Method for controlling disease-transmitting insects using condensed heterocyclic compound

Abstract

The present invention provides a method for controlling disease-transmitting insects. The method comprises using an aerosol agent to treat disease-transmitting insects, places through which disease-transmitting insects can pass, and places where disease-transmitting insects can live, said aerosol agent containing a propellant and at least one compound selected from the group consisting of a compound represented by formula (I) [where R1 represents a C1-C3 haloalkoxy group, a C1-C3 haloalkylthio group, a C1-C3 haloalkylsulfinyl group, or a C1-C3 haloalkylsulfonyl group, and R2 represents a hydrogen atom or a cyano group], an N-oxide thereof, and a salt thereof.

Description

Method for controlling sanitary pests using fused heterocyclic compounds

[0001] This patent application claims priority under the Paris Convention to and the benefit of Japanese Patent Application No. 2021-071589 (filed April 21, 2021) and Japanese Patent Application No. 2021-123405 (filed July 28, 2021), the entire contents of which are incorporated herein by reference.

[0002] The present invention relates to a method for controlling sanitary pests using an aerosol agent containing a certain fused heterocyclic compound.

[0003] Patent Documents 1 to 4 disclose fused heterocyclic compounds having insecticidal activity.

[0004] International Publication No. 2017 / 146226 International Publication No. 2020 / 175491 Japanese Patent Application Laid-Open No. 2014-5263 Japanese Patent Application Laid-Open No. 2016-506360

[0005] The present invention provides a method more suitable for controlling sanitary pests as a household or commercial insecticide.

[0006] The present invention includes, but is not limited to, the following embodiments: [1] Formula (I): [In the formula, R １ represents a C1-C3 haloalkoxy group, a C1-C3 haloalkylthio group, a C1-C3 haloalkylsulfinyl group, or a C1-C3 haloalkylsulfonyl group, and R ２ represents a hydrogen atom or a cyano group. ] (hereinafter referred to as "compound (I)"), or at least one compound selected from the group consisting of an N-oxide thereof or a salt thereof (hereinafter referred to as "the compound"), and a propellant (hereinafter referred to as "the aerosol of the present invention"). [2] The aerosol is a compound represented by formula (I), wherein R １ is a trifluoromethylsulfinyl group or a trifluoromethylsulfonyl group, and R ２is a hydrogen atom. [3] The sanitary pest control method according to the preceding paragraph [1], wherein the aerosol is an aerosol containing a compound in which R is a hydrogen atom. [4] The sanitary pest control method according to any one of the preceding paragraphs [1] to [3], wherein the aerosol further contains a hydrocarbon solvent. [5] The sanitary pest control method according to any one of the preceding paragraphs [1] to [4], wherein the aerosol further contains water. [6] The sanitary pest control method according to any one of the preceding paragraphs [1] to [5], wherein the aerosol further contains at least one insecticidal active ingredient. [7] The at least one insecticidal active ingredient is allethrin, bioallethrin, bioresmethrin, dimefluthrin, empenthrin, epsilonmetofluthrin, epsilonmomfluorothrin, flumethrin, meperfluthrin, metofluthrin, momfluorothrin, prallethrin, profluthrin, resmethrin, tetramethrin, tetramethylfluthrin, transfluthrin, imiprothrin, heptafluthrin, permethrin, fenothrin, cyphenothrin, cypermethrin, cyfluthrin, etofenprox [8] The sanitary pest control method according to any one of the preceding items [1] to [7], wherein the sanitary pest is at least one sanitary pest selected from the group consisting of methicillin-containing insects, deltamethrin, fenpropathrin, furamethrin, pyrethrins, acetamiprid, clothianidin, dinotefuran, imidacloprid, thiamethoxam, thiacloprid, indoxacarb, brofuranilide, fenitrothion, cyphenothrin, sulfoxaflor, pyriproxyfen, piperonyl butoxide, and N-(2-ethylhexyl)-8,9,10-trinorborn-5-ene-2,3-dicarboximide. [9] The sanitary pest control method according to any one of the preceding items [1] to [7], wherein the sanitary pest is at least one sanitary pest selected from the group consisting of Blattolatrix, Hymenoptera, Diptera, Siphonaptera, Acarina, Lepidoptera, and Coleoptera. [9] The aerosol according to any one of the preceding items [1] to [6].

[10] The aerosol according to the preceding item [9], wherein the aerosol contains liquefied petroleum gas as a propellant.

[11] The aerosol according to

[10] , which comprises, per weight of the aerosol, 0.01 to 5 parts by weight of the compound of formula (1), 30 to 90 parts by weight of liquefied petroleum gas, and 20 to 70 parts by weight of a hydrocarbon solvent.

[12] The aerosol according to any one of the preceding items [9],

[10] , and

[11] , filled in a pressure-resistant container.

[13] An aerosol product obtained by filling a pressure-resistant container with the aerosol according to any one of the preceding items [9],

[10] , and

[11] .

[0007] According to the present invention, by using an aerosol, it is possible to apply the active ingredient in the desired amount to the desired location without waste. According to the present invention, the aerosol product can be easily used by simply pressing a button or turning a valve installed on a pressure-resistant container containing the aerosol. The aerosol is completely sealed, so there is no need to worry about contamination of the surrounding area, and it is highly effective and suitable for exterminating sanitary pests.

[0008] The present compound used in the sanitary pest control method of the present invention (hereinafter referred to as the "method of the present invention") will be described below.

[0009] Substituent R in Compound (I) １Examples of C1-C3 haloalkoxy groups include trifluoromethyl, difluoromethyl, 2,2,2-trifluoroethyl, 1,1,2,2-tetrafluoroethyl, pentafluoroethyl, heptafluoropropyl, and 2,2,3,3,3-pentafluoropropyl groups. Examples of C1-C3 haloalkylthio groups include trifluoromethylthio, difluoromethylthio, 2,2,2-trifluoroethylthio, 1,1,2,2-tetrafluoroethylthio, pentafluoroethylthio, heptafluoropropylthio, and 2,2,3,3,3-pentafluoropropylthio groups. Examples of C1-C3 haloalkylsulfinyl groups include trifluoromethylsulfinyl, difluoromethylsulfinyl, 2,2,2-trifluoroethylsulfinyl, 1,1,2,2-tetrafluoroethylsulfinyl, pentafluoroethylsulfinyl, heptafluoropropylsulfinyl, and 2,2,3,3,3-pentafluoropropylsulfinyl. Examples of C1-C3 haloalkylsulfonyl groups include trifluoromethylsulfonyl, difluoromethylsulfonyl, 2,2,2-trifluoroethylsulfonyl, 1,1,2,2-tetrafluoroethylsulfonyl, pentafluoroethylsulfonyl, heptafluoropropylsulfonyl, and 2,2,3,3,3-pentafluoropropylsulfinyl.

[0010] The N-oxide of compound (I) is represented by formula (II): (In the formula, R １ and R ２ is as defined above.) (hereinafter referred to as "compound (II)").

[0011] Compound (I) and compound (II) include R １ is a trifluoromethylsulfinyl group or a trifluoromethylsulfonyl group, and R ２ is preferably a compound in which is a hydrogen atom.

[0012] The present compound may exist in one or more stereoisomers. Stereoisomers include enantiomers and diastereomers. The present compound includes each stereoisomer and a mixture of stereoisomers in any ratio.

[0013] The present compound may form an acid addition salt. Examples of acids that form acid addition salts include inorganic acids such as hydrogen chloride, phosphoric acid, and sulfuric acid, and organic acids such as acetic acid, trifluoroacetic acid, benzoic acid, and p-toluenesulfonic acid. The acid addition salt can be obtained by mixing the present compound with an acid.

[0014] The present compound may be exemplified by the following compounds, but is not limited to these compounds.

[0015] [Aspect 1] R １ is a C1-C3 haloalkylsulfinyl group or a C1-C3 haloalkylsulfonyl group, and R ２ is a hydrogen atom. 1 is a C1-C3 haloalkylsulfinyl group, and R 2 is a hydrogen atom. 1 is a C1-C3 haloalkylsulfonyl group, and R 2 is a hydrogen atom. 1 is a trifluoromethylsulfinyl group or a trifluoromethylsulfonyl group, and R 2 is a hydrogen atom. 1 is a trifluoromethylsulfinyl group, and R 2 is a hydrogen atom. 1 is a trifluoromethylsulfonyl group, and R 2 is a hydrogen atom.

[0016] Next, the method for producing the present compound will be explained.

[0017] Compound (I) can be produced, for example, according to the methods described in WO2016 / 121997, WO2017 / 146226, and WO2020 / 117487.

[0018] (Production Method 1) Compound (II) can be produced by reacting compound (I) with an oxidizing agent. The reaction is usually carried out in the presence of a solvent. Examples of solvents used in the reaction include halogenated hydrocarbons such as dichloromethane and chloroform (hereinafter referred to as halogenated hydrocarbons); nitriles such as acetonitrile (hereinafter referred to as nitriles); acetic acid; water; and mixtures of two or more of these. Examples of oxidizing agents used in the reaction include sodium periodate, m-chloroperbenzoic acid, and hydrogen peroxide. When hydrogen peroxide is used as the oxidizing agent, a base or catalyst may be added as necessary. Examples of bases used in the reaction include sodium carbonate. When a base is used in the reaction, the base is usually used in a ratio of 0.01 to 1 mole per mole of compound (I). Examples of catalysts used in the reaction include sodium tungstate. When a catalyst is used in the reaction, the catalyst is usually used in a ratio of 0.01 to 0.5 moles per mole of compound (I). In the reaction, an oxidizing agent is typically used in a ratio of 1 to 2 moles per mole of compound (I). The reaction temperature is typically in the range of -20 to 120°C. The reaction time is typically in the range of 0.1 to 12 hours. After completion of the reaction, water is added to the reaction mixture, which is then extracted with an organic solvent. The organic layer is washed, as necessary, with an aqueous solution of a reducing agent (e.g., sodium sulfite, sodium thiosulfate) and an aqueous solution of a base (e.g., sodium bicarbonate). Compound (II) can be obtained by drying and concentrating this organic layer.

[0019] Examples of compounds prepared according to any of the processes described herein are shown below.

[0020] In compound (I), R １ and R ２ is a combination of any of the substituents described in [Table S1] and [Table S2] (hereinafter referred to as compound group SX1). １ and R ２ is a combination of any of the substituents described in [Table S1] and [Table S2] (hereinafter referred to as compound group SX2).

[0021] The aerosol formulation used in the method of the present invention typically contains the present compound and a propellant and is filled into a pressure-resistant container for use. An aerosol product, in which the aerosol formulation is filled into a pressure-resistant container, is a device that sprays the filled compound in a mist form using the pressure of the propellant. The aerosol product can be produced, for example, by filling a pressure-resistant container with an aerosol formulation containing the present compound, a solvent, water, and optionally other insecticidal active compounds, repellents, synergists, stabilizers, fragrances, etc., and then attaching an aerosol valve to the container. The propellant is then poured into the container through the stem, shaken, and then attached to an actuator. Alternatively, the aerosol product can be produced by simultaneously sealing the present compound, optional auxiliary components such as solvents, and the propellant into a pressure-resistant container. The aerosol valve is not particularly limited, and valves with various orifice diameters can be selected as needed. Examples of actuators include button-type and trigger-type actuators.

[0022] The pressure vessel is not particularly limited in terms of material or capacity, but examples include pressure vessels of 0.01 to 50 liters made of materials such as iron, aluminum, stainless steel, and plastic.

[0023] The content of the present compound in the aerosol used in the method of the present invention is usually 0.001 to 10% by weight, preferably 0.01 to 1% by weight, of the total amount of the aerosol (comprising the present compound, propellant, and at least one component selected from the group consisting of solvent, water, other insecticidal active ingredient, repellent, synergist, stabilizer, and fragrance, which may be used appropriately in addition to these components).

[0024] The propellant contained in the aerosol used in the method of the present invention generally includes liquefied gas. Examples of liquefied gas include liquefied petroleum gas, mixtures of C3-C4 hydrocarbons such as propane, propylene, normal butane, and isobutane, dimethyl ether, and carbon dioxide. These gases may be used alone or in combination of two or more.

[0025] In the aerosol used in the method of the present invention, the propellant is contained in an amount of 10 to 99% by weight, preferably 20 to 95% by weight, more preferably 25 to 90% by weight, of the total amount of ingredients to be filled (the present compound, the propellant, and optionally at least one ingredient selected from the group consisting of solvents, water, other insecticidal active ingredients, repellents, synergists, stabilizers, and fragrances).

[0026] A solvent may be added to the aerosol formulation used in the method of the present invention, if necessary. Examples of solvents include linear or branched chain saturated hydrocarbon solvents having 10 to 18 carbon atoms, alicyclic saturated hydrocarbon solvents, and aromatic solvents. Examples of chain saturated hydrocarbons having 10 to 18 carbon atoms include decane, undecane, dodecane, tridecane, tetradecane, pentadecane, and 2-methyldecane. Examples of alicyclic hydrocarbons having 10 to 18 carbon atoms include cyclodecane and decalin. Examples of aromatic solvents include methylnaphthalene, naphthalene, and phenylxylylethane. If necessary, a solvent with a smaller carbon number may be added appropriately to reduce wetting of the spray surface.

[0027] Specific examples of the linear or branched chain saturated hydrocarbon solvents and alicyclic saturated hydrocarbon solvents are listed below, but the solvents are not limited to these specific examples. Examples of linear saturated hydrocarbon solvents include Neothiozol (trade name, Chuo Kasei Co., Ltd.), Norpar 12 (trade name, Exxon Mobil Corporation), Norpar 13 (trade name, Exxon Mobil Corporation), and Norpar 15 (trade name, Exxon Mobil Corporation); examples of branched saturated hydrocarbon solvents include Isopar E (trade name, Exxon Mobil Corporation), Isopar G (trade name, Exxon Mobil Corporation), Isopar H (trade name, Exxon Mobil Corporation), Isopar M (trade name, Exxon Mobil Corporation), Isopar V (trade name, Exxon Mobil Corporation), and IP-2028 (trade name, Idemitsu Petrochemical Co., Ltd.); and examples of alicyclic saturated hydrocarbon solvents include Exxon Mobil Corporation, Exxon Mobil Corporation, Exxon Mobil Corporation, Exxon Mobil Corporation, Exxon Mobil Corporation, Exxon Mobil Corporation, Exxon Mobil Corporation, and Exxon Mobil Corporation. Examples of aromatic solvents include Solvesso 200 (trade name, Exxon Mobil Corporation), Solvesso 150 (trade name, Exxon Mobil Corporation), and phenylxylylethane (trade name, Asahi Petrochemical Co., Ltd.).

[0028] Furthermore, the aerosol agent used in the method of the present invention may contain a solubility aid such as an ester-based solvent or an alcohol-based solvent, if necessary.

[0029] Examples of ester-based solvents include ester-based solvents having 12 to 30 carbon atoms. Specific examples include alkyl esters of 12 to 30 carbon atoms, and more specific examples include alkyl esters of alkyl carboxylates having 12 to 30 carbon atoms, such as isopropyl myristate, hexyl laurate, and isopropyl palmitate; dialkyl esters of dicarboxylates having 12 to 30 carbon atoms, such as diisopropyl adipate, dioctyl adipate, diisononyl adipate, and diisodecyl adipate; trialkyl acetyl citrates having 12 to 30 carbon atoms, such as triethyl acetyl citrate and tributyl acetyl citrate; trialkyl citric acid esters having 12 to 30 carbon atoms, such as triethyl citrate; and dialkyl phthalates having 12 to 30 carbon atoms, such as dibutyl phthalate and diisononyl phthalate.

[0030] More preferred examples of the ester solvent include alkyl esters of alkyl carboxylates having 12 to 30 carbon atoms, dialkyl esters of dicarboxylates having 12 to 30 carbon atoms, trialkyl acetyl citrates having 12 to 30 carbon atoms, trialkyl citric acid esters having 12 to 30 carbon atoms, and dialkyl phthalates having 12 to 30 carbon atoms, and even more preferred examples include alkyl esters of alkyl carboxylates having 12 to 30 carbon atoms, dialkyl esters of dicarboxylates having 12 to 30 carbon atoms, and trialkyl acetyl citrates having 12 to 30 carbon atoms.

[0031] Specific examples of the ester solvent include ethyl acetate, butyl acetate, amyl acetate, isoamyl acetate, isobornyl acetate, hexyl acetate, heptyl acetate, octyl acetate, isopropyl myristate, methyl octanoate, methyl oleate, methyl laurate, dibutyl adipate, diisopropyl adipate, dioctyl adipate, diisononyl adipate, diisodecyl adipate, tributyl citrate, triethyl acetylcitrate, tributyl acetylcitrate, ethyl lactate, propyl lactate, ethylene carbonate, propylene carbonate, butylene carbonate, diethyl carbonate, and dibutyl carbonate.

[0032] Specific examples of the alcohol-based solvent include methanol, ethanol, butanol, propanol, isopropanol, butanol, amyl alcohol, hexanol, heptanol, octanol, 2-ethylhexanol, hexylene glycol, cyclohexanol, phenol, benzyl alcohol, methoxypropanol (1-methoxy-2-propanol), tetrahydrofurfuryl alcohol, furfuryl alcohol, polyethylene glycol, ethylene glycol, diethylene glycol, hexylene glycol, ethylene glycol methyl ether, diethylene glycol methyl ether, diethylene glycol butyl ether, triethylene glycol, propylene glycol methyl ether, dipropylene glycol, ethylene glycol monomethyl ether, ethylene glycol monoethyl ether, ethylene glycol butyl ether, dipropylene glycol methyl ether, dipropylene glycol ether, dipropylene glycol monomethyl ether, and glycerin.

[0033] The aerosol formulation used in the method of the present invention may contain water as a solvent, if necessary. Water is usually added in an amount 40 to 1000 times by weight of the present compound. In the aerosol formulation used in the method of the present invention, one solvent may be used alone, or two or more solvents may be used in combination.

[0034] When water is used as the solvent, a surfactant may be added as necessary. Examples of surfactants include nonionic surfactants, anionic surfactants, cationic surfactants, and amphoteric surfactants, and are not particularly limited thereto. However, among these, nonionic surfactants are preferred from the viewpoint of safety. Examples of nonionic surfactants include higher fatty acid esters of sorbitan, particularly C12-C18 fatty acid monoesters of sorbitan and C12-C18 fatty acid diesters of sorbitan (e.g., sorbitan monooleate, sorbitan dioleate, sorbitan monolaurate, sorbitan monostearate, sorbitan distearate, sorbitan monoisostearate, and sorbitan monopalmitate).

[0035] In the aerosol used in the present invention, the content of the nonionic surfactant is 0.1 to 5% by weight based on the total amount of the components of the aerosol (e.g., the present compound, the propellant, and at least one component selected from the group consisting of solvents, water, other insecticidal active ingredients, repellents, synergists, stabilizers, and fragrances, which may be used as other optional components).

[0036] The aerosol formulation used in the present invention may further contain one or more other insecticidally active compounds, repellents, synergists, etc. Examples of combinations of the present compound with other insecticidally active compounds, repellents, and synergists are listed below. For example, alanycarb + SX refers to a combination of alanycarb with each of the SXs listed in the table above. More specifically, the abbreviation SX refers to any one of the present compounds selected from the compound groups SX1 and SX2 listed in the table above. The other insecticidally active compounds, repellents, and synergists listed below are all known components and can be obtained from commercially available formulations or prepared by known methods.

[0037] Combinations of this compound with other insecticidal active compounds: abamectin + SX, acephate + SX, acequinocyl + SX, acetamiprid + SX, acetoprole + SX, acrinathrin + SX, acinonapyr + SX, afidopyropen + SX, afoxolaner + SX, alanycarb + SX, aldicarb + SX, allethrin + SX, alpha-cypermethrin + SX, alpha-endosulfan + SX, aluminum phosphide + SX. Amitraz + SX, azadirachtin + SX, azamethiphos + SX, azinphos-ethyl + SX, azinphos-methyl + SX, azocyclotin + SX, Celastrus angulatus bark + SX, bendiocarb + SX, benfluthrin + SX, benfuracarb + SX, bensultap + SX, benzoximate + SX, benzpyrimoxan + SX, beta-cyfluthrin + SX, beta-cypermethrin + SX, bifenazate + SX, bifenthrin + SX, bioallethrin + SX,Bioresmethrin + SX, bistrifluron + SX, borax + SX, boric acid + SX, broflanilide + SX, bromopropylate + SX, buprofezin + SX, butocarboxim + SX, butoxycarboxim + SX, cadusafos + SX, calcium phosphide + SX, carbaryl + SX, carbofuran + SX, carbosulfan + SX, cartap hydrochloride + SX, cartap + SX Cevadine + SX, chinomethionate + SX, chlorantraniliprole + SX, chlordane + SX, chlorethoxyfos + SX, chlorfenapyr + SX, chlorfenvinphos + SX, chlorfluazuron + SX, chlormephos + SX, chloropicrin + SX, chlorpyrifos + SX, chlorpyrifos-methyl + SX, chromafenozide + SX, clofentezine + SX, clothianidin + SX, concanamycin A + SX, coumaphos + SX, cryolite + SX, cyanophos + SX,Cyantraniliprole + SX, cyclaniliprole + SX, cyclobutrifluram + SX, cycloprothrin + SX, cycloxaprid + SX, cyenopyrafen + SX, cyetpyrafen + SX, cyflumetofen + SX, cyfluthrin + SX, cyhalodiamide + SX, cyhalothrin + SX, cyhexatin + SX, cypermethrin + SX, cyphenothrin + SX, cyproflanilide + SX, cyromazine + SX, dazomet + SX, deltamethrin + SX, demeton-S-methyl + SX, diafenthiuron + SX, diazinon + SX, dichlorvos + SX, dichloromezotiaz + SX, dicofol + SX, dicrotophos + SX, diflovidazin + SX, diflubenzuron + SX, dimefluthrin + SX, dimethoate + SX, dimethylvinphos + SX, Dimpropyridaz + SX, dinotefuran + SX, disodium octaborate + SX, disulfoton + SX, DNOC (2-methyl-4,6-dinitrophenol) + SX,Doramectin + SX, dried leaves of Dryopteris filix (mas) + SX, emamectin benzoate + SX, empenthrin + SX, endosulfan + SX, EPN (O-ethyl O-(4-nitrophenyl) phenylphosphonothioate) + SX, epsilon-metofluthrin + SX, epsilon-momfluorothrin + SX, esfenvalerate + SX, ethiofencarb + SX, ethion + SX, ethiprole + SX, ethoprophos + SX, Etofenprox + SX, etoxazole + SX, Artemisia absinthium extract + SX, Azadirachta indica extract + SX, Cassia nigricans extract + SX, Clitoria ternatea extract + SX, Symphytum officinale extract + SX, Chenopodium ambrosioides extract (extracts or simulated blend of Chenopodium ambrosioides) + SX, Tansy extract + SX, Urtica dioica extract + SX, Viscum album extract + SX,Tanacetum cinerariifolium extract + SX, famphur + SX, fenamiphos + SX, fenazaquin + SX, fenbutatin oxide + SX, fenitrothion + SX, fenmezoditiaz + SX, fenobucarb + SX, fenoxycarb + SX, fenpropathrin + SX, fenpyroximate + SX, fenthion + SX, fenvalerate + SX, fipronil + SX, flometoquin + SX Flonicamid + SX, fluacrypyrim + SX, fluazaindolizine + SX, fluazuron + SX, flubendiamide + SX, fluchlordiniliprole + SX, flucycloxuron + SX, flucythrinate + SX, fluensulfone + SX, flufenprox + SX, flufenoxuron + SX, flufiprole + SX, flumethrin + SX, flupentiofenox + SX, Flupyradifurone + SX, flupyrimin + SX, fluralaner + SX, fluvalinate + SX, fluxametamide + SX,Formetanate + SX, fosthiazate + SX, furamethrin + SX, furathiocarb + SX, gamma-cyhalothrin + SX, GS-omega / kappa HXTX-Hv1a peptide + SX, halfenprox + SX, halofenozide + SX, heptafluthrin + SX, heptenophos + SX, hexaflumuron + SX, hexythiazox + SX, potassium salt of hop beta acid + SX, hydramethylnon + SX, hydroprene + SX, imicyafos + SX, imidacloprid + SX, imidaclothiz + SX, imiprothrin + SX, indazapyroxamet + SX, indoxacarb + SX, isocycloseram + SX, isofenphos + SX, isoprocarb + SX, isopropyl-O-(methoxyaminothiophosphoryl) salicylate + SX, isoxathion + SX, ivermectin + SX, kadethrin + SX, kappa-tefluthrin + SX, kappa-bifenthrin + SX, kinoprene + SX,Lambda-cyhalothrin + SX, lenoremycin + SX, lepimectin + SX, lime sulfur + SX, lotilaner + SX, lufenuron + SX, machine oil + SX, malathion + SX, mecarbam + SX, meperfluthrin + SX, metaflumizone + SX, metam + SX, metham + SX, methamidophos + SX, methidathion + SX, methiocarb + SX, methomyl + SX, Methoprene + SX, methoxychlor + SX, methoxyfenozide + SX, methyl bromide + SX, metofluthrin + SX, metolcarb + SX, metoxadiazone + SX, mevinphos + SX, milbemectin + SX, milbemycin oxime + SX, momfluorothrin + SX, monocrotophos + SX, moxidectin + SX, naled + SX, nicofluprole + SX, nicotine + SX, Nicotine sulfate + SX, nitenpyram + SX, novaluron + SX, noviflumuron + SX,Chenopodium anthelminticum seed oil + SX, omethoate + SX, oxamyl + SX, oxazosulfyl + SX, oxydemeton-methyl + SX, parathion + SX, parathion-methyl + SX, permethrin + SX, phenothrin + SX, phenthoate + SX, phorate + SX, phosalone + SX, phosmet + SX, phosphamidon + SX, phosphine + SX, phoxim + SX Pirimicarb + SX, pirimiphos-methyl + SX, prallethrin + SX, profenofos + SX, profluthrin + SX, propargite + SX, propetamphos + SX, propoxur + SX, propylene glycol alginate + SX, prothiofos + SX, pyflubumide + SX, pymetrozine + SX, pyraclofos + SX, pyrethrins + SX, pyridaben + SX, pyridalyl + SX, Pyridaphenthion + SX, pyrifluquinazone + SX, pyrimidifen + SX,Pyriminostrobin + SX, pyriprole + SX, pyriproxyfen + SX, quinalphos + SX, resmethrin + SX, rotenone + SX, ryanodine + SX, sarolaner + SX, dill seed extract (Anethum graveolens) + SX, Sabadilla seed extract (Schoenocaulon spp.) + SX, selamectin + SX, sigma-cypermethrin + SX, silafluofen + SX, sodium borate + SX, sodium metaborate + SX SX, spidoxamat + SX, spinetoram + SX, spinosad + SX, spirodiclofen + SX, spiromesifen + SX, spiropidione + SX, spirotetramat + SX, sulfluramid + SX, sulfotep + SX, sulfoxaflor + SX, sulfur + SX, sulfuryl fluoride + SX, tartar emetic + SX, tau-fluvalinate + SX, tebufenozide + SX, tebufenpyrad + SX, tebupirimfos + SX, teflubenzuron + SX, tefluthrin + SX, temephos + SX,Terbufos + SX, terpene constituents of the extract of Chenopodium ambrosioides near ambrosioides + SX, tetrachlorantraniliprole + SX, tetrachlorvinphos + SX, tetradifon + SX, tetramethrin + SX, tetramethylfluthrin + SX, tetraniliprole + SX, theta-cypermethrin + SX, thiacloprid + SX, thiamethoxam + SX, thiocyclam + SX, thiodicarb + SX, Thiofanox + SX, thiometon + SX, thiosultap disodium + SX, thiosultap monosodium + SX, tioxazafen + SX, tolfenpyrad + SX, tralomethrin + SX, transfluthrin + SX, triazamate + SX, triazophos + SX, trichlorfon + SX, trifluenfuronate + SX, triflumezopyrim + SX, triflumuron + SX, trimethacarb + SX, Tyclopyrazoflor + SX, Vamidothion + SX,Veratridine + SX, wood extract of Quassia amara + SX, XMC (3,5-dimethylphenyl N-methylcarbamate) + SX, xylylcarb + SX, zeta-cypermethrin + SX, zinc phosphide + SX, 4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl]-2-methyl-N-(1-oxothietan-3-yl)benzamide (1241050-20-3) + SX, 3-methoxy-N-(5-{5-(trifluoromethyl)-5-[3-(trifluoromethyl)phenyl]-4,5-dihydro-1,2-oxazol-3-yl}indan-1-yl)propanamide (1118626-57-5) + SX, 2-({2-fluoro-4-methyl-5-[(2,2,2-trifluoroethyl)sulfinyl]phenyl}imino)-3-(2,2,2-trifluoroethyl)-1,3-thiazolidin-4-one (1445683-71-5) + SX, (2Z)-2-({2-fluoro-4-methyl-5-[(R)-(2,2,2-trifluoroethyl)sulfinyl]phenyl}imino)-3-(2,2,2-trifluoroethyl)-1,3-thiazolidin-4-one (2377084-09-6) + SX, N-{4-chloro-3-[(1-cyanocyclopropyl)carbamoyl]phenyl}-1-methyl-4-(methanesulfonyl)-3-(1,1,2,2,2-pentafluoroethyl)-1H-pyrazole-3-carboxamide (1400768-21-9) + SX, 3-(4'-fluoro-2,4-dimethyl[1,1'-biphenyl]-3-yl)-4-hydroxy-8-oxa-1-azaspiro[4.5]dec-3-en-2-one (1031385-91-7) + SX, N-[3-chloro-1-(pyridin-3-yl)-1H-pyrazol-4-yl]-2-(methanesulfonyl)propanamide (2396747-83-2) + SX, 1,4-dimethyl-2-[2-(pyridin-3-yl)-2H-indazol-5-yl]-1,2,4-triazolidine-3,5-dione (2171099-09-3) + SX, 2-isopropyl-5-[(3,4,4-trifluoro-3-buten-1-yl)sulfonyl]-1,3,4-thiadiazole (2058052-95-0) + SX, およびN-({2-fluoro-4-[(2S,3S)-2-hydroxy-3-(3,4,5-trichlorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]phenyl}methyl)cyclopropanecarboxamide + SX。,

[0038] Combinations of the present compound with repellents: anthraquinone + SX, chloralose + SX, acrep + SX, butopyronoxyl + SX, camphor + SX, d-camphor + SX, carboxide + SX, dibutyl phthalate + SX, deet + SX, dimethyl carbate + SX, dimethyl phthalate + SX, dibutyl succinate + SX, dibutyl adipate + SX, ethohexadiol + SX, hexamide + SX, icaridin + SX Methoquin-butyl + SX, methylneodecanamide + SX, 2-(octylthio)ethanol + SX, butoxypolypropylene glycol + SX, oxamate + SX, quwenzhi + SX, quyingding + SX, zengxiaon + SX, rebemide + SX, copper naphthenate + SX, and zinc naphthenate + SX.

[0039] Combinations of the present compound with synergists: 1-dodecyl-1H-imidazole + SX, N-(2-ethylhexyl)-8,9,10-trinorborn-5-ene-2,3-dicarboximide + SX, bucarpolate + SX, N,N-dibutyl-4-chlorobenzenesulfonamide + SX, dietholate + SX, diethylmaleate + SX, piperonyl butoxide + SX, piperonyl cyclonene + SX, Piprotal + SX, propyl isome + SX, safroxan + SX, sesamex + SX, sesamolin + SX, sulfoxide + SX, verbutin + SX, 1,1-bis(4-chlorophenyl)ethanol (DMC) + SX, 1,1-bis(4-chlorophenyl)-2,2,2-trifluoroethanol (FDMC) + SX, 1,2-epoxy-1,2,3,4-tetrahydronaphthalene (ETN) + SX, 1,1,1-trichloro-2,3-expoxypropane (ETP) + SX, phenylsaligenin cyclic phosphate (PSCP) + SX, S,S,S-tributyl phosphorotrithioate (TBPT) + SX, and triphenyl phosphate (TPP) + SX SX.

[0040] Of the other insecticidal active compounds, repellents and synergists that may be further contained, preferred are one or more compounds selected from the group consisting of allethrin, bioallethrin, bioresmethrin, dimefluthrin, empenthrin, epsilonmetofluthrin, epsilonmofluorothrin, flumethrin, meperfluthrin, metofluthrin, mofluorothrin, prallethrin, profluthrin, resmethrin, tetramethrin, tetramethylfluthrin, transfluthrin, imiprothrin, heptafluthrin, Permethrin, fenothrin, cyphenothrin, cypermethrin, cyfluthrin, etofenprox, deltamethrin, fenpropathrin, furamethrin, pyrethrins, acetamiprid, clothianidin, dinotefuran, imidacloprid, thiamethoxam, thiacloprid, indoxacarb, brofuranilide, fenitrothion, cyphenothrin, sulfoxaflor, pyriproxyfen, piperonyl butoxide, and N-(2-ethylhexyl)-8,9,10-trinorborn-5-ene-2,3-dicarboximide.

[0041] Furthermore, to the aerosol formulation that can be used in the method of the present invention, buffers, fragrances, rust inhibitors, antifungal agents, pH adjusters, etc. can be added as needed within the scope of achieving the object of the present invention.

[0042] The spray amount of the pesticide aerosol used in the method of the present invention at 20°C varies depending on the spray amount per second and the spray time, with examples including, but not limited to, 0.5 to 10 seconds. Examples of spray amounts and spray times include 1 to 200 g / 5 seconds, preferably 1 to 50 g / 5 seconds, and more preferably 1 to 30 g / 5 seconds. A spray amount within the above range results in less wetting of the target surface with spray particles and excellent usability. The spray amount of the one-push aerosol at 20°C is not particularly limited, but examples include 0.01 to 0.5 g per push, preferably 0.05 to 0.3 g, and more preferably 0.1 to 0.2 g. Multiple one-push sprays may also be used. The spray amount can be adjusted by adjusting the specifications of the aerosol valve, the nozzle hole diameter of the spray button, the nozzle shape, the type of propellant, the content ratio of the concentrate to the propellant, and the internal pressure of the container. The internal pressure of the container is preferably 0.3 to 0.6 MPa. The particle size of the compound sprayed from the nozzle is not particularly limited, but examples thereof include a representative particle size (representative particle size: XR value calculated by the Rosin-Rammler distribution method) of 1 to 250 μm at 20°C and a spray distance of 30 cm, preferably 3 to 100 μm, and more preferably 5 to 50 μm. Specific examples include 1.5, 10, 14, 15, 30, 50, 100, and 200 μm. Similar ranges can be mentioned for one-push aerosols.

[0043] The control method of the present invention is carried out by spraying an effective amount of the present compound onto sanitary pests, places where sanitary pests can pass through, and / or places where sanitary pests can inhabit. Specifically, the control method is carried out by using an aerosol containing the present compound and spraying the compound onto sanitary pests, places where sanitary pests can pass through, and / or places where sanitary pests can inhabit. In the present invention, "control" includes extermination and prevention. In practice, it is desirable to spray an aerosol containing the present compound toward the space of the place to be controlled. The spray amount in this case is usually 0.001 to 1000 mg / m2, calculated as the amount of the present compound. ３ and preferably 0.001 to 100 mg / m ３and more preferably 0.01 to 10 mg / m ３ The aerosol containing the present compound can be sprayed in a room, a living room, a dining room, a closet, a storage closet, a Japanese-style chest of drawers or other cabinets, a cupboard, a toilet, a bathroom, a storeroom, a warehouse, the inside of a car, or in an open space outdoors.

[0044] The method of the present invention can also be used as a total spray aerosol formulation to enhance insecticidal activity and persistence and to provide an effective control method for sanitary pests that are resistant to insecticides.

[0045] In this specification, sanitary pests include arthropods and mollusks that are harmful to humans and livestock, as well as arthropods and mollusks that are disliked due to their unpleasant appearance or the tendency to infest (also referred to as nuisance pests). Specific examples include the following:

[0046] Order Blattodea: Family Ectobiidae such as German cockroach (Blattella germanica); Family Blattidae such as Smoky brown cockroach (Periplaneta fuliginosa), American cockroach (Periplaneta americana), American cockroach (Periplaneta australasiae), Brown brown cockroach (Periplaneta brunnea), Asian cockroach (Blatta orientalis), Turkestan cockroach (Blatta lateralis), and Brown banded cockroach (Supella longipalpa).

[0047] Order Siphonaptera: Family Pulicidae such as human flea (Pulex irritans), cat flea (Ctenocephalides felis), dog flea (Ctenocephalides canis), rat flea (Xenopsylla cheopis), chicken flea (Echidnophaga gallinacea), etc.; Family Hectopsyllidae such as sand flea (Tunga penetrans); and Family Ceratophyllidae such as European rat flea (Nosopsyllus fasciatus).

[0048] Psocodae: Trogiidae, such as Trogium pulsatorium; Liposcelidae or Liposcelididae, such as Liposcelis corrodens, Liposcelis bostrychophila, Liposcelis pearmani, and Liposcelis entomophila.

[0049] Thysanura: Family Lepismatidae, including the Japanese silverfish (Ctenolepisma villosa) and the European silverfish (Lepisma saccharina).

[0050] Acari: Haemaphysalis longicornis, Haemaphysalis flava, Haemaphysalis japonica, Haemaphysalis campanulata, Dermacentor variabilis, Dermacentor taiwanensis, Dermacentor andersoni, Dermacentor reticulatus, Ixodes ovatus, Ixodes persulcatus, Ixodes scapularis, Ixodes pacificus, Ixodes holocyclus, Ixodes ricinus, Amblyomma nigricans Ixodidae ticks such as Amblyomma americanum, Amblyomma maculatum, Rhipicephalus microplus, Rhipicephalus annulatus, Rhipicephalus sanguineus, Rhipicephalus appendiculatus, and Rhipicephalus decoloratus; Argasidae ticks such as Argas persicus, Ornithodoros hermsi, and Ornithodoros turicata; Acaridae ticks such as Tyrophagus putrescentiae and Tyrophagus similis; Dermatophagoides farinae and Dermatophagoides pteronyssinus. Pyroglyphidae, such as Pteronyssinus;Cheyletidae, such as Cheyletus eruditus, Cheyletus malaccensis, Chelacaropsis moorei, and Cheyletiella yasguri; Psoroptidae, such as Psoroptes ovis, Psoroptes equi, Knemidocoptes mutans, Otodectes cynotis, and Chorioptes spp.; Notoedres cati, Notoedres muris, and Sarcoptes Sarcoptidae such as Sarcoptes scabiei; Listrophoridae such as Listrophorus gibbus; Dermanyssidae such as Dermanyssus gallinae; Macronyssidae such as Ornithonyssus sylviarum and Ornithonyssus bacoti; Varroidae such as Varroa jacobsoni; Demodocidae such as Demodex canis and Demodex cati; Leptotrombidium akamushi and Leptotrombidium pallidum. Trombiculidae, such as Leptotrombidium scutellare, Leptotrombidium pallidum, and Leptotrombidium scutellare;

[0051] Hymenoptera: Solenopsis spp. such as the red fire ant (Solenopsis invicta), red fire ant (Solenopsis geminata), southern fire ant (Solenopsis xyloni), and black imported fire ant (Solenopsis richteri), leafcutter ants (Atta spp.) such as the brown leaf cutting ant (Atta capiguara), small leafcutter ants (Acromyrmex spp.), Paraponera clavata, Ochetellus glaber, house ant (Monomorium pharaonis), Argentine ant (Linepithema humile), Japanese mountain ant (Formica japonica), water-striped ant (Pristomyrmex punctutus), and Japanese house ant (Pheidole Camponotus spp., such as Camponotus noda, Pheidole megacephala, Camponotus japonicus, Camponotus obscuripes, Black carpenter ant (Camponotus pennsylvanicus), Florida carpenter ant (Camponotus floridanus), and Western carpenter ant (Camponotus modoc), harvester ants (Pogonomyrmex spp.), and fire ant species (Pogonomyrmex spp.), such as Pogonomyrmex occidentalis, Wasmania spp., such as Wasmania auropunctata, Crematogaster spp.Formicidae, such as the odorous house ant (Tapinoma sessile), pavement ant (Tetramorium caespitum), pyramid ant (Dorymyrmex insanus), European fire ant (Myrmica rubra), and red fire ant (Anoplolepis gracilipes); Vespidae, such as the giant hornet (Vespa mandarinia), hairy hornet (Vespa simillima), small hornet (Vespa analis), red hornet (Vespa velutina), and Japanese paper wasp (Polistes jokahamae); Siricidae, such as the fir wasp (Urocerus gigas); and Bethylidae.

[0052] Coleoptera: Curculionidae, such as Sitophilus zeamais, Sitophilus oryzae, and Sitophilus granarius; Tenebrionidae, such as Tribolium castaneum, Tribolium confusum, and Alphitobius diaperinus; Bostrychidae, such as Lyctus brunneus and Rhizopertha dominica; Ptinidae; Anoplophora Cerambycidae, such as Melanotus malasiaca, Migdolus fryanus, and Aromia bungii; Melanotus okinawensis, Agriotes fuscicollis, Melanotus legatus, Anchastus spp., Conoderus spp., Ctenicera spp., Limonius spp., and Aeolus spp.Elateridae (elateridae) such as the blue-leafed rove beetle (Paederus fuscipes); Staphylinidae (dermestidae) such as the small round dermestid beetle (Anthrenus verbasci), the white-spotted dermestid beetle (Dermestes maculates), and the small red dermestid beetle (Trogoderma granarium); Anobiidae (tobacco beetles) such as the cigarette beetle (Lasioderma serricorne) and the cigarette beetle (Stegobium paniceum); Laemophloeidae (small flathead beetles) such as the red short flathead beetle (Cryptolestes ferrugineus); Oryzaephilus Silvanidae, such as the slender-headed beetle Brassicogethes surinamensis, and Nitididae, such as the blossom beetle Brassicogethes aeneus.

[0053] Diptera: Drosophilidae such as Drosophila suzukii and Drosophila melanogaster; Phoridae such as Megaselia spiracularis; Psychodidae such as Clogmia albipunctata; Sciaridae such as Bradysia difformis; Culex pipiens pallens, Culex tritaeniorhynchus, Culex pipiens f. molestus, Culex quinquefasciatus, Culex quinquefasciatus, Culex pipiens f. molestus Culicidae, such as Aedes pipiens, Culex vishnui, Aedes albopictus, Aedes aegypti, Anopheles sinensis, Anopheles gambiae, Anopheles stephensi, Anopheles freeborni, Anopheles punctipennis, Anopheles quadrimaculatus, Anopheles coluzzii, Anopheles albimanus, Anopheles sundaicus, Anopheles arabiensis, Anopheles funestus, Anopheles darlingi, Anopheles farauti, and Anopheles minimus; yezoensis), the black fly (Simulium ornatum), and the black fly (Simulium spp.Simulidae such as Tabanus trigonus, black house fly (Tabanus atratus), striped house fly (Tabanus lineola), and deer fly (Chrysops sp.); Muscidae such as Musca domestica, Muscina stabulans, Stomoxys calcitrans, and Haematobia irritans; Calliphoridae such as Lucilia sp., Calliphora sp.; Sarcophagidae such as Sarcophaga sp., Wohlfahrtia sp.; Ceratopogonidae such as Leptoconops sp., Chironomus nigricans, and Chironomus nigricans. The Chironomidae family includes Chironomus plumosus, Chironomus yoshimatsui, and Glyptotendipes tokunagai; the Fannidae family includes Chironomus yoshimatsui, Chironomus plumosus, Chironomus yoshimatsui, and Glyptotendipes tokunagai.

[0054] Lepidoptera: Tineidae, such as Tinea translucens and Tineola bisselliella.

[0055] Hemiptera: Family Cimicidae such as Cimex lectularius and Cimex hemipterus; Family Cicadidae such as Quesada gigas; Family Reduviidae such as Triatoma infestans, Triatoma rubrofasciata, Triatoma dimidiata, Triatoma sanguisuga, Triatoma protracta, and Rhodonius prolixus.

[0056] Araneae: Eutichuridae, such as Cheiracanthium japonicum; Theridiidae, such as Latrodectus hasseltii. Polydesmida: Paradoxosomatidae, such as Oxidus gracilis and Nedyopus tambanus. Isopoda: Armadillidiidae, such as Armadillidium vulgare. Chilopoda: Scutigeridae such as Thereuonema hilgendorfi; Scolopendridae such as Scolopendra subspinipes; Ethopolyidae such as Bothropolys rugosus. Class Gastropoda: Family Limacidae such as the brown slug (Limax marginatus) and the yellow slug (Limax flavus); Family Philomycidae such as the slug (Meghimatium bilineatum); Family Ampullariidae such as the apple snail (Pomacea canaliculata); Family Lymnaeidae such as the lymnae snail (Austropeplea ollula).

[0057] The present invention will be explained in more detail below with reference to examples such as formulation examples and test examples, but the present invention is not limited to these examples.

[0058] First, formulation examples will be described.

[0059] Formulation Example 1: 4.3 parts of SX and 10.0 parts of isopropyl myristate were placed in an aerosol container, a valve was attached to the aerosol container, and a propellant (liquefied petroleum gas (propane / butane mixture, gas pressure 4.8 kg / cm)) was poured through the valve.２ An actuator was attached to the container to obtain an oily aerosol containing the present compound.

[0060] Formulation Example 2: 0.1 parts of SX, 9.0 parts of Solvesso 200ND, and 20.9 parts of Neothiosol were placed in an aerosol container (Toyo Seikan, WE290WO), a valve was attached to the aerosol container, and a propellant (liquefied petroleum gas (propane / butane mixture, gas pressure 3.5 kg / cm)) was poured through the valve. ２ The container was filled with 70 parts of a 1:1 mixture (by weight of dimethyl ether and ethanol) (20°C) and dimethyl ether, and an actuator was attached to obtain an oily aerosol containing the present compound.

[0061] Formulation Example 3: An aqueous solution obtained by dissolving 0.1 parts of SX in 60 parts of deionized water was placed in an aerosol container. A solution obtained by dissolving 1 part of sorbitan monooleate (trade name: Rheodol SP-010, Kao Corporation) in 18.9 parts of Neothiosol (a saturated hydrocarbon solvent, Chuo Kasei Co., Ltd.) was added to the aerosol container, and a valve was attached to the aerosol container. A propellant (liquefied petroleum gas (propane / butane mixture, gas pressure 3.5 kg / cm)) was poured into the aerosol container through the valve. ２ 20 parts of a 100% aqueous solution of the present compound (20 parts of ethanol, 20°C) was filled into the container, and an actuator was attached to the container to obtain an aqueous aerosol containing the present compound.

[0062] Formulation Example 4 0.2 parts of SX and 10.0 parts of absolute ethanol were placed in an aerosol container, a valve was attached, 89.8 parts of dimethyl ether was added through the valve, and an actuator was attached to prepare a total-amount spray aerosol.

[0063] Formulation Example 5 0.1 parts of SX was placed in a pressure-resistant container in advance, and after a pressure valve was attached to the pressure-resistant container, 99.9 parts of a propellant (liquefied carbon dioxide gas) was injected from the nozzle side to obtain an aerosol.

[0064] Next, the excellent control effect of the method of the present invention will be demonstrated by test examples. Compound A, Compound B, and Comparative Compounds 1 to 4 are compounds listed in Table 2. Comparative Compounds 1 and 2 are compounds listed in Patent Document 4, and Comparative Compounds 3 and 4 are compounds listed in Patent Document 3.

[0065]

[0066] Aerosol preparations containing the compounds shown in Table 2 were prepared according to the method described in Formulation Example 2. The internal pressure of the container of the prepared aerosol preparation at 20°C was 0.5 MPa, the spray amount was 3 g / 5 seconds, and the typical particle size (XR value) was 14 to 15 μm.

[0067] Test Example 1: Ten adult German cockroaches (five males and five females) were released into a plastic container (diameter: 12.4 cm, height: 10.2 cm), and placed in the center of the bottom of a cylindrical chamber with a diameter of 17.2 cm. An aerosol containing a compound shown in Table 2, prepared according to the method described in Formulation Example 2, was sprayed from a height of 50 cm for 1.35 seconds with an amount of approximately 800 mg sprayed. One day after spraying, the number of dead and distressed individuals was counted, and the percentage of distressed individuals was calculated using the following formula 1. Dead individuals refer to individuals that have completely stopped moving, and distressed individuals refer to individuals that cannot get up when placed on their backs. The results are shown in Table 3. (Formula 1): Percentage of distressed individuals (%) = {(number of dead individuals + number of distressed individuals) / number of individuals tested} x 100

[0068]

[0069] Test Example 2: Ten Argentine ant workers were released into a plastic cup (diameter: 10 cm, height: 4.5 cm) lined with filter paper (diameter: 8.2 cm). The cup was placed at the center of the bottom of a cylindrical chamber with a diameter of 17.2 cm. An aerosol containing a compound listed in Table 2, prepared according to the method described in Formulation Example 2, was sprayed from a height of 60 cm for a spray time of 0.34 or 0.68 seconds and an amount of approximately 400 mg or 200 mg. Seven days after spraying, the number of dead and agonizing individuals was counted, and the agonizing insect rate (%) was calculated using the following formula 2. Dead individuals refer to individuals that have completely stopped moving, and agonizing individuals refer to individuals that cannot get up when placed on their backs. The results are shown in Table 4. (Formula 2): agonizing insect rate (%) = {(number of dead individuals + number of agonizing individuals) / number of test individuals} x 100

[0070] From this, it was found that the present compounds A and B have a superior control effect against sanitary pests to the comparative compounds 1 to 4.

[0071] The method using the aerosol formulation of the present invention is free from the risk of contamination to the surroundings, has excellent efficacy, and is suitable for controlling sanitary pests.

Claims

1. Formula (I): 【Chemistry 1】 [In the formula, R 1 represents a C1-C3 haloalkoxy group, a C1-C3 haloalkylthio group, a C1-C3 haloalkylsulfinyl group, or a C1-C3 haloalkylsulfonyl group, and R 2 represents a hydrogen atom or a cyano group. A method for controlling sanitary pests, comprising applying an aerosol agent containing at least one compound selected from the group consisting of compounds represented by the following formula (I), an N-oxide thereof, and a salt thereof, and a propellant to sanitary pests, a place through which sanitary pests may pass, or a place where sanitary pests may inhabit.

2. The aerosol agent has the formula (I), 1 is a trifluoromethylsulfinyl group or a trifluoromethylsulfonyl group, and R 2 The sanitary pest control method according to claim 1, which is an aerosol agent containing a compound in which is a hydrogen atom.

3. The sanitary pest control method according to claim 1, wherein the aerosol agent contains a liquefied gas as a propellant.

4. The sanitary pest control method according to claim 1, wherein the aerosol agent further contains a hydrocarbon solvent.

5. The sanitary pest control method according to claim 1, wherein the aerosol agent further contains water.

6. The sanitary pest control method according to claim 1, wherein the aerosol agent further contains at least one insecticidal active ingredient.

7. The at least one insecticidal active ingredient is allethrin, bioallethrin, bioresmethrin, dimefluthrin, empenthrin, epsilonmetofluthrin, epsilonmonfluorothrin, flumethrin, meperfluthrin, metofluthrin, monfluorothrin, prallethrin, profluthrin, resmethrin, tetramethrin, tetramethylfluthrin, transfluthrin, imiprothrin, heptafluthrin, permethrin, fenothrin, cyphenothrin, cypermethrin, cyfluthrin, etofenprothrin, At least one selected from the group consisting of acetophenone, deltamethrin, fenpropathrin, furamethrin, pyrethrin, acetamiprid, clothianidin, dinotefuran, imidacloprid, thiamethoxam, thiacloprid, indoxacarb, brofuranilide, fenitrothion, cyphenothrin, sulfoxaflor, pyriproxyfen, piperonyl butoxide, and N-(2-ethylhexyl)-8,9,10-trinorborn-5-ene-2,3-dicarboximide. The sanitary pest control method according to claim 6, wherein the pest control agent is at least one selected from the group consisting of acetophenone, deltamethrin, fenpropathrin, furamethrin, pyreth ...

8. The sanitary pest control method according to any one of claims 1 to 7, wherein the sanitary pest is at least one kind of sanitary pest selected from the group consisting of Blattella, Hymenoptera, Diptera, Siphonaptera, Acarina, Lepidoptera and Coleoptera.

9. The aerosol according to any one of claims 1 to 7.

10. 10. The aerosol of claim 9, wherein the aerosol comprises liquefied petroleum gas as a propellant.

11. The aerosol according to claim 10, wherein the aerosol comprises 0.01 to 5 parts by weight of the compound of formula (I), 30 to 90 parts by weight of liquefied petroleum gas, and 20 to 70 parts by weight of a hydrocarbon solvent, per weight of the aerosol.

12. 10. The aerosol formulation according to claim 9, which is packed in a pressure-resistant container.

13. 10. An aerosol product comprising the aerosol agent according to claim 9 packed in a pressure-resistant container.

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