Skin emulsion composition

Abstract

To provide an emulsion composition for skin that can significantly reduce raw material odors from the coenzyme Q10 and has excellent formulation stability.SOLUTION: An emulsion composition for skin contains the following component A, the following component B, and the following component C, with the content of the component A being more than 0.3 mass% to 1 mass% or less. The component A: coenzyme Q10, component B: naturally occurring vegetable oil and fat, and component C: polyglycerol fatty acid ester-based nonionic surfactant.SELECTED DRAWING: None

Description

[Technical Field]

[0001] The present invention relates to an emulsified composition for skin. [Background Art]

[0002] One of the functions required for skin care preparations is "moisturization". Conventionally, for example, components that constitute intercorneocyte lipids such as ceramides, sphingolipids, and lecithin; components present in corneocytes such as natural moisturizing factor (NMF); components inherently present in the dermis such as hyaluronic acid and collagen; and components that exert various moisturizing effects such as polyhydric alcohols, oil agents, saccharides, and plant extracts are blended in preparations.

[0003] Among such components, coenzyme Q10 has continuously attracted attention as a component having remarkably excellent moisturizing ability. However, while coenzyme Q10 can exert remarkably excellent moisturizing ability, when it is blended in a high amount in expectation of a moisturizing effect, there is a problem that the raw material odor becomes prominent and impedes formulation. Therefore, a method of masking the odor using a fragrance or the like can be considered, but imparting fragrance to a preparation cannot be said to be the best improvement method because it also depends on the user's odor preference. Therefore, development of a method for suppressing odor other than masking methods is demanded.

[0004] Attempts have hitherto been made to suppress odor change over time in preparations containing coenzyme Q10 (see, for example, Patent Document 1). However, this attempt aims at suppressing deterioration and odor change over time in oily skin compositions, and has not led to a fundamental solution for suppressing the raw material odor of coenzyme Q10. Furthermore, from the viewpoint of preparation stability, the technology described in Patent Document 1 cannot be applied to emulsion-type preparations. [Prior Art Literature] [Patent Literature]

[0005] [Patent Document 1] Japanese Unexamined Patent Application Publication No. 2007-084505 [Overview of the project] [Problems that the invention aims to solve]

[0006] The present invention has been made in view of the above-mentioned prior art, and aims to provide a skin emulsifying composition that can significantly reduce the raw material odor of coenzyme Q10 and has excellent formulation stability. [Means for solving the problem]

[0007] In other words, the present invention provides a skin emulsifying composition characterized by containing the following component A, the following component B, and the following component C, wherein the content of component A is more than 0.3% by mass and 1% by mass or less. Ingredient A: Coenzyme Q10 Ingredient B: Naturally derived vegetable oil Ingredient C: Polyglycerin fatty acid ester type nonionic surfactant

[0008] It is preferable that component B is at least one selected from the group consisting of meadowfoam oil, corn oil, rice germ oil, jojoba seed oil, and olive fruit oil.

[0009] The content of component B is preferably 0.01% by mass or more and 15% by mass or less.

[0010] It is preferable that component C is a polyglycerol unsaturated fatty acid ester.

[0011] The above-mentioned emulsified composition for skin use preferably further contains the following component D. Component D: At least one selected from the group consisting of hydrolyzed hyaluronic acid, hyaluronic acid salts, and hyaluronic acid derivatives. [Effects of the Invention]

[0012] The skin emulsifying composition of the present invention, by satisfying the above constituent requirements, exhibits an odor suppression effect in a novel manner, significantly reducing the raw material odor of coenzyme Q10. Furthermore, the skin emulsifying composition of the present invention also exhibits excellent formulation stability. [Modes for carrying out the invention]

[0013] The skin emulsifying composition of the present invention is characterized by containing the following component A, component B, and component C. Ingredient A: Coenzyme Q10 Ingredient B: Naturally derived vegetable oil Ingredient C: Polyglycerin fatty acid ester type nonionic surfactant

[0014] The details of each component used in the skin emulsifying composition of the present invention are described below.

[0015] [Component A] The above-mentioned component A is coenzyme Q10. Coenzyme Q10 is a compound also known as coenzyme Q10, CoQ10, ubiquinone, or ubicarenone. In this invention, by using component A, it is possible to provide the skin with significantly superior moisture, or so-called moisturizing effect, after application.

[0016] Furthermore, component A is not particularly limited, whether it is a single raw material or a mixed raw material with other components. In the present invention, component A can be a commercially available product. Examples of commercially available coenzyme Q10 include Solfonte Q10, Phytopresome Q10, Phytopresome Lipo-Q, and Presome Q10 (trade names, all manufactured by Nippon Seika Co., Ltd.).

[0017] The content of component A in the skin emulsifying composition of the present invention is greater than 0.3% by mass and less than or equal to 1% by mass. From the viewpoint of usability, it is more preferable that it be 0.9% by mass or less. In the present invention, even if component A is included in a high concentration, specifically more than 0.3% by mass, the raw material odor can be significantly reduced by combining it with the components described later. Furthermore, since component A can be included in a high concentration in the present invention, it goes without saying that it provides an exceptionally superior moisturizing effect. Note that the above content of component A is the amount converted to pure content.

[0018] [Component B] The above component B is a naturally derived vegetable oil. Surprisingly, in this invention, the use of component B exhibits a remarkably significant effect that was previously completely unknown: the reduction of the raw material odor of component A. Therefore, even if the content of component A in the skin emulsification composition is greater than 0.3% by mass, it is possible to reduce the raw material odor. In this specification, "naturally derived vegetable oil" refers to oils and fats extracted and refined from lipids contained in plants that exist in nature.

[0019] Examples of the component B used above include almond oil, Astrocaryum murumuru seed butter, African mango kernel fat, avocado oil, Camelina sativa seed oil, linseed oil, Argania spinosa kernel oil, apricot kernel oil, olive fruit oil, cacao butter, Rosa canina fruit oil, canola oil, apricot kernel oil, kukui nut oil, blackcurrant seed oil, corn oil, sesame oil, wheat germ oil, rice bran oil, rice germ oil, pomegranate seed oil, safflower oil, shea butter, Sclerocarya birrea seed oil, soybean oil, tea fruit oil, tea seed oil, evening primrose oil, Camellia japonica seed oil, camellia oil, Theobroma grandiflorum seed butter, maize oil, maize germ oil, persic oil, palm kernel oil, palm oil, hybrid sunflower oil, hybrid sunflower oil, peanut oil, pistachio seed oil, castor oil, sunflower seed oil, sunflower oil, grape seed oil, hazelnut seed oil, hazelnut oil, jojoba seed oil, Macadamia ternifolia seed oil, macadamia nut oil, mango seed oil, meadowfoam oil, peach kernel oil, coconut oil, peanut oil, borage seed oil, rosehip oil, Moringa oleifera seed oil, and the like. One of these components B may be used alone, or two or more thereof may be appropriately combined and used.

[0020] Among the above components B, from the viewpoint of significantly reducing the raw material odor of the above component A, it is preferable to use at least one selected from the group consisting of evening primrose oil, Camellia japonica seed oil, meadowfoam oil, corn oil, rice germ oil, jojoba seed oil and olive fruit oil, and it is more preferable to use at least one selected from the group consisting of meadowfoam oil, corn oil, rice germ oil, jojoba seed oil and olive fruit oil.

[0021] In addition, the aforementioned component B is not particularly limited whether it is a single raw material or a mixed raw material with other components, as long as the desired effect is exerted. In the present invention, commercially available products can be used as the aforementioned component B. Examples of commercially available meadowfoam oil include CROPURE MEADOWFOAM-LQ-(JP) (trade name, manufactured by Croda Japan Co., Ltd.). Examples of commercially available corn oil include NIKKOL Corn Germ Oil (trade name, manufactured by Nikko Chemicals Co., Ltd.). Examples of commercially available rice germ oil include Oryza Oil S-1 (trade name, manufactured by Oryza Oil & Chemical Co., Ltd.). Examples of commercially available jojoba seed oil include NIKKOL Jojoba Oil S (trade name, manufactured by Nippon Surfactant Industries Co., Ltd.). Examples of commercially available olive fruit oil include NIKKOL Olive Oil (trade name, manufactured by Nikko Chemicals Co., Ltd.).

[0022] The content of component B in the emulsified composition for skin of the present invention is not particularly limited as long as the desired effect is sufficiently exerted. Usually, from the viewpoint of significantly reducing the raw material odor of the aforementioned component A, it is preferably 0.01% by mass or more, more preferably 0.1% by mass or more, based on 100% by mass of the composition. In addition, from the viewpoint of usability, the content is preferably 15% by mass or less, more preferably 10% by mass or less, based on 100% by mass of the composition. The content of the aforementioned component B is an amount converted to the pure content.

[0023] In the present invention, from the viewpoint of significantly reducing the raw material odor of the aforementioned component A, the ratio of the content of the aforementioned component B to the aforementioned component A (component B / component A) preferably satisfies the range of 0.01 to 150, more preferably satisfies the range of 0.02 to 50, still more preferably satisfies the range of 0.1 to 20, and most preferably satisfies the range of 0.2 to 12.

[0024] [Component C] The above component C is a polyglycerin fatty acid ester type nonionic surfactant. In the present invention, by emulsifying the composition using the above component C, excellent formulation stability, or so-called emulsification stability, can be imparted. In the present invention, because of the good formulation stability, the raw material odor reduction effect of the above component A can be stably maintained.

[0025] The number of carbon atoms in the fatty acids constituting the polyglycerin fatty acid ester of component C is not particularly limited, but is preferably 8 to 24, more preferably 10 to 20, and even more preferably 12 to 18. Furthermore, the fatty acid portion is not particularly limited as long as the desired effect is sufficiently exhibited, whether it is a saturated fatty acid or an unsaturated fatty acid, but it is preferable that it be an unsaturated fatty acid from the viewpoint of enhancing the raw material odor reduction effect of component A by providing excellent formulation stability. On the other hand, the average degree of polymerization of the polyglycerin constituting the polyglycerin fatty acid ester is not particularly limited, but is preferably 2 to 12, and more preferably 5 to 10.

[0026] Examples of polyglycerol fatty acid esters of component C include monoesters, diesters, and triesters. Specifically, component C may include polyglycerol fatty acid monoesters, polyglycerol fatty acid diesters, and polyglycerol fatty acid triesters. Component C may also be a mixture of these.

[0027] Examples of the above-mentioned component C that can be used include hexaglyceryl monomyristate, decaglyceryl monostearate, decaglyceryl monoisostearate, decaglyceryl monooleate, decaglyceryl monolinoleate, decaglyceryl monocaprate, decaglyceryl monolaurate, decaglyceryl monomyristate, decaglyceryl dioleate, decaglyceryl distearate, decaglyceryl diisostearate, pentaglyceryl monolaurate, pentaglyceryl dioleate, hexaglyceryl monocaprylate, triglyceryl monocaprylate, poly(4-10)glyceryl monolaurate, poly(2-10)glyceryl monostearate, poly(2-10)glyceryl diisostearate, and poly(2-10)glyceryl monooleate. These components C may be used individually or in combination of two or more as appropriate.

[0028] Among the above-mentioned components C, it is preferable to use decaglyceryl monooleate, decaglyceryl monostearate, decaglyceryl diisostearate, decaglyceryl monolinoleate, decaglyceryl dioleate, pentaglyceryl dioleate, or poly(2-10)glyceryl monooleate, from the viewpoint of improving formulation stability and further enhancing the raw material odor reduction effect of the above-mentioned component A. It is even more preferable to use decaglyceryl monooleate, decaglyceryl monostearate, or decaglyceryl diisostearate.

[0029] Furthermore, the above-mentioned component C is not particularly limited, whether it is a single raw material or a mixed raw material with other components, as long as the desired effect is achieved. In the present invention, the above-mentioned component C can be a commercially available product. Examples of commercially available products of decaglyceryl monooleate include Decaglyn 1-OV (trade name, manufactured by Nippon Surfactant Industry Co., Ltd.) and Sunsoft Q-17Y-C (trade name, manufactured by Taiyo Kagaku Co., Ltd.). Examples of commercially available products of decaglyceryl monostearate include Decaglyn 1-SV (trade name, manufactured by Nippon Surfactant Industry Co., Ltd.) and Sunsoft Q-18Y-C (trade name, manufactured by Taiyo Kagaku Co., Ltd.). Examples of commercially available products of decaglyceryl diisostearate include NIKKOL Decaglyn 2-ISV (trade name, manufactured by Nippon Surfactant Industry Co., Ltd.).

[0030] The content of component C in the skin emulsifying composition of the present invention is not particularly limited as long as the desired effect is sufficiently achieved. However, from the viewpoint of providing formulation stability and further improving the effect of reducing the raw material odor by component A, it is preferably 0.1% by mass or more, and more preferably 0.2% by mass or more, per 100% by mass of the composition. Furthermore, from the viewpoint of usability, it is preferably 2% by mass or less, and more preferably 1.2% by mass or less, per 100% by mass of the composition. Note that the content of component C is the amount converted to pure content.

[0031] The skin emulsifying composition of the present invention, by combining components A, B, and C described above, exhibits exceptionally superior formulation stability and reduces the odor of the raw materials. Therefore, it is also possible to separately incorporate a specific functional component (hereinafter referred to as component D) that has an odor from the raw materials.

[0032] [Component D] The above component D is at least one selected from the group consisting of hydrolyzed hyaluronic acid, hyaluronic acid salts, and hyaluronic acid derivatives. Hyaluronic acid is a high molecular weight polysaccharide compound in which disaccharides consisting of glucosidic bonds between N-acetyl-D-glucosamine and D-glucuronic acid are repeated units, and it is a component that has a slightly peculiar odor.

[0033] In the present invention, hydrolyzed hyaluronic acid is obtained by reducing the molecular weight of the above-mentioned hyaluronic acid. Examples of hyaluronic acid salts include sodium salts, potassium salts, and basic amino acid salts. Examples of hyaluronic acid derivatives include acetylated hyaluronic acid, which is obtained by acetylating hyaluronic acid; hyaluronic acid propylene glycol ester, which is obtained by esterifying the carboxyl group at position 6 of the D-glucuronic acid of hyaluronic acid with propylene glycol; and salts of these hyaluronic acid derivatives. These components D may be used individually or in appropriate combinations of two or more.

[0034] Furthermore, the above-mentioned component D is not particularly limited as long as the desired effect is achieved, whether as a single raw material or a mixed raw material with other components. In the present invention, the above-mentioned component D can be a commercially available product. Examples of commercially available hydrolyzed hyaluronic acid include Hyalo-Oligo (product name, manufactured by Kewpie Corporation). Examples of commercially available sodium hyaluronate include Hyaluronsan HA-LQ (product name, manufactured by Kewpie Corporation), Hyaluronic Acid FCH-60, 80, 120, 150, 200 (product names, all manufactured by Kikkoman Biochemifa Co., Ltd.). Examples of commercially available acetylated sodium hyaluronate include acetylated sodium hyaluronate (product name, manufactured by Shiseido Corporation).

[0035] The content of component D in the skin composition of the present invention is not particularly limited as long as the desired effect is sufficiently achieved. However, from the viewpoint of further enhancing sustained moisture, it is generally preferable to have 0.0001% by mass or more, and more preferably 0.001% by mass or more, per 100% by mass of the composition. Furthermore, from the viewpoint of preventing stickiness, it is preferable to have 0.5% by mass or less, and more preferably 0.1% by mass or less, per 100% by mass of the composition. Note that the above content of component D is the amount converted to pure content.

[0036] The skin emulsifying composition of the present invention may further contain a thickening polymer from the viewpoint of enhancing formulation stability (emulsification stability). Examples of thickening polymers include water-soluble natural polymers, semi-synthetic polymers, and synthetic polymers. In this specification, the thickening polymer may be referred to as component E.

[0037] Examples of component E include natural polymers such as gum arabic, tragacanth gum, guar gum, locust bean gum, karaya gum, xanthan gum, iris moss, quince seed, gelatin, shellac, rosin, and casein; semi-synthetic polymers such as sodium carboxymethylcellulose, hydroxyethylcellulose, methylcellulose, ethylcellulose, sodium alginate, ester gum, nitrocellulose, hydroxypropylcellulose, hydroxypropylmethylcellulose, and crystalline cellulose; and synthetic polymers such as polyvinyl alcohol, sodium polyacrylate, carboxyvinyl polymer, (acrylates / alkyl acrylate (C10-30)) crosspolymer (acrylate / alkyl methacrylate copolymer), polyvinyl methylcellulose, and polyamide resin. These components G may be used individually or in appropriate combinations of two or more.

[0038] The content of component G in the skin composition of the present invention is not particularly limited, but from the viewpoint of improving storage stability (emulsification stability), it is preferably 0.01% by mass or more, and more preferably 0.1% by mass or more, per 100% by mass of the composition. Furthermore, from the viewpoint of usability, it is preferably 2.0% by mass or less, and more preferably 1.0% by mass or less, per 100% by mass of the composition. Note that the content of component E above is the amount converted to pure content.

[0039] [Other ingredients] In addition to the above-mentioned components, the skin emulsifying composition of the present invention may contain, as long as it does not impair the effects of the present invention, oils such as fats and oils, waxes, hydrocarbon oils, higher fatty acids, higher alcohols, fatty acid ester oils, and silicone oils; surfactants such as anionic surfactants, cationic surfactants, amphoteric surfactants, and nonionic surfactants other than component C; divalent or trivalent polyhydric alcohols; film-forming agents, sugar alcohols, UV absorbers, whitening agents, anti-inflammatory agents, cooling agents, pH adjusters, neutralizing agents, fragrances, etc., as appropriate depending on the purpose.

[0040] The remainder of the skin composition of the present invention is purified water. The amount of purified water is not particularly limited, but from the viewpoint of storage stability, it is preferably 30 to 95% by mass, and more preferably 50 to 90% by mass.

[0041] The method for producing the skin emulsifying composition of the present invention is not particularly limited, but can be produced by known methods, for example. Specifically, this could involve mixing the above-mentioned components and emulsifying them by known methods, such as a phase inversion emulsification method using a homomixer, but the present invention is not limited to these production methods.

[0042] The use of the skin emulsifying composition according to one embodiment of the present invention is not particularly limited, but it is preferably used as a skin cosmetic, and more specifically, it is preferably used as a moisturizing cosmetic, a whitening cosmetic, an acne care cosmetic, or an anti-aging cosmetic for purposes such as wrinkle suppression and sagging suppression. Furthermore, the skin emulsifying composition of the present invention may take the form of cosmetics, quasi-drugs, designated quasi-drugs, general merchandise, etc.

[0043] Furthermore, the areas to which the skin emulsified composition according to one embodiment of the present invention is applied are not particularly limited, but as an example, it can be used on the face (forehead, around the eyes, corners of the eyes, cheeks, around the mouth, etc.), arms, elbows, back of the hands, fingertips, feet, knees, heels, neck, décolleté, armpits, back, etc. [Examples]

[0044] The present invention will be described in more detail below based on examples, but the present invention is not limited to these examples. Unless otherwise specified, the amounts of each ingredient are expressed in "mass%".

[0045] (Sample preparation 1) According to the compositions listed in Tables 1 and 2, the skin emulsifier compositions of Examples 1-9 and Comparative Examples 1-4 were prepared into emulsifier forms according to conventional methods and subjected to the following evaluation. The results are shown in Tables 1 and 2. Note that all amounts in the tables are converted to pure content.

[0046] (Test Example 1: Evaluation of Formulation Stability) Each sample from the examples and comparative examples was sealed in a 50 mL transparent glass container and stored in a 0°C constant temperature bath for 4 weeks. Afterward, the emulsifier type was visually observed and evaluated according to the following evaluation criteria.

[0047] <Evaluation Criteria for Formulation Stability> ◎ (Excellent): No change whatsoever is observed compared to immediately after manufacturing. ○ (Good): Although a very slight change in viscosity is observed, there is almost no change. △ (Insufficient): A clear change in viscosity is observed. × (Defective): Has changed into a liquid state or has separated.

[0048] (Test Example 2: Evaluation of the presence or absence of raw material odor) Each sample from the examples and comparative examples was sealed in a 50 mL transparent glass container and stored in a 0°C constant temperature bath for 4 weeks. After storage, 1 g of each sample was applied to the back of the hand, and the presence or absence of a raw material odor caused by component A was evaluated by sensory assessment based on the odor released when spread. The evaluation was conducted by 10 expert panelists, and the judgment was made based on whether or not they could detect the raw material odor of component A that they smelled before the evaluation.

[0049] <Evaluation Criteria for Raw Material Odor> ◎ (Very Good): 9-10 out of 10 people reported not noticing any raw material odor caused by ingredient A. ○ (Good): 6 to 8 out of 10 people reported not noticing any raw material odor caused by component A. △ (Insufficient): Out of 10 people, 3 to 5 responded that they did not detect any raw material odor caused by component A. × (Poor): Out of 10 people, 1-2 reported not detecting any raw material odor caused by ingredient A.

[0050] [Table 1]

[0051] [Table 2]

[0052] The results shown in Tables 1 and 2 indicate that the skin emulsifying compositions obtained in each example, despite containing a high concentration of coenzyme Q10 compared to those obtained in each comparative example, significantly reduced the raw material odor caused by coenzyme Q10 and exhibited excellent formulation stability.

[0053] As is clear from these results, the skin emulsifying composition of the present invention satisfies both of the following effects, which were difficult to achieve in conventional attempts: significantly reducing the raw material odor caused by coenzyme Q10 despite containing a high concentration of coenzyme Q10, and exhibiting excellent formulation stability.

Claims

1. Component A: Coenzyme Q10 and Ingredient B: Naturally derived vegetable oils and Ingredient C: Polyglycerin fatty acid ester type nonionic surfactant and It contains, The content of component A is greater than 0.3% by mass and less than or equal to 1% by mass. A skin emulsifying composition characterized by the use of decaglyceryl monooleate and decaglyceryl monostearate as polyglycerin fatty acid ester type nonionic surfactants.

2. The skin emulsifying composition according to claim 1, wherein component B is at least one selected from the group consisting of meadowfoam oil, corn oil, rice germ oil, jojoba seed oil, and olive fruit oil.

3. The skin emulsifying composition according to claim 1 or 2, wherein the content of component B is 0.01% by mass or more and 15% by mass or less.

4. A skin emulsifying composition according to any one of claims 1 to 3, further comprising the following component D. Component D: At least one selected from the group consisting of hydrolyzed hyaluronic acid, hyaluronic acid salts, and hyaluronic acid derivatives.

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