A system for management information using cell culture dish which integrated displaying information

Abstract

The present invention relates to a culture dish and an information management system using the same, wherein an information display unit consisting of a QR code or a barcode on at least one side of the outer surface is utilized on a plurality of culture dishes where bacterial culture is completed so that information selected from a measurement location, measurement time, bacterial count, and inoculated bacteria is input, thereby automatically generating a test report necessary for validation.

Description

Technology Field

[0001] The present invention relates to an information management system using an information-displaying culture dish that automatically generates a report required for validation by utilizing an information display unit, consisting of a QR code or a barcode on at least one side of the outer surface, on a plurality of culture dishes where bacterial culture is completed, so that information selected from the measurement location, measurement time, bacterial count, and inoculated bacteria is input. Background Technology

[0002] In the pharmaceutical industry, contamination can lead to fatal consequences.

[0003] This not only threatens the safety of patients, employees, and the environment but can also impact the business.

[0004] While maintaining a high level of hygiene is important, controlling biological burden levels through effective cleaning alone is not enough.

[0005] Identifying and preventing possible pollutants is just as important.

[0006] The most common contaminants found in pharmaceuticals include physical contaminants, such as chips, particles, and fibrous materials, which can enter the manufacturing or packaging process and contaminate the entire batch; pyrogens, which are microorganisms that can cause fever; chemical contaminants, such as moisture, gas, vapor, or molecules, which can also contaminate sterile pharmaceuticals; and biological components, such as viruses, bacteria, or fungi, which can cause disease and should not be found in pharmaceuticals.

[0007] Furthermore, to effectively prevent contamination and ensure a high level of safety in pharmaceutical manufacturing, it is crucial to identify sources of contamination and take definitive preventive measures once sources that could potentially contaminate pharmaceutical processes and products have been identified. As a means to achieve this, GMP (Good Manufacturing Practice) is utilized to manufacture high-quality food and pharmaceuticals with high safety by minimizing contamination that may occur during the pharmaceutical manufacturing process, and various requirements for compliance with the aforementioned GMP are presented.

[0008] As a means related to such technology, registered utility model No. 489614 presents a technology for a diagnostic kit for environmental monitoring, and the configuration provides a diagnostic kit (1) for field environment monitoring comprising a first culture medium surface (12) cultured on one side of a first culture vessel (11), a second culture medium surface (22) cultured on one side of a second culture vessel (21), and a diagnostic unit (10) completed by joining the back side of the first culture vessel (11) and the back side of the second culture vessel (21).

[0009] And, the above-mentioned diagnostic kit (1) for field environment monitoring can double-monitor by inspecting the first culture medium surface (12) and the second culture medium surface (22) cultured in each culture medium, with different or identical environments, and the back surface of the first culture medium (11) and the back surface of the second culture medium (21) are joined together by being placed against a holder (30) equipped with a stick-shaped handle (31).

[0010] However, while the aforementioned diagnostic kit allows for easy identification of on-site contamination levels, it has the disadvantage of making it difficult to apply a systematic system based on standardized test report management. The problem to be solved

[0011] The objective of the present invention, which aims to resolve the aforementioned conventional disadvantages, is to provide an information management system using an integrated information display dish that enables systematic management of contamination levels, allows for easy identification of on-site contamination levels, enables contamination management, and facilitates easy on-site application. means of solving the problem

[0012] To achieve the above objective, the present invention provides an information display integrated culture dish having an information display portion on at least one side of an outer surface so as to input one or more pieces of information selected from a measurement location, a measurement time, a number of bacteria, and inoculated bacteria.

[0013] In addition, the information display unit provides an information display integrated culture dish comprising any one selected from RF tags, QR codes, and barcodes.

[0015] Meanwhile, the present invention comprises a cartridge having an information display section that accommodates a plurality of culture dishes and discharges one or more of them sequentially, and

[0016] A camera provided on one side of the lower part of the above cartridge to check information on the discharged culture dish

[0017] The present invention provides an information management system using an information display integrated culture dish comprising a control unit connected to the above-mentioned camera and installed to automatically generate a test report by a predetermined program.

[0018] In addition, the control unit of the present invention provides an information management system using an information display integrated culture dish, which is installed to simultaneously input the measurement location, measurement time, and inoculated bacteria by pre-preparing a test report form, and to simultaneously check the number of bacteria cultured in the culture dish by means of a program and an image captured through a camera.

[0019] In addition, the control unit of the present invention provides an information management system using an information display-integrated culture dish, wherein the control unit is equipped with a printer to print a report or to generate a report file at regular intervals according to a pre-stored program and remotely transmit it externally.

[0020] In addition, the cartridge of the present invention comprises an assembly structure of a casing having an input port and an output port and a storage unit having a mounting hole that is rotatably installed inside the cartridge, thereby enabling mounting and discharge of multiple culture dishes, and the discharged culture dishes are installed to be transported to one side by a conveyor installed at the bottom of the cartridge, thereby providing an information management system using an information display-integrated culture dish. Effects of the invention

[0021] As described above, according to the present invention, systematic management of contamination levels is possible, the contamination level at the site can be easily identified, the contamination level at the site can be identified in real time and immediate action can be taken, and the contamination level can be managed through a configuration in which modules are installed, thereby providing the effect of easy on-site application. Brief explanation of the drawing

[0022] FIG. 1 is a perspective view illustrating a conventional diagnostic kit for environmental monitoring. FIG. 2 is a schematic diagram illustrating a culture dish according to the present invention. FIG. 3 is an application state diagram of an information management system using a culture dish according to the present invention. FIG. 4 is an exploded view of the key parts illustrating a cartridge according to the present invention. Specific details for implementing the invention

[0023] Hereinafter, embodiments of the present invention will be described in detail based on the attached drawings.

[0024] FIG. 2 is a schematic diagram illustrating a culture dish according to the present invention, FIG. 3 is an application state diagram of an information management system using a culture dish according to the present invention, and FIG. 4 is an exploded view of a key part illustrating a cartridge according to the present invention.

[0025] The present invention performs GMP certification, which is a certification procedure to verify whether requirements to be observed throughout the entire manufacturing and quality control process, from process control to shipment, are being followed in order to manufacture and supply quality-assured pharmaceuticals, medical devices, cosmetics, etc.

[0026] At this time, for the aforementioned GMP certification, the pharmaceutical company manages and verifies contamination levels according to a predetermined management plan, and performs microbiological tests (manufacturing water, airborne bacteria, suspended bacteria, surface bacteria) at checkpoints located in areas where contamination has occurred or is expected to occur; appropriate culture dishes are used for these microbiological tests.

[0027] And, the culture dish (100) is provided with an information display unit (110) on at least one side of its outer surface so that one or more selected from the measurement location, measurement time, number of bacteria, and inoculated bacteria are input.

[0028] Additionally, the culture dish (100) comprises a base (101) on which a culture medium (102) is placed and a cover sheet (105) covering the base, and the information display portion may be formed on the cover sheet.

[0029] At this time, the information display unit (110) is composed of one or more selected from RF tags, QR codes, and barcodes.

[0030] Additionally, the information display unit (110) may be printed directly on the culture dish or printed on it, or may be printed on a printout or attached to the culture dish after being printed.

[0031] At this time, the above-mentioned output paper is configured to have a release liner attached, so that it is installed to be easily attached to a culture dish when separated.

[0033] Meanwhile, the information display system (300) of the present invention is configured to include a cartridge (310), a camera (330), and a control unit (350).

[0034] And, the cartridge (310) is installed such that one or more spaces are formed to accommodate a plurality of culture dishes (100) having information display sections, and one or more are discharged sequentially from the bottom.

[0035] At this time, the cartridge (310) is provided with a casing (311) having an inlet (312) and an outlet (314) formed therein, and a storage unit (315) that stores a plurality of culture dishes in a circumferential direction while rotating inside the casing, and a pusher (317) is installed in the casing so that a culture dish falls to the center of the storage unit. In addition, the storage unit (315) is installed to rotate inside the casing and is composed of a plurality of assembly structures having mounting holes so that a plurality of culture dishes can be mounted and discharged.

[0036] Additionally, the camera (330) is installed on one side of the discharge port (314) formed in the cartridge to photograph the information display portion of the culture dish (100) falling onto the table (400).

[0037] At this time, a table (400) that moves in a straight line or rotates is provided on the lower side of the discharge port and is installed so that the falling culture dish is discharged after moving.

[0038] And, the control unit (350) is connected to the camera and installed to automatically generate a test report by a predetermined program.

[0039] At this time, the control unit (350) may be installed so that a test report form is prepared in advance and the measurement location, measurement time, inoculated bacteria, number of bacteria, etc. are simultaneously input, and the number of bacteria may be installed so that the number of bacteria cultured in a culture dish is simultaneously checked by a program upon receiving an image captured through a camera.

[0040] In addition, the control unit (350) is further equipped with a printer (357) to print a report, automatically generate and save a report file at regular intervals according to a pre-stored program, or remotely transmit it externally via a wireless unit (351).

[0041] At this time, the control unit (350) is assigned a unique ID.

[0042] The operation of the present invention, configured as described above, is explained.

[0043] As illustrated in FIGS. 2 to 4, the present invention collects airborne or falling bacteria by opening a culture dish for a certain period of time at a checkpoint located in an area where contamination has occurred or is expected to occur, so as to manage and verify the contamination level according to a predetermined management plan.

[0044] At this time, the information display unit (110) provided in the culture dish (100) is configured such that information regarding the measurement location and measurement time is printed in advance or printed before installation at the checkpoint, so that measurement is taken at a predetermined time at a predetermined location.

[0045] In addition, the information display unit (110) provided in the culture dish (100) allows information about the measurement location and measurement time to be input by printing or printing after collecting airborne bacteria or falling bacteria at a certain measurement time at a certain location of the checkpoint.

[0046] Additionally, the culture dish (100) is composed of a base (101) on which a culture medium (102) is placed and a cover sheet (105) that covers the base, so that when the cover sheet is opened, bacteria contaminated in the culture medium are collected (inoculated), and when the cover sheet is closed after collection is completed, an information display section (110) is formed on the cover sheet.

[0047] At this time, the information display unit (110) is composed of one or more selected from RF tags, QR codes, and barcodes, and may be printed directly on a culture dish or printed on a printout or attached to a culture dish after being printed on a printout.

[0048] Then, the bacteria inoculated into the culture dish (100) are cultured in a culture vessel (not shown) having certain culture conditions, and the number of bacteria after culture is completed is read and displayed on the information display unit (110).

[0049] At this time, the information display unit (110) may display the measurement location and measurement time that were previously entered after the operator reads the number of bacteria, and may also simultaneously enter the measurement location, measurement time, number of bacteria, inoculated bacteria, etc.

[0050] In addition, the information display unit (110) that displays information including the number of bacteria as described above also uses the method of direct printing or attaching a printed sheet as described above.

[0051] That is, the culture dish (100) in which culture is completed through the above configuration is equipped with an information display unit (110) that can identify the measurement location, measurement time, number of bacteria, inoculated bacteria, etc., so that reading by a camera in a subsequent process is possible.

[0052] Meanwhile, the present invention is equipped with an information display system (300) that organizes information on each culture dish (100) collected from a plurality of measurement points as described above by automation, thereby making it easy to manage the contamination level of each measurement point after measurement is completed.

[0053] In addition, the above information display system (300) is composed of a cartridge (310) that accommodates a plurality of culture dishes (100), a camera (330) that reads information of culture dishes discharged from the cartridge, and a control unit (350) that organizes and outputs the read information, thereby enabling contamination level management through automation.

[0054] Additionally, the cartridge (310) is installed to sequentially discharge and allow for sequential verification of information on multiple culture dishes stored, with one or more spaces formed to accommodate multiple culture dishes (100) having information display sections.

[0055] That is, the cartridge (310) is configured such that the input port (312) and the output port (314) are formed in a casing (311), a storage unit (315) is installed to store a plurality of culture dishes in a circumferential direction while rotating inside the casing, and a pusher (317) is installed in the casing so that when the pusher is operated, individual culture dishes fall to the center of the storage unit, thereby allowing the information of a plurality of culture dishes to be checked sequentially.

[0056] Additionally, a camera (330) is installed on one side of the discharge port (314) formed in the cartridge to photograph the information display portion of the culture dish (100) falling onto the table (400), and the photographed image is transmitted to the control unit (350).

[0057] At this time, a table (400) that moves in a straight line or rotates is provided on the lower side of the discharge port so that it moves and discharges the falling culture dish after the photographing is completed.

[0058] And, the control unit (350) is connected to the camera and automatically generates a report that can identify the measurement location, measurement time, number of bacteria, inoculated bacteria, etc., by means of a predetermined program.

[0059] In addition, the control unit (350) is further equipped with a printer to print a report or to form a report file at regular intervals according to a pre-stored program and to be installed to remotely transmit it externally via a wireless unit (351), thereby enabling efficient management, and the control unit (350) is assigned a unique ID so that it is easy to verify the source of the transmitted data. Explanation of the symbols

[0060] 100...Coverage dish 110...Information display 310...Cartridge 330...Camera 350...control unit

Claims

Claim 1 delete Claim 2 delete Claim 3 A cartridge installed to sequentially discharge multiple culture dishes, each consisting of a base on which a culture medium is placed and a cover sheet having an information display section on at least one side of the outer surface to store information selected from measurement location, measurement time, bacterial count, and inoculated bacteria; a camera installed on one side of the discharge port of the cartridge to check information of the discharged culture dishes on a table that rotates infinitely; and a control unit connected to the camera and installed to automatically generate a test report according to a predetermined program, wherein the cartridge comprises: a) a casing installed having an input port on the upper perimeter and an output port on the lower side of the central part; b) multiple storage units installed on the inside of the casing in which multiple culture dishes are stacked to rotate along the perimeter of the output port; c) a pusher installed on one side of the casing to drop only the culture dishes placed in one storage unit to the output port in the center of the storage unit; d) the culture dishes discharged by the pusher installed to drop onto a table installed on the lower part of the cartridge and be transported to one side; and the control unit, wherein a test report form is prepared in advance Information management system using an information display integrated culture dish, which is installed to simultaneously input the measurement location, measurement time, and inoculated bacteria, and to simultaneously check and input the number of bacteria cultured in the culture dish by a programmed camera. Claim 4 delete Claim 5 In paragraph 3, the information management system using an information display integrated culture dish is characterized in that the control unit is equipped with a printer to print a report or to form a report file at regular intervals according to a pre-stored program and remotely transmit it externally. Claim 6 delete

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