Health functional food composition containing complex dietary fiber and method for preparing the same

Abstract

The present invention relates to a health functional food composition containing complex dietary fiber and a method for manufacturing the same. A health functional food composition containing complex dietary fiber according to one embodiment of the present invention comprises 1 part by weight of vitamin B6 hydrochloride, 0.5 parts by weight of beta-carotene, 3.5 parts by weight of a powdered vitamin E mixed preparation, 0.5 parts by weight of folic acid, 0.7 parts by weight of a vitamin A mixed preparation, 5 parts by weight of ginger concentrate powder, 4 parts by weight of broccoli concentrate powder, 2 parts by weight of carrot juice powder, 30.5 parts by weight of cabbage extract powder, 16.5 parts by weight of banana extract powder, 4.85 parts by weight of asparagus extract powder, 20.7 parts by weight of crystalline cellulose, 4 parts by weight of bamboo extract powder, 1.25 parts by weight of magnesium stearate, and 5 parts by weight of indigestible maltodextrin.

Description

Technology Field

[0001] The present invention relates to a health functional food composition containing complex dietary fiber and a method for manufacturing the same. Background Technology

[0002] In modern society, interest in the importance of dietary fiber intake is continuously increasing due to the Westernization of dietary habits and the increased consumption of processed foods. Dietary fiber is known to be involved in maintaining intestinal moisture, promoting intestinal peristalsis, and regulating the intestinal microbial environment; due to these functional characteristics, it is recognized as an important nutrient for managing intestinal health and maintaining metabolic health. Accordingly, various forms of health functional foods and dietary fiber supplements have been developed and are being used to supplement dietary fiber.

[0003] However, simply increasing the intake of dietary fiber does not always produce desirable effects. In general, it is known that excessive intake of dietary fiber can lead to side effects such as bloating, increased gas production, abdominal pain, or intestinal dysfunction. In particular, the likelihood of these side effects may increase if a large amount of a single type of dietary fiber is consumed or if the balance between soluble and insoluble dietary fiber is not properly maintained.

[0004] Dietary fiber is generally classified into soluble and insoluble dietary fiber, each exhibiting different physiological characteristics. Soluble dietary fiber dissolves in water and forms viscosity, thereby creating an intestinal fermentation environment and potentially influencing the activity of intestinal microorganisms, whereas insoluble dietary fiber absorbs water and expands, thereby promoting intestinal peristalsis and potentially influencing bowel movements. Due to these characteristics, it is reported that the effects of dietary fiber intake can be influenced not only by the total intake but also by the relative composition ratio of soluble and insoluble dietary fiber.

[0005] Recently, research results have also been reported indicating that the physiological effects of dietary fiber may vary depending on the dietary or constitutional characteristics of a population group. In particular, considering the dietary patterns and intestinal environmental characteristics of Asians, it has been suggested that maintaining the intake ratio of soluble to insoluble dietary fiber within a specific range may be more appropriate for managing intestinal health. From this perspective, there is growing interest in compositional technologies that include different types of dietary fiber in appropriate proportions, rather than products that simply increase dietary fiber content.

[0006] Meanwhile, conventional dietary fiber supplements have often been manufactured by primarily consisting of a single dietary fiber ingredient or simply mixing multiple dietary fiber ingredients, and products that achieve functional balance by considering the type and composition ratio of dietary fiber while including various plant-derived ingredients and nutritional components have been proposed only in limited numbers. Furthermore, even in the case of compositions that include vegetable or fruit-derived ingredients and vitamin components along with dietary fiber, there are not many instances where the composition ratio of each component is systematically designed to consider functional effects such as improving the intestinal environment.

[0007] Therefore, there is a need to develop a health functional food composition that can prevent side effects caused by excessive dietary fiber intake while ensuring the effect of improving the intestinal environment. Prior art literature

[0008] Republic of Korea Registered Patent Publication No. 10-1275523 The problem to be solved

[0009] The objective of the present invention is to provide a health functional food composition containing complex dietary fiber and a method for manufacturing the same, which can contribute to improving the intestinal environment while minimizing side effects such as abdominal distension, gas production, and intestinal function imbalance caused by excessive intake of a single dietary fiber component, by combining water-soluble dietary fiber and insoluble dietary fiber in a specific compositional ratio and including various fruit and vegetable extract powders and vitamin-based compounds. means of solving the problem

[0010] The above objective is achieved, according to the present invention, by a health functional food composition containing complex dietary fiber comprising 1 part by weight of vitamin B6 hydrochloride, 0.5 parts by weight of beta-carotene, 3.5 parts by weight of a mixed preparation of vitamin E powder, 0.5 parts by weight of folic acid, 0.7 parts by weight of a mixed preparation of vitamin A, 5 parts by weight of ginger concentrate powder, 4 parts by weight of broccoli concentrate powder, 2 parts by weight of carrot juice powder, 30.5 parts by weight of cabbage extract powder, 16.5 parts by weight of banana extract powder, 4.85 parts by weight of asparagus extract powder, 20.7 parts by weight of crystalline cellulose, 4 parts by weight of bamboo extract powder, 1.25 parts by weight of magnesium stearate, and 5 parts by weight of indigestible maltodextrin.

[0011] delete

[0012] In addition, the weight ratio of water-soluble dietary fiber to insoluble dietary fiber contained in the above composition is 1:2.

[0013] In addition, the above beta-carotene is a beta-carotene-containing preparation with a beta-carotene content of 10 wt%, the above ginger concentrate powder is a concentrate powder with a ginger-derived active ingredient content of 20 wt%, the above cabbage extract powder is an extract powder with a cabbage-derived active ingredient content of 2 wt%, and the above asparagus extract powder is an extract powder with an asparagus-derived active ingredient content of 1 wt%.

[0014] In addition, a method for preparing a health functional food composition containing complex dietary fiber according to one embodiment of the present invention comprises: a mixing step of mixing 1 part by weight of vitamin B6 hydrochloride, 0.5 parts by weight of beta-carotene, 3.5 parts by weight of powdered vitamin E mixed preparation, 0.5 parts by weight of folic acid, 0.7 parts by weight of vitamin A mixed preparation, 5 parts by weight of ginger concentrate powder, 4 parts by weight of broccoli concentrate powder, 2 parts by weight of carrot juice powder, 30.5 parts by weight of cabbage extract powder, 16.5 parts by weight of banana extract powder, 4.85 parts by weight of asparagus extract powder, 20.7 parts by weight of crystalline cellulose, 4 parts by weight of bamboo extract powder, 1.25 parts by weight of magnesium stearate, and 5 parts by weight of indigestible maltodextrin to produce a mixture; and a filtration step of passing the mixture through a filter screen with a mesh size of 1.2 mm or less to produce a filtered mixture. It includes a moisture adjustment step of adjusting the moisture activity of the above-mentioned filter mixture to 0.6 AW or less; and a tableting step of producing tablets by compressing the above-mentioned filter mixture with adjusted moisture activity into a dose of 500 mg ± 4% per tablet. Effects of the invention

[0015] According to the present invention, by adopting a composite dietary fiber structure in which water-soluble dietary fiber and insoluble dietary fiber are combined in a specific weight ratio, a health functional food composition can be provided that can contribute to improving the intestinal environment while mitigating side effects that may occur when consuming excessive dietary fiber.

[0016] In addition, by adjusting the weight ratio of soluble dietary fiber to insoluble dietary fiber to a specific range, the intestinal moisture retention characteristics and the function of promoting intestinal peristalsis can be expressed in a balanced manner, thereby providing a beneficial effect for intestinal health management.

[0017] In addition, through the design of a composition containing various plant-derived extract powders along with complex dietary fiber, the intestinal environment-improving function of dietary fiber and the nutritional function of plant-derived bioactive components can be expressed complementarily.

[0018] In addition, by including vitamin-based compounds, it is possible to realize a health functional food composition capable of providing a balanced combination of nutritional components along with the functional effects of dietary fiber and plant-derived extract powder.

[0019] Meanwhile, the effects of the present invention are not limited to those mentioned above, and various effects may be included within the scope obvious to a person skilled in the art from the contents described below. Brief explanation of the drawing

[0020] FIG. 1 is a block diagram illustrating a method for preparing a health functional food composition containing complex dietary fiber according to one embodiment of the present invention, and FIG. 2 is a graph showing the results of evaluating the effects of a health functional food composition containing complex dietary fiber according to one embodiment of the present invention on promoting intestinal peristalsis and inhibiting intestinal gas production. FIG. 3 is a graph showing the results of evaluating the intestinal pH and mucosal protective effects of a health functional food composition containing complex dietary fiber according to one embodiment of the present invention, and FIG. 4 is a graph showing the results of measuring the gastric emptying rate of a health functional food composition containing complex dietary fiber according to one embodiment of the present invention, and FIG. 5 is a graph showing the results of measuring post-meal blood triglyceride content of a health functional food composition containing complex dietary fiber according to one embodiment of the present invention after a high-fat diet, and Figure 6 is a graph showing the results of measuring the increase in blood triglycerides after a high-fat diet of a health functional food composition containing complex dietary fiber according to one embodiment of the present invention. Specific details for implementing the invention

[0021] Hereinafter, some embodiments of the present invention will be described in detail with reference to exemplary drawings. It should be noted that in assigning reference numerals to the components of each drawing, the same components are given the same reference numeral whenever possible, even if they are shown in different drawings.

[0022] Furthermore, in describing embodiments of the present invention, if it is determined that a detailed description of related known configurations or functions would hinder understanding of the embodiments of the present invention, such detailed description is omitted.

[0023] In addition, terms such as first, second, A, B, (a), (b), etc. may be used when describing the components of the embodiments of the present invention. These terms are used merely to distinguish the components from other components, and the essence, order, or sequence of the components is not limited by the terms.

[0024] In this specification, "improvement of the intestinal environment" means (a) inhibiting the progression of intestinal imbalance caused by reduced intestinal moisture retention and reduced intestinal peristalsis in an individual, (b) alleviating symptoms related to reduced intestinal function such as abdominal distension, digestive discomfort and irregular bowel movements, or (c) normalizing the intestinal microbial environment.

[0026] Hereinafter, a health functional food composition containing complex dietary fiber according to one embodiment of the present invention will be described in detail.

[0027] A health functional food composition containing complex dietary fiber according to one embodiment of the present invention comprises vitamin B6 hydrochloride, beta-carotene, powdered vitamin E mixed preparation, folic acid, vitamin A mixed preparation, ginger concentrate powder, broccoli concentrate powder, carrot juice powder, cabbage extract powder, banana extract powder, asparagus extract powder, crystalline cellulose, bamboo extract powder, magnesium stearate, and indigestible maltodextrin.

[0028] Pyridoxine hydrochloride, the hydrochloride form of the water-soluble vitamin B6, can act as a coenzyme involved in amino acid metabolism and neurotransmitter synthesis in the body. Vitamin B6 contributes to maintaining vascular health by promoting the breakdown of homocysteine ​​produced during protein metabolism, and may be involved in regulating intestinal immune function and protecting the mucous membranes.

[0029] In the present invention, vitamin B6 hydrochloride can contribute to improving the intestinal environment and maintaining overall nutritional balance together with a complex dietary fiber composition.

[0030] Beta-carotene is a carotenoid pigment abundantly found in plants such as carrots and sweet potatoes, and it can act as a provitamin A that is converted into vitamin A in the body as needed. Through its powerful antioxidant activity, beta-carotene alleviates oxidative stress in the intestines and can perform a protective function of the intestinal mucosa by contributing to the differentiation and maintenance of epithelial cells.

[0031] The beta-carotene used in the present invention is a beta-carotene-containing preparation in which natural or synthetic beta-carotene is dispersed in a carrier and powdered. Since beta-carotene is a component sensitive to oxidation, if the beta-carotene content in the preparation exceeds 10 wt%, oxidative decomposition proceeds rapidly during the manufacturing process, which may result in loss of the active ingredient; if it is less than 10 wt%, it is difficult to supply sufficient beta-carotene within the target formulation amount, which may lead to a decrease in antioxidant and intestinal mucosal protective effects.

[0032] Therefore, in order to simultaneously secure the oxidative stability of beta-carotene and achieve functional effects, the present invention uses a beta-carotene-containing preparation having a beta-carotene content of 10 wt%.

[0033] In addition, the composition of the present invention contains natural beta-carotene in the carrot juice powder, but additionally includes a beta-carotene-containing preparation to meet the target content.

[0034] Powdered Vitamin E mixture (Tocopherol mixture) is a mixed preparation containing alpha-, beta-, gamma-, and delta-tocopherol, which is powdered natural tocopherol extracted and purified from vegetable oils.

[0035] Powdered vitamin E mixed preparations function as fat-soluble antioxidant vitamins that inhibit oxidative damage to cell membranes, contribute to inhibiting lipid peroxidation in the intestines and activating immune cells, and may also be involved in regulating the intestinal microbial environment.

[0036] Folic acid is a component belonging to the water-soluble B vitamin group and is produced through chemical synthesis or fermentation processes.

[0037] Folic acid can act as an essential coenzyme for DNA synthesis and cell division, and can contribute to maintaining intestinal mucosal function by participating in the normal proliferation and regeneration of intestinal mucosal epithelial cells. In addition, it can contribute to regulating intestinal inflammatory responses by participating in homocysteine ​​metabolism.

[0038] A vitamin A mixture is a mixed preparation containing retinol and derivatives such as retinyl acetate and retinyl palmitate, which is powdered by dispersing them on a carrier.

[0039] Vitamin A combination preparations play an essential role in the differentiation and maintenance of intestinal mucosal epithelial cells and can perform an intestinal mucosal protective function by promoting the secretion of secreted IgA (sIgA), an intestinal immune cell, and strengthening mucosal immune function.

[0040] Ginger concentrated powder is a raw material manufactured by washing and drying the rhizomes of *Zingiber officinale*, concentrating the extract through a hot water extraction process, and then powdering it using a spray drying method.

[0041] Ginger concentrate powder contains bioactive components such as gingerol, shogaol, and zingerone, which promote the movement of gastrointestinal smooth muscles and aid in the expulsion of intestinal gas, and can contribute to improving the intestinal environment through anti-inflammatory and antioxidant effects.

[0042] The ginger concentrate powder used in the present invention is a concentrate powder having a ginger-derived active ingredient content of 20 wt%. If the active ingredient content is less than 20 wt%, it is difficult to sufficiently supply functional components such as gingerol and shogaol within the target formulation amount, which may lead to a decrease in gastrointestinal motility promotion and anti-inflammatory effects. If it exceeds 20 wt%, the palatability of the product may be reduced due to the strong spicy taste and irritancy characteristic of ginger. Therefore, in order to simultaneously secure functional effects and palatability, the present invention uses ginger concentrate powder having a ginger-derived active ingredient content of 20 wt%.

[0043] Broccoli concentrated powder is a raw material produced by washing and crushing broccoli (Brassica oleracea var. italica), followed by hot water extraction and concentration processes, and then pulverizing it using a spray drying method.

[0044] Broccoli concentrate powder contains soluble and insoluble dietary fiber along with bioactive components such as sulforaphane and indole-3-carbinol. Sulforaphane protects the intestinal mucosa through antioxidant and anti-inflammatory actions, and the dietary fiber components can promote the growth of beneficial bacteria by acting as a fermentation substrate for intestinal microorganisms.

[0045] Carrot juice powder is a raw material manufactured by washing and juicing carrots (Daucus carota) and then pulverizing the juice using a spray-drying method.

[0046] Carrot juice powder contains carotenoid components such as beta-carotene and lutein, as well as dietary fiber. Carrot-derived dietary fiber has excellent water retention capacity in the intestines, which can contribute to increasing stool volume and shortening intestinal transit time. Carotenoid components play a role in alleviating oxidative damage to the intestinal mucosa, and in the present invention, they may be included together with a beta-carotene-containing preparation to supplement the target content of beta-carotene.

[0047] Cabbage extract powder is a raw material prepared by washing and crushing cabbage (Brassica oleracea var. capitata), concentrating the extract through a hot water extraction process, and then pulverizing it using a spray-drying method.

[0048] Cabbage extract powder is rich in vitamin U (S-methylmethionine), sulforaphane, and dietary fiber, and vitamin U can repair damage to the gastric and intestinal mucosa and strengthen mucosal protective functions.

[0049] The cabbage extract powder used in the present invention is an extract powder having an active ingredient content of 2 wt% derived from cabbage. If the active ingredient content is less than 2 wt%, it is difficult to supply sufficient functional ingredients within the target formulation amount, which may reduce the protective effect on the intestinal mucosa; if it exceeds 2 wt%, the characteristic off-flavor and bitter taste of cabbage become strong, which may degrade the sensory quality of the product. Therefore, in the present invention, cabbage extract powder with an active ingredient content of 2 wt% is used to simultaneously secure functional effects and sensory quality.

[0050] Banana extract powder is a raw material manufactured by washing and crushing bananas (*Musa paradisiaca*), followed by hot water extraction and concentration processes, and then pulverizing them using a spray-drying method.

[0051] Banana extract powder is rich in water-soluble dietary fibers such as fructooligosaccharide and pectin, as well as resistant starch, and these components act as prebiotics that promote the growth of beneficial intestinal bacteria such as Bifidobacterium, thereby contributing to the improvement of the intestinal microbial environment.

[0052] Asparagus extract powder is a raw material manufactured by washing and crushing Asparagus officinalis, concentrating the extract through a hot water extraction process, and then pulverizing it using a spray-drying method.

[0053] Asparagus extract powder contains bioactive components such as inulin and saponin, as well as water-soluble dietary fiber. Inulin is a representative prebiotic component that can contribute to maintaining the balance of intestinal microorganisms by promoting the proliferation of beneficial bacteria and inhibiting the growth of harmful bacteria.

[0054] The asparagus extract powder used in the present invention is an extract powder having an active ingredient content of 1 wt% derived from asparagus. If the active ingredient content is less than 1 wt%, active ingredients such as inulin, which contribute to regulating the intestinal microbial environment, may not be sufficiently supplied; if it exceeds 1 wt%, the palatability of the product may be reduced due to the strong flavor characteristic of asparagus. Therefore, in the present invention, asparagus extract powder with an active ingredient content of 1 wt% is used to simultaneously secure functional effects and palatability.

[0055] Microcrystalline cellulose is an insoluble dietary fiber produced by acid hydrolyzing plant-derived cellulose to remove the amorphous regions and purifying and drying only the crystalline regions.

[0056] Crystalline cellulose does not dissolve in water and functions to facilitate bowel movements by increasing the volume of stool and promoting intestinal peristalsis through its expansion by absorbing moisture in the intestines.

[0057] In the present invention, crystalline cellulose serves as a major source of insoluble dietary fiber, and while it functions to promote intestinal peristalsis, it also acts as a binder in the tablet compression process, thereby contributing to securing the hardness and disintegration properties of the tablet.

[0058] Bamboo extract powder is a raw material manufactured by washing and drying the stems or leaves of bamboo (Phyllostachys sp.), concentrating the extract through a hot water extraction process, and then pulverizing it using a spray-drying method.

[0059] Bamboo extract powder contains insoluble dietary fiber as a main component, and bamboo-derived insoluble dietary fiber can contribute to promoting the adsorption and excretion of harmful substances in the intestines and shortening intestinal transit time.

[0060] In addition, bamboo extract powder contains flavonoid compounds, which are antioxidant components, and can also contribute to protecting the intestinal mucosa. In the present invention, bamboo extract powder is included as a source of insoluble dietary fiber along with crystalline cellulose.

[0061] Magnesium stearate is a magnesium salt of stearic acid, a plant fatty acid, and is produced by separating stearic acid from plant oils such as palm oil or sunflower oil and reacting it with magnesium.

[0062] Magnesium stearate can be used as a lubricant to improve the fluidity of powder raw materials and prevent the raw materials from adhering to the surface of the tablet press during tableting, and in the present invention, it can be included as an excipient to ensure the tableting process efficiency and / or formulation stability of the composition.

[0063] Indigestible maltodextrin is a water-soluble dietary fiber produced by heating corn starch, etc., under high temperature and acid conditions to rearrange some of the α-1,4 bonds of the starch into α-1,6 bonds and β bonds, followed by enzymatic treatment and purification processes.

[0064] Indigestible maltodextrin can reach the large intestine without being broken down by digestive enzymes and act as a fermentation substrate for beneficial intestinal bacteria, and by dissolving in water to form a viscous gel, it can maintain moisture in the intestines and contribute to alleviating the rise in blood sugar after meals.

[0065] In the present invention, indigestible maltodextrin can serve as a major source of water-soluble dietary fiber and can function to create an intestinal fermentation environment, and can form a complex dietary fiber structure together with insoluble dietary fiber such as crystalline cellulose and / or bamboo extract powder.

[0067] In addition, a health functional food composition containing complex dietary fiber according to one embodiment of the present invention comprises 1 part by weight of vitamin B6 hydrochloride, 0.5 parts by weight of beta-carotene, 3.5 parts by weight of powdered vitamin E mixed preparation, 0.5 parts by weight of folic acid, 0.7 parts by weight of vitamin A mixed preparation, 5 parts by weight of ginger concentrate powder, 4 parts by weight of broccoli concentrate powder, 2 parts by weight of carrot juice powder, 30.5 parts by weight of cabbage extract powder, 16.5 parts by weight of banana extract powder, 4.85 parts by weight of asparagus extract powder, 20.7 parts by weight of crystalline cellulose, 4 parts by weight of bamboo extract powder, 1.25 parts by weight of magnesium stearate, and 5 parts by weight of indigestible maltodextrin.

[0068] In the composition of the present invention, if the content of vitamin B6 hydrochloride is less than 1 part by weight, it may be difficult to supply sufficient vitamin B6 necessary for regulating intestinal immune function and protecting the mucous membrane, and if it exceeds 1 part by weight, the balance of combination with other vitamin components such as folic acid may be reduced, and nutritional imbalance may occur.

[0069] In the composition of the present invention, if the content of beta-carotene is less than 0.5 parts by weight, it may be difficult to sufficiently express the intestinal mucosal protection and antioxidant effects, and if it exceeds 0.5 parts by weight, the combined content of natural beta-carotene and vitamin A mixed preparation contained in carrot juice powder becomes excessive, which may lead to an excessive intake of vitamin A.

[0070] In the composition of the present invention, if the content of the powdered vitamin E mixed preparation is less than 3.5 parts by weight, it may be difficult to sufficiently express the effects of inhibiting lipid peroxidation in the intestines and protecting the cell membrane, and if it exceeds 3.5 parts by weight, there may be concerns about excess due to accumulation in the body due to the characteristics of fat-soluble vitamins.

[0071] In the composition of the present invention, if the content of folic acid is less than 0.5 parts by weight, it may be difficult to supply sufficient folic acid necessary for the normal proliferation and regeneration of intestinal mucosal epithelial cells, and if it exceeds 0.5 parts by weight, the balance of combination with vitamin B6 hydrochloride may be reduced, and the effect of regulating homocysteine ​​metabolism may be reduced.

[0072] In the composition of the present invention, if the content of the vitamin A mixed preparation is less than 0.7 parts by weight, it may be difficult to supply sufficient vitamin A necessary for the differentiation of intestinal mucosal epithelial cells and the strengthening of mucosal immune function, and if it exceeds 0.7 parts by weight, the combined content with provitamin A supplied from beta-carotene and carrot juice powder becomes excessive, which may lead to concerns about vitamin A overdose.

[0073] In the composition of the present invention, if the content of ginger concentrate powder is less than 5 parts by weight, it is difficult to sufficiently supply functional ingredients such as gingerol and shogaol, which may reduce the gastrointestinal motility promotion and anti-inflammatory effects, and if it exceeds 5 parts by weight, the palatability of the product may be reduced due to the strong spicy taste and irritancy characteristic of ginger.

[0075] In addition, a health functional food composition containing complex dietary fiber according to one embodiment of the present invention may include water-soluble dietary fiber and insoluble dietary fiber in a weight ratio of 1:2.

[0076] A health functional food composition containing complex dietary fiber according to one embodiment of the present invention may include indigestible maltodextrin, banana extract powder, and asparagus extract powder as components containing water-soluble dietary fiber, and may include crystalline cellulose, bamboo extract powder, broccoli concentrate powder, carrot juice powder, cabbage extract powder, and asparagus extract powder as components containing insoluble dietary fiber.

[0077] That is, a health functional food composition containing complex dietary fiber according to one embodiment of the present invention may include a ratio of the sum of the weights of the components containing water-soluble dietary fiber to the sum of the weights of the components containing insoluble dietary fiber in a ratio of 1:2.

[0078] A health functional food composition containing complex dietary fiber according to one embodiment of the present invention may include asparagus extract powder in an amount of 4.85 parts by weight.

[0079] Asparagus extract powder may contain soluble dietary fiber including inulin and / or fructooligosaccharide and insoluble dietary fiber including cellulose and / or hemicellulose, and may contain soluble dietary fiber and insoluble dietary fiber in a 1:1 ratio.

[0080] In the composition of the present invention, the dietary fiber content included in the asparagus extract powder corresponds to 12% of the total dietary fiber content of the composition, of which soluble dietary fiber may be included as 6% and insoluble dietary fiber as 6%.

[0081] The inulin component derived from asparagus extract powder acts as a prebiotic that promotes the growth of beneficial bacteria, such as Bifidobacterium, in the intestines, thereby contributing to the maintenance of intestinal microbial balance, and the insoluble dietary fiber component promotes intestinal peristalsis, facilitating bowel movements.

[0082] If the content of asparagus extract powder is less than 4.85 parts by weight, it is difficult to provide sufficient prebiotic components such as inulin, which may reduce the effect of maintaining the balance of intestinal microorganisms, and if it exceeds 4.85 parts by weight, the palatability of the product may decrease due to the strong flavor characteristic of asparagus.

[0083] In addition, a health functional food composition containing complex dietary fiber according to one embodiment of the present invention may include banana extract powder in an amount of 16.5 parts by weight.

[0084] Banana extract powder may contain water-soluble dietary fiber including pectin, fructooligosaccharide, and / or resistant starch.

[0085] The dietary fiber content of the banana extract powder in the composition of the present invention corresponds to 7% of the total dietary fiber content of the composition, and the entire amount may be included as water-soluble dietary fiber.

[0086] Water-soluble dietary fiber components derived from banana extract powder can act as fermentation substrates for beneficial intestinal bacteria and contribute to improving the intestinal microbial environment, while resistant starch components reach the large intestine without being broken down by digestive enzymes and can contribute to creating an intestinal fermentation environment.

[0087] If the content of banana extract powder is less than 16.5 parts by weight, it is difficult to provide sufficient prebiotic components such as fructooligosaccharides and pectin, which may reduce the effect of promoting the growth of beneficial bacteria in the intestines, and if it exceeds 16.5 parts by weight, it may have a negative effect on blood sugar levels after meals due to the excessive supply of banana-derived sugar components.

[0088] In addition, a health functional food composition containing complex dietary fiber according to one embodiment of the present invention may include indigestible maltodextrin in an amount of 5 parts by weight.

[0089] Indigestible maltodextrin is a water-soluble dietary fiber raw material, and the dietary fiber content of indigestible maltodextrin in the composition of the present invention corresponds to 20.3% of the total dietary fiber content of the composition, and the entire amount may be included as water-soluble dietary fiber.

[0090] Water-soluble dietary fiber components derived from indigestible maltodextrin reach the large intestine without being broken down by digestive enzymes and act as a fermentation substrate for beneficial intestinal bacteria. By dissolving in water and forming a viscous gel, they can maintain moisture in the intestines and alleviate the rise in blood sugar after meals.

[0091] If the content of indigestible maltodextrin is less than 5 parts by weight, it becomes difficult to provide sufficient water-soluble dietary fiber, making it difficult to maintain an appropriate ratio of water-soluble dietary fiber to insoluble dietary fiber in the overall composition, and if it exceeds 5 parts by weight, the balance of the weight ratio with insoluble dietary fiber may decrease due to the excessive supply of water-soluble dietary fiber.

[0092] In addition, a health functional food composition containing complex dietary fiber according to one embodiment of the present invention may include broccoli concentrate powder in an amount of 4 parts by weight.

[0093] Broccoli concentrate powder may contain insoluble dietary fiber including cellulose, hemicellulose and / or lignin.

[0094] The dietary fiber content of the broccoli concentrate powder in the composition of the present invention corresponds to 10% of the total dietary fiber content of the composition, and the entire amount may be included as insoluble dietary fiber.

[0095] Insoluble dietary fiber components derived from broccoli concentrate powder can promote intestinal peristalsis and facilitate the adsorption and excretion of harmful substances in the intestines, while sulforaphane components can perform a protective function for the intestinal mucosa through antioxidant and anti-inflammatory actions.

[0096] If the content of broccoli concentrate powder is less than 4 parts by weight, it is difficult to provide sufficient functional ingredients such as sulforaphane, which may reduce the protective effect on the intestinal mucosa, and if it exceeds 4 parts by weight, the sensory quality of the product may be reduced due to the off-flavor characteristic of broccoli.

[0097] In addition, a health functional food composition containing complex dietary fiber according to one embodiment of the present invention may include carrot juice powder in an amount of 2 parts by weight.

[0098] Carrot juice powder may contain insoluble dietary fiber including cellulose and / or hemicellulose.

[0099] The dietary fiber content of the carrot juice powder in the composition of the present invention corresponds to 7% of the total dietary fiber content of the composition, and the entire amount may be included as insoluble dietary fiber.

[0100] Insoluble dietary fiber components derived from carrot juice powder can increase the water retention capacity in the intestines, thereby increasing stool volume and shortening intestinal transit time, while carotenoid components such as beta-carotene and lutein can alleviate oxidative damage to the intestinal mucosa.

[0101] If the content of carrot juice powder is less than 2 parts by weight, the supply of natural beta-carotene and insoluble dietary fiber is insufficient, which may reduce the complementary effect with beta-carotene-containing preparations, and if it exceeds 2 parts by weight, the characteristic flavor of carrots becomes strong, which may have a negative effect on the palatability of the product.

[0102] In addition, a health functional food composition containing complex dietary fiber according to one embodiment of the present invention may include cabbage extract powder in an amount of 30.5 parts by weight.

[0103] Cabbage extract powder may contain insoluble dietary fiber including cellulose and / or hemicellulose.

[0104] The dietary fiber content of the cabbage extract powder in the composition of the present invention corresponds to 4.5% of the total dietary fiber content of the composition, and the entire amount may be included as insoluble dietary fiber.

[0105] Insoluble dietary fiber components derived from cabbage extract powder promote intestinal peristalsis, and vitamin U (S-methylmethionine) components can repair damage to the gastric and intestinal mucosa and strengthen mucosal protective functions.

[0106] If the content of cabbage extract powder is less than 30.5 parts by weight, it is difficult to provide sufficient vitamin U and insoluble dietary fiber, which may reduce the protective effect on the intestinal mucosa, and if it exceeds 30.5 parts by weight, the sensory quality of the product may be reduced due to the off-flavor and bitter taste characteristic of cabbage.

[0107] In addition, a health functional food composition containing complex dietary fiber according to one embodiment of the present invention may include crystalline cellulose in an amount of 20.7 parts by weight.

[0108] Crystalline cellulose is an insoluble dietary fiber raw material containing cellulose, and the dietary fiber content of the crystalline cellulose in the composition of the present invention corresponds to 32.8% of the total dietary fiber content of the composition, and the entire amount may be included as insoluble dietary fiber.

[0109] Insoluble dietary fiber components derived from crystalline cellulose can increase the volume of stool and promote intestinal peristalsis by absorbing water and expanding in the intestines, and can also act as a binder in the tablet compression process to ensure the hardness and disintegration of the tablet.

[0110] If the content of crystalline cellulose is less than 20.7 parts by weight, it may be difficult to maintain a weight ratio of 1:2 between soluble dietary fiber and insoluble dietary fiber due to a sufficient supply of insoluble dietary fiber, and if it exceeds 20.7 parts by weight, the balance of the weight ratio with soluble dietary fiber may be reduced due to an excessive supply of insoluble dietary fiber.

[0111] In addition, a health functional food composition containing complex dietary fiber according to one embodiment of the present invention may include bamboo extract powder in an amount of 4 parts by weight.

[0112] Bamboo extract powder may contain insoluble dietary fiber including cellulose and / or hemicellulose.

[0113] The dietary fiber content of the bamboo extract powder in the composition of the present invention corresponds to 6.3% of the total dietary fiber content of the composition, and the entire amount may be included as insoluble dietary fiber.

[0114] Insoluble dietary fiber components derived from bamboo extract powder can promote the adsorption and excretion of harmful substances in the intestines and shorten intestinal transit time, and flavonoid compounds can perform a protective function of the intestinal mucosa through antioxidant action.

[0115] If the content of bamboo extract powder is less than 4 parts by weight, it may be difficult to meet the target content of insoluble dietary fiber along with crystalline cellulose, and if it exceeds 4 parts by weight, the balance of the weight ratio with soluble dietary fiber may be reduced due to the excessive supply of insoluble dietary fiber.

[0116] Soluble dietary fiber can create an intestinal fermentation environment by absorbing water and forming a viscous gel, and can act as a fermentation substrate for beneficial bacteria, while insoluble dietary fiber can increase the volume of stool and promote intestinal peristalsis by absorbing water and expanding in the intestines.

[0117] Accordingly, by limiting the weight ratio of soluble dietary fiber to insoluble dietary fiber in a health functional food composition containing complex dietary fiber according to one embodiment of the present invention to 1:2, the two types of dietary fiber can balance their respective physiological functions while ensuring diversity in the production of short-chain fatty acids (SCFAs) and maintaining the balance of intestinal microorganisms.

[0118] In addition, Asians tend to have a relatively high daily intake of insoluble dietary fiber due to their dietary patterns centered on grains and vegetables. Accordingly, by limiting the weight ratio of soluble dietary fiber to insoluble dietary fiber to 1:2, considering the composition of the intestinal microbial community and the characteristics of the fermentation environment, it is possible to balance the function of creating an intestinal fermentation environment by soluble dietary fiber and the function of promoting intestinal peristalsis by insoluble dietary fiber, while ensuring diversity in the production of short-chain fatty acids and maintaining the balance of the intestinal microbiome.

[0119] When the weight ratio of soluble dietary fiber to insoluble dietary fiber is less than 1:2, an excessive proportion of soluble dietary fiber may lead to increased viscosity and reduced mobility of the intestinal contents, which may increase the likelihood of side effects such as abdominal bloating and digestive discomfort.

[0120] In addition, if the weight ratio of soluble dietary fiber to insoluble dietary fiber exceeds 1:2, a decrease in the effect of promoting the growth of beneficial bacteria and a decrease in the production of short-chain fatty acids may occur due to a lack of intestinal fermentation substrates, making it difficult to fully express the effect of improving the intestinal environment.

[0122] From now on, with reference to the attached drawings, a method for manufacturing a health functional food composition containing complex dietary fiber according to one embodiment of the present invention will be described in detail.

[0123] As illustrated in FIG. 1, a method for preparing a health functional food composition containing complex dietary fiber according to one embodiment of the present invention includes a mixing step (S100), a filtration step (S200), a moisture adjustment step (S300) and / or a purification step (S400).

[0124] First, the mixing step (S100) is a step of producing a mixture by mixing 1 part by weight of vitamin B6 hydrochloride, 0.5 parts by weight of beta-carotene, 3.5 parts by weight of powdered vitamin E mixed preparation, 0.5 parts by weight of folic acid, 0.7 parts by weight of vitamin A mixed preparation, 5 parts by weight of ginger concentrate powder, 4 parts by weight of broccoli concentrate powder, 2 parts by weight of carrot juice powder, 30.5 parts by weight of cabbage extract powder, 16.5 parts by weight of banana extract powder, 4.85 parts by weight of asparagus extract powder, 20.7 parts by weight of crystalline cellulose, 4 parts by weight of bamboo extract powder, 1.25 parts by weight of magnesium stearate, and 5 parts by weight of indigestible maltodextrin.

[0125] In the mixing step (S100), each raw material is weighed according to the manufacturing instructions and then weighed according to the mixing ratio and put into a mixer.

[0126] The mixing step (S100) can produce a first mixture by introducing 14 types of raw materials, excluding magnesium stearate, into a mixer and mixing at a rotation speed of 10 to 15 rpm for 20 to 30 minutes, and then adding magnesium stearate and mixing at the same rotation speed for 3 to 5 minutes to produce a final mixture.

[0127] The composition of the present invention includes fat-soluble components sensitive to oxidation, such as beta-carotene and / or a powdered vitamin E mixture, so the mixing step (S100) is preferably performed at room temperature conditions of 15 to 25°C.

[0128] If the temperature exceeds 25℃ during the mixing process, the oxidative decomposition of oxidation-sensitive components is accelerated, which may lead to a decrease in the content of active ingredients and a decline in product quality; therefore, temperature control may be required throughout the mixing process.

[0129] Next, the filtration step (S200) is a step of producing a filtered mixture by passing the mixture produced through the mixing step (S100) through a filter mesh of 1.2 mm or less.

[0130] The filtration step (S200) is a step for removing agglomerates and foreign substances of the raw material powder that may occur during the mixing process to secure a mixture of uniform particle size.

[0131] The composition of the present invention contains a large amount of highly hygroscopic powder raw material, so aggregates may be formed during the mixing step (S100) due to electrostatic attraction between powder particles and moisture adsorption.

[0132] Since the aggregate formed in this way can cause clogging of the tablet press feeder or cause variations in weight and active ingredient content between tablets during the subsequent tableting process (S400), the aggregate can be de-agglomerated through the filtration step (S200) to secure a filtered mixture with uniform particle size.

[0133] If the mesh size of the filter screen exceeds 1.2 mm, aggregates of the raw powder are not sufficiently removed, which may reduce the fluidity of the powder during the tableting process, and if the mesh size is excessively small, it may be difficult for insoluble dietary fiber raw materials with large particle sizes, such as crystalline cellulose, to pass through the filter screen, which may reduce process efficiency.

[0134] Therefore, in the filtration step (S200), by using a filter mesh with a mesh size of 1.2 mm or less, aggregates and foreign substances of the raw powder can be effectively removed, while simultaneously ensuring powder fluidity and particle size uniformity suitable for the tableting process.

[0135] Next, the moisture adjustment step (S300) is a step of adjusting the moisture activity of the filtered mixture generated through the filtration step (S200) to 0.6 AW or less.

[0136] Water activity (AW) is a factor that directly affects the growth of microorganisms and chemical deterioration reactions in food. If the water activity exceeds 0.6 AW, the growth of microorganisms and the hydrolysis of active ingredients are promoted during storage, which may lower the quality and safety of the product.

[0137] Accordingly, in the moisture adjustment step (S300), the moisture activity of the filtered mixture is measured, and if the moisture activity exceeds 0.6 AW, the moisture activity is adjusted to 0.6 AW or less through a dehumidification treatment or drying process.

[0138] Since the composition of the present invention consists entirely of powder raw materials, if the water activity is maintained at 0.6 AW or less after the completion of the mixing step (S100) and / or filtration step (S200), the water adjustment step (S300) can be completed without a separate drying treatment.

[0139] If the water activity exceeds 0.600 AW, the water activity can be adjusted to 0.6 AW or less by a hot air drying method under conditions of 40 to 50℃. Since the decomposition of heat-sensitive components such as beta-carotene and powdered vitamin E mixed preparations may be accelerated if the drying temperature exceeds 50℃, the drying temperature can be set to 50℃ or lower for hot air drying.

[0140] Next, the tableting step (S400) is a step of producing tablets by compressing the filtered mixture, whose water activity has been adjusted through the water adjustment step (S300), into a tablet with a dose of 500 mg ± 4% per tablet using a tablet press.

[0141] In the tableting step (S400), tablets can be formed by applying constant pressure to the filter mixture using the punch and die of a tablet press.

[0142] If the compression pressure is excessive, the disintegration of the tablet may decrease, which may reduce the dissolution rate of the active ingredient, and if the compression pressure is insufficient, the hardness of the tablet may decrease, which may cause the tablet to break during distribution.

[0143] The dosage of the tablet produced in the tableting step (S400) is limited to 500 mg ± 4% per tablet, which corresponds to 480 mg to 520 mg per tablet.

[0144] If the tablet volume deviates from the range of 500 mg ± 4%, the content of the active ingredient per tablet may differ from the design value, which may reduce the functional effect of the product; therefore, the tablet weight can be continuously monitored during the tablet compression process to ensure volume uniformity.

[0145] As described above, according to the health functional food composition containing composite dietary fiber and the method for manufacturing the same according to one embodiment of the present invention, by adopting a composite dietary fiber structure in which soluble dietary fiber and insoluble dietary fiber are combined in a specific weight ratio, a health functional food composition that can contribute to improving the intestinal environment while mitigating side effects that may occur when consuming excessive dietary fiber can be provided.

[0146] In addition, by adjusting the weight ratio of soluble dietary fiber to insoluble dietary fiber to a specific range, the intestinal moisture retention characteristics and the function of promoting intestinal peristalsis can be expressed in a balanced manner, thereby providing a beneficial effect for intestinal health management.

[0147] In addition, through the design of a composition containing various plant-derived extract powders along with complex dietary fiber, the intestinal environment-improving function of dietary fiber and the nutritional function of plant-derived bioactive components can be expressed complementarily.

[0148] In addition, by including vitamin-based compounds, it is possible to realize a health functional food composition capable of providing a balanced combination of nutritional components along with the functional effects of dietary fiber and plant-derived extract powder.

[0150] The operation and effects of the invention will be explained in more detail below through specific embodiments. However, these are presented merely as examples of the invention and do not limit the scope of the invention in any way.

[0152] Example 1

[0153] 1g of vitamin B6 hydrochloride, 0.5g of beta-carotene (beta-carotene content 10 wt%), 3.5g of powdered vitamin E mixed preparation, 0.5g of folic acid, 0.7g of vitamin A mixed preparation, 5g of ginger concentrate powder (active ingredient content 20 wt%), 4g of broccoli concentrate powder, 2g of carrot juice powder, 30.5g of cabbage extract powder (active ingredient content 2 wt%), 16.5g of banana extract powder, 4.85g of asparagus extract powder (active ingredient content 1 wt%), 20.7g of crystalline cellulose, 4g of bamboo extract powder, 1.25g of magnesium stearate, and 5g of indigestible maltodextrin were prepared.

[0154] All raw materials except magnesium stearate were put into a mixer and mixed at a rotation speed of 15 rpm for 25 minutes to produce a first mixture, then magnesium stearate was added and mixed at the same rotation speed for 5 minutes to produce a final mixture.

[0155] Afterwards, the generated mixture was filtered by passing it through a filter screen with a mesh size of 1.2 mm or less, and then dried by being placed in a hot air dryer at 45°C to achieve a water activity of 0.45 AW. Afterward, it was placed in a tablet press and compressed into a tablet with a volume of 500 mg to produce a tablet.

[0156] Example 2

[0157] 1g of vitamin B6 hydrochloride, 0.5g of beta-carotene (beta-carotene content 5 wt%), 3.5g of powdered vitamin E mixed preparation, 0.5g of folic acid, 0.7g of vitamin A mixed preparation, 5g of ginger concentrate powder (active ingredient content 10 wt%), 4g of broccoli concentrate powder, 2g of carrot juice powder, 30.5g of cabbage extract powder (active ingredient content 1 wt%), 16.5g of banana extract powder, 4.85g of asparagus extract powder (active ingredient content 0.5 wt%), 20.7g of crystalline cellulose, 4g of bamboo extract powder, 1.25g of magnesium stearate, and 5g of indigestible maltodextrin were prepared.

[0158] All raw materials except magnesium stearate were put into a mixer and mixed at a rotation speed of 15 rpm for 25 minutes to produce a first mixture, then magnesium stearate was added and mixed at the same rotation speed for 5 minutes to produce a final mixture.

[0159] Afterwards, the generated mixture was filtered by passing it through a filter screen with a mesh size of 1.2 mm or less, and then dried by being placed in a hot air dryer at 45°C to achieve a water activity of 0.45 AW. Afterward, it was placed in a tablet press and compressed into a tablet with a volume of 500 mg to produce a tablet.

[0160] Comparative Example 1

[0161] 1g of vitamin B6 hydrochloride, 0.5g of beta-carotene (beta-carotene content 10 wt%), 3.5g of powdered vitamin E mixed preparation, 0.5g of folic acid, 0.7g of vitamin A mixed preparation, 5g of ginger concentrate powder (active ingredient content 20 wt%), 4g of broccoli concentrate powder, 2g of carrot juice powder, 30.5g of cabbage extract powder (active ingredient content 2 wt%), 16.5g of banana extract powder, 4.85g of asparagus extract powder (active ingredient content 1 wt%), 1.25g of magnesium stearate, and 29.7g of indigestible maltodextrin were prepared.

[0162] All raw materials except magnesium stearate were put into a mixer and mixed at a rotation speed of 15 rpm for 25 minutes to produce a first mixture, then magnesium stearate was added and mixed at the same rotation speed for 5 minutes to produce a final mixture.

[0163] Afterwards, the generated mixture was filtered by passing it through a filter screen with a mesh size of 1.2 mm or less, and then dried by being placed in a hot air dryer at 45°C to achieve a water activity of 0.45 AW. Afterward, it was placed in a tablet press and compressed into a tablet with a volume of 500 mg to produce a tablet.

[0164] Comparative Example 2

[0165] 1g of vitamin B6 hydrochloride, 0.5g of beta-carotene (beta-carotene content 10 wt%), 3.5g of powdered vitamin E mixed preparation, 0.5g of folic acid, 0.7g of vitamin A mixed preparation, 5g of ginger concentrate powder (active ingredient content 20 wt%), 4g of broccoli concentrate powder, 2g of carrot juice powder, 30.5g of cabbage extract powder (active ingredient content 2 wt%), 16.5g of banana extract powder, 4.85g of asparagus extract powder (active ingredient content 1 wt%), 25.7g of crystalline cellulose, 4g of bamboo extract powder, and 1.25g of magnesium stearate were prepared.

[0166] All raw materials except magnesium stearate were put into a mixer and mixed at a rotation speed of 15 rpm for 25 minutes to produce a first mixture, then magnesium stearate was added and mixed at the same rotation speed for 5 minutes to produce a final mixture.

[0167] Afterwards, the generated mixture was filtered by passing it through a filter screen with a mesh size of 1.2 mm or less, and then dried by being placed in a hot air dryer at 45°C to achieve a water activity of 0.45 AW. Afterward, it was placed in a tablet press and compressed into a tablet with a volume of 500 mg to produce a tablet.

[0168] Comparative Example 3

[0169] 1g of vitamin B6 hydrochloride, 0.5g of beta-carotene (beta-carotene content 10 wt%), 3.5g of powdered vitamin E mixed preparation, 0.5g of folic acid, 0.7g of vitamin A mixed preparation, 5g of ginger concentrate powder (active ingredient content 20 wt%), 4g of broccoli concentrate powder, 2g of carrot juice powder, 30.5g of cabbage extract powder (active ingredient content 2 wt%), 16.5g of banana extract powder, 4.85g of asparagus extract powder (active ingredient content 1 wt%), 8g of crystalline cellulose, 4g of bamboo extract powder, 1.25g of magnesium stearate, and 17.7g of indigestible maltodextrin were prepared.

[0170] All raw materials except magnesium stearate were put into a mixer and mixed at a rotation speed of 15 rpm for 25 minutes to produce a first mixture, then magnesium stearate was added and mixed at the same rotation speed for 5 minutes to produce a final mixture.

[0171] Afterwards, the generated mixture was filtered by passing it through a filter screen with a mesh size of 1.2 mm or less, and then dried by being placed in a hot air dryer at 45°C to achieve a water activity of 0.45 AW. Afterward, it was placed in a tablet press and compressed into a tablet with a volume of 500 mg to produce a tablet.

[0173] Experimental Example 1 - Evaluation of Effects of Promoting Intestinal Peristalsis and Inhibiting Intestinal Gas Production

[0174] In order to evaluate the effects of the compositions of Examples 1 and 2 and Comparative Examples 1 to 3 on intestinal peristalsis and intestinal gas production, intestinal mobility measurement tests and intestinal gas production amount measurement tests were conducted.

[0175] ICR male mice (7 weeks old, body weight 30±2g) were assigned to groups of 10, and the compositions of Examples 1 and 2 and Comparative Examples 1 to 3 were orally administered daily for 2 weeks at a concentration of 200 mg / kg based on solid content.

[0176] After the administration was finished, mice were fasted for 16 hours, and then an activated charcoal suspension (charcoal meal, 10% activated charcoal in 5% gum arabic solution) was orally administered at a dose of 0.1 mL / 10 g.

[0177] After 30 minutes of administering the activated charcoal suspension, mice were sacrificed and their small intestines were removed. The intestinal transit rate (%) was calculated as the ratio of the distance traveled by the activated charcoal to the total length of the small intestine from the pylorus to the cecum.

[0178] Intestinal gas production was measured by collecting intestinal gas expelled from mice for 24 hours using a closed metabolic cage under identical administration conditions, and measuring the concentrations (ppm) of hydrogen (H₂) and methane (CH₄) gases using gas chromatography. The measurement results are shown in Table 1 below.

[0179] division Ministerial turnover rate (%) H2 concentration (ppm) CH4 concentration (ppm) Total gas volume (ppm) Example 1 67.6 18.4 12.1 30.5 Example 2 61.5 22.3 15.4 37.7 Comparative Example 1 46.4 38.7 26.2 64.9 Comparative Example 2 53.4 29.1 18.8 47.9 Comparative Example 3 50.8 33.5 22.6 56.1

[0180] As shown in Table 1 and Figure 2, Example 1 showed the highest value with an intestinal transit rate of 67.6%, and the lowest total intestinal gas production was measured at 30.5 ppm. Example 2 showed the next best results after Example 1, with an intestinal transit rate of 61.5% and a total gas production of 37.7 ppm.

[0181] On the other hand, Comparative Examples 1 to 3 showed a lower intestinal mobility rate of 46.4 to 53.4% ​​compared to Examples 1 and 2, and a higher total gas production of 47.9 to 64.9 ppm compared to Examples 1 and 2.

[0182] In particular, Comparative Example 1, which contained only water-soluble dietary fiber, was measured to have the highest total gas production at 64.9 ppm, confirming that gas production due to intestinal over-fermentation increases when water-soluble dietary fiber is used alone.

[0183] Accordingly, the composition of Example 1, containing soluble dietary fiber and insoluble dietary fiber in a weight ratio of 1:2, was found to be more advantageous for improving intestinal function by simultaneously exhibiting the effect of promoting intestinal peristalsis and the effect of inhibiting intestinal gas production compared to Comparative Examples 1 to 3, which have different ratios of dietary fiber.

[0184] In addition, since Example 1 uses a composition in which the content of active ingredients such as beta-carotene, ginger concentrate powder, cabbage extract powder, and asparagus extract powder is set to an appropriate level, it is judged that the effect of promoting intestinal peristalsis and improving the intestinal environment is superior compared to Example 2.

[0185] Experimental Example 2 - Evaluation of Intestinal pH and Mucosal Protective Effect

[0186] In order to evaluate the effects of the compositions of Examples 1 and 2 and Comparative Examples 1 to 3 on the intestinal pH environment and mucosal protection, an intestinal pH measurement test and a mucin secretion measurement test were performed.

[0187] 10 male SD rats (7 weeks old, body weight 200±20g) were assigned to each group, and the compositions of Examples 1 to 2 and Comparative Examples 1 to 3 were orally administered daily for 4 weeks at a concentration of 200 mg / kg based on solid content.

[0188] After the administration was finished, rats were sacrificed and the contents of the small and large intestines were collected, and the pH of the small and large intestines was measured using a pH meter.

[0189] To evaluate the mucosal protective effect, colonic mucosal tissue was collected, the number of mucin-secreting cells was counted using Alcian blue staining, and the mucin protein content (μg / mg tissue) was quantified using ELISA. The measurement results are shown in Table 2 below.

[0190] division Small intestine pH Colon pH Number of mucin-secreting cells (cells / mm²) 2 ) Mucin content (μg / mg) Example 1 6.8 6.2 187 4.83 Example 2 6.9 6.4 172 4.41 Comparative Example 1 7.3 6.9 134 3.12 Comparative Example 2 7.1 6.7 141 3.38 Comparative Example 3 7.2 6.8 148 3.57

[0191] As shown in Table 2 and Figure 3, Example 1 exhibited the lowest pH values ​​with a small intestine pH of 6.8 and a large intestine pH of 6.2, and showed the best results in mucosal protection indicators with a mucin-secreting cell count of 187 cells / mm² and a mucin content of 4.83 μg / mg. Example 2 showed the next best results after Example 1 with a small intestine pH of 6.9, a large intestine pH of 6.4, a mucin-secreting cell count of 172 cells / mm², and a mucin content of 4.41 μg / mg.

[0192] On the other hand, Comparative Examples 1 to 3 were measured to have a small intestine pH of 7.1 to 7.3 and a large intestine pH of 6.7 to 6.9, which were higher than Examples 1 and 2, and the number of mucin-secreting cells was measured to be 134 to 148 cells / mm² and the mucin content was measured to be 3.12 to 3.57 μg / mg, which were lower than Examples 1 and 2.

[0193] Accordingly, the composition of Example 1, containing soluble dietary fiber and insoluble dietary fiber in a weight ratio of 1:2, was found to be the most effective in maintaining the intestinal pH and mucosal environment by maintaining the intestinal pH in an acidic direction and promoting mucin secretion.

[0194] In addition, since Example 1 uses a composition in which the content of active ingredients such as beta-carotene, ginger concentrate powder, cabbage extract powder, and asparagus extract powder is set to an appropriate level, it is judged that the intestinal pH control and mucosal protection effects are superior compared to Example 2.

[0195] Experimental Example 3 - Evaluation of the effect of alleviating digestive burden after a high-fat diet

[0196] To evaluate the effect of the compositions of Examples 1 and 2 and Comparative Examples 1 to 3 on relieving digestive burden after a high-fat diet, gastric emptying and postprandial blood triglyceride measurement tests were conducted.

[0197] Male C57BL / 6J mice (8 weeks old, body weight 22±2g) were assigned to groups of 10, and the compositions of Examples 1 to 2 and Comparative Examples 1 to 3 were orally administered daily for 2 weeks at a concentration of 200 mg / kg based on solid content.

[0198] After the administration was finished, mice were fasted for 16 hours, and then a high-fat test diet (fat content 40%, olive oil-based) was orally administered at a dose of 0.2 mL / 10 g.

[0199] Two hours after administering the test meal, blood was collected from the orbital vein to separate the serum, and postprandial blood triglycerides (TG, mg / dL) were measured using an automated biochemical analyzer. At this time, the preprandial blood TG level was 105 mg / dL in all experimental groups, which was the same condition.

[0200] Gastric emptying rate was measured using the Phenol Red dietary evaluation method, and a smaller amount of dye remaining in the stomach indicates smoother gastric motility. The measurement results are shown in Table 3 below.

[0201] division Gastric discharge rate (%) Postprandial blood TG (mg / dL) Increase in TG (mg / dL) compared to before administration Example 1 64.3 143 38 Example 2 58.7 159 54 Comparative Example 1 44.2 198 93 Comparative Example 2 51.6 182 77 Comparative Example 3 48.3 191 86

[0202] As shown in Table 3 and Figures 4 to 6, Example 1 demonstrated the most excellent effect in relieving digestive burden, with a gastric emptying rate of 64.3%, a postprandial blood TG of 143 mg / dL, and an increase in TG of +38 mg / dL compared to before administration. Example 2 showed the next best results after Example 1, with a gastric emptying rate of 58.7%, a postprandial blood TG of 159 mg / dL, and an increase in TG of +54 mg / dL.

[0203] On the other hand, Comparative Examples 1 to 3 showed a gastric emptying rate of 44.2 to 51.6%, which was lower than that of Examples 1 and 2, and the increase in blood TG after a meal was measured to be +77 to +93 mg / dL, which was higher than that of Examples 1 and 2, so the effect of alleviating the digestive burden after a high-fat diet was limited.

[0204] Therefore, it was confirmed that the composition of Example 1, containing soluble dietary fiber and insoluble dietary fiber in a weight ratio of 1:2, exhibited the most superior effect in terms of alleviating the digestive burden after overeating and high-fat diets.

[0205] In addition, since Example 1 uses a composition in which the content of active ingredients such as beta-carotene, ginger concentrate powder, cabbage extract powder, and asparagus extract powder is set to an appropriate level, it is judged that it showed a superior effect compared to Example 2 in terms of increasing gastric emptying rate and inhibiting the increase of blood triglycerides after meals.

[0207] Although all components constituting the embodiments of the present invention have been described above as being combined or operating in combination, the present invention is not necessarily limited to such embodiments. That is, within the scope of the purpose of the present invention, all components may be selectively combined in one or more ways to operate.

[0208] Furthermore, terms such as "include," "compose," or "have" described above, unless specifically stated otherwise, mean that the relevant component may be inherent; therefore, they should be interpreted as allowing for the inclusion of additional components rather than excluding them. All terms, including technical or scientific terms, have the same meaning as generally understood by those skilled in the art to which the present invention pertains, unless otherwise defined. Commonly used terms, such as those defined in advance, should be interpreted in accordance with their meaning in the context of the relevant technology and should not be interpreted in an ideal or overly formal sense unless explicitly defined in the present invention.

[0209] Furthermore, the above description is merely an illustrative explanation of the technical concept of the present invention, and those skilled in the art to which the present invention pertains will be able to make various modifications and variations within the scope of the essential characteristics of the present invention.

[0210] Accordingly, the embodiments disclosed in this invention are intended to illustrate, not limit, the technical concept of the invention, and the scope of the technical concept of the invention is not limited by these embodiments. The scope of protection of this invention shall be interpreted by the claims below, and all technical concepts within an equivalent scope shall be interpreted as being included within the scope of rights of this invention.

Claims

Claim 1 A health functional food composition containing complex dietary fiber comprising 1 part by weight of vitamin B6 hydrochloride, 0.5 parts by weight of beta-carotene, 3.5 parts by weight of powdered vitamin E mixed preparation, 0.5 parts by weight of folic acid, 0.7 parts by weight of vitamin A mixed preparation, 5 parts by weight of ginger concentrate powder, 4 parts by weight of broccoli concentrate powder, 2 parts by weight of carrot juice powder, 30.5 parts by weight of cabbage extract powder, 16.5 parts by weight of banana extract powder, 4.85 parts by weight of asparagus extract powder, 20.7 parts by weight of crystalline cellulose, 4 parts by weight of bamboo extract powder, 1.25 parts by weight of magnesium stearate, and 5 parts by weight of indigestible maltodextrin. Claim 2 delete Claim 3 A health functional food composition according to claim 1, wherein the weight ratio of water-soluble dietary fiber to insoluble dietary fiber contained in the composition is 1:2, and the composition contains a complex dietary fiber. Claim 4 A health functional food composition containing complex dietary fiber according to claim 1, wherein the beta-carotene is a beta-carotene-containing preparation having a beta-carotene content of 10 wt%, the ginger concentrate powder is a concentrate powder having a ginger-derived active ingredient content of 20 wt%, the cabbage extract powder is an extract powder having a cabbage-derived active ingredient content of 2 wt%, and the asparagus extract powder is an extract powder having an asparagus-derived active ingredient content of 1 wt%. Claim 5 A mixing step of producing a mixture by mixing 1 part by weight of vitamin B6 hydrochloride, 0.5 parts by weight of beta-carotene, 3.5 parts by weight of powdered vitamin E mixed preparation, 0.5 parts by weight of folic acid, 0.7 parts by weight of vitamin A mixed preparation, 5 parts by weight of ginger concentrate powder, 4 parts by weight of broccoli concentrate powder, 2 parts by weight of carrot juice powder, 30.5 parts by weight of cabbage extract powder, 16.5 parts by weight of banana extract powder, 4.85 parts by weight of asparagus extract powder, 20.7 parts by weight of crystalline cellulose, 4 parts by weight of bamboo extract powder, 1.25 parts by weight of magnesium stearate, and 5 parts by weight of indigestible maltodextrin; a filtration step of producing a filtered mixture by passing the mixture through a filter screen with a mesh size of 1.2 mm or less; and a moisture adjustment step of adjusting the water activity of the filtered mixture to 0.6 AW or less. A method for manufacturing a health functional food composition containing complex dietary fiber, comprising a tableting step of producing tablets by compressing the filtered mixture, with adjusted water activity, into a dose of 500 mg ± 4% per tablet.

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