composition containing surfactant

Abstract

To provide a novel composition (a composition containing a surfactant).SOLUTION: A composition includes a dimethicone (a), ethanol, and water. The dimethicone (a) is a PEG / PPG-40 to 70 / 40 to 70 dimethicone and / or a PEG-20 to 40 dimethicone.SELECTED DRAWING: None

Description

[Technical Field]

[0001] This invention relates to novel compositions (compositions containing surfactants), etc. [Background technology]

[0002] While various forms of disinfectants, such as liquid, gel, and foam formulations, are used for hand sanitizers and other disinfectants, foam formulations are sometimes preferred due to their less dripping properties and better usability. Foam formulations use formulations that exhibit foaming properties upon use. Ethanol is also widely used as a disinfectant. [Prior art documents] [Patent Documents]

[0003] [Patent Document 1] Japanese Patent Publication No. 2017-71574 [Overview of the Initiative] [Problems that the invention aims to solve]

[0004] The object of the present invention is to provide novel compositions (compositions containing surfactants), etc. [Means for solving the problem]

[0005] In ethanol-containing formulations, sufficient foaming properties may not be obtained depending on the type of surfactant used, and the use of silicone-based surfactants is being considered (Patent Document 1, etc.). However, silicone-based surfactants decompose under acidic or basic conditions, resulting in problems such as the loss of foaming properties, making it difficult to impart foaming properties to ethanol-containing formulations. Under these circumstances, the inventors discovered that dimethicone having a specific structure exhibits good foaming properties when combined with ethanol, even under acidic conditions. Through further diligent research, they completed the present invention.

[0006] In other words, the present invention relates to the following inventions, etc. [1] A composition comprising dimethicone (a), ethanol, and water, wherein dimethicone (a) is PEG / PPG-40~70 / 40~70 dimethicone and / or PEG-20~40 dimethicone. [2] The composition according to [1], wherein dimethicone (a) is PEG / PPG-50~60 / 50~60 dimethicone and / or PEG-20~40 dimethicone. [3] The composition according to [1] or [2], wherein dimethicone (a) comprises one or more selected from the group consisting of PEG / PPG-53 / 54 dimethicone and PEG-32 methyl ether dimethicone. [4] The composition according to [1] or [2], wherein dimethicone (a) comprises PEG / PPG-53 / 54 dimethicone. [5] A composition according to any one of [1] to [4], comprising 0.1 to 10 w / v% of dimethicone (a) relative to the whole composition. [6] A composition according to any one of [1] to [5], comprising ethanol at a concentration of 40 v / v% or more relative to the entire composition. [7] A composition according to any one of [1] to [6], wherein the pH is 3 to 5. [8] A composition according to any one of [1] to [7], further comprising a pH adjuster. [9] A foaming composition as described in any of [1] to [8].

[10] A composition according to any one of the following [1] to [9], which is for use in pump-type foam formulations, squeeze-type foam formulations, or aerosol foam formulations. [Effects of the Invention]

[0007] According to the present invention, a novel composition (a composition containing a surfactant) can be provided. Such a composition can exhibit good foaming properties. In particular, it can exhibit good foaming properties even under acidic conditions.

[0008] One aspect of the composition of the present invention can maintain good foaming properties even after long-term storage.

[0009] One aspect of the composition of the present invention is difficult to decompose even under acidic conditions. Therefore, such a composition is likely to maintain a colorless and transparent appearance.

[0010] One aspect of the composition of the present invention can be in a dissolved state or a non-separated state. Such a composition can be suitably used for pump-type foam formulations.

Mode for Carrying Out the Invention

[0011] [Composition] The composition (formulation) of the present invention contains a specific dimethicone (a), ethanol, and water.

[0012] Dimethicone (a) Dimethicone (dimethylpolysiloxane) (a) may have dimethylsiloxane units (―[Si(CH3)2―O]― units) and oxyethylene units (hereinafter, also simply referred to as "PEG units") and / or oxypropylene units (hereinafter, also simply referred to as "PPG units"). In dimethicone (a), the bonding form and bonding site of each unit are not particularly limited. For example, PEG units and PPG units may be bonded to (or substituted for) a dimethylsiloxane unit (for example, a methyl group of a dimethylsiloxane unit), or may be bonded to (or substituted for) the end of dimethicone (a). Note that PEG units and PPG units may be bonded to (or substituted for) both the dimethylsiloxane unit and the end of dimethicone (a), or may be bonded to (or substituted for) either one of them. When PEG or PPG units are bound to the ends of dimethicone(a), the extent to which they are bound to the ends is irrelevant; for example, they may be bound to one end of dimethicone(a) or to both ends.

[0013] When PEG units or PPG units are bonded to dimethylsiloxane units, they may be substituted for hydrogen atoms in the (side chain) methyl groups of the dimethylsiloxane units. When PEG units or PPG units are bonded to the ends of dimethicone(a), they may be substituted for, for example, a hydrogen atom of a (terminal) methyl group, or for part of another group. PEG units and PPG units may be directly bonded to the ends of dimethylsiloxane units or dimethicone(a), or they may be bonded via linking groups.

[0014] When PEG units or PPG units are linked via a linking group, the linking group is not particularly limited, but may be, for example, a hydrocarbon group, an ether linkage, or a group having an ether linkage. Examples of hydrocarbon groups include aliphatic hydrocarbon groups {for example, alkylene groups [for example, linear (straight-chain or branched-chain) alkylene groups (for example, methylene group, ethylene group, propylene group, isopropylene group, butylene group, isobutylene group, etc. C 1-20 Saturated aliphatic hydrocarbon groups such as alkylene groups; alkenylene groups [for example, linear (straight-chain or branched-chain) alkenylene groups (for example, etenylene, propenylene, butenylene, etc. C 2-20 Examples include unsaturated aliphatic hydrocarbon groups such as alkenylene groups, preferably saturated aliphatic hydrocarbon groups, and more preferably linear alkylene groups (e.g., C 1-10 Alkylene group, C 1-5 (Alkylene group, etc.) etc. ramen.

[0015] Dimethicone (a) may preferably have PEG units and PPG units, or have PEG units, etc.

[0016] Typical examples of dimethicone (a) include, for example, PEG / PPG-25~70 / 30~70 dimethicone and PEG-20~40 dimethicone.

[0017] PEG / PPG-x / y dimethicone is a compound in which PEG units and PPG units are bonded to the dimethylsiloxane units and / or terminals of dimethicone, where x represents the degree of polymerization (average degree of polymerization) of the PEG units and y represents the degree of polymerization (average degree of polymerization) of the PPG units.

[0018] For example, PEG / PPG-53 / 54 dimethicone may be a dimethicone containing PEG units with a degree of polymerization of 53 and PPG units with a degree of polymerization of 54. Similarly, PEG-20~40 dimethicone may be a dimethicone containing PEG units with a degree of polymerization of 20~40.

[0019] Examples of PEG / PPG-25~70 / 30~70 dimethicone include PEG / PPG-40~70 / 40~70 dimethicone, PEG / PPG-25~40 / 30~40 dimethicone, and preferably PEG / PPG-40~70 / 40~70 dimethicone (for example, PEG / PPG-45~65 / 45~65 dimethicone, PEG / PPG-50~60 / 50~60 dimethicone).

[0020] PEG-20~40 dimethicone may preferably be PEG-25~40 dimethicone (for example, PEG-25~35 dimethicone), etc.

[0021] An example of PEG / PPG-40~70 / 40~70 dimethicone, in which PEG units and PPG units are bonded to a dimethylsiloxane unit, may be one having the unit (or structure) shown in the following formula (1).

[0022] [ka] (In the formula, m and n are integers of 1 or more, R1 represents a linking group, R2 represents a hydrogen atom or substituent, x represents 40 to 70, y represents 40 to 70, and X and Y represent substituents.)

[0023] In equation (1), m and n can be integers greater than or equal to 1. m may be, for example, 1 to 1000, preferably 20 to 1000, etc. n may be, for example, 1 to 500, preferably 1 to 100, etc.

[0024] In equation (1), x and y may differ for each n [that is, for each unit shown in equation (1A) below (hereinafter also simply referred to as the "equation (1A)" unit)]. For x, the average value (average degree of polymerization) of x should be between 40 and 70, and for y, the average value (average degree of polymerization) of y should be between 40 and 70.

[0025] [ka]

[0026] R1 and R2 may differ for each unit of formula (1A).

[0027] Note that in formula (1), "―[dimethylsiloxane unit] m [Equation (1A) Unit] n The "-" does not indicate the bonding order of the dimethylsiloxane unit and the (1A) unit, but simply means that the ratio of the dimethylsiloxane unit to the (1A) unit is m:n.

[0028] Furthermore, in the units of formula (1) and formula (1A), "(C2H4O) x (C3H6O) y This does not mean the bonding order of (C2H4O) units and (C3H6O) units, but rather that the ratio of (C2H4O) to (C3H6O) is x:y, although it is often a block structure of (C2H4O) units and (C3H6O) units.

[0029] Examples of the linking group in R1 include the linking groups exemplified above, such as a hydrocarbon group, an ether bond, a group having an ether bond, and the like.

[0030] The substituent in R2 is not particularly limited. For example, it may be a hydrocarbon group, an alkyloxy group (e.g., C 1-20 alkyloxy group), a hydroxy group, and the like. Examples of the hydrocarbon group include an aliphatic hydrocarbon group {e.g., an alkyl group [e.g., a chain (linear or branched) alkyl group (e.g., a methyl group, an ethyl group, a propyl group, an isopropyl group, a butyl group, an isobutyl group, etc., C 1-20 alkyl group), etc., a saturated aliphatic hydrocarbon group; an alkenyl group [e.g., a chain (linear or branched) alkenyl group (e.g., a vinyl group, a propenyl group, an isopropenyl group, a butenyl group, an isobutenyl group, etc., C 2-20 alkenyl group)], etc., an unsaturated aliphatic hydrocarbon group}, etc. Preferably, it may be a saturated aliphatic hydrocarbon group, etc., and more preferably a chain alkyl group (e.g., C 1-10 alkyl group, C 1-5 alkyl group, etc.).

[0031] X and Y are not particularly limited. For example, they may be the substituents exemplified in R2 above, or may be substituents via a linking group (e.g., a group having a ―Si-bond or a ―O-Si-bond, etc.). X and Y may be the same or different.

[0032] As an example of PEG-20~40 dimethicone in which a PEG unit is bonded to a dimethylsiloxane unit, it may be one having a unit (or structure) represented by the following formula (2), etc. [[ID=3__

[0033]

Chemical formula

[0034] In equation (2), m, n, R1, and R2 may be the same as m, n, R1, and R2 in the example equation (1) above.

[0035] In equation (2), z may differ for each n [that is, for each unit shown in equation (2A) below (hereinafter also simply referred to as the "equation (2A)" unit)]. z should have an average value (average degree of polymerization) of 20 to 40.

[0036] [ka]

[0037] R1 and R2 may differ for each unit of formula (2A).

[0038] Note that in formula (2), "―[dimethylsiloxane unit] m [Equation (2A) Unit] n The "-" symbol does not indicate the bonding order of the dimethylsiloxane unit and the (2A) unit, but simply means that the ratio of the dimethylsiloxane unit to the (2A) unit is m:n.

[0039] X and Y are not particularly limited and may be substituents as exemplified in R2 of formula (1) above, or substituents via linking groups (e.g., groups having -Si- bonds or -O-Si- bonds). X and Y may be the same or they may be different.

[0040] The method for measuring (and calculating) the degree of polymerization of oxyethylene units and oxypropylene units in dimethicone (a) is not particularly limited, and conventional methods may be used. for example, 1The degree of polymerization may also be calculated from the ratio of the integral value of the peak of a specific group in an oxyethylene unit (―[O―(CH2)2]―) or an oxypropylene unit (―[O―CH(CH3)CH2]―) measured using 1H-NMR, to the integral value of the peak of a specific group derived from the "―[Si(CH3)2O]―" unit. For example, if dimethicone(a) is PEG / PPG-dimethicone, the degree of polymerization of the oxyethylene unit and the oxypropylene unit may be calculated as described in the examples below. If dimethicone(a) is PEG-dimethicone, the integral value of the "-(CH2)2-" peak in the oxyethylene unit (-[O-(CH2)2]-) and the "-Si-" derived from the "-[Si(CH3)2O]-" unit are used. CH The degree of polymerization may also be calculated from the ratio of the integral value of the "-CH2-" peak in "2-".

[0041] When dimethicone(a) contains PEG units and PPG units, the copolymerization form of each unit is not particularly limited and may be a random structure or a block structure. The block structure is not particularly limited and may be, for example, a diblock (PEG / PPG), a triblock (PEG / PPG / PEG or PPG / PEG / PPG), and preferably a diblock.

[0042] Typical examples of dimethicone (a) include PEG / PPG-53 / 54 dimethicone and PEG-32 methyl ether dimethicone.

[0043] For dimethicone (a), commercially available products may be used, such as DBP-732 (manufactured by Gelest) or KF-6004 (manufactured by Shin-Etsu Chemical Co., Ltd.).

[0044] Furthermore, dimethicone (a) may be used alone or in combination of two or more types.

[0045] The proportion of dimethicone (a) in the composition may be, for example, 0.01 w / v% or more (e.g., 0.05 w / v% or more), preferably 0.1 w / v% or more (e.g., 0.3 w / v% or more), or, for example, 20 w / v% or less (e.g., 15 w / v% or less), preferably 10 w / v% or less (e.g., 5 w / v% or less, 3 w / v% or less, 1 w / v% or less).

[0046] Furthermore, you may choose a range by combining these ranges (upper and lower limits) as appropriate (for example, 0.01 to 15 w / v%, 0.1 to 1 w / v%, etc.).

[0047] ethanol There are no particular limitations on the type of ethanol used; commercially available products can be used. The concentration of ethanol used is not particularly limited; for example, 95 v / v% ethanol can be used.

[0048] The proportion of ethanol in the composition may be, for example, 40 v / v% or more (e.g., 45 v / v% or more, 60 v / v% or more, 65 v / v% or more, etc.) relative to the entire composition, from the viewpoint of disinfection effect, etc., or it may be less than 100 v / v% (e.g., 99 v / v% or less, 95 v / v% or less, 90 v / v% or less, 85 v / v% or less, 80 v / v% or less, 75 v / v% or less, 70 v / v% or less, etc.).

[0049] You may also select a range by combining these ranges (upper and lower limits) as appropriate (for example, 40-95 v / v%, 45-90 v / v%, etc.).

[0050] The ratio of dimethicone(a) to ethanol in the composition is not particularly limited, but the mass ratio of dimethicone(a) to ethanol may be, for example, 1:30 to 1:50, preferably 1:30 to 1:40, and more preferably 1:30 to 1:35.

[0051] water The water used is not particularly limited and may include, for example, tap water, purified water, or deionized water.

[0052] The proportion of water in the composition may be, for example, 10 w / v% or more (e.g., 15 w / v% or more, 20 w / v% or more, 25 w / v% or more, etc.) or 60 w / v% or less (e.g., 55 w / v% or less, 50 w / v% or less, 45 w / v% or less, 40 w / v% or less, etc.) relative to the total composition.

[0053] You may also choose a range by combining these ranges (upper and lower limits) as appropriate (for example, 10-60 w / v%, 25-50 w / v%, etc.).

[0054] Other ingredients The composition may contain other components besides dimethicone (a), ethanol, and water. Other ingredients are not limited to those commonly used in disinfectants and foam formulations. Other ingredients include, for example, pH adjusters, surfactants not belonging to the category of dimethicone (a), non-aqueous solvents other than ethanol, disinfectants (antibacterial agents, germicidal agents, bactericidal agents), viscosity modifiers (viscosity modifiers, polymer thickeners, etc.), foaming agents, preservatives, deodorants, fragrances, stabilizers, improvers, plasticizers, solubilizers, reducing agents, buffers, volatilization aids, suspension agents, wetting modifiers, fillers, defoamers, fragrances, colorants, isotonic agents, softeners, emulsifiers, foaming agents, skin protectants, flotation agents, dispersants, propellants, fragrances, rust inhibitors, preservatives, solvents, solubilizers, etc.

[0055] Furthermore, other ingredients may possess multiple functions.

[0056] Examples of other such components include, for example, pH adjusters [e.g., inorganic acids (phosphoric acid, hydrochloric acid, sulfuric acid, etc.), organic acids (lactic acid, sodium lactate, citric acid, sodium citrate, succinic acid, sodium succinate and their hydrates, etc.), inorganic bases (potassium hydroxide, sodium hydroxide, etc.), organic bases (triethanolamine, diisopropanolamine, triisopropanolamine, etc.)], nonionic surfactants [e.g., polyoxyethylene fatty acid esters, polyglycerin fatty acid esters, PEG [polyethylene glycol or polyoxyethylene (POE)] hydrogenated castor oil (POE hydrogenated castor oil), POE castor oil, sorbitan fatty acid esters, POE sorbitan fatty acid esters, polyoxyethylene polyoxypropylene (POP) glycol, POE alkyl ethers, POE-POP]. Alkyl ethers, POE alkylphenyl ethers, etc., amphoteric surfactants [e.g., carboxybetaine type (e.g., alkyldimethylaminoacetic acid betaine, fatty acid amidopropyl betaine), sulfobetaine type (e.g., alkyl sulfobetaine, alkyl hydroxysulfobetaine), imidazoline betaine type (e.g., alkyl carboxymethylhydroxyethylimidazolinium betaine), etc., betaine-type amphoteric surfactants], cationic surfactants (e.g., cetylpyridinium chloride, benzethonium chloride, decalinium chloride, didecyldimethylammonium chloride, N-coconut oil fatty acid acyl-L-arginine ethyl DL-pyrrolidone carboxylate, etc.), lower alcohols other than ethanol (e.g., isopropanol, etc.), polyhydric alcohols (e.g., glycerin, 1,Examples include 3-butylene glycol, propylene glycol, polyethylene glycol (macrogol), isoprene glycol, dipropylene glycol, etc., polysaccharides or their derivatives (e.g., hydroxyethylcellulose, hydroxypropylcellulose, hydroxypropylmethylcellulose, hydrophobized hydroxypropylmethylcellulose, carboxymethylcellulose (sodium carboxymethylcellulose), guar gum, carrageenan, locust bean gum, xanthan gum, etc.), disinfectants (antibacterial agents, germicidal agents, bactericidal agents) (e.g., oranexidine, triclosan, trichlorocarbanilide, chlorhexidine hydrochloride, benzalkonium chloride, benzethonium chloride, cetylpyridinium chloride, benzalkonium alkyl phosphate, isopropylmethylphenol, benzoic acid, iodine preparations, sodium hypochlorite, chlorite, chlorhexidine gluconate, acrinol, alcohols, hydrogen peroxide, phenols, etc.).

[0057] Other ingredients may be used individually or in combination of two or more.

[0058] If the composition contains other components, the proportion of those other components can be appropriately selected depending on their type, intended use, etc.

[0059] The proportion of other components (total amount) in the composition may be, for example, 20 w / v% or less (e.g., 15 w / v% or less, 10 w / v% or less, 5 w / v% or less, 3 w / v% or less, 2 w / v% or less, 1 w / v% or less, 0.5 w / v% or less) relative to the whole composition, or for example, 0.001 w / v% or more (e.g., 0.01 w / v% or more, 0.1 w / v% or more).

[0060] Furthermore, you may choose a range by combining these ranges (upper and lower limits) as appropriate (for example, 0.001 to 20 w / v%, 0.01 to 1 w / v%, etc.).

[0061] The pH of the composition is not particularly limited, but may be, for example, 2 to 6, preferably 3 to 5.

[0062] [Form / manufacturing method] The form (properties) of the composition of the present invention is not particularly limited, but it may usually be in liquid form. The liquid composition may be a solution, suspension, emulsion, etc., depending on the components of the composition. A liquid composition may be one in which the components constituting the composition are dissolved or not separated.

[0063] The composition (the composition at the time of use) may be in the form of a foam, mist, etc. That is, the composition may be foaming and may become foamy or misty when dispensed from the container.

[0064] The composition can be obtained by mixing the components. The mixing may involve mixing all components at once, or by mixing two or more pre-prepared components first, and then mixing the remaining components. The mixing method (manufacturing method) is not particularly limited, and conventional methods can be used.

[0065] [Application] The uses of the compositions of the present invention are not particularly limited, but they can be used, for example, as disinfectants, antibacterial agents, germicides, sterilizing agents, antiviral agents (including non-enveloped viruses, etc.), pharmaceuticals, etc. Furthermore, the compositions of the present invention can be suitably used for pump-type foam formulations, squeeze-type foam formulations, aerosol-type foam formulations, etc.

[0066] [How to use] The form of use (method of application) of the composition of the present invention can be appropriately selected depending on the purpose of use of the composition, etc. For example, it can be used by applying it to the target (application) area.

[0067] One specific application method is application (adhesion) to the target area. For example, the composition may be dispensed from a container and applied as a foam. The composition may be contained in a suitable container. The container can be selected according to the application method.

[0068] For example, the composition may be applied in a foamy form by placing it in a foam-forming container (e.g., a foam bottle, a squeeze bottle, etc.) and dispensing it from the container. Alternatively, the composition may be placed in a spray container (spray bottle) together with a propellant (for example, compressed gas such as LPG), and applied in the form of a mist or foam by spraying (jetting) or discharging from the container.

[0069] The amount of the composition to be applied (used) varies depending on the area of ​​application, the condition of the skin, and the age of the person applying it. For example, in the case of hand disinfection, the amount used per application may be around 1 to 10 mL.

[0070] The composition may be applied to healthy individuals or to individuals with various diseases (or symptoms). [Examples]

[0071] The present invention will be described in more detail below with reference to examples, but the present invention is not limited thereto.

[0072] sample The following surfactants were used. PEG / PPG-53 / 54 Dimethicone (Product name DBP-732, Gelest) PEG-32 Methyl Ether Dimethicone (Product Name KF-6004, Shin-Etsu Chemical Co., Ltd.) PEG-10 Dimethicone (Product Name: Silsoft 860, Momentive) PEG-12 Dimethicone (Product name: Silsoft 870, Momentive)

[0073] Measurement of the degree of polymerization Since the degree of polymerization of PEG and PPG in Gelest's surfactants was unknown, it was measured using the following method. A JEOL Ltd.-made (JNM-ECZ400S FT-NMR) nuclear magnetic resonance spectrometer was used. The measurement conditions were: nuclide: 1H, number of scans: 64, solvent: deuterated chloroform, sample concentration: approximately 10 mg / mL. The chloroform in deuterated chloroform was used as the reference peak for the chemical shift value (7.26 ppm), and the "-Si-" at the base of the linking group R1 around 0.5 ppm was used. CH The "-CH2-" peak in "2-R1-" was used as the reference peak (2H) for the integral ratio. The degree of polymerization of PPG is around 1.14 ppm, where PPG has a "-O-CH( CH 3) The integral ratio of the "(CH3)" peak in "CH2-" was divided by 3 (e.g., when the integral ratio of the peak around 1.14 ppm is 162.82, the degree of polymerization of PPG = 162.82 ÷ 3 ≈ 54.3). The degree of polymerization of PEG is around 3.3-3.8 ppm, where PEG has the "-O-" CH 2 CH The "-CH2CH2-" peak in "2-" and the "-O-" peak in PPG. CH (CH3) CH The integral ratio of the "-CH-CH2-" peak in "2-" was subtracted from the integral ratio derived from PPG, and the remainder was divided by 4 (for example, when the integral ratio of the peak around 3.3~3.8 ppm is 373.73 and the degree of polymerization of PPG is 54.3, the degree of polymerization of PEG = {373.73 - (3 × 54.3)} ÷ 4 ≈ 52.7).

[0074] pH measurement A pH meter manufactured by Horiba, Ltd. (F-22) was used. The pH meter was calibrated with a pH standard solution, and then the pH was measured.

[0075] Foaming test 50 mL of the test sample was placed in a 50 mL screw-cap vial (Laboran Screw-Cap Vial No. 7, AS ONE Corporation), and the foaming properties were visually confirmed after vigorously shaking for 10 seconds.

[0076] (Examples 1-7) The compositions were obtained by mixing each component (dimethicone, ethanol, phosphoric acid, and water) according to the formulations described in Tables 1 and 2. In addition, after dissolving the dimethicone in ethanol, phosphoric acid was added to achieve the pH levels shown in Table 1, and then water was added to make a total volume of 100 mL.

[0077] (Comparative Examples 1-6) The compositions were obtained by mixing each component (dimethicone, ethanol, phosphoric acid, and water) according to the formulations described in Table 3. Specifically, after dissolving the dimethicone in ethanol, phosphoric acid was added to achieve the pH levels shown in Table 3, and then water was added to make a total volume of 100 mL.

[0078] (Reference examples 1~4) The compositions were obtained by mixing each component (dimethicone, ethanol, and water) according to the formulations described in Tables 1-3. Note that after dissolving the dimethicone in ethanol, water was added to make a total volume of 100 mL.

[0079] The compositions of Examples 1-7, Comparative Examples 1-6, and Reference Examples 1-4 were tested for foaming properties immediately after preparation using the method described above, and all compositions exhibited foaming properties (they produced foam).

[0080] Furthermore, each composition was stored at 50°C, and its foaming properties were confirmed using the method described above. The presence or absence of foaming was evaluated according to the following criteria. [Presence or absence of air bubbles] Foaming properties: Shows foaming equivalent to the example shown. No foaming ability: Shows less foaming than the reference example, or shows no foaming at all.

[0081] Based on the above criteria, the presence or absence of air bubbles was checked weekly during the storage period, and the stability of foaming properties was evaluated according to the following criteria. [Stability of foaming properties] ◎: It retained its foaming properties even after 4 weeks of storage. ○: The foaming ability was lost after 3-4 weeks of storage. △: The foaming ability was lost after 2-3 weeks of storage. ▲: The foaming ability was lost after 1-2 weeks of storage. ×: The foaming ability was lost in less than one week of storage.

[0082] The results are shown in Tables 1-3. In Tables 1-3, ethanol (95) represents 95 v / v% ethanol.

[0083] [Table 1]

[0084] [Table 2]

[0085] [Table 3]

[0086] As shown in Tables 1-3, the examples exhibited good foaming properties, similar to the reference examples, and the stability of the foaming properties was also good. Furthermore, a neutral (or near-neutral) solution in which the surfactant does not decompose was used as a reference example to determine the foaming properties.

[0087] When each of the compositions in the examples was placed in a foaming bottle (pump-type foamer) and dispensed from the foaming bottle, all of the compositions formed good foam.

[0088] Each of the compositions in the examples was filled into an aerosol can with a propellant (LPG) in a composition:propellant (mass ratio) of 9:1, and then dispensed from the aerosol can. All compositions formed foam. [Industrial applicability]

[0089] According to the present invention, it is possible to provide compositions and the like that are useful as disinfectants (especially foaming disinfectants).

Claims

1. A disinfectant composition comprising dimethicone (a), ethanol, and water, wherein dimethicone (a) is PEG / PPG-40 to 70 / 40 to 70 dimethicone and / or PEG-20 to 40 dimethicone, and the pH is 3 to 5.

2. The composition according to claim 1, wherein dimethicone (a) comprises PEG / PPG-53 / 54 dimethicone.

3. The composition according to claim 1 or 2, wherein dimethicone (a) comprises PEG-32 methyl ether dimethicone.

4. The composition according to claim 1 or 2, comprising only dimethicone (a) as a surfactant.

5. The composition according to claim 1 or 2, comprising 0.1 to 10 w / v% of dimethicone (a) relative to the whole composition.

6. The composition according to claim 1 or 2, comprising 40 v / v% or more of ethanol relative to the whole composition.

7. The composition according to claim 3, comprising only dimethicone (a) as a surfactant.

8. The composition according to claim 3, comprising 0.1 to 10 w / v% of dimethicone (a) relative to the whole composition.

9. The composition according to claim 3, comprising 40 v / v% or more of ethanol relative to the whole composition.

10. A disinfectant composition comprising dimethicone (a), ethanol, and water, wherein dimethicone (a) is PEG / PPG-53 / 54 dimethicone in an amount of 0.1 to 10 w / v% of the whole composition, and ethanol is 40 v / v% or more of the whole composition.

11. A disinfectant composition comprising dimethicone (a), ethanol, and water, wherein dimethicone (a) is PEG-32 methyl ether dimethicone in an amount of 0.1 to 10 w / v% of the whole composition, and ethanol is 40 v / v% or more of the whole composition.

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