Cannabinoid-Terpenoid Compositions and Cultivation methods for Microbiome Modulation, Neuroimmune Homeostasis, and Treatment od Addiction and Chronic Diseases through safe and effective pharmacolo-gical, neurobiological, and psychological remodeling machanisms of the brain's reward centers

Abstract

This invention relates to the cultivation of female cannabis strains rich in secondary cannabinoids and terpenes under controlled environmental stress conditions, as well as the formulation of therapeutic compounds combining these compounds with terpenes extracted from pine trees. These formulations work by modulating the microbiome balance, activating neuroimmune pathways, and remodeling the brain's reward centers to treat addiction and chronic diseases. This invention encompasses culture protocols and extraction methods, delivery systems, and clinical applications targeting gastrointestinal, neuroimmunological, and psychiatric disorders. It also provides scalable methods for producing rare chemotides and standardized formulations for pharmaceutical, industrial, and agricultural applications.