Disinfectant composition

Abstract

To provide a disinfectant composition with superior efficacy in disinfecting general bacteria, fungi, and bacteria resistant to cationic surfactants.SOLUTION: A disinfectant composition comprises component (A): a quaternary ammonium salt type cationic surfactant, component (B): a biguanide compound, component (C): at least one selected from a nonionic surfactant and an ampholytic surfactant, and component (D): water. The mass ratio of component (A) to component (B), (A) / (B), is 10 or more and 200 or less.SELECTED DRAWING: None

Description

[Technical Field]

[0001] The present invention relates to a disinfectant composition and a disinfection method. Specifically, the present invention relates to a disinfectant composition used for hygiene management of equipment and instruments in food factories, kitchens, medical facilities, etc., and more specifically, to a disinfectant composition having excellent disinfecting properties against bacteria and fungi in organic stains. [Background technology]

[0002] Disinfectants are used to reduce the risk of food poisoning and to maintain good hygiene in food factories, kitchens, medical facilities, and other similar facilities. For disinfection in food factories, kitchens, and medical facilities, disinfectants with quaternary ammonium salts as the main component are commonly used. Furthermore, to prevent the proliferation of microorganisms from dirt adhering to and remaining on the disinfected surface, disinfectant compositions combining nonionic surfactants, anionic surfactants, and amphoteric surfactants are used to provide cleaning properties.

[0003] However, disinfectant compositions primarily composed of quaternary ammonium salts have a problem in that they do not exhibit sufficient disinfecting power when the surface to be disinfected contains a large amount of organic contaminants such as lipids, polysaccharides such as starch, proteins, and pigments, or when organic contaminants are introduced during cleaning. In addition, quaternary ammonium salts can sometimes lead to the emergence of cationic surfactant-resistant bacteria, and residual bacteria can contaminate food and utensils, causing food spoilage and deterioration of the sanitary environment.

[0004] Regarding conventional disinfectant cleaning agents, Patent Document 1 describes a disinfectant composition comprising a cationic surfactant and 1,2-benzisothiazole-3-one. Reference Document 2 describes a disinfectant composition containing a dialkyldimethylammonium salt and a biguanide compound as essential components, and at least one nonionic surfactant selected from the group consisting of polyoxyethylene alkyl ether, polyoxyethylene polyoxypropylene block copolymer, and alkyldimethylamine oxide. Reference Document 3 describes a cleaning and disinfecting agent composition containing one or more compounds selected from the group consisting of polyhexamethylene biguanide hydrochloride, polyhexamethylene guanidine phosphate, polyhexamethylene guanidine hydrochloride, and polyaminopropyl biguanide hydrochloride, a cationic surfactant comprising one or more dilong-chain alkyl dishort-chain alkylammonium methyl sulfates, and a nonionic surfactant comprising a polyoxyalkylene alkyl ether with a specific HLB combination. [Prior art documents] [Patent Documents]

[0005] [Patent Document 1] Japanese Patent Publication No. 2020-050617 [Patent Document 2] Japanese Patent Application Publication No. 2-184609 [Patent Document 3] Japanese Patent Publication No. 2020-033414 [Overview of the Initiative] [Problems that the invention aims to solve]

[0006] However, while the disinfectant cleaning agent compositions described in Patent Documents 1 to 3 exhibit disinfecting properties against bacteria and mold, they did not show sufficient disinfecting properties when organic stains were present.

[0007] Therefore, the object of the present invention is to provide a disinfectant composition that has excellent disinfecting power even when dirt is present on the surface to be disinfected. [Means for solving the problem]

[0008] In order to solve the above problems, the present inventors conducted diligent studies and found that a disinfectant composition containing (A) a quaternary ammonium salt type cationic surfactant, (B) a biguanide compound, (C) at least one selected from nonionic surfactants and amphoteric surfactants, and (D) water, with a mass ratio of (A) to (B) of 10 or more and 200 or less, can solve the problems that existed in conventional disinfectants, and thus completed the present invention.

[0009] In other words, the present invention is (1) As component (A), a quaternary ammonium salt type cationic surfactant, (B) Component is a biguanide compound, (C) Component is at least one selected from nonionic surfactants and amphoteric surfactants, (D) Water as component A disinfectant composition containing (A) and having a mass ratio (A) / (B) of 10 or more and 200 or less, (2) The disinfectant composition of (1), wherein component (A) contains at least one selected from dialkyldimethylammonium chloride, dialkyldimethylammonium methosulfate, and dialkylmethylpolyoxyethylammonium propionate. (3) The disinfectant composition of (1), wherein component (B) contains polyhexamethylene biguanide hydrochloride. (4) The (C) component contains a nonionic surfactant which is an alcohol alkoxylate having a branched alkyl group with 8 or more carbon atoms and 18 or fewer carbon atoms, as in (1) Exclusion Fungal agent composition, (5) The component (C) is an alcohol alkoxylate obtained by adding alkylene oxide to a secondary alcohol having 8 or more carbon atoms and 18 or fewer carbon atoms, as in (4) Exclusion Fungal agent composition, (6) The disinfectant composition of (1) further contains an isothiazolin compound as component (E), (7) The disinfectant composition according to (1), wherein the pH of the disinfectant composition at 25°C is 6 or more and 8 or less. (8) A disinfection method comprising bringing the disinfectant composition according to any one of (1) to (7) into contact with a disinfected object having organic dirt. (9) A disinfection method comprising a step of immersing a disinfected object having organic dirt in a disinfectant solution containing the disinfectant composition according to any one of (1) to (7), and a step of removing the disinfectant solution from the disinfected object after immersion, and (10) A disinfection method comprising a step of spraying the disinfectant composition according to any one of (1) to (7) or a disinfectant solution containing the disinfectant composition onto a disinfected object having organic dirt, then allowing the disinfected object to stand or scrubbing it, and a step of rinsing with water. [Advantages of the Invention]

[0010] The disinfectant composition of the present invention has a disinfection effect on general bacteria, fungi, and cationic surfactant-resistant bacteria even when organic dirt is present on the disinfected object. [Modes for Carrying Out the Invention]

[0011] The present invention is a disinfectant composition containing the above components (A) to (D) as essential components, and the value of the mass ratio (A) / (B) of component (A) to component (B) is 10 or more and 200 or less. The disinfectant composition of the present invention contains a quaternary ammonium salt type cationic surfactant as component (A). This component (A) mainly contributes to the disinfection effect.

[0012] As the component (A), any quaternary ammonium salt type cationic surfactant having a bactericidal effect can be used. For example, dialkyldimethylammonium salts, alkyldimethylbenzylammonium salts, alkyltrimethylammonium salts, alkyldimethylhydroxyethylammonium salts, alkyldimethylethylammonium salts, alkyldimethylethylbenzylammonium salts, dialkylethylmethylammonium salts, dialkylmonomethylhydroxyammonium salts, alkyldipolyoxyethylmethylammonium salts, dialkylmethylpolyoxyethylammonium salts, benzethonium salts and the like can be mentioned.

[0013] Among these, a quaternary ammonium salt compound (i) having four alkyl groups, one or two of which are linear or branched alkyl groups having 8 to 16 carbon atoms and the rest are alkyl groups having 1 or 2 carbon atoms, or a quaternary ammonium compound salt (ii) having two or three alkyl groups, the rest being polyoxyalkylene groups, at least one alkyl group being a linear or branched alkyl group having 8 to 1 | 6 carbon atoms and the remaining alkyl groups being alkyl groups having 1 or 2 carbon atoms is preferred. A part of the hydrogen atoms of the alkyl group may be substituted with a hydroxyl group.

[0014] Examples of quaternary ammonium salt compounds (i) include dialkyldimethylammonium salt, alkyltrimethylammonium salt, alkyldimethylhydroxyethylammonium salt, alkyldimethylethylammonium salt, and dialkylethylmethylammonium salt. Examples of quaternary ammonium salt compounds (ii) include alkyldipolyoxyethylmethylammonium salt and dialkylmethylpolyoxyethylammonium salt. Examples of dialkyldimethylammonium salts include octyldecyldimethylammonium chloride, dioctyldimethylammonium chloride, and didecyldimethylammonium methosulfate, and specifically, Lipocard (trademark) 210-80E manufactured by Lion Specialty Chemicals Co., Ltd. is commercially available. Examples of alkyltrimethylammonium salts include behentrimonium chloride, and specifically, Lipocard (trademark) 22-80 manufactured by Lion Specialty Chemicals Co., Ltd. is commercially available. Specifically, Prepargen (trademark) HY manufactured by Clariant Japan Co., Ltd. is commercially available as an alkyldimethylhydroxyethylammonium salt. Specifically, dialkylmethylpolyoxyethylammonium salts such as Bardap® 26, manufactured by Arcsada Japan Co., Ltd., are commercially available.

[0015] As "linear or branched alkyl groups having 8 to 16 carbon atoms," linear alkyl groups having 8 to 16 carbon atoms are preferred, linear alkyl groups having 8 to 14 carbon atoms are more preferred, and linear alkyl groups having 8 to 12 carbon atoms are even more preferred.

[0016] More specifically, component (A) is preferably a dialkyldimethylammonium salt or a dialkylmethylpolyoxyethylammonium salt, more preferably a linear alkyl group having 8 to 14 carbon atoms, and even more preferably a linear alkyl group having 8 to 12 carbon atoms.

[0017] Examples of suitable salts include chlorine, bromine, alkyl sulfate esters having 1 or 2 carbon atoms, and fatty acids having 1 to 12 carbon atoms. However, chlorine, propionic acid, and alkyl sulfate esters having 1 or 2 carbon atoms are preferred in terms of disinfectant properties.

[0018] The disinfectant composition of the present invention contains a biguanide compound as component (B). This component (B) primarily contributes to the disinfectant effect. (B) Any biguanide compound that exhibits antibacterial activity can be used as component (B). Examples include polyhexamethylene biguanide hydrochloride, polyaminopropyl biguanide hydrochloride, and chlorhexidine gluconate, with polyhexamethylene biguanide hydrochloride being preferred.

[0019] The disinfectant composition of the present invention contains at least one selected from nonionic surfactants and amphoteric surfactants as component (C). Component (C) is thought to contribute to disinfection in the presence of organic contaminants.

[0020] (C) When component is a nonionic surfactant, examples include polyoxyethylene alkyl ethers, polyoxyethylene alkenyl ethers, polyoxyethylene polyoxypropylene alkyl ethers (the addition of ethylene oxide and propylene oxide may be random or blocky), polyethylene glycol propylene oxide adducts, polypropylene glycol ethylene oxide adducts, glycerin fatty acid esters or their ethylene oxide adducts, sorbitan fatty acid esters, polyoxyethylene sorbitan fatty acid esters, alkyl polyglucosides, fatty acid monoethanolamides or their ethylene oxide adducts, fatty acid-N-methyl monoethanolamides or their ethylene oxide adducts, fatty acid diethanolamides (e.g., coconut oil fatty acid diethanolamide) or their ethylene oxide adducts, sucrose fatty acid esters, alkyl (poly)glycerin ethers, polyglycerin fatty acid esters, polyethylene glycol fatty acid esters, fatty acid methyl ester ethoxylates, and the like. Among these, polyalkylene oxide adducts such as coconut oil fatty acid diethanolamide polyoxyethylene alkyl ether, polyoxyethylene alkenyl ether, and polyoxyethylene polyoxypropylene alkyl ether are preferred due to their good antibacterial properties against bacteria and fungi in organic stains, and nonionic surfactants represented by the following general formula (1) are more preferred:

[0021] R 1 -(OC2H4) n -(OC3H6) m -OH (1) (In the formula, R 1 (where n represents an aliphatic hydrocarbon group with 8 to 18 carbon atoms, n represents a number between 1 and 20, and m represents a number between 0 and 12.)

[0022] R in general formula (1) 1This represents an aliphatic hydrocarbon group having 8 to 18 carbon atoms, preferably a linear or branched alkyl group or alkenyl group. Examples of such groups include alkyl groups such as linear or branched octyl group, linear or branched nonyl group, linear or branched decyl group, linear or branched dodecyl group, linear or branched tridecyl group, linear or branched isotridecyl group, linear or branched tetradecyl group, linear or branched pentadecyl group, linear or branched hexadecyl group, linear or branched peptadecyl group, and linear or branched octadecyl group; and alkenyl groups such as linear or branched decenyl group, linear or branched pentadecenyl group, and linear or branched octadecenyl group. Among these, linear or branched alkyl groups with 8 or more carbon atoms and 18 carbon atoms are preferred, and linear or branched alkyl groups with 10 or more carbon atoms and 14 carbon atoms are more preferred, due to their superior ability to disinfect bacteria and fungi in organic stains.

[0023] In general formula (1), n ​​is a number between 1 and 20, preferably between 3 and 18, and more preferably between 5 and 15. m is a number between 0 and 12, preferably between 1 and 10, and more preferably between 3 and 9. Furthermore, the average value of n is preferably 2 or more and 19 or less, more preferably 3 or more and 18 or less, and even more preferably 5 or more and 15 or less. The average value of m is preferably 0 or more and 11 or less, more preferably 1 or more and 10 or less, and even more preferably 3 or more and 9 or less.

[0024] Furthermore, component (C) is R of general formula (1). 1 The alcohol alkoxylate may be a branched alkyl group having 8 or more carbon atoms and 18 or fewer carbon atoms, preferably 10 or more carbon atoms and 16 or fewer carbon atoms, and more preferably 12 or more carbon atoms and 14 or fewer carbon atoms. Since the alcohol alkoxylate is obtained by adding either or both of ethylene oxide and propylene oxide to a secondary alcohol, the R of general formula (1) 1The residue may be a secondary alcohol having 8 to 18 carbon atoms, preferably 10 to 16 carbon atoms, and more preferably 12 to 14 carbon atoms, from which a hydroxyl group has been removed. In this case, n is preferably 3 to 18, m is preferably 3 to 9, the average value of n is preferably 3 to 18, and the average value of m is preferably 3 to 9.

[0025] When component (C) is an amphoteric surfactant, examples include alkylaminoacetic acid betaine, alkylamidopropyl betaine, sulfobetaine, alkylamino(mono or di)propionate salt, imidazolinium betaine, alkylamine oxide, alkylaminoethylglycine, alkyldi(aminoethyl)glycine, glycine n-(3-aminopropyl)C10-16 derivatives, alkylpolyaminoethylglycine, alkylβ-alanine, alkyldiethanolamine, polyoxyalkylenealkylamine, and oxyethylene-added surfactants of diamines. Among these, alkyldimethylamine oxide is preferred, alkyldimethylamine oxide having an alkyl group with 8 to 18 carbon atoms is more preferred, alkyldimethylamine oxide having an alkyl group with 10 to 16 carbon atoms is even more preferred, and alkyldimethylamine oxide having an alkyl group with 10 to 14 carbon atoms is even more preferred.

[0026] The above components (A) to (C) may each be a single component or a combination of multiple components.

[0027] The disinfectant composition of the present invention contains water as component (D). As the water, tap water, softened water, purified water, RO water, ion-exchanged water, and distilled water can be used. As an example of tap water, tap water from Arakawa Ward, Tokyo (pH=7.6, total alkalinity (calcium carbonate equivalent) 40.5 mg / L, German hardness 2.3°DH (of which calcium hardness 1.7°DH, magnesium hardness 0.6°DH), chloride ions 21.9 mg / L, sodium and its compounds 15 mg / L, nitrate nitrogen and nitrite nitrogen 1.2 mg / L, fluorine and its compounds 0.1 mg / L, boron and its compounds 0.04 mg / L, total trihalomethanes 0.016 mg / L, residual chlorine 0.4 mg / L, organic matter (total organic carbon content) 0.7 mg / L) can be used. The water in (D) of this invention is the remainder of the total amount of components (A) to (C) above, or the remainder of the total amount of components (A) to (C) and other arbitrary components.

[0028] The concentration of component (A) in the disinfectant composition is not particularly limited as long as it achieves the effects of the present invention, but from the viewpoint of economic efficiency, distributionability and storage stability of the disinfectant composition as a product, it is preferably 10% by mass or more and 50% by mass or less, more preferably 15% by mass or more and 40% by mass or less, and even more preferably 20% by mass or more and 38% by mass or less, based on the total amount of the disinfectant composition.

[0029] The concentration of component (B) in the disinfectant composition is not particularly limited as long as it achieves the effects of the present invention, but from the viewpoint of the economic efficiency of the disinfectant composition as a product and storage stability, it is preferably 0.05% by mass or more and 5% by mass or less, more preferably 0.1% by mass or more and 2% by mass or less, and even more preferably 0.2% by mass or more and 0.8% by mass or less, based on the total amount of the disinfectant composition.

[0030] The concentration of component (C) in the disinfectant composition is not particularly limited as long as it achieves the effects of the present invention, but from the viewpoint of the economic efficiency and storage stability of the disinfectant composition as a product, it is preferably 0.5% by mass or more and 20% by mass or less, more preferably 1% by mass or more and 10% by mass or less, and even more preferably 1.5% by mass or more and 10% by mass or less, based on the total amount of the disinfectant composition.

[0031] The mass ratio of component (A) to component (B) of the disinfectant composition of the present invention must be such that the value of (A) / (B) is 10 or more and 200 or less, preferably 20 or more and 180 or less, more preferably 30 or more and 180 or less, even more preferably 50 or more and 150 or less, and most preferably 80 or more and 150 or less. If the value of (A) / (B) is less than 10, the rinsability and stability of the disinfectant composition may be insufficient, and if it is greater than 200, the disinfecting effect may be poor.

[0032] The disinfectant composition of the present invention may contain an isothiazolin compound as component (E) in addition to the above components (A) to (D). Component (E) exhibits excellent antibacterial activity against cationic-resistant bacteria. Examples of isothiazolin compounds include 2-methyl-4-isothiazolin-3-one, 2-n-octyl-4-isothiazolin-3-one, 5-chloro-2-methyl-4-isothiazolin-3-one, 4-chloro-2-n-octyl-4-isothiazolin-3-one, 4,5-dichloro-2-n-octyl-4-isothiazolin-3-one, and 1,2-benzisothiazolin-3-one. Among these, 2-methyl-4-isothiazolin-3-one and 1,2-benzisothiazolin-3-one are preferred.

[0033] The concentration of component (E) in the disinfectant composition is not particularly limited as long as it achieves the effects of the present invention, but from the viewpoint of economic efficiency and marketability of the disinfectant composition as a product, it is preferably 0.01% by mass or more and 10% by mass or less, more preferably 0.05% by mass or more and 3% by mass or less, and even more preferably 0.1% by mass or more and 2% by mass or less, based on the total amount of the disinfectant composition.

[0034] The disinfectant composition of the present invention may further contain, as needed, pH adjusters, glycol-based solvents and / or glycol ether-based solvents, chelating agents, dyes, other disinfectants, defoaming agents, fragrances, corrosion inhibitors, natural extracts, thickeners, enzymes, and the like.

[0035] Examples of pH adjusters include lithium hydroxide, potassium hydroxide, sodium hydroxide, cerium hydroxide, calcium hydroxide, magnesium hydroxide, barium hydroxide, aluminum hydroxide, sodium carbonate, sodium metasilicate, sodium acetate, potassium phosphate, sodium phosphate, sodium hydrogen phosphate, N,N-dimethylethanolamine, N,N-dibutylethanolamine, N-(β-aminoethyl)ethanolamine, N-methylethanolamine, N-methyldiethanolamine, N-ethylethanolamine, N-ethyldiethanolamine, and Nn-butyldiethanolamine. Examples include alkalis such as Nt-butylethanolamine, Nt-butyldiethanolamine, N-(β-aminoethyl)isopropanolamine, N,N-diethylisopropanolamine, 2-amino-2-hydroxymethyl-1,3-propanediol, aminomethylpropanol, tetrahydroxypropylethylenediamine, morpholine, N-methylmorpholine, N-ethylmorpholine, piperazine, hydroxyethylpiperazine, 2-methylpiperazine, trans-2,5-dimethylpiperazine, and cis-2,6-dimethylpiperazine, as well as acids such as acetic acid, hydrochloric acid, sulfuric acid, nitric acid, and phosphoric acid.

[0036] Examples of the glycol-based solvents include ethylene glycol, diethylene glycol, triethylene glycol, propylene glycol, dipropylene glycol, tripropylene glycol, isoprene glycol, 1,2-butylene glycol, and 1,3-butylene glycol.

[0037] Examples of glycol ether solvents include ethylene glycol monomethyl ether, ethylene glycol monoethyl ether, ethylene glycol monopropyl ether, ethylene glycol monobutyl ether, ethylene glycol monohexyl ether, ethylene glycol monophenyl ether, diethylene glycol monomethyl ether, diethylene glycol monoethyl ether, diethylene glycol monopropyl ether, diethylene glycol monobutyl ether, diethylene glycol monobenzyl ether, triethylene glycol monomethyl ether, triethylene glycol monoethyl ether, triethylene glycol monopropyl ether, triethylene glycol monobutyl ether, triethylene glycol monohexyl ether, triethylene glycol monophenyl ether, propylene glycol monomethyl ether, propylene glycol monoethyl ether, propylene glycol monopropyl ether, propylene glycol monobutyl ether, dipropylene glycol monomethyl ether, dipropylene glycol monoethyl ether, dipropylene glycol monopropyl ether, dipropylene glycol monobutyl ether, ethylene glycol dimethyl ether, diethylene glycol dimethyl ether, diethylene glycol methyl ethyl ether, propylene glycol methyl ethyl ether, and dipropylene glycol methyl ethyl ether. These may be used individually or in combination of two or more.

[0038] Examples of chelating agents include ethylenediaminetetraacetic acid, nitrilotriacetic acid, methylglycinediacetic acid, hydroxyethylenediaminetriacetic acid, diethylenetriaminopentaacetic acid, triethylenetetraaminehexaacetic acid, hydroxyethyliminodiacetic acid, dihydroxyethylglycine, glutamic acid diacetic acid, aspartic acid diacetic acid, β-alanine diacetic acid, serine diacetic acid, tripolyphosphate, and alkali metal salts thereof.

[0039] Examples of pigments include natural pigments, synthetic pigments, or mixtures thereof. Examples of other disinfectants include sodium hypochlorite, potassium hypochlorite, sodium chlorite, potassium chlorite, sodium chlorate, potassium chlorate, sodium perchlorate, potassium perchlorate, sodium chlorinated isocyanurate, potassium chlorinated isocyanurate, ε-polylysine, poly-γ-glutamic acid, nisin, etc. Examples of defoaming agents include silicone-based defoaming agents, polyether-based defoaming agents, higher alcohol-based defoaming agents, etc. Examples of fragrances include natural fragrances, synthetic fragrances, or blends thereof. Examples of corrosion inhibitors include polycarboxylic acids such as short-chain dicarboxylic acids or tricarboxylic acids, phosphate esters, triazoles such as benzotriazole, tolyltriazole or mercaptobenzothiazole, phosphonic acids such as 1-hydroxyethylidene-1,1-diphosphonic acid, adipic acid, glutaric acid, or succinic acid, etc. Examples of natural extracts include those derived from plants such as hemp, Rubiaceae, Brassicaceae, Poaceae, Ebenaceae, Asteraceae, Lamiaceae, Zingiberaceae, Camellia, Solanaceae, Cupressaceae, Myrtaceae, Vitaceae, Fabaceae, Rutaceae, and Liliaceae, as well as natural extracts derived from animals such as lysozyme and leek protein extract. Examples of thickeners include carrageenan, xanthan gum, guar gum, locust bean gum, gatcha gum, karaya gum, and pectin. Examples of enzymes include lipase, alkaline amylase, amylase, cellulase, protease, and pullulanase.

[0040] The pH of the disinfectant composition of the present invention is preferably 4 or higher and 11.5 or lower, and more preferably 6 or higher and 8 or lower, from the viewpoint of preventing metal corrosion.

[0041] In a disinfection method using the disinfectant composition of the present invention, the disinfectant composition can be used as is as a disinfectant solution, or a disinfectant solution can be prepared by diluting it with water or hot water at a ratio of 2 to 1000 times. The water or hot water used here can be tap water, softened water, purified water, RO water, ion-exchanged water, or distilled water, which are the same as component (D) of the liquid disinfectant cleaning agent composition of the present invention.

[0042] The amount of component (A) in the disinfectant solution obtained by diluting the disinfectant composition of the present invention is usually preferably 0.01% by mass or more and 10% by mass or less, more preferably 0.02% by mass or more and 1% by mass or less, and particularly preferably 0.05% by mass or more and 0.5% by mass or less, based on the total mass of the disinfectant solution. The amount of component (B) in the disinfectant solution obtained by diluting the disinfectant composition of the present invention is usually preferably 0.00005% by mass or more and 1% by mass or less, more preferably 0.0001% by mass or more and 0.1% by mass or less, and particularly preferably 0.0003% by mass or more and 0.03% by mass or less, based on the total mass of the disinfectant solution.

[0043] The amount of component (C) in the disinfectant solution obtained by diluting the disinfectant composition of the present invention is usually preferably 0.0005% by mass or more and 4% by mass or less, more preferably 0.001% by mass or more and 0.4% by mass or less, and particularly preferably 0.003% by mass or more and 0.03% by mass or less, based on the total mass of the disinfectant solution. The amount of component (E) in the disinfectant solution obtained by diluting the liquid disinfectant cleaning agent composition of the present invention is usually preferably 0.00001% by mass or more and 2% by mass or less, more preferably 0.00002% by mass or more and 0.2% by mass or less, and particularly preferably 0.0003% by mass or more and 0.06% by mass or less, based on the total mass of the disinfectant solution.

[0044] The disinfectant composition of the present invention is used by directly contacting equipment such as conveyor belts in food factories, kitchens, medical facilities, and other equipment and instruments used in such facilities. When performing the disinfection method using the disinfectant composition of the present invention, the temperature of the disinfectant composition or the disinfectant solution containing the disinfectant composition is adjusted to 0°C to 90°C. The disinfection method of the present invention can employ methods such as spraying the disinfectant solution onto the object to be disinfected using a foaming cleaning machine (spray gun) or immersing the object to be disinfected in the disinfectant solution. After spraying or immersion, it is preferable to remove the disinfectant composition by rinsing with water. The spraying time or immersion time can be appropriately selected depending on the type and amount of microorganisms, the type and amount of organic or inorganic contaminants, the concentration of the disinfectant solution, etc. The disinfectant composition of the present invention is particularly effective against objects to be disinfected that have organic contaminants present. [Examples]

[0045] The present invention will be specifically described below with reference to examples and comparative examples. The components used in the formulations of the examples and comparative examples are shown below. In the following examples, etc., "%" represents mass percent unless otherwise specified, and the numerical values ​​of the formulations in the examples and comparative examples in the table represent the mass percent of the pure content. The compounds used in the examples and comparative examples are listed below. Regarding the notation of alkyl groups, for example, when it is written as alkyl(C8~18), it represents a mixture having alkyl groups with 8 or more carbon atoms and 18 or less.

[0046] (A) component A-1: Octyldecyldimethylammonium chloride A-2: Dioctyldimethylammonium chloride A-3: Didecylmethylpoly(oxyethyl)ammonium propionate A-4: Didecyldimethylammonium methosulfate A-5: Bis-Alkanoyl (3-aminopropyl)dimethylammonium chloride A-6: Alkyldimethylhydroxyethylammonium chloride (Clariant) (Manufactured by Japan Co., Ltd., product name "Prepagen (trademark) HY") A-7: Alkyl (C8-18) dimethylbenzylammonium chloride

[0047] (B) Component B-1: Polyhexamethylene biguanide hydrochloride B-2: Polyaminopropyl biguanide hydrochloride B-3: Chlorhexidine gluconate

[0048] (C) Component C-1: Polyoxyethylene alkyl (C9-11) ether (manufactured by Aoki Oil & Fat Industry Co., Ltd., product name "Safety Cut (trademark) LI-3062") C-2: Polyoxyalkylene alkyl ether (manufactured by ADEKA, product name "ADEKA (trademark) BO-901") C-3: Alkylene oxide adduct 1 of secondary alcohol (C12-C14) (manufactured by Nippon Shokubai Co., Ltd., product name "Softanol (trademark) EP12030", block polymerization of ethylene oxide with an average addition mole count of 12 and propylene oxide with an average addition mole count of 3) C-4: Alkylene oxide adduct 2 of secondary alcohols (C12-C14) (manufactured by Nippon Shokubai Co., Ltd., product name "Softanol (trademark) EP7085", block polymerized with an average of 7 moles of ethylene oxide added and an average of 8.5 moles of propylene oxide added) C-5: Dodecyldimethylamine oxide (manufactured by Clariant Japan, product name "Genaminox (trademark) K-12") C-6: Coconut oil fatty acid diethanolamide (manufactured by ADEKA Corporation, product name "ADEKASOLE") (Mark) COA”) C-7: Alkylene oxide adduct of lauryl alcohol (manufactured by Miyoshi Oil & Fat Co., Ltd., product name "Pelletex (trademark) PC-2465") C-8: Lauryldimethylaminoacetate betaine (manufactured by Kao Corporation, product name "Anchitol (trademark) 24B")

[0049] (D) Component D-1: Tap water

[0050] (E) Component E-1:1,2-Benzisothiazoline-3-one E-2: 2-methyl-4-isothiazolin-3-one E-3:2-n-octyl-4-isothiazoline-3-one

[0051] (F) Other ingredients F-1: Ethylene glycol F-2: Propylene glycol F-3: Ethylenediaminetetraacetate sodium salt F-3: Hydrochloric acid F-4: Sodium hydroxide

[0052] The compositions of each example were prepared by adding water (component D) to a mixing tank so that the total composition amounted to 100% by mass, then adding components (A), (B), and (C) (and (E) and (F) as needed) to the mixing tank, and thoroughly mixing and stirring.

[0053] Examples 1-40, Comparative Examples 1-6 The disinfectant compositions shown in Tables 1 to 5 were prepared. The disinfecting properties, metal corrosion prevention properties, rinseability, and storage stability of each disinfectant composition were measured. Tables 1 to 4 show the results for Examples 1 to 40, and Table 5 shows the results for Comparative Examples 1 to 6. Examples 1-20 in Tables 1 and 2, and Examples 21-25, 29, and 30 in Table 3 are for reference only.

[0054] *1: pH measurement method A pH measuring composite electrode (HORIBA; glass ground-joint sleeve type) was connected to a pH meter (HORIBA; pH / ion meter F-23), and the power was turned on. A saturated potassium chloride aqueous solution (3.33 mol / L) was used as the internal solution for the pH electrode. Next, 100 mL beakers were filled with pH 4.01 standard solution (phthalate standard solution), pH 6.86 (neutral phosphate standard solution), and pH 9.18 standard solution (borate standard solution), and the beakers were immersed in a 25°C constant temperature bath for 30 minutes. The pH measuring electrode was immersed in the standard solutions adjusted to constant temperature for 3 minutes, and calibration was performed in the order of pH 6.86 → pH 9.18 → pH 4.01. Each disinfectant composition was filled into a 100 mL beaker and adjusted to 25°C in a constant temperature bath. A pH measuring electrode was immersed in the temperature-adjusted sample for 3 minutes to measure the pH of the composition.

[0055] *2: Disinfection test (General bacteria: No stains) The bacterial strain used was Escherichia coli (NBRC3972).

[0056] 2-1: Culturing of bacterial strains Escherichia coli was streaked onto SCD agar (Nissui Pharmaceutical Co., Ltd.), incubated at 37°C for 24 hours, then the colonies were scraped off and diluted in sterile phosphate-buffered saline to be used as bacterial suspensions.

[0057] 2-2: Preparation of Sterilization Neutralizing Solution 10 g of soy lecithin, 30 g of Tween80, 1 g of L-histidine, and 20 g of sodium thiosulfate were dissolved in 1 L of distilled water while being heated, and then cooled while stirring. Afterward, 9 mL of each solution was dispensed into screw-cap test tubes, and sterilized by autoclaving (121°C, 20 minutes) to obtain sterile neutralized solutions.

[0058] 2-3: Disinfection test (General bacteria: No stains) Test method: Each disinfectant composition was diluted to 0.25% by mass with deionized water to prepare a disinfectant cleaning solution. 10 mL of this solution was then mixed with a final concentration of 1.5-5.0 × 10⁶. 8 0.1 mL of each bacterial suspension was added to achieve the desired CFU / mL ratio, and the mixture was allowed to come into contact with the suspension at 25°C for 5 minutes to prepare the test solution. 1 mL of each test solution was added to a sterile neutralizing solution and thoroughly mixed. The mixture was then mixed and solidified on SCD agar medium and incubated at 37°C for 2 days. After incubation, the number of viable bacteria was measured, and the bactericidal effect was evaluated based on the difference from the initial bacterial count according to the following criteria. Products rated △, ○, and ◎ were judged to be practical.

[0059] Evaluation criteria: ◎: Log reduction of the test bacteria is 4 or higher. ○: Log reduction of the test bacteria is 2 or greater, but less than 4. △: Log reduction of the test bacteria is 1 or greater, but less than 2. ×: Log reduction of the test bacterium is less than 1.

[0060] *3: Disinfection test (general bacteria: dirt present) As the test strain, Escherichia coli (NBRC3972) was used.

[0061] 3-1: Cultivation of the strain Escherichia coli was smeared on SCD agar medium (Nissui Pharmaceutical Co., Ltd.), cultured at 37°C for 24 hours, and the colonies were scraped off. The colonies were diluted in sterile phosphate-buffered saline containing 2% by mass of yeast extract (manufactured by Shioya MS Co., Ltd., product name "Powder Yeast Extract D-3H") and 2% by mass of soybean oil (Fuji Film Wako Pure Chemical Industries, Ltd., first grade) as contaminants to obtain a bacterial suspension.

[0062] 3-2: Preparation of the sterilization neutralizing solution 10 g of soy lecithin, 30 g of Tween 80, 1 g of L-histidine, and 20 g of sodium thiosulfate were dissolved by heating in 1 L of distilled water and cooled while stirring. Then, 9 mL of each was dispensed into test tubes with screw caps and sterilized by high pressure (121°C, 20 minutes) to obtain a sterilization neutralizing solution. <00003​​​​​​​​​​​​​​​​​​​​​

[0065] *4: Disinfection test (Cationic surfactant-resistant bacteria: no stains) As the test strain, we used Seratia marcescens (isolated in the field), which exhibits resistance to cationic surfactants.

[0066] 4-1: Culturing of bacterial strains Serratia marcescens was spread onto agar plates containing a cationic surfactant, incubated at 30°C for 24 hours, then the colonies were scraped off and diluted in sterile phosphate-buffered saline to obtain bacterial suspensions.

[0067] 4-2: Preparation of Sterilization Neutralizing Solution 10 g of soy lecithin, 30 g of Tween80, 1 g of L-histidine, and 20 g of sodium thiosulfate were dissolved in 1 L of distilled water while being heated, and then cooled while stirring. Afterward, 9 mL of each solution was dispensed into screw-cap test tubes, and sterilized by autoclaving (121°C, 20 minutes) to obtain sterile neutralized solutions.

[0068] 4-3: Disinfection test (Cationic surfactant-resistant bacteria: no stains) Test method: Each disinfectant composition was diluted to 0.25% by mass with deionized water to prepare a disinfectant cleaning solution. 10 mL of this solution was then mixed with a final concentration of 1.5-5.0 × 10⁶. 8 0.1 mL of each bacterial suspension was added to achieve the desired CFU / mL ratio, and the mixture was allowed to stand at 25°C for 24 hours to prepare the test solution. 1 mL of each test solution was added to a sterile neutralizing solution and thoroughly mixed. The mixture was then mixed and solidified on SCD agar medium (Nissui Pharmaceutical Co., Ltd.) and incubated at 30°C for 2 days. After incubation, the number of viable bacteria was measured, and the bactericidal effect was evaluated based on the difference from the initial bacterial count according to the following criteria. Products with a rating of △, ○, or ◎ were judged to be practical.

[0069] Evaluation criteria: ◎: Log reduction of the test bacteria is 4 or higher. ○: Log reduction of the test bacteria is 2 or greater, but less than 4. △: Log reduction of the test bacteria is 1 or greater, but less than 2. ×: Log reduction of the test bacterium is less than 1.

[0070] *5: Disinfection test (Cationic surfactant-resistant bacteria: dirt present) As the test strain, we used Seratia marcescens (isolated in the field), which exhibits resistance to cationic surfactants.

[0071] 5-1: Culturing of bacterial strains Serratia marcescens was spread onto an agar medium containing a cationic surfactant, incubated at 30°C for 24 hours, and then the colonies were scraped off. Each colony was treated as a contaminant and diluted in sterile phosphate-buffered saline containing 2% by mass of yeast extract (manufactured by Shioya MS Co., Ltd., product name "Powdered Yeast Extract D-3H") and 2% by mass of soybean oil (Fujifilm Wako Pure Chemical Industries, Grade 1) to create a bacterial suspension.

[0072] 5-2: Preparation of Sterilization Neutralizing Solution 10 g of soy lecithin, 30 g of Tween80, 1 g of L-histidine, and 20 g of sodium thiosulfate were dissolved in 1 L of distilled water while being heated, and then cooled while stirring. Afterward, 9 mL of each solution was dispensed into screw-cap test tubes, and sterilized by autoclaving (121°C, 20 minutes) to obtain sterile neutralized solutions.

[0073] 5-3: Disinfection test (Cationic surfactant-resistant bacteria: with dirt present) Test method: Each disinfectant composition was diluted to 0.25% by mass with deionized water to prepare a disinfectant cleaning solution. 10 mL of this solution was then mixed with a final concentration of 1.5-5.0 × 10⁶. 8 0.1 mL of each bacterial suspension was added to achieve the desired CFU / mL ratio, and the mixture was allowed to stand at 25°C for 24 hours to prepare the test solution. 1 mL of each test solution was added to a sterile neutralizing solution and thoroughly mixed. The mixture was then mixed and solidified on SCD agar medium (Nissui Pharmaceutical Co., Ltd.) and incubated at 30°C for 2 days. After incubation, the number of viable bacteria was measured, and the bactericidal effect was evaluated based on the difference from the initial bacterial count according to the following criteria. Products with a rating of △, ○, or ◎ were judged to be practical.

[0074] Evaluation criteria: ◎: Log reduction of the test bacteria is 4 or higher. ○: Log reduction of the test bacteria is 2 or greater, but less than 4. △: Log reduction of the test bacteria is 1 or greater, but less than 2. ×: Log reduction of the test bacterium is less than 1.

[0075] *6: Disinfection test (mold spores: no stains) Aspergillus niger (IFO9455) was used as the test strain.

[0076] 6-1: Preparation of spore suspension (Aspergillus niger) The test mold was streaked onto PDA agar (Nissui Pharmaceutical Co., Ltd.) and cultured at 25°C. After culturing, microscopic observation confirmed that sufficient spores had formed. 10 mL of sterile 0.05% Tween20-added physiological saline was placed on the agar plate, and the colonies were scraped off to collect the suspension. The collected suspension was rinsed by removing unwanted hyphae through sterile gauze, and then centrifuged three times at 10,000 rpm at 4°C for 15 minutes. After centrifugation, an appropriate amount of sterile 0.05% Tween20-added physiological saline was added, and the sample was divided into 2.0-9.0 × 10⁶ units. 8 The bacterial count was adjusted to approximately CFU / mL, and a spore suspension was prepared.

[0077] 6-2: Preparation of Sterilization Neutralizing Solution 10 g of soy lecithin, 30 g of Tween80, 1 g of L-histidine, and 20 g of sodium thiosulfate were dissolved in 1 L of distilled water while being heated, and then cooled while stirring. Afterward, 9 mL of each solution was dispensed into screw-cap test tubes, and sterilized by autoclaving (121°C, 20 minutes) to obtain sterile neutralized solutions.

[0078] 6-3: Disinfection test (Mold spores: No stains) Test method: Each disinfectant composition was diluted to 0.25% by mass with deionized water to prepare a disinfectant cleaning solution. 10 mL of this solution was then mixed with a final concentration of 1.5-5.0 × 10⁶. 50.1 mL of spore suspension was added to achieve a concentration of (CFU / mL), and the disinfectant washing solution and spore suspension were brought into contact at 25°C for 30 minutes to prepare the test solution. 1 mL of this test solution was added to the sterile neutralizing solution and thoroughly mixed. The mixture was mixed and solidified on PDA agar medium and incubated at 37°C for 4 days. After incubation, the number of viable bacteria was measured, and the disinfection effectiveness was evaluated based on the difference from the initial bacterial count according to the following criteria. Solutions with a rating of △, ○, or ◎ were judged to be practical.

[0079] Evaluation criteria: ◎: Log reduction of the test bacteria is 3 or higher. ○: Log reduction of the test bacterium is 2 or greater, but less than 3. △: Log reduction of the test bacterium is 1 or greater, but less than 2. ×: Log reduction of the test bacterium is less than 1.

[0080] *7: Disinfection test (mold spores: dirt present) Aspergillus niger (IFO9455) was used as the test strain.

[0081] 7-1: Preparation of spore suspension (Aspergillus niger) The test mold was streaked onto PDA agar medium (Nissui Pharmaceutical Co., Ltd.) and cultured at 25°C. After culturing, microscopic observation confirmed that sufficient spores had formed. 10 mL of sterile 0.05% Tween20-added physiological saline was placed on the agar plate, and the colonies were scraped off to collect the suspension. After removing unwanted hyphae from the collected suspension by passing it through sterile gauze, it was centrifuged three times at 10000 rpm at 4°C for 15 minutes. After centrifugation, an appropriate amount of physiological saline containing sterile 0.05% Tween20, 2% by mass of yeast extract (Shioya MS Co., Ltd., product name "Powdered Yeast Extract D-3H") and 2% by mass of soybean oil (Fujifilm Wako Pure Chemical Industries, Grade 1) was added, and the mixture was divided into 2.0-9.0 × 10⁶. 8 The bacterial count was adjusted to approximately CFU / mL, and a spore suspension was prepared.

[0082] 7-2: Preparation of sterile neutralizing solution 10 g of soy lecithin, 30 g of Tween80, 1 g of L-histidine, and 20 g of sodium thiosulfate were dissolved in 1 L of distilled water while being heated, and then cooled while stirring. Afterward, 9 mL of each solution was dispensed into screw-cap test tubes, and sterilized by autoclaving (121°C, 20 minutes) to obtain sterile neutralized solutions.

[0083] 7-3: Disinfection test (Mold spores: Dirt present) Test method: Each disinfectant composition was diluted to 0.25% by mass with deionized water to prepare a disinfectant cleaning solution. 10 mL of this solution was then mixed with a final concentration of 1.5-5.0 × 10⁶. 5 0.1 mL of spore suspension was added to achieve a concentration of (CFU / mL), and the disinfectant washing solution and spore suspension were brought into contact at 25°C for 30 minutes to prepare the test solution. 1 mL of this test solution was added to the sterile neutralizing solution and thoroughly mixed. The mixture was mixed and solidified on PDA agar medium and incubated at 37°C for 4 days. After incubation, the number of viable bacteria was measured, and the disinfection effectiveness was evaluated based on the difference from the initial bacterial count according to the following criteria. Solutions with a rating of △, ○, or ◎ were judged to be practical.

[0084] Evaluation criteria: ◎: Log reduction of the test bacteria is 3 or higher. ○: Log reduction of the test bacterium is 2 or greater, but less than 3. △: Log reduction of the test bacterium is 1 or greater, but less than 2. ×: Log reduction of the test bacterium is less than 1.

[0085] *8: Cleaning test Test method: A stainless steel plate (SUS304, 75mm long x 25mm wide x 1mm thick) was coated with oil (10g beef tallow, 10g soybean oil, 0.25g monooleic acid glyceride, and 0.1g Sudan III dissolved in 60ml of chloroform) on one side, dried at 25°C for 1-2 hours, and its weight was measured. This test piece was then immersed in 100mL of an aqueous solution prepared by diluting each disinfectant composition to 3% by weight in hard water equivalent to 75mg / L calcium carbonate [German hardness 4.2°DH], left at 25°C for 5 minutes, rinsed with deionized water, air-dried, and its weight measured. The difference in mass between the test piece before cleaning and the stainless steel plate before oil application was defined as the amount of dirt adhering to it. The cleaning rate was calculated from the change in mass of the test piece before and after cleaning using the following formula (1), and the cleaning performance was evaluated according to the following evaluation criteria.

[0086] Cleaning rate (%) = {(Mass of specimen before cleaning - Mass of specimen after cleaning) / (Amount of dirt attached)} × 100 ... (1) Evaluation criteria: ◎: Cleaning rate of 80% or more ○: Cleaning rate 60% or more, less than 80% △: Cleaning rate 40% or more, less than 60% ×: Cleaning rate less than 40% Based on this, △, ○, and ◎ were judged as practical.

[0087] *9: Metal corrosion resistance test (aluminum) Test method: The test specimens [aluminum (A5052P), 50mm long x 30mm wide x 2mm thick] were pre-washed with a neutral detergent, treated with acetone, and dried. Each disinfectant composition was diluted to 0.25% by mass with hard water (calcium carbonate equivalent to 75 mg / L [German hardness 4.2°DH]). 60 mL of this cleaning solution was placed in a 70 mL glass bottle with a lid, and the test specimens were immersed in it and stored in a 25°C incubator for 30 minutes. Afterward, the test specimens were removed, rinsed with deionized water, dried, and the surface condition was visually observed to determine corrosiveness according to the following criteria.

[0088] Evaluation criteria: ○: No corrosion △: Some corrosion is visible, but there are no problems with its use. ×: Corroded Based on this, △ and ○ were judged to be practical.

[0089] *10: Rinsing test Test method: A cleaning solution prepared by diluting each disinfectant composition to 3% by mass at 20°C with hard water equivalent to 75 mg / L of calcium carbonate [German hardness 4.2°DH] was foamed into a foam with a specific gravity of 0.15 g / cubic centimeter using a DEMA 910N PORTABLE FOAMER and sprayed onto the bottom (500 mm long, 700 mm wide) of a stainless steel box [stainless steel (SUS304)] for 20 seconds. After one minute, rinsing (with a shower nozzle) was performed with hard water equivalent to 75 mg / L of calcium carbonate [German hardness 4.2°DH], and the rinsing time until the foam disappeared from around the drain (50 mm in diameter, with a 40-mesh polyethylene net inside) in the center of the bottom of the stainless steel box was judged according to the following criteria.

[0090] Evaluation criteria: 〇: Less than 240 seconds △: 240 seconds or more, less than 480 seconds ×: 480 seconds or more Based on this, △ and ○ were judged to be practical.

[0091] *11: Storage stability test Test method: 100g of each disinfectant composition was placed in a polypropylene container and left to stand for one month at -5°C, 25°C, and 40°C before its appearance was observed.

[0092] Evaluation criteria: ○: No separation or turbidity observed; stable. △: There is no overall separation, and slight turbidity is visible, but there are no problems with use. ×: Separation or turbidity is observed. Based on this, △ and ○ were judged to be practical.

[0093] [Table 1]

[0094] Table 2

[0095] Table 3

[0096] Table 4

[0097] Table 5

Claims

1. A disinfectant composition, (A) As component, a quaternary ammonium salt type cationic surfactant is added in an amount of 20% by mass or more and 50% by mass or less of the total amount of the disinfectant composition. (B) As component, at least one biguanide compound selected from the group consisting of polyhexamethylene biguanide hydrochloride, polyaminopropyl biguanide hydrochloride, and chlorhexidine gluconate is added in an amount of 0.05% by mass or more and 5% by mass or less relative to the total amount of the disinfectant composition. (C) As component, at least one selected from nonionic surfactants and amphoteric surfactants is included in an amount of 0.5% by mass or more and 20% by mass or less relative to the total amount of the disinfectant composition. (D) Component: water, (E) The disinfectant composition contains, as component (E), at least one isothiazolin compound selected from the group consisting of 2-methyl-4-isothiazolin-3-one, 2-n-octyl-4-isothiazolin-3-one, 5-chloro-2-methyl-4-isothiazolin-3-one, 4-chloro-2-n-octyl-4-isothiazolin-3-one, 4,5-dichloro-2-n-octyl-4-isothiazolin-3-one, and 1,2-benzisothiazolin-3-one, in an amount of 0.01% by mass or more and 3% by mass or less based on the total amount of the disinfectant composition. The nonionic surfactant is a fatty acid diethanolamide or an alcohol alkoxylate represented by the following general formula (1). The aforementioned amphoteric surfactant is alkylaminoacetic acid betaine or alkylamine oxide. A disinfectant composition in which the mass ratio (A) / (B) of component (A) to component (B) is 50 or more and 200 or less. R 1 -(OC 2 H 4 ) n -(OC 3 H 6 ) m -OH (1) (In the formula, R1 represents an aliphatic hydrocarbon group having 8 to 18 carbon atoms, n represents a number between 1 and 20, and m represents a number between 0 and 12.)

2. The disinfectant composition according to claim 1, wherein component (A) contains at least one selected from dialkyldimethylammonium chloride, dialkyldimethylammonium methosulfate, and dialkylmethylpolyoxyethylammonium propionate.

3. The disinfectant composition according to claim 1, wherein component (B) contains polyhexamethylene biguanide hydrochloride.

4. The disinfectant composition according to claim 1, wherein component (C) contains the nonionic surfactant and R 1 of the general formula (1) is a branched alkyl group.

5. The disinfectant composition according to claim 4, wherein component (C) is an alcohol alkoxylate obtained by adding an alkylene oxide to a secondary alcohol having 8 or more carbon atoms and 18 or fewer carbon atoms.

6. The disinfectant composition according to claim 1, wherein the pH of the disinfectant composition at 25°C is 6 or higher and 8 or lower. composition.

7. The disinfectant composition according to any one of claims 1 to 6 is used with a body to be disinfected that has organic dirt on it. Disinfection methods that involve contact.

8. A disinfectant solution comprising the steps of immersing an object to be disinfected, which has organic contaminants, in a disinfectant solution containing the disinfectant composition according to any one of claims 1 to 6, and removing the disinfectant solution from the object to be disinfected after immersion. Sterilization method.

9. A disinfectant composition according to any one of claims 1 to 6, or a disinfectant solution containing the disinfectant composition. After spraying the object to be disinfected that has organic contaminants present, either leave the object to stand or scrub it clean. A disinfection method that includes the steps of rinsing and rinsing with water.

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