ニロチニブ錠剤

JP7892106B2Active Publication Date: 2026-07-17NIPPON KAYAKU CO LTD
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Patent Information

Authority / Receiving Office
JP · JP
Patent Type
Patents
Current Assignee / Owner
NIPPON KAYAKU CO LTD
Filing Date
2025-06-24
Publication Date
2026-07-17

AI Technical Summary

Benefits of technology

【0008】 本発明によれば、ニロチニブを50質量%以上で含有する医薬錠剤を調製することができ、これにより錠剤が小型化でき、服薬しやすい医薬錠剤を提供することができる。

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Abstract

To provide a pharmaceutical tablet having nilotinib hydrochloride as an active ingredient which is a tablet that can be easily ingested and has high content of nilotinib, preferably to provide a pharmaceutical tablet capable of controlling elution property in pH3.0 buffer solution.SOLUTION: A pharmaceutical tablet using nilotinib hydrochloride as an active ingredient which includes filler, disintegrator and binder inside the tablet. The pharmaceutical tablet has the content of nilotinib of 50 mass% or more. Further, optimizing the disintegrator, binder and filler makes it possible to control tablet collapsibility in pH3.0 buffer solution, and control elution property in a suppressed manner.SELECTED DRAWING: None
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