3,4-dihydroquinolin-2(1H)-one compound

JPWO2024005113A5Pending Publication Date: 2026-06-30
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Patent Information

Authority / Receiving Office
JP · JP
Patent Type
Applications
Filing Date
2023-06-29
Publication Date
2026-06-30

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Abstract

The present invention addresses the problem of providing a novel compound that has a thyroid-stimulating hormone receptor antagonist activity and is useful for the treatment of thyroid-related diseases.　The present invention relates to a 3,4-dihydroquinolin-2(1H)-one compound represented by formula (I) or a pharmacologically acceptable salt thereof. The compound according to the present invention or a pharmacologically acceptable salt thereof has an antagonist activity against thyroid-stimulating hormone receptors and is therefore useful as a therapeutic agent for thyroid-related diseases (e.g., hyperthyroidism, Graves' disease, thyroid eye disease and thyroid cancer) and others.
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