a single adverse event occurred, and no cases required discontinuation of the study. Based on the above, it can be said that an improvement in skin condition can be expected by using the ozone bubbling device of this embodiment in the procedure. [Explanation of Symbols]

[0081] 100 Ozone bubbling device for improving dermatitis 10 Ozone generation unit 20 Bathtub section

Claims

1. An ozone generating unit that generates a gas containing ozone, A bathtub section formed to be able to store water, The system includes an ozone supply unit that supplies a gas containing the ozone generated by the ozone generation unit to the water stored in the bathtub section, The ozone bubbling device is provided with an ozone supply unit located on the bottom surface of the bathtub, and a discharge unit formed by connecting each of the multiple supply units to each other by piping, from which gas containing ozone can be supplied by bubbling to the water stored in the bathtub.

2. The ozone bubbling device according to claim 1, for use in improving dermatitis or skin conditions.