Simulated urine odor composition and evaluation method

Abstract

To provide an artificial urine odor composition that produces a urine odor accurately mimicking the real odor of urine, and a method for evaluating a deodorizing effect using the artificial urine odor composition.SOLUTION: An artificial urine odor composition includes phenylacetic acid.SELECTED DRAWING: None

Description

Technical Field

[0001] The present invention relates to a simulated urine odor composition simulating urine odor, and a method for evaluating a deodorizing effect using the simulated urine odor composition.

Background Art

[0002] Various techniques for suppressing urine odor have been proposed conventionally. For example, Patent Document 1 discloses a urine odor inhibitor for suppressing urine odor. In developing the above urine odor inhibitor, it is necessary to evaluate the deodorizing effect of the urine odor inhibitor against urine odor. However, using actual human urine when evaluating the deodorizing effect is not preferable from the viewpoints of individual differences in urine components (and thus urine odor) and hygiene.

[0003] Therefore, Patent Document 2 discloses a pseudo urine odor composition simulating urine odor. In the technique of Patent Document 2, a phenol compound having 6 to 10 carbon atoms and trimethylamine are contained in a predetermined mass ratio to simulate urine odor.

Prior Art Documents

Patent Documents

[0004]

Patent Document 1

Patent Document 2

Summary of the Invention

Problems to be Solved by the Invention

[0005] However, the technology described in Patent Document 2 produces a strong putrid odor rather than a urine odor, and there is room for improvement in terms of closely resembling the actual urine odor. Furthermore, the odor of urine varies depending on the location and environment in which the urine adheres. Patent Document 2 simulates the urine odor generated from a toilet with scattered urine and the odor of a used diaper. Therefore, the technology described in Patent Document 2 differs significantly from the actual urine odor generated from urine that has adhered to clothing fibers for an extended period of time. Taking these circumstances into consideration, the present invention provides a simulated urine odor composition that appropriately simulates the actual urine odor, and a method for evaluating the deodorizing effect using the simulated urine odor composition. [Means for solving the problem]

[0006] [1] The simulated urine odor composition according to the present invention contains phenylacetic acid.

[0007] [2] The simulated urine odor composition according to [1], comprising p-cresol, wherein the mass ratio of the p-cresol content to the phenylacetic acid content (p-cresol / phenylacetic acid) is 2 / 8 to 8 / 2.

[0008] [3] Aminoacetophenone It includes, and the amount of phenylacetic acid Aminoacetophenone Mass ratio of the content ( Aminoacetophenone The simulated urine odor composition described in [1] or [2], wherein the phenylacetic acid is 1 / 9 to 5 / 5.

[0009] An evaluation method for evaluating the deodorizing effect of a target object against urine odor using a simulated urine odor composition described in any of [4], [1], to [3].

[0010] [5] The evaluation method of [4] wherein the object is a fiber for underwear. [Effects of the Invention]

[0011] The simulated urine odor composition according to the present invention can generate a urine odor that appropriately simulates the actual urine odor. In particular, it can generate a urine odor that appropriately simulates the actual urine odor that arises from urine that has been adhering to underwear (pants) for a period of time.

[0012] According to the evaluation method of the present invention, since a simulated urine odor composition that appropriately simulates the actual urine odor is used, the deodorizing effect on urine odor can be appropriately evaluated. [Modes for carrying out the invention]

[0013] The simulated urine odor composition according to the present invention is a composition that simulates the actual odor of human urine. Here, the inventors of the present invention analyzed actual urine odor in order to make the urine odor generated from the simulated urine odor composition as close to that of actual urine as possible. The inventors of the present invention hold a national qualification as odor assessors.

[0014] Specifically, we first extracted 22 common components from the following reports on urine odor1-4). 1) Hirohiko Ishida, Yuki Tazo, Ichiro Mori, Tatsuya Yamada, Hiroko Matsufusa, On reducing odors throughout a nursing care facility by focusing on the source of urine odor, Journal of the Japan Society for Odor and Aroma Environment, 2016, 49(2), 129-138. 2) Hiroyuki Kato, Malodorous substances and their generation mechanisms, Buildings and Environment, 2017, 159, 15-23. 3)Mika Shirasu, Kazushige Tohara, The scent of disease:volatile organic compounds of the human body related to disease and disorder, J. Biochem, 2011, 150(3), 257-266 4)Myriam Troccaz, Yvan Niclass, Pauline Anziani, Christian Starkenmann, The influence of thermal reaction and microbial transformation on the odour of human urine, Flavor Fragr.J. 2013, 28, 200-211

[0015] However, it had not been confirmed which of the 22 extracted components significantly influenced the urine odor. Therefore, the inventors of this invention smelled each of the 22 components and identified 5 to 10 components that closely resembled the urine odor. As a result, it was newly discovered that phenylacetic acid, in particular, contributes significantly to the urine odor. Based on these findings, the following simulated urine odor composition was devised.

[0016] Specifically, the simulated urine odor composition according to the present invention is characterized by containing phenylacetic acid. By containing phenylacetic acid, the simulated urine odor composition can generate a urine odor that appropriately simulates the actual urine odor.

[0017] From the viewpoint of closely resembling the actual urine odor, the phenylacetic acid content in the simulated urine odor composition is, for example, 10 to 100% by mass, preferably 20 to 80% by mass.

[0018] The simulated urine odor composition preferably contains p-cresol in addition to phenylacetic acid. The inclusion of p-cresol in the simulated urine odor composition allows for the generation of a urine odor that more accurately simulates the actual urine odor.

[0019] From the viewpoint of closely resembling the actual urine odor, the p-cresol content in the simulated urine odor composition is, for example, 10 to 90% by mass, preferably 20 to 80% by mass.

[0020] The mass ratio of the content of p-cresol to the content of phenylacetic acid (p-cresol / phenylacetic acid) is, for example, 0 / 10 to 9 / 1, preferably 2 / 8 to 8 / 2. By setting the mass ratio (p-cresol / phenylacetic acid) within the above range, an odor closer to the actual urine odor can be generated. In particular, it is possible to appropriately simulate the actual urine odor generated from urine adhering to underwear and having elapsed time.

[0021] Furthermore, the simulated urine odor composition preferably contains Aminoacetophenone . By the simulated urine odor composition containing Aminoacetophenone , an odor that more appropriately simulates the actual urine odor can be generated.

[0022] The content of Aminoacetophenone in the simulated urine odor composition is, from the viewpoint of approaching the actual urine odor, for example, 10 to 90% by mass, preferably 10 to 70% by mass.

[0023] The mass ratio of the content of Aminoacetophenone to the content of phenylacetic acid ( Aminoacetophenone / phenylacetic acid) is, for example, 1 / 9 to 9 / 1, preferably 1 / 9 to 5 / 5. By setting the mass ratio ( Aminoacetophenone / phenylacetic acid) within the above range, an odor closer to the actual urine odor can be generated. In particular, it is possible to appropriately simulate the actual urine odor generated from urine adhering to underwear and having elapsed time.

[0024] The mass ratio of the content of Aminoacetophenone to the content of p-cresol ( Aminoacetophenone / p-cresol) is, for example, 1 / 9 to 9 / 1, preferably 1 / 9 to 5 / 5. By setting the mass ratio ( Aminoacetophenone / phenylacetic acid) within the above range, an odor closer to the actual urine odor can be generated. In particular, it is possible to appropriately simulate the actual urine odor generated from urine adhering to underwear (typically pants) and having elapsed time.

[0025] The simulated urine odor composition may contain various other components, provided that they do not impair the urine odor. Examples of other components include one or more selected from guaiacol, furaneol, phenylethanol, methional, 2-methoxy-5-methylphenol, and 2-methoxy-4-vinylphenol. Among these, phenylethanol and 2-methoxy-4-vinylphenol are preferred.

[0026] A method for evaluating the deodorizing effect of an object against urine odor using the simulated urine odor composition according to the present invention (hereinafter referred to as the "evaluation method") is proposed. The object is not particularly limited, but examples include underwear (underwear fibers), diapers, urine pads, bed pads, bed mattresses, sheets, blankets, toilet seat covers, toilet mats, and toilet deodorizers. The simulated urine odor composition can appropriately simulate the actual urine odor that is generated from urine that has been attached to underwear for a period of time, and is therefore particularly suitable when evaluating the deodorizing effect of underwear fibers as the object.

[0027] When evaluating the deodorizing effect on underwear fibers, the odor bag containing the underwear fibers is filled with nitrogen gas, then a simulated urine odor composition is injected, and the bag is left standing at 40-60°C. The deodorizing effect is then evaluated by comparing the concentrations of the components of the simulated urine odor composition before and after a predetermined time (e.g., 10 minutes to 1 hour) using a gas chromatograph-mass spectrometer. The deodorizing effect is evaluated based on whether the concentration after the predetermined time has decreased compared to the concentration before (start), and if so, the amount of change. [Examples]

[0028] The present invention will be described in detail below with reference to examples. However, the present invention is not limited to the following examples.

[0029] The examples and comparative examples were prepared using the formulations shown in Table 1. Details of each component in Table 1 are as follows: Ammonia water: Ammonia water, manufactured by Kanto Chemical Co., Ltd., 28-30% Phenylacetic acid: Phenylacetic acid, manufactured by Fujifilm Wako Pure Chemical Industries, Ltd., >98% p-cresol: p-cresol, Tokyo Chemical Industry Co., Ltd., >99% Phenylethanol: 2-phenylethyl alcohol, Tokyo Chemical Industry Co., Ltd., >98% Aminoacetophenone: p-aminoacetophenone, manufactured by Fujifilm Wako Pure Chemical Industries, Ltd., 98%

[0030] [Table 1]

[0031] For the examples and comparative examples, eight panelists (research subjects) who passed the olfactory test performed a sensory evaluation to determine whether or not they perceived a urine odor. The olfactory test was conducted in accordance with the examination used to select panels for conducting the olfactory measurement method (a method for determining the presence or absence of odor by smell) as stipulated in Article 12 of the Odor Prevention Law. Table 1 shows the number of people who perceived a urine odor among the eight panelists, four men and four women in their 30s and 40s.

[0032] As can be seen from Table 1, in Examples 1-3, which used phenylacetic acid, more than half of the panelists perceived it as having a urine odor. In particular, in Example 3, which used phenylacetic acid, p-cresol, and aminoacetophenone in a predetermined mass ratio, seven panelists perceived it as having an actual urine odor. Furthermore, in Examples 1-3, all of the panelists who perceived it as having a urine odor felt it was similar to the urine odor that develops when urine is left on underwear for a period of time.

[0033] In contrast, in Comparative Examples 1-3, which did not use phenylacetic acid, the number of people who perceived a urine odor was less than the number of people who did not. In particular, Example 1, which used ammonia alone, which is generally considered to be responsible for the urine odor, had the largest number of people who did not perceive a urine odor. Furthermore, Comparative Example 2, which used p-cresol alone, which is said to contribute significantly to the urine odor in Patent Document 2, and Comparative Example 3, which used p-cresol and phenylethanol, had an odor that was more like a chemical smell than a urine odor.

Claims

1. Containing phenylacetic acid, aminoacetophenone, and p-cresol, A simulated urine odor composition that mimics the smell of human urine.

2. comprising phenylacetic acid and p-cresol, The mass ratio of the p-cresol content to the phenylacetic acid content (p-cresol / phenylacetic acid) is between 1 / 9 and 9 / 1. A simulated urine odor composition that mimics the smell of human urine.

3. The mass ratio of the content of aminoacetophenone to the content of phenylacetic acid (aminoacetophenone / phenylacetic acid) is 1 / 9 to 9 / 1. The simulated urine odor composition according to claim 1.

4. Using any of the simulated urine odor compositions of claims 1 to 3, the odor of the target object is Evaluate the deodorizing effect. Evaluation method.

5. The aforementioned object is a fiber used for underwear. The evaluation method of claim 4.

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