IL‐17モジュレーターとしてのジシクロプロピルメチル誘導体

JP7891978B2Active Publication Date: 2026-07-17UCB BIOPHARMA SPRL
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Patent Information

Authority / Receiving Office
JP · JP
Patent Type
Patents
Current Assignee / Owner
UCB BIOPHARMA SPRL
Filing Date
2021-11-01
Publication Date
2026-07-17

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Benefits of technology

【0012】 ヒトIL‐17活性の強力なモジュレーターであるだけでなく、本発明による化合物は、他の注目すべき利点も有する。特に、本発明の化合物は、ミクロソーム又は肝細胞のいずれかのインキュベーションで決定されるように、貴重な代謝安定性を示す。

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Abstract

The series of substituted dicyclopropylmethyl derivatives defined herein are potent modulators of human IL-17 activity and are therefore useful in the treatment and / or prevention of a variety of human diseases, including inflammatory and autoimmune diseases.
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