Kit for tissue pathway occlusion compositions

JP7892947B2Active Publication Date: 2026-07-22ETHICON INC

View PDF 4 Cites 0 Cited by

Patent Information

Authority / Receiving Office: JP · JP
Patent Type: Patents
Current Assignee / Owner: ETHICON INC
Filing Date: 2022-09-16
Publication Date: 2026-07-22

AI Technical Summary

Technical Problem

Current methods for sealing pulmonary pathways after procedures like PTNB and EBUS-TBNA result in significant pneumothorax rates, with existing sealants showing variability and limited effectiveness, and there is a need for a more reliable and efficient method to close larger tissue injuries.

Method used

A kit comprising a first component of a fibrinogen solution and pre-moistened gelatin particles in an aqueous solution, and a second component of a thrombin solution and dry gelatin particles, which are mixed together to form a fluid and crosslinkable composition for sealing pulmonary pathways.

Benefits of technology

The composition effectively seals pulmonary pathways, reducing pneumothorax risk and promoting rapid hemostasis, with a sealant that can be easily applied and crosslinks within 30 seconds, providing a durable mechanical seal.

✦ Generated by Eureka AI based on patent content.

Smart Images

Figure 0007892947000004
Figure 0007892947000005
Figure 0007892947000006

Patent Text Reader

Abstract

The present invention provides a kit for preparing a composition for sealing a pulmonary passage comprising: (a) a first component comprising (i) a fibrinogen solution and (ii) pre-wet gelatin particles in an aqueous solution; and (b) a second component comprising (i) a thrombin solution and (ii) dry gelatin powder, wherein the first and second components are stored separately and are configured to be mixed together to form a flowable and crosslinkable composition. The composition may be used to seal a tissue passage, such as a pulmonary tissue passage.

Need to check novelty before this filing date? Find Prior Art