A hydrogel composition for relieving skin swelling comprising plant-derived natural compounds and plant extracts as active ingredients

Abstract

The present invention relates to a hydrogel composition for alleviating skin edema, promoting blood circulation, and cooling the skin, and provides a hydrogel composition comprising: a polymeric gelling agent; a moisturizer; one or more compounds selected from troxerutin and escin; and caffeine.

Description

Technology Field

[0001] The present invention relates to a hydrogel composition based on natural ingredients, and more specifically, to a functional hydrogel composition that effectively relieves skin edema by including plant-derived natural compounds and plant extracts as active ingredients. Background Technology

[0002] Skin edema is a temporary or chronic physiological abnormality of the skin caused by various factors, and it frequently appears particularly in areas such as the face, eyes, jawline, and neck.

[0003] Edema primarily occurs due to the excessive accumulation of interstitial fluid within tissues, and its causes involve a highly complex range of factors, including reduced blood circulation, impaired lymphatic circulation, fluid retention, lack of sleep, excessive salt intake, allergies, external stimuli, inflammatory responses, and aging.

[0004] Consequently, skin swelling causes not only changes in appearance but also various physical and psychological discomforts, such as skin pressure, tightness, heat, and fatigue.

[0005] Conventionally, various types of cosmetics and functional compositions have been developed to alleviate such skin edema. Among them, the most common approach is formulation technology that induces cooling of the skin.

[0006] A method has been widely used to induce temporary vasoconstriction and soothing effects and reduce swelling by utilizing menthol, camphor, alcohol-based compounds, and hydrogels with high water content to deliver a direct cooling sensation to the skin.

[0007] In particular, mask packs in the form of cooling gels or hydrogel sheets have been widely used for the purpose of temporarily relieving swelling, and they have the advantage of being gentle on the skin and providing an excellent cooling sensation. However, it has been pointed out that these products mostly only provide sensory or external improvements and do not address the root cause of edema.

[0008] In addition, compositions utilizing plant extracts that promote moisture excretion or induce improved circulation have been proposed for some products.

[0009] For example, seaweed extracts, green tea extracts, hop extracts, and camellia extracts have been widely used as ingredients expected to have antioxidant and astringent effects, and have been applied as an auxiliary means to improve skin swelling.

[0010] However, most of these plant-derived ingredients focus on general benefits such as moisturizing, soothing, and antioxidant effects, while designs or ingredient combinations specifically tailored for alleviating skin swelling are lacking.

[0011] Meanwhile, conventional technology has also included methods for alleviating swelling that utilize massage and mechanical stimulation. This approach improves lymphatic circulation and temporarily relieves swelling by physically stimulating the skin using tools such as rollers, vibrators, and cooling massagers.

[0012] While such mechanical stimulation methods can be expected to produce physical effects, they have problems such as skin irritation, difficulty in consistent use, and limited portability. Above all, it is difficult to expect a sustained effect when used alone without combined action with a hydrogel composition.

[0013] Meanwhile, with the recent expansion of the functional cosmetics market, research on active ingredients for improving skin condition is also being actively conducted.

[0014] Nevertheless, conventional cosmetics for reducing swelling still rely on a single specific ingredient or focus simply on sensory cooling effects, so compositions with a combination of ingredients or mechanisms of action systematically designed to address the complex causes of skin edema are rare.

[0015] Furthermore, compositions that combine functionality and longevity while ensuring low irritation and stability sufficient for repeated use on sensitive areas (e.g., around the eyes, cheeks, etc.) are not yet sufficiently supplied commercially.

[0016] Against this backdrop, there is a steady demand for compositions that can be used without burdening the skin and demonstrate substantial effects in alleviating skin edema through various physiological mechanisms, and there is a need for the development of technology to satisfy this demand. The problem to be solved

[0017] The present invention is intended to solve the aforementioned problems, and the objective of the present invention is to provide a skin-friendly hydrogel composition that minimizes skin irritation and maximizes the effect of alleviating skin edema through a combination of complex active ingredients. means of solving the problem

[0018] According to one aspect of the present invention, a hydrogel composition for alleviating skin edema is provided, comprising: a polymer gelling agent; a moisturizer; one or more compounds selected from troxerutin and escin; and caffeine.

[0019] In one embodiment, the hydrogel composition may further include magnolol; and honokiol.

[0020] In one embodiment, the hydrogel composition may further include Arnica montana flower extract; and Butcher's broom root extract.

[0021] In one embodiment, the hydrogel composition may further include artichoke leaf extract.

[0022] In one embodiment, the hydrogel composition may further include pumpkin extract and red bean extract.

[0023] In one embodiment, the hydrogel composition may further include guarana seed extract.

[0024] In one embodiment, the hydrogel composition may be processed into a sheet of a predetermined shape.

[0025] According to another aspect of the present invention, a hydrogel composition for promoting blood circulation is provided, comprising a polymer gelling agent; a humectant; one or more compounds of troxerutin and escin; and caffeine.

[0026] According to another aspect of the present invention, a hydrogel composition for skin cooling is provided, comprising a polymer gelling agent; a moisturizer; one or more compounds selected from troxerutin and escin; and caffeine. Effects of the invention

[0027] According to the present invention, the hydrogel composition can effectively relieve skin swelling while minimizing skin irritation by including plant-derived natural compounds and plant extracts as active ingredients.

[0028] The above hydrogel composition can exhibit a more substantial and sustained edema relief effect compared to compositions focused on simple cooling, because the complex active ingredients induce complex physiological effects such as improved blood and lymphatic circulation, anti-inflammatory, soothing, and fluid balance regulation through different mechanisms of action.

[0029] The effects of the present invention are not limited to the effects described above, and should be understood to include all effects that can be inferred from the configuration of the invention described in the detailed description of the invention or the claims. Specific details for implementing the invention

[0030] The terms used in this specification have been selected based on currently widely used general terms whenever possible, taking into account their functions in the present invention; however, these terms may vary depending on the intent of those skilled in the art, case law, the emergence of new technologies, etc. Additionally, in specific cases, terms have been arbitrarily selected by the applicant, and in such cases, their meanings will be described in detail in the relevant description of the invention. Therefore, the terms used in this invention should be defined not merely by their names, but based on their meanings and the overall content of the invention.

[0031] Unless otherwise defined, all terms used herein, including technical or scientific terms, have the same meaning as generally understood by those skilled in the art to which the present invention pertains. Terms such as those defined in commonly used dictionaries should be interpreted as having a meaning consistent with their meaning in the context of the relevant technology, and should not be interpreted in an ideal or overly formal sense unless explicitly defined in this application.

[0032] Numerical ranges include the values ​​defined in the above ranges. All maximum numerical limits given throughout this specification include all lower numerical limits as clearly written. All minimum numerical limits given throughout this specification include all higher numerical limits as clearly written. All numerical limits given throughout this specification will include all better numerical ranges within a wider numerical range, as clearly written.

[0033] The embodiments of the present invention are described in detail below, but it is obvious that the present invention is not limited by the following embodiments.

[0034] One aspect of the present invention provides a hydrogel composition for alleviating skin edema comprising a polymeric gelling agent; a moisturizer; one or more compounds selected from troxerutin and escin; and caffeine.

[0035] The above hydrogel composition contains plant-derived complex natural compounds and plant extracts as active ingredients, allowing for safe use with minimal irritation, and can effectively improve skin edema through a complex mechanism of action.

[0036] The above hydrogel layer composition is formed by crosslinking chains of hydrophilic polymers to form a three-dimensional network structure, and can be composed of water-soluble or water-dispersible polymer materials containing water, and has the characteristics of supplying moisture to the skin and adhering comfortably.

[0037] The above hydrogel is formed by cross-linking polymer chains through a polymer gelling agent, and has a high water content, serving to continuously supply moisture to the skin while simultaneously delivering active ingredients within the gel to the skin.

[0038] The hydrogel composition according to the present invention can provide various functions such as providing a cooling sensation, supplying moisture, and relieving irritation, and is therefore suitable for the purpose of relieving skin edema.

[0039] The above-mentioned polymer gelling agent is a major component that forms the basic three-dimensional network structure of the hydrogel composition of the present invention, and imparts gel-state properties that can maintain a certain shape while containing moisture.

[0040] When applied to the skin, the gelling agent provides appropriate viscoelasticity along with a cooling effect, adheres to the skin surface, and enables the local application of active ingredients.

[0041] The above gelling agent may be carrageenan, agar, carob gum, xanthan gum, gellan gum, cellulose gum, algin, glucomannan, galactomannan, guar gum, polyacrylate or its salt, polymethacrylic acid, carboxyvinyl polymer, polyvinyl alcohol, polyacrylamide, polyethylene oxide, polyvinylpidolidone, methylcellulose, cellulose, carboxymethylcellulose, and hydroxyethylcellulose, and these may be used alone or in a mixture of two or more.

[0042] In particular, by combining the synthetic polymer or natural polymer as the gelling agent into a double network structure, the hydrogel of the present invention can simultaneously achieve high strength and excellent moisture retention.

[0043] In addition, by adjusting the concentration of the gelling agent and the amount of the crosslinking agent, the gelling temperature, viscosity, hardness, etc., can be varied, which can contribute to improved applicability depending on the area of ​​skin edema.

[0044] The above moisturizer can be included in the hydrogel composition to prevent moisture loss from the skin and increase moisture content, thereby contributing to maintaining the hydration state of the skin.

[0045] In particular, the area where skin edema has occurred is sensitive to external stimuli, and the moisturizer can alleviate skin irritation and promote skin recovery by supplying moisture and forming a moisturizing barrier.

[0046] The above moisturizer may include commonly used polyhydric alcohols, specifically glycerin, butylene glycol (BG), propylene glycol (PG), sorbitol, diglycerin, 1,2-hexanediol, etc., and may be used alone or in a mixture of two or more, but is not limited thereto.

[0047] The above moisturizer can assist in the penetration of active ingredients within the hydrogel or improve the water-holding capacity of the hydrogel, thereby maintaining a cooling and moisturizing sensation on the skin even after prolonged application. In addition, the above moisturizer can prevent drying shrinkage of the hydrogel, which can contribute to improved shape stability and usability when used in the form of a patch or mask.

[0048] The above “Troxerutin” may refer to a derivative of rutin, a natural flavonoid compound derived mainly from corn that exhibits vascular protective, antioxidant, and anti-inflammatory effects.

[0049] The above-mentioned troxerutin is useful for relieving local edema caused by blood stagnation by contributing to the reduction of capillary permeability and the strengthening of blood vessel walls. The above-mentioned troxerutin can protect skin barrier function by suppressing inflammatory responses through free radical scavenging action and contribute to blocking inflammation-inducing pathways, which are one of the causes of edema.

[0050] The above “Aescin” is Marronnier ( Aesculus hippocastanum As a natural saponin-based compound derived from the seeds of ) it can promote the reabsorption of body fluid leaked into tissues due to increased vascular permeability and promote the absorption and removal of edema by improving lymphatic flow.

[0051] The aforementioned escin has vascular stabilization and venous circulation improvement functions similar to troxerutin, but since their mechanisms of action differ, when used together, superior capillary protection and edema relief effects can be expected through their complementary action.

[0052] Specifically, while the above-mentioned troxerutin focuses primarily on protecting the blood vessel wall based on flavonoid-based antioxidant functions, the above-mentioned escin can inhibit fluid leakage by directly regulating the permeability of vascular endothelial cells through its saponin structure.

[0053] The above hydrogel composition can secure a key mechanism of action, namely vascular stabilization, by selectively including one or more of the above troxerutin and escin.

[0054] Meanwhile, the aforementioned “caffeine” is a natural alkaloid compound derived from coffee beans, green tea, etc., and when applied topically to the skin, it induces a vasoconstriction effect and can contribute to alleviating symptoms such as skin edema and eye edema through physiological activities such as promoting lymphatic circulation and lipid breakdown.

[0055] The aforementioned caffeine reduces fluid retention in areas of blood stagnation within the skin and can have a positive effect on reducing swelling as well as improving dark circles and complexion.

[0056] When the above caffeine is used in combination with troxerutin or escin, the microcirculation-promoting action works in combination, enabling the realization of edema-relieving effects based on various mechanisms in a more multi-layered and sustained form.

[0057] The above hydrogel composition may further include magnolol; and honokiol.

[0058] The above “Magnolol” refers to a natural lignan compound derived from the bark of plants of the genus Magnolia (Magnolia spp.), which has anti-inflammatory and antioxidant active ingredients structurally similar to honokiol.

[0059] The above-mentioned magnolol inhibits the NF-κ pathway and COX-2 expression that cause excessive inflammatory responses in the skin, and when used together with the above-mentioned honokiol, it can effectively suppress skin irritation responses through the mutual synergy between these similar lignan compounds and can also help restore the skin barrier.

[0060] The above “Honokiol” is magnolia ( Magnolia officinalis It is a natural lignan compound with a biphenyl structure derived from tree bark, and is a functional ingredient that helps relieve skin stress through anti-inflammatory, antioxidant, and soothing effects. In particular, the above honokiol can contribute to the improvement of edema by selectively inhibiting inflammation-inducing pathways such as NF-κMAPK, thereby reducing inflammation-induced vasodilation and fluid leakage.

[0061] In addition, when the above-mentioned troxerutin and escin are used in combination with honokiol, magnolol, etc., anti-inflammatory and antioxidant effects act in parallel with the vascular stabilizing effect, which can lead to the complex improvement of local inflammatory fluid retention and microvascular damage, which are one of the main causes of skin edema.

[0062] Meanwhile, the hydrogel composition may further include Arnica montana flower extract; and Butcher's broom root extract.

[0063] The above “Arnica Montana flower extract” is a natural product extracted from the flowers of the Arnica Montana plant, which belongs to the Asteraceae family, and has been used to relieve bruises, pain, and inflammation. The above Arnica Montana flower extract can play an important role in soothing facial swelling by relieving inflammation around capillaries and promoting tissue regeneration.

[0064] The above “Butcher’s broom root extract” is a natural extract obtained from the root of Butcher’s broom (Ruscus aculeatus), a plant of the Liliaceae family, and contains saponin-based active ingredients such as ruscogenin and neoruscogenin, and has peripheral vasoconstriction and lymphatic flow improvement effects, so it can achieve an effect on skin edema caused by reduced blood flow and fluid circulation.

[0065] Each of the above active ingredients can contribute to the improvement of skin edema through an independent mechanism of action, but they can exhibit a more excellent effect by acting complementarily and organically in the hydrogel composition of the present invention.

[0066] For example, the above-mentioned troxerutin or escin works together with caffeine to provide improved vascular permeability and antioxidant effects, magnolol and honokiol block additional edema-inducing factors by inhibiting inflammation-inducing signals, and arnica montana flower extract supports the recovery and soothing of skin tissue, while butcher's broom root extract promotes lymphatic circulation to induce the drainage of already accumulated fluids.

[0067] Accordingly, the hydrogel composition can promote physical and physiological stability by activating circulation in the area when applied to the skin through the combined action of the main active ingredients, rapidly alleviating inflammatory edema and stagnant edema, and simultaneously providing a cooling sensation and moisturizing effect.

[0068] The above hydrogel composition for relieving skin edema may further include artichoke leaf extract.

[0069] The above “artichoke leaf extract” is artichoke ( Cynara scolymusIt is a natural plant extract derived from the leaves of a plant, containing cynarin, luteolin, chlorogenic acid, etc. as its main components, and is known to exhibit antioxidant, anti-inflammatory, diuretic, and skin microcirculation improvement effects.

[0070] The above artichoke leaf extract can directly act to resolve lymphatic stagnation, which is one of the major causes of skin edema, and flavonoid components such as luteolin contained in artichoke leaves can contribute to the simultaneous improvement of inflammatory edema and circulatory edema by performing vascular permeability inhibition and anti-inflammatory effects.

[0071] When the above artichoke leaf extract is applied together with the above active ingredients, multiple physiological pathways of anti-inflammatory, antioxidant, blood flow promotion, and lymphatic circulation improvement are organically combined, thereby enabling a more comprehensive and stable effect of alleviating skin edema.

[0072] Therefore, the above artichoke leaf extract can provide a fundamental response to the causes of edema and can be particularly effective against swelling caused by water retention or edema resulting from reduced lymphatic circulation.

[0073] The above hydrogel composition for alleviating skin edema may further include pumpkin extract; and red bean extract.

[0074] The above “pumpkin extract” is Cucurbita moschata It refers to a plant extract obtained from pumpkin fruits of similar varieties, containing components such as vitamin C, beta-carotene, potassium, and flavonoids.

[0075] The potassium abundant in the above-mentioned pumpkin promotes the excretion of sodium from the body and regulates osmotic pressure balance, which can contribute to the alleviation of temporary edema caused by water retention, and the antioxidant components beta-carotene and flavonoids induce a soothing effect on skin inflammatory reactions, which is effective in indirectly suppressing the causes of edema.

[0076] The above “red bean extract” is Vigna angularis It refers to an extract of (red bean) seeds, which may contain bioactive substances such as saponins, flavonoids, and polyphenols. The above red beans are traditionally known to have diuretic and swelling-reducing effects, and may contribute to promoting the drainage of fluids within tissues and improving lymphatic circulation.

[0077] The above-mentioned pumpkin extract and red bean extract can perform complementary functions in terms of relieving water retention in the body or local tissues and promoting lymphatic flow, and this can realize a more precise physiological regulation-based edema relief effect through combination with vascular stabilizing and anti-inflammatory active ingredients such as troxerutin, honokiol, and escin.

[0078] The above hydrogel composition for alleviating skin edema may further include guarana seed extract.

[0079] The above “guarana seed extract” is Paullinia cupana It refers to a plant extract derived from plant seeds, containing various bioactive components such as natural caffeine, theobromine, tannins, and polyphenols. Natural caffeine, a major component of guarana, can contribute to the alleviation of skin edema by temporarily constricting blood vessels and promoting the removal of excess moisture from tissues.

[0080] In particular, components such as theobromine and polyphenols contained in the above guarana extract provide antioxidant and anti-inflammatory effects, thereby alleviating and soothing skin irritation, and can also suppress the occurrence of inflammatory edema caused by external stimuli.

[0081] Therefore, the hydrogel composition containing the guarana seed extract can more effectively and safely improve temporary or recurring skin edema through various mechanisms of action.

[0082] In the present invention, “extract” refers to a natural component obtained by separating and concentrating an active ingredient from a specific part of a plant (e.g., flower, leaf, root, seed, etc.) using a solvent such as ethanol, water, glycol, or oil.

[0083] The above plant extract is a naturally derived ingredient that causes minimal skin irritation and is rich in bioactive components, making it widely used as a cosmetic ingredient.

[0084] In particular, the above plant extracts contain physiologically active substances unique to each source plant (e.g., flavonoids, saponins, phenolic acids, alkaloids, tannins, terpenoids, etc.) and can exhibit various physiological activities such as improving blood flow, anti-inflammatory, antioxidant, soothing, promoting lymphatic circulation, moisturizing, and protecting the skin.

[0085] The functional effects of the above plant extract can be further enhanced not only by the effects of a single component but also through synergistic interactions between complex components, and can act in various ways on diverse physiological phenomena such as local inflammation, stagnant blood and lymph flow, increased microvascular permeability, and fluid accumulation in tissues, which are among the major causes of edema.

[0086] In addition, since the content and composition of the active ingredients vary depending on the extraction solvent, temperature, time, and concentration method of the above extract, it is possible to secure ingredients with high stability and biocompatibility through an optimized extraction process.

[0087] The form of the above-mentioned extract can be selected in various ways depending on the formulation of the composition.

[0088] For example, when a water-soluble active ingredient is the main component, it exists in the form of a liquid extract or concentrate, which is suitable for water-based formulations such as lotions, essences, and mask packs. On the other hand, when a large amount of oil-soluble ingredients are contained, it is obtained as an oil extract, which is advantageous for application in oil-based formulations such as oils, creams, and balms.

[0089] In addition, the extract can also be used as a powder extract for long-term storage and high-concentration formulations, which can be prepared by spray drying or freeze-drying methods. The powder extract is advantageous for increasing formulation stability and extending shelf life, and can be easily applied to compositions such as creams, powders, and gels.

[0090] Another aspect of the present invention provides a hydrogel composition for promoting blood circulation comprising a polymeric gelling agent; a humectant; one or more compounds selected from troxerutin and escin; and caffeine.

[0091] The above hydrogel composition, by including one or more compounds and natural extracts, can be usefully applied to improve skin microcirculation and alleviate skin problems caused by blood stagnation.

[0092] The above “promotion of blood circulation” means facilitating the flow of capillaries and lymph within the skin tissue to improve symptoms such as changes in skin color, edema, fatigue, and loss of elasticity caused by fluid retention or impaired blood flow.

[0093] In particular, blood and lymphatic circulation in peripheral areas such as the face and legs plays an important role in maintaining skin health, and combinations of functional ingredients that improve this can be widely applied in the fields of beauty and skin treatment.

[0094] Another aspect of the present invention provides a hydrogel composition for skin cooling comprising a polymeric gelling agent; a moisturizer; one or more compounds selected from troxerutin and escin; and caffeine.

[0095] The above hydrogel composition can effectively lower skin temperature elevated by the external environment or skin heat through its formulation characteristics and complex components, and can soothe the skin and provide a cooling sensation.

[0096] The above "skin cooling" refers to lowering the temperature of the skin surface by physical, physiological, or psychological means to alleviate an overheated state and to relieve symptoms such as erythema, stinging, and burning caused by an increase in skin temperature. In particular, the above hydrogel composition can simultaneously provide skin barrier protection and soothing effects through a skin cooling effect in situations such as high-temperature environments in summer, outdoor activities, exposure to ultraviolet rays, inflammatory reactions, and after cosmetic procedures.

[0097] In the present invention, the hydrogel composition can be processed into a sheet of a predetermined shape.

[0098] The above hydrogel composition can be processed into various forms suitable for application to the skin, and in particular, by being manufactured in the form of a sheet that adheres closely to the face, the effect of alleviating skin edema can be maximized.

[0099] The above hydrogel contains a large amount of moisture and has excellent viscoelasticity, so when molded to a certain thickness, it is easy to attach to the skin and has excellent adhesion, which allows the active ingredients to be stably delivered to the skin.

[0100] In particular, the hydrogel composition processed into a sheet form can flexibly adhere to the curves of the entire face, allowing it to be evenly applied to areas with many curves, such as the forehead, cheeks, around the nose, and the chin.

[0101] Since the above hydrogel composition is intended to alleviate facial edema, it is desirable to process it into a sheet form so that it can be applied uniformly over the entire face rather than to localized areas. To this end, the composition is generally gelled to a thickness of 1.0 to 8.0 mm, and then cut to fit the facial contour or automatically shaped using a mold.

[0102] The above method for producing the sheet-type hydrogel can generally be formed by mold filling or film or fabric coating of a hydrogel composition in a high-temperature sol state, followed by a cooling process, and if necessary, a mesh support layer or a film substrate may be attached.

[0103] In addition, the hydrogel composition can be processed into a facial sheet and designed to be refrigerated or used immediately, and when actually used, it can contribute to soothing the edematous area and promoting circulation along with a cooling effect.

[0104] Meanwhile, the above hydrogel composition may further include a chelating agent, a pH adjuster, and a crosslinking agent.

[0105] The above chelating agent plays a role in inducing a chelating action against metal ions, and for example, disodium EDTA, EDTA, EDTA-2 sodium, calcium citrate, sodium citrate, organic acid salts thereof, organic bases thereof, or mixtures thereof may be used, but are not limited thereto.

[0106] The above pH adjuster may be selected from one or more of the group consisting of tartaric acid, urea, ammonia, ammonium phosphate, sodium bicarbonate, triethanolamine, potassium hydroxide, amino acids, asiatic acid, sodium hydroxide, citric acid, sodium citrate, tromethamine, and arginine, but is not limited thereto.

[0107] The above-mentioned crosslinking agent is preferably a polyvalent metal salt and may be, for example, one or more selected from the group consisting of aluminum glycinate, aluminum hydroxide, hydrated aluminum silicate, aluminum acetate, aluminum lactate, aluminum stearate, calcium chloride, magnesium chloride, aluminum chloride, magnesium aluminum metasilicate, calcium lactate, calcium chloride, potassium chloride, and magnesium aluminum silicate, but is not limited thereto.

[0108] In addition, the hydrogel composition may further include additives such as preservatives, fragrances, surfactants, skin active ingredients, etc., as needed, and the types of said additives are not particularly limited.

[0109] The above preservative may be selected from one or more of the group consisting of caprylyl glycol, alkyl parahydroxybenzoate esters, benzoic acid, sodium benzoate, sorbic acid, potassium sorbate, phenoxyethanol, parabens, pentanediol, salicylic acid, dihydroacetic acid or salts thereof, ethylhexylglycerin, 1,2-hexanediol and p-oxybenzoic acid esters, but is not limited thereto.

[0110] The above surfactant comprises: a polyhydric alcohol comprising glyceryl monostearate, polyglyceryl-4 isostearate, sorbitan monostearate, and sugar ester monostearate; a polyoxyethylene methylpolysiloxane copolymer comprising fatty acid ester-based PEG-8 dimethicone, PEG-10 dimethicone, PEG-9 methyl ether dimethicone, PEG-3 dimethicone, and PEG-11 methyl ether dimethicone; and a poly(oxyethylene·oxypropylene) methylpolysiloxane copolymer comprising PEG / PPG-20 / 20 butyl ether dimethicone and PEG / PPG-20 / 20 dimethicone. It may be one or more selected from the group consisting of alkyl chain-silicone chain branched poly(oxyethylene, oxypropylene)methylpolysiloxane copolymers including cetyl PEG / PPG 10 / 1-dimethicone and lauryl PEG-9 polydimethylsiloxyethyldimethicone, but is not limited thereto.

[0111] The above skin active ingredients may be one or more selected from the group consisting of, for example, arbutin, niacinamide, vitamin C, vitamin B5, vitamin E, retinol, coenzyme Q10, adenosine, and natural extracts, but are not limited thereto.

[0112] The above natural extracts may be one or more selected from the group consisting of extracts of aloe, green tea, ginseng, red ginseng, wood vinegar, pine needles, ginkgo leaves, propolis, mulberry leaves, silkworms, Kakadu plum, camu camu, yasai palm, squalane, caviar, broccoli, blueberry, witch hazel, acerola, chlorella, mangosteen, guava, Cornus fruit, carrot, caffeine, witch hazel, spirulina, salmon roe, Ecklonia cava, giant kelp, kelp, Portulaca oleracea, green laver, agar-agar, mulberry root, raspberry, wild strawberry, Sargassum, Edelweiss, chamomile, lavender, peppermint, eucalyptus, lemon balm, oregano, tea tree, Scutellaria baicalensis, Houttuynia cordata, and sea buckthorn, but are not limited thereto.

[0113] The above hydrogel composition can optimize the physical properties, stability, and usability of the hydrogel through a combination of various components to control physical properties as intended.

[0114] The present invention will be further described in detail through the following examples, but it is obvious that the present invention is not limited by the following examples.

[0115] Examples and Comparative Examples

[0116] In order to verify the functionality of the hydrogel composition of the present invention, examples and comparative examples were established by mixing the compositions as shown in Tables 1 and 2 below. Each component was purchased from the market and used.

[0117] The composition other than the active ingredient used in the examples and comparative examples was formulated identically, and in order to realize a hydrogel formulation, it was processed into a sheet form according to a general aqueous-based hydrogel manufacturing process including a polymer gelling agent (e.g., carrageenan, carob gum, etc.), a humectant (glycerin), a pH adjuster (tromethamine), a crosslinking agent (e.g., calcium salt or aluminum salt, etc.), and a preservative.

[0118] Each sample was adjusted to have the same gelation conditions, viscosity, and pH (5.8) to enable comparative evaluation, and the effects of skin edema relief, blood flow improvement, and cooling effects were evaluated based on a single component or combination of components.

[0119] [Content (parts by weight)] division Examples 1 2 3 4 5 6 7 8 9 10 Troxeroutine 60 - 40 30 30 40 - 30 25 25 Essin - 60 40 30 30 - 40 30 25 25 caffeine 60 60 40 30 30 40 40 30 30 25 Magnoli - - - 15 - 10 10 10 10 10 Honokiol - - - 15 - 10 10 10 10 10 Arnica montana flower extract - - - - 15 10 10 5 5 5 Butcher's broom root extract - - - - 15 10 10 5 5 5 artichoke leaf extract - - - - - - - 5 5 5 Pumpkin extract - - - - - - - - 5 5 Red bean extract - - - - - - - - 5 5 Guarana seed extract - - - - - - - - - 5

[0120] [Content (parts by weight)] division Comparative example 1 2 3 4 5 6 7 8 Troxeroutine 120 - - - - - 30 - Essin - 120 - - - - 30 - caffeine - - 120 - - - - - Magnoli - - - 120 - - - - Honokiol - - - - 120 - - - Arnica montana flower extract - - - - - 60 30 20 Butcher's broom root extract - - - - - 60 30 20 artichoke leaf extract - - - - - - - 20 Pumpkin extract - - - - - - - 20 Red bean extract - - - - - - - 20 Guarana seed extract - - - - - - - 20

[0121] Experimental Example 1: Evaluation of swelling-relieving activity

[0122] The effect of the hydrogel compositions of the examples and comparative examples on the alleviation of skin edema was evaluated.

[0123] The experiment was conducted on healthy adult women aged 20 to under 50, and the subjects applied each hydrogel sheet once a day for a total of 7 days to the eye area and cheekbone area.

[0124] The degree of swelling before and after sheet application is measured using a high-resolution facial 3D scanner (Vectra ® The volume of the central facial area (under the eyes and cheekbone area) was evaluated using H2, Canfield Scientific Inc., and swelling relief activity was quantitatively analyzed based on the volume reduction rate (%) after 7 days (Table 3).

[0125] division Percentage of change in facial volume (%) Example 1 -16.8 Example 2 -17.6 Example 3 -20.8 Example 4 -23.8 Example 5 -24.1 Example 6 -22.7 Example 7 -22.1 Example 8 -25.8 Example 9 -30.1 Example 10 -31.6 Comparative Example 1 -5.1 Comparative Example 2 -6.2 Comparative Example 3 -4.6 Comparative Example 4 -6.0 Comparative Example 5 -9.1 Comparative Example 6 -10.4 Comparative Example 7 -13.1 Comparative Example 8 -12.8

[0126] Referring to Table 3, Examples 1 to 10 all showed a swelling reduction rate of -16.8% to -31.6%, which was significantly better than the range of -4.6% to -13.1% of Comparative Examples 1 to 8.

[0127] In particular, Example 10 showed a high swelling reduction rate of -31.6%, indicating that the synergistic effect was maximized when troxerutin, escin, caffeine, magnolol, honokiol, and complex natural extracts were applied together.

[0128] When comparing Example 5 and Comparative Example 7, a clear difference in effect is shown depending on whether caffeine is added, with Example 5 showing -24.1% and Comparative Example 7 showing -13.1%, indicating a significant difference in effect.

[0129] In addition, Comparative Examples 1 to 5 based on a single component and Comparative Examples 6 and 8 containing only combinations of plant extracts also showed relatively insufficient activity compared to the Examples.

[0130] The above results suggest that the swelling-relieving effect can be enhanced by combining natural extracts with major active compounds such as troxerutin, escin, and caffeine, and that activity can be further improved through the complex composition.

[0131] Experimental Example 2: Evaluation of Blood Circulation Promoting Activity

[0132] The blood circulation-promoting activity of hydrogel compositions according to examples and comparative examples was evaluated.

[0133] As an evaluation method, changes in microvascular blood flow on the skin surface were quantitatively measured using a non-invasive Laser Doppler Flowmetry (LDF).

[0134] Healthy adult female volunteers were selected, and hydrogel sheets of the examples and comparative examples were applied to the inner upper arm.

[0135] Blood flow was measured before and 60 minutes after application, respectively, and the blood circulation promoting effect was evaluated based on the percentage increase compared to before application (Table 4).

[0136] The application and measurement of the hydrogel sheet were performed under indoor conditions of 22±1℃ and 45±5% humidity.

[0137] division Blood flow increase rate (%) Example 1 14.1 Example 2 14.9 Example 3 17.9 Example 4 21.5 Example 5 24.2 Example 6 19.2 Example 7 20.9 Example 8 24.5 Example 9 28.2 Example 10 29.5 Comparative Example 1 4.0 Comparative Example 2 4.9 Comparative Example 3 3.4 Comparative Example 4 5.2 Comparative Example 5 7.8 Comparative Example 6 9.0 Comparative Example 7 12.4 Comparative Example 8 11.1

[0138] Referring to Table 4, Examples 1 to 10 all showed a double-digit increase in blood flow rate, and in particular, Examples 5, 8 to 10 showed high values ​​exceeding 20%.

[0139] The above results are interpreted as the result of multiple active ingredients acting complementarily to induce relaxation of peripheral blood vessels, improvement of microvascular circulation, and increase in blood flow velocity.

[0140] In the case of Examples 9 and 10, the compositions included pumpkin extract, red bean extract, or guarana seed extract, and it was evaluated that the diuretic and circulatory-supporting effects derived from herbal medicines acted in combination.

[0141] In particular, Example 10 showed the highest blood flow increase rate of 29.5% among all compositions, so it is determined that the combination of various functional extracts exhibited synergistic efficacy.

[0142] On the other hand, Comparative Examples 1 to 5 were single-compound based compositions, and the mechanism of each component was limited to a local level and failed to induce a complex blood flow promoting effect.

[0143] Comparative Examples 6 and 8 also consisted of compositions containing only natural extracts, and their effects were limited compared to the composite composition of the example.

[0144] The above results indicate that the complex active ingredients in the composition of the present invention interact organically to exert a synergistic effect on increasing blood flow through complex mechanisms such as vasodilation, activation of microcirculation, and alleviation of inflammation, and suggest that this can be extended to skin beauty improvement effects such as skin tone improvement and enhanced supply of oxygen and nutrients, in addition to alleviating swelling.

[0145] Experimental Example 3: Evaluation of Skin Cooling Activity

[0146] The skin cooling activity of the hydrogel compositions of the examples and comparative examples was evaluated.

[0147] The study was conducted on healthy adult women aged 25 to 55, and participants were instructed to stop using high-performance products that could affect the skin barrier starting one week prior to the study.

[0148] After applying a hydrogel sheet to the forearm of the subject, the change in skin temperature at 20 minutes was measured using a thermal imaging camera (FLIR E6, FLIR Systems Inc., USA).

[0149] Cooling activity was quantitatively evaluated based on the decrease in temperature (°C) after application compared to before application of the hydrogel sheet (Table 5).

[0150] division Temperature decrease (°C) Example 1 -2.8 Example 2 -2.7 Example 3 -3.0 Example 4 -3.5 Example 5 -3.9 Example 6 -3.4 Example 7 -3.6 Example 8 -4.0 Example 9 -4.4 Example 10 -4.5 Comparative Example 1 -1.4 Comparative Example 2 -1.6 Comparative Example 3 -1.4 Comparative Example 4 -1.6 Comparative Example 5 -1.6 Comparative Example 6 -1.8 Comparative Example 7 -2.1 Comparative Example 8 -2.0

[0151] Referring to Table 5, Examples 1 to 10 of the present invention all exhibited a cooling effect that significantly reduced skin temperature.

[0152] On the other hand, Comparative Examples 1 to 5 were compositions containing only a single compound component, and only a negligible cooling effect of -1.4°C to -1.6°C was observed, and Comparative Examples 6 and 8, which contained only natural extracts, also had limited cooling effects.

[0153] The above results suggest that the skin cooling effect can be enhanced through the synergistic activity of the present complex formulation, and that the hydrogel composition of the present invention can be effectively utilized as a functional topical composition that can simultaneously provide skin soothing, a cooling sensation, relief of heat sensation, and improvement of swelling when used in practice.

[0154] The foregoing description of the present invention is for illustrative purposes only, and those skilled in the art will understand that other specific forms can be easily modified without altering the technical spirit or essential features of the present invention. Therefore, the embodiments described above should be understood as illustrative in all respects and not restrictive. For example, each component described as a single unit may be implemented in a distributed manner, and components described as distributed may likewise be implemented in a combined form.

[0155] The scope of the present invention is defined by the claims set forth below, and all modifications or variations derived from the meaning and scope of the claims and equivalent concepts thereof should be interpreted as being included within the scope of the present invention.

Claims

Claim 1 A hydrogel composition for alleviating skin edema comprising a polymer gelling agent; a moisturizer; troxerutin; escin; caffeine; magnolol; and honokiol; and further comprising arnica montana flower extract; and butcher's broom root extract as active ingredients. Claim 2 delete Claim 3 delete Claim 4 A hydrogel composition for alleviating skin edema, wherein, in claim 1, it further comprises artichoke leaf extract. Claim 5 A hydrogel composition for alleviating skin edema according to claim 1, further comprising: pumpkin extract; and red bean extract. Claim 6 A hydrogel composition for alleviating skin edema, wherein, in claim 1, it further comprises guarana seed extract. Claim 7 A hydrogel composition for alleviating skin edema, processed into a sheet shape of a predetermined shape in any one of claims 1 and 4 to 6. Claim 8 A hydrogel composition for promoting blood circulation comprising a polymer gelling agent; a moisturizer; troxerutin; escin; caffeine; magnolol; and honokiol; and further comprising arnica montana flower extract; and butcher's broom root extract as active ingredients. Claim 9 A hydrogel composition for skin cooling comprising a polymer gelling agent; a moisturizer; troxerutin; escin; caffeine; magnolol; and honokiol; and further comprising arnica montana flower extract; and butcher's broom root extract as active ingredients.

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