Quantitative-dose spray aerosol product for pest control and pest control method

Abstract

To provide a quantitative injection type aerosol product for insect pest control less in stimulation feeling, hardly contaminating a spray object, capable of diffusion a hardly volatilization insecticidal compound to a wide range uniformly, and exhibiting excellent insect pest controlling effect, and an insect pest controlling method.SOLUTION: There is provided a quantitative injection type aerosol product for insect pest control in which an aerosol composition consisting of a stock solution containing a hardly volatilization insecticidal compound with vapor pressure of less than 1×10-5 mmHg (25°C), and a propellant is filled, the stock solution is contained at 40 vol.% or less in the aerosol composition, and injection amount per 1 time is 0.1 to 1.0 mL.SELECTED DRAWING: None

Description

[Technical Field]

[0001] The present invention relates to a metered-dose aerosol product and a method for controlling pests. More specifically, the present invention relates to a metered-dose aerosol product and a method for controlling pests that cause less irritation, are less likely to contaminate the target object, can uniformly disperse a low-volatility insecticidal compound over a wide area, and exhibit excellent pest control effects. [Background technology]

[0002] Conventionally, insecticides and aerosol products for pest control are known that primarily contain volatile insecticidal compounds such as transfluthrin, and that obtain insecticidal effects by allowing such insecticidal compounds to naturally volatilize (for example, Patent Documents 1-2). In addition, aerosol products and pump products that increase the spray volume to disperse the insecticidal compound over as wide an area as possible are known. Furthermore, aerosol products for pest control that primarily contain non-volatile insecticidal compounds are also known. [Prior art documents] [Patent Documents]

[0003] [Patent Document 1] Japanese Patent Publication No. 2003-73203 [Patent Document 2] Japanese Patent Publication No. 2010-280633 [Overview of the project] [Problems that the invention aims to solve]

[0004] However, in the pest control methods described in Patent Documents 1 and 2, if volatile insecticides such as transfluthrin are used, the volatile insecticides may volatilize and become airborne during spraying, potentially leading to inhalation by the user. In this case, the user may experience irritation. Furthermore, if the spray volume is large (for example, more than 1 mL per spray), the floor, clothing, etc., in the vicinity of the sprayed area may become contaminated (liquid stains, etc.). Moreover, aerosol products containing non-volatile insecticides do not have sufficient diffusion properties, and their use is limited to spraying directly at pests such as cockroaches or spraying in their habitats, and they have not been applied to clothing stored in confined spaces such as closets.

[0005] This invention has been made in view of the above-mentioned conventional problems, and aims to provide a quantitative spray aerosol product and pest control method for pest control that exhibits excellent pest control effects, is less irritating, can uniformly disperse a low-volatility insecticide compound over a wide area, and is less likely to cause localized contamination by uniformly adhering the low-volatility insecticide compound to the target object for spraying. [Means for solving the problem]

[0006] The inventors diligently researched the conditions for solving the above problems and obtained the following findings. Specifically, they found that by spraying an aerosol composition consisting of a predetermined amount of stock solution containing a non-volatile insecticide compound exhibiting a predetermined vapor pressure and a propellant, with the amount of each spray adjusted to a specific amount, it is possible to produce a product that causes less irritation, uniformly diffuses the non-volatile insecticide compound over a wide area, and uniformly adheres the non-volatile insecticide compound to the target object, thereby reducing localized contamination and exhibiting excellent pest control effects, thus completing the present invention. In other words, the present invention's quantitative spray type aerosol product and pest control method for pest control, which solve the above problems, mainly includes the following components.

[0007] (1) Vapor pressure is 1 × 10 -5An aerosol product for pest control, filled with an aerosol composition comprising a stock solution containing a non-volatile insecticidal compound having a vapor pressure of less than mmHg (25°C) and an aerosol, wherein the stock solution is contained so as to be 40% by volume or less in the aerosol composition, and the injection amount per injection is 0.1 to 1.0 mL.

[0008] (2) The non-volatile insecticidal compound-containing aerosol product for pest control according to (1), which contains phenothrin or permethrin.

[0009] (3) The aerosol product for pest control according to (1) or (2), which is used for a narrow space in which clothes are stored.

[0010] (4) A pest control method in which an aerosol composition comprising a stock solution containing a non-volatile insecticidal compound having a vapor pressure of less than 1 × 10 -5 mmHg (25°C) and an aerosol is injected so that the injection amount per injection is 0.1 to 1.0 mL, and the stock solution is contained so as to be 40% by volume or less in the aerosol composition.

Advantages of the Invention

[0011] According to the present invention, it is possible to provide an aerosol product for pest control and a pest control method that have little irritation, can uniformly diffuse a non-volatile insecticidal compound over a wide range, are less likely to cause local contamination by uniformly attaching the non-volatile insecticidal compound to the object to be sprayed, and exhibit an excellent pest control effect.

Brief Description of the Drawings

[0012] [Figure 1] Figure 1 is a schematic diagram of an experimental apparatus for explaining a method for confirming the repellent effect against mites.

Embodiments for Carrying Out the Invention

[0013] <Aerosol Product for Quantitative Injection for Pest Control> One embodiment of the present invention provides a quantitative spray aerosol product for pest control (hereinafter also referred to as the aerosol product) with a vapor pressure of 1 × 10⁻⁶ -5 The aerosol product comprises an aerosol container filled with an aerosol composition consisting of a stock solution containing a non-volatile insecticide compound with a concentration of less than mmHg (at 25°C) and a propellant; a valve mechanism attached to the aerosol container; a stem mechanism attached to the valve mechanism; and a spray button with a nozzle for operating the stem mechanism and valve mechanism and for spraying the aerosol composition. The stock solution is included in the aerosol composition at a concentration of 40% by volume or less. The aerosol product of this embodiment is adjusted so that the amount sprayed per application is 0.1 to 1.0 mL. The respective components will be described below. The aerosol product of this embodiment is characterized in that the type of non-volatile insecticide compound, the content of the stock solution, and the amount sprayed per application of the aerosol composition are adjusted to the above-mentioned specific type and range. Therefore, other components (for example, the shape of the aerosol product, other components and their amounts, various physical properties such as the internal pressure of the container, etc.) are not particularly limited as long as they satisfy the above range. Therefore, all of the following detailed descriptions are illustrative, except that the types of non-volatile insecticidal compounds, the content of the stock solution, and the amount of aerosol composition sprayed per application are adjusted to fall within the specific types and ranges described above.

[0014] (Undiluted) The undiluted solution has a vapor pressure of 1 × 10⁻⁶ -5 Contains non-volatile insecticidal compounds with a vapor pressure of less than mmHg (25°C). The vapor pressure of the non-volatile insecticidal compounds is 1 × 10⁻⁶. -5 It is sufficient if it is less than mmHg (25℃), 5 × 10 -6 It is preferable that the value is 1 × 10 mmHg (at 25°C) or less. -6 It is more preferable that the vapor pressure of the non-volatile insecticide compound be 1 × 10⁻⁶ mmHg (25°C) or less. -5 Because the pH is below mmHg (at 25°C), aerosol products tend to maintain their pest control effect for a long period of time after adhering to the object being sprayed.

[0015] The non-volatile insecticidal compound is not particularly limited as long as it exhibits a pest control effect. Examples of the non-volatile insecticidal compound include insecticidal compounds such as pyrethroid compounds, carbamate compounds, neonicotinoid compounds, chitin synthesis inhibitor compounds, juvenile hormone-like compounds, etc. These non-volatile insecticidal compounds may be used in combination.

[0016] The pyrethroid compound is not particularly limited as long as its vapor pressure is less than 1×10 -5 mmHg (25°C). Examples of the pyrethroid compound include, for example, phenothrin (vapor pressure: 1.43×10 -7 mmHg (21°C)), permethrin (vapor pressure: 5.18×10 -8 mmHg (25°C)), bifenthrin (vapor pressure: 1.34×10 -8 mmHg (25°C)), cyfluthrin (vapor pressure: 1.5×10 -10 mmHg (20°C)), cyphenothrin (vapor pressure: 1.7×10 -9 mmHg (20°C)), silafluofen (vapor pressure: 9.0×10 -7 mmHg (20°C)), etc. Among these, from the viewpoint of high insecticidal effect, the pyrethroid compound preferably contains phenothrin or permethrin. The vapor pressures of phenothrin, cyfluthrin, cyphenothrin, and silafluofen are less than 1×10 -5 mmHg at 25°C.

[0017] The carbamate compound is not particularly limited as long as its vapor pressure is less than 1×10 -5 mmHg (25°C). Examples of the carbamate compound include, for example, carbaryl (vapor pressure: 1.36×10 -6 mmHg (25°C)), etc.

[0018] The neonicotinoid compound is not particularly limited as long as its vapor pressure is less than 1×10 -5 mmHg (25°C). Examples of the neonicotinoid compound include, for example, dinotefuran (vapor pressure: 1.3×10 -8 mmHg (25°C)), imidacloprid (vapor pressure: 3.0×10-12 Examples include mmHg (at 25°C), etc.

[0019] Chitin synthesis inhibitory compounds have a vapor pressure of 1 × 10⁻⁶ -5 The compound is not particularly limited as long as it is less than mmHg (25℃). Examples of chitin synthesis inhibitory compounds include diflubenzuron (vapor pressure: 9.0 × 10⁻⁶). -10 Examples include mmHg (at 25°C), etc.

[0020] The juvenile hormone-like compound has a vapor pressure of 1 × 10⁻⁶ -5 The compound is not particularly limited as long as the mmHg (at 25°C) is less than mmHg. Examples of juvenile hormone-like compounds include pyriproxyfen (vapor pressure: 9.8 × 10⁻⁶). -8 Examples include mmHg (23℃). The vapor pressure of pyriproxyfen is 1 × 10⁻⁶ mmHg (23℃). -5 It is less than mmHg.

[0021] By using these insecticidal compounds as low-volatility insecticidal compounds, various pests such as clothes moths and cloth moths, cockroaches such as German cockroaches, American cockroaches, Japanese cockroaches, and brown cockroaches, spiders, centipedes, ants, house centipedes, millipedes, pill bugs, sowbugs, termites, caterpillars, mites, fleas, bed bugs, lice, booklice, and other crawling pests, as well as flying pests such as mosquitoes, flies, moths, bees, stink bugs, carpet beetles, cigarette beetles, and woodworms can be effectively controlled.

[0022] The content of the insoluble insecticide compound is not particularly limited. The content of the insoluble insecticide compound can be adjusted as appropriate depending on the type of insoluble insecticide compound. For example, the content of the insoluble insecticide compound is preferably 30 w / v% or more, and more preferably 40 w / v% or more, in the undiluted solution. On the other hand, the content of the insoluble insecticide compound may be 100 w / v% in the undiluted solution. If the content of the insoluble insecticide compound is less than 30 w / v%, the aerosol product may not be able to fully exert the desired insecticidal effect or may not spread over a wide area.

[0023] The stock solution may contain, as appropriate, easily volatile insecticide compounds in addition to the above-mentioned non-volatile insecticide compounds. Examples of easily volatile insecticide compounds include pyrethroid compounds and organophosphorus compounds. An example of an easily volatile pyrethroid insecticide is profluthrin (vapor pressure: 7.72 × 10⁻⁶). -5 mmHg (25℃), empenthrin (vapor pressure: 1.05 × 10⁻⁶) -4 Examples include mmHg (23.5℃)). Examples of easily volatile organophosphorus insecticides include dichlorvos (vapor pressure: 1.20 × 10⁻⁶). -2 Examples include mmHg (20℃)).

[0024] Furthermore, when a readily volatile insecticide is included, the amount of readily volatile insecticide is not particularly limited. The amount of readily volatile insecticide can be adjusted as appropriate depending on the type of readily volatile insecticide. For example, the amount of readily volatile insecticide in the undiluted solution is preferably 1 w / v% or more, and more preferably 5 w / v% or more. On the other hand, the amount of readily volatile insecticide in the undiluted solution is preferably 30 w / v% or less, and more preferably 20 w / v% or less. When the amount of readily volatile insecticide is within the above range, the aerosol product has the advantage of being less irritating and easily dispersible over a wide area.

[0025] The stock solution may contain a solvent in addition to the above-mentioned non-volatile insecticidal compound. The solvent may be included to dissolve the above-mentioned non-volatile insecticidal compound as appropriate, making it easier to mix with the propellant in the aerosol container, or to make the stock solution easier to handle during production.

[0026] The solvent is not particularly limited. Examples of solvents include ethanol, isopropyl alcohol (IPA), isopropyl myristate (IPM), liquid paraffin, and kerosene. Among these, ethanol, IPA, and IPM are preferred as solvents because they readily dissolve poorly volatile insecticidal compounds, are inexpensive, and are easy to handle.

[0027] If a solvent is present, the solvent content is not particularly limited. The solvent content is preferably 1% by volume or more, more preferably 5% by volume or more, and even more preferably 10% by volume or more in the stock solution. On the other hand, the solvent content is preferably 99% by volume or less, and more preferably 90% by volume or less in the stock solution. If the solvent content is less than 1% by volume, the aerosol product may not be able to sufficiently dissolve the involatile insecticide compound, depending on the type of involatile insecticide compound. On the other hand, if the solvent content exceeds 99% by volume, the aerosol product may have a low content of the involatile insecticide compound, making it difficult to obtain sufficient pest control effect.

[0028] In addition to the above-mentioned non-volatile insecticidal compound and the solvent as appropriate, the stock solution may contain optional components. Examples of optional components include various fragrances; antibacterial agents; nonionic, anionic, or cationic surfactants; antioxidants such as butylhydroxytoluene; stabilizers such as citric acid and ascorbic acid; inorganic powders such as talc and silicic acid, deodorants, and dyes.

[0029] (propellant) The propellant is the substance that is pressurized and filled into the aerosol container along with the concentrate. The propellant is sprayed together with the concentrate from the nozzle of the spray button, which will be described later, when the valve mechanism, which will be described later, is activated. At that time, the propellant provides the thrust when spraying the concentrate, and also atomizes the aerosol composition into fine particles and diffuses it into the air.

[0030] The type of propellant is not particularly limited. Examples of propellants include liquefied gases and compressed gases. Examples of liquefied gases include liquefied petroleum gas, aliphatic hydrocarbons with 3 to 5 carbon atoms such as propane, n-butane, isobutane, n-pentane, and isopentane, hydrofluoroolefins such as trans-1,3,3,3-tetrafluoropropa-1-ene and trans-2,3,3,3-tetrafluoropropa-1-ene, dimethyl ether, and mixtures thereof. Examples of compressed gases include nitrogen gas, carbon dioxide gas, nitrous oxide gas, and compressed air.

[0031] In this embodiment, the propellant is preferably included in the aerosol composition at an amount of 95% by volume or less, and more preferably at an amount of 80% by volume or less. Furthermore, the propellant is preferably included in the aerosol composition at an amount of 60% by volume or more, and more preferably at an amount of 65% by volume or more.

[0032] In this embodiment, the undiluted solution should be included in the aerosol composition at an amount of 40% by volume or less, and preferably at an amount of 35% by volume or less. Furthermore, it is preferable that the undiluted solution be included in the aerosol composition at an amount of 5% by volume or more, and more preferably at an amount of 10% by volume or more. If the content of the undiluted solution in the aerosol composition is less than 5% by volume, the aerosol composition tends to have a low content of the non-volatile insecticidal compound and does not provide sufficient pest control effect.

[0033] When the aerosol container is filled with the stock solution and propellant, the internal pressure at 25°C is preferably 0.2 MPa or higher, and more preferably 0.25 MPa or higher. Furthermore, the internal pressure at 25°C is preferably 0.8 MPa or lower, and more preferably 0.7 MPa or lower. If the internal pressure of the aerosol container is less than 0.2 MPa, the aerosol composition may drip from the nozzle after spraying, and the diffusion of the non-volatile insecticide compound may be poor. On the other hand, if the internal pressure of the aerosol container exceeds 0.8 MPa, the aerosol composition may leak from the aerosol container.

[0034] Returning to the overall description of aerosol products, the aerosol product, including the concentrate and propellant described above, is pressurized and filled into an aerosol container. The aerosol container is not particularly limited. For example, an aerosol container is a substantially cylindrical pressure-resistant vessel with an opening formed at the top. The opening is a filling port for filling the aerosol composition, and after the concentrate is filled, it is closed by a valve mechanism described later.

[0035] The material of the aerosol container is not particularly limited. Examples of materials for aerosol containers include metals such as aluminum and tinplate, synthetic resins such as polyethylene terephthalate, and pressure-resistant glass.

[0036] The valve mechanism is a mechanism for dispensing the aerosol composition filled in the aerosol container. It is attached to the opening of the aerosol container and closes the opening. The valve mechanism in this embodiment also has a quantitative chamber for temporarily storing the aerosol composition dispensed from the aerosol container. The volume of the quantitative chamber corresponds to the volume of the aerosol composition dispensed in a single spray. The volume of the quantitative chamber in this embodiment is 0.1 to 1.0 mL.

[0037] The stem mechanism is the part attached to the valve mechanism, and it has an internal passage for sending the concentrate and propellant taken into the valve mechanism to the spray button, which will be described later. The internal passage is opened and closed as needed by the stem rubber of the stem mechanism.

[0038] The spray button is a component that sprays the undiluted liquid, which has been drawn in from the aerosol container via a valve mechanism and stem mechanism, together with the propellant. The spray button has a nozzle formed therein for spraying the aerosol composition.

[0039] The number, dimensions, and shape of the nozzles are not particularly limited. The number of nozzles may be, for example, one or two or more. The dimensions (diameter) of the nozzles are preferably 0.4 to 0.7 mm. The shape (cross-sectional shape) of the nozzles may be circular, elliptical, square, or various irregular shapes.

[0040] In this embodiment, when the user operates the spray button, the stem mechanism and valve mechanism are activated, creating communication between the inside and outside of the aerosol container. As a result, a fixed amount of the aerosol composition inside the aerosol container is dispensed according to the pressure difference between the inside and outside of the container and sprayed from the nozzle of the spray button.

[0041] The aerosol composition sprayed by the aerosol product of this embodiment preferably has a spray force of 2.0 gf or more, and more preferably 5.0 gf or more, at a distance of 30 cm from the nozzle at 25°C. Furthermore, the spray force of the aerosol composition preferably has a spray force of 14.0 gf or less, and more preferably 10.0 gf or less, at a distance of 30 cm from the nozzle at 25°C. If the spray force is less than 2.0 gf, the sprayed aerosol composition does not easily diffuse over a wide area. On the other hand, if the spray force exceeds 14.0 gf, when the sprayed aerosol composition is sprayed in an application space, a large amount of the inert insecticide compound tends to adhere to the walls of the space, etc., and less adherence to the object to be sprayed. By adjusting the spray force of the aerosol product of this embodiment to be within the above range, it is easy to uniformly diffuse the inert insecticide compound over a wide area. The spray force of the sprayed aerosol composition can be calculated, for example, by measuring the maximum value when the aerosol composition is sprayed from a distance of 30 cm perpendicular to the surface of a φ60 mm circular flat plate attached to a digital force gauge (DS2-2N, manufactured by IMADA Co., Ltd.), towards the center of the flat plate. In this embodiment, the method for adjusting the spray force is not particularly limited. Such a spray force can be appropriately adjusted depending on the type of aerosol composition, internal pressure, number and shape of the nozzles, etc.

[0042] The aerosol product of this embodiment is adjusted so that the amount sprayed per shot is 0.1 to 1.0 mL. Preferably, the amount sprayed per shot is adjusted to 0.1 to 0.4 mL. If the amount sprayed per shot is less than 0.1 mL, the sprayed aerosol composition may not diffuse uniformly, and sufficient pest control effect may not be obtained. On the other hand, if the amount sprayed per shot exceeds 1.0 mL, the sprayed aerosol composition is likely to contaminate the object being sprayed. The method for adjusting the amount sprayed per shot is not particularly limited. The amount sprayed per shot can be adjusted, for example, by appropriately adjusting the volume of the metering chamber in the valve mechanism, the time during which the inside and outside of the aerosol container communicate when the spray button is operated, etc.

[0043] The aerosol product of this embodiment achieves excellent pest control by spraying an aerosol composition consisting of a predetermined amount of stock solution containing the above-mentioned non-volatile insecticidal compound exhibiting a predetermined vapor pressure and a propellant, with the spray volume adjusted to 0.1 to 1.0 mL per spray, thereby reducing irritation, minimizing contamination of the sprayed object, and enabling the non-volatile insecticidal compound to be uniformly diffused over a wide area. Furthermore, to minimize contamination of the sprayed object, it is more preferable to use a spray volume of 0.4 mL or less per spray.

[0044] The method for manufacturing the aerosol product of this embodiment is not particularly limited. For example, the aerosol product can be manufactured by filling an aerosol container with a stock solution, closing the opening of the aerosol container with a valve mechanism equipped with a metering chamber, pressurizing and filling the propellant via a stem mechanism, and then attaching a spray button. Examples of spray buttons include trigger buttons and push-down buttons.

[0045] The application location of the aerosol product of this embodiment is not particularly limited. The aerosol product of this embodiment can be applied to any desired space where pest control is to be performed. Examples of application locations include clothing storage spaces (clothing cases, drawers, wardrobes, closets, walk-in closets, storage rooms, etc.), gaps between various furniture and home appliances and floors or walls, shoe racks, suitcases, bathrooms, and other semi-enclosed or enclosed spaces. Among these, the aerosol product of this embodiment can be suitably used in narrow spaces for storing clothing, such as closets. When used in such narrow spaces, the aerosol product can uniformly spray the aerosol composition over a wide area, for example, inside the closet. Furthermore, the aerosol product can uniformly adhere the non-volatile compounds in the aerosol composition to clothing. Therefore, the walls of the closet and clothing are prevented from being contaminated by localized high concentrations of non-volatile compounds. In this case, clothing is less likely to develop stains. In this embodiment, a confined space refers to a semi-enclosed or enclosed space with a volume of approximately 50L to 18000L (about 4.5 tatami mats). The aerosol product of this embodiment exhibits excellent diffusion in a confined space, particularly when used in a space with a volume of 50L to 2500L, resulting in minimal liquid staining on the sprayed object. When the volume of the application area is less than 50L, the concentration of the chemical in such a space tends to be high, making liquid staining on the sprayed object more likely. On the other hand, when the volume of the application area exceeds 18000L, convection of airflow due to spraying is less likely to occur, making it difficult to uniformly spray the chemical onto the sprayed object. Furthermore, spraying too much chemical to ensure uniform application tends to make liquid staining more likely.

[0046] Furthermore, while the spraying angle of an aerosol product is not particularly limited as long as it can be sprayed in a way that allows for easy and uniform diffusion over a wide area, it is preferable to spray it diagonally upwards. When spraying diagonally upwards, the spraying angle is preferably 0 to 75 degrees from the horizontal to the diagonal upwards.

[0047] As described above, the aerosol product of this embodiment causes less irritation, is less likely to contaminate the sprayed object, and can uniformly disperse the non-volatile insecticidal compound over a wide area, allowing it to adhere to the sprayed object. For example, with a single spray of this aerosol product of this embodiment, 5 mg / m² can be applied to the sprayed object (e.g., closets, clothing, etc.). 2 The above-mentioned non-volatile insecticidal compounds can be applied to the surface. As a result, excellent pest control effects are achieved over a long period of time.

[0048] <Pest control methods> A pest control method according to one embodiment of the present invention has a vapor pressure of 1 × 10⁻⁶ -5 This method involves spraying an aerosol composition consisting of a stock solution containing a non-volatile insecticidal compound with a concentration of less than mmHg (at 25°C) and a propellant, wherein the stock solution is present in an amount of 40% by volume or less in the aerosol composition, with a spray volume of 0.1 to 1.0 mL per application.

[0049] In carrying out the pest control method of this embodiment, the aerosol composition and aerosol product may be the same as those described in the above embodiment.

[0050] In this embodiment, the number of sprays may be just one. According to the pest control method of this embodiment, the undiluted solution contains a non-volatile compound. Therefore, the user is less likely to feel irritation. In addition, because the non-volatile compound can be sprayed uniformly over a wide area, it is less likely to contaminate the sprayed object (e.g., floors or clothing), and the excellent pest control effect is easily sustained. Although the pest control method of this embodiment can achieve the desired effect with just one spray, the number of sprays may be two or more depending on the size of the space. [Examples]

[0051] The present invention will be described more specifically below with reference to examples. The present invention is not limited in any way to these examples.

[0052] (Example 1) 4.24 g of phenothrin (4 mL) was filled into an aerosol container with a diameter of 35 mm and a height of 68 mm. After attaching a valve (0.2 cc metering valve), 16 mL of propellant (liquefied petroleum gas, specific gravity: 0.55 g / mL) was pressurized and filled so that the mixing ratio (volume ratio) of the concentrate to the propellant was 20:80. A spray button was then attached to create the aerosol product. The internal pressure (25°C) of this aerosol product was 0.49 MPa. Using this aerosol product, 42.4 mg of the concentrate is sprayed per use.

[0053] (Example 2) 3.00 g of permethrin was weighed and diluted to 6 mL using 99.5% ethanol. The resulting mixed solution was used as the stock solution, and an aerosol product was prepared in the same manner as in Example 1, except that 14 mL of propellant (liquefied petroleum gas, specific gravity: 0.56 g / mL) was pressurized and filled into the stock solution to achieve a volume ratio (combination ratio) of 30:70. The internal pressure (at 25°C) of this aerosol product was 0.39 MPa. Using this aerosol product, 30.0 mg of the active ingredient is sprayed per use.

[0054] (Example 3) 3.18 g of phenothrin (3 mL) was filled into an aerosol container similar to that in Example 1, and a valve (0.1 cc metering valve) was attached. Then, 17 mL of propellant (liquefied petroleum gas, specific gravity: 0.56 g / mL) was pressurized and filled so that the mixing ratio (volume ratio) of the stock solution to the propellant was 15:85. A spray button was attached to produce the aerosol product. The internal pressure (25°C) of this aerosol product was 0.39 MPa. Using this aerosol product, 15.9 mg of the stock solution is sprayed per use.

[0055] (Example 4) 3.00 g of phenothrin was weighed and diluted to 6 mL using 99.5% ethanol. The resulting mixed solution was used as the stock solution, and an aerosol product was prepared in the same manner as in Example 1, except that 14 mL of propellant (liquefied petroleum gas, specific gravity: 0.56 g / mL) was pressurized and filled into the stock solution to achieve a volume ratio (combination ratio) of 30:70. The internal pressure (at 25°C) of this aerosol product was 0.39 MPa. Using this aerosol product, 30.0 mg of the active ingredient is sprayed per use.

[0056] (Example 5) 4.24 g of phenothrin (4 mL) was filled into an aerosol container with a diameter of 35 mm and a height of 68 mm. After attaching a valve (1.0 cc metering valve), 16 mL of propellant (liquefied petroleum gas, specific gravity: 0.56 g / mL) was pressurized and filled so that the mixing ratio (volume ratio) of the concentrate to the propellant was 20:80. A spray button was then attached to create the aerosol product. The internal pressure (25°C) of this aerosol product was 0.39 MPa. Using this aerosol product, 212.0 mg of the concentrate is sprayed per use.

[0057] (Comparative Example 1) 1.93 g of phenothrin was weighed and diluted to 4 mL using 99.5% ethanol. The resulting mixture was used as the stock solution and filled into an aerosol container with a diameter of 35 mm and a height of 68 mm. After attaching a valve (2.2 cc metering valve), 16 mL of propellant (liquefied petroleum gas, specific gravity: 0.56 g / mL) was pressurized and filled so that the mixing ratio (volume ratio) of the stock solution to the propellant was 20:80. A spray button was then attached to create the aerosol product. The internal pressure (at 25°C) of this aerosol product was 0.39 MPa. Using this aerosol product, 212.3 mg of the stock solution is sprayed per use.

[0058] (Comparative Example 2) The active ingredient is 5.55 g of transfluthrin (4 mL, vapor pressure: 4.12 × 10⁻⁶). -5An aerosol product was prepared in the same manner as in Example 1, except that 16 mL of mmHg (25°C) and propellant (liquefied petroleum gas, specific gravity: 0.56 g / mL) were used. The internal pressure (25°C) of this aerosol product was 0.39 MPa. Using this aerosol product, 55.5 mg of the active ingredient is sprayed per use.

[0059] (Comparative Example 3) 3.00 g of phenothrin was weighed and diluted to 15 mL using 99.5% ethanol. The resulting mixed solution was used as the stock solution, and an aerosol product was prepared in the same manner as in Example 1, except that 5 mL of propellant (liquefied petroleum gas, specific gravity: 0.56 g / mL) was pressurized and filled into the stock solution with propellant so that the mixing ratio (volume ratio) of stock solution to propellant was 75:25. The internal pressure (25°C) of this aerosol product was 0.39 MPa. Using this aerosol product, 30.0 mg of the active ingredient is sprayed per use.

[0060] The aerosol products obtained in Examples 1-5 and Comparative Examples 1-3 were evaluated for their diffusivity, irritation, staining on clothing, and spraying power using the following methods. The results are shown in Table 1.

[0061] <Diffusibility of aerosol compositions> In stainless steel chest of drawers A (dimensions: width 64cm, depth 60cm, height 130cm, volume: approximately 500L), four pieces of wool cloth (10cm x 10cm) were suspended at positions 27cm from the front, 11cm from the left and right sides, and 15cm or 95cm from the top. Each aerosol product was sprayed once horizontally. 24 hours after spraying, the amount of the agent adhering to the cloth was analyzed by gas chromatography, and the average of the analytical values ​​for the four pieces of cloth was calculated. The diffusivity was then evaluated according to the following evaluation criteria. See Table 1 for aerosol spraying conditions. In Example 4, the diffusivity was also evaluated for stainless steel chest of drawers B (dimensions: width 85cm, depth 133cm, height 191cm, volume: approximately 2159L). In this case, the aerosol composition was sprayed four times, and each spray was performed from a consistent position. (Evaluation Criteria) ○: The average amount of chemical adhering to four pieces of cloth is 5 mg / m². 2 That was all. ×: The average amount of chemical adhering to 4 pieces of cloth is 5 mg / m². 2 It was less than [amount missing].

[0062] <Evaluation of sensation> A piece of cotton cloth (compliant with JIS L 0803, 5cm x 5cm) was suspended in the center of a stainless steel chest of drawers A (dimensions: width 64cm, depth 60cm, height 130cm, volume: approximately 500L). The aerosol products of Examples 1-5 and Comparative Examples 1-3 were sprayed once from a distance of 20cm from the cloth, and the irritation felt when the cloth sprayed with the aerosol was brought into contact with the skin was evaluated according to the following evaluation criteria. (Evaluation Criteria) ○: I didn't feel any stimulation. ×: I felt stimulated.

[0063] <Liquid stains on clothing> A piece of silk cloth (compliant with JIS L 0803, 6 momme weight, 5cm x 5cm piece) was suspended in the center of a stainless steel chest of drawers A (dimensions: width 64cm, depth 60cm, height 130cm, volume: approximately 500L). The aerosol products of Examples 1-5 and Comparative Examples 1-3 were sprayed once from a distance of 20cm from the cloth, and the degree of liquid staining (contamination) of the cloth was evaluated according to the following evaluation criteria. (Evaluation Criteria) ○: No liquid stains (contamination) occurred. △: Almost no liquid stains (contamination) occurred. ×: Liquid stains (contamination) occurred.

[0064] <Injection power> The maximum value was measured when an aerosol composition was sprayed from a distance of 30 cm perpendicular to the surface of a φ60 mm circular flat plate attached to a digital force gauge (DS2-2N, manufactured by IMADA Co., Ltd.). The measurement was performed three times at 25°C, and the average value was taken as the spray force (gf).

[0065] [Table 1]

[0066] As shown in Table 1, the aerosol products of Examples 1 to 5 all exhibited excellent diffusion properties. Therefore, excellent pest control effects can be expected. These aerosol products can, for example, inhibit the hatching of clothes moth eggs on clothing stored in storage spaces such as chests of drawers. Furthermore, these aerosol products were non-irritating and left almost no liquid stains on the sprayed object (fabric inside a stainless steel chest of drawers). In addition, the aerosol product of Example 4 also exhibited excellent diffusion properties in a diffusion test using stainless steel chest of drawers B (volume: approximately 2159L). Therefore, excellent pest control effects can be expected.

[0067] On the other hand, the aerosol product of Comparative Example 1, which had a spray volume exceeding 1.0 mL per spray, caused liquid stains on the fabric when sprayed into a confined space such as a stainless steel chest of drawers. It was confirmed that the aerosol product of Comparative Example 1 did not cause liquid stains on the fabric when sprayed into a larger space rather than a confined space. Furthermore, the vapor pressure was 1 × 10⁻⁶. -5 Comparative Example 2, an aerosol product containing transfluthrin at a concentration exceeding mmHg (25°C), caused irritation. Furthermore, Comparative Example 3, an aerosol product containing more than 40% by volume of the undiluted solution, exhibited poor diffusion and caused liquid stains on the cloth being sprayed.

[0068] <Lethal effect against clothing pests and nuisance insects> Using the aerosol product described in Example 4 above, the lethal effect against clothing pests and nuisance insects (clothes moth eggs, clothes moth larvae, clothes moth adults, booklice, bark beetles, and cigarette beetles) was confirmed by the following test method.

[0069] (Test method) Under conditions of 25°C and 70% humidity, the test insects were placed in a plastic cup (8cm in diameter, 4cm in height, approximately 200mL in volume) or a glass petri dish and placed in the center of the bottom of a stainless steel chest of drawers A (dimensions: 64cm wide, 60cm deep, 130cm high, volume: approximately 500L). The aerosol product of Example 4 was sprayed once from a position 65cm high, at the center of the width (32cm from the left and right) (sprayed horizontally for clothes moths (eggs, larvae, and adults), and at a 45° angle downwards from the horizontal for other test insects). Two hours after treatment, the lethal number of clothes moths (eggs, larvae, and adults) was counted, and after one night had passed since treatment, the lethal number of booklice, bark beetles, and cigarette beetles was counted, and the mortality rate (%) for each was calculated. The test was conducted twice and compared with an untreated group where no aerosol product was used. The results are shown in Table 2.

[0070] (Test insect) Spiny eggs: approximately 20 Burr larva (about 30 days old): about 10 heads Approximately 20 adult clothes moths Booklice: Approximately 20 individuals Bark beetles: Approximately 10 individuals Cigarette beetles: approximately 10 individuals

[0071] [Table 2]

[0072] As shown in Table 2, the aerosol product of the present invention showed a high mortality rate against all clothing pests and nuisance insects. This demonstrates that the aerosol product of the present invention exhibits excellent pest control effects.

[0073] (Example 6) 1.2 g phenothrin and 0.3 g profluthrin were weighed out as the active ingredients and diluted to 3 mL using 99.5% ethanol. The resulting mixed solution was used as the stock solution. The stock solution was filled into an aerosol container with a diameter of 35 mm and a height of 68 mm. After attaching a valve (0.2 cc metering valve), 17 mL of propellant (liquefied petroleum gas, specific gravity: 0.55 g / mL) was pressurized and filled so that the mixing ratio (volume ratio) of the stock solution to the propellant was 15:85. A spray button (0.6 mm nozzle) was attached to create the aerosol product. The internal pressure (25°C) of this aerosol product was 0.49 MPa. Using this aerosol product, 12 mg of phenothrin and 3 mg of profluthrin are sprayed per use.

[0074] Using the aerosol product of Example 6, tests were conducted to confirm the repellent effect against mites and the lethal effect against clothing pests and nuisance insects using the following methods.

[0075] <Repellent effect against mites> Figure 1 is a schematic diagram of the experimental apparatus used to explain the method for confirming the repellent effect against mites. As shown in Figure 1, in a 15 cm diameter petri dish 1, a 9 cm square piece of black paper 2, four 3.5 cm square pieces of cotton cloth (two vertically and two horizontally, cotton cloths 3a-3d) were placed in order from the bottom of petri dish 1, a 2 cm square piece of black paper 4 was placed in the center of each piece of cotton cloth 3, and bait (fresh culture medium 5) was placed on each piece of black paper 4. Of the cotton cloths 3a-3d, cotton cloths 3a and 3c were sprayed with the contents of the aerosol product of Example 6 using the following method. As a result, the four pieces of cotton cloth 3a-3d were arranged alternately, with some treated with the aerosol product of Example 6 and others not. In addition, approximately 500-1000 test insects (house dust mites) were placed almost evenly in four locations on the outside of the black paper 2. The samples were left to stand overnight at 25°C and 75% RH. The number of test insects that crawled onto the treated (cotton cloth 3a and cotton cloth 3c) and untreated (cotton cloth 3b and cotton cloth 3d) samples was counted, and the repellency rate against mites (%) was calculated using the following formula. The test was performed three times. The obtained repellency rates against mites and the average repellency rate (%) are shown in Table 3. Repellency rate against mites (%) = (Number of crawling mites in the untreated area - Number of crawling mites in the treated area) / (Number of crawling mites in the untreated area) × 100

[0076] (Method for disposing of contents into cotton cloth) The aerosol product prepared in Example 6 was sprayed once horizontally onto cotton cloths 3a and 3c, which were placed in the center of the bottom of a space (dimensions: width 85 cm, depth 133 cm, height 191 cm, volume: approximately 2159 L), from a position 70 cm high and at the center of the width direction (42.5 cm from the left and right). After 2 hours, the cotton cloths were used in the above test.

[0077] [Table 3]

[0078] As shown in Table 3, the aerosol product of the present invention was confirmed to exhibit excellent repellent effects against mites.

[0079] <Lethal effect against clothing pests and nuisance insects> Using the aerosol product of Example 6 described above, the lethal effect against clothing pests and nuisance insects (clothes moth larvae, adult clothes moths, carpet beetles, booklice, bark beetles, and cigarette beetles) was confirmed by the following test method.

[0080] (Test method) Under conditions of 25°C and 70% humidity, test insects were placed in a plastic cup (8cm in diameter, 4cm in height, approximately 200mL in volume) or a glass petri dish and placed in the center of the bottom of a stainless steel chest of drawers A (dimensions: 64cm wide, 60cm deep, 130cm high, volume: approximately 500L). The aerosol product of Example 6 was sprayed once from a position 100cm high, at a 45° angle upward from the horizontal, at the center of the width (32cm from the left and right). The number of lethal clothing pests and nuisance insects was counted 2 hours and 1 day after treatment, and the mortality rate (%) was calculated. The test was performed twice and compared with an untreated group where the aerosol product was not used. The results are shown in Table 4. In Table 4, the numbers without parentheses indicate the results after 2 hours, and the numbers in parentheses indicate the results after 1 day.

[0081] (Test insect) Burr larva (about 30 days old): about 10 heads Approximately 10 adult clothes moths Carpet beetle larvae: approximately 10 individuals Booklice: Approximately 20 individuals Bark beetles: Approximately 10 individuals Cigarette beetles: approximately 10 individuals

[0082] [Table 4]

[0083] As shown in Table 4, the aerosol product of the present invention showed a high mortality rate against all clothing pests and nuisance insects at least one day later. This demonstrates that the aerosol product of the present invention exhibits excellent pest control effects. [Explanation of symbols]

[0084] 1 Petri dish 2 Black paper 3a~3d cotton cloth 4 Black paper 5. Fresh culture medium P1-P4 Test locations for the test insects

Claims

1. Vapor pressure is 1 x 10 -5 The aerosol composition is filled with a stock solution containing a non-volatile insecticide compound with a concentration of less than mmHg (at 25°C) and a readily volatile insecticide compound, and a propellant. The aforementioned non-volatile insecticidal compound includes phenothrin or permethrin. The content of the aforementioned easily volatile insecticide compound is 5 w / v% or more in the undiluted solution. The undiluted solution is included in the aerosol composition in an amount of 40% by volume or less. The mixing ratio (volume ratio) of the stock solution and the propellant is 5:95 to 15:

85. A metered-dose aerosol product for pest control, with a spray volume of 0.1 to 1.0 mL per application.

2. A quantitative spray aerosol product for pest control according to claim 1, for use in confined spaces where clothing is stored.

3. Vapor pressure is 1 x 10 -5 A method for controlling pests, comprising an aerosol composition comprising a stock solution containing a non-volatile insecticide compound with a concentration of less than mmHg (at 25°C) and a readily volatile insecticide compound, and a propellant, wherein the non-volatile insecticide compound contains phenothrin or permethrin, the content of the readily volatile insecticide compound is 5 w / v% or more in the stock solution, the stock solution is included in the aerosol composition in an amount of 40% by volume or less, and the mixing ratio (volume ratio) of the stock solution to the propellant is 5:95 to 15:85, and the aerosol composition is sprayed in a manner that the amount of sprayed per application is 0.1 to 1.0 mL.

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